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5'-nucleotidase deficiency
Inborn errors of purine metabolism: clinical update and therapies.
Abnormalities, Multiple
The effect of polyneuropathy on foot microcirculation in Type II diabetes.
Acantholysis
Ectopic expression of epidermal antigens renders the lung a target organ in paraneoplastic pemphigus.
Acantholysis
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Acantholysis
Sensitivity and specificity of clinical, histologic, and immunologic features in the diagnosis of paraneoplastic pemphigus.
Acantholysis
[Basic and clinical research on paraneoplastic pemphigus]
Acquired Immunodeficiency Syndrome
A DEAD-box RNA helicase in the Escherichia coli RNA degradosome.
Acquired Immunodeficiency Syndrome
Activities of purine metabolising enzymes in lymphocytes of neonates and young children: correlates with immune function.
Acquired Immunodeficiency Syndrome
Elevated adenosine deaminase and purine nucleoside phosphorylase activity in peripheral blood null lymphocytes from patients with acquired immune deficiency syndrome.
Acquired Immunodeficiency Syndrome
Elevated erythrocyte adenosine deaminase activity in patients with acquired immunodeficiency syndrome.
Acquired Immunodeficiency Syndrome
In vitro modulation of purine enzyme metabolism and lymphocyte surface marker expression by thymosin fraction 5 in homosexual males.
Acquired Immunodeficiency Syndrome
Potentiating effect of (2-[2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methyl]-phenyl]ethenyl) -phosphonic acid (MDL 74,428), a potent inhibitor of purine nucleoside phosphorylase, on the antiretroviral activities of 2',3'-dideoxyinosine combined with ribavirin in mice.
Acquired Immunodeficiency Syndrome
Predictive variables for peripheral neuropathy in treated HIV type 1 infection revealed by machine learning.
Activated Protein C Resistance
Homozygous factor V-deficient patients show resistance to activated protein C whereas heterozygotes do not.
adenine phosphoribosyltransferase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
adenine phosphoribosyltransferase deficiency
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Adenocarcinoma
Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine.
Adenocarcinoma
Metabolites of Purine Nucleoside Phosphorylase (NP) in Serum Have the Potential to Delineate Pancreatic Adenocarcinoma.
Adenocarcinoma
Paraneoplastic pemphigus without antidesmoglein 3 or antidesmoglein 1 autoantibodies.
Adenocarcinoma
Suicide gene/prodrug therapy for pancreatic adenocarcinoma by E. coli purine nucleoside phosphorylase and 6-methylpurine 2'-deoxyriboside.
adenosine deaminase deficiency
Absence of oroticaciduria in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency.
adenosine deaminase deficiency
Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency.
adenosine deaminase deficiency
Disorders of purine and pyrimidine metabolism.
adenosine deaminase deficiency
Evidence that X-linked severe combined immunodeficiency is not a differentiation defect of T lymphocytes.
adenosine deaminase deficiency
Immunodeficiency disease in animals.
adenosine deaminase deficiency
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).
adenosine deaminase deficiency
Nucleoside kinases in T and B lymphoblasts distinguished by autoradiography.
adenosine deaminase deficiency
Polyethylene glycol-conjugated adenosine phosphorylase: development of alternative enzyme therapy for adenosine deaminase deficiency.
adenosine deaminase deficiency
Polymorphism of S-adenosylhomocysteine hydrolase in Italy.
adenosine deaminase deficiency
Purine nucleoside modulation of functions of human lymphocytes.
adenosine deaminase deficiency
Screening for primary immunodeficiencies associated with purine nucleoside phosphorylase deficiency or adenosine deaminase deficiency.
adenosine deaminase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
adenosylhomocysteinase deficiency
Proposed explanation for S-adenosylhomocysteine hydrolase deficiency in purine nucleoside phosphorylase and hypoxanthine-guanine phosphoribosyltransferase-deficient patients.
adenylosuccinate lyase deficiency
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
adenylosuccinate lyase deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
adenylosuccinate lyase deficiency
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Agammaglobulinemia
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
Albuminuria
Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis.
Alopecia
[Mechanism of alopecia in patients with paraneoplastic pemphigus]
Alzheimer Disease
Purine-related metabolites and their converting enzymes are altered in frontal, parietal and temporal cortex at early stages of Alzheimer's disease pathology.
Alzheimer Disease
The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients.
amidase deficiency
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Amyloidosis
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Anemia
Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.
Anemia
Purine nucleoside phosphorylase activity of human erythrocytes in iron deficiency anaemia.
Anemia, Hemolytic
Erythrocyte GTP depletion in PNP deficiency presenting with haemolytic anaemia and hypouricaemia.
Anemia, Hemolytic, Autoimmune
Cellular immune deficiency with autoimmune hemolytic anemia in purine nucleoside phosphorylase deficiency.
Anemia, Hemolytic, Autoimmune
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.
Anemia, Hypochromic
Chloroplast-to-nucleus retrograde signalling controls intercellular trafficking via plasmodesmata formation.
Anemia, Iron-Deficiency
Purine nucleoside phosphorylase activity of human erythrocytes in iron deficiency anaemia.
Apnea
Purine nucleoside phosphorylase and xanthine oxidase activities in erythrocytes and plasma from marine, semiaquatic and terrestrial mammals.
Argininosuccinic Aciduria
Direct-infusion based metabolomics unveils biochemical profiles of inborn errors of metabolism in cerebrospinal fluid.
Arrhythmias, Cardiac
[Chemotherapy of advanced non-small-cell and small-cell bronchial carcinoma with bendamustine--a phase II study]
Arthritis
An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome.
Arthritis, Juvenile
An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome.
Arthritis, Rheumatoid
Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues.
Arthritis, Rheumatoid
Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
Arthritis, Rheumatoid
Purine enzyme activities in recent onset rheumatoid arthritis: are there differences between patients and healthy controls?
Arthritis, Rheumatoid
Purine enzyme levels in rheumatoid arthritis.
Asthma
Determination of plasma purine nucleoside phosphorylase activity by high-performance liquid chromatography.
Asthma
Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries.
Ataxia
Novel Genetic Mutations in the First Swedish Patient with Purine Nucleoside Phosphorylase Deficiency and Clinical Outcome After Hematopoietic Stem Cell Transplantation with HLA-Matched Unrelated Donor.
Ataxia
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.
Ataxia
Successful HLA-identical bone marrow transplantation in a patient with PNP deficiency using busulfan and fludarabine for conditioning.
Ataxia
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.
Ataxia
The correlation of adenosine deaminase and purine nucleoside phosphorylase activities in human lymphocytes subpopulations and in various lymphoid malignancies.
Ataxia Telangiectasia
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies.
Ataxia Telangiectasia
Partial Purine Nucleoside Phosphorylase Deficiency Helps Determine Minimal Activity Required for Immune and Neurological Development.
Ataxia Telangiectasia
Primary immunodeficiency diseases associated with neurologic manifestations.
Atherosclerosis
Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE-/-) mice.
Atherosclerosis
Role of parnaparin in atherosclerosis.
Atherosclerosis
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.
Atrial Fibrillation
Long-term course of phrenic nerve injury after cryoballoon ablation of atrial fibrillation.
Atrial Fibrillation
The 'single big cryoballoon' technique for acute pulmonary vein isolation in patients with paroxysmal atrial fibrillation: a prospective observational single centre study.
Autoimmune Diseases
9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.
Autoimmune Diseases
Autoimmunity against desmosomal cadherins in pemphigus.
Autoimmune Diseases
cDNA cloning of the 210-kDa paraneoplastic pemphigus antigen reveals that envoplakin is a component of the antigen complex.
Autoimmune Diseases
Discovery of a Novel Inhibitor of Human Purine Nucleoside Phosphorylase by a Simple Hydrophilic Interaction Liquid Chromatography Enzymatic Assay.
Autoimmune Diseases
Human autoantibodies against HD1/plectin in paraneoplastic pemphigus.
Autoimmune Diseases
Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange.
Autoimmune Diseases
Immunoablative high-dose cyclophosphamide without stem cell rescue in paraneoplastic pemphigus: report of a case and review of this new therapy for severe autoimmune disease.
Autoimmune Diseases
Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
Autoimmune Diseases
Paraneoplastic Pemphigus with Underlying Retroperitoneal Inflammatory Myofibroblastic Tumor: A Case Report and Review of the Literature.
Autoimmune Diseases
Paraneoplastic pemphigus: a case of long-term survival associated with systemic lupus erythematosus and polymyositis.
Autoimmune Diseases
Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes-A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.
Autoimmune Diseases
Purine nucleoside phosphorylase deficiency with fatal course in two sisters.
Autoimmune Diseases
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.
Autoimmune Diseases
Pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase (PNP) inhibitors as potential T-cell selective immunosuppressive agents.
Autoimmune Diseases
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
Autoimmune Diseases
Structure-based design of inhibitors of purine nucleoside phosphorylase.
Bacterial Infections
Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries.
Beriberi
Subclinical beriberi polyneuropathy in the low income group: an investigation with special tools on possible patients with suspected complaints.
Blast Crisis
5'nucleotidase, adenosine deaminase and purine nucleoside phosphorylase activities in acute leukaemia.
Blast Crisis
Differential expression of adenosine deaminase isozymes in acute leukemia.
Blast Crisis
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
Blast Crisis
[Enzymatic markers in chronic myeloleukemia and their importance for identifying a blast crisis]
Blast Crisis
[Thymidine kinase activity in leukocytes from patients with chronic myeloid leukemia at various periods in the disease]
Blister
Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice.
Blister
Clinical phenotype and anti-desmoglein autoantibody profile in paraneoplastic pemphigus.
Blister
Intra-abdominal inflammatory pseudotumor-like follicular dendritic cell sarcoma associated with paraneoplastic pemphigus: A case report and review of the literature.
Blister
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Blister
Pathogenic Anti-Desmoglein 3 mAbs Cloned from a Paraneoplastic Pemphigus Patient by Phage Display.
Blister
Rituximab Monotherapy and Rituximab-Containing Chemotherapy Were Effective for Paraneoplastic Pemphigus Accompanying Follicular Lymphoma, but not for Subsequent Bronchiolitis Obliterans.
Breast Neoplasms
Douleur Neuropathique 4 (DN4) stratifies possible and definite neuropathic pain after surgical peripheral nerve lesion.
Breast Neoplasms
Neoplasms associated with paraneoplastic pemphigus: a review with emphasis on non-hematologic malignancy and oral mucosal manifestations.
Breast Neoplasms
Nuclear EGFR Suppresses Ribonuclease Activity of Polynucleotide Phosphorylase through DNAPK-mediated Phosphorylation at Serine 776.
Breast Neoplasms
Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy.
Breast Neoplasms
Purine salvage enzyme activities in normal and neoplastic human tissues.
Breast Neoplasms
Suicide gene therapy-mediated purine nucleoside phosphorylase/fludarabine system for in vitro breast cancer model with emphasis on evaluation of vascular endothelial growth factor promoter efficacy.
Breast Neoplasms
[Development of a conceptual model for interpretation of monitoring indicators of cancer screenings from the Italian National Prevention Plan].
Bronchiolitis
Clinical Analysis of Unicentric Castleman's Disease with Paraneoplastic Pemphigus and Bronchiolitis Obliterans.
Bronchiolitis
Epiplakin is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients.
Bronchiolitis Obliterans
A middle-aged man presenting with unexplained mucosal erosions and progressive dyspnoea.
Bronchiolitis Obliterans
Achievement of the longest survival of paraneoplastic pemphigus with bronchiolitis obliterans associated with follicular lymphoma using R-CHOP chemotherapy.
Bronchiolitis Obliterans
Epiplakin is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients.
Bronchiolitis Obliterans
Epiplakin Is a Paraneoplastic Pemphigus Autoantigen and Related to Bronchiolitis Obliterans in Japanese Patients.
Bronchiolitis Obliterans
Extremities of the N-terminus of envoplakin and C-terminus of its linker subdomain are major epitopes of paraneoplastic pemphigus.
Bronchiolitis Obliterans
No involvement of IgG autoantibodies against extracellular domains of desmoglein 2 in paraneoplastic pemphigus or inflammatory bowel diseases.
Bronchiolitis Obliterans
Paraneoplastic Pemphigus and Bronchiolitis Obliterans in a Patient with Splenic B-cell Lymphoma.
Bronchiolitis Obliterans
Paraneoplastic pemphigus associated with bronchiolitis obliterans.
Bronchiolitis Obliterans
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Bronchiolitis Obliterans
Paraneoplastic Pemphigus Involving the Respiratory and Gastrointestinal Mucosae.
Bronchiolitis Obliterans
Paraneoplastic pemphigus.
Bronchiolitis Obliterans
Paraneoplastic Pemphigus: Paraneoplastic Autoimmune Disease of the Skin and Mucosa.
Bronchiolitis Obliterans
Retrospective analysis of 45 cases of localized retroperitoneal Castleman disease from a single center.
Bronchiolitis Obliterans
Risk factors for death and survival in paraneoplastic pemphigus associated with hematologic malignancies in adults.
Bronchiolitis Obliterans
Successful treatment of a paraneoplastic pemphigus in a teenager using plasmapheresis, corticosteroids and tumour resection.
Bronchiolitis Obliterans
[Localized Castleman disease with paraneoplastic pemphigus and pulmonary involvement: clinical features and histopathology]
Bronchiolitis Obliterans
[Surgical treatment and prognosis analysis of localized retroperitoneal Castleman disease: a study of 20 cases.]
Bronchitis
Clinical role of gasless laparoscopic adrenalectomy.
Burkitt Lymphoma
Multienzymatic analyses of human malignant lymphomas. Correlation of enzymatic data with pathologic and ultrastructural findings in Burkitt's and lymphoblastic lymphomas.
Carcinogenesis
Incorporation of extracellular 8-oxodG into DNA and RNA requires purine nucleoside phosphorylase in MCF-7 cells.
Carcinoma
A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration.
Carcinoma
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral blood cells of patients with neoplastic diseases. I. Bronchogenic carcinoma.
Carcinoma
Characterization of paraneoplastic pemphigus autoantigens by immunoblot analysis.
Carcinoma
Characterization of the metabolism of perinecrotic cells in solid tumors by enzyme histochemistry.
Carcinoma
Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine.
Carcinoma
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Carcinoma
Oral presentation of paraneoplastic pemphigus as the first sign of tonsillar HPV associated squamous cell carcinoma. A case report.
Carcinoma
Paraneoplastic pemphigus associated with uterine carcinoma.
Carcinoma
Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation.
Carcinoma
Purine metabolizing enzymes in lymphocytes from patients with solid tumors.
Carcinoma
Studies on purine enzymes in experimental colitis.
Carcinoma
Suicide gene/prodrug therapy using salmonella-mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6-methoxypurine 2'-deoxyriboside in murine mammary carcinoma 4T1 model.
Carcinoma
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Carcinoma
Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy.
Carcinoma
Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines.
Carcinoma, Bronchogenic
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral blood cells of patients with neoplastic diseases. I. Bronchogenic carcinoma.
Carcinoma, Bronchogenic
Purine metabolizing enzymes in lymphocytes from patients with solid tumors.
Carcinoma, Ehrlich Tumor
Separation and modification of the phosphorolytic and ribosyl transfer activities of the purine nucleoside phosphorylase of Ehrlich ascites tumor cells.
Carcinoma, Hepatocellular
An ultrasonic nanobubble-mediated PNP/fludarabine suicide gene system: A new approach for the treatment of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Behavior of inosine phosphorylase (EC 2.4.2.1) activity in normal, differentiating, and regenerating liver and in hepatomas.
Carcinoma, Hepatocellular
Evidence for a trans-dominant regulator of purine nucleoside phosphorylase expression in rat hepatoma cells.
Carcinoma, Hepatocellular
Experimental studies on PNP suicide gene therapy of hepatoma.
Carcinoma, Hepatocellular
Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene.
Carcinoma, Hepatocellular
Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro.
