Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 2.4.1.58 - lipopolysaccharide glucosyltransferase I

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
A penicillin-binding protein inhibits selection of colistin-resistant, lipooligosaccharide-deficient Acinetobacter baumannii.
Acute Coronary Syndrome
Expression of leukocyte adhesion-related glycosyltransferase genes in acute coronary syndrome patients.
Adenocarcinoma
A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis.
Alteration of lacto-series glycolipid glycosyltransferase activities in human colonic adenocarcinoma DLD-1 cells after culture in N,N-dimethylformamide-containing medium.
Glycosyltransferase and glycosidase activities in cultured human fetal and colonic adenocarcinoma cell lines.
Glycosyltransferase changes upon differentiation of CaCo-2 human colonic adenocarcinoma cells.
Glycosyltransferase levels in familial polyposis coli.
Intranuclear synthesized and native glycogen particles in human gastric cancer: ultrastructure and histochemistry.
Adenoma
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Adenomatous Polyposis Coli
Glycosyltransferase levels in familial polyposis coli.
Alzheimer Disease
GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3?/?-catenin signaling.
[Alzheimer's disease and glycosyltransferase]
Amyotrophic Lateral Sclerosis
Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration.
Mutation screening and burden analysis of GLT8D1 in Chinese patients with amyotrophic lateral sclerosis.
Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis.
Arthritis, Rheumatoid
Production of soluble human alpha3-fucosyltransferase (FucT VII) by membrane targeting and in vivo proteolysis.
Astrocytoma
Circulating microRNAs as Biomarkers for Pediatric Astrocytomas.
Bacteremia
ArcA-regulated glycosyltransferase Lic2B promotes complement evasion and pathogenesis of nontypeable Haemophilus influenzae.
Brain Neoplasms
Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes.
Breast Neoplasms
Control of metastasis by Asn-linked, beta1-6 branched oligosaccharides in mouse mammary cancer cells.
Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy.
Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.
Overexpression of ?2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.
Post-translational and transcriptional regulation of glycolipid glycosyltransferase genes in apoptotic breast carcinoma cells: VII. Studied by DNA-microarray after treatment with L: -PPMP.
Prognostic utility of glycosyltransferase expression in breast cancer.
Regulation of glycosyltransferase genes in apoptotic breast cancer cells induced by L: -PPMP and cisplatin.
Role of N-acetylgalactosaminyltransferase 6 in early tumorigenesis and formation of metastasis.
Targeted glycoproteomic identification of biomarkers for human breast carcinoma.
The exostosin family of glycosyltransferases: mRNA expression profiles and heparan sulphate structure in human breast carcinoma cell lines.
Calcinosis
Absence of intraepidermal glycosyltransferase ppGalNac-T3 expression in familial tumoral calcinosis.
Identification of a recurrent mutation in GALNT3 demonstrates that hyperostosis-hyperphosphatemia syndrome and familial tumoral calcinosis are allelic disorders.
Polypeptide GalNAc-transferase T3 and familial tumoral calcinosis. Secretion of fibroblast growth factor 23 requires O-glycosylation.
Carcinogenesis
Elevation of alpha2-->6 sialyltransferase and alpha1-->2 fucosyltransferase activities in human choriocarcinoma.
GALNT6 Stabilizes GRP78 Protein by O-glycosylation and Enhances its Activity to Suppress Apoptosis Under Stress Condition.
Over-expression of ST3Gal-I promotes mammary tumorigenesis.
Specific N-glycans of Hepatocellular Carcinoma Cell Surface and the Abnormal Increase of Core-?-1, 6-fucosylated Triantennary Glycan via N-acetylglucosaminyltransferases-IVa Regulation.
Synthetic self-adjuvanting glycopeptide cancer vaccines.
Targeted glycoproteomic identification of biomarkers for human breast carcinoma.
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Traveling for the glycosphingolipid path.
Carcinoma
A novel member of the glycosyltransferase family, beta 3 Gn-T2, highly downregulated in invasive human bladder transitional cell carcinomas.
ABO blood-group antigens in oral cancer.
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Blood group ABO and Lewis antigens in bladder tumors: correlation between glycosyltransferase activity and antigen expression.
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Expression of sialyl-Tn epitopes on beta1 integrin alters epithelial cell phenotype, proliferation and haptotaxis.
Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Regulations of glycolipid: XI. glycosyltransferase (GSL: GLTs) genes involved in SA-LeX and related GSLs biosynthesis in carcinoma cells by Biosimilar apoptotic agents: potential anticancer drugs.
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells.
Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
Carcinoma, Ehrlich Tumor
Glycosyltransferase activities of Ehrlich ascites tumor cells: detection, isolation, and characterization using oligosaccharide-Synsorb beads.
Carcinoma, Hepatocellular
Glycosylation reactions and tumor establishment: modulation by vitamin A.
Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells.
Upregulation of OGT by Caveolin-1 promotes hepatocellular carcinoma cell migration and invasion.
Carcinoma, Ovarian Epithelial
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
Carcinoma, Papillary
Immunohistochemical study of type-1 blood antigen expressions in thyroid tumors: the significance for papillary carcinomas.
