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Information on EC 2.4.1.165 - N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase

for references in articles please use BRENDA:EC2.4.1.165
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IUBMB Comments
Requires Mn2+. Only substances containing sialic acid residues can act as acceptors; bovine fetuin is the best acceptor tested.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
galgt2, beta4galnact-ii, ct galnac transferase, beta4galnac-t, udp-galnac:beta1,4-n-acetylgalactosaminyltransferase, beta-1,4-n-acetylgalactosyltransferase ii, cytotoxic t cell galnac transferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-N-acetyl-alpha-D-galactosamine + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-[alpha-N-acetylneuraminyl-(2->3)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
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