Reference on EC 2.4.2.29 - tRNA-guanosine34 transglycosylase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Okada, N.; Noguchi, S.; Kasai, H.; Shindo-Okada, N.; Ohgi, T.; Goto, T.; Nishimura, S.
Novel mechanism of post-transcriptional modification of tRNA. Insertion of bases of Q precursors into tRNA by a specific tRNA transglycosylase reaction
J. Biol. Chem.
254
3067-3073
1979
Escherichia coli
Manually annotated by BRENDA team
Howes, N.K.; Farkas, W.R.
Studies with a homogeneous enzyme from rabbit erythrocytes catalyzing the insertion of guanine into tRNA
J. Biol. Chem.
253
9082-9087
1978
Oryctolagus cuniculus
Manually annotated by BRENDA team
Gunduz, U.; Kacar, Y.
Transfer -RNA guanine transglycosylase from Salmonella typhimurium
Period. Biol.
90
321-326
1988
Salmonella enterica subsp. enterica serovar Typhimurium
-
Manually annotated by BRENDA team
Garcia, G.A.; Koch, K.A.; Chong, S.
tRNA-guanine transglycosylase from Escherichia coli. Overexpression, purification and quaternary structure
J. Mol. Biol.
231
489-497
1993
Escherichia coli
Manually annotated by BRENDA team
Farkas, W.R.; Jacobson, K.B.; Katze, J.R.
Substrate and inhibitor specificity of tRNA-guanine ribosyltransferase
Biochim. Biophys. Acta
781
64-75
1984
Oryctolagus cuniculus
Manually annotated by BRENDA team
Haumont, E.; Droogmans, L.; Grosjean, H.
Enzymatic formation of queuosine and of glycosyl queuosine in yeast tRNAs microinjected into Xenopus laevis oocytes. The effect of the anticodon loop sequence
Eur. J. Biochem.
168
219-225
1987
Xenopus laevis
Manually annotated by BRENDA team
Walden, T.L.; Howes, N.; Farkas, W.R.
Purification and properties of guanine, queuine-tRNA transglycosylase from wheat germ
J. Biol. Chem.
257
13218-13222
1982
Triticum aestivum
Manually annotated by BRENDA team
Carbon, P.; Haumont, E.; Fournier, M.; de Henau, S.; Grosjean, H.
Site-directed in vitro replacement of nucleosides in the anticodon loop of tRNA: application to the study of structural requirements for queuine insertase activity
EMBO J.
2
1093-1097
1983
Xenopus laevis
Manually annotated by BRENDA team
Shindo-Okada, N.; Okada, N.; Ohgi, T.; Goto, T.; Nishimura, S.
Transfer ribonucleic acid guanine transglycosylase isolated from rat liver
Biochemistry
19
395-400
1980
Rattus norvegicus
Manually annotated by BRENDA team
Kung, F.L.; Garcia, G.A.
tRNA-guanine transglycosylase from Escherichia coli: recognition of full-length 'queuine-cognate' tRNAs
FEBS Lett.
431
427-432
1998
Escherichia coli
Manually annotated by BRENDA team
Romier, C.; Meyer, J.E.W.; Suck, D.
Slight sequence variations of a common fold explain the substrate specificities of tRNA-guanine transglycosylases from the three kingdoms
FEBS Lett.
416
93-98
1997
Caenorhabditis elegans, Haemophilus influenzae, Helicobacter pylori, Homo sapiens, Mus musculus, Shigella flexneri, Synechocystis sp., Thermotoga maritima
Manually annotated by BRENDA team
Brenk, R.; Naerum, L.; Graedler, U.; Gerber, H.D.; Garcia, G.A.; Reuter, K.; Stubbs, M.T.; Klebe, G.
Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis
J. Med. Chem.
46
1133-1143
2003
Shigella flexneri
Manually annotated by BRENDA team
Ishiwata, S.; Katayama, J.; Shindo, H.; Ozawa, Y.; Itoh, K.; Mizugaki, M.
