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2-amino-5-(butan-2-ylamino)-5-oxopentanoic acid
?
-
-
-
-
?
2-amino-5-(cyclohexylamino)-5-oxopentanoic acid
?
-
-
-
-
?
2-amino-5-(cyclopropylamino)-5-oxopentanoic acid
?
-
-
-
-
?
2-amino-5-oxo-5-(propan-2-ylamino)pentanoic acid
?
-
-
-
-
?
2-amino-5-oxo-5-[(2-phenylethyl)amino]pentanoic acid
?
-
-
-
-
?
2-amino-5-[(2-methylbutyl)amino]-5-oxopentanoic acid
?
-
-
-
-
?
2-amino-5-[(2S)-butan-2-ylamino]-5-oxopentanoic acid
?
-
-
-
-
?
2-amino-5-[[(2S)-2-methylbutyl]amino]-5-oxopentanoic acid
?
-
-
-
-
?
39SrpL21 protein
?
-
-
-
?
amyloid beta(3-40)
pyroglutamyl-amyloid beta(3-40) + NH3
-
-
-
-
?
amyloid peptide Abeta(3-40,42)
Abeta(3[pE]-40,42) + H2O
-
-
-
?
amyloid peptide Abeta(3-40/42)
pGluAbeta(3-40/42) + H2O
-
-
significant portion of Abeta peptides of amyloid plaques in Alzheimer's disease brains
-
?
EFRHHDSGYE-NH2
pEFRHHDSGYE-NH2 + H2O
Gln
L-5-oxoproline + NH3
-
-
-
-
?
Gln
pyroglutamate + NH3
-
-
-
-
?
Gln(3)-amyloid-beta peptide 3-11 amide
?
-
-
-
-
?
Gln(3)-amyloid-beta peptide 3-21 amide
?
-
-
-
-
?
Gln(3)-amyloid-beta peptide 3-40 amide
?
-
-
-
-
?
Gln-2-naphthylamide
2-oxoprolyl-2-naphthylamide + NH3
-
-
-
-
?
Gln-2-naphthylamide
pyroglutamyl-2-naphthylamide + NH3
-
-
-
-
?
Gln-4-methylcoumarinylamide
2-oxoprolyl-4-methylcoumarinylamide + NH3
-
-
-
-
?
Gln-7-amido-4-methylcoumarin
L-pyroglutamyl-4-methylcoumarin-7-amide + NH3
-
-
-
-
?
Gln-7-amido-4-methylcoumarin
pyroglutamic acid-7-amido-4-methylcoumarin + NH3
Gln-Ala
pyroglutamic acid-Ala + NH3
Gln-Ala-Ala-Ala-Ala-NH2
pyroglutamic acid-Ala-Ala-Ala-Ala-NH2 + NH3
Gln-Ala-Ala-NH2
pyroglutamic acid-Ala-Ala-NH2 + NH3
Gln-Ala-Ala-Ser-Ala-Ala-NH2
pyroglutamic acid-Ala-Ala-Ser-Ala-Ala-NH2 + NH3
Gln-Arg-Gly-Ile-NH2
pyroglutamic acid-Arg-Gly-Ile-NH2 + NH3
Gln-Arg-Tyr-Phe-NH2
pyroglutamic acid-Arg-Tyr-Phe-NH2 + NH3
Gln-Asn-Gly-Ile-NH2
pyroglutamic acid-Asn-Gly-Ile-NH2 + NH3
Gln-beta-naphthylamide
pyroglutamic acid-beta-naphthylamide + NH3
-
-
-
-
?
Gln-beta-naphthylamide
pyroglutamic acid-beta-naphthylamine + NH3
-
-
-
-
?
Gln-Gln
5-oxoprolyl-Gln + NH3
Gln-Gln
L-5-oxoprolyl-Gln + NH3
-
-
-
-
?
Gln-Gln
pyroglutamic acid-Gln + NH3
Gln-Gln
pyroglutamyl-Gln + NH3
-
-
-
-
?
