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Information on EC 2.4.1.361 - GDP-mannose:di-myo-inositol-1,3'-phosphate beta-1,2-mannosyltransferase

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IUBMB Comments
The enzyme from the hyperthermophilic bacterium Thermotoga maritima is involved in the synthesis of the solutes 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate and 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate.
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The enzyme appears in viruses and cellular organisms
Synonyms
mdip synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 GDP-alpha-D-mannose + bis(myo-inositol) 1,3'-phosphate = 2 GDP + 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
show the reaction diagram
overall reaction
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GDP-alpha-D-mannose + 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate = GDP + 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
show the reaction diagram
(1b)
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GDP-alpha-D-mannose + bis(myo-inositol) 1,3'-phosphate = GDP + 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate
show the reaction diagram
(1a)
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