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Information on EC 2.4.1.35 - phenol beta-glucosyltransferase
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EC Tree
2.4.1.35 phenol beta-glucosyltransferaseIUBMB Comments
Acts on a wide range of phenols.
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Word Map
- 2.4.1.35
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ecdysteroid
- nucleopolyhedrovirus
-
autographa
- udp-glycosyltransferase
- steviol
- granulovirus
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rebaudioside
-
multicapsid
- analysis
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
udp-glucosyltransferase, udp-glucose glucosyltransferase, udp glucosyltransferase, udp-glucose:glucosyltransferase, ugt84a22, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
glucosyltransferase, uridine diphospho-
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phenol-beta-D-glucosyltransferase
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UDP glucosyltransferase
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UDP-glucose glucosyltransferase
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UDP-glucosyltransferase
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uridine diphosphoglucosyltransferase
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
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SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:phenol beta-D-glucosyltransferase
Acts on a wide range of phenols.
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CAS REGISTRY NUMBER
COMMENTARY
9046-69-9
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-glucose + 3-hydroxyflavone
UDP + 3-[(beta-D-glucopyranosyl)oxy]-flavone
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-
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?
UDP-alpha-D-glucose + quercetin
UDP + quercetin 3'-O-beta-D-glucoside + quercetin 7-O-beta-D-glucoside + quercetin 7,3'-di-O-beta-D-glucoside
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?
UDP-galactose + sinapic acid
UDP + sinapoyl 3-O-beta-D-galactoside
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?
UDP-glucose + 3-hydroxycoumarine
UDP + 3-hydroxycoumaryl beta-D-glucoside
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?
UDP-glucose + 4-hydroxybenzoic acid
UDP + 4-hydroxybenzoyl 3-O-beta-D-glucoside
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?
UDP-glucose + 4-hydroxyphenylethanol
UDP + 4-hydroxyphenylethyl beta-D-glucoside
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?
UDP-glucose + benzoic acid
UDP + benzoyl 3-O-beta-D-glucoside
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?
UDP-glucose + cinnamic acid
UDP + cinnamoyl beta-D-glucoside
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?
UDP-glucose + ferulic acid
UDP + feruloyl beta-D-glucoside
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?
UDP-glucose + formononetin
UDP + formononetin 7-O-beta-D-glucoside
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?
UDP-glucose + isoferulic acid
UDP + isoferuloyl beta-D-glucoside
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?
UDP-glucose + luteolin
UDP + luteolin 3'-O-beta-D-glucoside + luteolin 7-O-beta-D-glucoside + luteolin 7,3'-di-O-beta-D-glucoside
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?
UDP-glucose + m-coumaric acid
UDP + m-coumaroyl beta-D-glucoside
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?
UDP-glucose + o-coumaric acid
UDP + o-coumaroyl beta-D-glucoside
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?
UDP-glucose + p-coumaric acid
UDP + p-coumaroyl 3-O-beta-D-glucoside
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?
UDP-glucose + syringic acid
UDP + syringoyl 3-O-beta-D-glucoside
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?
UDP-xylose + 4-methylumbelliferone
UDP + 4-methylumbelliferyl beta-D-xyloside
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?
UDPglucose + 4'-hydroxyflavone
UDP + 4'-hydroxyflavone 4'-beta-D-glucoside
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?
UDPglucose + 4-hydroxybenzoic acid methyl ester
UDP + 4-beta-D-glucopyranosyloxy-benzoic acid methyl ester
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?
UDPglucose + 4-methylumbelliferone
UDP + 4-methylumbelliferyl beta-D-glucoside
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?
UDPglucose + 5-hydroxyflavone
UDP + 5-hydroxyflavone 5-beta-D-glucoside
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?
UDPglucose + 6-hydroxyflavone
UDP + 6-hydroxyflavone 6-beta-D-glucoside
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?
UDPglucose + 7-hydroxyflavone
UDP + 7-hydroxyflavone 7-beta-D-glucoside
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?
UDPglucose + beta-thujaplicin
UDP + beta-thujaplicin beta-D-monoglucoside
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TDPglucose also acts as a glucose donor, but not ADPglucose, GDPglucose and CDPglucose
both products: 4-isopropyltropolone 2-O-beta-D-glucopyranoside and 6-isopropyltropolone 2-O-beta-D-glucopyranoside
?
UDPglucose + ferulic acid
UDP + 4-O-beta-D-glucopyranosyl-3-methoxycinnamic acid
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?
UDPglucose + o-hydroxy-trans-cinnamic acid
UDP + 2-beta-D-glucopyranosyloxy-trans-cinnamic acid
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?
UDPglucose + p-aminobenzoic acid
?
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TDPglucose also acts as a glucose donor, but not ADPglucose, GDPglucose and CDPglucose
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?
UDPglucose + p-coumaric acid
UDP + 4-beta-D-glucopyranosyloxy-trans-cinnamic aicd
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?
UDPglucose + p-hydroxybiphenyl
UDP + p-hydroxybiphenyl beta-D-glucoside
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?
UDPglucose + p-hydroxycinnamic acid
UDP + 4-beta-D-glucopyranosyloxy-trans-cinnamic acid
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?
UDPglucose + salicylic acid
UDP + 2-(beta-D-glucopyranosyloxy)benzoate
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?
ADP-glucose + p-nitrophenol
ADP + p-nitrophenyl beta-D-glucoside
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?
ADP-glucose + p-nitrophenol
ADP + p-nitrophenyl beta-D-glucoside
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?
