Information on EC 2.4.1.363 - ginsenoside 20-O-glucosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.363 ginsenoside 20-O-glucosyltransferase
IUBMB Comments
The enzyme, characterized from the plant Panax ginseng, transfers a glucosyl moiety to the free C20(S)-OH group of dammarane derivative substrates, including protopanaxatriol, dammarenediol II, (20S)-ginsenoside Rh2, and (20S)-ginsenoside Rg3. It does not act on the 20R epimer of protopanaxadiol, or on ginsenosides that are glucosylated at the C-6 position, such as ginsenoside Rh1 or ginsenoside Rg2.
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The expected taxonomic range for this enzyme is: Panax ginseng
Synonyms
UGT, UGT71A27, UGTPg1, UGTPg102, UGTPg103, uridine diphosphate glycosyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucose + (20S)-protopanaxadiol = UDP + ginsenoside C-K
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PATHWAY SOURCE
PATHWAYS
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