Carcinoma, Transitional Cell
A novel member of the glycosyltransferase family, beta 3 Gn-T2, highly downregulated in invasive human bladder transitional cell carcinomas.
Blood group ABO and Lewis antigens in bladder tumors: correlation between glycosyltransferase activity and antigen expression.
Cardiomyopathies
Reduced myocyte complex N-glycosylation causes dilated cardiomyopathy.
Chancroid
Construction and characterization of Haemophilus ducreyi lipooligosaccharide (LOS) mutants defective in expression of heptosyltransferase III and beta1,4-glucosyltransferase: identification of LOS glycoforms containing lactosamine repeats.
Cholera
Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling.
[Development of multiplex real time PCR methodology for better identification and discrimination of Vibrio cholerae and O139 serotype.]
Chondrosarcoma
Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.
Chronic Periodontitis
In Porphyromonas gingivalis VimF is involved in gingipain maturation through the transfer of galactose.
Classical Swine Fever
Novel thioglycosyl analogs of glycosyltransferase substrates as antiviral compounds against classical swine fever virus and hepatitis C virus.
Colitis
Function of the glycosyltransferase GnT-V in colitis.
Intestinal goblet cells and mucins in health and disease: recent insights and progress.
Colonic Neoplasms
Alterations in glycosyltransferase activity in human colon cancer.
Alterations of O-glycan biosynthesis in human colon cancer tissues.
Clinical relevance of the differential expression of the glycosyltransferase gene GCNT3 in colon cancer.
Glycosyltransferase B4GALNT2 as a Predictor of Good Prognosis in Colon Cancer: Lessons from Databases.
Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Synthesis of O-glycan core 3: characterization of UDP-GlcNAc: GalNAc-R beta 3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines.
Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms.
Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
Colorectal Neoplasms
Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases.
Altered mRNA expression of specific molecular species of fucosyl- and sialyl-transferases in human colorectal cancer tissues.
Correlation between glycoconjugate expression and fucosyltransferase activity in human colorectal carcinoma.
Glycosyltransferase B4GALNT2 as a Predictor of Good Prognosis in Colon Cancer: Lessons from Databases.
Glycosyltransferase Gene Expression Identifies a Poor Prognostic Colorectal Cancer Subtype Associated with Mismatch Repair Deficiency and Incomplete Glycan Synthesis.
Overexpression of sialyltransferase CMP-sialic acid:Galbeta1,3GalNAc-R alpha6-Sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Reconstitution of TGFBR2 in HCT116 colorectal cancer cells causes increased LFNG expression and enhanced N-acetyl-d-glucosamine incorporation into Notch1.
The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance.
Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression.
Up-regulation of a set of glycosyltransferase genes in human colorectal cancer.
Communicable Diseases
Development and Validation of a Universal High-Throughput UDP-Glycosyltransferase Assay with a Time-Resolved FRET Signal.
Congenital Disorders of Glycosylation
Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Deficiency in COG5 causes a moderate form of congenital disorders of glycosylation.
Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases.
Crigler-Najjar Syndrome
Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II.
Cystic Fibrosis
Glycosylation of VSV glycoprotein is similar in cystic fibrosis, heterozygous carrier, and normal human fibroblasts.
Intestinal mucins from cystic fibrosis mice show increased fucosylation due to an induced Fucalpha1-2 glycosyltransferase.
Demyelinating Diseases
The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination.
Dental Caries
Inhibition of Streptococcus mutans polysaccharide synthesis by molecules targeting glycosyltransferase activity.
Dental Plaque
Presence of an extracellular glycosyltransferase in human dental plaque.
Relationship between Candida albicans and Streptococcus mutans in early childhood caries, evaluated by quantitative PCR.
Diabetes Mellitus, Experimental
The effects of streptozotocin diabetes on the activities of rat liver glycosyltransferases.
Diabetes Mellitus, Type 1
Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population.
Diabetes Mellitus, Type 2
Altered N-glycosylation profiles as potential biomarkers and drug targets in diabetes.
Protein Glycosylation in Diabetes.
Endocarditis
Capsule loss or death: The position of mutations among capsule genes sways the destiny of Streptococcus suis.
Escherichia coli Infections
Susceptibility of infant mice to F5 (K99) E. coli infection: differences in glycosyltransferase activities in intestinal mucosa of inbred CBA and DBA/2 strains.
Exostoses
A Novel Nonsense Mutation in the EXT2 Gene Identified in a Family with Hereditary Multiple Osteochondromas.
The molecular and cellular basis of exostosis formation in hereditary multiple exostoses.
Exostoses, Multiple Hereditary
A family with limb girdle muscular dystrophy type 1B and multiple exostoses.
Assessing the general population frequency of rare coding variants in the EXT1 and EXT2 genes previously implicated in hereditary multiple exostoses.
Familial Solitary Chondrosarcoma Resulting from Germline EXT2 Mutation.
Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses.
Fatty Liver
Mechanism of the effect of glycosyltransferase GLT8D2 on fatty liver.
Fibrosarcoma
Regulation of homotypic cell-cell adhesion by branched N-glycosylation of N-cadherin extracellular EC2-3 domains.
