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Information on EC 2.4.1.70 - poly(ribitol-phosphate) alpha-N-acetylglucosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.70
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IUBMB Comments
Involved in the biosynthesis of poly(ribitol phosphate) teichoic acids in the cell wall of the bacterium Staphylococcus aureus. This enzyme adds an N-acetyl-alpha-D-glucosamine to the hydroxyl group at the 2 position of the ribitol phosphate units. cf. EC 2.4.1.355 [poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase].
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Word Map
  • 2.4.1.70
  • vegfr-2
  • lymphatic
  • sflt-1
  • angiogenic
  • lymphangiogenesis
  • fms-like
  • antiangiogenic
  • platelet-derived
  • microvessels
  • neovascularization
  • preeclampsia
  • kinase-1
  • receptor-3
  • lymphangiogenic
  • factor-c
  • anti-vegf
  • plgf-1
  • pdgfr-alpha
  • vegf-receptors
  • vegf-mediated
  • neuropilin-1
The expected taxonomic range for this enzyme is: Staphylococcus aureus
Synonyms
acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-poly(ribitol phosphate), poly(ribitol-phosphate) N-acetylglucosaminyltransferase, UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase, UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase, uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
n UDP-N-acetyl-alpha-D-glucosamine + 4-O-(D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = n UDP + 4-O-(2-N-acetyl-alpha-D-glucosaminyl-D-ribitylphospho)n-di[(2R)-1-glycerophospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
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