Gln-Gln-Gln
Glp-Gln-Gln + NH3
Gln-Gln-Tyr-Phe-NH2
pyroglutamic acid-Gln-Tyr-Phe-NH2 + NH3
Gln-Glu
pyroglutamic acid-Glu + NH3
Gln-Glu-Ala-Ala-NH2
pyroglutamic acid-Glu-Ala-Ala-NH2 + NH3
Gln-Glu-Ala-Phe-NH2
pyroglutamic acid-Glu-Ala-Phe-NH2 + NH3
Gln-Glu-Asp-Leu-NH2
pyroglutamic acid-Glu-Asp-Leu-NH2 + NH3
Gln-Glu-Tyr-Ala-NH2
pyroglutamic acid-Glu-Tyr-Ala-NH2 + NH3
Gln-Glu-Tyr-NH2
pyroglutamic acid-Glu-Tyr-NH2 + NH3
Gln-Glu-Tyr-Phe-NH2
pyroglutamic acid-Glu-Tyr-Phe-NH2 + NH3
Gln-Gly
5-oxoprolyl-Gly + NH3
Gln-Gly
pyroglutamic acid-Gly + NH3
Gln-Gly-Pro
Glp-Gly-Pro + NH3
-
-
-
-
?
Gln-Gly-Pro
pGlu-Gly-Pro + NH3
Gln-Gly-Pro
pyroglutamic acid-Gly-Pro + NH3
Gln-His-Pro
pyroglutamyl-His-Pro
-
-
-
-
?
Gln-His-Pro-NH2
L-5-oxoprolyl-His-Pro-NH2 + NH3
-
-
-
-
?
Gln-His-Tyr-Phe-NH2
pyroglutamic acid-His-Tyr-Phe-NH2 + NH3
Gln-Lys-Arg-Leu-NH2
pyroglutamic acid-Lys-Arg-Leu-NH2 + NH3
Gln-Phe-Ala
pGlu-Phe-Ala + NH3
Gln-Phe-Ala-NH2
pyroglutamic acid-Phe-Ala-NH2 + NH3
Gln-Pro-Tyr-Phe-NH2
pyroglutamic acid-Pro-Tyr-Phe-NH2 + NH3
Gln-Ser-Tyr-Phe-NH2
pyroglutamic acid-Ser-Tyr-Phe-NH2 + NH3
Gln-tert-butyl ester
pyroglutamyl-tert-butyl ester + NH3
Gln-Trp-Ala-NH2
pyroglutamic acid-Trp-Ala-NH2 + NH3
Gln-Tyr
pyroglutamic acid-Tyr + NH3
-
-
-
-
?
Gln-Tyr-Ala
pGlu-Tyr-Ala + NH3
Gln-Tyr-Ala
pyroglutamic acid-Tyr-Ala + NH3
Gln-Tyr-Ala-OH
L-5-oxoprolyl-Tyr-Ala + NH3
-
-
-
-
?
Gln-Val
Glp-Val + NH3
-
-
-
-
?
Gln-Val
pyroglutamic acid-Val + NH3
-
-
-
-
?
Glu-2-naphthylamide
?
-
-
-
-
?
glucagon(3-29)
?
-
-
-
-
?
glutamine tert-butyl ester
pyroglutamyl-tert-butyl ester + NH3
-
-
-
-
?
gonadotropin releasing hormone
?
-
-
-
-
?
H-Gln-7-amido-4-methylcoumarin
5-oxoprolyl-7-amido-4-methylcoumarin + NH3
H-Gln-7-amido-4-methylcoumarin
? + NH3
H-Gln-Ala-OH
5-oxoprolyl-Ala-OH + NH3
H-Gln-Asp-Glu-Leu-NH2
5-oxoprolyl-Asp-Glu-Leu-NH2 + NH3
H-Gln-beta-naphthylamide
5-oxoprolyl-beta-naphthylamide + NH3
H-Gln-Glu-Ala-Phe-NH2
5-oxoprolyl-Glu-Ala-Phe-NH2 + NH3
H-Gln-Glu-OH
5-oxoprolyl-Glu-OH + NH3
H-Gln-Glu-Tyr-Ala-NH2
5-oxoprolyl-Glu-Tyr-Ala-NH2 + NH3
-
-
-
?
