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Information on EC 2.3.1.48 - histone acetyltransferase
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2.3.1.48 histone acetyltransferaseIUBMB Comments
A group of enzymes acetylating histones. Several of the enzymes can also acetylate lysines in other proteins [3,4].
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Word Map
- 2.3.1.48
- rhythm
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oscillation
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suprachiasmatic
- chromatin
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entrain
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night
- scn
- sleep
- melatonin
- drosophila
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diurnal
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pacemaker
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locomotor
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light-dark
- nuclei
- deacetylases
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pineal
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morning
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photoperiodic
- retinal
-
draw
- hypothalamus
- hdacs
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light-induced
- melanogaster
- photoreceptors
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noise
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bayesian
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nocturnal
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evening
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daytime
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deacetylation
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coherent
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co-activator
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oscillatory
- dementia
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transactivation
- flies
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neuropeptide
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wake
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schedule
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24-hour
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pulses
-
circuit
- medicine
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lengthen
- molecular biology
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trichostatin
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mood
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verbal
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neuropsychological
- drug development
- tick
- analysis
- pharmacology
The enzyme appears in viruses and cellular organisms
Synonyms
clock, histone acetyltransferase, n-acetyltransferase, tip60, histone acetyltransferases, cbp/p300, creb-binding protein, ep300, crebbp, creb binding protein, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
acetyltransferase, histone
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histone acetokinase
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histone acetylase
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histone transacetylase
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nucleosome-histone acetyltransferase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Acyl group transfer
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SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:[protein]-L-lysine acetyltransferase
A group of enzymes acetylating histones. Several of the enzymes can also acetylate lysines in other proteins [3,4].
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CAS REGISTRY NUMBER
COMMENTARY
9054-51-7
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
-
additional information
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analysis of KATi, bisubstrate analogues, natural compounds and synthetic derivatives, mechanism of action, structure-activity relationships, and pharmacokinetic/pharmacodynamic properties, overview
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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Circadian clock gene plays a key role on ovarian cycle and spontaneous abortion.
Abortion, Spontaneous
Genetic variation in the CLOCK gene is associated with idiopathic recurrent spontaneous abortion.
Abortion, Spontaneous
Xenobiotic metabolism genes and the risk of recurrent spontaneous abortion.
Abscess
Innovative approach in the management of horse-shoe fistula-in-ano with K??ras?tra.
Accelerated Idioventricular Rhythm
A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-? Production.
Acidosis
Extracellular Acidosis Promotes Metastatic Potency via Decrease of the BMAL1 Circadian Clock Gene in Breast Cancer.
Acquired Immunodeficiency Syndrome
Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.
Acquired Immunodeficiency Syndrome
Clock expires on case of an inmate sickened by AIDS drugs.
Acquired Immunodeficiency Syndrome
Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.
Acquired Immunodeficiency Syndrome
Legal clock starts at realization of harm, not AIDS diagnosis.
Acquired Immunodeficiency Syndrome
Light and circadian regulation of clock components aids flexible responses to environmental signals.
Acquired Immunodeficiency Syndrome
Reliability and reproducibility of several methods of arthroscopic assessment of femoral tunnel position during anterior cruciate ligament reconstruction.
Acquired Immunodeficiency Syndrome
Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.
Acquired Immunodeficiency Syndrome
Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin ?(12)-PGJ(2) through Covalent Binding to Cys(1438).
Acquired Immunodeficiency Syndrome
The PAS/LOV protein VIVID controls temperature compensation of circadian clock phase and development in Neurospora crassa.
Acquired Immunodeficiency Syndrome
The pseudo-receiver domain of CikA regulates the cyanobacterial circadian input pathway.
Acquired Immunodeficiency Syndrome
Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain.
Acute Coronary Syndrome
Circadian locomotor output cycles kaput accelerates atherosclerotic plaque formation by upregulating plasminogen activator inhibitor-1 expression.
Acute Lung Injury
CLOCK modulates survival and acute lung injury in mice with polymicrobial sepsis.
Acute Lung Injury
Stabilization of the histone acetyltransferase Tip60 by deubiquitinating enzyme USP7 stimulates the release of pro-inflammatory mediators in acute lung injury.
Adenocarcinoma
A pilot study investigating the role of NAT1 and NAT2 polymorphisms in gastric adenocarcinoma.
Adenocarcinoma
Circadian gene expression and clinicopathologic correlates in pancreatic cancer.
Adenocarcinoma
Comprehensive analysis of histone modification-associated genes on differential gene expression and prognosis in gastric cancer.
Adenocarcinoma
Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A.
Adenocarcinoma
Expression pattern and prognostic value of circadian clock genes in pancreatic adenocarcinoma.
Adenocarcinoma
GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas.
Adenocarcinoma
Inherited polymorphism in the N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and susceptibility to gastric and colorectal adenocarcinoma.
Adenocarcinoma
KAT2A succinyltransferase activity-mediated 14-3-3? upregulation promotes ?-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells.
Adenocarcinoma
N-Acetyltransferase 2 (NAT2) genetic variation and the susceptibility to noncardiac gastric adenocarcinoma in Taiwan.
Adenocarcinoma
Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer.
Adenocarcinoma
The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.
Adenocarcinoma
The circadian clock is associated with prognosis and immune infiltration in stomach adenocarcinoma.
Adenocarcinoma
[The research the relationship between N-acetyltransferase 1 gene polymorphisms and genetic susceptibility to sporadic colorectal adenocarcinoma]
Adenocarcinoma of Lung
Circadian clock associates with tumor microenvironment in thoracic cancers.
Adenocarcinoma of Lung
Differences in Genomic Alterations Between Brain Metastases and Primary Tumors.
Adenocarcinoma of Lung
KAT2B is an immune infiltration-associated biomarker predicting prognosis and response to immunotherapy in non-small cell lung cancer.
Adenocarcinoma of Lung
Serum factor(s) from lung adenocarcinoma patients regulates the molecular clock expression.
Adenocarcinoma, Follicular
Circadian clock characteristics are altered in human thyroid malignant nodules.
Adenoma
Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
Adenoma
Analysis of Secondary Phenotype Involving the Interactive Effect of the Secondary Phenotype and Genetic Variants on the Primary Disease.
Adenoma
Case-control study of the PERIOD3 clock gene length polymorphism and colorectal adenoma formation.
Adenoma
Doneness preferences, meat and meat-derived heterocyclic amines intake, and N-acetyltransferase 2 polymorphisms: association with colorectal adenoma in Japanese Brazilians.
Adenoma
Identification of Differential Transcriptional Patterns in Primary and Secondary Hyperparathyroidism.
Adenoma
Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling.
Adenoma
Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk.
Adenoma
Melatonin Exerts Direct Inhibitory Actions on ACTH Responses in the Human Adrenal Gland.
Adenoma
N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.
Adenoma
The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock and Enhances Malignant Phenotypes.
Adenoma
Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas.
Adenoma
Whole-exome sequencing identified mutational profiles of high-grade colon adenomas.
Adenomatous Polyposis Coli
Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial adenomatous polyposis.
Adenomatous Polyposis Coli
E7386, a Selective Inhibitor of the Interaction between ?-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
Agnosia
[Acalculia with clock agnosia in a patient with right cerebral hemisphere lesion and hidden lefthandedness]
Agranulocytosis
Dapsone-induced agranulocytosis - possible involvement of low activity N-acetyltransferase 2.
AIDS Dementia Complex
Epilepsy-associated neurocognitive disorders (EAND) in an onchocerciasis-endemic rural community in Cameroon: A population-based case-control study.
Alagille Syndrome
The vertebrate segmentation clock and its role in skeletal birth defects.
Allesthesia
On the different mechanisms of spatial transpositions: a case of representational allochiria in clock drawing.
Allesthesia
Spatial transpositions across tasks and response modalities: exploring representational allochiria.
Alzheimer Disease
A 7 minute neurocognitive screening battery highly sensitive to Alzheimer's disease.
Alzheimer Disease
A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment.
Alzheimer Disease
A decrease in N-acetylaspartate and an increase in myoinositol in the anterior cingulate gyrus are associated with behavioral and psychological symptoms in Alzheimer's disease.
Alzheimer Disease
A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression(1,2,3).
Alzheimer Disease
A simple scoring system for clock drawing in patients with Alzheimer's disease.
Alzheimer Disease
A?-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer's disease.
Alzheimer Disease
Actigraphy for Assessing Light Effects on Sleep and Circadian Activity Rhythm in Alzheimer's Dementia: A Narrative Review.
Alzheimer Disease
Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease.
Alzheimer Disease
Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer's Disease.
Alzheimer Disease
Amyloid-?-Induced Changes in Molecular Clock Properties and Cellular Bioenergetics.
Alzheimer Disease
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
Alzheimer Disease
APOE-epsilon4 polymorphism and cognitive deficit among the elderly population of Fernando de Noronha.
Alzheimer Disease
Attempt to Predict A/T/N-Based Alzheimer's Disease Cerebrospinal Fluid Biomarkers Using a Peripheral Blood DNA Methylation Clock.
Alzheimer Disease
Brain structural and cognitive correlates of clock drawing performance in Alzheimer's disease.
Alzheimer Disease
Broad spectrum assessment of psychopathology and adaptive functioning with the Older Adult Behavior Checklist: a validation and diagnostic discrimination study.
Alzheimer Disease
Can clock drawing differentiate Alzheimer's disease from other dementias?
Alzheimer Disease
Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease.
Alzheimer Disease
Central and peripheral circadian clocks and their role in Alzheimer's disease.
Alzheimer Disease
Changes in cortical activation during retrieval of clock time representations in patients with mild cognitive impairment and early Alzheimer's disease.
Alzheimer Disease
Changes over time in memory, processing speed and clock drawing tests help to discriminate between vascular cognitive impairment, mild cognitive impairment and Alzheimer's disease.
Alzheimer Disease
Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
Alzheimer Disease
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain.
Alzheimer Disease
Circadian Clock Gene Expression in Brain Regions of Alzheimer 's Disease Patients and Control Subjects.
Alzheimer Disease
Circadian clock gene polymorphisms and sleep--wake disturbance in Alzheimer disease.
Alzheimer Disease
Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test.
Alzheimer Disease
Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1.
Alzheimer Disease
Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment.
Alzheimer Disease
Clock drawing and frontal lobe behavioral effects of memantine in Alzheimer's disease: a rater-blinded study.
Alzheimer Disease
Clock drawing errors in dementia: neuropsychological and neuroanatomical considerations.
Alzheimer Disease
Clock drawing in Alzheimer's disease. A novel measure of dementia severity.
Alzheimer Disease
Clock drawing performance and brain morphology in mild cognitive impairment and Alzheimer's disease.
Alzheimer Disease
Clock drawing test in institutionalized patients with schizophrenia compared with Alzheimer's disease patients.
Alzheimer Disease
Clock drawing test ratings by dementia specialists: interrater reliability and diagnostic accuracy.
Alzheimer Disease
Clock Test Deficits Are Associated With Semantic Memory Impairment in Alzheimer Disease.
Alzheimer Disease
Clocking delirium: the value of the Clock Drawing Test with case illustrations.
Alzheimer Disease
Cognitive effects of a dietary supplement made from extract of Bacopa monnieri, astaxanthin, phosphatidylserine, and vitamin E in subjects with mild cognitive impairment: a noncomparative, exploratory clinical study.
Alzheimer Disease
Cognitive function in UK community-dwelling African Caribbean elders: normative data for a test battery.
Alzheimer Disease
Cognitive Impairment and Dementia: Gaining Insight through Circadian Clock Gene Pathways.
Alzheimer Disease
Combining cognitive screening tests for the evaluation of mild cognitive impairment in the elderly.
Alzheimer Disease
Comparing clock tests for dementia screening: naïve judgments vs formal systems--what is optimal?
Alzheimer Disease
Comparison of a clock drawing test in elderly schizophrenia and Alzheimer's disease patients: a preliminary study.
Alzheimer Disease
Comparisons of cognitive function and serum S-100B level between diabetic and non-diabetic patients after the implantation of carotid artery stent (CAS).
Alzheimer Disease
Cortical signature of clock drawing performance in Alzheimer's disease and mild cognitive impairment.
Alzheimer Disease
CREB-binding protein activation by presenilin 1 but not by its M146L mutant.
Alzheimer Disease
Decreased vasopressin gene expression in the biological clock of Alzheimer disease patients with and without depression.
Alzheimer Disease
Development of a Brief Cognitive Screen for Mild Cognitive Impairment and Neurocognitive Disorder.
Alzheimer Disease
Development of scoring criteria for the clock drawing task in Alzheimer's disease.
Alzheimer Disease
Diagnostic performance of a combination of Mini-Mental State Examination and Clock Drawing Test in detecting Alzheimer's disease.
Alzheimer Disease
Diagnostic Performance of Clock Drawing Test by CLOX in an Asian Chinese population.
Alzheimer Disease
Diagnostic value of digital clock drawing test in comparison with CERAD neuropsychological battery total score for discrimination of patients in the early course of Alzheimer's disease from healthy individuals.
Alzheimer Disease
Discrimination of dementia with lewy bodies from Alzheimer disease and Parkinson disease using the clock drawing test.
Alzheimer Disease
Discriminative capacity and construct validity of the Clock Drawing Test in Mild Cognitive Impairment and Alzheimer's disease.
Alzheimer Disease
Disruption of Bmal1 impairs blood-brain barrier integrity via pericyte dysfunction.
Alzheimer Disease
Does the Combination of the MMSE and Clock Drawing Test (Mini-Clock) Improve the Detection of Mild Alzheimer's Disease and Mild Cognitive Impairment?
Alzheimer Disease
Drosophila Eye Model to Study Neuroprotective Role of CREB Binding Protein (CBP) in Alzheimer's Disease.
Alzheimer Disease
Early Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer's Disease.
Alzheimer Disease
Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease.
Alzheimer Disease
Effects of Intermittent Theta Burst Stimulation on the Clock Drawing Test Performances in Patients with Alzheimer's Disease.
Alzheimer Disease
Effects of the Clock Modulator Nobiletin on Circadian Rhythms and Pathophysiology in Female Mice of an Alzheimer's Disease Model.
Alzheimer Disease
Efficacy and safety of galantamine (reminyl) for dementia in patients with Parkinson's disease (an open controlled trial).
Alzheimer Disease
Elevated CLOCK and BMAL1 Contribute to the Impairment of Aerobic Glycolysis from Astrocytes in Alzheimer's Disease.
Alzheimer Disease
Epigenetic Regulation of Axonal Growth of Drosophila Pacemaker Cells by Histone Acetyltransferase Tip60 Controls Sleep.
Alzheimer Disease
Executive Abilities as Reflected by Clock Hand Placement: Frontotemporal Dementia Versus Early-Onset Alzheimer Disease.
Alzheimer Disease
Exploring the multifunctional role of melatonin in regulating autophagy and sleep to mitigate Alzheimer's disease neuropathology.
Alzheimer Disease
Functional CLOCK gene rs1554483 G/C polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese population.
Alzheimer Disease
Functional neuroanatomical correlates of the executive clock drawing task (CLOX) performance in Alzheimer's disease: a FDG-PET study.
Alzheimer Disease
Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer's disease.
Alzheimer Disease
Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease.
Alzheimer Disease
Improvement pattern in the clock drawing test in early Alzheimer's disease.
Alzheimer Disease
Increased Diagnostic Accuracy of Digital vs. Conventional Clock Drawing Test for Discrimination of Patients in the Early Course of Alzheimer's Disease from Cognitively Healthy Individuals.
Alzheimer Disease
Increasing Tip60 HAT levels rescues axonal transport defects and associated behavioral phenotypes in a Drosophila Alzheimer's disease model.
Alzheimer Disease
Influence of ApoE Genotype and Clock T3111C Interaction with Cardiovascular Risk Factors on the Progression to Alzheimer's Disease in Subjective Cognitive Decline and Mild Cognitive Impairment Patients.
Alzheimer Disease
Inhibition of casein kinase 1?/?improves cognitive-affective behavior and reduces amyloid load in the APP-PS1 mouse model of Alzheimer's disease.
Alzheimer Disease
Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects.
Alzheimer Disease
Intra-individual variability in Alzheimer's disease and cognitive aging: definitions, context, and effect sizes.
Alzheimer Disease
Lack of association between genetic polymorphism of circadian genes (PER2, PER3, CLOCK and OX2R) with late onset depression and Alzheimer's disease in a sample of a Brazilian population (Circadian Genes, Late-Onset Depression and Alzheimer's Disease).
Alzheimer Disease
Learning Classification Models of Cognitive Conditions from Subtle Behaviors in the Digital Clock Drawing Test.
Alzheimer Disease
Machine Learning Analysis of Digital Clock Drawing Test Performance for Differential Classification of Mild Cognitive Impairment Subtypes Versus Alzheimer's Disease.
Alzheimer Disease
MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration.
Alzheimer Disease
MARIO Project: Validation and Evidence of Service Robots for Older People with Dementia.
Alzheimer Disease
Metabolic alterations associated with impaired clock drawing in Lewy body dementia.
Alzheimer Disease
Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response.
Alzheimer Disease
Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases.
Alzheimer Disease
Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.
Alzheimer Disease
N-acetyltransferase (NAT2) genotype and susceptibility of sporadic Alzheimer's disease.
Alzheimer Disease
N-Acetyltransferase 2 gene polymorphism in a group of senile dementia patients in Shanghai suburb.
Alzheimer Disease
Neural correlates of impaired performance on the clock drawing test in Alzheimer's disease.
Alzheimer Disease
Neural Correlates of the Clock Drawing Test Performance in Alzheimer's Disease: A FDG-PET Study.
Alzheimer Disease
Neuroanatomical correlates of error types on the Clock Drawing Test in Alzheimer's disease patients.
Alzheimer Disease
New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation.
Alzheimer Disease
Normative References for Graphomotor and Latency Digital Clock Drawing Metrics for Adults Age 55 and Older: Operationalizing the Production of a Normal Appearing Clock.
Alzheimer Disease
Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study.
Alzheimer Disease
Performance on the clock drawing task correlates with FMRI response to a visuospatial task in Alzheimer's disease.
Alzheimer Disease
Physical Exercise with Multicomponent Cognitive Intervention for Older Adults with Alzheimer's Disease: A 6-Month Randomized Controlled Trial.
Alzheimer Disease
Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock".
Alzheimer Disease
Platelet a disintegrin and metallopeptidase 10 expression correlates with clock drawing test scores in Alzheimer's disease.
Alzheimer Disease
Polymorphism of CLOCK Gene rs 4580704 C>G Is Associated with Susceptibility of Alzheimer's Disease in a Chinese Population.
Alzheimer Disease
Postmortem tracing reveals the organization of hypothalamic projections of the suprachiasmatic nucleus in the human brain.
Alzheimer Disease
Qualitative analyses of clock drawings in Alzheimer's disease and vascular dementia.
Alzheimer Disease
Qualitative Features of Clock Drawings in Normal Aging and Alzheimer's Disease
Alzheimer Disease
Quantitative and qualitative analyses of clock drawing in frontotemporal dementia and Alzheimer's disease.
Alzheimer Disease
Quantitative and Qualitative Analyses of the Clock Drawing Test in Fall and Non-Fall Patients with Alzheimer's Disease.
Alzheimer Disease
Quantitative and qualitative analyses of the clock drawing test in mild cognitive impairment and Alzheimer disease: evaluation of a modified scoring system.
Alzheimer Disease
Real-world navigation in amnestic mild cognitive impairment: The relation to visuospatial memory and volume of hippocampal subregions.
Alzheimer Disease
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
Alzheimer Disease
Relationship between clock drawing test performance and regional cerebral blood flow in Alzheimer's disease: a single photon emission computed tomography study.
Alzheimer Disease
Relationships Between Behavioral Syndromes and Cognitive Domains in Alzheimer Disease: The Impact of Mood and Psychosis.
Alzheimer Disease
Relationships Between Cognition and Neuropathological Tau in Alzheimer's Disease Assessed by 18F Flortaucipir PET.
Alzheimer Disease
Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition.
Alzheimer Disease
Rivastigmine tartrate with a focus on dementia associated with Parkinson's disease.
Alzheimer Disease
Screening for Alzheimer's Disease Among Illiterate Elderly: Accuracy Analysis for Multiple Instruments.
Alzheimer Disease
Strong Circadian Rhythms in the Choroid Plexus: Implications for Sleep-Independent Brain Metabolite Clearance.
Alzheimer Disease
Ten-point clock test sensitivity for Alzheimer's disease in patients with MMSE scores greater than 23.
Alzheimer Disease
Ten-Point Clock test: a correlation analysis with mini-mental state and proverb interpretation score in Alzheimer's disease.
Alzheimer Disease
The abbreviated form of the Brief Cognitive Battery in the diagnosis of dementia in Alzheimer's disease.
