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[E2 NEDD8-conjugating enzyme Ubc12]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme Ubc12]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine720
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine720
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 2]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 2]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 4]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 4]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin-1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin-1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
additional information
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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additional information
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ALF4 binds to the enzyme and inhibits the activity of SCFTIR1, an E3 ligase responsible for degradation of the Aux/IAA transcriptional repressors
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additional information
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Rbx1 is a subunit of the related SCF (Skp1-Cdc53/Cul1-F-box protein) and von Hippel-Lindau (VHL) tumor suppressor (elongin BC-Cul2-VHL) E3 ubiquitin ligase complexes, where it functions as a component of Cdc53/Rbx1 and Cul2/ Rbx1 modules that activate ubiquitination of target proteins by the E2 ubiquitin-conjugating enzymes Cdc34 and Ubc5
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additional information
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the NEDD8 conjugating enzyme UBE2M binds specifically to RBX1
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additional information
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conjugation of RBX1 to NEDD8 substantially stimulates the reaction, by nearly 2000fold, activating both substrate-priming and chain-elongation reactions. Presence of NEDD8 coordinates ubiquitin ligation assembly
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additional information
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Ubc12, a NEDD8-specific E2 conjugating enzyme, is a substrate for auto-neddylation. Protease SENP8/DEN1 counteracts Ubc12 autoneddylation, and aberrant neddylation of Ubc12 and other NEDD8 conjugation pathway components is observed in SENP8-deficient cells
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additional information
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the enzyme Hrt1 is a RING-type E3 for Rub1 ligation to Cdc53
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine720
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine720
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 2]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 2]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 4]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 4]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin-1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin-1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
additional information
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the enzyme Hrt1 is a RING-type E3 for Rub1 ligation to Cdc53
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 1]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 1]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin 3]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin 3]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin Cdc53]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin Cdc53]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine
[E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
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Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Adenocarcinoma
SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma.
Adenocarcinoma, Bronchiolo-Alveolar
SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma.
Adrenocortical Adenoma
Squamous cell carcinoma-related oncogene is highly expressed in developing, normal, and adenomatous adrenal tissue but not in aggressive adrenocortical carcinomas.
Adrenocortical Carcinoma
Squamous cell carcinoma-related oncogene is highly expressed in developing, normal, and adenomatous adrenal tissue but not in aggressive adrenocortical carcinomas.
Breast Neoplasms
Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells.
Carcinoma
3q26 Amplifications in Cervical Squamous Carcinomas.
Carcinoma
Association of ring box-1 protein overexpression with clinicopathologic prognostic parameters in prostate carcinoma.
Carcinoma
Coamplification and Cooperation: Toward Identifying Biologically Relevant Oncogenes.
Carcinoma
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Carcinoma
Immunohistochemical Expression of DCUN1D1 in Non-small Cell Lung Carcinoma: Its Relation to Brain Metastasis.
Carcinoma
MicroRNA-195 inhibits growth and invasion of laryngeal carcinoma cells by directly targeting DCUN1D1.
Carcinoma
SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2.
Carcinoma
Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A.
Carcinoma
The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.
Carcinoma, Non-Small-Cell Lung
Immunohistochemical Expression of DCUN1D1 in Non-small Cell Lung Carcinoma: Its Relation to Brain Metastasis.
Carcinoma, Renal Cell
An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.
Carcinoma, Squamous Cell
Coamplification and Cooperation: Toward Identifying Biologically Relevant Oncogenes.
Carcinoma, Squamous Cell
Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A.
Carcinoma, Squamous Cell
The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.
Colorectal Neoplasms
MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting DCUN1D1.
Frontotemporal Lobar Degeneration
DCUN1D1 is a risk factor for frontotemporal lobar degeneration.
Glioma
SCCRO promotes glioma formation and malignant progression in mice.
Infertility
Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization.
Lung Neoplasms
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Lung Neoplasms
Evidence for frequent concurrent DCUN1D1, FGFR1, BCL9 gene copy number amplification in squamous cell lung cancer.
Lymphatic Metastasis
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Melanoma
The Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer.
Neoplasm Metastasis
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Neoplasm Metastasis
Immunohistochemical Expression of DCUN1D1 in Non-small Cell Lung Carcinoma: Its Relation to Brain Metastasis.
Neoplasm Metastasis
MicroRNA-302 inhibits cell migration and invasion in cervical cancer by targeting DCUN1D1.
Neoplasm Metastasis
SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2.
Neoplasm Metastasis
The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue.
Neoplasms
3q26 Amplifications in Cervical Squamous Carcinomas.
Neoplasms
Association of ring box-1 protein overexpression with clinicopathologic prognostic parameters in prostate carcinoma.
Neoplasms
Clinical significance of SCCRO (DCUN1D1) in prostate cancer and its proliferation-inhibiting effect on Lncap cells.
Neoplasms
Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function.
Neoplasms
DCUN1D1 facilitates tumor metastasis by activating FAK signaling and up-regulates PD-L1 in non-small-cell lung cancer.
Neoplasms
DCUN1D1 promotes tumour progress in prostate cancer and its effect on DU145 in vitro.
Neoplasms
Evidence for frequent concurrent DCUN1D1, FGFR1, BCL9 gene copy number amplification in squamous cell lung cancer.
Neoplasms
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Neoplasms
Expression of Ring Box-1 protein and its relationship with Fuhrman grade and other clinical-pathological parameters in renal cell cancer.
Neoplasms
Identification of druggable cancer driver genes amplified across TCGA datasets.