H-Gln-Glu-Tyr-Phe-NH2
5-oxoprolyl-Glu-Tyr-Phe-NH2 + NH3
H-Gln-Gly-Pro-OH
5-oxoprolyl-Gly-Pro-OH + NH3
H-Gln-Lys-Arg-Leu-NH2
5-oxoprolyl-Lys-Arg-Leu-NH2 + NH3
H-Gln-Phe-Ala-NH2
5-oxoprolyl-Phe-Ala-NH2 + NH3
H-Gln-Phe-Ala-OH
5-oxoprolyl-Phe-Ala-OH + NH3
H-Gln-Phe-Arg-His-NH2
5-oxoprolyl-Phe-Arg-His-NH2 + NH3
-
-
-
-
?
H-Gln-Ser-Tyr-Phe-NH2
5-oxoprolyl-Ser-Tyr-Phe-NH2 + NH3
-
-
-
?
H-Gln-Tyr-Ala-OH
5-oxoprolyl-Tyr-Ala-OH + NH3
H-Gln-Val-Ala-OH
5-oxoprolyl-Val-Ala-OH + NH3
L-gamma-glutamyl-(+)-3-aminobutyric acid
?
-
-
-
-
?
L-gamma-glutamyl-(+)-3-aminoisobutyric acid
?
-
-
-
-
?
L-gamma-glutamyl-beta-alanine
?
-
-
-
-
?
L-gamma-glutamyl-ethylamine
?
-
-
-
-
?
L-gamma-glutamyl-methylamine
?
-
-
-
-
?
L-gamma-glutamyl-n-butylamine
?
-
-
-
-
?
L-gamma-glutamyl-n-propylamine
?
-
-
-
-
?
L-gamma-glutamyl-tert-butylamine
?
-
-
-
-
?
L-gamma-glutamylaniline
?
-
-
-
-
?
L-gamma-glutamylbenzylamine
?
-
-
-
-
?
L-gamma-glutamylcyclopentylamine
?
-
-
-
-
?
L-gamma-glutamylglycine
?
-
poor substrate
-
-
?
L-gamma-glutamylneohexylamine
?
-
-
-
-
?
L-gamma-glutamylneopentylamine
?
-
-
-
-
?
L-Gln(3)-amyloid-beta peptide 3-42
L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + NH3
L-Gln-2-naphthylamide
5-oxoprolyl-2-naphthylamide + NH3
L-Gln-2-naphthylamide
L-pyroglutamyl-2-naphthylamide + NH3
L-Gln-7-amido-4-methylcoumarin
5-oxoprolyl-4-methylcoumarin-7-amide + NH3
L-Gln-7-amido-4-methylcoumarin
5-oxoprolyl-7-amido-4-methylcoumarin + NH3
L-Gln-7-amido-4-methylcoumarin
L-pyroglutamyl-4-methylcoumarin-7-amide + NH3
L-Gln-7-amido-4-methylcoumarin
pyroglutamate-7-amido-4-methylcoumarin + NH3
-
-
-
-
?
L-Gln-amide
5-oxoprolyl-amide + NH3
L-Gln-Gly
5-oxoprolyl-Gly + NH3
L-Gln-Gly
5-oxoprolylglycine + NH3
L-Gln-Gly
L-pyroglutamyl-Gly + NH3
L-Gln-Gly-L-Pro
5-oxoprolyl-Gly-L-Pro + NH3
L-Gln-Gly-L-Pro
pyroglutamyl-Gly-L-Pro + NH3
L-Gln-L-Ala
L-pyroglutamyl-L-Ala + NH3
L-Gln-L-Arg-Gly-L-Ile-NH2
pyroglutamyl-L-Arg-Gly-L-Ile-NH2 + NH3
-
-
-
?
L-Gln-L-Asn-Gly-L-Ile-NH2
L-pyroglutamyl-L-Asn-Gly-L-Ile-NH2 + NH3
-
-
-
?
L-Gln-L-Asp-L-Glu-L-Leu-NH2
pyroglutamyl-L-Asp-L-Glu-L-Leu-NH2 + NH3
L-Gln-L-Gln
5-oxoprolyl-L-Gln + NH3
L-Gln-L-Gln
L-pyroglutamyl-L-Gln + NH3
L-Gln-L-Gln-OH
5-oxoprolyl-L-Gln + NH3
-
-
-
?