Fusariosis
Engineering Flax with the GT Family 1 Solanum sogarandinum Glycosyltransferase SsGT1 Confers Increased Resistance to Fusarium Infection.
Gastroenteritis
Lack of functional P-selectin ligand exacerbates Salmonella serovar typhimurium infection.
Genetic Diseases, Inborn
Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses.
Gilbert Disease
Contribution of two missense mutations (G71R and Y486D) of the bilirubin UDP glycosyltransferase (UGT1A1) gene to phenotypes of Gilbert's syndrome and Crigler-Najjar syndrome type II.
Glioblastoma
Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients.
Role of glycosyltransferase PomGnT1 in glioblastoma progression.
Glioma
Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients.
Effect of retinoic acid on two glycosyltransferase activities in C6 cultured glioma cells.
High expression of ?3GnT8 is associated with the metastatic potential of human glioma.
[Molecular mechanism of antisense glycosyltransferase oligonucleotide inhibiting human gliomas cell line SWO-38]
Glomerulonephritis, IGA
A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.
Interaction between variants of two glycosyltransferase genes in IgA nephropathy.
Protein glycosylation: chaperone mutation in Tn syndrome.
Glucose Intolerance
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Graft vs Host Disease
GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.
Gram-Negative Bacterial Infections
Septal Class A Penicillin-Binding Protein Activity and ld-Transpeptidases Mediate Selection of Colistin-Resistant Lipooligosaccharide-Deficient Acinetobacter baumannii.
Heart Failure
Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy.
Hepatitis C
Novel thioglycosyl analogs of glycosyltransferase substrates as antiviral compounds against classical swine fever virus and hepatitis C virus.
Herpes Simplex
Inhibition of protein deacetylation augments herpes simplex virus type 1-activated transcription of host fucosyltransferase genes associated with virus-induced sLex expression.
HIV Infections
Decrease of Lewis frequency in HIV-infected patients: possible competition of fucosylated antigens with HIV for binding to DC-SIGN.
Hyperglycemia
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Hyperinsulinism
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Hyperphosphatemia
Familial Tumoral Calcinosis: From Characterization of a Rare Phenotype to the Pathogenesis of Ectopic Calcification.
Hypersensitivity
Custard Apple Allergy with Glycosyltransferase as the Allergen Involved.
The N-Terminus of Vps74p Is Essential for the Retention of Glycosyltransferases in the Golgi but Not for the Modulation of Apical Polarized Growth in Saccharomyces cerevisiae.
Infections
Aberrant O-linked oligosaccharide biosynthesis in lymphocytes and platelets from patients with the Wiskott-Aldrich syndrome.
Amsacta moorei entomopoxvirus encodes a functional heparin-binding glycosyltransferase (AMV248).
Caenorhabditis elegans bacterial pathogen resistant bus-4 mutants produce altered mucins.
Comprehensive transcriptome profiling in tomato reveals a role for glycosyltransferase in Mi-mediated nematode resistance.
Construction and characterization of Haemophilus ducreyi lipooligosaccharide (LOS) mutants defective in expression of heptosyltransferase III and beta1,4-glucosyltransferase: identification of LOS glycoforms containing lactosamine repeats.
Elevated expression of bisecting N-acetylglucosaminyltransferase-III gene in a human fetal hepatocyte cell line by hepatitis B virus.
Glycophenotypic alterations induced by Pteridium aquilinum in mice gastric mucosa: synergistic effect with Helicobacter pylori infection.
Glycosylation-related gene expression profiling in brain and spleen of scrapie-affected mouse.
Hepatitis C Virus-Induced FUT8 Causes 5-FU Drug Resistance in Human Hepatoma Huh7.5.1 Cells.
Host glycosylation pathways and the unfolded protein response contribute to the infection by Francisella.
Identification of transient glycosylation alterations of sialylated mucin oligosaccharides during infection by the rat intestinal parasite Nippostrongylus brasiliensis.
In vitro expression of bovine opsin using recombinant baculovirus: the role of glutamic acid (134) in opsin biosynthesis and glycosylation.
Lack of functional P-selectin ligand exacerbates Salmonella serovar typhimurium infection.
NeuAc alpha 2,3gal-glycoconjugate expression determines cell susceptibility to the porcine rubulavirus LPMV.
Polymorphisms in the Chlamydia trachomatis cytotoxin locus associated with ocular and genital isolates.
RNA and Sugars, Unique Properties of Bacteriophages Infecting Multidrug Resistant Acinetobacter radioresistens Strain LH6.
Role of Glycosylation/Deglycolysation Processes in Francisella tularensis Pathogenesis.
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Suppression of Alternative Lipooligosaccharide Glycosyltransferase Activity by UDP-Galactose Epimerase Enhances Murine Lung Infection and Evasion of Serum IgM.
Susceptibility of infant mice to F5 (K99) E. coli infection: differences in glycosyltransferase activities in intestinal mucosa of inbred CBA and DBA/2 strains.
The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design.
Vaccination of Elk (Cervus canadensis) with Brucella abortus Strain RB51 Overexpressing Superoxide Dismutase and Glycosyltransferase Genes Does Not Induce Adequate Protection against Experimental Brucella abortus Challenge.
Leukemia
A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data.
