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Information on EC 2.4.1.118 - cytokinin 7-beta-glucosyltransferase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9FIA0

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.118 cytokinin 7-beta-glucosyltransferase
IUBMB Comments
Acts on a range of N6-substituted adenines, including zeatin and N6-benzylaminopurine, but not N6-benzyladenine. With some acceptors, 9-beta-D-glucosides are also formed.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9FIA0
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The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
cytokinin 7-glucosyltransferase, glucosyltransferase, uridine diphosphoglucose-zeatin 7-, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
cytokinin 7-glucosyltransferase
-
-
-
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glucosyltransferase, uridine diphosphoglucose-zeatin 7-
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hexosyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:N6-alkylaminopurine 7-glucosyltransferase
Acts on a range of N6-substituted adenines, including zeatin and N6-benzylaminopurine, but not N6-benzyladenine. With some acceptors, 9-beta-D-glucosides are also formed.
CAS REGISTRY NUMBER
COMMENTARY hide
72103-03-8
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
dihydrozeatin + TDP-glucose
dihydrozeatin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
kinetin + TDP-glucose
kinetin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
N6-benzyladenine + TDP-glucose
N6-benzyladenine 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
N6-isopentenyladenine + TDP-glucose
N6-isopentenyladenine 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
trans-zeatin + TDP-glucose
trans-zeatin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
dihydrozeatin + TDP-glucose
dihydrozeatin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
kinetin + TDP-glucose
kinetin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
N6-benzyladenine + TDP-glucose
N6-benzyladenine 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
N6-isopentenyladenine + TDP-glucose
N6-isopentenyladenine 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
trans-zeatin + TDP-glucose
trans-zeatin 7-beta-D-glucoside + TDP
show the reaction diagram
-
-
-
?
additional information
?
-
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione
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3-isobutyl-1-methylxanthine
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.22
dihydrozeatin
pH 8.0, 30°C
0.07
kinetin
pH 8.0, 30°C
0.04
N6-benzyladenine
pH 8.0, 30°C
0.07
N6-isopentenyladenine
pH 8.0, 30°C
0.22
trans-zeatin
pH 8.0, 30°C
0.16
dihydrozeatin
pH 8.0, 30°C
0.21
kinetin
pH 8.0, 30°C
0.09
N6-benzyladenine
pH 8.0, 30°C
0.13
N6-isopentenyladenine
pH 8.0, 30°C
0.24
trans-zeatin
pH 8.0, 30°C
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0025
Olomoucine
pH 8.0, 30°C
0.0016
Olomoucine
pH 8.0, 30°C
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
isoform UGT76C2
Swissprot
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
U76C2_ARATH
450
0
50425
Swiss-Prot
-
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hou, B.; Lim, E.K.; Higgins, G.S.; Bowles, D.J.
N-Glucosylation of cytokinins by glycosyltransferases of Arabidopsis thaliana
J. Biol. Chem.
279
47822-47832
2004
Arabidopsis thaliana (Q9FI99), Arabidopsis thaliana (Q9FIA0)
Manually annotated by BRENDA team