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Information on EC 2.4.1.313 - protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.313
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IUBMB Comments
The human protein is specific for UDP-N-acetyl-alpha-D-galactosamine as donor . The enzyme is involved in the formation of a phosphorylated trisaccharide on a threonine residue of alpha-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains.
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The enzyme appears in viruses and cellular organisms
Synonyms
B3GALNT2, beta 1,3-N-acetylgalactosaminyltransferase2, beta-1,3-N-acetylgalactosaminyltransferase 2, beta1,3-N-acetylgalactosaminyltransferase II, beta1,3-N-acetylgalactosaminyltransferase-II, beta3GalNAc-T2, UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-galactosamine + 3-O-[N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein] = UDP + 3-O-[N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl]-L-threonyl-[protein]
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