L-Gln-L-Glu
5-oxoprolyl-L-Glu + NH3
L-Gln-L-Glu
L-pyroglutamyl-L-Glu + NH3
L-Gln-L-Glu-L-Ala-L-Phe-NH2
pyroglutamyl-L-Glu-L-Ala-L-Phe-NH2 + NH3
L-Gln-L-Glu-L-Asp-L-Leu-NH2
5-oxoprolyl-L-Glu-L-Asp-L-Leu-NH2 + NH3
L-Gln-L-Glu-L-Tyr-L-Ala-NH2
pyroglutamic acid-L-Glu-L-Tyr-L-Ala-NH2 + NH3
-
-
-
?
L-Gln-L-Glu-L-Tyr-L-Phe-NH2
pyroglutamyl-L-Glu-L-Tyr-L-Phe-NH2 + NH3
L-Gln-L-Glu-OH
5-oxoprolyl-L-Glu + NH3
-
-
-
?
L-Gln-L-Lys-L-Arg-L-Leu
5-oxoprolyl-L-Lys-L-Arg-L-Leu + NH3
-
-
-
?
L-Gln-L-Lys-L-Arg-L-Leu-NH2
5-oxoprolyl-L-Lys-L-Arg-L-Leu-NH2 + NH3
L-Gln-L-Lys-L-Arg-L-Leu-NH2
pyroglutamyl-L-Lys-L-Arg-L-Leu-NH2 + NH3
L-Gln-L-Phe-L-Ala
5-oxoprolyl-L-Phe-L-Ala + NH3
-
-
-
?
L-Gln-L-Phe-L-Ala-NH2
5-oxoprolyl-L-Phe-L-Ala-NH2 + NH3
L-Gln-L-Phe-L-Ala-NH2
L-pyroglutamyl-L-Phe-L-Ala-NH2 + NH3
L-Gln-L-Ser-L-Tyr-L-Phe-NH2
pyroglutamic acid-L-Ser-L-Tyr-L-Phe-NH2 + NH3
-
-
-
?
L-Gln-L-Thr-Gly-L-Ile-NH2
L-pyroglutamyl-L-Thr-Gly-L-Ile-NH2 + NH3
-
-
-
?
L-Gln-L-Thr-L-Ala
5-oxoprolyl-L-Thr-L-Ala + NH3
-
-
-
-
?
L-Gln-L-Trp-L-Ala-NH2
L-pyroglutamyl-L-Trp-L-Ala-NH2 + NH3
-
-
-
?
L-Gln-L-Val-L-Ala-NH2
L-pyroglutamyl-L-Val-L-Ala-NH2 + NH3
L-Gln-NH2
L-pyroglutamyl amide + NH3
L-Gln-tert-butyl ester
5-oxoprolyl-tert-butyl ester + NH3
L-Gln-tert-butyl ester
L-pyroglutamyl-tert-butyl ester + NH3
L-Glu(3)-amyloid-beta peptide 3-42
L-pyroglutamyl(3)-amyloid-beta peptide 3-42 + H2O
L-Glu-2-naphthylamide
5-oxo-L-prolinyl-2-naphthylamide + NH3
-
-
-
-
?
L-Glu-2-naphthylamide
5-oxo-L-prolyl-2-naphthylamide + NH3
L-glutamine tert-butyl ester
L-pyroglutamate tert-butyl ester + NH3
-
-
-
-
?
L-glutaminyl 2-naphthylamide
L-glutamine + 2-naphthylamine
-
-
-
?
L-glutaminyl-2-naphthylamide
L-5-oxoprolyl-2-naphthylamide + NH3
-
-
-
-
?
L-glutaminyl-4-methylcoumarinylamide
L-5-oxoprolyl-4-methylcoumarinylamide + NH3
-
-
-
-
?