Carcinoma, Hepatocellular
Paraneoplastic pemphigus in association with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Some biochemical mechanisms underlying the impairment of T and B cell immunity in C3HA mice during hepatoma growth.
Carcinoma, Hepatocellular
[Biochemical and functional characteristics of thymus and spleen lymphocytes in C3HA mice during the growth of hepatoma 22 and after immunization with sheep erythrocytes]
Carcinoma, Hepatocellular
[Changes in DNA and purine nucleotide synthesis in lymphoid cells and sensitivity to glucocorticoids associated with the impairment of differentiation and immune function in mice during tumor growth. Spleen T- and B-lymphocytes]
Carcinoma, Hepatocellular
[Changes in purine metabolism and in the immune response in the thymic and splenic lymphocytes of C3HA mice during chemical hepatocarcinogenesis]
Carcinoma, Hepatocellular
[The activity of polynucleotide phosphorylase in polyribosomes of regenerating liver of adult rats, liver of newborn rats and in some reinoculated tumours]
Carcinoma, Renal Cell
Pemphigus in Sarcomatoid Renal Cell Carcinoma: A Rare Paraneoplastic Manifestation.
Carcinoma, Squamous Cell
Characterization of paraneoplastic pemphigus autoantigens by immunoblot analysis.
Carcinoma, Squamous Cell
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Carcinoma, Squamous Cell
Oral presentation of paraneoplastic pemphigus as the first sign of tonsillar HPV associated squamous cell carcinoma. A case report.
Carcinoma, Squamous Cell
Simultaneous assay of adenosine deaminase and purine nucleoside phosphorylase activity as possible biochemical means to detect non-Hodgkin lymphomas of the oral cavity.
Carcinoma, Squamous Cell
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Cardiac Tamponade
Cryoballoon versus radiofrequency ablation for persistent atrial fibrillation: a systematic review and meta?analysis.
Carotid Artery Diseases
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.
Carpal Tunnel Syndrome
Clinical and nerve conduction studies in female patients with diabetic dermopathy.
Carpal Tunnel Syndrome
Ulnar Neuropathy at Elbow in Patients With Type 2 Diabetes Mellitus.
Castleman Disease
A case of paraneoplastic pemphigus associated with Castleman's disease presenting as erosive lichen planus.
Castleman Disease
A case of paraneoplastic pemphigus associated with Castleman's disease.
Castleman Disease
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus.
Castleman Disease
Castleman's Disease with Paraneoplastic Pemphigus.
Castleman Disease
Childhood paraneoplastic pemphigus associated with Castleman's tumour.
Castleman Disease
Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.
Castleman Disease
Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature.
Castleman Disease
Imaging characteristics of abdominal tumor in association with paraneoplastic pemphigus.
Castleman Disease
Masked pemphigus among pediatric patients with Castleman's disease.
Castleman Disease
Multidisciplinary diagnosis and treatment of recurrent follicular dendritic cell sarcoma in abdomen: A case report.
Castleman Disease
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Castleman Disease
Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma arising from Castleman's tumor.
Castleman Disease
Paraneoplastic pemphigus in association with Castleman's disease.
Castleman Disease
Paraneoplastic pemphigus in children and adolescents.
Castleman Disease
Paraneoplastic pemphigus.
Castleman Disease
Retroperitoneal Castleman's tumor and paraneoplastic pemphigus: report of a case and review of the literature.
Castleman Disease
Successful treatment of a paraneoplastic pemphigus in a teenager using plasmapheresis, corticosteroids and tumour resection.
Castleman Disease
The role of pathogenic B-cell clones in antibody mediated autoimmune disorders.
Castleman Disease
[Clinical features and surgical treatment of thoracic Castleman's disease.]
Castleman Disease
[Localized Castleman disease with paraneoplastic pemphigus and pulmonary involvement: clinical features and histopathology]
Castleman Disease
[Treatment of paraneoplastic pemphigus with Castleman's disease]
Cerebral Palsy
A new case of purine nucleoside phosphorylase deficiency: enzymologic, clinical, and immunologic characteristics.
Cerebrovascular Disorders
Stroke in purine nucleoside phosphorylase deficiency.
Chagas Disease
Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity.
Charcot-Marie-Tooth Disease
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Charcot-Marie-Tooth Disease
Association between restless legs syndrome and peripheral neuropathy: A systematic review and meta-analysis.
Charcot-Marie-Tooth Disease
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).
Chickenpox
Normal uric acid concentrations in a purine nucleoside phosphorylase (PNP) deficient child presenting with severe chicken pox, possible immunodeficiency and developmental delay.
Chickenpox
Varicella exposure in a child at risk of being immunosuppressed.
Cholangitis, Sclerosing
Sclerosing cholangitis and combination antifungal therapy for PNP deficiency patients.
Cholera
Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles.
Coinfection
Chronic lymphocytic leukemia-associated paraneoplastic pemphigus: potential cause and therapeutic strategies.
Coinfection
Detection of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, swine influenza virus and Aujeszky's disease virus in cases of porcine proliferative and necrotizing pneumonia (PNP) in Spain.
Colonic Neoplasms
Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells.
Colorectal Neoplasms
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer.
Coma
Polynucleotide phosphorylase is necessary for competence development in Bacillus subtilis.
Common Variable Immunodeficiency
Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency.
Common Variable Immunodeficiency
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies.
Conjunctivitis
Intra-abdominal inflammatory pseudotumor-like follicular dendritic cell sarcoma associated with paraneoplastic pemphigus: A case report and review of the literature.
Conjunctivitis
Recurrent corneal melting in the paraneoplastic pemphigus associated with Castleman's disease.
Corneal Perforation
Bilateral corneal melting in a patient with paraneoplastic pemphigus.
Corneal Perforation
Paraneoplastic Pemphigus Associated with Bilateral Corneal Perforations in Follicular Dendritic Cell Sarcoma.
Corneal Perforation
Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report.
Crohn Disease
Effects of Mesalazine on Morphological and Functional Changes in the Indomethacin-Induced Inflammatory Bowel Disease (Rat Model of Crohn's Disease).
Cystic Fibrosis
Evaluation of a PNP care coordinator model for hospitalized children, adolescents, and young adults with cystic fibrosis.
Cysts
Toxoplasma gondii: localization of purine nucleoside phosphorylase activity in vitro and in vivo by electron microscopy.
Deficiency Diseases
Cockayne's syndrome fibroblasts are characterized by hypersensitivity to deoxyguanosine and abnormal DNA precursor pool metabolism in response to deoxyguanosine or ultraviolet light.
Deficiency Diseases
Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice.
Dehydration
Incorporating Born solvation energy into the three-dimensional Poisson-Nernst-Planck model to study ion selectivity in KcsA K^{+} channels.
Dementia
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
Demyelinating Diseases
Electrodiagnosis of polyneuropathy.
Demyelinating Diseases
Ultrasound differentiation of axonal and demyelinating neuropathies.
Demyelinating Diseases
[A case of Charcot-Marie-Tooth disease (CMT) type 1 complicated by diabetes mellitus (DM) showing bilateral phrenic nerve palsy]
Dendritic Cell Sarcoma, Follicular
Antibody titers to desmogleins 1 and 3 in a patient with paraneoplastic pemphigus associated with follicular dendritic cell sarcoma.
Dendritic Cell Sarcoma, Follicular
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus.
Dendritic Cell Sarcoma, Follicular
Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature.
Dendritic Cell Sarcoma, Follicular
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab.
Dendritic Cell Sarcoma, Follicular
Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma arising from Castleman's tumor.
Dendritic Cell Sarcoma, Follicular
Paraneoplastic pemphigus.
deoxyribonuclease ii deficiency
Lupus manifestations in children with primary immunodeficiency diseases: Comprehensive phenotypic and genetic features and outcome.
Dermatitis
Clinical phenotype and anti-desmoglein autoantibody profile in paraneoplastic pemphigus.
Dermatitis
Ectopic expression of epidermal antigens renders the lung a target organ in paraneoplastic pemphigus.
Dermatitis
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Dermatitis
Paraneoplastic pemphigus. A report of two cases associated with chronic B-cell lymphocytic leukaemia.
Dermatitis Herpetiformis
Bullous Diseases in Children: A Review of Clinical Features and Treatment Options.
Diabetes Mellitus
Classification of diabetic neuropathy from pathogenetic aspects.
Diabetes Mellitus
Clinical and nerve conduction studies in female patients with diabetic dermopathy.
Diabetes Mellitus
Clinical relevance of neurological evaluation in patients suffering urinary retention in the absence of subvesical obstruction.
Diabetes Mellitus
Deterioration of cardiac autonomic function over a period of one year in relation to cardiovascular and somatic neuropathy complications in type 2 diabetes mellitus.
Diabetes Mellitus
Exploring the mitochondrial microRNA import pathway through Polynucleotide Phosphorylase (PNPase).
Diabetes Mellitus
Peripheral neuropathy in patients with myotonic dystrophy type 1.
Diabetes Mellitus
Peripheral polyneuropathy after acute methanol poisoning: Six-year prospective cohort study.
Diabetes Mellitus
The effects of hyperventilation on axonal excitability parameters in patients with diabetes mellitus and polyneuropathy.
Diabetes Mellitus, Type 1
Diabetic polyneuropathy relates to bone metabolism and markers of bone turnover in elderly patients with type 2 diabetes: greater effects in male patients.
Diabetes Mellitus, Type 1
Retinal Microcirculation in Type 1 Diabetic Patients With and Without Peripheral Sensory Neuropathy.
Diabetes Mellitus, Type 2
Deterioration of cardiac autonomic function over a period of one year in relation to cardiovascular and somatic neuropathy complications in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Diabetic polyneuropathy relates to bone metabolism and markers of bone turnover in elderly patients with type 2 diabetes: greater effects in male patients.
Diabetes Mellitus, Type 2
Exploring the mitochondrial microRNA import pathway through Polynucleotide Phosphorylase (PNPase).
Diabetes Mellitus, Type 2
VEMP responses are not affected in non-insulin-dependent diabetes mellitus patients with or without polyneuropathy.
Diabetic Foot
Clinical and nerve conduction studies in female patients with diabetic dermopathy.
Diabetic Foot
Is diabetic dermopathy a sign for severe neuropathy in patients with diabetes mellitus? Nerve conduction studies and symptom analysis.
Diabetic Nephropathies
Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis.
Diabetic Neuropathies
Diabetic neuropathy examination: a hierarchical scoring system to diagnose distal polyneuropathy in diabetes.
Diabetic Neuropathies
Diabetic polyneuropathy relates to bone metabolism and markers of bone turnover in elderly patients with type 2 diabetes: greater effects in male patients.
Diabetic Neuropathies
[Autonomic symptoms in diabetic polyneuropathies]
Diabetic Retinopathy
The prognostic value of peripheral retinal nonperfusion in diabetic retinopathy using ultra-widefield fluorescein angiography.
dihydropyrimidinase deficiency
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
dihydropyrimidinase deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
Dihydropyrimidine Dehydrogenase Deficiency
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
Dihydropyrimidine Dehydrogenase Deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
Diphtheria
Clinical Trials and Treatment of ATL.
Diphtheria
Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells.
Diphtheria
[Adult T cell leukemia-lymphoma (ATL)].
Down Syndrome
Erythrocyte adenosine deaminase, purine nucleoside phosphorylase and phosphoribosyltransferase activity in patients with Down's syndrome.
Down Syndrome
Levels of some purine metabolizing enzymes in lymphocytes from patients with Down's syndrome.
Dry Eye Syndromes
Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report.
Dyspnea
Clinical Analysis of Unicentric Castleman's Disease with Paraneoplastic Pemphigus and Bronchiolitis Obliterans.
Dyspnea
[Phrenic nerve palsy after open heart surgery--problems in post-operative respiratory management]
Dystonia
Peripheral Neuropathic Pain and Pain Related to Complex Regional Pain Syndrome with and without Fixed Dystonia - Efficient Therapeutic Approach with Local Anesthetics.
Ectodermal Dysplasia
Inborn errors of immunity associated with characteristic phenotypes.
Endometrial Neoplasms
Atypical paraneoplastic pemphigus secondary to endometrial carcinoma with no mucosal involvement.
Endometriosis
Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility.
Endophthalmitis
Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report.
Epidermolysis Bullosa
Bullous Diseases in Children: A Review of Clinical Features and Treatment Options.
Epidermolysis Bullosa Acquisita
Bullous Diseases in Children: A Review of Clinical Features and Treatment Options.
Epistaxis
Nasal self-packing for epistaxis in Hereditary Hemorrhagic Telangiectasia increases quality of life.
Erectile Dysfunction
Polyneuropathy in impotence.
Erythema
Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus.
Erythema
Prognostic Factors of Paraneoplastic Pemphigus.
Exanthema
Predictors of Persistent Neuropathic Pain--A Systematic Review.
Fabry Disease
Bridging the Gap Between Vessels and Nerves in Fabry Disease.
Facial Paralysis
Severe ataxia with neuropathy in hereditary gelsolin amyloidosis.
Facial Paralysis
Severe ataxia with neuropathy in hereditary gelsolin amyloidosis: a case report.
Fatty Liver
Protective role of parnaparin in reducing systemic inflammation and atherosclerotic plaque formation in ApoE-/- mice.
Fibromyalgia
Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia.
Fibromyalgia
Mirogabalin: First Global Approval.
Foot Ulcer
Back to basics in diagnosing diabetic polyneuropathy with the tuning fork!
Foot Ulcer
Is diabetic dermopathy a sign for severe neuropathy in patients with diabetes mellitus? Nerve conduction studies and symptom analysis.
Foot Ulcer
Neuropathy patterns differ in patients with diabetic complications.
Gastroparesis
Collateral Nervous Damages After Cryoballoon Pulmonary Vein Isolation.
Gaucher Disease
Polyneuropathy in Gaucher disease type 1 and 3 - a descriptive case series.
Genetic Diseases, Inborn
Correcting human mitochondrial mutations with targeted RNA import.
Genetic Diseases, Inborn
Engineering Cell-Permeable Proteins through Insertion of Cell-Penetrating Motifs into Surface Loops.
Genetic Diseases, Inborn
Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency.
Genetic Diseases, Inborn
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.
Genetic Diseases, Inborn
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.
Glaucoma
Clinical role of gasless laparoscopic adrenalectomy.
Glioblastoma
Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide gene-transducing replication-competent foamy virus vectors.
Glioblastoma
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.
Glioma
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.
Glioma
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.
Glioma
Distribution of phosphoneuroprotein 14 (PNP 14) in vertebrates: its levels as determined by enzyme immunoassay.
Glioma
Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.
Glioma
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
Glioma
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase.
Glioma
LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma.
Glioma
PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.
Glioma
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X
Glioma
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Glioma
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.
Glucose Intolerance
Peripheral neuropathy in patients with myotonic dystrophy type 1.
Glucose Intolerance
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).
Glucose Metabolism Disorders
Antidiabetic effects of water-soluble Korean pine nut protein on type 2 diabetic mice.
Gout
Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography.
Gout
Determination of plasma purine nucleoside phosphorylase activity by high-performance liquid chromatography.
Gout
Erythrocyte adenosine deaminase and purine nucleoside phosphorylase activity in gout.
Gout
Four generations of transition-state analogues for human purine nucleoside phosphorylase.
Gout
[Metabolism of purine nucleotides and the production of uric acid]
Graft vs Host Disease
Fatal graft versus host disease after platelet transfusions in a child with purine nucleoside phosphorylase deficiency.
guanidinoacetate n-methyltransferase deficiency
Expanded newborn screening by mass spectrometry: New tests, future perspectives.
Guillain-Barre Syndrome
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies.
Hashimoto Disease
Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease.
Hearing Loss
A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss.
Hearing Loss
PNPase knockout results in mtDNA loss and an altered metabolic gene expression program.
Heart Defects, Congenital
Acute care pediatric nurse practitioner: a vital role in pediatric cardiothoracic surgery.
Heart Failure
[Using PNP value-guided therapy for treatment of heart failure is not better than using symptom-guided therapy].