Alzheimer Disease
The accuracy of the Clock Drawing Test compared to that of standard screening tests for Alzheimer's disease: results from a study of Brazilian elderly with heterogeneous educational backgrounds.
Alzheimer Disease
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
Alzheimer Disease
The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease.
Alzheimer Disease
The Clock Test: a sensitive measure to differentiate normal elderly from those with Alzheimer disease.
Alzheimer Disease
The Effectiveness of Reality Orientation in the Treatment of Alzheimer's Disease.
Alzheimer Disease
The Effectiveness of Reality Orientation Therapy in the Treatment of Parkinson Disease Dementia.
Alzheimer Disease
The four-point scoring system for the clock drawing test does not differentiate between Alzheimer's disease and vascular dementia.
Alzheimer Disease
The interlocking finger test in patients with Parkinson's disease and healthy subjects.
Alzheimer Disease
The minute hand phenomenon in the clock test of patients with early Alzheimer disease.
Alzheimer Disease
The Polymorphism of CLOCK Gene 3111T/C C>T Is Associated With Susceptibility of Alzheimer Disease in Chinese Population.
Alzheimer Disease
The relevance of hippocampal subfield integrity and clock drawing test performance for the diagnosis of Alzheimer's disease and mild cognitive impairment.
Alzheimer Disease
The reversed clock drawing test phenomenon in Alzheimer's disease: A perfusion SPECT study.
Alzheimer Disease
The Rhythmicity of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer's Disease.
Alzheimer Disease
The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia.
Alzheimer Disease
The short cognitive evaluation battery in cognitive disorders of the elderly--Italian version.
Alzheimer Disease
The six-item Clock Drawing Test - reliability and validity in mild Alzheimer's disease.
Alzheimer Disease
The Stick Design Test on the assessment of older adults with low formal education: evidences of construct, criterion-related and ecological validity.
Alzheimer Disease
The use of neuropsychological tests across Europe: the need for a consensus in the use of assessment tools for dementia.
Alzheimer Disease
The use of the Clock Drawing Test in bipolar disorder with or without dementia of Alzheimer's type.
Alzheimer Disease
The validation of a mailed health survey for screening of dementia of the Alzheimer's type.
Alzheimer Disease
Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60.
Alzheimer Disease
Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model.
Alzheimer Disease
Tracking cognitive functioning over time: ten-year longitudinal data from a community-based study.
Alzheimer Disease
Trajectories and risk factors of dementia progression: a memory clinic cohort followed up to 3 years from diagnosis.
Alzheimer Disease
Use of the clock drawing task in the diagnosis of mild and very mild Alzheimer's disease.
Alzheimer Disease
Use of the ten-point clock test to compare executive functioning across 24 months in patients with subcortical vascular dementia.
Alzheimer Disease
Validity and Clinical Utility of Different Clock Drawing Test Scoring Systems in Multiple Forms of Dementia.
Alzheimer Disease
Visual exploration behaviour during clock reading in Alzheimer's disease.
Alzheimer Disease
Western diet-induced obesity disrupts the diurnal rhythmicity of hippocampal core clock gene expression in a mouse model.
Alzheimer Disease
[A proposal for application and scoring of the Clock Drawing Test in Alzheimer's disease]
Alzheimer Disease
[Asymptomatic encephalic calcifications in postsurgical hypoparathyroidism.]
Alzheimer Disease
[Clock drawing in dementia: its reliability and relation to the neuropsychological measures]
Alzheimer Disease
[Effect of early acupuncture on cognitive function in patients with vascular dementia after cerebral infarction].
Alzheimer Disease
[Quantitative and qualitative analyses for characteristics of the clock drawing in Alzheimer's disease].
Alzheimer Disease
[Test scores as indicators of treatment efficacy in dementia caused by Alzheimer's disease in clinical practice].
Amnesia
The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.
Amyloidosis
Patient outcomes in light chain (AL) amyloidosis: The clock is ticking from symptoms to diagnosis.
Amyotrophic Lateral Sclerosis
Altered expression of clock and clock-controlled genes in a hSOD1-linked amyotrophic lateral sclerosis mouse model.
Amyotrophic Lateral Sclerosis
Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Amyotrophic Lateral Sclerosis
Racing against the clock: recognizing, differentiating, diagnosing, and referring the amyotrophic lateral sclerosis patient.
Anaphylaxis
Circadian clock gene Period2 regulates a time-of-day-dependent variation in cutaneous anaphylactic reaction.
Anaphylaxis
Disruption of the suprachiasmatic nucleus blunts a time of day-dependent variation in systemic anaphylactic reaction in mice.
Anemia, Aplastic
Epigenetic Aging and Hematopoietic Cell Transplantation in Patients With Severe Aplastic Anemia.
Anemia, Iron-Deficiency
[Polymorphism of xenobiotic detoxication genes in patients with iron deficiency anemia]
Aneurysm
Factors Predictive of Subretinal Fluid Resolution in Coats Disease: Analysis of 177 Eyes in 177 Patients at a Single Center.
Aneurysm
Predictors of enucleation in Coats disease: analysis of 259 eyes of 259 patients at a single center.
Aneurysm, Dissecting
99-Case Study of Sporadic Aortic Dissection by Whole Exome Sequencing Indicated Novel Disease-Associated Genes and Variants in Chinese Population.
Anus, Imperforate
EP300-related Rubinstein-Taybi syndrome: Highlighted rare phenotypic findings and a genotype-phenotype meta-analysis of 74 patients.
Anus, Imperforate
Exome Sequencing Identification of EP300 Mutation in a Proband with Coloboma and Imperforate Anus: Possible Expansion of the Phenotypic Spectrum of Rubinstein-Taybi Syndrome.
Aortic Aneurysm
Aortic aneurysm: An underestimated serious finding in the EP300 mutation phenotypical spectrum.
Aortic Aneurysm, Abdominal
Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm.
Aortic Aneurysm, Abdominal
The role of circadian clock gene BMAL1 in vascular proliferation.
Aortic Aneurysm, Abdominal
Turning back the clock: regression of abdominal aortic aneurysms via pharmacotherapy.
Apnea
Physiological changes in response to apnea impact the timing of motor representations: a preliminary study.
Apnea
Prevalence of sleep apnea among Japanese industrial workers determined by a portable sleep monitoring system.
Apraxias
Relationship between clock and star drawing and the degree of hepatic encephalopathy.
Apraxias
The Clock Test: a sensitive measure to differentiate normal elderly from those with Alzheimer disease.
Arrhythmias, Cardiac
A 13.34?W Event-driven Patient-specific ANN Cardiac Arrhythmia Classifier for Wearable ECG Sensors.
Arrhythmias, Cardiac
Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress.
Arrhythmias, Cardiac
Circadian rhythm. Dysrhythmia in the suprachiasmatic nucleus inhibits memory processing.
Arrhythmias, Cardiac
Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice.
Arrhythmias, Cardiac
Drosophila melanogaster deficient in protein kinase A manifests behavior-specific arrhythmia but normal clock function.
Arrhythmias, Cardiac
Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis.
Arrhythmias, Cardiac
Effect of reoxygenation on the electrical stability of the rat heart in vivo: a chronobiological study.
Arrhythmias, Cardiac
Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless.
Arrhythmias, Cardiac
PHYTOCLOCK 1 encoding a novel GARP protein essential for the Arabidopsis circadian clock.
Arrhythmias, Cardiac
Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A.
Arrhythmias, Cardiac
Prolonged QT intervals in mice with cardiomyocyte-specific deficiency of the molecular clock.
Arrhythmias, Cardiac
The Cardiomyocyte Molecular Clock, Regulation of Scn5a and Arrhythmia Susceptibility.
Arrhythmias, Cardiac
The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer's disease.
Arrhythmias, Cardiac
The Myb domain of LUX ARRHYTHMO in complex with DNA: expression, purification and crystallization.
Arrhythmias, Cardiac
The search for circadian rhythm pacemakers in the light of lesion experiments.
Arrhythmias, Cardiac
Transcriptomal dissection of soybean circadian rhythmicity in two geographically, phenotypically and genetically distinct cultivars.
Arteriosclerosis
Tissue-intrinsic dysfunction of circadian clock confers transplant arteriosclerosis.
Arthritis
Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.
Arthritis
Melatonin attenuates clock gene Cryptochrome1, which may aggravates mouse anti-type II collagen antibody-induced arthritis.
Arthritis
The circadian regulator Bmal1 in joint mesenchymal cells regulates both joint development and inflammatory arthritis.
Arthritis, Rheumatoid
Adverse effects of sulfasalazine in patients with rheumatoid arthritis are associated with diplotype configuration at the N-acetyltransferase 2 gene.
Arthritis, Rheumatoid
Clock gene expression in different synovial cells of patients with rheumatoid arthritis and osteoarthritis.
Arthritis, Rheumatoid
DEC2 Blocks the Effect of the ARNTL2/NPAS2 Dimer on the Expression of PER3 and DBP.
Arthritis, Rheumatoid
Delphinidin, a specific inhibitor of histone acetyltransferase, suppresses inflammatory signaling via prevention of NF-?B acetylation in fibroblast-like synoviocyte MH7A cells.
Arthritis, Rheumatoid
Differentially Expressed in Chondrocytes 2 (DEC2) Increases the Expression of IL-1? and Is Abundantly Present in Synovial Membrane in Rheumatoid Arthritis.
Arthritis, Rheumatoid
Effect of Circadian Rhythm on Clinical and Pathophysiological Conditions and Inflammation.
Arthritis, Rheumatoid
Imbalance between HAT and HDAC Activities in the PBMCs of Patients with Ankylosing Spondylitis or Rheumatoid Arthritis and Influence of HDAC Inhibitors on TNF Alpha Production.
Arthritis, Rheumatoid
Implications of transcriptional coactivator CREB binding protein complexes in rheumatoid arthritis.
Arthritis, Rheumatoid
Increased genotype frequency of N-acetyltransferase 2 slow acetylation in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
Interactions between the genes that regulate the body clock and those that worsen rheumatoid arthritis.
Arthritis, Rheumatoid
Involvement of the circadian rhythm and inflammatory cytokines in the pathogenesis of rheumatoid arthritis.
Arthritis, Rheumatoid
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes.
Arthritis, Rheumatoid
N-acetyltransferase 2 genotype-related efficacy of sulfasalazine in patients with rheumatoid arthritis.
Arthritis, Rheumatoid
N-acetyltransferase-2 genotypes among patients with rheumatoid arthritis attending jordan university hospital.
Arthritis, Rheumatoid
The influence of N-acetyltransferase 2 polymorphism on rheumatoid arthritis activity.
Arthritis, Rheumatoid
TNF-? induces expression of the circadian clock gene Bmal1 via dual calcium-dependent pathways in rheumatoid synovial cells.
Arthritis, Rheumatoid
TNF-? modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells.
Asthma
A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.
Asthma
Acetyl-CoA:lyso-platelet-activating factor acetyltransferase activity in neutrophils from asthmatic patients and normal subjects.
Asthma
Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma.
Asthma
Association of circadian clock TIMELESS variants and expression with asthma risk in children.
Asthma
Basophil degranulation in response to IgE ligation is controlled by a distinctive circadian clock in asthma.
Asthma
Characterization of the human mucin 5AC promoter and its regulation by the histone acetyltransferase P300.
Asthma
Circadian rhythms in the CNS and peripheral clock disorders: function of clock genes: influence of medication for bronchial asthma on circadian gene.
Asthma
Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.
Asthma
Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma.
Asthma
Knowledge and attitudes of American physicians and public about medical chronobiology and chronotherapeutics. Findings of two 1996 Gallup surveys.
Asthma
Magnesium depletion with hypo- or hyper- function of the biological clock may be involved in chronopathological forms of asthma.
Asthma
N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk.
Asthma
Optimization of dosing schedule of daily inhalant dexamethasone to minimize phase shifting of clock gene expression rhythm in the lungs of the asthma mouse model.
Asthma
Polymorphisms of N-acetyltransferase 2, glutathione S-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis.
Asthma
Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma.
Asthma
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.
Asthma
Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.
Asthma
The circadian protein BMAL1 in myeloid cells is a negative regulator of allergic asthma.
Asthma
[Roles of histone acetyltransferase and histone deacetylase in the pathogenesis of bronchial asthma].
Astigmatism
Assessment of a software guided system to reduce pre-existing astigmatism in cataract surgery.
Astrocytoma
[Increased Egr-1 binding to promoter induced by histone hyperacetylation promotes gdnf gene transcription].
Ataxia
BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways.
Ataxia
DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin.
Ataxia Telangiectasia
Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-X(L) and survivin.
Ataxia Telangiectasia
MYST family lysine acetyltransferase facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii.
Ataxia Telangiectasia
SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair.
Ataxia Telangiectasia
The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60.
Ataxia Telangiectasia
Tip60 in DNA damage response and growth control: many tricks in one HAT.
Ataxia Telangiectasia
Tip60 is associated with resistance to X-ray irradiation in prostate cancer.
Atherosclerosis
Activated p300 acetyltransferase activity modulates aortic valvular calcification with osteogenic transdifferentiation and downregulation of Klotho.
Atherosclerosis
Altered Clock and Lipid Metabolism-Related Genes in Atherosclerotic Mice Kept with Abnormal Lighting Condition.
Atherosclerosis
Angiotensin II Suppresses Rev-erb? Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor ? Pathway.
Atherosclerosis
Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
Atherosclerosis
BMAL1-Downregulation Aggravates Porphyromonas Gingivalis-Induced Atherosclerosis by Encouraging Oxidative Stress.
Atherosclerosis
Circadian locomotor output cycles kaput accelerates atherosclerotic plaque formation by upregulating plasminogen activator inhibitor-1 expression.
Atherosclerosis
Clock-Bmal1 mediates MMP9 induction in acrolein-promoted atherosclerosis associated with gut microbiota regulation.
Atherosclerosis
Curing atherosclerosis should be the next major cardiovascular prevention goal.
Atherosclerosis
Effect of hyperlipidemia on the expression of circadian genes in apolipoprotein E knock-out atherosclerotic mice.
Atherosclerosis
Histone acetylation and methylation significantly change with severity of atherosclerosis in human carotid plaques.
Atherosclerosis
Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis.
Atherosclerosis
Hyper nuclear acetylation (HNA) in proliferation, differentiation and apoptosis.
Atherosclerosis
Impaired Cholesterol Metabolism and Enhanced Atherosclerosis in Clock Mutant Mice.
Atherosclerosis
MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions.
Atherosclerosis
Overexpression of CRY1 protects against the development of atherosclerosis via the TLR/NF-?B pathway.
Atherosclerosis
P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.
Atherosclerosis
Regulation of circadian rhythms by NEAT1 mediated TMAO-induced endothelial proliferation: A protective role of asparagus extract.
Atherosclerosis
Rhythm changes of clock genes, apoptosis-related genes and atherosclerosis-related genes in apolipoprotein E knockout mice.
Atherosclerosis
The orphan nuclear receptor Rev-erbalpha: a transcriptional link between circadian rhythmicity and cardiometabolic disease.
Atherosclerosis
Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival.
Atrial Fibrillation
Altered Expression of Circadian Clock Genes in Patients with Atrial Fibrillation Is Associated with Atrial High-Rate Episodes and Left Atrial Remodeling.
Atrial Fibrillation
Exercise-induced arterial hypertension - an independent factor for hypertrophy and a ticking clock for cardiac fatigue or atrial fibrillation in athletes?
Atrial Fibrillation
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
Atrial Fibrillation
The role of the calcium and the voltage clocks in sinoatrial node dysfunction.
Atrial Flutter
Progressive isthmus delay during atrial flutter ablation: the critical importance of isthmus spanning electrodes for distinguishing pseudoblock from block.
Autoimmune Diseases
Circadian clock genes as promising therapeutic targets for autoimmune diseases.
Autoimmune Diseases
Clock gene modulation by TNF-alpha depends on calcium and p38 MAP kinase signaling.
Autoimmune Diseases
DEC2 Blocks the Effect of the ARNTL2/NPAS2 Dimer on the Expression of PER3 and DBP.
Autoimmune Diseases
Dynamic interactions between TIP60 and p300 regulate FOXP3 function through a structural switch defined by a single lysine on TIP60.
Autoimmune Diseases
Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.
Autoimmune Diseases
TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription.
Autoimmune Diseases
TNFR1 is essential for CD40, but not for lipopolysaccharide-induced sickness behavior and clock gene dysregulation.
Bacteremia
Comparative Exoproteomics and Host Inflammatory Response in Staphylococcus aureus Skin and Soft Tissue Infections, Bacteremia, and Subclinical Colonization.
Bacterial Infections
A broad-spectrum antibiotic, DCAP, reduces uropathogenic Escherichia coli infection and enhances vorinostat anticancer activity by modulating autophagy.
Bacterial Infections
A Localized Pseudomonas syringae Infection Triggers Systemic Clock Responses in Arabidopsis.
Bacterial Infections
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Bacterial Infections
Bacterial Infection Disrupts Clock Gene Expression to Attenuate Immune Responses.
Bacterial Infections
Diel Variation in CC Chemokine Gene Expression in the Japanese Pufferfish Takifugu rubripes.
Barrett Esophagus
A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.
Barrett Esophagus
Correction: A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.
beta-n-acetylhexosaminidase deficiency
A fluorimetric enzyme assay for the diagnosis of Sanfilippo disease C (MPS III C).
Bicuspid Aortic Valve Disease
Upregulated microRNA?330?3p promotes calcification in the bicuspid aortic valve via targeting CREBBP.
Blepharophimosis
De novo KAT6B Mutation Identified with Whole-Exome Sequencing in a Girl with Say-Barber/Biesecker/Young-Simpson Syndrome.
Blepharophimosis
KAT6B Genetic Variant Identified in a Short Stature Chinese Infant: A Report of Physical Growth in Clinical Spectrum of KAT6B-Related Disorders.
Blepharoptosis
Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice.
Blindness
A switch from diurnal to nocturnal activity in S. ehrenbergi is accompanied by an uncoupling of light input and the circadian clock.
Blindness
RNA Splicing Factor Mutations That Cause Retinitis Pigmentosa Result in Circadian Dysregulation.
Blister
Evidence for a central role of transcription in the timing mechanism of a circadian clock.
Bone Diseases, Metabolic
Identification of Differential Genes Expression Profiles and Pathways of Bone Marrow Mesenchymal Stem Cells of Adolescent Idiopathic Scoliosis Patients by Microarray and Integrated Gene Network Analysis.
Bone Resorption
Collagen fragments in urine derived from bone resorption are highly racemized and isomerized: a biological clock of protein aging with clinical potential.
Bowen's Disease
[Disseminated Bowen's disease 20 years after the handling of radioactive products in the clock manufacture]
Brachydactyly
Impaired Regulation of Histone Methylation and Acetylation Underlies Specific Neurodevelopmental Disorders.
Bradycardia
New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: bradycardic effects of ivabradine are linked to suppression of intracellular Ca²? cycling.
Bradycardia
Pacemaker Gene Mutations, Bradycardia, Arrhythmias and the Coupled Clock Theory.
Bradycardia
RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.
Brain Concussion
Executive clock drawing correlates with performance-based functional status in people with combat-related mild traumatic brain injury and comorbid posttraumatic stress disorder.
Brain Diseases
Relationship between clock and star drawing and the degree of hepatic encephalopathy.
Brain Diseases
The discovery of circadian clock genes and the use of similar strategies to discover unknown genes underlying complex behaviors and brain disorders.
Brain Edema
Subtle Cognitive Dysfunction in Resolving High Altitude Cerebral Edema Revealed by a Clock Drawing Test.
Brain Edema
Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT.
Brain Infarction
Microbleeds and silent brain infarctions are differently associated with cognitive dysfunction in patients with advanced periventricular leukoaraiosis.
Brain Injuries
Monitoring anoxic depolarization at the bedside: A step closer to the 24th century.
Brain Injuries
The role of a lncRNA (TCONS_00044595) in regulating pineal CLOCK expression after neonatal hypoxia-ischemia brain injury.
Brain Injuries
The role of miR-182 in regulating pineal CLOCK expression after hypoxia-ischemia brain injury in neonatal rats.
Brain Injuries, Traumatic
Clock drawing and mini-mental state examination in patients with traumatic brain injury.
Brain Injuries, Traumatic
Evaluation of Cognitive Functions in Traumatic Brain Injury Patients Using Mini Mental State Examination and Clock Drawing Test.
Brain Injuries, Traumatic
Neuroanatomical correlates of the clock drawing test in patients with traumatic brain injury.
Brain Injuries, Traumatic
Regulation of Circadian Clock Genes on Sleep Disorders in Traumatic Brain Injury Patients.
Brain Injuries, Traumatic
Revisiting the neuroanatomical correlates of the clock drawing test among persons with traumatic brain injury.
Brain Injuries, Traumatic
Sleep-wake disturbances in hospitalized patients with traumatic brain injury: association with brain trauma but not with an abnormal melatonin circadian rhythm.
