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Information on EC 2.5.1.103 - presqualene diphosphate synthase

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IUBMB Comments
Isolated from the green alga Botryococcus braunii BOT22. Unlike EC 2.5.1.21, squalene synthase, where squalene is formed in one step from farnesyl diphosphate, in this alga the intermediate presqualene diphosphate is generated and released by this enzyme. This compound is then converted into either squalene (by EC 1.3.1.96, Botryococcus squalene synthase) or botryococcene (EC 1.3.1.97, botryococcene synthase).
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Word Map
  • 2.5.1.103
  • botryococcus
  • braunii
  • ubiquitin-conjugating
  • ubiquitin-proteasome
  • botryococcene
  • ataxin-1
  • evolutionally
  • ataxia
  • spinocerebellar
  • triterpene
The expected taxonomic range for this enzyme is: Botryococcus braunii
Synonyms
ssl-1, squalene synthase-like, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 (2E,6E)-farnesyl diphosphate = presqualene diphosphate + diphosphate
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