Hemangioma
Promotion of Propranolol Delivery to Hemangiomas by Using Anti-VEGFR Antibody-Conjugated Poly(lactic-co-glycolic acid) Nanoparticles.
Hematologic Diseases
[Adenosine deaminase and purine nucleoside phosphorylase of thrombocytes in various hematologic diseases]
Hematologic Diseases
[Thrombocyte purine nucleoside phosphorylase in various blood diseases]
Hematologic Neoplasms
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
Hematologic Neoplasms
Forodesine: review of preclinical and clinical data.
Hematologic Neoplasms
Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes-A novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.
Hematologic Neoplasms
[Adenosine deaminase and purine nucleoside phosphorylase activities of various cultured cell lines derived from human hematologic malignancies]
Hepatitis
[Purine-nucleoside phosphorylase activity of the blood and hepatic and splenic tissue of mice during experimental hepatitis caused by MHV virus]
Hepatolenticular Degeneration
Expanded newborn screening by mass spectrometry: New tests, future perspectives.
Hereditary Sensory and Motor Neuropathy
Diagnostic accuracy of nerve ultrasound in hereditary and sporadic non-entrapment neuropathies.
Hereditary Sensory and Motor Neuropathy
Practically applicable nerve ultrasound models for the diagnosis of axonal and demyelinating hereditary motor and sensory neuropathies (HMSN).
Herpes Simplex
An enhancer in the first intron of the human purine nucleoside phosphorylase-encoding gene.
Herpes Simplex
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.
Herpes Simplex
Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir.
Herpes Simplex
Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene.
Herpes Simplex
Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro.
Herpes Simplex
Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
Hodgkin Disease
Blood lymphocytes in chronic lymphocytic leukaemia and Hodgkin's disease: Immunological features and enzymes of nucleoside metabolism.
Hodgkin Disease
Decreased adenosine deaminase (ADA) and 5'nucleotidase (5NT) activity in peripheral blood T cells in Hodgkin disease.
Hodgkin Disease
Multienzymatic analyses of human malignant lymphomas. Correlation of enzymatic data with pathologic and ultrastructural findings in Burkitt's and lymphoblastic lymphomas.
Hodgkin Disease
Neuropathy in lymphoma: a relationship between the pattern of neuropathy, type of lymphoma and prognosis?
Hyperalgesia
A multicentre, open-label, follow-on study to assess the long-term maintenance of effect, tolerance and safety of THC/CBD oromucosal spray in the management of neuropathic pain.
Hyperalgesia
Expert Opinion: Exploring the Effectiveness and Tolerability of Capsaicin 179 mg Cutaneous Patch and Pregabalin in the Treatment of Peripheral Neuropathic Pain.
Hyperalgesia
Is heat hypoalgesia a useful parameter in quantitative thermal testing of alcoholic polyneuropathy?
Hyperalgesia
Puerarin suppresses TRPV1, calcitonin gene-related peptide and substance P to prevent paclitaxel-induced peripheral neuropathic pain in rats.
Hyperglycemia
Prevalence and related risk-factors of peripheral neuropathy in children with insulin-dependent diabetes mellitus.
Hyperglycemia
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).
Hyperlipidemias
Chemical composition, antioxidant activities of polysaccharide from Pine needle (Pinus massoniana) and hypolipidemic effect in high-fat diet-induced mice.
Hyperlipidemias
[Multiple symmetrical lipomatosis with familial polineuropathy]
Hypersensitivity
Cinobufacini protects against paclitaxel-induced peripheral neuropathic pain and suppresses TRPV1 up-regulation and spinal astrocyte activation in rats.
Hypersensitivity
Inducible nitric oxide synthase inhibition by 1400W limits pain hypersensitivity in a neuropathic pain rat model.
Hypersensitivity
Involvement of pnp in survival to UV radiation in Escherichia coli K12.
Hypersensitivity
L5 spinal nerve axotomy induces sensitization of cutaneous L4 A?-nociceptive dorsal root ganglion neurons in the rat in vivo.
Hypersensitivity
PG110, A Humanized Anti-NGF Antibody, Reverses Established Pain Hypersensitivity in Persistent Inflammatory Pain, but not Peripheral Neuropathic Pain, Rat Models.
Hypersensitivity
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.
Hypersensitivity
Tn5 insertion in the polynucleotide phosphorylase (pnp) gene in Escherichia coli increases susceptibility to antibiotics.
Hypertension
Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
Hypertensive Retinopathy
Clinical role of gasless laparoscopic adrenalectomy.
Hyperthyroidism
Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats : Induction of phenol UDP-glucuronyltransferase by methimazole.
Hypoglycemia
The role of the pediatric nurse practitioner in a neonatal unit.
Hypoprothrombinemias
Diagnosis of lupus anticoagulant in the lupus anticoagulant-hypoprothrombinemia syndrome: report of two cases and review of the literature.
Hypothyroidism
Effects of thyroid status and thyrostatic drugs on hepatic glucuronidation of lodothyronines and other substrates in rats : Induction of phenol UDP-glucuronyltransferase by methimazole.
hypoxanthine phosphoribosyltransferase deficiency
Altered purine and pyrimidine metabolism in erythrocytes with purine nucleoside phosphorylase deficiency.
hypoxanthine phosphoribosyltransferase deficiency
Decreased S-adenosylhomocysteine hydrolase in inborn errors of purine metabolism.
hypoxanthine phosphoribosyltransferase deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
hypoxanthine phosphoribosyltransferase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
hypoxanthine phosphoribosyltransferase deficiency
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
IgA Deficiency
The First Purine Nucleoside Phosphorylase Deficiency Patient Resembling IgA Deficiency and a Review of the Literature.
Immune System Diseases
First trimester diagnosis of Lesch-Nyhan syndrome: applications to other disorders of purine metabolism.
Immunoglobulin Light-chain Amyloidosis
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Infections
A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma.
Infections
A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels.
Infections
A plant natriuretic peptide-like molecule of the pathogen Xanthomonas axonopodis pv. citri causes rapid changes in the proteome of its citrus host.
Infections
Albumin-Based LL37 Peptide Nanoparticles as a Sustained Release System against Pseudomonas aeruginosa Lung Infection.
Infections
An immunocompetent murine model for oncolysis with an armed and targeted measles virus.
Infections
An unconditioned bone marrow transplantation in a child with purine nucleoside phosphorylase deficiency and its unique complication.
Infections
Bacterial and plant natriuretic peptides improve plant defence responses against pathogens.
Infections
Calcitonin-specific transcription and splicing targets gene-directed enzyme prodrug therapy to medullary thyroid carcinoma cells.
Infections
Clinical Outcomes After Neurolysis for the Treatment of Peroneal Nerve Palsy: A Systematic Review and Meta-Analysis.
Infections
Cross correction following haemopoietic stem cell transplant for purine nucleoside phosphorylase deficiency: engrafted donor-derived white blood cells provide enzyme to residual enzyme-deficient recipient cells.
Infections
Detection rates of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, and swine influenza virus in porcine proliferative and necrotizing pneumonia.
Infections
Immunological Characteristics in Refractory Chronic Rhinosinusitis with Nasal Polyps Undergoing Revision Surgeries.
Infections
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
Infections
Novel mutations and hot-spots in patients with purine nucleoside phosphorylase deficiency.
Infections
Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity.
Infections
Paraneoplastic Pemphigus: Paraneoplastic Autoimmune Disease of the Skin and Mucosa.
Infections
Pneumococcal necrotizing pneumonia in Utah: does serotype matter?
Infections
Polynucleotide phosphorylase independently controls virulence factor expression levels and export in Yersinia spp.
Infections
Polynucleotide phosphorylase negatively controls spv virulence gene expression in Salmonella enterica.
Infections
Predictive variables for peripheral neuropathy in treated HIV type 1 infection revealed by machine learning.
Infections
Proliferative and necrotising pneumonia and severe vascular lesions in pigs naturally infected with porcine circovirus type 2.
Infections
Purine enzyme activities in recent onset rheumatoid arthritis: are there differences between patients and healthy controls?
Infections
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.
Infections
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.
Infections
Purine nucleoside phosphorylase deficiency with fatal course in two sisters.
Infections
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
Infections
Sexually Transmitted Infections and Children: What the PNP Should Know.
Infections
Targeted expression of E. coli purine nucleoside phosphorylase and Fludara for prostate cancer therapy.
Infections
The First Purine Nucleoside Phosphorylase Deficiency Patient Resembling IgA Deficiency and a Review of the Literature.
Infections
The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans.
Infections
[Purine nucleoside phosphorylase activity in serum, liver and spleen tissue during the course of experimental infection with MHV-3 virus]
Infectious Mononucleosis
Adenosine deaminase, purine nucleoside phosphorylase and 5'-nucleotidase activities in infectious mononucleosis.
Inflammatory Bowel Diseases
Studies on purine enzymes in experimental colitis.
Influenza, Human
Design of N-acetyl-6-sulfo-beta-d-glucosaminide-based inhibitors of influenza virus sialidase.
Influenza, Human
Prolonged Codelivery of Hemagglutinin and a TLR7/8 Agonist in a Supramolecular Polymer-Nanoparticle Hydrogel Enhances Potency and Breadth of Influenza Vaccination.
Insulin Resistance
Antidiabetic effects of water-soluble Korean pine nut protein on type 2 diabetic mice.
Intellectual Disability
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Intervertebral Disc Degeneration
The impact of generalized joint laxity (GJL) on the posterior neck pain, cervical disc herniation, and cervical disc degeneration in the cervical spine.
Intervertebral Disc Displacement
[Clinical significance on protruded nucleus pulposus: a comparative study of 44 patients with lumbar intervertebral disc protrusion and 73 asymptomatic control in tridimentional computed tomography]
Job Syndrome
Inborn errors of immunity associated with characteristic phenotypes.
Job Syndrome
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies.
Kidney Failure, Chronic
[Effects of kidney and pancreas transplantation on neurophysiological rates of polyneuropathy and autonomous cardiac function in diabetic patients with end-stage renal disease]
Kyphosis
Predictive factors associated with neck pain in patients with cervical disc degeneration: A cross-sectional study focusing on Modic changes.
Laryngeal Neoplasms
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Leishmaniasis, Cutaneous
In Vitro Immunomodulatory Activity of a Transition-State Analog Inhibitor of Human Purine Nucleoside Phosphorylase in Cutaneous Leishmaniasis.
Lesch-Nyhan Syndrome
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: preliminary in vitro studies with analogues of immucillin-G.
Lesch-Nyhan Syndrome
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
Lesch-Nyhan Syndrome
Use of intact erythrocytes in the diagnosis of inherited purine and pyrimidine disorders.
Leukemia
A comparison of some leucocyte differentiation markers and the adenosine deaminase and purine nucleoside phosphorylase values in B and T cell leukemias and lymphomas.
Leukemia
A nelarabine-resistant T-lymphoblastic leukemia CCRF-CEM variant cell line is cross-resistant to the purine nucleoside phosphorylase inhibitor forodesine.
Leukemia
A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).
Leukemia
A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells.
Leukemia
Adenosine deaminase and purine nucleoside phosphorylase in acute and chronic lymphatic leukemia.
Leukemia
Adenosine deaminase and purine nucleoside phosphorylase levels in acute myeloblastic leukemia cells. Relationship to diagnosis and clinical course.
Leukemia
Catalytic Site Conformations in Human PNP by (19)F-NMR and Crystallography.
Leukemia
Changes in the activities of cytidine deaminase during differentiation of HL60 cells induced by 1,25 dihydroxy D3.
Leukemia
Characterization of purine nucleoside phosphorylase in leukemia.
Leukemia
Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.
Leukemia
Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.
Leukemia
Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency.
Leukemia
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Leukemia
Differential expression of adenosine deaminase isozymes in acute leukemia.
Leukemia
Differential expression pattern of protein markers for predicting chemosensitivity of dexamethasone-based chemotherapy of B cell acute lymphoblastic leukemia.
Leukemia
Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor.
Leukemia
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Leukemia
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia
Enzymes of the purine interconversion system in chronic lymphatic leukemia: decreased purine nucleoside phosphorylase and adenosine deaminase activity.
Leukemia
Four generations of transition-state analogues for human purine nucleoside phosphorylase.
Leukemia
Genetic deficiencies of adenosine deaminase and purine nucleoside phosphorylase and their implications for therapy of leukemias.
Leukemia
Isolation and expression of a murine purine nucleoside phosphorylase-encoding cDNA and sequence similarity with the human message.
Leukemia
Lymphoblast purine pathway enzymes in B-cell acute lymphoblastic leukemia.
Leukemia
Novel purine nucleoside analogues for hematological malignancies.
Leukemia
Purine metabolism in childhood acute lymphoblastic leukemia: biochemical markers for diagnosis and chemotherapy.
Leukemia
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.
Leukemia
Relation of some cytochemical activities to the expression of CD34 marker in acute leukemia.
Leukemia
Significance of enzyme markers as a part of multiple marker analysis in leukemia research.
Leukemia
Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040.
Leukemia
[Adenosine deaminase, purine nucleoside phosphorylase and ecto-5'-nucleotidase--markers of acute leukemia variants]
Leukemia
[Purine nucleoside phosphorylase activity in childhood acute leukemia]
Leukemia, Lymphocytic, Chronic, B-Cell
Adenosine deaminase and purine nucleoside phosphorylase in acute and chronic lymphatic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Characterization of purine nucleoside phosphorylase in leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia, Lymphocytic, Chronic, B-Cell
Enzymes of the purine interconversion system in chronic lymphatic leukemia: decreased purine nucleoside phosphorylase and adenosine deaminase activity.
Leukemia, Lymphocytic, Chronic, B-Cell
Enzymological studies in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells.
Leukemia, Lymphocytic, Chronic, B-Cell
Intralymphocytic adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNPase) activity in chronic lymphocytic leukemia (CLL): effect of thymostimulin.
Leukemia, Lymphocytic, Chronic, B-Cell
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Leukemia, Lymphocytic, Chronic, B-Cell
Paraneoplastic Pemphigus Associated with B-cell Chronic Lymphocytic Leukemia Treated with Ibrutinib and Rituximab.
Leukemia, Lymphocytic, Chronic, B-Cell
Paraneoplastic pemphigus with a pemphigus vegetans-like plaque as the only cutaneous manifestation.
Leukemia, Lymphocytic, Chronic, B-Cell
Paraneoplastic pemphigus.
Leukemia, Lymphocytic, Chronic, B-Cell
Purine nucleoside phosphorylase in chronic lymphocytic leukemia (CLL).
Leukemia, Lymphocytic, Chronic, B-Cell
The effects of forodesine in murine and human multiple myeloma cells.
Leukemia, Lymphocytic, Chronic, B-Cell
[Enzymes of purine nucleotide catabolism in lymphocytes in normal states and in chronic lymphoid leukemia]
Leukemia, Lymphoid
Combined assay of adenosine deaminase, purine nucleoside phosphorylase, and lactate dehydrogenase in the early clinical evaluation of B-chronic lymphocytic leukemia.
Leukemia, Lymphoid
Enzymes of purine metabolism in B-chronic lymphocytic leukemia.
Leukemia, Lymphoid
Methylthioadenosine phosphorylase and purine nucleoside phosphorylase in B-chronic lymphocytic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Differential expression of adenosine deaminase isozymes in acute leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[Certain biochemical features of leukocytes in blast crisis of chronic myelogenous leukemia]
Leukemia, Myeloid, Acute
Adenosine deaminase and purine nucleoside phosphorylase levels in acute myeloblastic leukemia cells. Relationship to diagnosis and clinical course.
Leukemia, Myeloid, Acute
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Leukemia, Myeloid, Acute
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Leukemia, Myeloid, Acute
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Leukemia, Myeloid, Acute
Purine degradative enzymes and terminal transferase in acute myelogenous leukemia: clinical relevance.
Leukemia, Prolymphocytic
Enzymatic differences between chronic lymphocytic leukemia and prolymphocytic leukemia.
