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Information on EC 2.3.2.15 - glutathione gamma-glutamylcysteinyltransferase and Organism(s) Lotus japonicus and UniProt Accession Q2QKL5

for references in articles please use BRENDA:EC2.3.2.15
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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.15 glutathione gamma-glutamylcysteinyltransferase
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This record set is specific for:
Lotus japonicus
UNIPROT: Q2QKL5 not found.
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Word Map
The taxonomic range for the selected organisms is: Lotus japonicus
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
nspcs, cepcs, phytochelatin synthase, atpcs1, ospcs1, ospcs2, atpcs2, atpcs, phytochelatin synthase 1, ljpcs1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
phytochelatin synthase
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gamma-glutamylcysteine dipeptidyl transpeptidase
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-
-
-
phytochelatin synthase
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
gamma-glutamylcysteinyl transfer
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-
-
-
PATHWAY SOURCE
PATHWAYS
-
-
SYSTEMATIC NAME
IUBMB Comments
glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
125390-02-5
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
glutathione + [Glu(-Cys)]n-Gly
Gly + [Glu(-Cys)]n+1-Gly
show the reaction diagram
-
-
-
-
?
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Al3+
activation of LjPCS3
Cu2+
activation of LjPCS3
Fe2+
activation of LjPCS3
Hg2+
activation of LjPCS3
KH2AsO4
activation of LjPCS3
Pb2+
activation of LjPCS3
Zn2+
activation of LjPCS3
Al3+
activation of LjPCS1
Fe2+
activation of LjPCS1
Pb2+
best activator of LjPCS1 in the in vitro assay
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
SwissProt
Manually annotated by BRENDA team
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
PCS3_LOTJA
479
0
53187
Swiss-Prot
other Location (Reliability: 4)
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Saccharomyces cerevisiae. Yeast cells expressing LjPCS3 show increased in vivo tolerance to Cd
expressed in Saccharomyces cerevisiae
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expression in Saccharomyces cerevisiae
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Ramos, J.; Clemente, M.R.; Naya, L.; Loscos, J.; Perez-Rontome, C.; Sato, S.; Tabata, S.; Becana, M.
Phytochelatin synthases of the model legume Lotus japonicus. A small multigene family with differential response to cadmium and alternatively spliced variants
Plant Physiol.
143
1110-1118
2007
Lotus japonicus
Manually annotated by BRENDA team
Ramos, J.; Naya, L.; Gay, M.; Abian, J.; Becana, M.
Functional characterization of an unusual phytochelatin synthase, LjPCS3, of Lotus japonicus
Plant Physiol.
148
536-545
2008
Lotus japonicus (Q2QKL5), Lotus japonicus (Q2TSC7), Lotus japonicus
Manually annotated by BRENDA team