Chronic lymphatic leukemia (CLL): cell surface changes detected by lectin binding and their relation to altered glycosyltransferase activity.
Glycosyltransferase alterations are cell type related when human promyelocytic leukemia (HL-60) cells are treated with various inducers of differentiation.
Leukemia-induced alterations of serum glycosyltransferase enzymes.
Tunicamycin-induced neutrophil extracellular trap (NET)-like structures in cultured human myeloid cell lines.
Leukemia, Erythroblastic, Acute
Alterations in glycosyltransferase levels in mouse erythroleukemia cells during erythrodifferentiation and cell growth.
Leukemia, Lymphocytic, Chronic, B-Cell
Chronic lymphatic leukemia (CLL): cell surface changes detected by lectin binding and their relation to altered glycosyltransferase activity.
Leukemia, Lymphoid
Single glycosyltransferase, core 2 beta1-->6-N-acetylglucosaminyltransferase, regulates cell surface sialyl-Lex expression level in human pre-B lymphocytic leukemia cell line KM3 treated with phorbolester.
Leukemia, Myeloid
Interleukin-3-associated expression of gangliosides in mouse myelogenous leukemia NFS60 cells introduced with interleukin-3 gene: expression of ganglioside GD1a and key involvement of CMP-NeuAc:lactosylceramide alpha 2-->3-sialyltransferase in GD1a expression.
NOTCH activation promotes glycosyltransferase expression in human myeloid leukemia cells.
Possible role of ceramide in defining structure and function of membrane glycolipids.
Leukemia, Myeloid, Acute
Leukemia-induced alterations of serum glycosyltransferase enzymes.
lipopolysaccharide glucosyltransferase i deficiency
In vitro analysis of glial cell function in ganglioside-deficient mice.
Non-redundant function of dystroglycan and {beta}1 integrins in radial sorting of axons.
Liver Neoplasms
[Effects of Compound Aconitum Polysaccharide on Glycosylation of Tumor Cells].
Lung Neoplasms
Ganglioside G(D2) in small cell lung cancer cell lines: enhancement of cell proliferation and mediation of apoptosis.
Glycolipid glycosyltransferase levels in surgical and transplanted human lung cancers.
Lymphoma
Haploinsufficiency of C2GnT-I glycosyltransferase renders T lymphoma cells resistant to cell death.
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.
Possible role of ceramide in defining structure and function of membrane glycolipids.
Lymphoma, B-Cell
Overexpression of GLT1D1 induces immunosuppression through glycosylation of PD-L1 and predicts poor prognosis in B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Overexpression of GLT1D1 induces immunosuppression through glycosylation of PD-L1 and predicts poor prognosis in B-cell lymphoma.
Malaria
Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.
Malaria, Falciparum
Common variation in the ABO glycosyltransferase is associated with susceptibility to severe Plasmodium falciparum malaria.
Malformations of Cortical Development, Group II
Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1.
Melanoma
Aberrant Glycosylation in Cancer: A Novel Molecular Mechanism Controlling Metastasis.
Analysis of melanoma cells stably transfected with beta 1,4GalNAc transferase (GM2/GD2 synthase) cDNA: relative glycosyltransferase levels play a dominant role in determining ganglioside expression.
Beta1,6-branched oligosaccharides regulate melanin content and motility in macrophage-melanoma fusion hybrids.
Glycosylation pathways in the biosynthesis of gangliosides in melanoma and neuroblastoma cells: relative glycosyltransferase levels determine ganglioside patterns.
Loss of GCNT2/I-branched glycans enhances melanoma growth and survival.
Relationship of glycosyltransferases and mRNA levels to ganglioside expression in neuroblastoma and melanoma cells.
UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor ? and interleukin 6.
[Sialyltransferase in human malignant melanoma]
Meningioma
Glycosyltransferase activities in human meningiomas. Preliminary results.
Metabolic Diseases
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Multiple Sclerosis
Activity levels of a beta1,6 N-acetylglucosaminyltransferase in lymphomonocytes from multiple sclerosis patients.
Muscular Diseases
A family with limb girdle muscular dystrophy type 1B and multiple exostoses.
Muscular Dystrophies
A rapid PCR method for genotyping the Large(myd) mouse, a model of glycosylation-deficient congenital muscular dystrophy.
Aberrant neuromuscular junctions and delayed terminal muscle fiber maturation in alpha-dystroglycanopathies.
An immunological analysis of dystroglycan subunits: lessons learned from a small cohort of non-congenital dystrophic patients.
Animal models for genetic neuromuscular diseases.
B3GALNT2-Related Dystroglycanopathy: Expansion of the Phenotype with Novel Mutation Associated with Muscle-Eye-Brain Disease, Walker-Warburg Syndrome, Epileptic Encephalopathy-West Syndrome, and Sensorineural Hearing Loss.
Biochemical and ultrastructural evidence of endoplasmic reticulum stress in LGMD2I.
Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of ?-dystroglycan.
Comparative Proteomic Profiling of Dystroglycan-Associated Proteins in Wild Type, mdx, and Galgt2 Transgenic Mouse Skeletal Muscle.
Congenital muscular dystrophies involving the O-mannose pathway.
Defective glycosylation in congenital muscular dystrophies.