Brain Injuries, Traumatic
THE MOLECULAR MECHANISMS AFFECTING N-ACETYLASPARTATE HOMEOSTASIS FOLLOWING EXPERIMENTAL GRADED TRAUMATIC BRAIN INJURY.
Brain Ischemia
Brain tissue sodium is a ticking clock telling time after arterial occlusion in rat focal cerebral ischemia.
Brain Ischemia
Cyclic AMP response element binding protein (CREB) and CREB binding protein (CBP) in global cerebral ischemia.
Brain Ischemia
Increased Neuronal Injury in Clock Gene Per-1 Deficient-Mice after Cerebral Ischemia.
Brain Ischemia
Proton magnetic resonance spectroscopy as a time clock measurement device in cerebral ischemia.
Brain Ischemia
The Hippocampal Autophagic Machinery is Depressed in the Absence of the Circadian Clock Protein PER1 that may Lead to Vulnerability During Cerebral Ischemia.
Brain Ischemia
[Effects of Wulongdan on expression of pineal clock genes in rats with chronic cerebral ischemia].
Brain Neoplasms
Acetyl-coenzyme A: 1,4-diaminobutane N-acetyltransferase: activity in rat brain during development, in experimental brain tumours and in brains of fish of different metabolic activity.
Brain Neoplasms
Direct interaction of Gas41 and Myc encoded by amplified genes in nervous system tumours.
Brain Neoplasms
DNA methylation-based age estimation in pediatric healthy tissues and brain tumors.
Brain Neoplasms
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Breast Neoplasms
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
Breast Neoplasms
4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
Breast Neoplasms
A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology.
Breast Neoplasms
A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer.
Breast Neoplasms
A network-based approach to identify disease-associated gene modules through integrating DNA methylation and gene expression.
Breast Neoplasms
A novel deep autoencoder based survival analysis approach for microarray dataset.
Breast Neoplasms
Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer.
Breast Neoplasms
Active cigarette smoking and the risk of breast cancer at the level of N-acetyltransferase 2 (NAT2) gene polymorphisms.
Breast Neoplasms
Active smoking and secondhand smoke increase breast cancer risk: the report of the Canadian Expert Panel on Tobacco Smoke and Breast Cancer Risk (2009).
Breast Neoplasms
Altered circadian genes expression in breast cancer tissue according to the clinical characteristics.
Breast Neoplasms
Analyses of BMAL1 and PER2 Oscillations in a Model of Breast Cancer Progression Reveal Changes With Malignancy.
Breast Neoplasms
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway.
Breast Neoplasms
ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.
Breast Neoplasms
Assembly of a comprehensive regulatory network for the mammalian circadian clock: a bioinformatics approach.
Breast Neoplasms
Association between N-acetyltransferase 2 (NAT2) genetic polymorphism and development of breast cancer in post-menopausal Chinese women in Taiwan, an area of great increase in breast cancer incidence.
Breast Neoplasms
Association of NAT2 and smoking in relation to breast cancer incidence in a population-based case-control study (United States).
Breast Neoplasms
Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer.
Breast Neoplasms
BRCA1 and BRCA2 Gene Expression: Diurnal Variability and Influence of Shift Work
Breast Neoplasms
Breast cancer and active and passive smoking: the role of the N-acetyltransferase 2 genotype.
Breast Neoplasms
Breast cancer risk, meat consumption and N-acetyltransferase (NAT2) genetic polymorphisms.
Breast Neoplasms
Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype.
Breast Neoplasms
Breast cancer, passive and active cigarette smoking and N-acetyltransferase 2 genotype.
Breast Neoplasms
Cancer stem cell generation during epithelial-mesenchymal transition is temporally gated by intrinsic circadian clocks.
Breast Neoplasms
Case-control study of breast cancer in India: Role of PERIOD3 clock gene length polymorphism and chronotype.
Breast Neoplasms
CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells.
Breast Neoplasms
CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers.
Breast Neoplasms
Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen.
Breast Neoplasms
Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms, and breast cancer risk.
Breast Neoplasms
Cigarette smoking, N-acetyltransferase 2 genotypes, and breast cancer risk: pooled analysis and meta-analysis.
Breast Neoplasms
Circadian clock gene Per2 downregulation in non?small cell lung cancer is associated with tumour progression and metastasis.
Breast Neoplasms
Circadian clock manipulation for cancer prevention and control and the relief of cancer symptoms.
Breast Neoplasms
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
Breast Neoplasms
CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses.
Breast Neoplasms
CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-?
Breast Neoplasms
Combined effect of CYP1B1 codon 432 polymorphism and N-acetyltransferase 2 slow acetylator phenotypes in relation to breast cancer in the Turkish population.
Breast Neoplasms
Concentration Dependence of the Unbound Partition Coefficient Kpuu and Its Application to Correct for Exposure-Related Discrepancies between Biochemical and Cellular Potency of KAT6A Inhibitors.
Breast Neoplasms
Consumption of red and processed meat and breast cancer incidence: A systematic review and meta-analysis of prospective studies.
Breast Neoplasms
Correction to "High N-Acetyltransferase 1 5?-androstane-3?, Expression is Associated with Estrogen Receptor Expression in Breast Tumors, but is not Under Direct Regulation by Estradiol, 17?-Diol, or Dihydrotestosterone in Breast Cancer Cells".
Breast Neoplasms
Correction to: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Breast Neoplasms
Correlation of Expression of Human Arrest-Defective-1 (hARD1) Protein With Breast Cancer.
Breast Neoplasms
Correlation of expression of human arrest-defective-1 (hARD1) protein with breast cancer.
Breast Neoplasms
Deciphering the Molecular Basis of Melatonin Protective Effects on Breast Cells Treated with Doxorubicin: TWIST1 a Transcription Factor Involved in EMT and Metastasis, a Novel Target of Melatonin.
Breast Neoplasms
Decreased expression of microRNA-17 and microRNA-20b promotes breast cancer resistance to taxol therapy by upregulation of NCOA3.
Breast Neoplasms
Digging Deeper into Breast Cancer Epigenetics: Insights from Chemical Inhibition of Histone Acetyltransferase TIP60 In Vitro.
Breast Neoplasms
DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility.
Breast Neoplasms
Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm.
Breast Neoplasms
E1A-mediated repression of progesterone receptor-dependent transactivation involves inhibition of the assembly of a multisubunit coactivation complex.
Breast Neoplasms
Effects of tamoxifen on DNA adduct formation and arylamines N-acetyltransferase activity in human breast cancer cells.
Breast Neoplasms
Elevated GCN5 expression confers tamoxifen resistance by upregulating AIB1 expression in ER-positive breast cancer.
Breast Neoplasms
Entrainment of breast (cancer) epithelial cells detects distinct circadian oscillation patterns for clock and hormone receptor genes.
Breast Neoplasms
EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer.
Breast Neoplasms
EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.
Breast Neoplasms
Epigenetic biomarker screening by FLIM-FRET for combination therapy in ER+ breast cancer.
Breast Neoplasms
Epigenetic impact of long-term shiftwork: pilot evidence from circadian genes and whole-genome methylation analysis.
Breast Neoplasms
Estrogen receptor alpha (ERalpha) mediates 17beta-estradiol (E2)-activated expression of HBO1.
Breast Neoplasms
Estrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells.
Breast Neoplasms
Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors.
Breast Neoplasms
Extracellular Acidosis Promotes Metastatic Potency via Decrease of the BMAL1 Circadian Clock Gene in Breast Cancer.
Breast Neoplasms
Fe65 Suppresses Breast Cancer Cell Migration and Invasion through Tip60 Mediated Cortactin Acetylation.
Breast Neoplasms
Frequent overexpression of the cyclin D1 oncogene in invasive lobular carcinoma of the breast.
Breast Neoplasms
Function of GCN5 in the TGF-?1-induced epithelial-to-mesenchymal transition in breast cancer.
Breast Neoplasms
Genetic alterations and oncogenic pathways associated with breast cancer subtypes.
Breast Neoplasms
Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.
Breast Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Breast Neoplasms
GSTM1 null genotype, red meat consumption and breast cancer risk (The Netherlands).
Breast Neoplasms
Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells.
Breast Neoplasms
Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases.
Breast Neoplasms
High levels of ?-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer.
Breast Neoplasms
High N-Acetyltransferase 1 Expression Is Associated with Estrogen Receptor Expression in Breast Tumors, but Is not Under Direct Regulation by Estradiol, 5
Breast Neoplasms
Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells.
Breast Neoplasms
Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176.
Breast Neoplasms
Identification of a panel of MYC and Tip60 co-regulated genes functioning primarily in cell cycle and DNA replication.
Breast Neoplasms
Identification of an estrogen-regulated circadian mechanism necessary for breast acinar morphogenesis.
Breast Neoplasms
Identification of MYST3 as a novel epigenetic activator of ER? frequently amplified in breast cancer.
Breast Neoplasms
Identification of the major promoter and non-coding exons of the human arylamine N-acetyltransferase 1 gene (NAT1).
Breast Neoplasms
Identification of valid reference genes for circadian gene-expression studies in human mammary epithelial cells.
Breast Neoplasms
Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo.
Breast Neoplasms
Implications of a peroxisome proliferator-activated receptor alpha (PPAR?) ligand clofibrate in breast cancer.
Breast Neoplasms
Induction of the CLOCK gene by E2-ER? signaling promotes the proliferation of breast cancer cells.
Breast Neoplasms
Influence of night-shift and napping at work on urinary melatonin, 17-ß-estradiol and clock gene expression in pre-menopausal nurses.
Breast Neoplasms
Influence of the estrous cycle on clock gene expression in reproductive tissues: effects of fluctuating ovarian steroid hormone levels.
Breast Neoplasms
Inhibition of N-acetyltransferase 10 using remodelin attenuates doxorubicin resistance by reversing the epithelial-mesenchymal transition in breast cancer.
Breast Neoplasms
KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
Breast Neoplasms
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Breast Neoplasms
Kinetics of arylamine N-acetyltransferase in tissues from human breast cancer.
Breast Neoplasms
leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3.
Breast Neoplasms
LINC01857 as an oncogene regulates CREB1 activation by interacting with CREBBP in breast cancer.
Breast Neoplasms
Loss of circadian clock gene expression is associated with tumor progression in breast cancer.
Breast Neoplasms
Master Regulators of Signaling Pathways: An Application to the Analysis of Gene Regulation in Breast Cancer.
Breast Neoplasms
Mechanisms of Breast Cancer in Shift Workers: DNA Methylation in Five Core Circadian Genes in Nurses Working Night Shifts.
Breast Neoplasms
Metagenomic characterization of KATs in human cancer and their association with clinic-pathological features.
Breast Neoplasms
miR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300.
Breast Neoplasms
Molecular cloning of xSRC-3, a novel transcription coactivator from Xenopus, that is related to AIB1, p/CIP, and TIF2.
Breast Neoplasms
Mutational landscape implicates epithelial-mesenchymal transition gene TGF-?2 mutations for uterine carcinosarcoma after adjuvant tamoxifen therapy for breast carcinoma.
Breast Neoplasms
MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis.
Breast Neoplasms
N-acetyltransferase (NAT1, NAT2) and glutathione S-transferase (GSTM1, GSTT1) polymorphisms in breast cancer.
Breast Neoplasms
N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population.
Breast Neoplasms
N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk.
Breast Neoplasms
N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines.
Breast Neoplasms
N-acetyltransferase 2 (NAT2) genotypes, cigarette smoking, and the risk of breast cancer.
Breast Neoplasms
N-acetyltransferase 2 Genotype Modification of Active Cigarette Smoking on Breast Cancer Risk Among Hispanic and non-Hispanic White Women.
Breast Neoplasms
N-acetyltransferase 2 polymorphism and breast cancer risk with smoking: a case control study in Japanese women.
Breast Neoplasms
N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.
Breast Neoplasms
N-acetyltransferase 2, exposure to aromatic and heterocyclic amines, and receptor-defined breast cancer.
Breast Neoplasms
NAT2 polymorphisms combining with smoking associated with breast cancer susceptibility: a meta-analysis.
Breast Neoplasms
NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1?- and AP-1-mediated VEGFa transcription.
Breast Neoplasms
Night shift work and risk of breast cancer in women: the Generations Study cohort.
Breast Neoplasms
Night-shift work, circadian and melatonin pathway related genes and their interaction on breast cancer risk: evidence from a case-control study in Korean women.
Breast Neoplasms
No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Breast Neoplasms
Oscillation of clock and clock controlled genes induced by serum shock in human breast epithelial and breast cancer cells: regulation by melatonin.
Breast Neoplasms
p33(ING1b) stimulates the transcriptional activity of the estrogen receptor alpha via its activation function (AF) 2 domain.
Breast Neoplasms
PARP1 Co-Regulates EP300-BRG1-Dependent Transcription of Genes Involved in Breast Cancer Cell Proliferation and DNA Repair.
Breast Neoplasms
Peritumoural versus subareolar administration of technetium-99m nanocolloid for sentinel lymph node detection in breast cancer: preliminary results of a prospective intra-individual comparative study.
Breast Neoplasms
Pharmacological Inhibition of CBP/p300 Blocks Estrogen Receptor Alpha (ER?) Function through Suppressing Enhancer H3K27 Acetylation in Luminal Breast Cancer.
Breast Neoplasms
Polymorphisms in circadian genes, night work and breast cancer: results from the GENICA study.
Breast Neoplasms
Polymorphisms in Xenobiotic Metabolizing Genes, Intakes of Heterocyclic Amines and Red Meat, and Postmenopausal Breast Cancer.
Breast Neoplasms
Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias.
Breast Neoplasms
Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
Breast Neoplasms
Promoter hypomethylation of the N-acetyltransferase 1 gene in breast cancer.
Breast Neoplasms
Pygo2 associates with MLL2 histone methyltransferase (HMT) and GCN5 histone acetyltransferase (HAT) complexes to augment Wnt target gene expression and breast cancer stem-like cell expansion.
Breast Neoplasms
Rational design and validation of a Tip60 histone acetyltransferase inhibitor.
Breast Neoplasms
Regulation of estrogen-mediated cell survival and proliferation by p160 coactivators.
Breast Neoplasms
Risk of breast cancer after night- and shift work: current evidence and ongoing studies in denmark.
Breast Neoplasms
Rotating-shift nurses after a day off: peripheral clock gene expression, urinary melatonin, and serum 17-?-estradiol levels.
Breast Neoplasms
Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems.
Breast Neoplasms
Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis.
Breast Neoplasms
Smoking (active and passive), N-acetyltransferase 2, and risk of breast cancer.
Breast Neoplasms
Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer.
Breast Neoplasms
Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation.
Breast Neoplasms
SULT1A1 genotype, active and passive smoking, and breast cancer risk by age 50 years in a German case-control study.
Breast Neoplasms
The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
Breast Neoplasms
The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.
Breast Neoplasms
The adenoviral E1A N-terminal domain represses MYC transcription in human cancer cells by targeting both p300 and TRRAP and inhibiting MYC promoter acetylation of H3K18 and H4K16.
Breast Neoplasms
The association of polymorphic N-acetyltransferase (NAT2) with breast cancer risk.
Breast Neoplasms
The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day.
Breast Neoplasms
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma.
Breast Neoplasms
The LIM protein Ajuba recruits DBC1 and CBP/p300 to acetylate ER? and enhances ER? target gene expression in breast cancer cells.
Breast Neoplasms
The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome.
Breast Neoplasms
The role and regulation of the nuclear receptor co-activator AIB1 in breast cancer.
Breast Neoplasms
The role of polymorphisms in circadian pathway genes in breast tumorigenesis.
Breast Neoplasms
Time will tell: Circadian clock dysregulation in triple negative breast cancer.
Breast Neoplasms
TIP60 Histone Acetyltransferase in Adipose Tissue: Possible Linkages with Breast Cancer Development?
Breast Neoplasms
TIP60 Inhibitor TH1834 Reduces Breast Cancer Progression in Xenografts in Mice.
Breast Neoplasms
TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.
Breast Neoplasms
TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer.
Breast Neoplasms
TIP60: an actor in acetylation of H3K4 and tumor development in breast cancer.
Breast Neoplasms
Transcriptional regulation of the transforming growth factor beta type II receptor gene by histone acetyltransferase and deacetylase is mediated by NF-Y in human breast cancer cells.
Breast Neoplasms
Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Breast Neoplasms
Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world.
Breast Neoplasms
Working against our endogenous circadian clock: Breast cancer and electric lighting in the modern world.
Breast Neoplasms
[Association of genetic variantions of circadian clock genes and risk of breast cancer].
Breast Neoplasms
[hARD1 antiserum preparation and primary immunohistochemical analysis of hARD1 in tumor tissues]
Breast Neoplasms
[Molecular mechanism of inhibition of sodium butyrate on activation of tumor associated aromatase promoters]
Breast Neoplasms
[Night work as a possible risk factor for breast cancer in nurses. Correlation between the onset of tumors and alterations in blood melatonin levels]
Breast Neoplasms
[Production of anti-recombinant human arrest defective 1 protein (hARD1) monoclonal antibodies for assaying human breast cancer tissues]
Breast Neoplasms
[The relationship between passive smoking, breast cancer risk and n-acetyltransferase 2 (NAT2)].
Bronchiolitis, Viral
BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Burkitt Lymphoma
GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways.
Carcinogenesis
"US-JAPAN CONFERENCE: INFLAMMATION, DIABETES AND CANCER" held at the Beckman Research Institute of City of Hope, Duarte, CA, USA.
Carcinogenesis
2-Aminofluorene-DNA adduct levels in tumor-target and nontarget organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus.
Carcinogenesis
A novel long noncoding RNA linc00460 upregulated by CBP/P300 promotes carcinogenesis in Esophageal Squamous Cell Carcinoma.
Carcinogenesis
A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation.
Carcinogenesis
A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.
Carcinogenesis
A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease.
Carcinogenesis
Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics.
Carcinogenesis
Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure.
Carcinogenesis
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9.
Carcinogenesis
Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
Carcinogenesis
Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors.
Carcinogenesis
An Artificial CTCF Peptide Triggers Efficient Therapeutic Efficacy in Ocular Melanoma.
Carcinogenesis
Analysis of the Circadian Regulation of Cancer Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington's Disease.
Carcinogenesis
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation.
Carcinogenesis
Artificial lighting in the industrialized world: circadian disruption and breast cancer.
Carcinogenesis
Association of N-acetyltransferase polymorphism and environmental factors with bladder carcinogenesis. Study in a north German population.
Carcinogenesis
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.
Carcinogenesis
c-MYC targets the central oscillator gene Per1 and is regulated by the circadian clock at the post-transcriptional level.
Carcinogenesis
Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK.
Carcinogenesis
Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction.
Carcinogenesis
CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.
Carcinogenesis
Circadian Clock Gene Bmal1 Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma.
Carcinogenesis
Circadian clock pathway genes associated with colorectal cancer risk and prognosis.
Carcinogenesis
Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124.
Carcinogenesis
Circadian protein BMAL1 promotes breast cancer cell invasion and metastasis by up-regulating matrix metalloproteinase9 expression.
Carcinogenesis
Circadian regulation of cell cycle: Molecular connections between aging and the circadian clock.
Carcinogenesis
Circadian variations of clock gene Per2 and cell cycle genes in different stages of carcinogenesis in golden hamster buccal mucosa.
Carcinogenesis
Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.
Carcinogenesis
CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses.
Carcinogenesis
Correlation between deregulated expression of PER2 gene and degree of glioma malignancy.
Carcinogenesis
Correlation between miRNAs and target genes in response to Campylobacter jejuni inoculation in chicken.
Carcinogenesis
Correlation of Expression of Human Arrest-Defective-1 (hARD1) Protein With Breast Cancer.
Carcinogenesis
Correlation of expression of human arrest-defective-1 (hARD1) protein with breast cancer.
Carcinogenesis
CREBBP knockdown suppressed proliferation and promoted chemo-sensitivity via PERK-mediated unfolded protein response in ovarian cancer.
Carcinogenesis
Daily rhythm variations of the clock gene PER1 and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma.
Carcinogenesis
Deregulated expression of circadian clock and clock-controlled cell cycle genes in chronic lymphocytic leukemia.
Carcinogenesis
Deregulation of the circadian clock constitutes a significant factor in tumorigenesis: a clockwork cancer. Part I: clocks and clocking machinery.
Carcinogenesis
Deregulation of the circadian clock constitutes a significant factor in tumorigenesis: a clockwork cancer. Part II. In vivo studies.
Carcinogenesis
Different roles of negative and positive components of the circadian clock in oncogene-induced neoplastic transformation.
Carcinogenesis
Differential gene expression profiles of hepatocellular carcinomas associated or not with viral infection.
Carcinogenesis
Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis.
Carcinogenesis
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2.
Carcinogenesis
Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis.
