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Information on EC 2.4.1.86 - N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase

for references in articles please use BRENDA:EC2.4.1.86
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IUBMB Comments
The enzyme transfers galactose from UDP-alpha-D-galactose to the 3-position of substrates with a non-reducing terminal N-acetyl-beta-D-glucosamine (beta-GlcNAc) residue. It can act on both glycolipids and glycoproteins, generating a structure known as the type 1 histo-blood group antigen precursor.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
beta1,4GalT-4, galactosyltransferase, uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide, GalT-4, glucosaminylgalactosylglucosylceramide beta-galactosyltransferase, LcOseCer:GT, N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferaselceramide beta-galactosyltransferase, paragloboside synthase, UDP-Gal:LcOse3Cer beta1,4-galactosyltransferase, UDP-galactose:N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide 3-beta-D-galactosyltransferase, UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-galactose + N-acetyl-beta-D-glucosaminyl-R = UDP + beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-R
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