Disease on EC 2.4.1.65 - 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
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3-galactosyl-n-acetylglucosaminide 4-alpha-l-fucosyltransferase deficiency
Synthesis of {alpha}(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin.
Adenoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Breast Neoplasms
Fucosylation enhances the efficacy of adoptively transferred antigen-specific cytotoxic T lymphocytes.
Breast Neoplasms
Fucosyltransferase IV (FUT4) as an effective biomarker for the diagnosis of breast cancer.
Breast Neoplasms
Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer.
Breast Neoplasms
MicroRNA-106b targets FUT6 to promote cell migration, invasion, and proliferation in human breast cancer.
Breast Neoplasms
miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and ?1,3-fucosylated glycans.
Breast Neoplasms
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.
Breast Neoplasms
Specific detection of sialyl Lewis X determinant carried on the mucin GlcNAcbeta1-->6GalNAcalpha core structure as a tumor-associated antigen.
Breast Neoplasms
[Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis]
Carcinoma
alpha-2,3-Sialyltransferase type 3N and alpha-1,3-fucosyltransferase type VII are related to sialyl Lewis(x) synthesis and patient survival from lung carcinoma.
Carcinoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Carcinoma
C2-O-sLeX glycoproteins are E-selectin ligands that regulate invasion of human colon and hepatic carcinoma cells.
Carcinoma
Different expression levels of alpha3/4 fucosyltransferases and Lewis determinants in ovarian carcinoma tissues and cell lines.
Carcinoma
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation.
Carcinoma
Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue.
Carcinoma
Metastatic potential of human CX-1 colon adenocarcinoma cells is dependent on the expression of sialosyl Le(a) antigen.
Carcinoma
Neutrophil interactions with sialyl lewis X on human nonsmall cell lung carcinoma cells regulate invasive behavior.
Carcinoma
Role of sialosyl Lewis(a) in adhesion of colon cancer cells--the antisense RNA approach.
Carcinoma
Sialosyl-Le(x) expression defines invasive and metastatic properties of bladder carcinoma.
Carcinoma, Hepatocellular
Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells.
Carcinoma, Squamous Cell
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation.
Carcinoma, Squamous Cell
Fucosyltransferase IV enhances expression of MMP-12 stimulated by EGF via the ERK1/2, p38 and NF-?B pathways in A431 cells.
Colonic Neoplasms
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Colonic Neoplasms
The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
Colorectal Neoplasms
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Colorectal Neoplasms
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Colorectal Neoplasms
Evidence that the aberrant alpha 1-->2fucosyltransferase found in colorectal carcinoma may be encoded by Fuc-TIII (Le) gene.
Colorectal Neoplasms
Relationship Between Increased Fucosylation and Metastatic Potential in Colorectal Cancer.
Colorectal Neoplasms
The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
Colorectal Neoplasms
Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
Coronary Disease
Fucosyltransferase 3 polymorphism and atherothrombotic disease in the Framingham Offspring Study.
Eosinophilia
Synthesis of {alpha}(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin.
Esophageal Neoplasms
Upregulation of Fucosyltransferase 3, 8 and protein O-Fucosyltransferase 1, 2 genes in esophageal cancer stem-like cells (CSLCs).
Infections
Expression of a human alpha-1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Leb-containing glycoconjugates: a potential transgenic mouse model for studying Helicobacter pylori infection.
Infections
Use of flow cytometry to monitor infection and recombinant human alpha-1,3/4 fucosyltransferase production in baculovirus infected Sf9 cell cultures.
Infections
Viral vector-mediated delivery of competing glycosyltransferases modifies epitope expression cell specifically.
Inflammatory Bowel Diseases
[Association of inflammatory bowel disease with the polymorphisms and haplotypes of fucosyltransferase 3 gene].
Leukemia
Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines.
Leukemia
Fucosylation enhances the efficacy of adoptively transferred antigen-specific cytotoxic T lymphocytes.
Leukemia
Transcriptional regulation of expression of carbohydrate ligands for cell adhesion molecules in the selectin family.
Leukemia, Erythroblastic, Acute
Expression of GDP-L-Fuc: Gal(beta 1-4)GlcNAc-R (Fuc to GlcNAc) alpha-1,3-fucosyltransferase and its relationship to glycoprotein structure in a human erythroleukemia cell line, HEL.
Leukemia, T-Cell
Human T-cell leukemia virus-1 encoded Tax protein transactivates alpha 1-->3 fucosyltransferase Fuc-T VII, which synthesizes sialyl Lewis X, a selectin ligand expressed on adult T-cell leukemia cells.