Carcinogenesis
E2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.
Carcinogenesis
Effects of aging and tumorigenesis on coupling between the circadian clock and cell cycle in colonic mucosa.
Carcinogenesis
Effects of light and food schedules on liver and tumor molecular clocks in mice.
Carcinogenesis
Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
Carcinogenesis
Enterotoxigenic Bacteroidesfragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3pf.
Carcinogenesis
Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
Carcinogenesis
Epithelial proliferation and expression of the aromatic amine activation enzyme N-acetyltransferase in the prostate of postnatal rat.
Carcinogenesis
Exciting History of Tip60 and Its Companions in Carcinogenesis Across the Heterochromatin Landscapes.
Carcinogenesis
Expression of Circadian Clock Genes in Human Colorectal Cancer Tissues Using Droplet Digital PCR.
Carcinogenesis
Expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates with location of tumor differently.
Carcinogenesis
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells.
Carcinogenesis
Expression of PER, CRY, and TIM genes for the pathological features of colorectal cancer patients.
Carcinogenesis
Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors.
Carcinogenesis
Expression pattern and prognostic value of circadian clock genes in pancreatic adenocarcinoma.
Carcinogenesis
Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300.
Carcinogenesis
Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.
Carcinogenesis
GCN5 inhibition prevents IL-6-induced prostate cancer metastases through PI3K/PTEN/Akt signaling by inactivating Egr-1.
Carcinogenesis
Glutathione S-transferase M1 genotype affects aminobiphenyl-hemoglobin adduct levels in white, black and Asian smokers and nonsmokers.
Carcinogenesis
Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors.
Carcinogenesis
Haploinsufficient tumor suppressor Tip60 negatively regulates oncogenic Aurora B kinase.
Carcinogenesis
High N-Acetyltransferase 1 Expression Is Associated with Estrogen Receptor Expression in Breast Tumors, but Is not Under Direct Regulation by Estradiol, 5
Carcinogenesis
Histone acetylation and chromatin signature in stem cell identity and cancer.
Carcinogenesis
Histone acetyltransferase 1 is a succinyltransferase for histones and non-histones and promotes tumorigenesis.
Carcinogenesis
Histone acetyltransferase hMOF promotes S phase entry and tumorigenesis in lung cancer.
Carcinogenesis
Histone Acetyltransferase MOF Orchestrates Outcomes at the Crossroad of Oncogenesis, DNA Damage Response, Proliferation, and Stem Cell Development.
Carcinogenesis
Histone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis.
Carcinogenesis
Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors.
Carcinogenesis
Histone deacetylation in epigenetics: an attractive target for anticancer therapy.
Carcinogenesis
Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues.
Carcinogenesis
Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo.
Carcinogenesis
Impaired light detection of the circadian clock in a zebrafish melanoma model.
Carcinogenesis
Increased expression of ESCO1 is correlated with poor patient survival and its role in human bladder cancer.
Carcinogenesis
Induction of the CBP transcriptional co-activator early during laryngeal carcinogenesis.
Carcinogenesis
Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice.
Carcinogenesis
Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment.
Carcinogenesis
Is there a role for molecular prognostic factors in the clinical management of ductal carcinoma in situ (DCIS) of the breast?
Carcinogenesis
It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes.
Carcinogenesis
Joint effects of the N-acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis.
Carcinogenesis
KAT2A succinyltransferase activity-mediated 14-3-3? upregulation promotes ?-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells.
Carcinogenesis
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Carcinogenesis
LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern.
Carcinogenesis
LPS promotes HBO1 stability via USP25 to modulate inflammatory gene transcription in THP-1 cells.
Carcinogenesis
Methods for In Vivo Functional Studies of Chromatin-Modifying Enzymes in Early Steps of Colon Carcinogenesis.
Carcinogenesis
microRNA-342-5p and miR-608 inhibit colon cancer tumorigenesis by targeting NAA10.
Carcinogenesis
MiR-596 activated by EP300 controls the tumorigenesis in epithelial ovarian cancer by declining BRD4 and KPNA4.
Carcinogenesis
MOF Regulates TNK2 Transcription Expression to Promote Cell Proliferation in Thyroid Cancer.
Carcinogenesis
Molecular dynamics simulations data of six compounds F3J-BRD4/CBP, EX1-BRD4/CBP, and E2T-BRD4/CBP.
Carcinogenesis
Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.
Carcinogenesis
MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis.
Carcinogenesis
N-acetylbenzidine and N,N'-diacetylbenzidine formation by rat and human liver slices exposed to benzidine.
Carcinogenesis
N-acetyltransferase activity--a susceptibility factor in human bladder carcinogenesis.
Carcinogenesis
N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.
Carcinogenesis
N-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population.
Carcinogenesis
Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).
Carcinogenesis
Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains.
Carcinogenesis
Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301).
Carcinogenesis
Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer.
Carcinogenesis
PFKFB4 negatively regulated the expression of histone acetyltransferase GCN5 to mediate the tumorigenesis of thyroid cancer.
Carcinogenesis
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
Carcinogenesis
Protein acetylation: more than chromatin modification to regulate transcription.
Carcinogenesis
Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer.
Carcinogenesis
Review article: a conceptual approach to understanding the molecular mechanisms of cancer development in Barrett's oesophagus.
Carcinogenesis
RNAi screening identifies HAT1 as a potential drug target in esophageal squamous cell carcinoma.
Carcinogenesis
Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer.
Carcinogenesis
Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis.
Carcinogenesis
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.
Carcinogenesis
Sea-Blue Histiocytosis of Bone Marrow in a Patient with t(8;22) Acute Myeloid Leukemia.
Carcinogenesis
Short-chain fatty acid inhibitors of histone deacetylases: promising anticancer therapeutics?
Carcinogenesis
SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation.
Carcinogenesis
Skp2 Deficiency Inhibits Chemical Skin Tumorigenesis Independent of p27(Kip1) Accumulation.
Carcinogenesis
Targeting Mybbp1a suppresses HCC progression via inhibiting IGF1/AKT pathway by CpG islands hypo-methylation dependent promotion of IGFBP5.
Carcinogenesis
Targeting the SAGA and ATAC transcriptional coactivator complexes in MYC-driven cancers.
Carcinogenesis
Tat-interactive Protein-60KDA (TIP60) Regulates the Tumorigenesis of Lung Cancer In Vitro.
Carcinogenesis
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
Carcinogenesis
The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.
Carcinogenesis
The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis.
Carcinogenesis
The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma.
Carcinogenesis
The circadian clock gene, Bmal1, regulates intestinal stem cell signaling and represses tumor initiation.
Carcinogenesis
The Circadian Clock in Skin: Implications for Adult Stem Cells, Tissue Regeneration, Cancer, Aging, and Immunity.
Carcinogenesis
The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.
Carcinogenesis
The Circadian Gene Clock Plays an Important Role in Cell Apoptosis and the DNA Damage Response In Vitro.
Carcinogenesis
The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments.
Carcinogenesis
The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells.
Carcinogenesis
The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma.
Carcinogenesis
The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model.
Carcinogenesis
The histone acetyltransferase TIP60 interacts with c-Myb and inactivates its transcriptional activity in human leukemia.
Carcinogenesis
The Impact of the Circadian Clock on Skin Physiology and Cancer Development.
Carcinogenesis
The Molecular Effects of Sulforaphane and Capsaicin on Metabolism upon Androgen and Tip60 Activation of Androgen Receptor.
Carcinogenesis
The overexpression of MYST4 in human solid tumors is associated with increased aggressiveness and decreased overall survival.
Carcinogenesis
The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.
Carcinogenesis
The tumor promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats.
Carcinogenesis
The Tumor Suppressor Roles of MYBBP1A, a Major Contributor to Metabolism Plasticity and Stemness.
Carcinogenesis
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Carcinogenesis
TIP60: an actor in acetylation of H3K4 and tumor development in breast cancer.
Carcinogenesis
Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.
Carcinogenesis
Up-regulation of human arrest-defective 1 protein is correlated with metastatic phenotype and poor prognosis in breast cancer.
Carcinogenesis
Watching the clock: endoplasmic reticulum-mediated control of circadian rhythms in cancer.
Carcinogenesis
ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
Carcinogenesis
[Circadian rhythm variation of the clock genes Per1 and cell cycle related genes in different stages of carcinogenesis of buccal mucosa in animal model].
Carcinogenesis
[Circadian variation of clock gene Per2 and cancer-related clock-controlled genes in buccal mucosa carcinoma of golden hamster at different cancer stages].
Carcinogenesis
[Identification of proteins interacting with the circadian clock protein PER1 in tumors using bacterial two-hybrid system technique].
Carcinogenesis
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
Carcinogenesis
[The progress of studies on the relation between circadian rhythm disruption and cancer].
Carcinoma
A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL.
Carcinoma
A novel long noncoding RNA linc00460 upregulated by CBP/P300 promotes carcinogenesis in Esophageal Squamous Cell Carcinoma.
Carcinoma
A role for the clock period circadian regulator 2 gene in regulating the clock gene network in human oral squamous cell carcinoma cells.
Carcinoma
A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer.
Carcinoma
Aberrant expression of clock gene period1 and its correlations with the growth, proliferation and metastasis of buccal squamous cell carcinoma.
Carcinoma
Altered expression of circadian clock genes in head and neck squamous cell carcinoma.
Carcinoma
Analysis of laser-microdissected prostate cancer tissues reveals potential tumor markers.
Carcinoma
Association between genetic polymorphisms of glutathione S-transferase P1 and N-acetyltransferase 2 and susceptibility to squamous-cell carcinoma of the esophagus.
Carcinoma
Association of N-acetyltransferase polymorphism and environmental factors with bladder carcinogenesis. Study in a north German population.
Carcinoma
CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.
Carcinoma
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.
Carcinoma
Circadian Clock Gene Bmal1 Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma.
Carcinoma
Circadian clock gene Per2 plays an important role in cell proliferation, apoptosis and cell cycle progression in human oral squamous cell carcinoma.
Carcinoma
Circadian clock is associated with tumor microenvironment in kidney renal clear cell carcinoma.
Carcinoma
Circadian variability of pharmacokinetics of 5-fluorouracil and CLOCK T3111C genetic polymorphism in patients with esophageal carcinoma.
Carcinoma
Daily rhythm variations of the clock gene PER1 and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma.
Carcinoma
Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells.
Carcinoma
Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex.
Carcinoma
Doxorubicin modulated clock genes and cytokines in macrophages extracted from tumor-bearing mice.
Carcinoma
DrugSniper, a Tool to Exploit Loss-Of-Function Screens, Identifies CREBBP as a Predictive Biomarker of VOLASERTIB in Small Cell Lung Carcinoma (SCLC).
Carcinoma
Dynamic Histone Acetylation of H3K4me3 Nucleosome Regulates MCL1 Pre-mRNA Splicing.
Carcinoma
Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.
Carcinoma
Epigenetic age acceleration of cervical squamous cell carcinoma converged to human papillomavirus 16/18 expression, immunoactivation, and favourable prognosis.
Carcinoma
Epigenetic change in kidney tumor: downregulation of histone acetyltransferase MYST1 in human renal cell carcinoma.
Carcinoma
Evaluation of EP300, a histone acetyletransferase, in patients with epithelial ovarian carcinoma.
Carcinoma
Expression and Prognostic Significance of EP300, TP53 and BAX in Clear Cell Renal Cell Carcinoma.
Carcinoma
Expression of p300 and p300/CBP associated factor (PCAF) in actinic keratosis and squamous cell carcinoma of the skin.
Carcinoma
Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.
Carcinoma
Genetic polymorphism of N-acetyltransferase 2 in the susceptibility to laryngeal squamous cell carcinoma.
Carcinoma
Gypenosides inhibited N-acetylation of 2-aminofluorene, N-acetyltransferase gene expression and DNA adduct formation in human cervix epithelioid carcinoma cells (HeLa).
Carcinoma
HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
Carcinoma
Histone acetyltransferase 1 upregulates androgen receptor expression to modulate CRPC cell resistance to enzalutamide.
Carcinoma
Human intestinal circadian clock: expression of clock genes in colonocytes lining the crypt.
Carcinoma
Identification of the SOX2 interactome by BioID reveals EP300 as a mediator of SOX2-dependent squamous differentiation and lung squamous cell carcinoma growth.
Carcinoma
Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo.
Carcinoma
KAT2A succinyltransferase activity-mediated 14-3-3? upregulation promotes ?-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells.
Carcinoma
KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma.
Carcinoma
LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.
Carcinoma
Loss of circadian clock gene expression is associated with tumor progression in breast cancer.
Carcinoma
Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway.
Carcinoma
Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
Carcinoma
Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes.
Carcinoma
N-acetyltransferase 2 genetic variants confer the susceptibility to head and neck carcinoma: evidence from 23 case-control studies.
Carcinoma
N-acetyltransferase 2 single-nucleotide polymorphisms and risk of gastric carcinoma.
Carcinoma
N-acetyltransferase phenotypes in bladder tumour patients with and without carcinoma in situ in selected site biopsies.
Carcinoma
New p53 related genes in human tumors: significant downregulation in colon and lung carcinomas.
Carcinoma
Novel o-Toluidine Metabolite in Rat Urine Associated with Urinary Bladder Carcinogenesis.
Carcinoma
o-Anisidine Dimer, 2-Methoxy-N4-(2-methoxyphenyl) Benzene-1,4-diamine, in Rat Urine Associated with Urinary bladder Carcinogenesis.
Carcinoma
Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma.
Carcinoma
Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells.
Carcinoma
Overexpression of retinoic acid receptor beta induces growth arrest and apoptosis in oral cancer cell lines.
Carcinoma
Overexpression of the clock gene Per2 suppresses oral squamous cell carcinoma progression by activating autophagy via the PI3K/AKT/mTOR pathway.
Carcinoma
Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301).
Carcinoma
PER1 and CLOCK are potential circulating biomarkers for head and neck squamous cell carcinoma.
Carcinoma
Polyamines regulate gene expression by stimulating translation of histone acetyltransferase mRNAs.
Carcinoma
Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils.
Carcinoma
Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?
Carcinoma
Solid-type adenoid cystic carcinoma of the breast, a distinct molecular entity enriched in NOTCH and CREBBP mutations.
Carcinoma
Synchronous ovarian and endometrial carcinomas in a patient with rubinstein-taybi syndrome: a case report and literature review.
Carcinoma
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Carcinoma
The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma.
Carcinoma
The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells.
Carcinoma
The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma.
Carcinoma
The oncogenic roles of nuclear receptor coactivator 1 in human esophageal carcinoma.
Carcinoma
The overexpression of MYST4 in human solid tumors is associated with increased aggressiveness and decreased overall survival.
Carcinoma
The p300/CBP associated factor: is frequently downregulated in intestinal-type gastric carcinoma and constitutes a biomarker for clinical outcome.
Carcinoma
Time-dependent effects of localized inflammation on peripheral clock gene expression in rats.
Carcinoma
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Carcinoma
Tip60-siRNA regulates ABCE1 acetylation to suppress lung cancer growth via activation of the apoptotic signaling pathway.
Carcinoma
[Circadian rhythm variation of the clock genes Per1 and cell cycle related genes in different stages of carcinogenesis of buccal mucosa in animal model].
Carcinoma
[Circadian variation of clock gene Per2 and cancer-related clock-controlled genes in buccal mucosa carcinoma of golden hamster at different cancer stages].
Carcinoma
[Effect of clock gene PER1 knockdown on clock gene networks in human oral squamous cell carcinoma].
Carcinoma
[Effects and mechanism of the circadian clock gene Per1 on the proliferation, apoptosis, cycle, and tumorigenicity in vivo of human oral squamous cell carcinoma].
Carcinoma
[Relationship between polymorphism of N-acetyltransferase 2 and genetic susceptibility to laryngeal carcinoma]
Carcinoma in Situ
N-acetyltransferase phenotypes in bladder tumour patients with and without carcinoma in situ in selected site biopsies.
Carcinoma, Adenoid Cystic
Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.
Carcinoma, Adenoid Cystic
Solid-type adenoid cystic carcinoma of the breast, a distinct molecular entity enriched in NOTCH and CREBBP mutations.
Carcinoma, Embryonal
P19 Cells as a Model for Studying the Circadian Clock in Stem Cells before and after Cell Differentiation.
Carcinoma, Endometrioid
Prognostic significance of elongator protein 3 expression in endometrioid adenocarcinoma.
Carcinoma, Endometrioid
The overexpression of MYST4 in human solid tumors is associated with increased aggressiveness and decreased overall survival.
Carcinoma, Hepatocellular
A long noncoding RNA perturbs the circadian rhythm of hepatoma cells to facilitate hepatocarcinogenesis.
Carcinoma, Hepatocellular
Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Clock gene expression in human and mouse hepatic models shows similar periodicity but different dynamics of variation.
Carcinoma, Hepatocellular
Corrigendum to "Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cells" [Canc. Lett. 469 (2020) 498-509].
Carcinoma, Hepatocellular
Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver.
Carcinoma, Hepatocellular
Deregulated expression of a novel component of TFTC/STAGA histone acetyltransferase complexes, rat SGF29, in hepatocellular carcinoma: possible implication for the oncogenic potential of c-Myc.
Carcinoma, Hepatocellular
Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines.
Carcinoma, Hepatocellular
Dysregulation of metallothionein and circadian genes in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha.
Carcinoma, Hepatocellular
Effect of norcantharidin on N-acetyltransferase activity in HepG2 cells.
Carcinoma, Hepatocellular
Epigenetic regulation of proliferation and invasion in hepatocellular carcinoma cells by CBP/p300 histone acetyltransferase activity.
Carcinoma, Hepatocellular
Escherichia coli Affects Expression of Circadian Clock Genes in Human Hepatoma Cells.
Carcinoma, Hepatocellular
Hepatitis B virus X protein disrupts the balance of the expression of circadian rhythm genes in hepatocellular carcinoma.
Carcinoma, Hepatocellular
High expression of N-acetyltransferase 10: a novel independent prognostic marker of worse outcome in patients with hepatocellular carcinoma.
Carcinoma, Hepatocellular
Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression.
Carcinoma, Hepatocellular
Histone acetyltransferase 1 promotes cells proliferation and induces cisplatin resistance in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling.
Carcinoma, Hepatocellular
Identification of rhythmic human CYPs and their circadian regulators using synchronized hepatoma cells.
Carcinoma, Hepatocellular
Impact of N-acetyltransferase polymorphism (NAT2) in hepatocellular carcinoma (HCC)--an investigation in a department of surgical medicine.
Carcinoma, Hepatocellular
Inaugural Article: A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades.
Carcinoma, Hepatocellular
Joint effect of polymorphism in the N-acetyltransferase 2 gene and smoking on hepatocellular carcinoma.
Carcinoma, Hepatocellular
Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells.
Carcinoma, Hepatocellular
Low Expression of KAT6B May Affect Prognosis in Hepatocellular Carcinoma.
Carcinoma, Hepatocellular
Melatonin modulates dysregulated circadian clocks in mice with diethylnitrosamine-induced hepatocellular carcinoma.
Carcinoma, Hepatocellular
miR-639 Expression Is Silenced by DNMT3A-Mediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer Cells.
Carcinoma, Hepatocellular
N-Acetyltransferase 10 Enhances Doxorubicin Resistance in Human Hepatocellular Carcinoma Cell Lines by Promoting the Epithelial-to-Mesenchymal Transition.
Carcinoma, Hepatocellular
N-Acetyltransferase-2, glutathione S-transferase M1 and T1 genetic polymorphisms, cigarette smoking and hepatocellular carcinoma: a case-control study.
Carcinoma, Hepatocellular
Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1-AMPK-mTOR axis.
Carcinoma, Hepatocellular
P300/CBP-associated factor (PCAF) inhibits the growth of hepatocellular carcinoma by promoting cell autophagy.
Carcinoma, Hepatocellular
Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma.
Carcinoma, Hepatocellular
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis.
Carcinoma, Hepatocellular
Role of N-acetyltransferase polymorphisms in hepatitis B related hepatocellular carcinoma: impact of smoking on risk.
Carcinoma, Hepatocellular
Targeting Mybbp1a suppresses HCC progression via inhibiting IGF1/AKT pathway by CpG islands hypo-methylation dependent promotion of IGFBP5.
Carcinoma, Hepatocellular
The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma.
Carcinoma, Hepatocellular
The histone acetyltransferase hMOF suppresses hepatocellular carcinoma growth.
Carcinoma, Hepatocellular
Time-dependent changes in proliferation, DNA damage and clock gene expression in hepatocellular carcinoma and healthy liver of a transgenic mouse model.
Carcinoma, Hepatocellular
Up regulation of NAT10 promotes metastasis of hepatocellular carcinoma cells through epithelial-to-mesenchymal transition.
Carcinoma, Hepatocellular
[Expression of PCAF in hepatocellular carcinoma and its clinical significance].
