show all | hide all No of entries

Information on EC 2.4.2.B14 - protein-lysine desuccinylase (NAD+)

for references in articles please use BRENDA:EC2.4.2.B14
preliminary BRENDA-supplied EC number
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.B14 protein-lysine desuccinylase (NAD+)
Specify your search results
Select one or more organisms in this record:
Word Map
The expected taxonomic range for this enzyme is: Archaea, Bacteria, Eukaryota
Synonyms
nicotinamide adenine dinucleotide, sirt5, nad+-dependent protein deacetylase, sirtuin 5, nicotinamide adenine dinucleotide-dependent protein deacetylase, sir2af1, cobb sir2 protein, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
NAD+ + [protein]-N6-acetyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP-ribose
show the reaction diagram
NAD+ + [protein]-N6-succinyl-L-lysine = nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose
show the reaction diagram
Select items on the left to see more content.