Any feedback?
Information on EC 2.4.1.13 - sucrose synthase and Organism(s) Vicia faba and UniProt Accession P31926
for references in articles please use BRENDA:EC2.4.1.13Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
2.4.1.13 sucrose synthaseIUBMB Comments
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) .
Specify your search results
Word Map
- 2.4.1.13
- invertase
- starch
- maize
-
sink
- cultivar
-
pyrophosphorylase
- grain
- endosperm
- crop
- seedling
- cellulose
- potato
- cotton
- tuber
- drought
- phloem
-
sucrose-phosphate
- fructokinase
- kernel
- hexoses
- hexokinase
- agpase
-
3.2.1.26
-
anthesis
- callose
- hirsutum
- sugarcane
-
photosynthate
- panicle
- fructans
-
granule-bound
-
gossypium
-
grain-filling
-
photoassimilate
- adpglucose
- spikelet
-
source-sink
-
boll
- saccharum
- synthesis
- stachyose
-
amyloplasts
- taproot
- agriculture
The taxonomic range for the selected organisms is: Vicia faba
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
sucrose synthase, sucrose synthetase, mtsucs1, susy1, rsus3, sucrose synthase 1, psnsusy2, susy2, sucrose synthase 2, sucrose synthase 3, 
more
topSYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
glucosyltransferase, uridine diphosphoglucose-fructose
-
-
-
-
sucrose synthetase
-
-
-
-
sucrose-UDP glucosyltransferase
-
-
-
-
sucrose-uridine diphosphate glucosyltransferase
-
-
-
-
Sus
-
-
-
-
SuSy
UDP-glucose-fructose glucosyltransferase
-
-
-
-
UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
-
-
-
-
uridine diphosphoglucose-fructose glucosyltransferase
-
-
-
-
SuSy
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
-
-
-
-
PATHWAY SOURCE
PATHWAYS
BRENDA
-
-
SYSTEMATIC NAME
IUBMB Comments
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
CAS REGISTRY NUMBER
COMMENTARY
9030-05-1
-
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
NDP + sucrose
NDP-alpha-D-glucose + D-fructose
-
the reaction is catalyzed at low pH values
-
-
r
NDP-alpha-D-glucose + D-fructose
NDP + sucrose
-
the reaction is catalyzed at high pH values
-
-
r
additional information
?
-
-
sucrose synthase appears to be largely responsible for feeding assimilated carbon into sink metabolism
-
-
?
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
NDP + sucrose
NDP-alpha-D-glucose + D-fructose
-
the reaction is catalyzed at low pH values
-
-
r
NDP-alpha-D-glucose + D-fructose
NDP + sucrose
-
the reaction is catalyzed at high pH values
-
-
r
additional information
?
-
-
sucrose synthase appears to be largely responsible for feeding assimilated carbon into sink metabolism
-
-
?
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
6-Dimethylaminopurine
sucrose-induced activity of sucrose synthase is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities
okadaic acid
sucrose-induced activity of sucrose synthase is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
physiological function
in sugar-starved cells, the in situ activity of both sucrose synthase and invertase decrease significantly. Following supplementation of root meristems with sugar, invertase remaines inactive, but sucrose synthase activity increases. In sugar-starved cells, sucrose synthase activity is induced more by exogenous sucrose than by glucose. The sucrose-induced activity is strongly inhibited by okadaic acid and less by 6-dimethylaminopurine at early stages of regeneration, but not at the stages preceding DNA replication or mitotic activities. Prolongation of regeneration and a marked decrease in the number of cells resuming proliferation and resulting from the action of inhibitors, are correlated with the process of sucrose synthase activation at the beginning of regeneration from sugar starvation
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). SUS_VICFA
806
0
92521
Swiss-Prot
other Location (Reliability: 5)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
DNA and amino acid sequence determination and analysis, phylogenetic analysis
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ross, H.A.; Davies, H.V.
Purification and characterization of sucrose synthase from the cotyledons of Vicia faba L.
Plant Physiol.
100
1008-1013
1992
Vicia faba
Weber, H.; Buchner, P.; Borisjuk, L.; Wobus, U.
Sucrose metabolism during cotyledon development of Vicia faba l. is controlled by the concerted action of both sucrose-phosphate synthase and sucrose synthase: Expression patterns, metabolic regulation and implications for seed development
Plant J.
9
841-850
1996
Vicia faba
Sturm, A.; Tang, G.Q.
The sucrose-cleaving enzymes of plants are crucial for development, growth and carbon partitioning
Trends Plant Sci.
4
401-407
1999
Vicia faba, Daucus carota, Zea mays
Abid, G.; Silue, S.; Muhovski, Y.; Jacquemin, J.M.; Toussaint, A.; Baudoin, J.P.
Role of myo-inositol phosphate synthase and sucrose synthase genes in plant seed development
Gene
439
1-10
2009
Arabidopsis thaliana (F4K5W8), Arabidopsis thaliana (P49040), Arabidopsis thaliana (Q00917), Citrus unshiu (Q9SLY2), Citrus x paradisi, Coffea arabica (Q0E7D4), Daucus carota (O49845), Eucalyptus grandis (Q00P15), Eucalyptus grandis (Q00P16), Glycine max (P13708), Glycine max, Gossypium hirsutum (Q9XGB7), Gossypium hirsutum, Oryza sativa (P31924), Pisum sativum (O24301), Pisum sativum (O81610), Pisum sativum (Q9AVR8), Pisum sativum (Q9T0M9), Solanum lycopersicum (P49037), Solanum tuberosum (Q84T18), Vicia faba (P31926), Zea mays
Polit, J.T.; Ciereszko, I.
Sucrose synthase activity and carbohydrates content in relation to phosphorylation status of Vicia faba root meristems during reactivation from sugar depletion
J. Plant Physiol.
169
1597-1606
2012
Vicia faba (P31926), Vicia faba
Schmoelzer, K.; Gutmann, A.; Diricks, M.; Desmet, T.; Nidetzky, B.
Sucrose synthase A unique glycosyltransferase for biocatalytic glycosylation process development
Biotechnol. Adv.
34
88-111
2016
Anabaena sp., Arabidopsis thaliana, Beta vulgaris, Vicia faba, Helianthus tuberosus, Hordeum vulgare, Ipomoea batatas, Manihot esculenta, Nitrosomonas europaea, Oryza sativa, Vigna radiata, Pisum sativum, Prunus persica, Pyrus pyrifolia, Saccharum sp., Solanum tuberosum, Zea mays, Thermosynechococcus vestitus, Acidithiobacillus caldus, Solanum chmielewskii, Glycine max (P13708)
EXTERNAL LINKS (specific for EC-Number 2.4.1.13)
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
