Information on EC 2.4.1.382 - CDP-abequose:alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und alpha-1,3-abequosyltransferase
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The enzyme, present in Salmonella strains that belong to group C2, participates in the biosynthesis of the repeat unit of O antigens produced by these strains.
The expected taxonomic range for this enzyme is: Salmonella enterica
The enzyme, present in Salmonella strains that belong to group C2, participates in the biosynthesis of the repeat unit of O antigens produced by these strains.
Substrates: abequosyltransferase RfbR of group C2 can transfer abequose onto the intermediates 2-O-acetyl-Rha-Man-Man-Gal-PP-decaprenol and Rha-Man-Man-Gal-PP-decaprenol, but the efficiency of transfer to the second intermediate is much lower Products: -
Substrates: abequosyltransferase RfbR of group C2 can transfer abequose onto the intermediates 2-O-acetyl-Rha-Man-Man-Gal-PP-decaprenol and Rha-Man-Man-Gal-PP-decaprenol, but the efficiency of transfer to the second intermediate is much lower Products: -
construction of bivalent vaccines for preventing both Salmonella typhimurium and Salmonella newport infections by using the aspartate semialdehyde dehydrogenase-based balanced-lethal vector-host system. The constructed plasmid pCZ11 carrying a subset of the Salmonella newport O-antigen gene cluster including the wzx-wbaR-wbaL-wbaQ-wzy-wbaW-wbaZ genes is introduced into Salmonella typhimurium. Upon deletion of the crp gene for attenuation purposes, BALB/c mice are orally immunized with the strains. Compared with a mock immunization, immunization with the vaccine strains induces significant serum IgG responses against both Salmonella typhimurium and Salmonella newport lipopolysaccharide