Carcinoma, Hepatocellular
[Relationship between genetic polymorphisms of N-acetyltransferase and susceptibility to hepatocellular carcinoma]
Carcinoma, Intraductal, Noninfiltrating
Is there a role for molecular prognostic factors in the clinical management of ductal carcinoma in situ (DCIS) of the breast?
Carcinoma, Lewis Lung
Doxorubicin modulated clock genes and cytokines in macrophages extracted from tumor-bearing mice.
Carcinoma, Neuroendocrine
SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString).
Carcinoma, Non-Small-Cell Lung
A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL.
Carcinoma, Non-Small-Cell Lung
Cytotoxic Effects of 24-Methylenecyloartanyl Ferulate on A549 Nonsmall Cell Lung Cancer Cells through MYBBP1A Up-Regulation and AKT and Aurora B Kinase Inhibition.
Carcinoma, Non-Small-Cell Lung
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Carcinoma, Non-Small-Cell Lung
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.
Carcinoma, Non-Small-Cell Lung
KAT2B is an immune infiltration-associated biomarker predicting prognosis and response to immunotherapy in non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.
Carcinoma, Non-Small-Cell Lung
Research on circadian clock genes in non-small-cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines.
Carcinoma, Ovarian Epithelial
Clinicopathological significance of circadian rhythm-related gene expression levels in patients with epithelial ovarian cancer.
Carcinoma, Ovarian Epithelial
Evaluation of EP300, a histone acetyletransferase, in patients with epithelial ovarian carcinoma.
Carcinoma, Ovarian Epithelial
MiR-596 activated by EP300 controls the tumorigenesis in epithelial ovarian cancer by declining BRD4 and KPNA4.
Carcinoma, Papillary
Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.
Carcinoma, Renal Cell
Epigenetic change in kidney tumor: downregulation of histone acetyltransferase MYST1 in human renal cell carcinoma.
Carcinoma, Renal Cell
Expression and Prognostic Significance of EP300, TP53 and BAX in Clear Cell Renal Cell Carcinoma.
Carcinoma, Renal Cell
NAA10 promotes proliferation of renal cell carcinoma by upregulating UPK1B.
Carcinoma, Renal Cell
Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma.
Carcinoma, Renal Cell
The circadian clock and the hypoxic response pathway in kidney cancer.
Carcinoma, Squamous Cell
Aberrant expression of clock gene period1 and its correlations with the growth, proliferation and metastasis of buccal squamous cell carcinoma.
Carcinoma, Squamous Cell
Altered expression of circadian clock genes in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.
Carcinoma, Squamous Cell
Circadian clock associates with tumor microenvironment in thoracic cancers.
Carcinoma, Squamous Cell
Circadian Clock Gene Bmal1 Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma.
Carcinoma, Squamous Cell
Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells.
Carcinoma, Squamous Cell
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Carcinoma, Squamous Cell
Epigenetic age acceleration of cervical squamous cell carcinoma converged to human papillomavirus 16/18 expression, immunoactivation, and favourable prognosis.
Carcinoma, Squamous Cell
Expression of p300 and p300/CBP associated factor (PCAF) in actinic keratosis and squamous cell carcinoma of the skin.
Carcinoma, Squamous Cell
Identification of the SOX2 interactome by BioID reveals EP300 as a mediator of SOX2-dependent squamous differentiation and lung squamous cell carcinoma growth.
Carcinoma, Squamous Cell
N-acetyltransferase 2 gene polymorphism in patients with cervical cancer.
Carcinoma, Squamous Cell
N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski).
Carcinoma, Squamous Cell
Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells.
Carcinoma, Squamous Cell
PER1 and CLOCK are potential circulating biomarkers for head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils.
Carcinoma, Squamous Cell
Research on circadian clock genes in non-small-cell lung carcinoma.
Carcinoma, Squamous Cell
Seeking the driver in tumours with apparent normal molecular profile on comparative genomic hybridization and targeted gene panel sequencing: what is the added value of whole exome sequencing?
Carcinoma, Squamous Cell
The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
Carcinoma, Squamous Cell
[Effect and Regulatory Mechanism of Clock Gene Per1 on Biological Behaviors of Human Oral Squamous Carcinoma Cell].
Cardiomegaly
Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats.
Cardiomegaly
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Cardiomegaly
Functional Analysis of GATA4 Complex, a Cardiac Hypertrophy-response Transcriptional Factor, Using a Proteomics Approach.
Cardiomegaly
Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice.
Cardiomegaly
Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.
Cardiomegaly
The histone acetyltransferase MOF overexpression blunts cardiac hypertrophy by targeting ROS in mice.
Cardiomegaly
The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity.
Cardiomyopathies
A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
Cardiomyopathies
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Cardiomyopathies
Female Clock?19/?19 Mice are Protected from the Development of Age-Dependent Cardiomyopathy.
Cardiomyopathies
N?-lysine acetylation determines dissociation from GAP junctions and lateralization of connexin 43 in normal and dystrophic heart.
Cardiomyopathy, Dilated
Cardiomyocyte-specific Bmal1 deletion in mice triggers diastolic dysfunction, extracellular matrix response, and impaired resolution of inflammation.
Cardiomyopathy, Hypertrophic
A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy.
Cardiotoxicity
Circadian Cyp3a11 metabolism contributes to chronotoxicity of hypaconitine in mice.
Cardiotoxicity
The circadian clock protects against ionizing radiation-induced cardiotoxicity.
Cardiovascular Diseases
A molecular clock regulates angiopoietin-like protein 2 expression.
Cardiovascular Diseases
A Mouse Primary Hepatocyte Culture Model for Studies of Circadian Oscillation.
Cardiovascular Diseases
A Review of Data of Findings on Night Shift Work and the Development of DM and CVD Events: a Synthesis of the Proposed Molecular Mechanisms.
Cardiovascular Diseases
Acetylation in cardiovascular diseases: Molecular mechanisms and clinical implications.
Cardiovascular Diseases
Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis.
Cardiovascular Diseases
Alterations of circadian expressions of clock genes in Dahl salt-sensitive rats fed a high-salt diet.
Cardiovascular Diseases
Anticipating anticipation: pursuing identification of cardiomyocyte circadian clock function.
Cardiovascular Diseases
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
Cardiovascular Diseases
Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
Cardiovascular Diseases
Bmal1 Downregulation Worsens Critical Limb Ischemia by Promoting Inflammation and Impairing Angiogenesis.
Cardiovascular Diseases
Cardiovascular disease, chronopharmacotherapy, and the molecular clock.
Cardiovascular Diseases
Cardiovascular diseases: a therapeutic perspective around the clock.
Cardiovascular Diseases
Circadian clock genes: Non-circadian roles in sleep, addiction, and psychiatric disorders?
Cardiovascular Diseases
Circadian Dysregulation: The Next Frontier in Obstructive Sleep Apnea Research.
Cardiovascular Diseases
Circadian Rhythm in Adipose Tissue: Novel Antioxidant Target for Metabolic and Cardiovascular Diseases.
Cardiovascular Diseases
Circadian Rhythm: Potential Therapeutic Target for Atherosclerosis and Thrombosis.
Cardiovascular Diseases
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.
Cardiovascular Diseases
Circadian rhythms in the CNS and peripheral clock disorders: role of the biological clock in cardiovascular diseases.
Cardiovascular Diseases
CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial.
Cardiovascular Diseases
Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and shifted the circadian oscillation of the hepatic clock and lipid metabolism-related genes in rats fed a high-fat diet.
Cardiovascular Diseases
Deoxycorticosterone/Salt-Mediated Cardiac Inflammation and Fibrosis Are Dependent on Functional CLOCK Signaling in Male Mice.
Cardiovascular Diseases
Diabetes and cardiovascular disease: related disorders created by disturbances in the endogenous clock.
Cardiovascular Diseases
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Cardiovascular Diseases
Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases.
Cardiovascular Diseases
Exploitation of host clock gene machinery by hepatitis viruses B and C.
Cardiovascular Diseases
Exploring the Relationship of Relative Telomere Length and the Epigenetic Clock in the LipidCardio Cohort.
Cardiovascular Diseases
G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review].
Cardiovascular Diseases
Identification of epigenetic factor KAT2B gene variants for possible roles in congenital heart diseases.
Cardiovascular Diseases
Influence of the cardiomyocyte circadian clock on cardiac physiology and pathophysiology.
Cardiovascular Diseases
Interactions between the circadian clock and metabolism: there are good times and bad times.
Cardiovascular Diseases
Lysine acetyltransferases and lysine deacetylases as targets for cardiovascular disease.
Cardiovascular Diseases
Methods for monitoring the functional status of the circadian system in dietary surveys studies: application criteria and interpretation of results.
Cardiovascular Diseases
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
Cardiovascular Diseases
Novel insights from genetic and molecular characterization of the human clock.
Cardiovascular Diseases
Old and New Roles and Evolving Complexities of Cardiovascular Clocks.
Cardiovascular Diseases
Period 2 is essential to maintain early endothelial progenitor cell function in vitro and angiogenesis after myocardial infarction in mice.
Cardiovascular Diseases
Period3 VNTR polymorphism influences the time-of-day pain onset of acute myocardial infarction with ST elevation.
Cardiovascular Diseases
Recent Advances in the Development of CBP/p300 Bromodomain Inhibitors.
Cardiovascular Diseases
Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury.
Cardiovascular Diseases
Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.
Cardiovascular Diseases
Sex Differences in the Impact of Shift Work Schedules on Pathological Outcomes in an Animal Model of Ischemic Stroke.
Cardiovascular Diseases
Shift work modifies the circadian patterns of heart rate variability in nurses.
Cardiovascular Diseases
Social class and all-cause mortality in an urban population of North India.
Cardiovascular Diseases
Targeting circadian PER2 as therapy in myocardial ischemia and reperfusion injury.
Cardiovascular Diseases
The Framingham Study, diabetes mellitus and cardiovascular disease: turning back the clock.
Cardiovascular Diseases
The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis.
Cardiovascular Diseases
The mammalian circadian clock and its entrainment by stress and exercise.
Cardiovascular Diseases
The role of clock genes and circadian rhythm in the development of cardiovascular diseases.
Cardiovascular Diseases
The suprachiasmatic nucleus is part of a neural feedback circuit adapting blood pressure response.
Cardiovascular Diseases
Thrombomodulin is a clock-controlled gene in vascular endothelial cells.
Cardiovascular Diseases
[Circadian CLOCK Gene Variants, Parameters of Arterial Stiffness and Blood Pressure Levels in Subjects Without Arterial Hypertension].
Cardiovascular Diseases
[Research advances in relationship between biological clock and cardiovascular diseases].
Carotid Stenosis
CLOCK disruption aggravates carotid artery stenosis through endoplasmic reticulum stress-induced endothelial-mesenchymal transition.
Carotid Stenosis
Loss of CLOCK under high glucose upregulates ROCK1-mediated endothelial to mesenchymal transition and aggravates plaque vulnerability.
Cartilage Diseases
Clock Gene Bmal1 Modulates Human Cartilage Gene Expression by Crosstalk With Sirt1.
Cataract
A cataract, 'a million cut' radial keratotomy, and Marfan syndrome February consultation #1.
Cataract
Cataract in infants treated with argon laser photocoagulation for threshold retinopathy of prematurity.
Cataract
Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice.
Cataract
Effectiveness and safety of combined cataract surgery and microhook ab interno trabeculotomy in Japanese eyes with glaucoma: report of an initial case series.
Cataract
Femtosecond laser-assisted successful management of subluxated cataractous lens with vitreous in anterior chamber.
Cataract
Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract.
Cataract
Management of Severely Subluxated Cataracts Using Femtosecond Laser-Assisted Cataract Surgery.
Cataract
N-acetyltransferase 2 phenotype may be associated with susceptibility to age-related cataract.
Cataract
Pneumatic retinopexy: a survey of current practice patterns among the vitreous society members.
Catatonia
Refractory Catatonia Due to N-methyl-D-Aspartate Receptor Encephalitis Responsive to Electroconvulsive Therapy: The Clinical Use of the Clock Drawing Test.
Central Nervous System Diseases
Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells.
Cerebellar Ataxia
Psychometric properties of clock and pelvic drawings in Parkinson's disease: A validity and cross-sectional study.
Cerebral Hemorrhage
Race against the clock: overcoming challenges in the management of anticoagulant-associated intracerebral hemorrhage.
Cerebral Small Vessel Diseases
Assessing Performance on Digital Clock Drawing Test in Aged Patients With Cerebral Small Vessel Disease.
Cerebrovascular Disorders
Diagnostic Performance of Clock Drawing Test by CLOX in an Asian Chinese population.
Cerebrovascular Disorders
The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea.
Chagas Disease
Clock Gene Timeless in the Chagas Disease Vector Triatoma infestans (Hemiptera: Reduviidae).
Chagas Disease
Nuclear rDNA-based molecular clock of the evolution of triatominae (Hemiptera: reduviidae), vectors of Chagas disease.
Chagas Disease
Phylogenetic multilocus codon models and molecular clocks reveal the monophyly of haematophagous reduviid bugs and their evolution at the formation of South America.
Chemical and Drug Induced Liver Injury
Association of genetic polymorphisms of CYP2E1, NAT2, GST and SLCO1B1 with the risk of anti-tuberculosis drug-induced liver injury: a systematic review and meta-analysis.
Chemical and Drug Induced Liver Injury
Genetic and ethnic risk factors associated with drug hypersensitivity.
Chemical and Drug Induced Liver Injury
N-acetyltransferase 2 (NAT2) genotype as a risk factor for development of drug-induced liver injury relating to antituberculosis drug treatment in a mixed-ethnicity patient group.
Chemical and Drug Induced Liver Injury
NAT2 polymorphisms and susceptibility to anti-tuberculosis drug-induced liver injury: a meta-analysis.
Chemical and Drug Induced Liver Injury
Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis.
Chemical and Drug Induced Liver Injury
Susceptibility of N-acetyltransferase 2 slow acetylators to antituberculosis drug-induced liver injury: a meta-analysis.
Chickenpox
Rubinstein-Taybi syndrome and CREBBP c.201 202delTA mutation: a case presenting with varicella meningoencephalitis.
Chlamydia Infections
Effect of Time of Day of Infection on Chlamydia Infectivity and Pathogenesis.
Cholangiocarcinoma
Intrahepatic cholangiocarcinoma after Fontan procedure in an adult with visceral heterotaxy.
Cholangiocarcinoma
miR-34a-dependent overexpression of Per1 decreases cholangiocarcinoma growth.
Cholangiocarcinoma
Thyroid-Like Cholangiocarcinoma: Histopathological, Immunohistochemical, In-Situ Hybridization and Molecular Studies on an Uncommon Emerging Entity.
Cholangiocarcinoma
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Cholangitis
Are primary biliary cirrhosis and autoimmune cholangitis reflective of the pendulum of a clock and therefore represent a 'phase' of the same disease?
Cholera
A recalibrated molecular clock and independent origins for the cholera pandemic clones.
Cholera
Alpha 2-adrenergic regulation of arylalkylamine N-acetyltransferase in organ-cultured chick pineal gland: characterization with agonists and modulation of experimentally stimulated enzyme activity.
Cholera
Arginine Vasopressin-Containing Neurons of the Suprachiasmatic Nucleus Project to CSF.
Cholestasis
Deletion of clock gene Per2 exacerbates cholestatic liver injury and fibrosis in mice.
Cholestasis, Intrahepatic
Nuclear receptors, gestational metabolism and maternal metabolic disorders.
Chondrosarcoma
Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.
Choroidal Effusions
Cyclodialysis ab interno as a surgical approach to intractable glaucoma.
Choroidal Effusions
Time to Unplanned Return to the Operating Room and Associated Risk Factors in Patients With Surgical Retinal Detachment Repair.
Chronic Kidney Disease-Mineral and Bone Disorder
Circadian rhythms of mineral metabolism in chronic kidney disease-mineral bone disorder.
Chronic Periodontitis
Knock-on effect of periodontitis to the pathogenesis of Alzheimer's disease?
Chronobiology Disorders
A randomized, double-blind and placebo-controlled crossover trial on the effect of l-ornithine ingestion on the human circadian clock.
Chronobiology Disorders
An impaired hepatic clock system effects lipid metabolism in rats with nephropathy.
Chronobiology Disorders
Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock.
Chronobiology Disorders
Circadian disruption in cancer: a neuroendocrine-immune pathway from stress to disease?
Chronobiology Disorders
Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder.
Chronobiology Disorders
Circadian Dysregulation: The Next Frontier in Obstructive Sleep Apnea Research.
Chronobiology Disorders
D-Ser2-oxyntomodulin ameliorated A?31-35-induced circadian rhythm disorder in mice.
Chronobiology Disorders
Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind.
Chronobiology Disorders
Disruption of behavioral circadian rhythms induced by psychophysiological stress affects plasma free amino acid profiles without affecting peripheral clock gene expression in mice.
Chronobiology Disorders
Hydrogen peroxide modulates clock gene expression via PRX2-STAT3-REV-ERB?/? pathway.
Chronobiology Disorders
Modulatory effect of Cyclocarya paliurus flavonoids on the intestinal microbiota and liver clock genes of circadian rhythm disorder mice model.
Chronobiology Disorders
Molecular clock integration of brown adipose tissue formation and function.
Chronobiology Disorders
Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance.
Chronobiology Disorders
Non-invasive 40-Hz Light Flicker Ameliorates Alzheimer's-Associated Rhythm Disorder via Regulating Central Circadian Clock in Mice.
Chronobiology Disorders
Recent advances in modulators of circadian rhythms: an update and perspective.
Chronobiology Disorders
The ticking clock of Cayo Santiago macaques and its implications for understanding human circadian rhythm disorders.
Chronobiology Disorders
[A role of nociceptin in the entrainment mechanism of the biological clock]
Chronobiology Disorders
[Physiology of the biological clock and the relation of circadian rhythm disorders to illnesses]
Classical Swine Fever
Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.
Cleft Lip
Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts.
Cleft Palate
Confirmation of the role of N-acetyltransferase 2 in teratogen-induced cleft palate using transgenics and knockouts.
Cleft Palate
NTN1 gene was risk to non-syndromic cleft lip only among Han Chinese population.
Cluster Headache
A chronobiological study of melatonin, cortisol growth hormone and prolactin secretion in cluster headache.
Cluster Headache
A genetic CLOCK variant associated with cluster headache causing increased mRNA levels.
Cluster Headache
Cluster headache: evidence for a disorder of circadian rhythm and hypothalamic function.
Cluster Headache
Emerging relevance of circadian rhythms in headaches and neuropathic pain.
Cluster Headache
Genetic association of HCRTR2, ADH4 and CLOCK genes with cluster headache: a Chinese population-based case-control study.
Cluster Headache
Lack of association between cluster headache and PER3 clock gene polymorphism.
Cluster Headache
Lack of association between the 3092 T-->C Clock gene polymorphism and cluster headache.
Cluster Headache
Melatonin as adjunctive therapy in the prophylaxis of cluster headache: a pilot study.
Cluster Headache
Opioidergic changes in the pineal gland and hypothalamus in cluster headache: a ligand PET study.
Cluster Headache
The molecular clock gene cryptochrome 1 (CRY1) and its role in cluster headache.
Coinfection
Occurrence and reassortment of avian influenza A (H7N9) viruses derived from coinfected birds in China.
Colitis
Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer.
Colitis
Circadian pharmacological effects of berberine on chronic colitis in mice: Role of the clock component Rev-erb?.
Colitis
REV-ERB? integrates colon clock with experimental colitis through regulation of NF-?B/NLRP3 axis.
Colitis
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Colitis, Ulcerative
An Inhibitor of Casein Kinase 1?/? (PF670462) Prevents the Deterioration of Dextran Sodium Sulfate-induced Ulcerative Colitis Caused by UVB Eye Irradiation.
Colitis, Ulcerative
Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans.
Colitis, Ulcerative
Complex changes of circadian proteins expression in inflammatory bowel disease.
Colitis, Ulcerative
Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.
Colitis, Ulcerative
Importance of the Evaluation of N-Acetyltransferase Enzyme Activity Prior to 5-Aminosalicylic Acid Medication for Ulcerative Colitis.
Colitis, Ulcerative
N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis.
Colitis-Associated Neoplasms
Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer.
Coloboma
Combination of capsular tension ring and capsular tension segment for the management of lens coloboma >4 clock hours.
Coloboma
Exome Sequencing Identification of EP300 Mutation in a Proband with Coloboma and Imperforate Anus: Possible Expansion of the Phenotypic Spectrum of Rubinstein-Taybi Syndrome.
Colonic Neoplasms
A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion.
Colonic Neoplasms
Arylamine N-acetyltransferase: a possible promoter in Helicobacter pylori-related gastric carcinogenesis.
Colonic Neoplasms
Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.