ADP-glucose + p-nitrophenol
ADP + p-nitrophenyl beta-D-glucoside
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?
CDP-glucose + p-nitrophenol
CDP + p-nitrophenyl beta-D-glucoside
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?
CDP-glucose + p-nitrophenol
CDP + p-nitrophenyl beta-D-glucoside
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?
CDP-glucose + p-nitrophenol
CDP + p-nitrophenyl beta-D-glucoside
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?
dTDP-glucose + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucoside
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?
dTDP-glucose + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucoside
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?
dTDP-glucose + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucoside
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?
dTDP-glucose + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucoside
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?
GDP-glucose + p-nitrophenol
GDP + p-nitrophenyl beta-D-glucoside
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?
GDP-glucose + p-nitrophenol
GDP + p-nitrophenyl beta-D-glucoside
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?
GDP-glucose + p-nitrophenol
GDP + p-nitrophenyl beta-D-glucoside
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?
UDP-glucose + caffeic acid
UDP + caffeoyl 3-O-beta-D-glucoside
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specific for the 3-hydroxyl, and not the 4-hydroxyl, position of caffeic acid.
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?
UDP-glucose + caffeic acid
UDP + caffeoyl 3-O-beta-D-glucoside
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?
UDPglucose + 2-aminophenol
UDP + 2-aminophenyl beta-D-glucoside
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specific for UDPglucose, not replaceable by ADPglucose, CDPglucose, or TDPglucose
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?
UDPglucose + 2-aminophenol
UDP + 2-aminophenyl beta-D-glucoside
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specific for UDPglucose, not replaceable by ADPglucose, CDPglucose, or TDPglucose
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + 4-hydroxycoumarine
UDP + 4-hydroxycoumaryl beta-D-glucoside
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?
UDPglucose + catechol
UDP + 2-(beta-D-glucopyranosyloxy)phenol
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?
UDPglucose + guaiacol
UDP + 2-methoxyphenyl beta-D-glucoside
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?
UDPglucose + hydroquinone
UDP + 4-beta-D-glucopyranosyloxyphenol
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?
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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tetrasaccharide repeats: Glc-Glc-Gal-Man
?
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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lipophosphoglycan from Sudanes L. donovani which is not glycosylated
tetrasaccharide repeats: Glc-Glc-Gal-Man
?
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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tetrasaccharide repeats: Glc-Glc-Gal-Man
?
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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lipophosphoglycan from Sudanes L. donovani which is not glycosylated
tetrasaccharide repeats: Glc-Glc-Gal-Man
?
UDPglucose + p-methoxyphenol
UDP + p-methoxyphenyl beta-D-glucoside
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?
UDPglucose + p-nitrophenol
UDP + p-nitrophenyl beta-D-glucoside
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?
UDPglucose + p-nitrophenol
UDP + p-nitrophenyl beta-D-glucoside
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?
UDPglucose + phenol
UDP + phenyl beta-D-glucoside
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the enzyme is induced by treating with derivatives of cinnamic acid and benzoic acid as stress factor
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?
UDPglucose + salicyl aldehyde
UDP + 2-(beta-D-glucopyranosyloxy)benzaldehyde
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?
UDPglucose + salicyl aldehyde
UDP + 2-(beta-D-glucopyranosyloxy)benzaldehyde
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?
UDPglucose + salicyl aldehyde
UDP + 2-(beta-D-glucopyranosyloxy)benzaldehyde
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?
UDPglucose + salicyl aldehyde
UDP + 2-(beta-D-glucopyranosyloxy)benzaldehyde
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?
UDPglucose + scopoletin
UDP + scopoletin beta-D-glucoside
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UDPxylose also acts as a weak donor
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?
UDPglucose + umbelliferone
UDP + umbelliferyl beta-D-glucoside
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucose + vanillin
UDP + 4-beta-D-glucopyranosyloxy 3-methoxybenzaldehyde
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?
UDPglucuronic acid + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucuronic acid
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?
UDPglucuronic acid + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucuronic acid
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?
UDPglucuronic acid + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucuronic acid
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?
UDPglucuronic acid + p-nitrophenol
dTDP + p-nitrophenyl beta-D-glucuronic acid
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?
additional information
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both UDP-Glc and UDP-Gal are used as sugar donors, with UDP-Glc beinng preferred. The highest catalytic activity is observed toward gallic acid among the C6-C1 substrates and toward p-coumaric acid among the C6-C3 substrates
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additional information
?
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overview: acceptors for D-glucose
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?
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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tetrasaccharide repeats: Glc-Glc-Gal-Man
?
UDPglucose + lipophosphoglycan
UDP + glycosylated lipophosphoglycan
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tetrasaccharide repeats: Glc-Glc-Gal-Man
?
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METALS and IONS
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Mg2+
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Dehydration
Perturbation of indole-3-butyric acid homeostasis by the UDP-glucosyltransferase UGT74E2 modulates Arabidopsis architecture and water stress tolerance.
Infections
Genome-wide survey for baculoviral host homologs using the Bombyx genome sequence.
Infections
Transcriptional profiling of wheat (Triticum aestivum L.) during a compatible interaction with the cereal cyst nematode Heterodera avenae.
Virus Diseases
Proteome profile of maize (Zea Mays L.) leaf tissue at the flowering stage after long-term adjustment to rice black-streaked dwarf virus infection.
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
0.00006
0.0001
0.0002
0.0003
0.0011
0.0012
0.0013
0.0015