Defective glycosylation of ?-dystroglycan contributes to podocyte flattening.
Defects in tangential neuronal migration of pontine nuclei neurons in the Largemyd mouse are associated with stalled migration in the ventrolateral hindbrain.
Dictyostelium gnt15 encodes a protein with similarity to LARGE and plays an essential role in development.
Dmdmdx/Largemyd: a new mouse model of neuromuscular diseases useful for studying physiopathological mechanisms and testing therapies.
From "glycosyltransferase" to "congenital muscular dystrophy": integrating knowledge from NCBI Entrez Gene and the Gene Ontology.
Glycomic analyses of mouse models of congenital muscular dystrophy.
Glycosylation defects in inherited muscle disease.
Homozygosity Mapping and Whole-Genome Sequencing Links a Missense Mutation in POMGNT1 to Autosomal Recessive Retinitis Pigmentosa.
LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies.
Large is required for normal astrocyte migration and retinal vasculature development.
Limb-girdle muscular dystrophy 2I: phenotypic variability within a large consanguineous Bedouin family associated with a novel FKRP mutation.
Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy.
Missense mutations in ?-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome.
Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1.
Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse.
Mutation of Large, which encodes a putative glycosyltransferase, in an animal model of muscular dystrophy.
Mutations in the human LARGE gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan.
Non-redundant function of dystroglycan and {beta}1 integrins in radial sorting of axons.
Sarcolemma instability during mechanical activity in Largemyd cardiac myocytes with loss of dystroglycan extracellular matrix receptor function.
Skeletal, cardiac and tongue muscle pathology, defective retinal transmission, and neuronal migration defects in the Large(myd) mouse defines a natural model for glycosylation-deficient muscle - eye - brain disorders.
The gene for a novel glycosyltransferase is mutated in congenital muscular dystrophy MDC1C and limb girdle muscular dystrophy 2I.
Transgenic overexpression of LARGE induces ?-dystroglycan hyperglycosylation in skeletal and cardiac muscle.
Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies.
Zebrafish models for human FKRP muscular dystrophies.
Muscular Dystrophies, Limb-Girdle
An immunological analysis of dystroglycan subunits: lessons learned from a small cohort of non-congenital dystrophic patients.
Biochemical and ultrastructural evidence of endoplasmic reticulum stress in LGMD2I.
Protein homeostasis in LGMDR9 (LGMD2I) - The role of ubiquitin-proteasome and autophagy-lysosomal system.
The gene for a novel glycosyltransferase is mutated in congenital muscular dystrophy MDC1C and limb girdle muscular dystrophy 2I.
Muscular Dystrophy, Duchenne
Congenital muscular dystrophies involving the O-mannose pathway.
Mycoplasma Infections
Expression and characterization of a mycoplasma genitalium glycosyltransferase in membrane glycolipid biosynthesis. potential target against mycoplasma infections.
Myositis
Journey into muscular dystrophies caused by abnormal glycosylation.
Myositis, Inclusion Body
Journey into muscular dystrophies caused by abnormal glycosylation.
Myxoma
Post-translational modification of the myxoma-virus anti-inflammatory serpin SERP-1 by a virally encoded sialyltransferase.
Neoplasm Metastasis
Aberrant Glycosylation in Cancer: A Novel Molecular Mechanism Controlling Metastasis.
Aberrant Glycosylation Promotes Lung Cancer Metastasis through Adhesion to Galectins in the Metastatic Niche.
Caveolin-1 promotes Rfng expression via Erk-Jnk-p38 signaling pathway in mouse hepatocarcinoma cells.
Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer.
Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer.
Glycosylation reactions and tumor establishment: modulation by vitamin A.
Physiological roles of N-acetylglucosaminyltransferase V(GnT-V) in mice.
Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer.
Specific N-glycans of Hepatocellular Carcinoma Cell Surface and the Abnormal Increase of Core-?-1, 6-fucosylated Triantennary Glycan via N-acetylglucosaminyltransferases-IVa Regulation.
Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer.
Upregulation of N-acetylglucosaminyltransferase-V by heparin-binding EGF-like growth factor induces keratinocyte proliferation and epidermal hyperplasia.
Upregulation of OGT by Caveolin-1 promotes hepatocellular carcinoma cell migration and invasion.
[Tumor metastases and adhesion molecules carbohydrates and lectins]
Neoplasms
A fluorometric assay for glycosyltransferase activities using sugars aminated and tagged with 7-hydroxycoumarin-3-carboxylic acid as substrates and high performance liquid chromatography.
A genetic strategy involving a glycosyltransferase promoter and a lipid translocating enzyme to eliminate cancer cells.
A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis.
A High-Throughput Glycosyltransferase Inhibition Assay for Identifying Molecules Targeting Fucosylation in Cancer Cell-Surface Modification.
A recombinant fungal lectin for labeling truncated glycans on human cancer cells.
A secreted type of beta 1,6-N-acetylglucosaminyltransferase V (GnT-V) induces tumor angiogenesis without mediation of glycosylation: a novel function of GnT-V distinct from the original glycosyltransferase activity.
A secreted type of beta1,6 N-acetylglucosaminyltransferase V (GnT-V), a novel angiogenesis inducer, is regulated by gamma-secretase.
