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Information on EC 2.4.1.387 - isomaltosyltransferase

for references in articles please use BRENDA:EC2.4.1.387

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IUBMB Comments

The enzyme, found in bacteria that produce cyclobis-(1→6)-α-nigerosyl, acts on the products of EC 2.4.1.24, 1,4-α-glucan 6-α;-glucosyltransferase. It catalyses the α-(1→3) transfer of the isomaltosyl moiety of one substrate to another, resulting in α-isomaltosyl-(1→3)-α-isomaltosyl-α-(1→4)-glucan formation. In addition, the enzyme catalyses the intramolecular cyclization of the product, eventually generating cyclobis-(1→6)-α-nigerosyl.

The expected taxonomic range for this enzyme is: Sporosarcina globispora

Synonyms
alternanase, 3-alpha-isomaltosyltransferase, isomaltosyltransferase, isomaltosyl transferase, cycloalternan-forming enzyme, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 alpha-isomaltosyl-(1->4)-maltotriose = alpha-isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose + maltotriose
show the reaction diagram
(1)
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alpha-isomaltosyl-(1->3)-alpha-isomaltosyl-(1->4)-maltotriose = cyclobis-(1->6)-alpha-nigerosyl + maltotriose
show the reaction diagram
(2)
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PATHWAY SOURCE
PATHWAYS
MetaCyc
cyclobis-(1rarr6)-alpha-nigerosyl biosynthesis
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