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Information on EC 2.3.3.14 - homocitrate synthase and Organism(s) Nostoc sp. and UniProt Accession P58637

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.3 Acyl groups converted into alkyl groups on transfer
                2.3.3.14 homocitrate synthase
IUBMB Comments
Belongs in the alpha-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36, homoaconitate hydratase. The enzyme also acts with oxaloacetate as substrate, but more slowly [2,3].
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This record set is specific for:
Nostoc sp.
UNIPROT: P58637
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Word Map
  • 2.3.3.14
  • gyrus
  • resting-state
  • frontal
  • deficit
  • sclerosis
  • cingulate
  • schizophrenia
  • hair
  • emotional
  • prefrontal
  • inferior
  • anxiety
  • bipolar
  • neuropsychological
  • auditory
  • parietal
  • insula
  • neuroimaging
  • occipital
  • default
  • precuneus
  • high-content
  • verbal
  • cochlea
  • putamen
  • whole-brain
  • tensor
  • voxel-based
  • precentral
  • nervosa
  • first-episode
  • relapsing-remitting
  • obsessive-compulsive
  • salience
  • hemichannels
  • t1-weighted
  • orbitofrontal
  • dlpfc
  • visuospatial
  • unmedicated
  • parahippocampal
  • impulsivity
  • event-related
  • fluency
  • fasciculus
  • connectome
  • tractography
  • peripapillary
  • euthymic
  • stroop
  • biotechnology
  • synthesis
  • medicine
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
hcs, homocitrate synthase, lys22, nifv2, sphcs, tthcs, lys21p, homocitrate synthetase, lys22p, saci_1304, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)
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acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase
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HCS
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homocitrate synthetase
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homocitrate-condensing enzyme
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homocondensing enzyme
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synthase, homocitrate
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
condensation
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SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Belongs in the alpha-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36, homoaconitate hydratase. The enzyme also acts with oxaloacetate as substrate, but more slowly [2,3].
CAS REGISTRY NUMBER
COMMENTARY hide
9075-60-9
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