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Information on EC 2.4.1.13 - sucrose synthase and Organism(s) Saccharum officinarum and UniProt Accession P31925

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.13 sucrose synthase
IUBMB Comments
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) .
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This record set is specific for:
Saccharum officinarum
UNIPROT: P31925
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Word Map
The taxonomic range for the selected organisms is: Saccharum officinarum
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
sucrose synthase, sucrose synthetase, susy1, mtsucs1, rsus3, sucrose synthase 1, psnsusy2, susy2, sucrose synthase 2, sucrose synthase 3, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
glucosyltransferase, uridine diphosphoglucose-fructose
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-
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sucrose synthetase
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sucrose-UDP glucosyltransferase
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-
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sucrose-uridine diphosphate glucosyltransferase
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Sus
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UDP-glucose-fructose glucosyltransferase
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UDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
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uridine diphosphoglucose-fructose glucosyltransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
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SYSTEMATIC NAME
IUBMB Comments
NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose [3-9]. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis) [10].
CAS REGISTRY NUMBER
COMMENTARY hide
9030-05-1
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP + sucrose
UDP-glucose + D-fructose
show the reaction diagram
UDPglucose + D-fructose
UDP + sucrose
show the reaction diagram
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-
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r
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
UDP + sucrose
UDP-glucose + D-fructose
show the reaction diagram
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major enzyme of sucrose synthesis
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r
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Mg2+
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activation
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
6.49 - 11.7
D-fructose
35.9 - 109
sucrose
0.00191 - 1.07
UDP
0.234 - 3.59
UDP-glucose
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
enzymic activity is higher in immature internodes than in mature internodes in all cultivars, sucrose synthase transcript expression shows a similar pattern. Sucrose synthase activity is negatively correlated with sucrose and positively correlated with hexose sugars
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
sucrose synthase activity is negatively correlated with sucrose and positively correlated with hexose sugars
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
SUS_SACOF
218
0
25349
Swiss-Prot
other Location (Reliability: 3)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
94000
-
4 * 94000, SuSyA, SuSyB or SuSyC, SDS-PAGE
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tetramer
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4 * 94000, SuSyA, SuSyB or SuSyC, SDS-PAGE
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
enzymic activity is higher in immature internodes than in mature internodes in all cultivars, sucrose synthase transcript expression shows a similar pattern. Sucrose synthase activity is negatively correlated with sucrose and positively correlated with hexose sugars
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Patil, B.A.; Joshi, G.V.
Effect of magnesium(2+) and manganese(2+) ions on sucrose synthetase in sugarcane leaves
Proc. Indian Natl. Sci. Acad. Part B
38
50-54
1972
Saccharum officinarum
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Manually annotated by BRENDA team
Schafer, W.E.; Rohwer, J.M.; Botha, F.C.
Partial purification and characterisation of sucrose synthase in sugarcane
J. Plant Physiol.
162
11-20
2005
Saccharum officinarum
Manually annotated by BRENDA team
Verma, A.K.; Upadhyay, S.K.; Verma, P.C.; Solomon, S.; Singh, S.B.
Functional analysis of sucrose phosphate synthase (SPS) and sucrose synthase (SS) in sugarcane (Saccharum) cultivars
Plant Biol.
13
325-332
2011
Saccharum officinarum (P31925), Saccharum officinarum
Manually annotated by BRENDA team