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Information on EC 2.3.2.21 - cyclo(L-tyrosyl-L-tyrosyl) synthase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.21 cyclo(L-tyrosyl-L-tyrosyl) synthase
IUBMB Comments
The reaction proceeds following a ping-pong mechanism forming a covalent intermediate between an active site serine and the first L-tyrosine residue . The protein, from the bacterium Mycobacterium tuberculosis, also forms small amounts of cyclo(L-tyrosyl-L-phenylalanyl) .
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The enzyme appears in viruses and cellular organisms
Synonyms
CDPS, CDPS-Np, cyclo(L-tyrosyl-L-tyrosyl) synthase, cyclodipeptide synthase, cyclodityrosine synthetase, cYY synthase, Rv2275, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2 L-tyrosyl-tRNATyr = 2 tRNATyr + cyclo(L-tyrosyl-L-tyrosyl)
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PATHWAY SOURCE
PATHWAYS
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