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Information on EC 2.3.1.68 - glutamine N-acyltransferase for references in articles please use BRENDA:EC2.3.1.68Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
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The enzyme appears in viruses and cellular organisms
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glutamine N-acyltransferase
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acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine
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Acyl group transfer
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acyl-CoA:L-glutamine N-acyltransferase
Phenylacetyl-CoA and (indol-3-yl)acetyl-CoA, but not benzoyl-CoA, can act as acyl donors. Not identical with EC 2.3.1.13 glycine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.
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indoleacetyl-CoA + L-glutamine
CoA + indoleacetyl-L-glutamine
phenylacetyl-CoA + L-glutamine
CoA + phenylacetyl-L-glutamine
indoleacetyl-CoA + L-glutamine
CoA + indoleacetyl-L-glutamine
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indoleacetyl-CoA + L-glutamine
CoA + indoleacetyl-L-glutamine
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phenylacetyl-CoA + L-glutamine
CoA + phenylacetyl-L-glutamine
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phenylacetyl-CoA + L-glutamine
CoA + phenylacetyl-L-glutamine
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benzoyl-CoA
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weak competitive
butyryl-CoA
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0.4 mM, in presence of 100 mM L-glutamine, 50% loss of activity
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0.035
phenylacetyl-CoA
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0.17
benzoyl-CoA
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with phenylacetyl-CoA as substrate
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GLYL1_HUMAN
302
35101
Swiss-Prot
GLYLB_HUMAN
302
34553
Swiss-Prot
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Webster, L.T.; Siddiqui, U.A.; Lucas, S.V.; Strong, J.M.; Mieyal, J.J.
Identification of separate acyl-CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man
J. Biol. Chem.
251
3352-3358
1976
Homo sapiens, Macaca mulatta
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