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Information on EC 2.4.2.58 - hydroxyproline O-arabinosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.58 hydroxyproline O-arabinosyltransferase
IUBMB Comments
The enzyme, found in plants and mosses, catalyses the O-arabinosylation of hydroxyprolines in hydroxyproline-rich glycoproteins. The enzyme acts on the first hydroxyproline in the motif Val-hydroxyPro-hydroxyPro-Ser.
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Word Map
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
[protein]-trans-4-hydroxy-L-proline
=
+
[protein]-O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-proline
+
[protein]-trans-4-hydroxy-L-proline
=
+
[protein]-trans-4-(beta-L-arabinofuranosyl)oxy-L-proline
Synonyms
plenty, hpat1, hydroxyproline o-arabinosyltransferase, hpat3, hpat2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-beta-L-arabinofuranose + [protein]-trans-4-hydroxy-L-proline = UDP + [protein]-O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-proline
show the reaction diagram
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UDP-beta-L-arabinofuranose + [protein]-trans-4-hydroxy-L-proline = UDP + [protein]-trans-4-(beta-L-arabinofuranosyl)oxy-L-proline
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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