Increased expression of queuosine synthesizing enzyme, tRNA-guanine transglycosylase, and queuosine levels in tRNA of leukemic cells
J. Biochem.
129
13-17
2001
Homo sapiens
Manually annotated by BRENDA team
Romier, C.; Reuter, K.; Suck, D.; Ficner, R.
Crystal structure of tRNA-guanine transglycosylase: RNA modification by base exchange
EMBO J.
15
2850-2857
1996
Zymomonas mobilis
Manually annotated by BRENDA team
Nonekowski, S.T.; Kung, F.L.; Garcia, G.A.
The Escherichia coli tRNA-guanine transglycosylase can recognize and modify DNA
J. Biol. Chem.
277
7178-7182
2002
Escherichia coli, Pyrococcus horikoshii
Manually annotated by BRENDA team
Curnow, A.W.; Garcia, G.A.
tRNA-guanine transglycosylase from Escherichia coli. Minimal tRNA structure and sequence requirements for recognition
J. Biol. Chem.
270
17264-17267
1995
Escherichia coli
Manually annotated by BRENDA team
Kittendorf, J.D.; Barcomb, L.M.; Nonekowski, S.T.; Garcia, G.A.
tRNA-guanine transglycosylase from Escherichia coli: Molecular mechanism and role of aspartate 89
Biochemistry
40
14123-14133
2001
Escherichia coli
Manually annotated by BRENDA team
Reuter, K.; Chong, S.; Ullrich, F.; Kersten, H.; Garcia, G.A.
Serine 90 is required for enzymic activity by tRNA-guanine transglycosylase from Escherichia coli
Biochemistry
33
7041-7046
1994
Escherichia coli
Manually annotated by BRENDA team
Hoops, G.C.; Townsend, L.B.; Garcia, G.A.
Mechanism-based inactivation of tRNA-guanine transglycosylase from Escherichia coli by 2-amino-5-(fluoromethyl)pyrrolo[2,3-d]pyrimidin-4(3H)-one
Biochemistry
34
15539-15544
1995
Escherichia coli
Manually annotated by BRENDA team
Deshpande, K.L.; Seubert, P.H.; Tillman, D.M.; Farkas, W.R.; Katze, J.R.
Cloning and characterization of cDNA encoding the rabbit tRNA-guanine transglycosylase 60-kilodalton subunit
Arch. Biochem. Biophys.
326
1-7
1996
Oryctolagus cuniculus
Manually annotated by BRENDA team
Nonekowski, S.T.; Garcia, G.A.
tRNA recognition by tRNA-guanine transglycosylase from escherichia coli: the role of U33 in U-G-U sequence recognition
RNA
7
1432-1441
2001
Escherichia coli
Manually annotated by BRENDA team
Kung, F.L.; Nonekowski, S.; Garcia, G.A.
tRNA-guanine transglycosylase from Escherichia coli: recognition of noncognate-cognate chimeric tRNA and discovery of a novel recognition site within the TyC arm of tRNAPhe
RNA
6
233-244
2000
Escherichia coli
Manually annotated by BRENDA team
Goodenough-Lashua, D.M.; Garcia, G.A.
tRNA-guanine transglycosylase from E. coli: a ping-pong kinetic mechanism is consistent with nucleophilic catalysis
Bioorg. Chem.
31
331-344
2003
Escherichia coli, Shigella flexneri
Manually annotated by BRENDA team
Kittendorf, J.D.; Sgraja, T.; Reuter, K.; Klebe, G.; Garcia, G.A.
An essential role for aspartate 264 in catalysis by tRNA-guanine transglycosylase from Escherichia coli
J. Biol. Chem.
278
42369-42376
2003
Escherichia coli, Zymomonas mobilis
Manually annotated by BRENDA team
Todorov, K.A.; Tan, X.J.; Nonekowski, S.T.; Garcia, G.A.; Carlson, H.A.