Leukemia, T-Cell
Transcriptional regulation of expression of carbohydrate ligands for cell adhesion molecules in the selectin family.
Leukemia-Lymphoma, Adult T-Cell
Human T-cell leukemia virus-1 encoded Tax protein transactivates alpha 1-->3 fucosyltransferase Fuc-T VII, which synthesizes sialyl Lewis X, a selectin ligand expressed on adult T-cell leukemia cells.
Leukemia-Lymphoma, Adult T-Cell
Suppression of sialyl Lewis X expression and E-selectin-mediated cell adhesion in cultured human lymphoid cells by transfection of antisense cDNA of an alpha1-->3 fucosyltransferase (Fuc-T VII).
Liver Neoplasms
The Expression of Human alpha(1,3) Fucosyltransferase in Human Liver Cancer by in situ Hybridization.
Lung Neoplasms
Expression of alpha-1,3-fucosyltransferase type IV and VII genes is related to poor prognosis in lung cancer.
Lung Neoplasms
FUT4siRNA augments the chemosensitivity of non-small cell lung cancer to cisplatin through activation of FOXO1-induced apoptosis.
Lung Neoplasms
Neutrophil interactions with sialyl lewis X on human nonsmall cell lung carcinoma cells regulate invasive behavior.
Melanoma
A sialyl-Le(x)-negative melanoma cell line binds to E-selectin but not to P-selectin.
Melanoma
Fucosylation enhances the efficacy of adoptively transferred antigen-specific cytotoxic T lymphocytes.
Melanoma
Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cell proliferation by decreasing FUT4/LeY expression.
Melanoma
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells.
Neoplasm Metastasis
Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.
Neoplasm Metastasis
Fucosyltransferase IV (FUT4) as an effective biomarker for the diagnosis of breast cancer.
Neoplasm Metastasis
Metastatic potential of human CX-1 colon adenocarcinoma cells is dependent on the expression of sialosyl Le(a) antigen.
Neoplasm Metastasis
miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and ?1,3-fucosylated glycans.
Neoplasm Metastasis
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.
Neoplasm Metastasis
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
Neoplasm Metastasis
[Study on relationship of fucosyltransferase gene types in breast cancer with metastasis and prognosis]
Neoplasms
alpha-2,3-Sialyltransferase type 3N and alpha-1,3-fucosyltransferase type VII are related to sialyl Lewis(x) synthesis and patient survival from lung carcinoma.
Neoplasms
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Neoplasms
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Neoplasms
Cyclophosphamide-induced apoptosis in A431 cells is inhibited by fucosyltransferase IV.
Neoplasms
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation.
Neoplasms
Expression of alpha-(1,3)-fucosyltransferases which synthesize sialyl Le(x) and sialyl Le(a), the carbohydrate ligands for E- and P-selectins,in human malignant cell lines.
Neoplasms
Fucosyltransferase IV enhances expression of MMP-12 stimulated by EGF via the ERK1/2, p38 and NF-?B pathways in A431 cells.
Neoplasms
FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.
Neoplasms
Gene expression of fucosyl- and sialyl-transferases which synthesize sialyl Lewisx, the carbohydrate ligands for E-selectin, in human breast cancer.
Neoplasms
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Neoplasms
Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-?B/p65 signaling pathway to promote melanoma cell death.
Neoplasms
Neutrophil interactions with sialyl lewis X on human nonsmall cell lung carcinoma cells regulate invasive behavior.
Neoplasms
Overexpression of fucosyltransferase IV in A431 cell line increases cell proliferation.
Neoplasms
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells.
Neoplasms
Sialosyl-Le(x) expression defines invasive and metastatic properties of bladder carcinoma.
Neoplasms
The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.
Neoplasms
Tumor-associated macrophages promote Ezrin phosphorylation-mediated epithelial-mesenchymal transition in lung adenocarcinoma through FUT4/LeY up-regulation.
Osteosarcoma
Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis.
Pancreatic Neoplasms
Potential Biomarkers in Lewis Negative Patients With Pancreatic Cancer.
Polycystic Kidney Diseases
Family-based analysis identified CD2 as a susceptibility gene for primary open angle glaucoma in Chinese Han population.
Spondylitis, Ankylosing
Associations between fucosyltransferase 3 gene polymorphisms and ankylosing spondylitis: A case-control study of an east Chinese population.
Squamous Cell Carcinoma of Head and Neck
Human Ly-6 antigen E48 (Ly-6D) regulates important interaction parameters between endothelial cells and head-and-neck squamous carcinoma cells.
Tuberculosis
Fucosyltransferase IV and VII-directed selectin ligand function determines long-term survival in experimental tuberculosis.
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