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Information on EC 2.4.1.46 - monogalactosyldiacylglycerol synthase
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2.4.1.46 monogalactosyldiacylglycerol synthaseIUBMB Comments
This enzyme adds only one galactosyl group to the diacylglycerol; EC 2.4.1.241, digalactosyldiacylglycerol synthase, adds a galactosyl group to the product of the above reaction. There are three isoforms in Arabidopsis that can be divided into two types, A-type (MGD1) and B-type (MGD2 and MGD3). MGD1 is the isoform responsible for the bulk of monogalactosyldiacylglycerol (MGDG) synthesis in Arabidopsis .
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Word Map
- 2.4.1.46
- chloroplast
- galactolipids
- digalactosyldiacylglycerol
-
thylakoid
-
plastid
- phosphatidylglycerol
- glycerolipids
-
type-b
-
extraplastidial
- sulfoquinovosyldiacylglycerols
-
monotopic
- monoglucosyldiacylglycerol
- protochlorophyllide
-
de-epoxidase
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Synonyms
mgdg synthase, monogalactosyldiacylglycerol synthase, sll1377, atmgd1, monogalactosyldiacylglycerol synthase1, monogalactosyldiacylglycerol synthase 1, mgdg synthase 1, atmgd2, atmgd3, 1,2-diacylglycerol 3-beta-galactosyltransferase, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
1,2-diacylglycerol 3-beta-galactosyltransferase
-
-
-
-
galactosyltransferase, uridine diphosphogalactose-1,2-diacylglycerol
-
-
-
-
MGD
MGD1
MGD2
MGD3
MgdA
MGDG synthase
monogalactosyldiacylglycerol synthase
type A monogalactosyldiacylglycerol synthase
type B monogalactosyldiacylglycerol synthase
UDP galactose-1,2-diacylglycerol galactosyltransferase
-
-
-
-
UDP-galactose-diacylglyceride galactosyltransferase
-
-
-
-
UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase
UDP-galactose:diacylglycerol galactosyltransferase
-
-
-
-
uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase
-
-
-
-
MGDG synthase
-
-
-
-
UDP-galactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-galactose + a 1,2-diacyl-sn-glycerol = UDP + a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
-
-
-
-
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SYSTEMATIC NAME
IUBMB Comments
UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase
This enzyme adds only one galactosyl group to the diacylglycerol; EC 2.4.1.241, digalactosyldiacylglycerol synthase, adds a galactosyl group to the product of the above reaction. There are three isoforms in Arabidopsis that can be divided into two types, A-type (MGD1) and B-type (MGD2 and MGD3). MGD1 is the isoform responsible for the bulk of monogalactosyldiacylglycerol (MGDG) synthesis in Arabidopsis [4].
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CAS REGISTRY NUMBER
COMMENTARY
37277-55-7
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
UDP-alpha-D-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
-
-
-
?
UDP-galactose + 1,2-dicaproylglycerol
UDP + 3-beta-D-galactosyl-1,2-dicaproylglycerol
-
-
-
?
UDP-galactose + 1,2-didecanoylglycerol
UDP + 3-beta-D-galactosyl-1,2-didecanoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilauroylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilauroylglycerol
-
-
-
?
UDP-galactose + 1,2-myristoylglycerol
UDP + 3-beta-D-galactosyl-1,2-myristoylglycerol
-
-
-
?
UDP-galactose + sn-1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoyl-sn-glycerol
-
-
-
?
UDP-galactose + sn-1-oleoyl-sn-2-palmitoyl-glycerol
UDP + 3-beta-D-galactosyl-sn-1-oleoyl-sn-2-palmitoyl-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
ir
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
MGD activity is reversibly regulated by reduction and oxidation in vitro
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
requires the 1,2-isomer of the diglyceride substrate and prefers diglycerides with long-chain-saturated fatty acid constituents
i.e. 1,2-di-O-acyl-(beta-D-galactopyranosyl)-sn-glycerol
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
-
?