Leukemia, T-Cell
A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells.
Leukemia, T-Cell
Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.
Leukemia, T-Cell
Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.
Leukemia, T-Cell
Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.
Leukemia, T-Cell
Discovery of a Novel Inhibitor of Human Purine Nucleoside Phosphorylase by a Simple Hydrophilic Interaction Liquid Chromatography Enzymatic Assay.
Leukemia, T-Cell
Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange.
Leukemia, T-Cell
Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues.
Leukemia, T-Cell
Preclinical and clinical evaluation of forodesine in pediatric and adult B-cell acute lymphoblastic leukemia.
Leukemia, T-Cell
Structure-based design of inhibitors of purine nucleoside phosphorylase.
Leukoencephalopathies
Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.
Leukoencephalopathy, Progressive Multifocal
Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.
Lichen Planus
Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus.
Lichen Planus
Paraneoplastic pemphigus in association with a retroperitoneal Castleman's disease presenting with a lichen planus pemphigoides-like eruption. A case report and review of literature.
Linear IgA Bullous Dermatosis
Serum plakophilin-3 autoreactivity in paraneoplastic pemphigus.
Liver Failure, Acute
Network pharmacology based investigation into the bioactive compounds and molecular mechanisms of Schisandrae Chinensis Fructus against drug-induced liver injury.
Liver Neoplasms, Experimental
Evidence for role of purine nucleoside phosphorylase in sensitivity of Novikoff hepatoma cells to 5-fluorouracil.
Lung Abscess
[Localized Castleman disease with paraneoplastic pemphigus and pulmonary involvement: clinical features and histopathology]
Lung Diseases
Late diagnosis and correction of purine nucleoside phosphorylase deficiency with allogeneic bone marrow transplantation.
Lung Neoplasms
Adenosine deaminase and purine nucleoside phosphorylase activities in lymphocytes from patients with lung cancer.
Lung Neoplasms
Changes in lymphocyte adenosine deaminase and purine nucleoside phosphorylase levels in lung cancer after radical surgery.
Lung Neoplasms
Effect of TEI-6720, a xanthine oxidase inhibitor, on the nucleoside transport in the lung cancer cell line A549.
Lung Neoplasms
[Diagnosis and treatment of lung cancer in polyneoplasia]
Lupus Erythematosus, Systemic
A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma.
Lupus Erythematosus, Systemic
Reduced purine nucleoside phosphorylase activity in preparations of enriched T-lymphocytes from patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Sniff esophageal and nasopharyngeal pressures and maximal relaxation rates in patients with respiratory dysfunction.
Lymphatic Metastasis
Analysis of tumor-induced lymphangiogenesis and lymphatic vessel invasion of pancreatic carcinoma in the peripheral nerve plexus.
Lymphocytosis
Enzymes of purine metabolism in B-chronic lymphocytic leukemia.
Lymphoma
9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.
Lymphoma
A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma.
Lymphoma
A comparison of some leucocyte differentiation markers and the adenosine deaminase and purine nucleoside phosphorylase values in B and T cell leukemias and lymphomas.
Lymphoma
A nonfatal case and 2 fatal cases of paraneoplastic pemphigus: can a complement indirect immunofluorescent test help to identify fatal "group A" paraneoplastic pemphigus cases?
Lymphoma
Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.
Lymphoma
Clinical features distinguishing lymphoma development in primary Sjögren's syndrome-A retrospective cohort study.
Lymphoma
Clinical management of T-cell malignancies: current perspectives, key issues, and emerging therapies.
Lymphoma
Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency.
Lymphoma
Cutaneous paraneoplastic pemphigus syndrome associated with undifferentiated uterine sarcoma.
Lymphoma
Demonstration of induction of erythrocyte inosine monophosphate dehydrogenase activity in Ribavirin-treated patients using a high performance liquid chromatography linked method.
Lymphoma
Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor.
Lymphoma
Multicenter phase 1/2 study of forodesine in patients with relapsed peripheral T cell lymphoma.
Lymphoma
Multienzymatic analyses of human malignant lymphomas. Correlation of enzymatic data with pathologic and ultrastructural findings in Burkitt's and lymphoblastic lymphomas.
Lymphoma
Simultaneous assay of adenosine deaminase and purine nucleoside phosphorylase activity as possible biochemical means to detect non-Hodgkin lymphomas of the oral cavity.
Lymphoma
Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040.
Lymphoma, B-Cell
General anesthetic management for diagnostic splenectomy in a patient with paraneoplastic pemphigus.
Lymphoma, B-Cell
Paraneoplastic Pemphigus and Bronchiolitis Obliterans in a Patient with Splenic B-cell Lymphoma.
Lymphoma, B-Cell
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and intractable mucosal erosions: Treatment with cyclosporin in addition to steroid, rituximab and intravenous immunoglobulin.
Lymphoma, B-Cell
Using rituximab (anti-CD20 antibody) in a patient with paraneoplastic pemphigus.
Lymphoma, Follicular
Mucocutaneous paraneoplastic syndromes associated with hematologic malignancies.
Lymphoma, Follicular
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Lymphoma, Follicular
Rationale and efficacy for the use of rituximab in paraneoplastic pemphigus.
Lymphoma, Follicular
Therapy of paraneoplastic pemphigus with Rituximab: a case report and review of literature.
Lymphoma, Non-Hodgkin
Activity of adenosine deaminase and of purine nucleoside phosphorylase in peripheral lymphocytes from patients with acquired immunological disorders.
Lymphoma, Non-Hodgkin
Excessive chemotherapy-related granulocytopenia in a child with non-Hodgkin's lymphoma and a congenital abnormality of purine salvage.
Lymphoma, Non-Hodgkin
Multienzymatic analyses of human malignant lymphomas. Correlation of enzymatic data with pathologic and ultrastructural findings in Burkitt's and lymphoblastic lymphomas.
Lymphoma, Non-Hodgkin
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Lymphoma, Non-Hodgkin
Paraneoplastic pemphigus associated with bronchiolitis obliterans.
Lymphoma, Non-Hodgkin
Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report.
Lymphoma, Non-Hodgkin
Paraneoplastic pemphigus.
Lymphoma, Non-Hodgkin
Paraneoplastic pemphigus: a case report and review of literature.
Lymphoma, Non-Hodgkin
Pyrimidine and purine activities in non-Hodgkin's lymphoma. Correlation with histological status and survival.
Lymphoma, T-Cell
Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency.
Lymphoma, T-Cell, Cutaneous
Evidence for a pathway independent from 2'-deoxyguanosine and reversible by IL-2 by which purine nucleoside phosphorylase inhibitors block T-cell proliferation.
Lymphoma, T-Cell, Cutaneous
Final results of a multicenter phase II study of the purine nucleoside phosphorylase (PNP) inhibitor forodesine in patients with advanced cutaneous T-cell lymphomas (CTCL) (Mycosis fungoides and Sézary syndrome).
Lymphoma, T-Cell, Cutaneous
Novel purine nucleoside analogues for hematological malignancies.
Lymphoma, T-Cell, Cutaneous
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.
Lymphoma, T-Cell, Cutaneous
Purine pathway enzymes in the circulating malignant cells of patients with cutaneous T-cell lymphoma.
Lymphopenia
A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).
Lymphopenia
Cross correction following haemopoietic stem cell transplant for purine nucleoside phosphorylase deficiency: engrafted donor-derived white blood cells provide enzyme to residual enzyme-deficient recipient cells.
Lymphopenia
Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells.
Lymphopenia
Forodesine: review of preclinical and clinical data.
Lymphopenia
Novel mutations and hot-spots in patients with purine nucleoside phosphorylase deficiency.
Lymphopenia
Pharmacology and mechanism of action of forodesine, a T-cell targeted agent.
Lymphopenia
Preclinical and clinical evaluation of forodesine in pediatric and adult B-cell acute lymphoblastic leukemia.
Lymphopenia
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.
Lymphopenia
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.
Lymphopenia
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
Lymphoproliferative Disorders
Achievement of the longest survival of paraneoplastic pemphigus with bronchiolitis obliterans associated with follicular lymphoma using R-CHOP chemotherapy.
Lymphoproliferative Disorders
Castleman disease and paraneoplastic pemphigus in a pregnant woman: A case report.
Lymphoproliferative Disorders
Effects of 8-aminoguanosine on the toxicity of guanosine and deoxyguanosine for malignant and normal lymphoid cells.
Lymphoproliferative Disorders
Purine nucleoside phosphorylase (PNP) and adenosine deaminase (ADA) activities examined cytochemically in unfixed lymphocytes of patients with lymphoproliferative disorders.
Lymphoproliferative Disorders
Purine nucleoside phosphorylase deficiency associated with a fatal lymphoproliferative disorder.
Lymphoproliferative Disorders
Purine nucleoside phosphorylase in chronic lymphocytic leukemia (CLL).
Lymphoproliferative Disorders
Sensitivity and specificity of clinical, histologic, and immunologic features in the diagnosis of paraneoplastic pemphigus.
Macrophage Activation Syndrome
An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome.
Malaria
Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity.
Malaria
Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.
Malaria
Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors.
Malaria
Identification of a novel putative inhibitor of the Plasmodium falciparum purine nucleoside phosphorylase: exploring the purine salvage pathway to design new antimalarial drugs.
Malaria
Immucillins in Infectious Diseases.
Malaria
Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites.
Malaria
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases.
Malaria
Targeting Plasmodium Falciparum Purine Salvage Enzymes: A Look At Structure-Based Drug Development.
Malaria
Targeting Plasmodium falciparum purine salvage enzymes: a look at structure-based drug development.
Malaria
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog.
Malaria, Cerebral
Experimental cerebral malaria is suppressed by disruption of nucleoside transporter 1 but not purine nucleoside phosphorylase.
Malnutrition
Effect of undernutrition on some enzymes of purine metabolism in different regions of developing rat brain.
Malnutrition
Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
Melanoma
Augmentation of melanoma-specific gene expression using a tandem melanocyte-specific enhancer results in increased cytotoxicity of the purine nucleoside phosphorylase gene in melanoma.
Melanoma
Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene.
Melanoma
Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence.
Melanoma
High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode.
Melanoma
Tumor-targeting Salmonella typhimurium, a natural tool for activation of prodrug 6MePdR and their combination therapy in murine melanoma model.
Melanoma
Up-regulation of human PNPase mRNA by beta-interferon has no effect on protein level in melanoma cell lines.
Metabolic Diseases
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
Metabolic Diseases
[Purine nucleoside phosphorylase (PNP) deficiency]
Metabolism, Inborn Errors
Cross correction following haemopoietic stem cell transplant for purine nucleoside phosphorylase deficiency: engrafted donor-derived white blood cells provide enzyme to residual enzyme-deficient recipient cells.
Miller Fisher Syndrome
A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies.
Mononeuropathies
Electromyography in Pediatric Population.
Mononeuropathies
Predictive variables for peripheral neuropathy in treated HIV type 1 infection revealed by machine learning.
Motor Neuron Disease
Vitamin D deficiency in patients with primary immune-mediated peripheral neuropathies.
Multiple Myeloma
Bortezomib-induced peripheral neuropathy: A genome-wide association study on multiple myeloma patients.
Multiple Sclerosis
Prevalence of anti-SOX1 reactivity in various neurological disorders.
Multiple System Atrophy
Prevalence and Characteristics of Polyneuropathy in Atypical Parkinsonian Syndromes: An Explorative Study.
Muscle Hypotonia
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
Muscle Weakness
The measurement of inspiratory muscle strength by sniff esophageal, nasopharyngeal, and mouth pressures.
Muscular Diseases
Electromyography in Pediatric Population.
Muscular Dystrophy, Duchenne
Expanded newborn screening by mass spectrometry: New tests, future perspectives.
Myasthenia Gravis
Activities of purine nucleotide metabolizing enzymes in human thymocytes and peripheral blood T lymphocytes: in vitro effect of thymic hormones.
Myasthenia Gravis
Castleman's Disease with Paraneoplastic Pemphigus.
Myasthenia Gravis
Paraneoplastic pemphigus and myasthenia gravis as the first manifestations of a rare case of pancreatic follicular dendritic cell sarcoma: CT findings and review of literature.
Myasthenia Gravis
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab.
Mycosis Fungoides
Evidence for a pathway independent from 2'-deoxyguanosine and reversible by IL-2 by which purine nucleoside phosphorylase inhibitors block T-cell proliferation.
Myeloproliferative Disorders
[Adenosine deaminase (ADA), 5'-nucleotidase (5'N) and purine nucleoside phosphorylase (PNP) in lympho- and myeloproliferative disorders]
Neoplasm Metastasis
Analysis of tumor-induced lymphangiogenesis and lymphatic vessel invasion of pancreatic carcinoma in the peripheral nerve plexus.
Neoplasm Metastasis
Impact of pneumoperitoneum on visceral metastasis rate and survival. Results in two ovarian cancer models in rats.
Neoplasms
2-Chloro-2'-deoxyadenosine (cladribine) and its analogues are good substrates and potent selective inhibitors of Escherichia coli purine-nucleoside phosphorylase.
Neoplasms
4-nitrophenol exposure in T24 human bladder cancer cells promotes proliferation, motilities, and epithelial-to-mesenchymal transition.
Neoplasms
5-Iodoribose 1-phosphate, an analog of ribose 1-phosphate. Enzymatic synthesis and kinetic studies with enzymes of purine, pyrimidine, and sugar phosphate metabolism.
Neoplasms
6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases.
Neoplasms
6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase.
Neoplasms
9-Deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid are slow-binding picomolar inhibitors of trimeric purine nucleoside phosphorylase.
Neoplasms
A Case of Severe Refractory Pemphigus Vulgaris in a Patient With Stable Esophageal Malignancy.
Neoplasms
A critical role of surgery in the treatment for paraneoplastic pemphigus caused by localized Castleman's disease.
Neoplasms
A human biotin acceptor domain allows site-specific conjugation of an enzyme to an antibody-avidin fusion protein for targeted drug delivery.
Neoplasms
A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration.
Neoplasms
A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels.
Neoplasms
A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine).
Neoplasms
Absent well-characterized onconeural antibodies in 283 patients with various polyneuropathies: A retrospective monocenter study.
Neoplasms
Adenosine deaminase and purine nucleoside phosphorylase activities in peripheral lymphocytes from patients with solid tumours.
Neoplasms
Adenosine deaminase and purine phosphorylase activities in lymphocytes and red blood cells of patients with carcinoma of the larynx.
Neoplasms
Altered Enthalpy-Entropy Compensation in Picomolar Transition State Analogues of Human Purine Nucleoside Phosphorylase.
Neoplasms
Analysis of tumor-induced lymphangiogenesis and lymphatic vessel invasion of pancreatic carcinoma in the peripheral nerve plexus.
Neoplasms
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.
Neoplasms
Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.
Neoplasms
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.
Neoplasms
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus.
Neoplasms
Bioconjugated Fluorescent Polymeric Nanoparticles for Imaging and Targeted Therapy of HER2-Overexpressing Cancer Cells.
Neoplasms
Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene.
Neoplasms
Clinical Analysis of Unicentric Castleman's Disease with Paraneoplastic Pemphigus and Bronchiolitis Obliterans.
Neoplasms
Clinical and immunopathological spectrum of paraneoplastic pemphigus.
Neoplasms
Contributions of protein structure-based drug design to cancer chemotherapy.
Neoplasms
Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Neoplasms
Differential expression pattern of protein markers for predicting chemosensitivity of dexamethasone-based chemotherapy of B cell acute lymphoblastic leukemia.
Neoplasms
Direct detection of cancer biomarkers in blood using a "place n play" modular polydimethylsiloxane pump.
Neoplasms
Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor.
Neoplasms
Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.
Neoplasms
Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine.
Neoplasms
Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.
Neoplasms
Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene.
Neoplasms
Enzyme activities controlling adenosine levels in normal and neoplastic tissues.
Neoplasms
Enzymes of purine metabolism in hairy cell leukemia.
