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Information on EC 2.5.1.126 - norspermine synthase

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IUBMB Comments
The enzyme, characterized from the thermophilic archaeon Pyrobaculum aerophilum, can also synthesize norspermidine from propane-1,3-diamine and thermospermine from spermidine (with lower activity). The long-chain polyamines stabilize double-stranded DNA at high temperatures. In contrast to EC 2.5.1.127, caldopentamine synthase, this enzyme does not accept norspermine as a substrate.
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The expected taxonomic range for this enzyme is: Archaea, Eukaryota
Synonyms
long-chain polyamine synthase, PaSpeE, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl 3-(methylsulfanyl)propylamine + norspermidine = S-methyl-5'-thioadenosine + norspermine
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PATHWAY SOURCE
PATHWAYS
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