Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 2.5.1.10 - (2E,6E)-farnesyl diphosphate synthase and Organism(s) Panax ginseng and UniProt Accession Q4JHN6

for references in articles please use BRENDA:EC2.5.1.10
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB Comments
Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. The enzyme will not accept larger prenyl diphosphates as efficient donors.
Specify your search results
Select one or more organisms in this record: ?
This record set is specific for:
Panax ginseng
UNIPROT: Q4JHN6
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The taxonomic range for the selected organisms is: Panax ginseng
The enzyme appears in selected viruses and cellular organisms
Synonyms
farnesyl diphosphate synthase, farnesyl pyrophosphate synthase, fpp synthase, erg20, farnesyl pyrophosphate synthetase, hfpps, farnesyl-diphosphate synthase, fppase, fpps1, fpps3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
farnesyl pyrophosphate synthase
-
-
farnesyl pyrophosphate synthetase
-
-
-
-
farnesyl-diphosphate synthase
-
-
-
-
farnesylpyrophosphate synthetase
-
-
-
-
geranyl transferase I
-
-
-
-
geranyltranstransferase
-
-
-
-
prenyltransferase
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
alkenyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase
Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. The enzyme will not accept larger prenyl diphosphates as efficient donors.
CAS REGISTRY NUMBER
COMMENTARY hide
37277-79-5
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dimethylallyl diphosphate + 2 isopentenyl diphosphate
(E,E)-farnesyl diphosphate + 2 diphosphate
show the reaction diagram
-
-
-
?
geranyl diphosphate + isopentenyl diphosphate
diphosphate + (E,E)-farnesyl diphosphate
show the reaction diagram
-
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
and seed, high expression
Manually annotated by BRENDA team
and stem, low expression
Manually annotated by BRENDA team
hairy root and seed, high expression
Manually annotated by BRENDA team
and leaf, low expression
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
-
reported of the molecular evolution of positive selection sites in plant. Gene expression analysis shows that FPS genes could increase terpenoid accumulation in plants. Large-scale evolutionary analysis of farnesyl diphosphate synthase in land plants. It explores the relationship between the molecular evolution of positive selection sites and their roles in plant farnesyl diphosphate synthase. Farnesyl diphosphate synthase genes in plants appeared very early, and can be traced back to the bryophyte divergence to pteridophyte, which then evolves into gymnospermae, monocotyledonae, and dicotyledoneae. A number of signals for positive selection exist in plant farnesyl diphosphate synthases. Thirty-nine positively selected sites in the site model and three positively selected sites in the branch-site model are detected, respectively
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FPS_PANGI
342
0
39627
Swiss-Prot
other Location (Reliability: 3)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
56000
x * 56000, recombinant protein with tags
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 56000, recombinant protein with tags
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant protein
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
after treatment of hairy root with methyl jasmonate, mRNA is detected within 12 h and achieves a maximum after 24 h
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Kim, O.; Bang, K.; Jung, S.; Kim, Y.; Hyun, D.; Kim, S.; Cha, S.
Molecular characterization of ginseng farnesyl diphosphate synthase gene and its up-regulation by methyl jasmonate
Biol. Plant.
54
47-53
2010
Panax ginseng (Q4JHN6)
-
Manually annotated by BRENDA team
Qian, J.; Liu, Y.; Chao, N.; Ma, C.; Chen, Q.; Sun, J.; Wu, Y.
Positive selection and functional divergence of farnesyl pyrophosphate synthase genes in plants
BMC Mol. Biol.
18
3
2017
Panax ginseng, Eleutherococcus senticosus, Panax quinquefolius, Gynostemma pentaphyllum (A0A076JDS1), Panax notoginseng (Q4TTY7)
Manually annotated by BRENDA team