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Information on EC 2.4.1.337 - 1,2-diacylglycerol 3-alpha-glucosyltransferase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.337 1,2-diacylglycerol 3-alpha-glucosyltransferase
IUBMB Comments
The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC 2.4.1.336, monoglucosyldiacylglycerol synthase.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
alpha-monoglucosyldiacylglycerol synthase, Atu2297, MGlcDAG synthase, MGS, UDP-glucose-diacylglycerol glucosyltransferase, UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase, UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase, UDP-glucose:1,2-diacylglycerol glucosyltransferase, UDP-glucose:diacylglycerol glucosyltransferase, uridine diphosphoglucose-diacylglycerol glucosyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucose + a 1,2-diacyl-sn-glycerol = UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
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UDP-glucose + 1,2-diacyl-sn-glycerol = UDP + 3-D-glucosyl-1,2-diacyl-sn-glycerol
show the reaction diagram
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