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Information on EC 2.3.1.82 - aminoglycoside 6'-N-acetyltransferase

for references in articles please use BRENDA:EC2.3.1.82
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EC Tree
IUBMB Comments
The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C1a, gentamicin C2 and sisomicin are substrates. The antibiotic tobramycin, but not paromomycin, can also act as acceptor. The 6-amino group of the purpurosamine ring is acetylated.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
Synonyms
aac(6')-ib-cr, aac(6')-ib, aaca-aphd, aac(6'), aac(6')-i, aac(6')-ii, aminoglycoside 6'-n-acetyltransferase, aac(6')-im, aac(6')-ie, aac(6')-iy, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + kanamycin-B = CoA + N6'-acetylkanamycin-B
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Staphylococcus aureus
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