A simple and specific assay of glycosyltransferase and glycosidase activities by an enzyme-linked immunosorbent assay method, and its application to assay of galactosyltransferase activity in sera from patients with cancer.
A Systematic Review on the Implications of O-linked Glycan Branching and Truncating Enzymes on Cancer Progression and Metastasis.
A tumorigenic cell line derived from a hamster cholangiocarcinoma associated with Opisthorchis felineus liver fluke infection.
Aberrant Glycosylation in Cancer: A Novel Molecular Mechanism Controlling Metastasis.
Aberrant Glycosylation Promotes Lung Cancer Metastasis through Adhesion to Galectins in the Metastatic Niche.
ABH blood group antigen expression, synthesis, and degradation in human colonic adenocarcinoma cell lines.
ABO blood-group antigens in oral cancer.
Alterations of cell surface carbohydrates and inhibition of metastatic property of murine melanomas by alpha 1,3 galactosyltransferase gene transfection.
An optimised assay for quantitative, high-throughput analysis of polysialyltransferase activity.
Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
Biological and Clinicopathological Implications of Beta-3-N-acetylglucosaminyltransferase 8 in Triple-negative Breast Cancer.
Biosignals modulated by tumor-associated carbohydrate antigens: novel targets for cancer therapy.
Biosynthetic basis of incompatible histo-blood group A antigen expression: anti-A transferase antibodies reactive with gastric cancer tissue of type O individuals.
BORIS Expression in Ovarian Cancer Precursor Cells Alters the CTCF Cistrome and Enhances Invasiveness through GALNT14.
C1GALT1 in health and disease.
Cancer-associated changes in glycosylation of fibronectin. Immunohistological localization of oncofetal fibronectin defined by monoclonal antibodies.
Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer.
Clinical significance of LARGE1 in progression of liver cancer and the underlying mechanism.
Critical roles of mucin 1 glycosylation by transactivated polypeptide N-acetylgalactosaminyltransferase 6 in mammary carcinogenesis.
Current relevance of incomplete synthesis and neo-synthesis for cancer-associated alteration of carbohydrate determinants-Hakomori's concepts revisited.
Development and Validation of a Universal High-Throughput UDP-Glycosyltransferase Assay with a Time-Resolved FRET Signal.
Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer.
Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets.
Effects of carbocisteine on sialyl-Lewis x expression in an airway carcinoma cell line stimulated with tumor necrosis factor-alpha.
Expression analysis of 0-series gangliosides in human cancer cell lines with monoclonal antibodies generated using knockout mice of ganglioside synthase genes.
Familial Solitary Chondrosarcoma Resulting from Germline EXT2 Mutation.
Fucosyltransferase 8 regulation and breast cancer suppression by transcription factor activator protein 2?.
FUT4 is involved in PD-1-related immunosuppression and leads to worse survival in patients with operable lung adenocarcinoma.
FUT7 Promotes the Epithelial-Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma.
Genomics and proteomics of bone cancer.
Glycan Node Analysis: A Bottom-up Approach to Glycomics.
Glycoproteins in the Sera of Oncological Patients.
Glycosylation markers in cancer.
Glycosyltransferase activities of Ehrlich ascites tumor cells: detection, isolation, and characterization using oligosaccharide-Synsorb beads.
Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes.
Glycosyltransferase levels in familial polyposis coli.
Glycosyltransferase levels in tumors metastatic to liver and in uninvolved liver tissue.
Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy.
GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ER? glycosylation and stability to cancer.
High expression of ?3GnT8 is associated with the metastatic potential of human glioma.
Immunohistochemical study of type-1 blood antigen expressions in thyroid tumors: the significance for papillary carcinomas.
Impact of sialyltransferase ST6GAL1 overexpression on different colon cancer cell types.
Increased expression of the enzyme beta 1-4-galactosyltransferase is associated with human parotid neoplasms.
Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9.
Mucin oligosaccharide biosynthesis in human colonic cancerous tissues and cell lines.
Mutation spectrum of EXT1 and EXT2 in the Saudi patients with hereditary multiple exostoses.
New monoallelic (partial tandem duplication) mutation of HNF1a gene in steatotic hepatocellular adenoma.
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.
Overexpression of ?2,3sialyl T-antigen in breast cancer determined by miniaturized glycosyltransferase assays and confirmed using tissue microarray immunohistochemical analysis.
Overexpression of sialyltransferase CMP-sialic acid:Galbeta1,3GalNAc-R alpha6-Sialyltransferase is related to poor patient survival in human colorectal carcinomas.
Pancreas carcinoma antigen fused to invariant chain elicits T-cell response and tumor growth inhibition.
Physiological roles of N-acetylglucosaminyltransferase V(GnT-V) in mice.
POFUT1 mRNA expression as an independent prognostic parameter in muscle-invasive bladder cancer.
Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer.
Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of alpha1,2-fucosyltransferase activities.
Recent advances in developing synthetic carbohydrate-based vaccines for cancer immunotherapies.
Remodeling of glycoconjugates on CD44 enhances cell adhesion to hyaluronate, tumor growth and metastasis in B16 melanoma cells expressing beta1,4-N-acetylglucosaminyltransferase III.
