Information on EC 2.4.1.14 - sucrose-phosphate synthase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.14 sucrose-phosphate synthase
IUBMB Comments
Requires Mg2+ or Mn2+ for maximal activity . The enzyme from Synechocystis sp. strain PCC 6803 is not specific for UDP-glucose as it can use ADP-glucose and, to a lesser extent, GDP-glucose as substrates . The enzyme from rice leaves is activated by glucose 6-phosphate but that from cyanobacterial species is not . While the reaction catalysed by this enzyme is reversible, the enzyme usually works in concert with EC 3.1.3.24, sucrose-phosphate phosphatase, to form sucrose, making the above reaction essentially irreversible . The F in sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
At5g20280, AtSPS, More, SPS, SPS A, SPS1, SPS11, Sps2, SPS4, SPS6, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
UDP-alpha-D-glucose + D-fructose 6-phosphate = UDP + sucrose 6F-phosphate
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