UDP-galactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
preferred substrate
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dilinoleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dilinoleoylglycerol
-
best substrate
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
-
?
UDP-galactose + 1,2-dioleoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dioleoylglycerol
-
-
-
?
UDP-galactose + 1,2-dipalmitoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dipalmitoylglycerol
-
-
-
?
UDP-galactose + 1,2-dipalmitoylglycerol
UDP + 3-beta-D-galactosyl-1,2-dipalmitoylglycerol
-
-
-
?
UDP-galactose + 1,2-distearoylglycerol
UDP + 3-beta-D-galactosyl-1,2-distearoylglycerol
-
-
-
?
UDP-galactose + 1,2-distearoylglycerol
UDP + 3-beta-D-galactosyl-1,2-distearoylglycerol
-
-
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
enzyme is responsible for the biosynthesis of monogalactosyl diglyceride in brain and may function significantly in myelination
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
involved in biosynthesis of monogalactosyldiacylglycerol
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
additional information
?
-
-
MGDG synthase catalyzes the final step in thylakoid membrane lipid monogalactosyldiacylglycerol, MGDG, biosynthesis in the plastid envelope
-
-
?
additional information
?
-
-
mono- and digalactosyldiacylglycerol constitute the bulk of membrane lipids in plant chloroplasts and are essential for chloroplast biogenesis and photoautotrophic growth. Type B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling and are crucial for low-phosphate adaptation, overview
-
-
?
additional information
?
-
-
regulation of MGDGsynthesis by phosphatidic acid, which is a general precursor in the synthesis of all glycerolipids and is also a signaling molecule in plants
-
-
?
additional information
?
-
-
binding site for UDP-Gal lays in the cleft separating the two Rossmann folds involving residues of a conserved UDP-sugar binding pocket in the C-domain
-
-
?
additional information
?
-
reaction is proposed to to occur in a single displacement SN2 mechanism, with formation of an oxocarbenium ion transition state assisted by a catalytic base, H155. Phosphatidylglycerol binds to the active site where it is stabilized by interactions involving residues P189 and H155, creating an acid-base charge-relay system
-
-
-
additional information
?
-
-
in etiolated seedlings white light induces a transient increase in MGD mRNA, followed by a subsequent increase in enzyme activity. When cotyledons were detached from seedlings, these light-induced changes diminished
-
-
?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
ir
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
?
UDP-alpha-D-galactose + 1,2-diacyl-sn-glycerol
UDP + 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol
-
-
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
type B MGDG synthases may have roles during pollen germination and pollen tube growth and may be acting primarily to supply MGDG as a precursor for DGDG synthesis. Expression of atMGD2 and atMGD3, but not atMGD1, is strongly induced during phosphate starvation, particularly in roots
-
-
?
UDP-galactose + 1,2-diacyl-sn-glycerol
UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol
-
MGD activity is reversibly regulated by reduction and oxidation in vitro
-
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
enzyme is responsible for the biosynthesis of monogalactosyl diglyceride in brain and may function significantly in myelination
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
involved in biosynthesis of monogalactosyldiacylglycerol
-
?
UDPgalactose + 1,2-diacylglycerol
UDP + 3-beta-D-galactosyl-1,2-diacylglycerol
-
last step in monogalactosyldiacylglycerol biosynthesis
-
?
additional information
?
-
-
MGDG synthase catalyzes the final step in thylakoid membrane lipid monogalactosyldiacylglycerol, MGDG, biosynthesis in the plastid envelope
-
-
?
additional information
?
-
-
mono- and digalactosyldiacylglycerol constitute the bulk of membrane lipids in plant chloroplasts and are essential for chloroplast biogenesis and photoautotrophic growth. Type B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling and are crucial for low-phosphate adaptation, overview
-
-
?
additional information
?
-
-
regulation of MGDGsynthesis by phosphatidic acid, which is a general precursor in the synthesis of all glycerolipids and is also a signaling molecule in plants
-
-
?
additional information
?