Colonic Neoplasms
Circadian clock gene Period2 suppresses human chronic myeloid leukemia cell proliferation.
Colonic Neoplasms
Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters.
Colonic Neoplasms
Circadian rhythm of transferrin receptor 1 gene expression controlled by c-Myc in colon cancer-bearing mice.
Colonic Neoplasms
Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer.
Colonic Neoplasms
Genetic disruption of tubulin acetyltransferase, ?TAT1, inhibits proliferation and invasion of colon cancer cells through decreases in Wnt1/?-catenin signaling.
Colonic Neoplasms
Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs.
Colonic Neoplasms
Hypermethylation of N-Acetyltransferase 1 Is a Prognostic Biomarker in Colon Adenocarcinoma.
Colonic Neoplasms
Inhibition of N-acetyltransferase activity and gene expression in human colon cancer cell lines by diallyl sulfide.
Colonic Neoplasms
Inhibition of Wnt/?-Catenin pathway and Histone acetyltransferase activity by Rimonabant: a therapeutic target for colon cancer.
Colonic Neoplasms
Interplay between heterocyclic amines in cooked meat and metabolic phenotype in the etiology of colon cancer.
Colonic Neoplasms
microRNA-342-5p and miR-608 inhibit colon cancer tumorigenesis by targeting NAA10.
Colonic Neoplasms
Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic study.
Colonic Neoplasms
N-Acetyltransferase 2 and glutathione s-transferase M1 in colon and rectal cancer cases from an industrialized area.
Colonic Neoplasms
OVEREXPRESSION OF BOTH CLOCK AND BMAL1 INHIBITS ENTRY TO S PHASE IN HUMAN COLON CANCER CELLS.
Colonic Neoplasms
Overexpression of histone deacetylases in cancer cells is controlled by interplay of transcription factors and epigenetic modulators.
Colonic Neoplasms
Peptide mimic isolated by autoantibody reveals human arrest defective 1 overexpression is associated with poor prognosis for colon cancer patients.
Colonic Neoplasms
Polymorphic N-acetylation of 2-aminofluorene by cell-free colon extracts from inbred mice.
Colonic Neoplasms
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Colonic Neoplasms
Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors.
Colonic Neoplasms
Shiftwork-Mediated Disruptions of Circadian Rhythms and Sleep Homeostasis Cause Serious Health Problems.
Colonic Neoplasms
Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP4 receptors and their mediation of cyclooxygenase-2 induction in HCA-7 human colon cancer cells.
Colonic Neoplasms
The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.
Colonic Neoplasms
The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer.
Colonic Neoplasms
The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock and Enhances Malignant Phenotypes.
Colonic Neoplasms
XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Colorectal Neoplasms
5-Fluorouracil targets histone acetyltransferases p300/CBP in the treatment of colorectal cancer.
Colorectal Neoplasms
A meta-analysis of the relationship between NAT2 polymorphism and colorectal cancer susceptibility.
Colorectal Neoplasms
A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer.
Colorectal Neoplasms
Absence of Association between N-Acetyltransferase 2 Acetylator Status and Colorectal Cancer Susceptibility: Based on Evidence from 40 Studies.
Colorectal Neoplasms
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9.
Colorectal Neoplasms
Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes.
Colorectal Neoplasms
Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.
Colorectal Neoplasms
Alteration of microRNA-4474/4717 expression and CREB-binding protein in human colorectal cancer tissues infected with Fusobacterium nucleatum.
Colorectal Neoplasms
An association between clock genes and clock-controlled cell cycle genes in murine colorectal tumors.
Colorectal Neoplasms
Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer.
Colorectal Neoplasms
Analysis of the Circadian Regulation of Cancer Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington's Disease.
Colorectal Neoplasms
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking.
Colorectal Neoplasms
Association of Epigenetic Clock with Consensus Molecular Subtypes and Overall Survival of Colorectal Cancer.
Colorectal Neoplasms
Association of the clock genes polymorphisms with colorectal cancer susceptibility.
Colorectal Neoplasms
Bayesian analysis on meta-analysis of case-control studies accounting for within-study correlation.
Colorectal Neoplasms
BRD8, which is negatively regulated by miR-876-3p, promotes the proliferation and apoptosis resistance of hepatocellular carcinoma cells via KAT5.
Colorectal Neoplasms
C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer.
Colorectal Neoplasms
Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.
Colorectal Neoplasms
Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.
Colorectal Neoplasms
Circadian clock pathway genes associated with colorectal cancer risk and prognosis.
Colorectal Neoplasms
Circadian gene hCLOCK contributes to progression of colorectal carcinoma and is directly regulated by tumor?suppressive microRNA?124.
Colorectal Neoplasms
Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.
Colorectal Neoplasms
Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney.
Colorectal Neoplasms
Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk.
Colorectal Neoplasms
Core Circadian Clock Proteins as Biomarkers of Progression in Colorectal Cancer.
Colorectal Neoplasms
Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer.
Colorectal Neoplasms
CREB-binding protein, p300, butyrate, and Wnt signaling in colorectal cancer.
Colorectal Neoplasms
Deregulation of the circadian clock machinery: A novel biomarker for anti-angiogenic drug resistance in colorectal cancer.
Colorectal Neoplasms
Disruption of clock gene expression in human colorectal liver metastases.
Colorectal Neoplasms
Down-regulation of Tip60 gene as a potential marker for the malignancy of colorectal cancer.
Colorectal Neoplasms
Effects of aging and tumorigenesis on coupling between the circadian clock and cell cycle in colonic mucosa.
Colorectal Neoplasms
Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.
Colorectal Neoplasms
Expression of circadian clock gene human Period2 (hPer2) in human colorectal carcinoma.
Colorectal Neoplasms
Expression of Circadian Clock Genes in Human Colorectal Cancer Tissues Using Droplet Digital PCR.
Colorectal Neoplasms
Expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates with location of tumor differently.
Colorectal Neoplasms
Expression of core clock genes in colorectal tumour cells compared with normal mucosa; a systematic review of clinical trials.
Colorectal Neoplasms
Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression.
Colorectal Neoplasms
Expression of PER, CRY, and TIM genes for the pathological features of colorectal cancer patients.
Colorectal Neoplasms
Expression of the EP300, TP53 and BAX genes in colorectal cancer: Correlations with clinicopathological parameters and survival.
Colorectal Neoplasms
Expressional and Mutational Analysis of CREBBP Gene in Gastric and Colorectal Cancers with Microsatellite Instability.
Colorectal Neoplasms
Frameshift mutations of tumor suppressor gene EP300 in gastric and colorectal cancers with high microsatellite instability.
Colorectal Neoplasms
Genetic polymorphisms of N-acetyltransferase 2 and colorectal cancer risk.
Colorectal Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Colorectal Neoplasms
Glutathione S-transferase (GST) M1, T1, P1, N-acetyltransferase (NAT) 1 and 2 genetic polymorphisms and susceptibility to colorectal cancer.
Colorectal Neoplasms
GSK-3?-Regulated N-Acetyltransferase 10 Is Involved in Colorectal Cancer Invasion.
Colorectal Neoplasms
Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT.
Colorectal Neoplasms
Identification and meta-analysis of copy number variation-driven circadian clock genes for colorectal cancer.
Colorectal Neoplasms
Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer.
Colorectal Neoplasms
Lack of association between the polyadenylation polymorphism in the NAT1 (acetyltransferase 1) gene and colorectal adenomas.
Colorectal Neoplasms
MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
Colorectal Neoplasms
Marker rhythms of circadian system function: a study of patients with metastatic colorectal cancer and good performance status.
Colorectal Neoplasms
Meta-analysis of 20 case-control studies on the N-acetyltransferase 2 acetylation status and colorectal cancer risk.
Colorectal Neoplasms
Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
Colorectal Neoplasms
N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).
Colorectal Neoplasms
N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer.
Colorectal Neoplasms
N-Acetyltransferase 10 Promotes Micronuclei Formation to Activate the Senescence-Associated Secretory Phenotype Machinery in Colorectal Cancer Cells.
Colorectal Neoplasms
N-acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: risk variability according to tumour site?
Colorectal Neoplasms
N-acetyltransferase 2 gene polymorphism in patients with colorectal carcinoma.
Colorectal Neoplasms
N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer.
Colorectal Neoplasms
N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions.
Colorectal Neoplasms
N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.
Colorectal Neoplasms
N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review.
Colorectal Neoplasms
NAT2 knockdown inhibits the development of colorectal cancer and its clinical significance.
Colorectal Neoplasms
No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Colorectal Neoplasms
Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and ?-Catenin Signaling.
Colorectal Neoplasms
Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer.
Colorectal Neoplasms
Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer.
Colorectal Neoplasms
Patient clock drawing and accuracy of self-report compared with chart review for colorectal cancer (CRC) screening.
Colorectal Neoplasms
PCR and flow cytometric analysis of paclitaxel-inhibited arylamine N-acetyltransferase activity and gene expression in human osteogenic sarcoma cells (U-2 OS).
Colorectal Neoplasms
Polymorphic N-acetylation of 2-aminofluorene by cell-free colon extracts from inbred mice.
Colorectal Neoplasms
Polymorphisms of cytochrome P450 1A2 and N-acetyltransferase genes, meat consumption, and risk of colorectal cancer.
Colorectal Neoplasms
Prognosis model of colorectal cancer patients based on NOTCH3, KMT2C, and CREBBP mutations.
Colorectal Neoplasms
Rapid N-acetyltransferase 2 imputed phenotype and smoking may increase risk of colorectal cancer in women (Netherlands).
Colorectal Neoplasms
Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors.
Colorectal Neoplasms
Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.
Colorectal Neoplasms
Relationship between acetylator status, smoking, and diet and colorectal cancer risk in the north-east of England.
Colorectal Neoplasms
Relationship between metabolic enzyme polymorphism and colorectal cancer.
Colorectal Neoplasms
Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population.
Colorectal Neoplasms
Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer.
Colorectal Neoplasms
Sex-dependent least toxic timing of irinotecan combined with chronomodulated chemotherapy for metastatic colorectal cancer: Randomized multicenter EORTC 05011 trial.
Colorectal Neoplasms
Sex-dependent regulation of estrogen receptor beta in human colorectal cancer tissue and its relationship with clock genes and VEGF-A expression.
Colorectal Neoplasms
Targeting tumor vulnerabilities associated with loss of heterozygosity.
Colorectal Neoplasms
The association of NAT1 polymorphisms and colorectal carcinoma risk: evidence from 20,000 subjects.
Colorectal Neoplasms
The circadian clock gene, Bmal1, regulates intestinal stem cell signaling and represses tumor initiation.
Colorectal Neoplasms
The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.
Colorectal Neoplasms
The CYP1A2-164A-->C polymorphism (CYP1A2*1F) is associated with the risk for colorectal adenomas in humans.
Colorectal Neoplasms
The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock and Enhances Malignant Phenotypes.
Colorectal Neoplasms
The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways.
Colorectal Neoplasms
USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3.
Colorectal Neoplasms
Western diet, family history of colorectal cancer, NAT2, GSTM-1 and risk of colon cancer.
Colorectal Neoplasms, Hereditary Nonpolyposis
Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors.
Colorectal Neoplasms, Hereditary Nonpolyposis
N-acetyltransferase (NAT) 2 acetylator status and age of onset in patients with hereditary nonpolyposis colorectal cancer (HNPCC).
Coma
Cerebral perfusion alterations and cognitive decline in critically ill sepsis survivors.
Coma
Detecting delirium in patients with acute stroke: a systematic review of test accuracy.
Coma
Is the Glasgow Coma Scale Score in Children in the Emergency Department Lower During the Night?
Coma
[Circadian clock genes expression in peripheral blood mononuclear cells of comatose patients].
Communicable Diseases
For Whom the Clock Ticks: Clinical Chronobiology for Infectious Diseases.
Communicable Diseases
Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1.
Communication Disorders
Validation of the Greek version of the Abbreviated Mental Test Score: Preliminary findings for cognitively impaired patients of different etiology.
Confusion
Cerebral perfusion alterations and cognitive decline in critically ill sepsis survivors.
Confusion
How Many Clocks, How Many Times? On the Sensory Basis and Computational Challenges of Circadian Systems.
Confusion
The potential role of relatives in designing person-centred assistive technologies (innovative practice).
Confusion
Validity of the confusion assessment method in detecting postoperative delirium in the elderly.
Congenital Abnormalities
Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3' untranslated regions.
Congenital Abnormalities
Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1.
Congenital Abnormalities
Sex Differences in Patients With CAM Deformities With Femoroacetabular Impingement: 3-Dimensional Computed Tomographic Quantification.
Congenital Abnormalities
The vertebrate segmentation clock and its role in skeletal birth defects.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Molecular clocks underlying vertebrate embryo segmentation: A 10-year-old hairy-go-round.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Whole exome sequencing reveals de novo pathogenic variants in KAT6A as a cause of a neurodevelopmental disorder.
Connective Tissue Diseases
[Clinical evaluation of N-acetyltransferase activity in children with various forms of diffuse connective tissue diseases]
Corneal Edema
Rate and Localization of Graft Detachment in Descemet Membrane Endothelial Keratoplasty.
Corneal Neovascularization
Nature and incidence of severe limbal stem cell deficiency in Australia and New Zealand.
Corneal Neovascularization
Thalidomide prevents donor corneal graft neovascularization in an alkali burn model of corneal angiogenesis.
Corneal Neovascularization
[A synthetic peptide selected by bioinformatics inhibits mouse corneal neovascularization]
Corneal Ulcer
The successful treatment of a multidrug-resistant Achromobacter xylosoxidans corneal ulcer with topical meropenem.
Coronary Artery Disease
Does exercise training impact clock genes in patients with coronary artery disease and type 2 diabetes mellitus?
Coronary Artery Disease
[Association of T3111C polymorphism in 3'-untranslated region of the CLOCK gene with the risk of essential arterial hypertension and coronary artery disease in the Russian population Karelia].
Coronary Disease
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Coronary Disease
Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?
Coronary Disease
Chronic consumption of a low-fat diet improves cardiometabolic risk factors according to the CLOCK gene in patients with coronary heart disease.
Coronary Disease
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studies.
Cough
Circadian changes in effectiveness of corticosteroids in eight patients with allergic asthma.
COVID-19
An Early Pandemic Analysis of SARS-CoV-2 Population Structure and Dynamics in Arizona.
COVID-19
Circadian Clock Genes: Targeting Innate Immunity for Antiviral Strategies Against COVID-19.
COVID-19
Circadian clock modulating small molecules repurposing as inhibitors of SARS-CoV-2 Mpro for pharmacological interventions in COVID-19 pandemic.
COVID-19
Clock genes may drive seasonal variation in SARS-CoV-2 infectivity: are we due for a second wave of COVID-19 in the fall?
COVID-19
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
COVID-19
Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19.
COVID-19
Is There a Link between Orcadian Clock Protein PERIOD 3 (PER3) (rs57875989) Variant and the Severity of COVID-19 Infection?
COVID-19
Phylogenetic reconstruction of the initial stages of the spread of the SARS-CoV-2 virus in the Eurasian and American continents by analyzing genomic data.
COVID-19
Putative contributions of circadian clock and sleep in the context of SARS-CoV-2 infection.
COVID-19
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
COVID-19
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.
COVID-19
Strengths and Weaknesses of Docking Simulations in the SARS-CoV-2 Era: the Main Protease (Mpro) Case Study.
COVID-19
Telemedicine for Diabetes After the COVID-19 Pandemic: We Can't Put the Toothpaste Back in the Tube or Turn Back the Clock.
COVID-19
The case for chronotherapy in Covid-19-induced acute respiratory distress syndrome.
COVID-19
The Circadian Clock, the Brain, and COVID-19: The Cases of Olfaction and the Timing of Sleep.
COVID-19
Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1.
COVID-19
World Tuberculosis Day 2021 Theme - 'The Clock is Ticking' - and the world is running out of time to deliver the United Nations General Assembly commitments to End TB due to the COVID-19 pandemic.
Craniosynostoses
A Novel Frameshift Mutation in KAT6A Is Associated with Pancraniosynostosis.
Craniosynostoses
First case of pan-suture craniosynostosis due to de novo mosaic KAT6A mutation.
Craniosynostoses
Lin-Gettig syndrome: Craniosynostosis expands the spectrum of the KAT6B related disorders.
Crohn Disease
Characterization of genetic loci that affect susceptibility to inflammatory bowel diseases in African Americans.
Crohn Disease
Complex changes of circadian proteins expression in inflammatory bowel disease.
Crohn Disease
Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene.
Cushing Syndrome
A putative role for the aryl hydrocarbon receptor (AHR) gene in a patient with cyclical Cushing's disease.
Cushing Syndrome
Glucocorticoid-induced fingerprints on visceral adipose tissue transcriptome and epigenome.
Cushing Syndrome
MECHANISMS IN ENDOCRINOLOGY: A sense of time of the glucocorticoid circadian clock: from the ontogeny to the diagnosis of Cushing's syndrome.
Cyclodialysis Clefts
Direct cyclopexy for traumatic cyclodialysis with persisting hypotony. Report in 29 consecutive patients.
Cyclodialysis Clefts
Placement of dual capsular tension rings for the combined management of traumatic cyclodialysis cleft and zonular dialysis.
Cystic Fibrosis
Activities of cytochrome P450 1A2, N-acetyltransferase 2, xanthine oxidase, and cytochrome P450 2D6 are unaltered in children with cystic fibrosis.
Cystic Fibrosis
Assessment of arylamine N-acetyltransferase (NAT1) activity in mononuclear leukocytes of cystic fibrosis patients.
Cystic Fibrosis
Decreased histone deacetylase activity in chronic obstructive pulmonary disease.
Cystic Fibrosis
Detection of human DNA mutations with nonradioactive, allele-specific oligonucleotide probes.
Cystic Fibrosis
Interaction with CREB binding protein modulates the activities of Nrf2 and NF-?B in cystic fibrosis airway epithelial cells.
Cysts
CONTROL OF GERMINATION OF ALEXANDRIUM TAMARENSE (DINOPHYCEAE) CYSTS FROM THE LOWER ST. LAWRENCE ESTUARY (CANADA)
Cysts
The clock face guide to peroneal intraneural ganglia: critical "times" and sites for accurate diagnosis.
De Lange Syndrome
Exome sequencing identifies a novel EP300 frame shift mutation in a patient with features that overlap Cornelia de Lange syndrome.
De Lange Syndrome
Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome.
Deaf-Blind Disorders
Usability of assistive listening devices by older adults with low vision.
Death, Sudden, Cardiac
Circadian rhythm dynamics on multiscale entropy identifies autonomic dysfunction associated with risk of ventricular arrhythmias and near syncope in chronic kidney disease.
Death, Sudden, Cardiac
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Dehydration
Biomimetic alcohol oxidations by an iron(III) porphyrin complex: relevance to cytochrome P-450 catalytic oxidation and involvement of the two-state radical rebound mechanism.
Dehydration
Extensive Transcriptome Changes During Natural Onset and Release of Vegetative Bud Dormancy in Populus.
Dehydration
Genome wide transcriptional profiling of acclimation to photoperiod in high-latitude accessions of Arabidopsis thaliana
Dehydration
Genome wide transcriptional profiling of acclimation to photoperiod in high-latitude accessions of Arabidopsis thaliana.
Dehydration
Interplay between circadian rhythm, time of the day and osmotic stress constraints in the regulation of the expression of a Solanum Double B-box gene.
Dehydration
The root-colonizing endophyte Pirifomospora indica confers drought tolerance in Arabidopsis by stimulating the expression of drought stress-related genes in leaves.
Delirium
A novel digital clock drawing test as a screening tool for perioperative neurocognitive disorders: A feasibility study.
Delirium
A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients.
Delirium
Abnormal Sleep, Circadian Rhythm Disruption, and Delirium in the ICU: Are They Related?
Delirium
Attention, vigilance and visuospatial function in hospitalized elderly medical patients: Relationship to neurocognitive diagnosis.
Delirium
Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery.
Delirium
Disruption of Circadian Rhythms and Delirium, Sleep Impairment and Sepsis in Critically ill Patients. Potential Therapeutic Implications for Increased Light-Dark Contrast and Melatonin Therapy in an ICU Environment.
Delirium
Functional connectivity of the circadian clock and neural substrates of sleep-wake disturbance in delirium.
Delirium
Incidence and risk factors of acute delirium in older patients with hip fracture in Siriraj Hospital.
Delirium
Preoperative risk factors for postoperative delirium (POD) after urological surgery in the elderly.
Delirium
Preoperative risk factors of postoperative delirium after transurethral prostatectomy for benign prostatic hyperplasia.
Delirium
Prevalence and risk factors of postoperative delirium in patients undergoing open heart surgery in northwest of iran.
Delirium
Prevalence of delirium among patients at a cancer ward: Clinical risk factors and prediction by bedside cognitive tests.
