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Information on EC 2.4.1.109 - dolichyl-phosphate-mannose-protein mannosyltransferase

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IUBMB Comments
The enzyme transfers mannosyl residues to the hydroxy group of serine or threonine residues, producing cell-wall mannoproteins. It acts only on long-chain alpha-dihydropolyprenyl derivatives, larger than C35.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
pomt1, pomt2, protein o-mannosyltransferase, pmt1p, o-mannosyltransferase, pmt2p, protein o-mannosyltransferase 1, protein mannosyltransferases, pmt4p, aapmta, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] = dolichyl phosphate + 3-O-(alpha-D-mannosyl)-L-seryl-[protein]
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(2)
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dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] = dolichyl phosphate + 3-O-(alpha-D-mannosyl)-L-threonyl-[protein]
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