-
-
in etiolated seedlings white light induces a transient increase in MGD mRNA, followed by a subsequent increase in enzyme activity. When cotyledons were detached from seedlings, these light-induced changes diminished
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Ca2+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
Co2+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
Fe2+
-
addition of cation stimulates, order of efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
K+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
Mg2+
Mn2+
Na+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
Ni2+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
Mg2+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+ , Na+
Mn2+
-
addition of cation stimulates, efficiency in descending order: Mn2+, Co2+, Mg2+, Fe2+, Ca2+, Ni2+, K+, Na+
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
citraconic anhydride
-
0.01 and 0.05 mM, 47% and 97% inactivation after 30 min, respectively
o-phenanthroline
-
0.1 mM, 55% inhibition, 1,2-dioleoylglycerol protects and activates enzyme
tert-butyoxycarbonyl-L-methionine hydrosuccinimidyl ester
-
0.2 mM, almost complete inactivation after 30 min
N-ethylmaleimide
-
0.005-0.1 mM, complete inhibition of solubilized enzyme; 0.5 mM, 57% inhibition
N-ethylmaleimide
-
5 mM, complete inactivation of enzyme in envelope membranes, 0.008 mM, complete inactivation of solubilized enzyme, preincubation with 1,2-dioleoylglycerol protects
N-ethylmaleimide
0.15 mM, 65% inactivation after 10 min, recombinant isoenzyme MGD A, preincubation with diacylglycerol and/or phosphatidylglycerol protects
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
illumination
-
3fold increase of activity in dark-grown seedlings 42 h after illumination
-
Lipid
-
addition of lipids extracted from chloroplast membranes is necessary to reveal activity of highly delipidated enzyme fraction
phosphatidylethanolamine
-
mild activity-enhancing effect (60%, at 40 mol percent concentration)
phosphatidylglycerol
-
best activator of partially purified, delipidated enzyme
phosphatidylinositol
-
activation of partially purified, delipidated enzyme
sulfoquinovosyldiacylglycerol
-
most potent activator (100% increase of activity at 10 mol percent concentration)
phosphatidic acid
-
allosterically activates MGD1, half-maximal activation at about 0.2 mol%. With 0.15 mol% of phosphatidic acid, the enzyme velocity versus substrate curve is sigmoid, whereas with 1.5 mol% of phosphatidic acid, the curve is hyperbolic. MGDG synthase activity of leaf homogenates is dependent on the constant presence of phosphatidic acid, decrease of phosphatidic acid production leads to a decrease of the MGDG synthase activity. Molecular discrimination of phosphatidic acid and phosphatidylglycerol binding sites, overview
additional information
-
intramolecular disulfide bonds are involved in MGD activation
-
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Starvation
An engineered lipid remodeling system using a galactolipid synthase promoter during phosphate starvation enhances oil accumulation in plants.
Starvation
Arabidopsis type B monogalactosyldiacylglycerol synthase genes are expressed during pollen tube growth and induced by phosphate starvation.
Starvation
Type-B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling, and are crucial for low-phosphate adaptation.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.02
dioleoylglycerol
-
in envelope membrane vesicles, at 0.25 mg/ml protein
additional information
additional information
-
Km value for 1,2-dioleyolglycerol and 1,2-dilinoleoylglycerol in mixed micelles and envelope membrane vesicles expressed as mol fractions
-
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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
0.01
galvestine-1
Arabidopsis thaliana
-
pH 7.8, temperature not specified in the publication
0.012
galvestine-2
Arabidopsis thaliana
-
pH 7.8, temperature not specified in the publication
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
0.0531
purified His tagged protein, not significantly influenced by phosphatidic acid, pH 7.8, 30°C
7.04
membrane fraction of mgdA expressing Escherichia coli, not significantly influenced by phosphatidic acid, pH 7.8, 30°C
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
5.5 - 9
-
55% of maximal activity at pH 5.5, 85% of maximal activity at pH 9.0
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