Delirium
Rivastigmine for the prevention of postoperative delirium in elderly patients undergoing elective cardiac surgery--a randomized controlled trial.
Delirium
The clock drawing test is a poor screening tool for postoperative delirium and cognitive dysfunction after aortic repair.
Delirium
The performance of the Clock Drawing Test in elderly medical inpatients: does it have utility in the identification of delirium?
Delirium
The utility of the clock drawing test in detection of delirium in elderly hospitalised patients.
Delirium
The utility of the ten-point clock test as a screen for cognitive impairment in general hospital patients.
Delirium
Underdiagnosis of delirium on admission and prediction of patients who will develop delirium during their inpatient stay: a pilot study.
Delirium
Validity of the confusion assessment method in detecting postoperative delirium in the elderly.
Delirium
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
Dementia
2 clock tests had high accuracy and naïve raters had acceptable accuracy for detecting dementia.
Dementia
A comparison of five clock scoring methods using ROC (receiver operating characteristic) curve analysis.
Dementia
A longitudinal follow-up of 550 mild cognitive impairment patients: evidence for large conversion to dementia rates and detection of major risk factors involved.
Dementia
A new approach for the quantitative evaluation of the clock drawing test: preliminary results on subjects with Parkinson's disease.
Dementia
A quick test of cognitive speed (AQT): usefulness in dementia evaluations in primary care.
Dementia
A randomised controlled trial testing the impact of exercise on cognitive symptoms and disability of residents with dementia.
Dementia
A reduced scoring system for the Clock Drawing Test using a population-based sample.
Dementia
A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans.
Dementia
Accuracy of the clock drawing test for detecting dementia in a multicultural sample of elderly Australian patients.
Dementia
Altered temporal patterns of anxiety in aged and amyloid precursor protein (APP) transgenic mice.
Dementia
An analysis of the cognitive items of the movement disorders society checklist for the diagnosis of dementia in patients with Parkinson's disease.
Dementia
An Artificial Intelligence-Assisted Method for Dementia Detection Using Images from the Clock Drawing Test.
Dementia
Are our norms "normal"? A 4-year follow-up study of a biracial sample of rural elders with low education.
Dementia
Assessment of Dementia in Individuals with Dual Sensory Loss: Application of a Tactile Test Battery.
Dementia
Association of the Qualitative Clock Drawing Test with Progression to Dementia in Non-Demented Older Adults.
Dementia
Attention, vigilance and visuospatial function in hospitalized elderly medical patients: Relationship to neurocognitive diagnosis.
Dementia
Brain structural and cognitive correlates of clock drawing performance in Alzheimer's disease.
Dementia
Brief Tests such as the Clock Drawing Test or Cognistat Can Be Useful Predictors of Conversion from MCI to Dementia in the Clinical Assessment of Outpatients.
Dementia
Broad spectrum assessment of psychopathology and adaptive functioning with the Older Adult Behavior Checklist: a validation and diagnostic discrimination study.
Dementia
Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study.
Dementia
Characteristics of clock drawing test (CDT) errors by the dementia type: quantitative and qualitative analyses.
Dementia
Characteristics of patients assessed for cognitive decline in primary healthcare, compared to patients assessed in specialist healthcare.
Dementia
Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test.
Dementia
Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment.
Dementia
Clock drawing as a screen for impaired driving in aging and dementia: is it worth the time?
Dementia
Clock drawing errors in dementia: neuropsychological and neuroanatomical considerations.
Dementia
Clock Drawing in the Montreal Cognitive Assessment: Recommendations for Dementia Assessment.
Dementia
Clock drawing test (CDT) and activities of daily living (ADL) questionnaire as a short screening test for dementia in Thai population.
Dementia
Clock Drawing Test - screening utility for mild cognitive impairment according to different scoring systems: results of the Leipzig Longitudinal Study of the Aged (LEILA 75+).
Dementia
Clock Drawing Test in acute stroke and its relationship with long-term functional and cognitive outcomes.
Dementia
Clock drawing test in elderly individuals with different education levels: correlation with clinical dementia rating.
Dementia
Clock drawing test in mild and moderate dementia of the Alzheimer's type: a comparative and correlation study.
Dementia
Clock drawing test in mild cognitive impairment: quantitative analysis of four scoring methods and qualitative analysis.
Dementia
Clock drawing test in screening for Alzheimer's dementia and mild cognitive impairment in clinical practice.
Dementia
Clock drawing test ratings by dementia specialists: interrater reliability and diagnostic accuracy.
Dementia
Clock Drawing Test-Modified and Integrated Approach (CDT-MIA): description and preliminary examination of its validity and reliability in dementia patients referred to a specialized psychogeriatric setting.
Dementia
Clock Drawing Test: A Simple Scoring System for the Accurate Screening of Cognitive Impairment in Patients with Mild Cognitive Impairment and Dementia.
Dementia
Clock drawing test: correlation with linear measurements of CT studies in demented patients.
Dementia
Clock drawing test: is it useful for dementia screening in patients having Parkinson disease with and without depression?
Dementia
Clock drawing, clock reading, clock setting, and judgment of clock faces in elderly people with dementia and depression.
Dementia
Clock Test Deficits Related to the Global Cognitive State in Alzheimer's and Parkinson's Disease.
Dementia
Cluster analysis of cognitive performance in a sample of patients with Parkinson's disease.
Dementia
Codex (Cognitive Disorders Examination) Decision Tree Modified for the Detection of Dementia and MCI.
Dementia
Cognitive Functions across the GNB3 C825T Polymorphism in an Elderly Italian Population.
Dementia
Cognitive Impairment and Dementia: Gaining Insight through Circadian Clock Gene Pathways.
Dementia
Cognitive impairment in 873 patients with idiopathic Parkinson's disease. Results from the German Study on Epidemiology of Parkinson's Disease with Dementia (GEPAD).
Dementia
Cognitive screening in Parkinson's disease: Comparison of the Parkinson Neuropsychometric Dementia Assessment (PANDA) with 3 other short scales.
Dementia
Cognitive Screening Tool for Geriatrics: A Retrospective Observational Study on the Correlation of the Scores in 30-Point Clock Face Test and MMSE.
Dementia
Cognitive stimulation for older people with Alzheimer's disease performed by the caregiver.
Dementia
Combination of the Clock Drawing Test with the Physical Phenotype of Frailty for the Prediction of Mortality and Other Adverse Outcomes in Older Community Dwellers without Dementia.
Dementia
Comparing clock tests for dementia screening: naïve judgments vs formal systems--what is optimal?
Dementia
Comparison of the clock test and a questionnaire-based test for screening for cognitive impairment in Nigerians.
Dementia
Comparisons of cognitive function and serum S-100B level between diabetic and non-diabetic patients after the implantation of carotid artery stent (CAS).
Dementia
Computer-Based Driving in Dementia Decision Tool With Mail Support: Cluster Randomized Controlled Trial.
Dementia
Correlation of MMSE, SKT and clock test scores in patients with mild and moderate dementia.
Dementia
Cortical activation during clock reading as a quadratic function of dementia state.
Dementia
Daily rhythm of serum melatonin levels and effect of light exposure in patients with dementia of the Alzheimer's type.
Dementia
Decreased cognitive functioning in patients with advanced oral squamous cell carcinoma.
Dementia
Dementia in Hungary: General practitioners' routines and perspectives regarding early recognition.
Dementia
Diabetes and cognitive outcomes in a nationally representative sample: the National Health and Aging Trends Study.
Dementia
Diagnostic accuracy of the clock drawing test: the relevance of "time setting'' in screening for dementia.
Dementia
Diagnostic Accuracy of the Overlapping Infinity Loops, Wire Cube, and Clock Drawing Tests for Cognitive Impairment in Mild Cognitive Impairment and Dementia.
Dementia
Diagnostic accuracy of the Phototest for cognitive impairment and dementia in Argentina.
Dementia
Diagnostic Performance of Clock Drawing Test by CLOX in an Asian Chinese population.
Dementia
Diagnostic value of digital clock drawing test in comparison with CERAD neuropsychological battery total score for discrimination of patients in the early course of Alzheimer's disease from healthy individuals.
Dementia
Discrimination of dementia with lewy bodies from Alzheimer disease and Parkinson disease using the clock drawing test.
Dementia
Do Lesions Involving the Cortical Cholinergic Pathways Help or Hinder Efficacy of Donepezil in Patients with Alzheimer's Disease?
Dementia
Do vascular lesions and related risk factors influence responsiveness to donepezil chloride in patients with Alzheimer's disease?
Dementia
Does the Clock Drawing Test Predict Dementia? Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+).
Dementia
Effect of education on the clock-drawing dementia screen in non-demented elderly persons.
Dementia
Effects of education, literacy, and dementia on the Clock Drawing Test performance.
Dementia
Effects of Exercise on Cognition: The Finnish Alzheimer Disease Exercise Trial: A Randomized, Controlled Trial.
Dementia
Estimation of diagnostic performance of dementia screening tests: Mini-Mental State Examination, Mini-Cog, Clock Drawing test and Ascertain Dementia 8 questionnaire.
Dementia
Examining Cognitive Status of Elderly Iranians: Farsi Version of the Modified Mini-Mental State Examination.
Dementia
Factors affecting the results of the clock drawing test in elderly patients hospitalized for physical rehabilitation.
Dementia
Frailty, with or without Cognitive Impairment, is a Strong Predictor of Recurrent Falls in a US Population-Representative Sample of Older Adults.
Dementia
Handgrip Strength Predicts Longitudinal Changes in Clock Drawing Test Performance. An Observational Study in a Sample of Older Non-Demented Adults.
Dementia
Hearing impairment is associated with cognitive function in community-dwelling older adults: A cross-sectional study.
Dementia
Hierarchical Development of Frailty and Cognitive Impairment: Clues into Etiological Pathways.
Dementia
Impacting dementia and cognitive loss with innovative strategies: mechanistic target of rapamycin, clock genes, circular non-coding ribonucleic acids, and Rho/Rock.
Dementia
Increased Diagnostic Accuracy of Digital vs. Conventional Clock Drawing Test for Discrimination of Patients in the Early Course of Alzheimer's Disease from Cognitively Healthy Individuals.
Dementia
Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease.
Dementia
Is the Clock Drawing Test a screening tool for the diagnosis of mild cognitive impairment? A systematic review.
Dementia
Is the clock drawing test appropriate for screening for mild cognitive impairment?--Results of the German study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe).
Dementia
Learning Classification Models of Cognitive Conditions from Subtle Behaviors in the Digital Clock Drawing Test.
Dementia
Limitations in differentiating vascular dementia from Alzheimer's disease with brief cognitive tests.
Dementia
Longitudinal association between diabetes and cognitive decline: The National Health and Aging Trends Study.
Dementia
Longitudinal changes in clock drawing test (CDT) performance according to dementia subtypes and severity.
Dementia
MARIO Project: Validation and Evidence of Service Robots for Older People with Dementia.
Dementia
Metabolic alterations associated with impaired clock drawing in Lewy body dementia.
Dementia
Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases.
Dementia
Neuropsychiatric symptoms and executive function impairments in Alzheimer's disease and vascular dementia: The role of subcortical circuits.
Dementia
Neuropsychological Profile and Dementia Symptom Recognition in Help-Seekers in a Community Early-Detection Program in Hong Kong.
Dementia
Noninvasive fractal biomarker of clock neurotransmitter disturbance in humans with dementia.
Dementia
Normal peripheral circadian phase in the old-old with abnormal circadian behavior.
Dementia
Normative performance on the executive clock drawing task in a multi-ethnic bilingual cohort: a project FRONTIER study.
Dementia
Normative References for Graphomotor and Latency Digital Clock Drawing Metrics for Adults Age 55 and Older: Operationalizing the Production of a Normal Appearing Clock.
Dementia
Nothing to complain about? Residents' and relatives' views on a "good life" and ethical challenges in nursing homes.
Dementia
Performance of three clock scoring systems across different ranges of dementia severity.
Dementia
Poorer clock draw test scores are associated with greater functional impairment in peripheral artery disease: the Walking and Leg Circulation Study II.
Dementia
Prevalence of Dementia and Mild Cognitive Impairment in a Rural Area of Sivas, Turkey.
Dementia
Psychometric properties of Clock Drawing Test and MMSE or Short Performance Test (SKT) in dementia screening in a memory clinic population.
Dementia
Qualitative analyses of clock drawings in Alzheimer's disease and vascular dementia.
Dementia
Quantitative and qualitative analyses of clock drawing in frontotemporal dementia and Alzheimer's disease.
Dementia
Quantitative and Qualitative Analyses of the Clock Drawing Test in Fall and Non-Fall Patients with Alzheimer's Disease.
Dementia
Quantitative and qualitative analyses of the clock drawing test in mild cognitive impairment and Alzheimer disease: evaluation of a modified scoring system.
Dementia
Quantitative Assessment of the Retina Using OCT and Associations with Cognitive Function.
Dementia
Relation between the clock drawing test (CDT) and structural changes of brain in dementia.
Dementia
Relationships Between Behavioral Syndromes and Cognitive Domains in Alzheimer Disease: The Impact of Mood and Psychosis.
Dementia
Reliability, validity, and diagnostic accuracy of Parkinson's Disease-Cognitive Rating Scale in Iranian patients with idiopathic Parkinson's disease.
Dementia
Rouleau version of the Clock Drawing Test: age- and education-adjusted normative data from a wide Italian sample.
Dementia
Screening for Dementia in Older Adults: Comparison of Mini-Mental State Examination, Mini-Cog, Clock Drawing Test and AD8.
Dementia
Screening for dementia of the alzheimer type in the community: the utility of the Clock Drawing Test.
Dementia
Screening of dementia in Chinese elderly adults by the clock drawing test and the time and change test.
Dementia
Selegiline in the treatment of Alzheimer's disease: a long-term randomized placebo-controlled trial. Czech and Slovak Senile Dementia of Alzheimer Type Study Group.
Dementia
Sensitivity and specificity of the Clock Drawing Test, incorporating Rouleau scoring system, as a screening instrument for questionable and mild dementia: scale development.
Dementia
Shedding a Light on Phototherapy Studies with People having Dementia: A Critical Review of the Methodology from a Light Perspective.
Dementia
Sleep difficulties, incident dementia and all-cause mortality among older adults across 8 years: Findings from the National Health and Aging Trends Study.
Dementia
Staphylococcus aureus carriage in care homes: identification of risk factors, including the role of dementia.
Dementia
Tai Chi and the Protection of Cognitive Ability: A Systematic Review of Prospective Studies in Healthy Adults.
Dementia
Ten-Point Clock Test: a correlation analysis with other neuropsychological tests in dementia.
Dementia
The abbreviated form of the Brief Cognitive Battery in the diagnosis of dementia in Alzheimer's disease.
Dementia
The accuracy of the Clock Drawing Test compared to that of standard screening tests for Alzheimer's disease: results from a study of Brazilian elderly with heterogeneous educational backgrounds.
Dementia
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
Dementia
The clock drawing test as a screening tool in mild cognitive impairment and very mild dementia: a new brief method of scoring and normative data in the elderly.
Dementia
The Clock Drawing Test for dementia of the Alzheimer's type: A comparison of three scoring methods in a memory disorders clinic.
Dementia
The clock drawing test in primary care: sensitivity in dementia detection and specificity against normal and depressed elderly.
Dementia
The clock drawing test is a poor screening tool for postoperative delirium and cognitive dysfunction after aortic repair.
Dementia
The Clock Drawing Test versus Mini-mental Status Examination as a Screening Tool for Dementia: A Clinical Comparison.
Dementia
The Clock Drawing Test: A Reasonable Instrument to Assess Probable Dementia in Primary Care?
Dementia
The clock drawing test: A systematic review and meta-analysis of diagnostic accuracy.
Dementia
The Clock Drawing Test: Performance differences between the free-drawn and incomplete-copy versions in patients with MCI and dementia.
Dementia
The Clock Reading Test: validation of an instrument for the diagnosis of dementia and disorders of visuo-spatial cognition.
Dementia
The Clock Test: a sensitive measure to differentiate normal elderly from those with Alzheimer disease.
Dementia
The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.
Dementia
The four-point scoring system for the clock drawing test does not differentiate between Alzheimer's disease and vascular dementia.
Dementia
The Gesture Imitation in Alzheimer's Disease Dementia and Amnestic Mild Cognitive Impairment.
Dementia
The Impact of Routine Cognitive Screening by Using the Clock Drawing Task in the Evaluation of Elderly Patients in the Emergency Department.
Dementia
The interlocking finger test in patients with Parkinson's disease and healthy subjects.
Dementia
The Mini-Cog versus the Mini-Mental State Examination and the Clock Drawing Test in daily clinical practice: screening value in a German Memory Clinic.
Dementia
The Mini-Cog, Clock Drawing Test, and the Mini-Mental State Examination in a German Memory Clinic: specificity of separation dementia from depression.
Dementia
The Pentagon Copying Test and the Clock Drawing Test as Prognostic Markers in Dementia with Lewy Bodies.
Dementia
The Rapid Cognitive Screen (RCS): A Point-of-Care Screening for Dementia and Mild Cognitive Impairment.
Dementia
The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: Role of the renin angiotensin system inhibition.
Dementia
The sensitivity and specificity of subjective memory complaints and the subjective memory rating scale, deterioration cognitive observee, mini-mental state examination, six-item screener and clock drawing test in dementia screening.
Dementia
The ten point clock test: a quick screen and grading method for cognitive impairment in medical and surgical patients.
Dementia
The use of the Clock Drawing Test in bipolar disorder with or without dementia of Alzheimer's type.
Dementia
The use of the mini-mental state examination and the clock-drawing test for dementia in a tertiary hospital.
Dementia
The utility of the ten-point clock test as a screen for cognitive impairment in general hospital patients.
Dementia
The validation of a mailed health survey for screening of dementia of the Alzheimer's type.
Dementia
The value of the clock drawing test and the mini-mental state examination for identifying vascular cognitive impairment no dementia.
Dementia
Trajectories and risk factors of dementia progression: a memory clinic cohort followed up to 3 years from diagnosis.
Dementia
Usefulness of the Clock Drawing Test as a Cognitive Screening Instrument for Mild Cognitive Impairment and Mild Dementia: an Evaluation Using Three Scoring Systems.
Dementia
Validation of a Spanish translation of the CLOX for use in Hispanic samples: the Hispanic EPESE study.
Dementia
Validation of the Greek version of the Abbreviated Mental Test Score: Preliminary findings for cognitively impaired patients of different etiology.
Dementia
Validity and Clinical Utility of Different Clock Drawing Test Scoring Systems in Multiple Forms of Dementia.
Dementia
Validity of clock drawing test (CDT), scoring by Chula clock-drawing scoring system (CCSS) in screening dementia among Thai elderly in community.
Dementia
Visual spatial abilities and fall risk: an assessment tool for individuals with dementia.
Dementia
Visuospatial Dysfunction May Be a Key in the Differentiation between Alzheimer's Disease and Subcortical Cognitive Impairment in Moderate to Severe Stages.
Dementia
Which factors are associated with global cognitive impairment in Wilson's disease?
Dementia
Yoga-plus exercise mix promotes cognitive, affective, and physical functions in elderly people.
Dementia
[A proposal for application and scoring of the Clock Drawing Test in Alzheimer's disease]
Dementia
[Clock drawing in dementia: its reliability and relation to the neuropsychological measures]
Dementia
[Efficacy of actovegin in the treatment of elderly patients with vascular mild cognitive impairment].
Dementia
[Light therapy can restore a disturbed sleep/wake rhythm in dementia: but what is the basis of its efficacy?]
Dementia
[Memantine (akatinol) therapy of cognitive impairment in Parkinson's disease complicated by dementia]
Dementia
[Performance of cognitive brief test in elderly patients with dementia in advanced stage living in an urban community of Lima, Peru].
Dementia
[Validation of the clock drawing test - Manos´ version - as a screening test for detection of dementia in older persons of Lima, Peru].
Dementia, Vascular
Can clock drawing differentiate Alzheimer's disease from other dementias?
Dementia, Vascular
Can clock drawing test help to differentiate between dementia of the Alzheimer's type and vascular dementia? A preliminary study.
Dementia, Vascular
Classifying Non-Dementia and Alzheimer's Disease/Vascular Dementia Patients Using Kinematic, Time-Based, and Visuospatial Parameters: The Digital Clock Drawing Test.
Dementia, Vascular
Clock drawing errors in dementia: neuropsychological and neuroanatomical considerations.
Dementia, Vascular
Clock drawing test: correlation with linear measurements of CT studies in demented patients.
Dementia, Vascular
Cognitive Screening Tool for Geriatrics: A Retrospective Observational Study on the Correlation of the Scores in 30-Point Clock Face Test and MMSE.
Dementia, Vascular
Cross-sectional and longitudinal association between antihypertensive medications and cognitive impairment in an elderly population.