Neoplasms
Immunohistochemical Expression of DCUN1D1 in Non-small Cell Lung Carcinoma: Its Relation to Brain Metastasis.
Neoplasms
MicroRNA-195 inhibits growth and invasion of laryngeal carcinoma cells by directly targeting DCUN1D1.
Neoplasms
MicroRNA-520b Functions as a Tumor Suppressor in Colorectal Cancer by Inhibiting DCUN1D1.
Neoplasms
Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2.
Neoplasms
SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2.
Neoplasms
SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma.
Neoplasms
SCCRO promotes glioma formation and malignant progression in mice.
Neoplasms
SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1).
Neoplasms
Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A.
Neoplasms
Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas.
Neoplasms
Squamous cell carcinoma-related oncogene is highly expressed in developing, normal, and adenomatous adrenal tissue but not in aggressive adrenocortical carcinomas.
Neoplasms
The relation between Ring Box-1 protein overexpression and tumor grade and stage in bladder urothelial cell carcinoma.
Neoplasms
The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue.
Neoplasms
The Roles of Cullin-2 E3 Ubiquitin Ligase Complex in Cancer.
Neoplasms
The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.
Neoplasms
The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
Papilloma
MicroRNA?195 inhibits cell proliferation, migration and invasion by targeting defective in cullin neddylation 1 domain containing 1 in cervical cancer.
Prostatic Intraepithelial Neoplasia
Association of ring box-1 protein overexpression with clinicopathologic prognostic parameters in prostate carcinoma.
Prostatic Neoplasms
Clinical significance of SCCRO (DCUN1D1) in prostate cancer and its proliferation-inhibiting effect on Lncap cells.
Prostatic Neoplasms
DCUN1D1 promotes tumour progress in prostate cancer and its effect on DU145 in vitro.
Squamous Cell Carcinoma of Head and Neck
Expression of DCUN1D1 in laryngeal squamous cell carcinoma and its inhibiting effect on TU-177 cells after interfered by RNA.
Squamous Cell Carcinoma of Head and Neck
The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue.
Squamous Cell Carcinoma of Head and Neck
The ubiquitin-associated (UBA) domain of SCCRO/DCUN1D1 protein serves as a feedback regulator of biochemical and oncogenic activity.
Uterine Cervical Neoplasms
MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer.
Uterine Cervical Neoplasms
MicroRNA-302 inhibits cell migration and invasion in cervical cancer by targeting DCUN1D1.
Uterine Cervical Neoplasms
MicroRNA?195 inhibits cell proliferation, migration and invasion by targeting defective in cullin neddylation 1 domain containing 1 in cervical cancer.
von Hippel-Lindau Disease
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
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Onel, M.; Sumbul, F.; Liu, J.; Nussinov, R.; Haliloglu, T.
Cullin neddylation may allosterically tune polyubiquitin chain length and topology
Biochem. J.
474
781-795
2017
Homo sapiens (P62877)
brenda
Duda, D.; Borg, L.; Scott, D.; Hunt, H.; Hammel, M.; Schulman, B.
Structural insights into NEDD8 activation of Cullin-RING ligases conformational control of conjugation
Cell
134
995-1006
2008
Homo sapiens
brenda
Scott, D.; Sviderskiy, V.; Monda, J.; Lydeard, J.; Cho, S.; Harper, J.; Schulman, B.
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8
Cell
157
1671-1684
2014
Homo sapiens
brenda
Dharmasiri, S.; Dharmasiri, N.; Hellmann, H.; Estelle, M.
The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis
EMBO J.
22
1762-1770
2003
Arabidopsis thaliana
brenda
Bagchi, R.; Melnyk, C.; Christ, G.; Winkler, M.; Kirchsteiner, K.; Salehin, M.; Mergner, J.; Niemeyer, M.; Schwechheimer, C.; Caldern Villalobos, L.; Estelle, M.
The Arabidopsis ALF4 protein is a regulator of SCF E3 ligases
EMBO J.
37
255-268
2018
Arabidopsis thaliana
brenda
Megumi, Y.; Miyauchi, Y.; Sakurai, H.; Nobeyama, H.; Lorick, K.; Nakamura, E.; Chiba, T.; Tanaka, K.; Weissman, A.; Kirisako, T.; Ogawa, O.; Iwai, K.
Multiple roles of Rbx1 in the VBC-Cul2 ubiquitin ligase complex
Genes Cells
10
679-691
2005
Homo sapiens
brenda
Kamura, T.; Conrad, M.; Yan, Q.; Conaway, R.; Conaway, J.
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
Genes Dev.
13
2928-2933
1999
Homo sapiens
brenda
Kim, A.; Bommelje, C.; Lee, B.; Yonekawa, Y.; Choi, L.; Morris, L.; Huang, G.; Kaufman, A.; Ryan, R.; Hao, B.; Ramanathan, Y.; Singh, B.
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation
J. Biol. Chem.
283
33211-33220
2008
Mus musculus
-
brenda
Huang, G.; Kaufman, A.; Ramanathan, Y.; Singh, B.
SCCRO (DCUN1D1) promotes nuclear translocation and assembly of the neddylation E3 complex
J. Biol. Chem.
286
10297-10304
2011
Homo sapiens
brenda
Kurz, T.; Chou, Y.; Willems, A.; Meyer-Schaller, N.; Hecht, M.; Tyers, M.; Peter, M.; Sicheri, F.
Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation
Mol. Cell.
29
23-35
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