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The enzyme attaches the side chain of the aminoglycoside antibiotics of the butirosin family. The side chain confers resistance against several aminoglycoside-modifying enzymes.
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The expected taxonomic range for this enzyme is: Bacillus circulans
acp:aminoglycoside acyltransferase, more
4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] + ribostamycin = gamma-L-glutamyl-butirosin B + BtrI acyl-carrier protein
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