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Information on EC 2.4.1.242 - NDP-glucose-starch glucosyltransferase and Organism(s) Sorghum bicolor and UniProt Accession Q43134

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.242 NDP-glucose-starch glucosyltransferase
IUBMB Comments
Unlike EC 2.4.1.11, glycogen(starch) synthase and EC 2.4.1.21, starch synthase, which use UDP-glucose and ADP-glucose, respectively, this enzyme can use either UDP- or ADP-glucose. Mutants that lack the Wx (waxy) allele cannot produce this enzyme, which plays an important role in the normal synthesis of amylose. In such mutants, only amylopectin is produced in the endosperm or pollen .
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Sorghum bicolor
UNIPROT: Q43134
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Word Map
The taxonomic range for the selected organisms is: Sorghum bicolor
The expected taxonomic range for this enzyme is: Eukaryota, Archaea, Bacteria
Synonyms
sgp-1, wx-b1, wx-a1, waxy protein, gbss1, wx-d1, gbssii, wx protein, gbss i, granule bound starch synthase i, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
granule-bound starch synthase
-
Waxy protein
-
SYSTEMATIC NAME
IUBMB Comments
NDP-glucose:(1->4)-alpha-D-glucan 4-alpha-D-glucosyltransferase
Unlike EC 2.4.1.11, glycogen(starch) synthase and EC 2.4.1.21, starch synthase, which use UDP-glucose and ADP-glucose, respectively, this enzyme can use either UDP- or ADP-glucose. Mutants that lack the Wx (waxy) allele cannot produce this enzyme, which plays an important role in the normal synthesis of amylose. In such mutants, only amylopectin is produced in the endosperm [3] or pollen [5].
CAS REGISTRY NUMBER
COMMENTARY hide
9031-53-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
lines B 9307, B Tx630, B TxARG1, B Wheatland, R Tx2907, and R Tx430
UniProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
starch granule
-
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
loss of GBSS activity results in starch granules containing mostly amylopectin and little or no amylose (phenotype waxy)
physiological function
responsible for amylose synthesis in starch granules
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SSG1_SORBI
608
0
66074
Swiss-Prot
Chloroplast (Reliability: 3)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Q268H
the mutation results in the phenotype described as waxy
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sattler, S.; Singh, J.; Haas, E.; Guo, L.; Sarath, G.; Pedersen, J.
Two distinct waxy alleles impact the granule-bound starch synthase in sorghum
Mol. Breed.
24
349-359
2009
Sorghum bicolor (Q43134)
Manually annotated by BRENDA team