Neoplasms
Epitopes in the linker subdomain region of envoplakin recognized by autoantibodies in paraneoplastic pemphigus patients.
Neoplasms
Excellent in vivo bystander activity of fludarabine phosphate against human glioma xenografts that express the escherichia coli purine nucleoside phosphorylase gene.
Neoplasms
Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide gene-transducing replication-competent foamy virus vectors.
Neoplasms
Extremities of the N-terminus of envoplakin and C-terminus of its linker subdomain are major epitopes of paraneoplastic pemphigus.
Neoplasms
Fatal paraneoplastic pemphigus associated with a mediastinal tumor.
Neoplasms
Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature.
Neoplasms
Follicular non-Hodgkin's lymphoma with refractory paraneoplastic pemphigus: case report with review of novel treatment modalities.
Neoplasms
Forodesine in the treatment of relapsed/refractory peripheral T-cell lymphoma: an evidence-based review.
Neoplasms
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.
Neoplasms
Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase.
Neoplasms
Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene.
Neoplasms
Gene-directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease.
Neoplasms
Host-mediated inhibition of rat bladder cancer growth by cyclophosphamide and purine salvage pathway-related enzyme activity of lymphocytes.
Neoplasms
Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancer.
Neoplasms
Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma.
Neoplasms
Imaging characteristics of abdominal tumor in association with paraneoplastic pemphigus.
Neoplasms
Immunoglobulin variable region gene analysis to the autoantibody-secreting B cells from tumors in association with paraneoplastic autoimmune multiorgan syndrome.
Neoplasms
Improved outcomes after complete resection of underlying tumors for patients with paraneoplastic pemphigus: a single-center experience of 22 cases.
Neoplasms
In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase.
Neoplasms
In vivo gene therapy for prostate cancer: preclinical evaluation of two different enzyme-directed prodrug therapy systems delivered by identical adenovirus vectors.
Neoplasms
In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase.
Neoplasms
In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells.
Neoplasms
Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotides.
Neoplasms
Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
Neoplasms
Interferon alpha and 5'-deoxy-5-fluorouridine in colon cancer: effects as single agents and in combination on growth of xenograft tumours.
Neoplasms
Intra-abdominal inflammatory pseudotumor-like follicular dendritic cell sarcoma associated with paraneoplastic pemphigus: A case report and review of the literature.
Neoplasms
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Neoplasms
Large Stokes-shifted NIR-emission from nanospace-induced aggregation of perylenemonoimide-doped polymer nanoparticles: imaging of folate receptor expression.
Neoplasms
Masked pemphigus among pediatric patients with Castleman's disease.
Neoplasms
Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.
Neoplasms
Metabolites of Purine Nucleoside Phosphorylase (NP) in Serum Have the Potential to Delineate Pancreatic Adenocarcinoma.
Neoplasms
Mucocutaneous paraneoplastic syndromes associated with hematologic malignancies.
Neoplasms
Multienzymatic analyses of human malignant lymphomas. Correlation of enzymatic data with pathologic and ultrastructural findings in Burkitt's and lymphoblastic lymphomas.
Neoplasms
Mycoplasma hyorhinis-encoded purine nucleoside phosphorylase: kinetic properties and its effect on the cytostatic potential of purine-based anticancer drugs.
Neoplasms
Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer.
Neoplasms
Neoplasms associated with paraneoplastic pemphigus: a review with emphasis on non-hematologic malignancy and oral mucosal manifestations.
Neoplasms
Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer.
Neoplasms
Nuclear EGFR Suppresses Ribonuclease Activity of Polynucleotide Phosphorylase through DNAPK-mediated Phosphorylation at Serine 776.
Neoplasms
Oral presentation of paraneoplastic pemphigus as the first sign of tonsillar HPV associated squamous cell carcinoma. A case report.
Neoplasms
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Neoplasms
Paraneoplastic pemphigus associated with a pericardial ectopic thymoma.
Neoplasms
Paraneoplastic Pemphigus Associated with Follicular Dendritic Cell Tumor in the Mediastinum.
Neoplasms
Paraneoplastic pemphigus associated with uterine carcinoma.
Neoplasms
Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure.
Neoplasms
Paraneoplastic pemphigus in a dog with splenic sarcoma.
Neoplasms
Paraneoplastic pemphigus in association with hepatocellular carcinoma.
Neoplasms
Paraneoplastic pemphigus mimicking erosive mucosal lichen planus associated with primary hepatocellular carcinoma.
Neoplasms
Paraneoplastic pemphigus presenting with a single oral lesion.
Neoplasms
Paraneoplastic Pemphigus with Underlying Castleman's Disorder: A Rare Report with Literature Review.
Neoplasms
Paraneoplastic pemphigus.
Neoplasms
Paraneoplastic pemphigus: a case of long-term survival associated with systemic lupus erythematosus and polymyositis.
Neoplasms
Paraneoplastic pemphigus: a case report and review of literature.
Neoplasms
Paraneoplastic pemphigus: a report of two cases.
Neoplasms
Paraneoplastic pemphigus: a short review.
Neoplasms
Paraneoplastic Pemphigus: Paraneoplastic Autoimmune Disease of the Skin and Mucosa.
Neoplasms
Pharmacology and mechanism of action of forodesine, a T-cell targeted agent.
Neoplasms
Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors.
Neoplasms
Plasma purine nucleoside phosphorylase in cancer patients.
Neoplasms
PNP anticancer gene therapy.
Neoplasms
PNP inhibitors selectively kill cancer cells lacking SAMHD1.
Neoplasms
PNP with Waldenström's macroglobulinaemia.
Neoplasms
PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS.
Neoplasms
Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus.
Neoplasms
Preparation and evaluation of 99mTc-labeled porphyrin complexes prepared using PNP and HYNIC cores: studying the effects of core selection on pharmacokinetics and tumor uptake in a mouse model.
Neoplasms
Purine degradative enzymes and immunological phenotypes in chronic B-lymphocytic leukaemia: indications that leukaemic immunocytoma is a separate entity.
Neoplasms
Purine degradative enzymes in circulating malignant cells of patients with chronic B cell neoplasia.
Neoplasms
Purine metabolizing enzymes in lymphocytes from patients with solid tumors.
Neoplasms
Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer.
Neoplasms
Purine nucleoside phosphorylase deficiency with fatal course in two sisters.
Neoplasms
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.
Neoplasms
Purine nucleoside phosphorylase inhibitors in T-cell malignancies.
Neoplasms
Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer.
Neoplasms
Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy.
Neoplasms
Purine-Metabolising Enzymes and Apoptosis in Cancer.
Neoplasms
Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.
Neoplasms
Relationship between the levels of purine salvage pathway enzymes and clinical/biological aggressiveness of human colon carcinoma.
Neoplasms
Relative efficiency of tumor cell killing in vitro by two enzyme-prodrug systems delivered by identical adenovirus vectors.
Neoplasms
Role of autoantibodies against the linker subdomains of envoplakin and periplakin in the pathogenesis of paraneoplastic pemphigus.
Neoplasms
Sensitivity and specificity of clinical, histologic, and immunologic features in the diagnosis of paraneoplastic pemphigus.
Neoplasms
Separation and modification of the phosphorolytic and ribosyl transfer activities of the purine nucleoside phosphorylase of Ehrlich ascites tumor cells.
Neoplasms
Sinusoidal endothelial cell damage by activated macrophages in rat liver necrosis.
Neoplasms
Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes-pretreated and lipopolysaccharide-stimulated rat liver.
Neoplasms
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase.
Neoplasms
SPION and doxorubicin-loaded polymeric nanocarriers for glioblastoma theranostics.
Neoplasms
Synthesis of 9-(6-Deoxy-?-L-Talofuranosyl)-6-Methylpurine and 9-(6-Deoxy-?-D-Allofuranosyl)-6-Methylpurine Nucleosides.
Neoplasms
Targeted enzyme prodrug therapy for metastatic prostate cancer - a comparative study of L-methioninase, purine nucleoside phosphorylase, and cytosine deaminase.
Neoplasms
Targeted expression of E. coli purine nucleoside phosphorylase and Fludara for prostate cancer therapy.
Neoplasms
The correlation of adenosine deaminase and purine nucleoside phosphorylase activities in human lymphocytes subpopulations and in various lymphoid malignancies.
Neoplasms
The Proteomic Effects of Pulsed Focused Ultrasound on Tumor Microenvironments of Murine Melanoma and Breast Cancer Models.
Neoplasms
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Neoplasms
Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications.
Neoplasms
Tumor sensitization to purine analogs by E. coli PNP.
Neoplasms
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.
Neoplasms
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.
Neoplasms
Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors.
Neoplasms
[Basic and clinical research on paraneoplastic pemphigus]
Neoplasms
[Complications of percutaneous nephropyelostomy with special reference to the sonographic real-time puncture technic]
Neoplasms
[Diagnosis and treatment of lung cancer in polyneoplasia]
Neoplasms
[Localized Castleman disease with paraneoplastic pemphigus and pulmonary involvement: clinical features and histopathology]
Neoplasms
[Some inhibitors of purine nucleoside phosphorylase].
Neoplasms
[Surgical treatment and prognosis analysis of localized retroperitoneal Castleman disease: a study of 20 cases.]
Neoplasms
[The new development on pathogenesis of autoimmune paraneoplastic pemphigus.]
Neoplasms
[Treatment of paraneoplastic pemphigus with Castleman's disease]
Nervous System Diseases
Purine nucleoside phosphorylase deficiency with fatal course in two sisters.
Neural Tube Defects
Neural tube development in mutant (curly tail) and normal mouse embryos: the timing of posterior neuropore closure in vivo and in vitro.
Neuralgia
A comparison of the SF-36 and Nottingham Health Profile in patients with chronic neuropathic pain.
Neuralgia
A prospective, open-label, multicentre study of pregabalin in the treatment of neuropathic pain in Latin America.
Neuralgia
Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice.
Neuralgia
Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study.
Neuralgia
Efficacy and Safety of 0.625% and 1.25% Capsaicin Patch in Peripheral Neuropathic Pain: Multi-Center, Randomized, and Semi-Double Blind Controlled Study.
Neuralgia
Mirogabalin: First Global Approval.
Neuralgia
Patient-Tailored Combinations of Systemic and Topical Preparations for Localized Peripheral Neuropathic Pain: A Two-Case Report.
Neuralgia
Peripheral neuropathic pain in idiopathic Parkinson's disease: Prevalence and impact on quality of life; a case controlled study.
Neuralgia
Predictive variables for peripheral neuropathy in treated HIV type 1 infection revealed by machine learning.
Neuralgia
Predictors of Persistent Neuropathic Pain--A Systematic Review.
Neuralgia
Prevalence of central and peripheral neuropathic pain in patients attending pain clinics in Spain: factors related to intensity of pain and quality of life.
Neuralgia
Systematic review and network meta-analysis of the efficacy and safety of lidocaine 700?mg medicated plaster vs. pregabalin.
Neuralgia
[First results of clinical diagnostic analysis of post-COVID peripheral neuropathy].
Neuralgia, Postherpetic
A prospective, open-label, multicentre study of pregabalin in the treatment of neuropathic pain in Latin America.
Neuralgia, Postherpetic
The MOBILE Study-A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with Peripheral Neuropathic Pain.
Neuroblastoma
Distribution of phosphoneuroprotein 14 (PNP 14) in vertebrates: its levels as determined by enzyme immunoassay.
Neuroblastoma
Neuroblastoma-specific cytotoxicity mediated by the Mash1-promoter and E. coli purine nucleoside phosphorylase.
Neurodegenerative Diseases
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
Neurodegenerative Diseases
The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients.
Neurologic Manifestations
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.
Neurologic Manifestations
Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.
Neurologic Manifestations
Purine nucleoside phosphorylase deficiency: a new case report and identification of two novel mutations (Gly156A1a and Val217Ile), only one of which (Gly156A1a) is deleterious.
Neurologic Manifestations
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
Neurologic Manifestations
Stroke in purine nucleoside phosphorylase deficiency.
Neurologic Manifestations
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.
Neurologic Manifestations
The Broad Clinical Spectrum and Transplant Results of PNP Deficiency.
Neuroma
Non-invasive detection of corneal sub-basal nerve plexus changes in multiple myeloma patients by confocal laser scanning microscopy.
Neutropenia
Excessive chemotherapy-related granulocytopenia in a child with non-Hodgkin's lymphoma and a congenital abnormality of purine salvage.
Neutropenia
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
Nijmegen Breakage Syndrome
Therapy for non-Hodgkin lymphoma in children with primary immunodeficiency: analysis of 19 patients from the BFM trials.
Obesity
Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
Opportunistic Infections
Paraneoplastic Pemphigus Involving the Respiratory and Gastrointestinal Mucosae.
ornithine carbamoyltransferase deficiency
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
ornithine carbamoyltransferase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
Ornithine Carbamoyltransferase Deficiency Disease
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
Ornithine Carbamoyltransferase Deficiency Disease
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
Osteosarcoma
[USF1 Suppresses Expression of Fibrillar Type I, II, and III Collagen and pNP Adamts-3 in Osteosarcoma Cells].
Ovarian Cysts
Neoplasms associated with paraneoplastic pemphigus: a review with emphasis on non-hematologic malignancy and oral mucosal manifestations.
Ovarian Neoplasms
Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer.
Overweight
Erythrocyte adenosine deaminase and purine nucleoside phosphorylase activity in gout.
Pancreatic Neoplasms
hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer.
Pancreatic Neoplasms
Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer.
Pancreatic Neoplasms
Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer.
Pancreatic Neoplasms
Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy.
Paralysis
Bilateral phrenic-nerve paralysis treated by thoracoscopic diaphragmatic plication in a neonate.
Paralysis
Long-term course of phrenic nerve injury after cryoballoon ablation of atrial fibrillation.
Paralysis
Phrenic nerve palsy during ablation of atrial fibrillation using a 28-mm cryoballoon catheter: predictors and prevention.
Paralysis
Prevalence and Characteristics of Polyneuropathy in Atypical Parkinsonian Syndromes: An Explorative Study.
Paraplegia
Familial spastic paraplegia as the presenting manifestation in patients with purine nucleoside phosphorylase deficiency.
Paraplegia
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.
Paraproteinemias
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Paraproteinemias
Paraneoplastic pemphigus presenting with a single oral lesion.
Paraproteinemias
[Behavior of some enzymes of nucleoside catabolism in circulating lymphocytes during paraproteinemia]
Parasitemia
Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors.
Parasitic Diseases
Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors.
Paresis
Ipsilateral hemidiaphragmatic paresis after a supraclavicular and costoclavicular brachial plexus block: A randomised observer blinded study.
Parkinson Disease
Metabolites of Purine Nucleoside Phosphorylase (NP) in Serum Have the Potential to Delineate Pancreatic Adenocarcinoma.
Pediatric Obesity
Implementing family-based childhood obesity interventions.
Pemphigoid, Benign Mucous Membrane
Serum plakophilin-3 autoreactivity in paraneoplastic pemphigus.
Pemphigoid, Bullous
Bullous Diseases in Children: A Review of Clinical Features and Treatment Options.
Pemphigoid, Bullous
cDNA cloning of the 210-kDa paraneoplastic pemphigus antigen reveals that envoplakin is a component of the antigen complex.
Pemphigoid, Bullous
Detection and characterization of anti-envoplakin linker autoantibodies in paraneoplastic pemphigus using specific bead-based assay.
Pemphigoid, Bullous
Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.
Pemphigoid, Bullous
Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus.
Pemphigoid, Bullous
Human autoantibodies against HD1/plectin in paraneoplastic pemphigus.
Pemphigoid, Bullous
Mucosal dominant pemphigus vulgaris with anti-desmoplakin autoantibodies.
Pemphigoid, Bullous
Novel non-radioisotope immunoprecipitation studies indicate involvement of pemphigus vulgaris antigen in paraneoplastic pemphigus.
Pemphigoid, Bullous
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Pemphigoid, Bullous
Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3.
Pemphigoid, Bullous
Paraneoplastic pemphigus.
