Reference on EC 2.4.2.12 - nicotinamide phosphoribosyltransferase and Organism(s) Mus musculus and UniProt Accession Q99KQ4
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Rongvaux, A.; Shea, R.J.; Mulks, M.H.; Gigot, D.; Urbain, J.; Leo, O.; Andris, F.
Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis
Eur. J. Immunol.
32
3225-3234
2002
Mus musculus
Revollo, J.R.; Grimm, A.A.; Imai, S.
The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
J. Biol. Chem.
279
50754-50763
2004
Mus musculus (Q99KQ4), Mus musculus
Khan, J.A.; Tao, X.; Tong, L.
Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents
Nat. Struct. Mol. Biol.
13
582-588
2006
Homo sapiens (P43490), Homo sapiens, Mus musculus (Q99KQ4), Mus musculus
Busso, N.; Karababa, M.; Nobile, M.; Rolaz, A.; Van Gool, F.; Galli, M.; Leo, O.; So, A.; De Smedt, T.
Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD
PLoS ONE
3
e2267
2008
Homo sapiens (P43490), Mus musculus (Q99KQ4)
Beauparlant, P.; Bedard, D.; Bernier, C.; Chan, H.; Gilbert, K.; Goulet, D.; Gratton, M.O.; Lavoie, M.; Roulston, A.; Turcotte, E.; Watson, M.
Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777
Anticancer Drugs
20
346-354
2009
Homo sapiens, Mus musculus
Hsu, C.P.; Oka, S.; Shao, D.; Hariharan, N.; Sadoshima, J.
Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes
Circ. Res.
105
481-491
2009
Mus musculus
Zhang, R.Y.; Qin, Y.; Lv, X.Q.; Wang, P.; Xu, T.Y.; Zhang, L.; Miao, C.Y.
A fluorometric assay for high-throughput screening targeting nicotinamide phosphoribosyltransferase
Anal. Biochem.
412
18-25
2011
Mus musculus
Liu, L.; Wang, F.; Zhang, X.; Huang, P.; Lu, Y.; Wei, E.; Zhang, W.
Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases
PLoS ONE
7
e44933
2012
Mus musculus
Pittelli, M.; Cavone, L.; Lapucci, A.; Oteri, C.; Felici, R.; Niccolai, E.; Amedei, A.; Chiarugi, A.
Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes
Immunol. Cell Biol.
92
191-199
2014
Mus musculus, Homo sapiens (P43490), Homo sapiens
Molugu, T.R.; Oita, R.C.; Chawla, U.; Camp, S.M.; Brown, M.F.; Garcia, J.G.N.
Nicotinamide phosphoribosyltransferase purification using SUMO expression system
Anal. Biochem.
598
113597
2020
Mus musculus (Q99KQ4)
Zhang, L.Q.; Van Haandel, L.; Xiong, M.; Huang, P.; Heruth, D.P.; Bi, C.; Gaedigk, R.; Jiang, X.; Li, D.Y.; Wyckoff, G.; Grigoryev, D.N.; Gao, L.; Li, L.; Wu, M.; Leeder, J.S.; Ye, S.Q.
Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
Cell Death Dis.
8
e2705
2017
Mus musculus (Q99KQ4), Mus musculus
Torretta, S.; Colombo, G.; Travelli, C.; Boumya, S.; Lim, D.; Genazzani, A.A.; Grolla, A.A.
The cytokine nicotinamide phosphoribosyltransferase (eNAMPT; PBEF; visfatin) acts as a natural antagonist of C-C chemokine receptor type 5 (CCR5)
Cells
9
496
2020
Homo sapiens (P43490), Mus musculus (Q99KQ4)
Kong, J.; Du, C.; Jiang, L.; Jiang, W.; Deng, P.; Shao, X.; Zhang, B.; Li, Y.; Zhu, R.; Zhao, Q.; Fu, D.; Gu, H.; Luo, L.; Long, H.; Zhao, Y.; Cen, X.
Nicotinamide phosphoribosyltransferase regulates cocaine reward through sirtuin 1
Exp. Neurol.
307
52-61
2018
Mus musculus (Q99KQ4)
Feng, D.; Xu, D.; Murakoshi, N.; Tajiri, K.; Qin, R.; Yonebayashi, S.; Okabe, Y.; Li, S.; Yuan, Z.; Aonuma, K.; Ieda, M.
Nicotinamide phosphoribosyltransferase (Nampt)/nicotinamide adenine dinucleotide (NAD) axis suppresses atrial fibrillation by modulating the calcium handling pathway
Int. J. Mol. Sci.
21
4655
2020
Mus musculus (Q99KQ4)
Svoboda, P.; Krizova, E.; Sestakova, S.; Vapenkova, K.; Knejzlik, Z.; Rimpelova, S.; Rayova, D.; Volfova, N.; Krizova, I.; Rumlova, M.; Sykora, D.; Kizek, R.; Haluzik, M.; Zidek, V.; Zidkova, J.; Skop, V.
Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle-dependent in mammalian cells, and its inhibition slows cell growth
J. Biol. Chem.
294
8676-8689
2019
Homo sapiens (P43490), Mus musculus (Q99KQ4)
Travelli, C.; Aprile, S.; Rahimian, R.; Grolla, A.A.; Rogati, F.; Bertolotti, M.; Malagnino, F.; di Paola, R.; Impellizzeri, D.; Fusco, R.; Mercalli, V.; Massarotti, A.; Stortini, G.; Terrazzino, S.; Del Grosso, E.; Fakhfouri, G.; Troiani, M.P.; Alisi, M.A.; Grosa, G.; Sorba, G.; Canonico, P.L.; Orsomando, G.
Identification of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors endowed with antiproliferative and antiinflammatory activity
J. Med. Chem.
60
1768-1792
2017
Mus musculus (Q99KQ4)
Hara, N.; Osago, H.; Hiyoshi, M.; Kobayashi-Miura, M.; Tsuchiya, M.
Quantitative analysis of the effects of nicotinamide phosphoribosyltransferase induction on the rates of NAD+ synthesis and breakdown in mammalian cells using stable isotope-labeling combined with mass spectrometry
PLoS ONE
14
e0214000
2019
Homo sapiens (P43490), Rattus norvegicus (Q80Z29), Mus musculus (Q99KQ4)
