Information on EC 2.3.2.1 - D-glutamyltransferase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.1 D-glutamyltransferase
IUBMB Comments
The enzyme catalyses two reactions. The first is the transfer of a glutamyl residue from L- or D-glutamine to D-glutamate via a gamma linkage, forming gamma-glutamyl-D-glutamate, and the second is the transfer of additional glutamyl residues to the peptide, extending the polypeptide chain.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
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D-glutamine
+
D-glutamate
=
NH3
+
gamma-D-glutamyl-D-glutamate
+
=
+
L(or D)-glutamine
+
(gamma-D-glutamyl)n-[peptide]
=
NH3
+
(gamma-D-glutamyl)n+1-[peptide]
+
(gamma-D-glutamyl)n-[peptide]
=
+
(gamma-D-glutamyl)n+1-[peptide]
Synonyms
D-gamma-glutamyl transpeptidase, D-glutamyl transpeptidase, gamma-GT, glutamyltransferase, D-, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-glutamine + D-glutamate = NH3 + gamma-D-glutamyl-D-glutamate
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(1)
-
-
-
L(or D)-glutamine + (gamma-D-glutamyl)n-[peptide] = NH3 + (gamma-D-glutamyl)n+1-[peptide]
show the reaction diagram
(2)
-
-
-
PATHWAY SOURCE
PATHWAYS
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