Pemphigoid, Bullous
Paraneoplastic pemphigus: a short review.
Pemphigoid, Bullous
Serum plakophilin-3 autoreactivity in paraneoplastic pemphigus.
Pemphigoid, Bullous
The members of the plakin family of proteins recognized by paraneoplastic pemphigus antibodies include periplakin.
Pemphigoid, Bullous
The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human.
Pemphigoid, Bullous
[Mechanism of alopecia in patients with paraneoplastic pemphigus]
Pemphigus
A nonfatal case and 2 fatal cases of paraneoplastic pemphigus: can a complement indirect immunofluorescent test help to identify fatal "group A" paraneoplastic pemphigus cases?
Pemphigus
Antibody titers to desmogleins 1 and 3 in a patient with paraneoplastic pemphigus associated with follicular dendritic cell sarcoma.
Pemphigus
Autoantibodies against desmocollins in European patients with pemphigus.
Pemphigus
Bullous Diseases in Children: A Review of Clinical Features and Treatment Options.
Pemphigus
cDNA cloning of the 210-kDa paraneoplastic pemphigus antigen reveals that envoplakin is a component of the antigen complex.
Pemphigus
Characterization of paraneoplastic pemphigus autoantigens by immunoblot analysis.
Pemphigus
Clinical and immunological findings in 104 cases of paraneoplastic pemphigus.
Pemphigus
Detection and characterization of anti-envoplakin linker autoantibodies in paraneoplastic pemphigus using specific bead-based assay.
Pemphigus
Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus.
Pemphigus
Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus.
Pemphigus
Genotyping of HLA-I and HLA-II alleles in Chinese patients with paraneoplastic pemphigus.
Pemphigus
Human autoantibodies against HD1/plectin in paraneoplastic pemphigus.
Pemphigus
Imaging characteristics of abdominal tumor in association with paraneoplastic pemphigus.
Pemphigus
Immunohistopathological study of autoimmune pemphigus. Lack of strictly specific histological and indirect immunofluorescence criteria for paraneoplastic pemphigus.
Pemphigus
Neoplasms associated with paraneoplastic pemphigus: a review with emphasis on non-hematologic malignancy and oral mucosal manifestations.
Pemphigus
Novel non-radioisotope immunoprecipitation studies indicate involvement of pemphigus vulgaris antigen in paraneoplastic pemphigus.
Pemphigus
Paraneoplastic pemphigus is associated with the DRB1*03 allele.
Pemphigus
Paraneoplastic Pemphigus Revealed by Anti-programmed Death-1 Pembrolizumab Therapy for Cutaneous Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa.
Pemphigus
Paraneoplastic pemphigus with circulating antibodies directed exclusively against the pemphigus vulgaris antigen desmoglein 3.
Pemphigus
Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3.
Pemphigus
Paraneoplastic pemphigus: a short review.
Pemphigus
Periplakin and envoplakin are target antigens in canine and human paraneoplastic pemphigus.
Pemphigus
Place of human amniotic membrane immunoblotting in the diagnosis of autoimmune bullous dermatoses.
Pemphigus
Recent advances in the study of the pathophysiology of pemphigus.
Pemphigus
Role of autoantibodies against the linker subdomains of envoplakin and periplakin in the pathogenesis of paraneoplastic pemphigus.
Pemphigus
Sensitivity and specificity of clinical, histologic, and immunologic features in the diagnosis of paraneoplastic pemphigus.
Pemphigus
Serum plakophilin-3 autoreactivity in paraneoplastic pemphigus.
Pemphigus
The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human.
Pemphigus
[Paraneoplastic pemphigus: Retrospective study of a case series].
Periodontal Diseases
Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.
Periodontal Diseases
The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models.
Periodontitis
Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.
Peripheral Nerve Injuries
Regenerative peripheral neuropathic pain: novel pathological pain, new therapeutic dimension.
Peripheral Nervous System Diseases
A prospective, open-label, multicentre study of pregabalin in the treatment of neuropathic pain in Latin America.
Peripheral Nervous System Diseases
Alcoholism, peripheral neuropathy (PNP) and cardiovascular autonomic neuropathy (CAN).
Peripheral Nervous System Diseases
Clinical relevance of neurological evaluation in patients suffering urinary retention in the absence of subvesical obstruction.
Peripheral Nervous System Diseases
Comparison of Long-term Complications in Patients on Haemodialysis and Peritoneal Dialysis Longer than 10 Years.
Peripheral Nervous System Diseases
Efficacy and toxicity profile of carfilzomib based regimens for treatment of multiple myeloma: A systematic review.
Peripheral Nervous System Diseases
Non-Pharmacological Management of Painful Peripheral Neuropathies: A Systematic Review.
Peripheral Nervous System Diseases
Peripheral neuropathies in patients with chronic obstructive pulmonary disease: a multicenter prevalence study.
Peripheral Nervous System Diseases
Systematic review and network meta-analysis of the efficacy and safety of lidocaine 700?mg medicated plaster vs. pregabalin.
Peripheral Nervous System Diseases
The MOBILE Study-A Phase IIa Enriched Enrollment Randomized Withdrawal Trial to Assess the Analgesic Efficacy and Safety of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Patients with Peripheral Neuropathic Pain.
Peroneal Neuropathies
Clinical Outcomes After Neurolysis for the Treatment of Peroneal Nerve Palsy: A Systematic Review and Meta-Analysis.
Peroneal Neuropathies
Peroneal neuropathy after weight loss.
Persistent Infection
Polynucleotide phosphorylase negatively controls spv virulence gene expression in Salmonella enterica.
Pheochromocytoma
Distribution of phosphoneuroprotein 14 (PNP 14) in vertebrates: its levels as determined by enzyme immunoassay.
Pneumonia
Pivotal Roles for Ribonucleases in Streptococcus pneumoniae Pathogenesis.
Pneumonia
Pneumococcal necrotizing pneumonia in Utah: does serotype matter?
Pneumonia
[Paraneoplastic pemphigus in a patient with non-Hodgkin lymphoma.]
Pneumonia, Pneumococcal
Pneumococcal necrotizing pneumonia in Utah: does serotype matter?
Pneumoperitoneum
A narrative review on the potential benefits and limitations of deep neuromuscular blockade.
Pneumoperitoneum
Clinical role of gasless laparoscopic adrenalectomy.
Pneumoperitoneum
Effects of laparoscopic pneumoperitoneum and changes in position on arterial pulse pressure wave-form: comparison between morbidly obese and normal-weight patients.
Pneumoperitoneum
Exploring for the Safer Ventilation Method in Laparoscopic Urologic Patients? Conventional or Low Tidal?
Polymyositis
Paraneoplastic pemphigus: a case of long-term survival associated with systemic lupus erythematosus and polymyositis.
Polyneuropathies
Cadmium: a possible etiological factor in peripheral polyneuropathy.
Polyneuropathies
Cryptogenetic polyneuropathies: an out-patient follow-up study.
Polyneuropathies
Electrical stimulation of the posterior tibial nerve reduces neuropathic pain in patients with polyneuropathy.
Polyneuropathies
Electromyography in Pediatric Population.
Polyneuropathies
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Polyneuropathies
Pharmacological Management of Painful Peripheral Neuropathies: A Systematic Review.
Polyneuropathies
Polyneuropathies in paediatrics.
Polyneuropathies
Polyneuropathy in Gaucher disease type 1 and 3 - a descriptive case series.
Polyneuropathies
Predictive variables for peripheral neuropathy in treated HIV type 1 infection revealed by machine learning.
Polyneuropathies
Prevalence and Characteristics of Polyneuropathy in Atypical Parkinsonian Syndromes: An Explorative Study.
Polyneuropathies
Thalidomide in consecutive multiple myeloma patients: single-center analysis on practical aspects, efficacy, side effects and prognostic factors with lower thalidomide doses.
Polyneuropathies
The effects of hyperventilation on axonal excitability parameters in patients with diabetes mellitus and polyneuropathy.
Polyneuropathies
VEMP responses are not affected in non-insulin-dependent diabetes mellitus patients with or without polyneuropathy.
Polyneuropathies
Vitamin D deficiency in patients with primary immune-mediated peripheral neuropathies.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
A comparison of balance control during stance and gait in patients with inflammatory and non-inflammatory polyneuropathy.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Isolated blood-cerebrospinal fluid barrier dysfunction: prevalence and associated diseases.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Ultrasound pattern sum score, homogeneity score and regional nerve enlargement index for differentiation of demyelinating inflammatory and hereditary neuropathies.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
[Antiganglioside antibodies: when, which and for what]
Porcine Reproductive and Respiratory Syndrome
Detection of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2, swine influenza virus and Aujeszky's disease virus in cases of porcine proliferative and necrotizing pneumonia (PNP) in Spain.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Adenosine deaminase and purine nucleoside phosphorylase in childhood lymphoblastic leukemia: relation with differentiation stage, in vitro drug resistance and clinical prognosis.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Characterization of purine nucleoside phosphorylase in leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Clinical relevance of in vitro drug resistance testing in childhood acute lymphoblastic leukemia: the state of the art.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Effects of 8-aminoguanosine on the toxicity of guanosine and deoxyguanosine for malignant and normal lymphoid cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Enzyme analysis of lymphoproliferative diseases: a useful addition to cell surface phenotyping.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Enzymes of purine metabolism and membrane phenotype in malignant cells of some leukemia patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Forodesine treatment and post-transplant graft-versus-host disease in two patients with acute leukemia: facilitation of graft-versus-leukemia effect?
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoblast purine pathway enzymes in B-cell acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Purine nucleoside phosphorylase activity in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Purine pathway enzyme abnormalities in acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Significance of enzyme markers as a part of multiple marker analysis in leukemia research.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The correlation of adenosine deaminase and purine nucleoside phosphorylase activities in human lymphocytes subpopulations and in various lymphoid malignancies.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Selective toxicity of deoxyguanosine and arabinosyl guanine for T-leukemic cells.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
The correlation of adenosine deaminase and purine nucleoside phosphorylase activities in human lymphocytes subpopulations and in various lymphoid malignancies.
Primary Immunodeficiency Diseases
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
Primary Immunodeficiency Diseases
Back to the beginnings: an autobiography.
Primary Immunodeficiency Diseases
EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children.
Primary Immunodeficiency Diseases
Importance of platelet-free preparations for evaluating lymphocyte nucleotide levels in inherited or acquired immunodeficiency syndromes.
Primary Immunodeficiency Diseases
Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma.
Primary Immunodeficiency Diseases
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.
Primary Immunodeficiency Diseases
The acquired immunodeficiency syndrome in infants and children.
Primary Immunodeficiency Diseases
The First Purine Nucleoside Phosphorylase Deficiency Patient Resembling IgA Deficiency and a Review of the Literature.
Primary Immunodeficiency Diseases
Therapy in adenosine deaminase and purine nucleoside phosphorylase deficient patients.
Primary Immunodeficiency Diseases
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Primary Immunodeficiency Diseases
[Congenital immunodeficiency syndrome with adenosine deaminase and purine nucleoside phosphorylase deficiencies (1)]
Propionic Acidemia
Direct-infusion based metabolomics unveils biochemical profiles of inborn errors of metabolism in cerebrospinal fluid.
Prostatic Neoplasms
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.
Prostatic Neoplasms
Gene-directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease.
Prostatic Neoplasms
Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus.
Prostatic Neoplasms
Production and release testing of ovine atadenovirus vectors.
Prostatic Neoplasms
Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer.
Prostatic Neoplasms
Targeted enzyme prodrug therapy for metastatic prostate cancer - a comparative study of L-methioninase, purine nucleoside phosphorylase, and cytosine deaminase.
Prostatic Neoplasms
Targeted expression of E. coli purine nucleoside phosphorylase and Fludara for prostate cancer therapy.
Prostatic Neoplasms
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer.
Protein Deficiency
Dietary modulation of thymic enzymes.
Protein-Losing Enteropathies
Paraneoplastic pemphigus associated with post-transplant lymphoproliferative disorder after small bowel transplantation.
Proteinuria
Effect of dietary protein restriction on renal purines and purine-metabolizing enzymes in adriamycin nephrosis in rats: a mechanism for protection against acute proteinuria involving xanthine oxidase inhibition.
Proteinuria
Panax notoginseng preparations as adjuvant therapy for diabetic kidney disease: a systematic review and meta-analysis.
Proteinuria
[Behavior of some enzymes of nucleoside catabolism in circulating lymphocytes during paraproteinemia]
Pruritus
Stimulation of sudomotor axon reflex mechanism by carbachol in healthy subjects and patients suffering from diabetic polyneuropathy.
Pseudolymphoma
Pyrimidine and purine activities in non-Hodgkin's lymphoma. Correlation with histological status and survival.
Psoriasis
Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
Psoriasis
[Metabolism of purine compounds in psoriasis]
Puberty, Delayed
4-Nitrophenol (PNP) inhibits the expression of estrogen receptor ? and disrupts steroidogenesis during the ovarian development in female rats.
Pulmonary Disease, Chronic Obstructive
Effects of peripheral neuropathy on exercise capacity and quality of life in patients with chronic obstructive pulmonary diseases.
Pulmonary Disease, Chronic Obstructive
Peripheral neuropathies in patients with chronic obstructive pulmonary disease: a multicenter prevalence study.
Pulmonary Disease, Chronic Obstructive
Sniff esophageal and nasopharyngeal pressures and maximal relaxation rates in patients with respiratory dysfunction.
purine-nucleoside phosphorylase deficiency
A canine model of induced purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma.
purine-nucleoside phosphorylase deficiency
A human purine nucleoside phosphorylase deficiency caused by a single base change.
purine-nucleoside phosphorylase deficiency
A new case of purine nucleoside phosphorylase deficiency: enzymologic, clinical, and immunologic characteristics.
purine-nucleoside phosphorylase deficiency
A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels.
purine-nucleoside phosphorylase deficiency
A patient with purine nucleoside phosphorylase deficiency: enzymological and metabolic aspects.
purine-nucleoside phosphorylase deficiency
A rat model of purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
A second case of inosine phosphorylase deficiency with severe T-cell abnormalities.
purine-nucleoside phosphorylase deficiency
A successful unrelated peripheral blood stem cell transplantation with reduced intensity-conditioning regimen in a patient with late-onset purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Absence of oroticaciduria in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
ADA and PNP deficiencies: how it all began.
purine-nucleoside phosphorylase deficiency
Adenosine deaminase and purine nucleoside phosphorylase deficiencies: evaluation of therapeutic interventions in eight patients.
purine-nucleoside phosphorylase deficiency
Adenosine deaminase and purine nucleoside phosphorylase deficiency: how they were discovered and what they may mean.
purine-nucleoside phosphorylase deficiency
Adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency in common variable immunodeficiency.
purine-nucleoside phosphorylase deficiency
Adenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.
purine-nucleoside phosphorylase deficiency
Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes.
purine-nucleoside phosphorylase deficiency
Altered erythrocyte nucleotide patterns are characteristic of inherited disorders of purine or pyrimidine metabolism.
purine-nucleoside phosphorylase deficiency
Altered purine and pyrimidine metabolism in erythrocytes with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
An approach to the restoration of T cell function in a purine nucleoside phosphorylase deficient patient.
purine-nucleoside phosphorylase deficiency
An erythrocyte Pr auto-antibody with sialoglycoprotein specificity in a patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
An unconditioned bone marrow transplantation in a child with purine nucleoside phosphorylase deficiency and its unique complication.
purine-nucleoside phosphorylase deficiency
An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome.
purine-nucleoside phosphorylase deficiency
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.
purine-nucleoside phosphorylase deficiency
Bilateral viral retinitis in a patient with immune deficiency because of purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Biochemical basis for lymphocyte dysfunction in adenosine deaminase and purine nucleoside phosphorylase deficiencies.
purine-nucleoside phosphorylase deficiency
Canine cyclic hematopoiesis is associated with abnormal purine and pyrimidine metabolism.
