Any feedback?
Information on EC 2.4.1.111 - coniferyl-alcohol glucosyltransferase
for references in articles please use BRENDA:EC2.4.1.111Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
2.4.1.111 coniferyl-alcohol glucosyltransferaseIUBMB Comments
Sinapyl alcohol can also act as acceptor.
Specify your search results
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
udp-glucose coniferyl alcohol glucosyltransferase, 
more
topPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
CAGT
-
-
-
-
glucosyltransferase, uridine diphosphoglucose-coniferyl alcohol
-
-
-
-
UDP-glucose coniferyl alcohol glucosyltransferase
-
-
-
-
uridine diphosphoglucose-coniferyl alcohol glucosyltransferase
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
UDP-glucose + coniferyl alcohol = UDP + coniferin
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
hexosyl group transfer
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY SOURCE
PATHWAYS
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SYSTEMATIC NAME
IUBMB Comments
UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase
Sinapyl alcohol can also act as acceptor.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
CAS REGISTRY NUMBER
COMMENTARY
61116-23-2
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-glucose + quercetin
UDP + quercetin 7-O-beta-D-glucoside
-
glucosylated at 22% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + caffeic acid
UDP + ?
-
glucosylated at 18% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + scopoletin
UDP + scopoletin-7-O-beta-D-glucopyranoside
-
glucosylated at 10% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + vanillic acid
UDP + vanillic acid-4-O-beta-D-glucopyranoside
-
glucosylated at 14% of the activity with coniferyl alcohol
-
-
?
additional information
?
-
-
TDPglucose can replace UDPglucose with 17% efficiency
-
-
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
Z-coniferyl alcohol is readily converted into Z-coniferin. E-coniferyl alcohol is only poorly converted into E-coniferin
Z-coniferyl alcohol is readily converted into Z-coniferin. E-coniferyl alcohol is only poorly converted into E-coniferin
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
forward reaction is about six times faster than the reverse reaction
-
-
r
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl alcohol
UDP + coniferin
-
-
i.e. coniferyl alcohol 7-O-beta-D-glucopyranoside
?
UDP-glucose + coniferyl aldehyde
UDP + coniferaldehyde-4-O-beta-D-glucopyranoside
-
glucosylated at 63% the rate of coniferyl alcohol
-
-
?
UDP-glucose + coniferyl aldehyde
UDP + coniferaldehyde-4-O-beta-D-glucopyranoside
-
-
-
?
UDP-glucose + coniferyl aldehyde
UDP + coniferaldehyde-4-O-beta-D-glucopyranoside
-
glucosylated at 46% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + ferulic acid
UDP + ferulic acid-4-O-beta-D-glucopyranoside
-
-
-
-
?
UDP-glucose + ferulic acid
UDP + ferulic acid-4-O-beta-D-glucopyranoside
-
glucosylated at 20% of the activitry with coniferyl alcohol
-
-
?
UDP-glucose + isorhamnetin
UDP + isorhamnetin 7-O-beta-D-glucopyranoside
-
glucosylated at 18% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + isorhamnetin
UDP + isorhamnetin 7-O-beta-D-glucopyranoside
-
glucosylated at 22% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + scopoletin
UDP + scopoletin 7-O-beta-D-glucopyranoside
-
-
-
-
?
UDP-glucose + sinapaldehyde
UDP + sinapaldehyde-4-O-beta-D-glucopyranoside
-
glucosylated at 82% the rate of coniferyl alcohol
-
-
?
UDP-glucose + sinapaldehyde
UDP + sinapaldehyde-4-O-beta-D-glucopyranoside
-
glucosylated at 48% the rate of coniferyl alcohol
-
-
?
UDP-glucose + sinapaldehyde
UDP + sinapaldehyde-4-O-beta-D-glucopyranoside
-
-
-
?
UDP-glucose + sinapic acid
UDP + ?
-
glucosylated at 14% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + sinapic acid
UDP + ?
-
glucosylated at 21% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + sinapyl alcohol
UDP + syringin
-
glucosylated at 82% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + sinapyl alcohol
UDP + syringin
-
glucosylated at 14% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + sinapyl alcohol
UDP + syringin
-
glucosylated at 96% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + sinapyl alcohol
UDP + syringin
-
glucosylated at 74% of the activity with coniferyl alcohol
-
-
?
UDP-glucose + vanillin
UDP + vanillin-4-O-beta-D-glucopyranoside
-
glucosylated at 17% of the activity with coniferyl alcohol
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
participates in lignification of spruce
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
the role of this enzyme is believed to catalyze the transfer of glucose from UDPglucose to coniferyl or sinapyl alcohol as storage intermediates in lignin biosynthesis
-
-
?
UDPglucose + coniferyl alcohol
?
