Information on EC 2.3.1.9 - acetyl-CoA C-acetyltransferase

for references in articles please use BRENDA:EC2.3.1.9
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This record set is specific for:
UNIPROT: P07256


The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

EC NUMBER
COMMENTARY hide
2.3.1.9
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RECOMMENDED NAME
GeneOntology No.
acetyl-CoA C-acetyltransferase
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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condensation
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thiolytic cleavage
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
ethylmalonyl-CoA pathway
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acetoacetate degradation (to acetyl CoA)
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L-lysine fermentation to acetate and butanoate
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glutaryl-CoA degradation
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pyruvate fermentation to butanoate
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mevalonate pathway III (archaea)
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ketolysis
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acetyl-CoA fermentation to butanoate II
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crotonate fermentation (to acetate and cyclohexane carboxylate)
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pyruvate fermentation to butanol II (engineered)
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fermentation to 2-methylbutanoate
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ketogenesis
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(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)
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isoprene biosynthesis II (engineered)
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mevalonate pathway II (archaea)
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L-isoleucine degradation I
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isopropanol biosynthesis (engineered)
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2-methylpropene degradation
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methyl tert-butyl ether degradation
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L-glutamate degradation V (via hydroxyglutarate)
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polyhydroxybutanoate biosynthesis
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mevalonate pathway I
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pyruvate fermentation to hexanol (engineered)
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pyruvate fermentation to butanol I
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3-hydroxypropanoate/4-hydroxybutanate cycle
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pyruvate fermentation to acetone
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butanoate fermentation
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CO2 fixation in Crenarchaeota
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mevalonate metabolism
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tryptophan metabolism
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Fatty acid degradation
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Synthesis and degradation of ketone bodies
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Valine, leucine and isoleucine degradation
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Lysine degradation
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Benzoate degradation
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Tryptophan metabolism
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Pyruvate metabolism
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Glyoxylate and dicarboxylate metabolism
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Propanoate metabolism
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Butanoate metabolism
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Carbon fixation pathways in prokaryotes
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Terpenoid backbone biosynthesis
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Metabolic pathways
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Biosynthesis of secondary metabolites
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Microbial metabolism in diverse environments
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Biosynthesis of antibiotics
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SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:acetyl-CoA C-acetyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9027-46-7
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SwissProt
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
show the reaction diagram
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?, r
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
CoA + acetoacetyl-CoA
acetyl-CoA + acetyl-CoA
show the reaction diagram
P07256
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?
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40598
4 * 40598, deduced from nucleotide sequence
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
tetramer
4 * 40598, deduced from nucleotide sequence