L-glutaminyl-7-amido-4-methylcoumarin
L-pyroglutamyl-7-amido-4-methylcoumarin + NH3
L-glutaminyl-7-amido-4-methylcoumarin
pGlu-7-amido-4-methylcoumarin + NH3
L-glutaminyl-Abeta(3-42) peptide
5-oxoprolyl-Abeta(3-42) peptide + NH3
L-glutaminyl-Abeta3-40/42
5-oxoprolyl-Abeta3-40/42 + NH3
amyloid-beta peptide Abeta3-40/42
-
-
r
L-glutaminyl-Abeta3-40/42 peptide
5-oxoprolyl-Abeta3-40/42 peptide + NH3
amyloid-beta peptide Abeta3-40/42
-
-
?
L-glutaminyl-amyloid beta peptide
5-oxoprolyl-amyloid beta peptide + NH3
L-glutaminyl-beta-naphthylamide
pGlu-beta-naphthylamide + NH3
L-glutaminyl-CCL2
5-oxoprolyl-CCL2 + NH3
L-glutaminyl-CD47
5-oxoprolyl-CD47 + NH3
-
-
-
?
L-glutaminyl-monocyte chemoattractant protein 1
5-oxoprolyl-monocyte chemoattractant protein 1 + NH3
L-glutaminyl-monocyte chemoattractant protein 3
5-oxoprolyl-monocyte chemoattractant protein 3 + NH3
i.e. MCP-3 or CCL7
-
-
?
L-glutaminyl-peptide
5-oxoprolyl-peptide + NH3
L-glutaminyl-Phe-Ala
5-oxoprolyl-Phe-Ala + NH3
-
-
-
r
Nepsilon-(L-gamma-glutamyl)-D-lysine
?
-
-
-
-
?
Nepsilon-(L-gamma-glutamyl)-L-lysine
5-oxoprolyl-L-lysine + NH3
-
-
-
-
?
O-(n-butylcarbamyl)-L-serine
?
-
-
-
-
?
QAAE
5-oxoprolyl-AAE + NH3
QAAF
5-oxoprolyl-AAF + NH3
QAAR
5-oxoprolyl-AAR + NH3
-
-
-
?
QAEA
5-oxoprolyl-AEA + NH3
QAFA
5-oxoprolyl-AFA + NH3
QARA
5-oxoprolyl-ARA + NH3
QEAA
5-oxoprolyl-EAA + NH3
QFAA
5-oxoprolyl-FAA + NH3
QGGG
5-oxoprolyl-GGG + NH3
QRAA
5-oxoprolyl-RAA + NH3
S-(cyclohexylamine)-L-cysteine
?
-
-
-
-
?
S-(n-butylcarbamyl)-L-cysteine
?
-
-
-
-
?
S-(n-propylcarbamyl)-L-cysteine
?
-
-
-
-
?
thyrotropin-releasing hormone
?
-
-
-
-
?
[Gln1,Gly4]-thyrotropin releasing hormone
?
-
-
-
-
?
[Gln1]-fertilization promoting peptide
[pyroglutamyl]-fertilization promoting peptide + NH3
[Gln1]-gastrin
[pyroglutamyl]-gastrin + NH3
[Gln1]-gonadotropin releasing-hormone
[pyroglutamyl]-gonadotropin releasing-hormone + NH3
[Gln1]-neurotensin
[pyroglutamyl]-neurotensin + NH3
[Gln1]-thyrotropin releasing-hormone
[pyroglutamyl]-thyrotropin releasing-hormone + NH3
-
-
-
-
?
additional information
?
-
EFRH-NH2
pEFRH-NH2 + H2O
-
-
-
-
?
EFRH-NH2
pEFRH-NH2 + H2O
-
-
-
-
?
EFRH-NH2
pEFRH-NH2 + H2O
-
-
-
-
?
EFRH-NH2
pEFRH-NH2 + H2O
-
-
-
-
?
EFRHHDSGYE-NH2
pEFRHHDSGYE-NH2 + H2O
-
-
-
-
?
EFRHHDSGYE-NH2
pEFRHHDSGYE-NH2 + H2O
-
-
-
-
?
EFRHHDSGYE-NH2
pEFRHHDSGYE-NH2 + H2O
-
-
-
-
?
EFRHHDSGYE-NH2
pEFRHHDSGYE-NH2 + H2O
-
-
-
-
?
Gln-7-amido-4-methylcoumarin
2.3.2.5 glutaminyl-peptide cyclotransferase
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