purine-nucleoside phosphorylase deficiency
Cellular immune deficiency with autoimmune hemolytic anemia in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Central nervous system dysfunction and erythrocyte guanosine triphosphate depletion in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Cerebellar abnormalities in purine nucleoside phosphorylase deficient mice.
purine-nucleoside phosphorylase deficiency
Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease.
purine-nucleoside phosphorylase deficiency
Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines.
purine-nucleoside phosphorylase deficiency
Clinico-biochemical and molecular studies of purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Cockayne's syndrome fibroblasts are characterized by hypersensitivity to deoxyguanosine and abnormal DNA precursor pool metabolism in response to deoxyguanosine or ultraviolet light.
purine-nucleoside phosphorylase deficiency
Combined familial adenosine deaminase and purine nucleoside phosphorylase deficiencies.
purine-nucleoside phosphorylase deficiency
Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression.
purine-nucleoside phosphorylase deficiency
Correction of purine nucleoside phosphorylase deficiency by retroviral-mediated gene transfer in mouse S49 T cell lymphoma: a model for gene therapy of T cell immunodeficiency.
purine-nucleoside phosphorylase deficiency
Correction of purine nucleoside phosphorylase deficiency by transplantation of allogeneic bone marrow from a sibling.
purine-nucleoside phosphorylase deficiency
Cross correction following haemopoietic stem cell transplant for purine nucleoside phosphorylase deficiency: engrafted donor-derived white blood cells provide enzyme to residual enzyme-deficient recipient cells.
purine-nucleoside phosphorylase deficiency
Crystal structure of human PNP complexed with hypoxanthine and sulfate ion.
purine-nucleoside phosphorylase deficiency
Decreased methionine synthesis in purine nucleoside-treated T and B lymphoblasts and reversal by homocysteine.
purine-nucleoside phosphorylase deficiency
Decreased phosphoribosylpyrophosphate as the basis for decreased purine synthesis during amino acid starvation of human lymphoblasts.
purine-nucleoside phosphorylase deficiency
Decreased S-adenosylhomocysteine hydrolase in inborn errors of purine metabolism.
purine-nucleoside phosphorylase deficiency
Deficiency of purine nucleoside phosphorylase activity in thymocytes from the immunodeficient diabetic BB rat.
purine-nucleoside phosphorylase deficiency
Deoxy GTP accumulates in thymocytes, but not in T or B lymphocytes in simulated PNP deficiency.
purine-nucleoside phosphorylase deficiency
Deoxyguanosine toxicity on lymphoid cells as a cause for immunosuppression in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Deoxyguanosine triphosphate as a possible toxic metabolite in the immunodeficiency associated with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Deoxyribonucleoside toxicity in adenosine deaminase and purine nucleoside phosphorylase deficiency: implications for the development of new immunosuppressive agents.
purine-nucleoside phosphorylase deficiency
Development and validation of a 2nd tier test for identification of purine nucleoside phosphorylase deficiency patients during expanded newborn screening by liquid chromatography-tandem mass spectrometry.
purine-nucleoside phosphorylase deficiency
Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots.
purine-nucleoside phosphorylase deficiency
Different pathways for deoxyguanosine toxicity in T-lymphocytes of various developmental stages.
purine-nucleoside phosphorylase deficiency
Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient.
purine-nucleoside phosphorylase deficiency
Direct-infusion based metabolomics unveils biochemical profiles of inborn errors of metabolism in cerebrospinal fluid.
purine-nucleoside phosphorylase deficiency
Disorders of purine and pyrimidine metabolism.
purine-nucleoside phosphorylase deficiency
Distribution of terminal deoxynucleotidyl transferase and purine degradative and synthetic enzymes in subpopulations of human thymocytes.
purine-nucleoside phosphorylase deficiency
Dysequilibrium/ataxic diplegia with immunodeficiency.
purine-nucleoside phosphorylase deficiency
Effects of purine nucleoside phosphorylase deficiency on thymocyte development.
purine-nucleoside phosphorylase deficiency
Erythrocyte GTP depletion in PNP deficiency presenting with haemolytic anaemia and hypouricaemia.
purine-nucleoside phosphorylase deficiency
Erythrocyte metabolism in purine nucleoside phosphorylase deficiency after enzyme replacement therapy by infusion of erythrocytes.
purine-nucleoside phosphorylase deficiency
Evidence for active purine nucleoside cycles in human mononuclear cells and cultured fibroblasts.
purine-nucleoside phosphorylase deficiency
Evidence that X-linked severe combined immunodeficiency is not a differentiation defect of T lymphocytes.
purine-nucleoside phosphorylase deficiency
Familial spastic paraplegia as the presenting manifestation in patients with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Fatal graft versus host disease after platelet transfusions in a child with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Genetic models of purine nucleoside phosphorylase deficiency in the mouse.
purine-nucleoside phosphorylase deficiency
GTP depletion and other erythrocyte abnormalities in inherited PNP deficiency.
purine-nucleoside phosphorylase deficiency
Guanine nucleotide metabolism in red blood cells: the metabolic basis for GTP depletion in HGPRT and PNP deficiency.
purine-nucleoside phosphorylase deficiency
Guanosine triphosphate catabolism in purine nucleoside phosphorylase deficient human B lymphoblastoid cells.
purine-nucleoside phosphorylase deficiency
High IL-18 (interferon-gamma inducing factor) concentration in a purine nucleoside phosphorylase deficient patient.
purine-nucleoside phosphorylase deficiency
High risk screening of adenosine deaminase and purine nucleoside phosphorylase deficiency in Japan.
purine-nucleoside phosphorylase deficiency
Identification of purine nucleoside phosphorylase deficiency in dried blood spots by a non-radiochemical assay using reversed-phase high-performance liquid chromatography.
purine-nucleoside phosphorylase deficiency
Immune deficiency due to adenosine deaminase and purine nucleoside phosphorylase deficiency: a simple diagnostic test.
purine-nucleoside phosphorylase deficiency
Immunodeficiency disease in animals.
purine-nucleoside phosphorylase deficiency
Immunofluorescence: a sensitive and rapid method for the detection of purine nucleoside phosphorylase in single cells.
purine-nucleoside phosphorylase deficiency
Immunological aberrations in purine nucleoside phosphorylase deficiencies.
purine-nucleoside phosphorylase deficiency
Immunological aspects of purine metabolism.
purine-nucleoside phosphorylase deficiency
Inborn errors of immunity associated with characteristic phenotypes.
purine-nucleoside phosphorylase deficiency
Incorporation of purine nucleosides in cultured fibroblasts from a patient with purine nucleoside phosphorylase deficiency and associated T-cell immunodeficiency.
purine-nucleoside phosphorylase deficiency
Infusion of Sibling Marrow in a Patient with Purine Nucleoside Phosphorylase Deficiency Leads to Split Mixed Donor Chimerism and Normal Immunity.
purine-nucleoside phosphorylase deficiency
Inhibition of purine nucleoside phosphorylase activity and of T-cell function with allopurinol-riboside.
purine-nucleoside phosphorylase deficiency
Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
purine-nucleoside phosphorylase deficiency
Inosine formation from hypoxanthine by intact erythrocytes and fibroblasts of an immunodeficient child with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Intracellular Delivery of Human Purine Nucleoside Phosphorylase by Engineered Diphtheria Toxin Rescues Function in Target Cells.
purine-nucleoside phosphorylase deficiency
Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro.
purine-nucleoside phosphorylase deficiency
Late diagnosis and correction of purine nucleoside phosphorylase deficiency with allogeneic bone marrow transplantation.
purine-nucleoside phosphorylase deficiency
Lentivirus gene therapy for purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Limited value of uric acid to creatinine ratios in estimating uric acid excretion.
purine-nucleoside phosphorylase deficiency
Liquid-chromatographic study of purine metabolism abnormalities in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Lupus manifestations in children with primary immunodeficiency diseases: Comprehensive phenotypic and genetic features and outcome.
purine-nucleoside phosphorylase deficiency
Lupus-Associated Functional Polymorphism in PNP Causes Cell Cycle Abnormalities and Interferon Pathway Activation in Human Immune Cells.
purine-nucleoside phosphorylase deficiency
Lymphocyte subpopulations in patients with various immunodeficiencies.
purine-nucleoside phosphorylase deficiency
Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: possible role of nucleoside kinase(s).
purine-nucleoside phosphorylase deficiency
Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.
purine-nucleoside phosphorylase deficiency
Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice.
purine-nucleoside phosphorylase deficiency
Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Molecular basis of a human purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Mononuclear cells in S-phase in a patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Mutations in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Novel Genetic Mutations in the First Swedish Patient with Purine Nucleoside Phosphorylase Deficiency and Clinical Outcome After Hematopoietic Stem Cell Transplantation with HLA-Matched Unrelated Donor.
purine-nucleoside phosphorylase deficiency
Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Novel mutations and hot-spots in patients with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Novel mutations of NP in two patients with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Nucleoside kinases in T and B lymphoblasts distinguished by autoradiography.
purine-nucleoside phosphorylase deficiency
Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.
purine-nucleoside phosphorylase deficiency
On the metabolism of allopurinol. Formation of allopurinol-1-riboside in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine.
purine-nucleoside phosphorylase deficiency
Partial Purine Nucleoside Phosphorylase Deficiency Helps Determine Minimal Activity Required for Immune and Neurological Development.
purine-nucleoside phosphorylase deficiency
Partial purine nucleoside phosphorylase deficiency. Studies of lymphocyte function.
purine-nucleoside phosphorylase deficiency
Persistent developmental delay despite successful bone marrow transplantation for purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Pharmacological and biochemical strategies to increase the accumulation of arabinofuranosylguanine triphosphatein primary human leukemia cells.
purine-nucleoside phosphorylase deficiency
Phosphorylation of deoxyguanosine by B and T lymphocytes: evidence against selective trapping of deoxyguanosine by T lymphocytes in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Polymorphism of S-adenosylhomocysteine hydrolase in Italy.
purine-nucleoside phosphorylase deficiency
Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni.
purine-nucleoside phosphorylase deficiency
Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli.
purine-nucleoside phosphorylase deficiency
Polynucleotide phosphorylase negatively controls spv virulence gene expression in Salmonella enterica.
purine-nucleoside phosphorylase deficiency
Prenatal diagnosis of purine nucleoside phosphorylase deficiency in the first and second trimesters of pregnancy.
purine-nucleoside phosphorylase deficiency
Prenatal exclusion of purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Primary immunodeficiency diseases associated with neurologic manifestations.
purine-nucleoside phosphorylase deficiency
Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Proposed explanation for S-adenosylhomocysteine hydrolase deficiency in purine nucleoside phosphorylase and hypoxanthine-guanine phosphoribosyltransferase-deficient patients.
purine-nucleoside phosphorylase deficiency
Purine metabolism and immunodeficiency: urinary purine excretion as a diagnostic screening test in adenosine deaminase and purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Purine nucleoside modulation of functions of human lymphocytes.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase activity and expression are upregulated in sites affected by periodontal disease.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency associated with a fatal lymphoproliferative disorder.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency associated with selective cellular immunodeficiency.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency with a novel PNP gene mutation: a first case report from India.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency with fatal course in two sisters.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency. Evidence for molecular heterogeneity in two families with enzyme-deficient members.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency. Measurement of variant protein in four families with enzyme-deficient members by an enzyme-linked immunosorbent assay.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: a molecular model for selective loss of T cell function.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: a mutation update.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: a new case report and identification of two novel mutations (Gly156A1a and Val217Ile), only one of which (Gly156A1a) is deleterious.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: altered kinetic properties of a mutant enzyme.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: biochemical properties and heterogeneity in two families.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency: improved metabolic and immunologic function with erythrocyte transfusions.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency; genetic studies in a Dutch family.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies.
purine-nucleoside phosphorylase deficiency
Purine nucleoside phosphorylases: properties, functions, and clinical aspects.
purine-nucleoside phosphorylase deficiency
Purinogenic immunodeficiency diseases: clinical features and molecular mechanisms.
purine-nucleoside phosphorylase deficiency
Rapid screening of high-risk patients for disorders of purine and pyrimidine metabolism using HPLC-electrospray tandem mass spectrometry of liquid urine or urine-soaked filter paper strips.
purine-nucleoside phosphorylase deficiency
Recent advances in understanding and managing adenosine deaminase and purine nucleoside phosphorylase deficiencies.
purine-nucleoside phosphorylase deficiency
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
purine-nucleoside phosphorylase deficiency
Red cell metabolism in purine nucleoside phosphorylase deficiency after enzyme replacement therapy.
purine-nucleoside phosphorylase deficiency
Sclerosing cholangitis and combination antifungal therapy for PNP deficiency patients.
purine-nucleoside phosphorylase deficiency
Screening for primary immunodeficiencies associated with purine nucleoside phosphorylase deficiency or adenosine deaminase deficiency.
purine-nucleoside phosphorylase deficiency
Severe Combined Immunodeficiency in Greek Children over a 20-Year Period : Rarity of ?(c)-Chain Deficiency (X-Linked) Type.
purine-nucleoside phosphorylase deficiency
Stroke in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Structures of human purine nucleoside phosphorylase complexed with inosine and ddI.
purine-nucleoside phosphorylase deficiency
Submolecular characterization of a mutant human purine-nucleoside phosphorylase.
purine-nucleoside phosphorylase deficiency
Successful HLA-identical bone marrow transplantation in a patient with PNP deficiency using busulfan and fludarabine for conditioning.
purine-nucleoside phosphorylase deficiency
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice.
purine-nucleoside phosphorylase deficiency
The acquired immunodeficiency syndrome in infants and children.
purine-nucleoside phosphorylase deficiency
The Broad Clinical Spectrum and Transplant Results of PNP Deficiency.
purine-nucleoside phosphorylase deficiency
The effect of deoxycytidine and tetrahydrouridine in purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
The effect of deoxyguanosine on human lymphocyte function. II. Analysis of the interference with B lymphocyte differentiation in vitro.
purine-nucleoside phosphorylase deficiency
The First Purine Nucleoside Phosphorylase Deficiency Patient Resembling IgA Deficiency and a Review of the Literature.
purine-nucleoside phosphorylase deficiency
The First Report of a Pregnancy in a Patient with Purine Nucleoside Phosphorylase Deficiency.
purine-nucleoside phosphorylase deficiency
The mechanism of inhibition and "reversal" of mitogen-induced lymphocyte activation in a model of purine-nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Therapy for non-Hodgkin lymphoma in children with primary immunodeficiency: analysis of 19 patients from the BFM trials.
purine-nucleoside phosphorylase deficiency
Therapy in adenosine deaminase and purine nucleoside phosphorylase deficient patients.
purine-nucleoside phosphorylase deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
purine-nucleoside phosphorylase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
purine-nucleoside phosphorylase deficiency
Upfront Enzyme Replacement via Erythrocyte Transfusions for PNP Deficiency.
purine-nucleoside phosphorylase deficiency
Urinary excretion of orotic acid, orotidine and other pyrimidines in a patient with purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Urinary purines in a patient with a severely defective T cell immunity and a purine nucleoside phosphorylase deficiency.
purine-nucleoside phosphorylase deficiency
Use of the integrated steady state rate equation to investigate product inhibition of human red cell adenosine deaminase and its relevance to immune dysfunction.
purine-nucleoside phosphorylase deficiency
[Congenital immunodeficiency syndrome with adenosine deaminase and purine nucleoside phosphorylase deficiencies (1)]
purine-nucleoside phosphorylase deficiency
[Congenital immunodeficiency with adenosine deaminase and purine nucleoside phosphorylase deficiency]
purine-nucleoside phosphorylase deficiency
[Escherichia coli K-12 mutants assimilating adenine via a new metabolic pathway]
purine-nucleoside phosphorylase deficiency
[Escherichia coli K-12 mutants capable of catabolizing purine nucleosides in the absence of purine nucleoside phosphorylase]
purine-nucleoside phosphorylase deficiency
[Hypouricemia and cellular immunodeficiency associated with purine-nucleoside phosphorylase deficiency]
purine-nucleoside phosphorylase deficiency
[Immune deficiencies secondary to enzymopathies]
purine-nucleoside phosphorylase deficiency
[Immune insufficiency in enzyme defects of purine metabolism]
purine-nucleoside phosphorylase deficiency
[PNP deficiency]
purine-nucleoside phosphorylase deficiency
[Purine nucleoside phosphorylase (PNP) deficiency]
purine-nucleoside phosphorylase deficiency
[Purine nucleoside phosphorylase (PNP)]
purine-nucleoside phosphorylase deficiency
[Purine nucleoside phosphorylase deficiency. Report of two cases]
purine-nucleoside phosphorylase deficiency
[Purine nucleoside phosphorylase deficiency]
purine-nucleoside phosphorylase deficiency
[Study on red cell enzymes and isoenzymes in patients with leukemia and myelodysplastic syndromes]
Purpura
Clinical features distinguishing lymphoma development in primary Sjögren's syndrome-A retrospective cohort study.
pyrimidine-nucleoside phosphorylase deficiency
Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency.
pyrimidine-nucleoside phosphorylase deficiency
On the metabolism of allopurinol. Formation of allopurinol-1-riboside in purine nucleoside phosphorylase deficiency.
pyrimidine-nucleoside phosphorylase deficiency
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase deficiency.