The role of aspartic acid 143 in E. coli tRNA-guanine transglycosylase: insights from mutagenesis studies and computational modeling
Biophys. J.
89
1965-1977
2005
Escherichia coli
Manually annotated by BRENDA team
Ishiwata, S.; Ozawa, Y.; Katayama, J.; Kaneko, S.; Shindo, H.; Tomioka, Y.; Ishiwata, T.; Asano, G.; Ikegawa, S.; Mizugaki, M.
Elevated expression level of 60-kDa subunit of tRNA-guanine transglycosylase in colon cancer
Cancer Lett.
212
113-119
2004
Homo sapiens
Manually annotated by BRENDA team
Brenk, R.; Stubbs, M.T.; Heine, A.; Reuter, K.; Klebe, G.
Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design
ChemBioChem
4
1066-1077
2003
Zymomonas mobilis (P28720), Zymomonas mobilis
Manually annotated by BRENDA team
Todorov, K.A.; Garcia, G.A.
Role of aspartate 143 in Escherichia coli tRNA-guanine transglycosylase: alteration of heterocyclic substrate specificity
Biochemistry
45
617-625
2006
Escherichia coli
Manually annotated by BRENDA team
Stengl, B.; Reuter, K.; Klebe, G.
Mechanism and substrate specificity of tRNA-guanine transglycosylases (TGTs): tRNA-modifying enzymes from the three different kingdoms of life share a common catalytic mechanism
Chembiochem
6
1926-1939
2005
Escherichia coli, Homo sapiens, Schizosaccharomyces pombe, Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Meyer, E.A.; Donati, N.; Guillot, M.; Schweizer, W.B.; Diederich, F.; Stengl, B.; Brenk, R.; Reuter, K.; Klebe, G.
Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-guanine transglycosylase (TGT)
Helv. Chim. Acta
89
573-597
2006
Zymomonas mobilis
-
Manually annotated by BRENDA team
Stengl, B.; Meyer, E.A.; Heine, A.; Brenk, R.; Diederich, F.; Klebe, G.
Crystal structures of tRNA-guanine transglycosylase (TGT) in complex with novel and potent inhibitors unravel pronounced induced-fit adaptations and suggest dimer formation upon substrate binding
J. Mol. Biol.
370
492-511
2007
Zymomonas mobilis (P28720), Zymomonas mobilis
Manually annotated by BRENDA team
Hoertner, S.R.; Ritschel, T.; Stengl, B.; Kramer, C.; Schweizer, W.B.; Wagner, B.; Kansy, M.; Klebe, G.; Diederich, F.
Potent inhibitors of tRNA-guanine transglycosylase, an enzyme linked to the pathogenicity of the Shigella bacterium: charge-assisted hydrogen bonding
Angew. Chem.
46
8266-8269
2007
Shigella flexneri (Q54177)
Manually annotated by BRENDA team
Tidten, N.; Stengl, B.; Heine, A.; Garcia, G.A.; Klebe, G.; Reuter, K.
Glutamate versus glutamine exchange swaps substrate selectivity in tRNA-guanine transglycosylase: insight into the regulation of substrate selectivity by kinetic and crystallographic studies
J. Mol. Biol.
374
764-776
2007
Zymomonas mobilis (P28720), Zymomonas mobilis
Manually annotated by BRENDA team
Hurt, J.K.; Olgen, S.; Garcia, G.A.
Site-specific modification of Shigella flexneri virF mRNA by tRNA-guanine transglycosylase in vitro
Nucleic Acids Res.
35
4905-4913
2007
Escherichia coli, Escherichia coli (P0A847)
Manually annotated by BRENDA team
Garcia, G.A.; Chervin, S.M.; Kittendorf, J.D.
Identification of the rate-determining step of tRNA-guanine transglycosylase from Escherichia coli
Biochemistry
48
11243-11251
2009
Escherichia coli
Manually annotated by BRENDA team
Ritschel, T.; Hoertner, S.; Heine, A.; Diederich, F.; Klebe, G.
Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT
ChemBioChem
10
716-727
2009
Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Kohler, P.C.; Ritschel, T.; Schweizer, W.B.; Klebe, G.; Diederich, F.
High-affinity inhibitors of tRNA-guanine transglycosylase replacing the function of a structural water cluster
Chemistry
15
10809-10817
2009
Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Ritschel, T.; Kohler, P.C.; Neudert, G.; Heine, A.; Diederich, F.; Klebe, G.
How to replace the residual solvation shell of polar active site residues to achieve nanomolar inhibition of tRNA-guanine transglycosylase
ChemMedChem
4
2012-2023
2009
Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Ritschel, T.; Atmanene, C.; Reuter, K.; Van Dorsselaer, A.; Sanglier-Cianferani, S.; Klebe, G.
An integrative approach combining noncovalent mass spectrometry, enzyme kinetics and X-ray crystallography to decipher Tgt protein-protein and protein-RNA interaction
J. Mol. Biol.
393
833-847
2009
Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Chen, Y.C.; Kelly, V.P.; Stachura, S.V.; Garcia, G.A.
Characterization of the human tRNA-guanine transglycosylase: Confirmation of the heterodimeric subunit structure
RNA
16
958-968
2010
Homo sapiens, Homo sapiens (Q9BXR0)
Manually annotated by BRENDA team
Eric Thomas, C.; Chen, Y.C.; Garcia, G.A.
Differential heterocyclic substrate recognition by, and pteridine inhibition of E. coli and human tRNA-guanine transglycosylases
Biochem. Biophys. Res. Commun.
410
34-39
2011
Escherichia coli, Homo sapiens, Homo sapiens (Q9BXR0)
Manually annotated by BRENDA team
Barandun, L.J.; Immekus, F.; Kohler, P.C.; Tonazzi, S.; Wagner, B.; Wendelspiess, S.; Ritschel, T.; Heine, A.; Kansy, M.; Klebe, G.; Diederich, F.
From lin-benzoguanines to lin-benzohypoxanthines as ligands for Zymomonas mobilis tRNA-guanine transglycosylase: replacement of protein-ligand hydrogen bonding by importing water clusters
Chemistry
18
9246-9257
2012
Zymomonas mobilis (P28720), Zymomonas mobilis
Manually annotated by BRENDA team
Nomura, Y.; Onda, Y.; Ohno, S.; Taniguchi, H.; Ando, K.; Oka, N.; Nishikawa, K.; Yokogawa, T.
Purification and comparison of native and recombinant tRNA-guanine transglycosylases from Methanosarcina acetivorans
Protein Expr. Purif.
88
13-19
2013
Methanosarcina acetivorans, Methanosarcina acetivorans (Q8THU2 and Q8TUE6), Methanosarcina acetivorans DSM 2834 (Q8THU2 and Q8TUE6)
Manually annotated by BRENDA team
Barandun, L.J.; Immekus, F.; Kohler, P.C.; Ritschel, T.; Heine, A.; Orlando, P.; Klebe, G.; Diederich, F.
High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization
Acta Crystallogr. Sect. D
69
1798-1807
2013
Zymomonas mobilis (P28720), Zymomonas mobilis
Manually annotated by BRENDA team
Barandun, L.J.; Ehrmann, F.R.; Zimmerli, D.; Immekus, F.; Giroud, M.; Gruenenfelder, C.; Schweizer, W.B.; Bernet, B.; Betz, M.; Heine, A.; Klebe, G.; Diederich, F.
Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT)
Chemistry
21
126-135
2015
Zymomonas mobilis (P28720)
Manually annotated by BRENDA team
Sawhney, B.; Chopra, K.; Misra, R.; Ranjan, A.
Identification of Plasmodium falciparum apicoplast-targeted tRNA-guanine transglycosylase and its potential inhibitors using comparative genomics, molecular modelling, docking and simulation studies
J. Biomol. Struct. Dyn.
33
2404-2420
2015
Plasmodium falciparum
Manually annotated by BRENDA team