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Information on EC 2.4.1.152 - 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase and Organism(s) Pan troglodytes and UniProt Accession P56434

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EC Tree
IUBMB Comments
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
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This record set is specific for:
Pan troglodytes
UNIPROT: P56434
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Word Map
The taxonomic range for the selected organisms is: Pan troglodytes
The enzyme appears in selected viruses and cellular organisms
Synonyms
fuc-tv, alpha-3-fucosyltransferase, fucosyltransferase 4, alpha-3-l-fucosyltransferase, alpha1,3 fuct-vii, fut vi, alpha1,3ft, alpha1,3-fuct, fucosyltransferase-vii, fucosyltransferase ix, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
alpha(1-3)fucosyltransferase
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-
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alpha-3-fucosyltransferase
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-
-
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alpha-3-L-fucosyltransferase
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-
-
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alpha1,3 fucosyltransferase
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-
-
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alpha1,3FT
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-
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alpha1-3 fucosyltransferase
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-
-
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alpha1->3fucosyltransferase
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-
-
-
alpha3-fucosyltransferase-V
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-
-
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alpha3-fucosyltransferase-VI
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-
-
-
Fuc-Tb
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-
-
-
Fuc-TV
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-
-
-
fucosyltransferase, guanosine diphosphofucose-glucoside alpha1-->3-
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-
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FucT-VI
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-
-
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FUT5
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-
-
-
FUT6
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-
-
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galactoside 3-fucosyltransferase
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-
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GDL-L-fucose:N-acetyl-beta-D-glucosaminyl alpha-3-L-fucosyltransferase
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-
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GDP-Fuc:Galbeta1-4GlcNAc (Fuc to GlcNAc) alpha1-3 fucosyltransferase
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-
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GDP-fucose:beta-D-N-acetylglucosaminide 3-alpha-fucosyltransferase
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GDP-fucose:Galbeta(1-4)GlcNAc-R alpha(1-3)fucosyltransferase
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GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-galactosaminyl-R 3-L-fucosyltransferase
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guanosine diphosphofucose glucoside alpha1->3fucosyltransferase
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lewis-negative alpha-3-fucosyltransferase
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plasma alpha-3-fucosyltransferase
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-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
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-
-
-
SYSTEMATIC NAME
IUBMB Comments
GDP-beta-L-fucose:beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase (configuration-inverting)
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3.
CAS REGISTRY NUMBER
COMMENTARY hide
111310-38-4
-
39279-34-0
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
type II membrane protein, membrane-bound form in trans cistermae of Golgi
Manually annotated by BRENDA team
type II membrane protein, membrane-bound form in trans cistermae of Golgi
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
FUT6_PANTR
359
1
41893
Swiss-Prot
Secretory Pathway (Reliability: 1)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
41892
1 * 41892, calculation from nucleotide sequence
43034
1 * 43034, calculation from nucleotide sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
monomer
1 * 41892, calculation from nucleotide sequence
monomer
1 * 43034, calculation from nucleotide sequence
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Costache, M.; Apoil, P.A.; Cailleau, A.; Elmgren, A.; Larson, G.; Henry, S.; Blancher, A.; Iordachescu, D.; Oriol, R.; Mollicone, R.
Evolution of fucosyltransferase genes in vertebrates
J. Biol. Chem.
272
29721-29728
1997
Pan troglodytes (P56433), Pan troglodytes (P56434)
Manually annotated by BRENDA team