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Information on EC 2.4.1.345 - phosphatidyl-myo-inositol alpha-mannosyltransferase

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IUBMB Comments
Requires Mg2+. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
phosphatidyl-myo-inositol mannosyltransferase a, mannosyltransferase pima, phosphatidyl-myo-inositol mannosyltransferase pima, phosphatidylinositol mannosyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
GDP-alpha-D-mannose + 1-phosphatidyl-1D-myo-inositol = GDP + 2-O-(alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol
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transfers one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol
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