-
participates in lignification of spruce
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
7.5
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
5.5 - 8.2
-
pH 5.5: about 50% of maximal activity, pH 8.2: about 70% of maximal activity, phosphate buffer
6.5 - 8.2
-
about half-maximal activity at pH 6.5 and 83% of maximal activity at pH 8.2, Tris buffer
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
TEMPERATURE RANGE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
-
predominantly located in epidermal and subepidermal layers, vascular bundles
brenda
-
during dormancy activity is not detected in the cambium. Enzyme becomes weakly active in springtime when fusiform cells of the lateral meristem changed from densely protoplasmic to highly vacuolated states, just prior to resumption of cell-division activity. During cambial growth and xylogenesis enzyme activity in cambial derivatives is greater than that found in the cambial zone. Activity disappears when the cambium enters dormancy in August, prior to completion of lignification in the last differentiating latewood tracheids
brenda
-
initialization in the cambium in early spring with resumption of cell division activity, not detectable in the early autumn at the time when cell division has ceased and wood formation is still occuring
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). U72E2_ARATH
481
0
52992
Swiss-Prot
other Location (Reliability: 3)
U72E3_ARATH
481
0
52904
Swiss-Prot
other Location (Reliability: 3)
A0A0B2R6P8_GLYSO
465
0
52761
TrEMBL
other Location (Reliability: 4)
A0A2I0A0T3_9ASPA
318
0
33608
TrEMBL
Chloroplast (Reliability: 3)
A0A0B2QX72_GLYSO
78
0
8720
TrEMBL
other Location (Reliability: 3)
A0A0B2R8C9_GLYSO
116
0
13312
TrEMBL
Secretory Pathway (Reliability: 3)
A0A7C9ADQ7_OPUST
107
0
12097
TrEMBL
other Location (Reliability: 4)
A0A151TY47_CAJCA
165
0
18892
TrEMBL
Chloroplast (Reliability: 5)
A0A0B2QSM4_GLYSO
235
0
26017
TrEMBL
other Location (Reliability: 2)
A0A0B2QYP7_GLYSO
398
0
44380
TrEMBL
other Location (Reliability: 5)
A0A0B2QXX0_GLYSO
617
0
67574
TrEMBL
other Location (Reliability: 5)
A0A151RG82_CAJCA
473
0
52389
TrEMBL
other Location (Reliability: 2)
A0A151T8Z9_CAJCA
300
0
33593
TrEMBL
Secretory Pathway (Reliability: 5)
A0A7C9AFI0_OPUST
114
0
12890
TrEMBL
Secretory Pathway (Reliability: 5)
A0A151QZ32_CAJCA
457
0
51264
TrEMBL
other Location (Reliability: 5)
A0A151TU26_CAJCA
335
0
38084
TrEMBL
other Location (Reliability: 4)
A0A0B2RYJ0_GLYSO
360
0
39779
TrEMBL
other Location (Reliability: 3)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
addition of high molarity buffer, 200 mM Tris/HCl, or 2-mercaptoethanol, optimal concentration 42 mM, increases stability considerably
-
in dilute solutions addition of 10-20% glycerol or ethylene glycol increases stability
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, addition of 28 mM 2-mercaptoethanol and 10% ethyleneglycol are required for stability, about 20% loss of activity within several weeks
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ibrahim, R.K.; Grisebach, H.
Purification and properties of UDP-glucose: coniferyl alcohol glucosyltransferase from suspension cultures of Pauls scarlet rose
Arch. Biochem. Biophys.
176
700-708
1976
Cicer arietinum, Glycine max, Linum usitatissimum, Nicotiana tabacum, Parthenocissus tricuspidata, Petroselinum crispum, Rosa sp.
brenda
Schmid, G.; Hammer, D.K.; Ritterbusch, A.; Grisebach, H.
Appearance and immunohistochemical localization of UDP-glucose:coniferyl alcohol glucosyltransferase in spruce (Picea albies (L.) Karst.) Seedlings
Planta
156
207-212
1982
Picea abies
brenda
Schmid, G.; Grisebach, H.
Enzymic synthesis of lignin precursors. Purification and properties of UDP glucose: coniferyl-alcohol glucosyltransferase from cambial sap of spruce (Picea abies L.)
Eur. J. Biochem.
123
363-370
1982
Picea abies
brenda
Ibrahim, R.K.
Glucosylation of lignin precursors by uridine diphosphate glucose. Coniferyl alcohol glucosyltransferase in higher plants
Z. Pflanzenphysiol.
85
253-262
1977
Forsythia ovata
-
brenda
Steeves, V.; Foerster, H.; Pommer, U.; Savidge, R.
Coniferyl alcohol metabolism in conifers. I. Glucosidic turnover of cinnamyl aldehydes by UDPG: coniferyl alcohol glucosyltransferase from pine cambium
Phytochemistry
57
1085-1093
2001
Pinus strobus
brenda
Yamamoto, E.; Inciong, M.E.J.; Davin, L.B.; Lewis, N.G.
Formation of cis-coniferin in cell-free extracts of Fagus grandifolia ehrh bark
Plant Physiol.
94
209-213
1990
Fagus grandifolia
brenda
Savidge, R.A.; Foerster, H.
Seasonal activity of uridine 5'-diphosphoglucose:coniferyl alcohol glucosyltransferase in relation to cambial growth and dormancy in conifers
Can. J. Bot.
76
486-493
1998
Pinus banksiana
-
brenda
Foerster, H.; Savidge, R.A.
Characterization and seasonal activity of UDPG: coniferyl alcohol glucosyl transferase linked to cambial growth in jack pine
Proc. Plant Growth Reg. Soc. Am.
22nd
402-407
1995
Pinus banksiana
-
brenda
Select items on the left to see more content.
EXTERNAL LINKS (specific for EC-Number 2.4.1.111)
html completed
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
About BRENDA
Social media
Help
Survey
Download
Contribution
Legal
Curated at
Member of