Sialylation of beta1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis.
Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.
Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells.
ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function.
Synthesis of ABH blood group substances in bladder tumours.
Synthesis of O-glycan core 3: characterization of UDP-GlcNAc: GalNAc-R beta 3-N-acetyl-glucosaminyltransferase activity from colonic mucosal tissues and lack of the activity in human cancer cell lines.
Synthetic self-adjuvanting glycopeptide cancer vaccines.
The effect of plant lectins on the survival and malignant behaviors of thyroid cancer cells.
The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability.
The glycosyltransferase LARGE2 is repressed by Snail and ZEB1 in prostate cancer.
The glycosyltransferase ST6Gal-I is enriched in cancer stem-like cells in colorectal carcinoma and contributes to their chemo-resistance.
The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential.
The pattern of glycosyl- and sulfotransferase activities in cancer cell lines: a predictor of individual cancer-associated distinct carbohydrate structures for the structural identification of signature glycans.
The structural relationship of blood group-related oligosaccharides in human carcinoma to biological function: a perspective.
The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype.
Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer.
Thomsen-friedenreich disaccharide immunogenicity.
Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms.
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.
Tumor-associated blood group antigen expressions and immunoglobulins associated with tumors.
Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation.
Upregulation of N-acetylglucosaminyltransferase-V by heparin-binding EGF-like growth factor induces keratinocyte proliferation and epidermal hyperplasia.
Upregulation of OGT by Caveolin-1 promotes hepatocellular carcinoma cell migration and invasion.
[Carbohydrate antigens as cell adhesion molecules]
[Effects of Compound Aconitum Polysaccharide on Glycosylation of Tumor Cells].
[Glycosyltransferase genes as tumor marker]
[Molecular mechanism of antisense glycosyltransferase oligonucleotide inhibiting human gliomas cell line SWO-38]
[Tumor metastases and adhesion molecules carbohydrates and lectins]
Neoplastic Cells, Circulating
Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy.
Nervous System Malformations
Aberrant development of neuromuscular junctions in glycosylation-defective Large(myd) mice.
Neuroblastoma
Ganglioside GM2/GD2 synthetase mRNA is a marker for detection of infrequent neuroblastoma cells in bone marrow.
Glycosylation pathways in the biosynthesis of gangliosides in melanoma and neuroblastoma cells: relative glycosyltransferase levels determine ganglioside patterns.
Relationship of glycosyltransferases and mRNA levels to ganglioside expression in neuroblastoma and melanoma cells.
Neurodegenerative Diseases
Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration.
Neuroinflammatory Diseases
The glycosyltransferase EXTL2 promotes proteoglycan deposition and injurious neuroinflammation following demyelination.
Non-alcoholic Fatty Liver Disease
ABO blood group and risk of newly diagnosed nonalcoholic fatty liver disease: A case-control study in Han Chinese population.
Obesity
The rs4285184 polymorphism of the MGAT1 gene as a risk factor for obesity in the Mexican population.
Osteochondroma
Detection of exostosin glycosyltransferase gene mutations in patients with non-hereditary osteochondromas of the mandibular condyle.
Osteosarcoma
Primary human osteoblasts and bone cancer cells as models to study glycodynamics in bone.
Otitis Media
Identification of new genetic regions more prevalent in nontypeable Haemophilus influenzae otitis media strains than in throat strains.
Identification of the lipooligosaccharide biosynthesis gene lic2B as a putative virulence factor in strains of nontypeable Haemophilus influenzae that cause otitis media.
Ovarian Neoplasms
Glycosyltransferase and glycosidase activities in ovarian cancer patients.
MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway.
Overexpression of glycosyltransferase 8 domain containing 2 confers ovarian cancer to CDDP resistance by activating FGFR/PI3K signalling axis.
Sox2 promotes expression of the ST6Gal-I glycosyltransferase in ovarian cancer cells.
The glycosyltransferase GnT-III activates Notch signaling and drives stem cell expansion to promote the growth and invasion of ovarian cancer.
The role of glycosyltransferase enzyme GCNT3 in colon and ovarian cancer prognosis and chemoresistance.
Pancreatic Neoplasms
ABO blood groups and pancreatic cancer risk and survival: Results from the PANcreatic Disease ReseArch (PANDoRA) consortium.
Clinical utility of quantitative RT-PCR targeted to alpha1,4-N-acetylglucosaminyltransferase mRNA for detection of pancreatic cancer.
Expression of microRNA-15b and the glycosyltransferase GCNT3 correlates with antitumor efficacy of Rosemary diterpenes in colon and pancreatic cancer.
Expression of Tn, sialosyl Tn, and T antigens in human pancreas.
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.
The role of the histoblood ABO group in cancer.
Variant ABO Blood Group Alleles, Secretor Status and Risk of Pancreatic Cancer: Results from the Pancreatic Cancer Cohort Consortium.
Peptic Ulcer
Clinical relevance and diversity of two homologous genes encoding glycosyltransferases in Helicobacter pylori.
Helicobacter pylori in pediatrics.
Periodontitis
Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies.