Quadriplegia
Late diagnosis and correction of purine nucleoside phosphorylase deficiency with allogeneic bone marrow transplantation.
Radiculopathy
Neuropathy in lymphoma: a relationship between the pattern of neuropathy, type of lymphoma and prognosis?
Reperfusion Injury
Difference in onset of warm ischemia and reperfusion injury between parenchymal and endothelial cells of the liver. Evaluation by purine nucleoside phosphorylase and hyaluronic acid.
Reperfusion Injury
No attenuation of ischemic and reperfusion injury in Kupffer cell-depleted, cold-preserved rat livers.
Respiratory Insufficiency
Long-term evaluation of phrenic nerve pacing for respiratory failure due to high cervical spinal cord injury.
Respiratory Insufficiency
Necrotizing tracheobronchitis with progressive airflow obstruction associated with paraneoplastic pemphigus.
Respiratory Insufficiency
Paraneoplastic pemphigus associated with bronchiolitis obliterans.
Respiratory Insufficiency
Paraneoplastic pemphigus associated with fatal bronchiolitis obliterans and appearance of anti-BP180 antibodies in the late stage of the disease.
Respiratory Insufficiency
Paraneoplastic pemphigus caused by an epithelioid leiomyosarcoma and associated with fatal respiratory failure.
Respiratory Insufficiency
Paraneoplastic pemphigus.
Respiratory Insufficiency
[A case of Charcot-Marie-Tooth disease (CMT) type 1 complicated by diabetes mellitus (DM) showing bilateral phrenic nerve palsy]
Retinal Degeneration
Attenuation of cadmium-induced testicular injury in metallothionein-III null mice.
Retinitis
Bilateral viral retinitis in a patient with immune deficiency because of purine nucleoside phosphorylase deficiency.
Sarcoma
Antibody titers to desmogleins 1 and 3 in a patient with paraneoplastic pemphigus associated with follicular dendritic cell sarcoma.
Sarcoma
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus.
Sarcoma
Conversion of 6-thioguanine to the nucleoside level by purine nucleoside phosphorylase of sarcoma 180 and sarcoma 180/TG ascites cells.
Sarcoma
Follicular dendritic cell sarcoma with paraneoplatic pemphigus: Rare case and a brief review of literature.
Sarcoma
Intra-abdominal inflammatory pseudotumor-like follicular dendritic cell sarcoma associated with paraneoplastic pemphigus: A case report and review of the literature.
Sarcoma
Paraneoplastic pemphigus and myasthenia gravis, associated with inflammatory pseudotumor-like follicular dendritic cell sarcoma: response to rituximab.
Sarcoma
Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma arising from Castleman's tumor.
Sarcoma
Paraneoplastic pemphigus associated with inflammatory myofibroblastic tumour of the mediastinum: A favourable response to treatment and review of the literature.
Sarcoma
Paraneoplastic pemphigus in a dog with splenic sarcoma.
Sarcoma
Paraneoplastic pemphigus.
Sarcoma
Purine nucleoside phosphorylase from human erythrocytes. 3. Inhibition by the inosine analog formycin B of the isolated enzyme and of nucleoside metabolism in intact erythrocytes and sarcoma 180 cells.
Sarcoma
[The activity of polynucleotide phosphorylase in polyribosomes of regenerating liver of adult rats, liver of newborn rats and in some reinoculated tumours]
Sarcoma 180
5-Iodoribose 1-phosphate, an analog of ribose 1-phosphate. Enzymatic synthesis and kinetic studies with enzymes of purine, pyrimidine, and sugar phosphate metabolism.
Sarcoma 180
Adenosine phosphyorylase activity as distinct from inosine-guanosine phosphorylase activity in Sarcoma 180 cells and rat liver.
Sarcoma 180
Conversion of 6-thioguanine to the nucleoside level by purine nucleoside phosphorylase of sarcoma 180 and sarcoma 180/TG ascites cells.
Sarcoma 180
Purine nucleoside phosphorylase from human erythrocytes. 3. Inhibition by the inosine analog formycin B of the isolated enzyme and of nucleoside metabolism in intact erythrocytes and sarcoma 180 cells.
Sarcoma, Avian
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models.
Sarcoma, Avian
Gene-directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease.
Sarcoma, Avian
Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer.
Schistosomiasis
Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.
Sepsis
Clinical Outcomes After Neurolysis for the Treatment of Peroneal Nerve Palsy: A Systematic Review and Meta-Analysis.
Sepsis
The role of the pediatric nurse practitioner in a neonatal unit.
Severe Combined Immunodeficiency
A Case with Purine Nucleoside Phosphorylase Deficiency Suffering from Late-Onset Systemic Lupus Erythematosus and Lymphoma.
Severe Combined Immunodeficiency
Capillary electrophoresis in diagnosis and monitoring of adenosine deaminase deficiency.
Severe Combined Immunodeficiency
Combined familial adenosine deaminase and purine nucleoside phosphorylase deficiencies.
Severe Combined Immunodeficiency
Direct evidence of autosomal recessive inheritance of Arg24 to termination codon in purine nucleoside phosphorylase gene in a family with a severe combined immunodeficiency patient.
Severe Combined Immunodeficiency
EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children.
Severe Combined Immunodeficiency
Exon skipping in purine nucleoside phosphorylase mRNA processing leading to severe immunodeficiency.
Severe Combined Immunodeficiency
Immunodeficiency, Motor Delay, and Hypouricemia Caused by a Novel Mutation of Purine Nucleoside Phosphorylase Gene in an Indian Infant.
Severe Combined Immunodeficiency
Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.
Severe Combined Immunodeficiency
Novel Genetic Mutations in the First Swedish Patient with Purine Nucleoside Phosphorylase Deficiency and Clinical Outcome After Hematopoietic Stem Cell Transplantation with HLA-Matched Unrelated Donor.
Severe Combined Immunodeficiency
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology.
Severe Combined Immunodeficiency
Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency.
Severe Combined Immunodeficiency
Purine nucleoside phosphorylase deficiency.
Severe Combined Immunodeficiency
Purinogenic immunodeficiency diseases: clinical features and molecular mechanisms.
Severe Combined Immunodeficiency
Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants.
Severe Combined Immunodeficiency
Successful HLA-identical bone marrow transplantation in a patient with PNP deficiency using busulfan and fludarabine for conditioning.
Severe Combined Immunodeficiency
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency.
Severe Combined Immunodeficiency
Two novel missense and frameshift mutations in exons 5 and 6 of the purine nucleoside phosphorylase (PNP) gene in a severe combined immunodeficiency (SCID) patient.
Severe Combined Immunodeficiency
Two novel mutations in a purine nucleoside phosphorylase (PNP)-deficient patient.
Severe Combined Immunodeficiency
[Purine nucleoside phosphorylase (PNP) deficiency]
Sexually Transmitted Diseases
Sexually Transmitted Infections and Children: What the PNP Should Know.
Shock, Septic
Anaerobic semi-fixed bed biofilm reactor (An-SFB-BR) for treatment of high concentration p-nitrophenol wastewater under shock loading conditions.
Skin Diseases
Serum plakophilin-3 autoreactivity in paraneoplastic pemphigus.
Skin Diseases, Vesiculobullous
Novel non-radioisotope immunoprecipitation studies indicate involvement of pemphigus vulgaris antigen in paraneoplastic pemphigus.
Sleep Apnea Syndromes
Polyneuropathy in Severely Obese Women Without Diabetes: Prevalence and Associated Factors.
Small Fiber Neuropathy
Polyneuropathy in levodopa-treated Parkinson's patients.
Spinal Cord Injuries
Total saponin extract, ginsenoside Rb1, and compound K alleviate peripheral and central neuropathic pain through estrogen receptors on rats.
Spinal Cord Injuries
Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications.
Spinal Dysraphism
Interaction between the splotch mutation and retinoic acid in mouse neural tube defects in vitro.
Spondylolisthesis
Predictive factors associated with neck pain in patients with cervical disc degeneration: A cross-sectional study focusing on Modic changes.
Squamous Cell Carcinoma of Head and Neck
Intratumoral generation of 2-fluoroadenine to treat solid malignancies of the head and neck.
Squamous Cell Carcinoma of Head and Neck
The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors.
Starvation
Abnormal physiological and molecular mutant phenotypes link chloroplast polynucleotide phosphorylase to the phosphorus deprivation response in Arabidopsis.
Starvation
Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Starvation
Altered proteoglycan synthesis via the false acceptor pathway can be dissociated from beta-D-xyloside inhibition of proliferation.
Starvation
Bioaugmentation for treating transient or continuous p-nitrophenol shock loads in an aerobic sequencing batch reactor.
Starvation
Degradation of ribosomal RNA during starvation: comparison to quality control during steady-state growth and a role for RNase PH.
Starvation
Integration of chloroplast nucleic acid metabolism into the phosphate deprivation response in Chlamydomonas reinhardtii.
Starvation
Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model.
Stevens-Johnson Syndrome
Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report.
Stevens-Johnson Syndrome
Paraneoplastic pemphigus with bronchiolitis obliterans in a child.
Stomatitis
A Case Report of Paraneoplastic Pemphigus Associated With Retroperitoneal Inflammatory Myofibroblastic Tumor.
Stomatitis
A Novel Use of Topical Ketamine for the Treatment of Oral Pemphigus: A Case Report.
Stomatitis
Clinical and immunopathological spectrum of paraneoplastic pemphigus.
Stomatitis
Intra-abdominal inflammatory pseudotumor-like follicular dendritic cell sarcoma associated with paraneoplastic pemphigus: A case report and review of the literature.
Stomatitis
Paraneoplastic pemphigus as a presentation of acute myeloid leukemia: Early diagnosis and remission.
Stomatitis
Paraneoplastic pemphigus associated with small lymphocytic lymphoma: A case report.
Stomatitis
Paraneoplastic Pemphigus in a 34-year-old.
Stomatitis
Paraneoplastic pemphigus in association with Castleman's disease.
Stomatitis
Paraneoplastic pemphigus with eosinophilic spongiosis and autoantibodies against desmocollins 2 and 3.
Stroke
Prehospital Notification Procedure Improves Stroke Outcome by Shortening Onset to Needle Time in Chinese Urban Area.
Stroke
Stroke in purine nucleoside phosphorylase deficiency.
Stroke
Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications.
Supranuclear Palsy, Progressive
Prevalence and Characteristics of Polyneuropathy in Atypical Parkinsonian Syndromes: An Explorative Study.
Synucleinopathies
Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study.
Tachypnea
The role of the pediatric nurse practitioner in a neonatal unit.
Thrombocytopenia
Inborn errors of immunity associated with characteristic phenotypes.
Thymoma
Activities of purine nucleotide metabolizing enzymes in human thymocytes and peripheral blood T lymphocytes: in vitro effect of thymic hormones.
Thymoma
Autoantibody production from a thymoma and a follicular dendritic cell sarcoma associated with paraneoplastic pemphigus.
Thymoma
Paraneoplastic pemphigus without antidesmoglein 3 or antidesmoglein 1 autoantibodies.
Thymoma
Paraneoplastic pemphigus.
Thyroiditis
Differential effects of 2'-deoxyguanosine on peripheral blood mononuclear cell proliferation in healthy donors and Hashimoto's thyroiditis patients.
Toxoplasmosis
Structural studies of PNP from Toxoplasma gondii.
Toxoplasmosis
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog.
Tremor
Neurobehavioral and clinical effects in workers exposed to CS(2).
Trichomonas Infections
Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis.
Tuberculosis
Assessing the role of deoD gene in Mycobacterium tuberculosis in vitro growth and macrophage infection.
Tuberculosis
Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir.
Tuberculosis
Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis.
Tuberculosis
Crystallographic structure of PNP from Mycobacterium tuberculosis at 1.9A resolution.
Tuberculosis
Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase.
Tuberculosis
Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis.
Tuberculosis
Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Tuberculosis
Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts.
Tuberculosis
Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity.
Tuberculosis
Structure and mechanism of Mycobacterium smegmatis polynucleotide phosphorylase.
Tuberculosis
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Tuberculosis
Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis.
Tuberculosis
Transition states and inhibitors of the purine nucleoside phosphorylase family.
Typhoid Fever
Selectively increased adenosine deaminase levels in T cells during typhoid fever.
Ulnar Neuropathies
Ulnar Neuropathy at Elbow in Patients With Type 2 Diabetes Mellitus.
Urinary Bladder Neoplasms
4-nitrophenol exposure in T24 human bladder cancer cells promotes proliferation, motilities, and epithelial-to-mesenchymal transition.
Urinary Bladder Neoplasms
Delivery of replication-competent retrovirus expressing Escherichia coli purine nucleoside phosphorylase increases the metabolism of the prodrug, fludarabine phosphate and suppresses the growth of bladder tumor xenografts.
Urinary Bladder Neoplasms
Host-mediated inhibition of rat bladder cancer growth by cyclophosphamide and purine salvage pathway-related enzyme activity of lymphocytes.
Urinary Bladder Neoplasms
Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer.
Urolithiasis
Urine Purine Metabolite Determination by UPLC-Tandem Mass Spectrometry.
Uterine Cervical Neoplasms
[Development of a conceptual model for interpretation of monitoring indicators of cancer screenings from the Italian National Prevention Plan].
Vaccinia
Impaired defense against vaccinia in a child with T-lymphocyte deficiency associated with inosine phosphorylase defect.
Vaccinia
Thymidine kinase-deleted vaccinia virus expressing purine nucleoside phosphorylase as a vector for tumor-directed gene therapy.
Vascular Diseases
Polyneuropathy and dementia in old age: common inflammatory and vascular parameters.
Vasculitis
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Virus Diseases
Crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with acyclovir.
Vitamin B 12 Deficiency
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
Vitamin B 12 Deficiency
Large-Fiber Neuropathy in Parkinson's Disease: Clinical, Biological, and Electroneurographic Assessment of a Romanian Cohort.
Vitamin D Deficiency
Vitamin D deficiency in patients with primary immune-mediated peripheral neuropathies.
Waldenstrom Macroglobulinemia
Paraneoplastic pemphigus treated with dexamethasone/ cyclophosphamide pulse therapy.
Werner Syndrome
Normal thermostability of hypoxanthine guanine phosphoribosyltransferase in erythrocytes from Werner's syndrome patients.
Wiskott-Aldrich Syndrome
Investigating the Variation of TREC/KREC in Combined Immunodeficiencies.
xanthine dehydrogenase deficiency
Thirteen years experience with selective screening for disorders in purine and pyrimidine metabolism.
xanthine oxidase deficiency
Two-dimensional thin-layer chromatography for the screening of disorders of purine and pyrimidine metabolism.
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2.4.2.1 purine-nucleoside phosphorylase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
