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Information on EC 2.4.1.B54 - 4,4'-diaponeurosporenoate glucosyltransferase and Organism(s) Staphylococcus aureus and UniProt Accession Q53590

for references in articles please use BRENDA:EC2.4.1.B54
preliminary BRENDA-supplied EC number
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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.B54 4,4'-diaponeurosporenoate glucosyltransferase
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This record set is specific for:
Staphylococcus aureus
UNIPROT: Q53590
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The taxonomic range for the selected organisms is: Staphylococcus aureus
The expected taxonomic range for this enzyme is: Staphylococcus aureus
Synonyms
CrtQ, NWMN_2463, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
NWMN_2463
locus name
PATHWAY SOURCE
PATHWAYS
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
4,4'-diaponeurosporenoate + UDP-alpha-D-glucose
glucosyl 4,4'-diaponeurosporenoate + UDP
show the reaction diagram
enzyme esterifies glucose at the C1'' position with the carboxyl group of 4,4'-diaponeurosporenic acid to yield glucosyl 4,4'-diaponeurosporenoate
-
-
?
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
member of the non-processive glycosyltransferase family
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
expression of staphyloxanthin pathway genes crtP, crtQ, crtM and crtN in Staphylococcus carnosus results in synthesis of glucosyl 4,4'-diaponeurosporenoate as a major product, with minor amounts of 4,4'-diaponeurosporenoate
physiological function
-
biosynthesis of triterpenoid carotenoids. The first C30 intermediate, 4,4'-diapophytoene, is converted via 4,4'-diapophytofluene, 4,4'-diapo-zeta-carotene, 4,4'-diaponeurosporene, 4,4'-diaponeurosporenal, 4,4'-diaponeurosporenoate, and glucosyl-diaponeurosporenoate to the major pigment staphyloxanthin
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
42500
x * 42500, calculated
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 42500, calculated
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Pelz, A.; Wieland, K.P.; Putzbach, K.; Hentschel, P.; Albert, K.; Gtz, F.
Structure and biosynthesis of staphyloxanthin from Staphylococcus aureus
J. Biol. Chem.
280
32493-32498
2005
Staphylococcus aureus (Q53590), Staphylococcus aureus ATCC 25904 (Q53590)
Manually annotated by BRENDA team
Marshall, J.H.; Wilmoth, G.J.
Proposed pathway of triterpenoid carotenoid biosynthesis in Staphylococcus aureus: evidence from a study of mutants
J. Bacteriol.
147
914-919
1981
Staphylococcus aureus
Manually annotated by BRENDA team