Pheochromocytoma
Effect of nerve growth factor and forskolin on glycosyltransferase activities and expression of a globo-series glycosphingolipid in PC12D pheochromocytoma cells.
Porcine Reproductive and Respiratory Syndrome
The glycosyltransferase ST3GAL2 modulates virus proliferation and the inflammation response in porcine reproductive and respiratory syndrome virus infection.
Prostatic Neoplasms
A common regulatory variant in SLC35B4 influences the recurrence and survival of prostate cancer.
Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin.
Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9.
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1.
Overexpression of ? (1,6) fucosyltransferase associated with aggressive prostate cancer.
The glycosyltransferase LARGE2 is repressed by Snail and ZEB1 in prostate cancer.
TNF? enhances the motility and invasiveness of prostatic cancer cells by stimulating the expression of selective glycosyl- and sulfotransferase genes involved in the synthesis of selectin ligands.
protein o-mannose beta-1,4-n-acetylglucosaminyltransferase deficiency
Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion.
Pulmonary Disease, Chronic Obstructive
Keratan sulfate-based glycomimetics using Langerin as a target for COPD: lessons from studies on Fut8 and core fucose.
Purpura
A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase.
Renal Insufficiency
Protein glycosylation: chaperone mutation in Tn syndrome.
Retinitis Pigmentosa
Glycosyltransferase activities in lymphocytes of patients with retinitis pigmentosa.
Rhabdomyosarcoma
Exogenous expression of the glycosyltransferase LARGE1 restores ?-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma.
Sarcoma
Transformation of Swiss 3T3 cells by murine sarcoma virus is followed by decrease in a glycolipid glycosyltransferase.
Spastic Paraplegia, Hereditary
Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia.
Starvation
Regulation of waaH by PhoB during Pi Starvation Promotes Biofilm Formation by Escherichia coli O157:H7.
Stomach Neoplasms
Bioinformatics insight into glycosyltransferase gene expression in gastric cancer: POFUT1 is a potential biomarker.
Diagnostic utility of glycosyltransferase mRNA expression in gastric cancer.
Therapeutic adenoviral gene transfer of a glycosyltransferase for prevention of peritoneal dissemination and metastasis of gastric cancer.
Superinfection
Thousands of previously unknown phages discovered in whole-community human gut metagenomes.
Teratocarcinoma
Branching beta 1-6N-acetylglucosaminetransferases and polylactosamine expression in mouse F9 teratocarcinoma cells and differentiated counterparts.
Tuberculosis
AftD, a novel essential arabinofuranosyltransferase from mycobacteria.
Biochemical characterization of the retaining glycosyltransferase glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis.
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.
Biosynthesis of mycobacterial lipoarabinomannan: role of a branching mannosyltransferase.
Biosynthetic origin of the galactosamine substituent of arabinogalactan in mycobacterium tuberculosis.
Characterization of mycobacterial protein glycosyltransferase activity using synthetic peptide acceptors in a cell-free assay.
Deciphering the genetic bases of the structural diversity of phenolic glycolipids in strains of the Mycobacterium tuberculosis complex.
Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils.
Dissecting the Structural and Chemical Determinants of the "Open-to-Closed" Motion in the Mannosyltransferase PimA from Mycobacteria.
Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis.
Genetic basis for the synthesis of the immunomodulatory mannose caps of lipoarabinomannan in Mycobacterium tuberculosis.
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall.
Identification of a polyprenylphosphomannosyl synthase involved in the synthesis of mycobacterial mannosides.
In vitro and in vivo characterization of a Mycobacterium tuberculosis mutant deficient in glycosyltransferase Rv1500.
Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics.
Monitoring processivity and length control of a carbohydrate polymerase.
Ppm1-encoded polyprenyl monophosphomannose synthase activity is essential for lipoglycan synthesis and survival in mycobacteria.
The mshA gene encoding the glycosyltransferase of mycothiol biosynthesis is essential in Mycobacterium tuberculosis Erdman.
Urinary Bladder Neoplasms
Blood group ABO and Lewis antigens in bladder tumors: correlation between glycosyltransferase activity and antigen expression.
The blood group ABO gene transcript is down-regulated in human bladder tumors and growth-stimulated urothelial cell lines.
Vaccinia
The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose.
Vesicular Stomatitis
Glycosylation of VSV glycoprotein is similar in cystic fibrosis, heterozygous carrier, and normal human fibroblasts.
Virus Diseases
The glycosyltransferase ST3GAL2 modulates virus proliferation and the inflammation response in porcine reproductive and respiratory syndrome virus infection.
Tomato glycosyltransferase Twi1 plays a role in flavonoid glycosylation and defence against virus.
von Willebrand Diseases
Long-term balancing selection at the blood group-related gene B4galnt2 in the genus Mus (Rodentia; Muridae).
Walker-Warburg Syndrome
Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT).
Biochemical correlation of activity of the alpha-dystroglycan-modifying glycosyltransferase POMGnT1 with mutations in Muscle-Eye-Brain disease.
Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of ?-dystroglycan.
Wiskott-Aldrich Syndrome
Expression of human Wiskott-Aldrich syndrome protein in patients' cells leads to partial correction of a phenotypic abnormality of cell surface glycoproteins.