Dementia, Vascular
Diagnostic Performance of Clock Drawing Test by CLOX in an Asian Chinese population.
Dementia, Vascular
Evil and elder abuse: intersections of Paul Ricoeur's and Simone Weil's perspectives on evil with one abused older woman's narrative.
Dementia, Vascular
Qualitative analyses of clock drawings in Alzheimer's disease and vascular dementia.
Dementia, Vascular
Ten-Point Clock Test: a correlation analysis with other neuropsychological tests in dementia.
Dementia, Vascular
The four-point scoring system for the clock drawing test does not differentiate between Alzheimer's disease and vascular dementia.
Dementia, Vascular
Use of the ten-point clock test to compare executive functioning across 24 months in patients with subcortical vascular dementia.
Demyelinating Diseases
New Cortical Neurodegenerative Pathways in the Hypertensive Rat Brain.
Dengue
Cloning and daily expression of the timeless gene in Aedes aegypti (Diptera:Culicidae).
Dengue
Dengue virus replicons: Production of an interserotypic chimera and cell lines from different species, and establishment of a cell-based fluorescent assay to screen inhibitors, validated by the evaluation of ribavirin's activity.
Dengue
Evolution, dispersal and replacement of American genotype dengue type 2 viruses in India (1956-2005): selection pressure and molecular clock analyses.
Dengue
Extensive circadian and light regulation of the transcriptome in the malaria mosquito Anopheles gambiae.
Dengue
Molecular characterization and genotype shift of dengue virus strains between 2001 and 2014 in Guangzhou.
Dengue
Phylogenetic and Molecular Clock Analysis of Dengue Serotype 1 and 3 from New Delhi, India.
Dengue
[Phylogenetic analysis of envelope gene of dengue virus serotype 2 in Guangzhou, 2001-2015].
Dermatitis
Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice.
Dermatitis
Effects of Genetic Polymorphisms of N-Acetyltransferase on Trichloroethylene-Induced Hypersensitivity Dermatitis among Exposed Workers.
Dermatitis, Allergic Contact
Human arylamine N-acetyltransferase 2 polymorphism and susceptibility to allergic contact dermatitis.
Dermatitis, Atopic
N-acetyltransferase 2 acetylation polymorphism: prevalence of slow acetylators does not differ between atopic dermatitis patients and healthy subjects.
Dermatitis, Atopic
The Clock Genes Are Involved in The Deterioration of Atopic Dermatitis after Day-and-Night Reversed Physical Stress in NC/Nga Mice.
Dermatitis, Atopic
Ultraviolet A Eye Irradiation Ameliorates Atopic Dermatitis via p53 and Clock Gene Proteins in NC/Nga Mice.
Dermatitis, Contact
Biological clock dysfunction exacerbates contact hypersensitivity in mice.
Dermatitis, Phototoxic
Effects and mechanisms of action of light-emitting diodes on the human retina and internal clock.
Dermoid Cyst
Clinical decision upon resection or observation of ocular surface dermoid lesions with the visual axis unaffected in pediatric patients.
Diabetes Insipidus
Molecular clock is involved in predictive circadian adjustment of renal function.
Diabetes Mellitus
Are Type 2 Diabetes Mellitus and Depression Part of a Common Clock Genes Network?
Diabetes Mellitus
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
Diabetes Mellitus
Circadian clock genes and myocardial infarction in patients with type 2 diabetes mellitus.
Diabetes Mellitus
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.
Diabetes Mellitus
Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.
Diabetes Mellitus
Cognitive impairment with diabetes mellitus and metabolic disease: innovative insights with the mechanistic target of rapamycin and circadian clock gene pathways.
Diabetes Mellitus
Correlation between inflammatory markers and impaired circadian clock gene expression in type 2 diabetes mellitus.
Diabetes Mellitus
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Diabetes Mellitus
Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes?
Diabetes Mellitus
Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity.
Diabetes Mellitus
Evidence for a dysfunction and disease-promoting role of the circadian clock in the diabetic retina.
Diabetes Mellitus
Expression of clock gene Dbp in omental and mesenteric adipose tissue in patients with type 2 diabetes.
Diabetes Mellitus
Gut microbiota: closely tied to the regulation of circadian clock in the development of type 2 diabetes mellitus.
Diabetes Mellitus
Hormones and the autonomic nervous system are involved in suprachiasmatic nucleus modulation of glucose homeostasis.
Diabetes Mellitus
N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population.
Diabetes Mellitus
N-acetyltransferase-2 genotypes among Jordanian patients with diabetes mellitus.
Diabetes Mellitus
Poor Sleep Quality Is Associated with Dawn Phenomenon and Impaired Circadian Clock Gene Expression in Subjects with Type 2 Diabetes Mellitus.
Diabetes Mellitus
Roles of HDAC3-orchestrated circadian clock gene oscillations in diabetic rats following myocardial ischaemia/reperfusion injury.
Diabetes Mellitus
Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats.
Diabetes Mellitus
The Framingham Study, diabetes mellitus and cardiovascular disease: turning back the clock.
Diabetes Mellitus
[PHENOTYPIC POLYMORPHISM OF N-ACETYLTRANSFERASE 2 IN PATIENTS WITH DIABETES MELLITUS].
Diabetes Mellitus
[Role of circadian rhythms and cellular clock in aging-related diseases].
Diabetes Mellitus, Type 1
Clock Gene Expression in the Liver of Streptozotocin-induced and Spontaneous Type 1 Diabetic Rats.
Diabetes Mellitus, Type 1
The clock is ticking: Parental stress around emerging adulthood for adolescents with type 1 diabetes.
Diabetes Mellitus, Type 2
"Diabetes of the elderly" and type 2 diabetes in younger patients: possible role of the biological clock.
Diabetes Mellitus, Type 2
A Review of Data of Findings on Night Shift Work and the Development of DM and CVD Events: a Synthesis of the Proposed Molecular Mechanisms.
Diabetes Mellitus, Type 2
A Topological Cluster of Differentially Regulated Genes in Mice Lacking PER3.
Diabetes Mellitus, Type 2
A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.
Diabetes Mellitus, Type 2
Are Type 2 Diabetes Mellitus and Depression Part of a Common Clock Genes Network?
Diabetes Mellitus, Type 2
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
Diabetes Mellitus, Type 2
At the Intersection of Microbiota and Circadian Clock: Are Sexual Dimorphism and Growth Hormones the Missing Link to Pathology?: Circadian Clock and Microbiota: Potential Egffect on Growth Hormone and Sexual Development.
Diabetes Mellitus, Type 2
Autonomous and self-sustained circadian oscillators displayed in human islet cells.
Diabetes Mellitus, Type 2
Cellular circadian period length inversely correlates with HbA1c levels in individuals with type 2 diabetes.
Diabetes Mellitus, Type 2
Chronomedicine and type 2 diabetes: shining some light on melatonin.
Diabetes Mellitus, Type 2
Circadian clock gene expression is impaired in gestational diabetes mellitus.
Diabetes Mellitus, Type 2
Circadian clock genes and myocardial infarction in patients with type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats.
Diabetes Mellitus, Type 2
Comment on Jakubowicz et al. Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 Diabetes Consuming a Three-Meal Diet: A Randomized Clinical Trial. Diabetes Care 2019;42:2171-2180.
Diabetes Mellitus, Type 2
Common genetic variation in circadian clock genes are associated with cardiovascular risk factors in an African American and Hispanic/Latino cohort.
Diabetes Mellitus, Type 2
Complex disease interventions from a network model for type 2 diabetes.
Diabetes Mellitus, Type 2
Computational modeling and analysis of the impacts of sleep deprivation on glucose stimulated insulin secretion.
Diabetes Mellitus, Type 2
Correlation between inflammatory markers and impaired circadian clock gene expression in type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
CRY1 circadian gene variant interacts with carbohydrate intake for insulin resistance in two independent populations: Mediterranean and North American.
Diabetes Mellitus, Type 2
Diet-induced insulin resistance state disturbs brain clock processes and alters tuning of clock outputs in the Sand rat, Psammomys obesus.
Diabetes Mellitus, Type 2
Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals.
Diabetes Mellitus, Type 2
Does exercise training impact clock genes in patients with coronary artery disease and type 2 diabetes mellitus?
Diabetes Mellitus, Type 2
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
Diabetes Mellitus, Type 2
Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes?
Diabetes Mellitus, Type 2
Enhanced effect of daytime restricted feeding on the circadian rhythm of streptozotocin-induced type 2 diabetic rats.
Diabetes Mellitus, Type 2
Experimental and clinical aspects of melatonin and clock genes in diabetes.
Diabetes Mellitus, Type 2
Expression of clock gene Dbp in omental and mesenteric adipose tissue in patients with type 2 diabetes.
Diabetes Mellitus, Type 2
Gut microbiota: closely tied to the regulation of circadian clock in the development of type 2 diabetes mellitus.
Diabetes Mellitus, Type 2
Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial.
Diabetes Mellitus, Type 2
Interplay between diet, exercise and the molecular circadian clock in orchestrating metabolic adaptations of adipose tissue.
Diabetes Mellitus, Type 2
Loss of arginine vasopressin- and vasoactive intestinal polypeptide-containing neurons and glial cells in the suprachiasmatic nucleus of individuals with type 2 diabetes.
Diabetes Mellitus, Type 2
Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.
Diabetes Mellitus, Type 2
N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population.
Diabetes Mellitus, Type 2
Poor Sleep Quality Is Associated with Dawn Phenomenon and Impaired Circadian Clock Gene Expression in Subjects with Type 2 Diabetes Mellitus.
Diabetes Mellitus, Type 2
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Diabetes Mellitus, Type 2
Pro-inflammatory Cytokine Interleukin 1? Disrupts ? cell Circadian Clock Function and Regulation of Insulin Secretion.
Diabetes Mellitus, Type 2
Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 Diabetes Consuming a Three-Meal Diet: A Randomized Clinical Trial.
Diabetes Mellitus, Type 2
Response to Comment on Jakubowicz et al. Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 Diabetes Consuming a Three-Meal Diet: A Randomized Clinical Trial. Diabetes Care 2019;42:2171-2180.
Diabetes Mellitus, Type 2
Role of High Energy Breakfast "Big Breakfast Diet" in Clock Gene Regulation of Postprandial Hyperglycemia and Weight Loss in Type 2 Diabetes.
Diabetes Mellitus, Type 2
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Diabetes Mellitus, Type 2
Should we listen to our clock to prevent type 2 diabetes mellitus?
Diabetes Mellitus, Type 2
Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes.
Diabetes Mellitus, Type 2
Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats.
Diabetes Mellitus, Type 2
The major circadian pacemaker ARNT-like protein-1 (BMAL1) is associated with susceptibility to gestational diabetes mellitus.
Diabetes Mellitus, Type 2
Time-Restricted Feeding Improves Glucose Tolerance in Men at Risk for Type 2 Diabetes: A Randomized Crossover Trial.
Diabetes Mellitus, Type 2
Timing of food intake during simulated night shift impacts glucose metabolism: A controlled study.
Diabetes Mellitus, Type 2
[PHENOTYPIC POLYMORPHISM OF N-ACETYLTRANSFERASE 2 IN PATIENTS WITH DIABETES MELLITUS].
Diabetes Mellitus, Type 2
[Role of circadian rhythms and cellular clock in aging-related diseases].
Diabetes, Gestational
Circadian clock gene expression is impaired in gestational diabetes mellitus.
Diabetes, Gestational
Nuclear receptors, gestational metabolism and maternal metabolic disorders.
Diabetes, Gestational
Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels.
Diabetic Nephropathies
Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB.
Diabetic Nephropathies
The N-acetyltransferase (NAT) gene: an early risk marker for diabetic nephropathy in Japanese type 2 diabetic patients?
Diabetic Retinopathy
Changes in the daily rhythm of lipid metabolism in the diabetic retina.
Diabetic Retinopathy
Clock genes and behavioral responses to light are altered in a mouse model of diabetic retinopathy.
Diabetic Retinopathy
Diabetic retinopathy alters light-induced clock gene expression and dopamine levels in the mouse retina.
Diabetic Retinopathy
Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.
Diabetic Retinopathy
Evidence for a dysfunction and disease-promoting role of the circadian clock in the diabetic retina.
Diabetic Retinopathy
Tumor Necrosis Factor Alpha (TNF-?) Disrupts Kir4.1 Channel Expression Resulting in Müller Cell Dysfunction in the Retina.
DiGeorge Syndrome
MOZ Regulates the Tbx1 Locus, and Moz Mutation Partially Phenocopies DiGeorge Syndrome.
Diphtheria
Negative selection with the Diphtheria toxin A fragment gene improves frequency of Cre-mediated cassette exchange in ES cells.
Diplopia
[The relation of the motion velocity of the real image to the velocity of illusory image in diplopia studied by the clock method]
Disorders of Excessive Somnolence
3111T/C clock gene polymorphism is not associated with sleep disturbances in untreated depressed patients.
Disorders of Excessive Somnolence
Circadian clock genes and circadian phenotypes in patients with myocardial infarction.
Disorders of Excessive Somnolence
Circadian rhythms in narcolepsy: studies on a 90 minute day.
Disorders of Excessive Somnolence
Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind.
Disorders of Excessive Somnolence
Genetic dissection of drug effects in clinical practice: CLOCK gene and clozapine-induced diurnal sleepiness.
Disorders of Excessive Somnolence
How does diurnal intermittent fasting impact sleep, daytime sleepiness, and markers of the biological clock? Current insights.
Disorders of Excessive Somnolence
Selective effects of CPAP on sleep apnoea-associated manifestations.
Disorders of Excessive Somnolence
[Sleep quality and daytime sleepiness in schizophrenia spectrum disorders during antipsychotic treatment]
Diverticular Diseases
No need to watch the clock: persistence during laparoscopic sigmoidectomy for diverticular disease.
Down Syndrome
Cyclin B in mouse oocytes and embryos: importance for human reproduction and aneuploidy.
Drug Hypersensitivity
Evaluation of polymorphisms in the sulfonamide detoxification genes NAT2, CYB5A, and CYB5R3 in patients with sulfonamide hypersensitivity.
Drug-Related Side Effects and Adverse Reactions
Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil.
Drug-Related Side Effects and Adverse Reactions
Discordance between N-acetyltransferase 2 phenotype and genotype in a population of Hmong subjects.
Drug-Related Side Effects and Adverse Reactions
Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues.
Drug-Related Side Effects and Adverse Reactions
Improving the reporting of adverse drug reactions in the hospital setting.
Drug-Related Side Effects and Adverse Reactions
Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid.
Drug-Related Side Effects and Adverse Reactions
N-acetyltransferase polymorphism among northern Sudanese.
Drug-Related Side Effects and Adverse Reactions
ORAL ADVERSE DRUG REACTIONS TO CARDIOVASCULAR DRUGS.
Drug-Related Side Effects and Adverse Reactions
TaqMan real time-polymerase chain reaction methods for determination of nucleotide polymorphisms in human N-acetyltransferase-1 (NAT1) and -2 (NAT2).
Drug-Related Side Effects and Adverse Reactions
[Sleep quality and daytime sleepiness in schizophrenia spectrum disorders during antipsychotic treatment]
Ductus Arteriosus, Patent
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Duodenal Ulcer
Seasonality in duodenal ulcer disease: possible relationship with circannually cycling neurons enclosed in the biological clock.
Dyscalculia
[Acalculia with clock agnosia in a patient with right cerebral hemisphere lesion and hidden lefthandedness]
Dyskinesias
Effects of histone acetyltransferase inhibitors on L-DOPA-induced dyskinesia in a murine model of Parkinson's disease.
Dyslipidemias
Acetylator Genotype-Dependent Dyslipidemia in Rats Congenic for N-Acetyltransferase 2.
Dyslipidemias
Common genetic variation in circadian clock genes are associated with cardiovascular risk factors in an African American and Hispanic/Latino cohort.
Dyslipidemias
Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation.
Dyslipidemias
Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression.
Dyslipidemias
Short-term circadian disruption impairs bile acid and lipid homeostasis in mice.
Dysostoses
Altered Cogs of the Clock: Insights into the Embryonic Etiology of Spondylocostal Dysostosis.
Dysplastic Nevus Syndrome
Role of Tip60 in Human Melanoma Cell Migration, Metastasis, and Patient Survival.
Dyspnea
Circadian changes in effectiveness of corticosteroids in eight patients with allergic asthma.
Dyssomnias
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Ectropion
Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes: The ABCDEF Guide.
Elephantiasis, Filarial
Exploring factors affecting quality implementation of lymphatic filariasis mass drug administration in Bole and Central Gonja Districts in Northern Ghana.
Encephalitis
Refractory Catatonia Due to N-methyl-D-Aspartate Receptor Encephalitis Responsive to Electroconvulsive Therapy: The Clinical Use of the Clock Drawing Test.
Encephalomyelitis
IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis.
Endometrial Neoplasms
Histone acetyltransferase MOF is involved in suppression of endometrial cancer and maintenance of ER? stability.
Endometriosis
Lack of association between endometriosis and N-acetyl transferase 1 (NAT1) and 2 (NAT2) polymorphisms in a Japanese population.
Endometriosis
NAT2 gene polymorphisms and endometriosis risk: A PRISMA-compliant meta-analysis.
Endotoxemia
Clock-controlled StAR's expression and corticosterone production contribute to the endotoxemia immune response.
Endotoxemia
Constant light exposure aggravates POMC-mediated muscle wasting associated with hypothalamic alteration of circadian clock and SIRT1 in endotoxemia rats.
Enteritis
Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis.
Epilepsies, Partial
Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy.
Epilepsy
16p13 microduplication without CREBBP involvement: Moving toward a phenotype delineation.
Epilepsy
A single generalized seizure alters the amplitude, but not phase, of the circadian activity rhythm of the hamster.
Epilepsy
Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor.
Epilepsy
Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy.
Epilepsy
CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development.
Epilepsy
Chronobiology of epilepsy: diagnostic and therapeutic implications of chrono-epileptology.
Epilepsy
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Epilepsy
Disruption of light-induced c-Fos immunoreactivity in the suprachiasmatic nuclei of chronic epileptic rats.
Epilepsy
Diurnal Variation Has Effect on Differential Gene Expression Analysis in the Hippocampus of the Pilocarpine-Induced Model of Mesial Temporal Lobe Epilepsy.
Epilepsy
Dysregulation of REV-ERB? impairs GABAergic function and promotes epileptic seizures in preclinical models.
Epilepsy
Epilepsy Occurrence and Circadian Rhythm: A Bibliometrics Study and Visualization Analysis via CiteSpace.
Epilepsy
Genetic diagnoses in epilepsy: The impact of dynamic exome analysis in a pediatric cohort.
Epilepsy
Molecular mechanism of circadian rhythmicity of seizures in temporal lobe epilepsy.
Epilepsy
Moving the clock on comprehensive post-surgical outcome assessment in specific etiological categories of epilepsy.
Epilepsy
Paroxysmal Movement Disorder and Epilepsy Caused by a De Novo Truncating Mutation in KAT6A.
Epilepsy
PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.
Epilepsy
Recording human electrocorticographic (ECoG) signals for neuroscientific research and real-time functional cortical mapping.
Epilepsy
Rhythms of Core Clock Genes and Spontaneous Locomotor Activity in Post-Status Epilepticus Model of Mesial Temporal Lobe Epilepsy.
Epilepsy
The circadian rhythm and its interaction with human epilepsy: A review of literature.
Epilepsy
The Molecular Genetic Interaction Between Circadian Rhythms and Susceptibility to Seizures and Epilepsy.
Epilepsy
Uncovering the Pharmacological Mechanism of Chaibei Zhixian Decoction on Epilepsy by Network Pharmacology Analysis.
Epilepsy, Frontal Lobe
Bidirectional relationships of sleep and epilepsy in adults with epilepsy.
Epilepsy, Temporal Lobe
Aberrant expression of PAR bZIP transcription factors is associated with epileptogenesis, focus on hepatic leukemia factor.
Epilepsy, Temporal Lobe
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Epilepsy, Temporal Lobe
Rhythms of Core Clock Genes and Spontaneous Locomotor Activity in Post-Status Epilepticus Model of Mesial Temporal Lobe Epilepsy.
Epstein-Barr Virus Infections
Intranuclear localization of the transcription coadaptor CBP/p300 and the transcription factor RBP-Jk in relation to EBNA-2 and -5 in B lymphocytes.
Erectile Dysfunction
The image of the heart and the synergic principle in psychoanalysis (psychosynergy). II. Three dreams of the disguised heart-image. III. The disguised image of the heart in a case of severe sexual impotence and talent inhibition; the case of the clock chimer (paroxysmal auricular tachycardia in father and son).
Esophageal Neoplasms
Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery.
Esophageal Neoplasms
Association of genetic polymorphisms of N-acetyltransferase 2 and susceptibility to esophageal cancer in north Indian population.
Esophageal Neoplasms
Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes.
Esophageal Neoplasms
Circadian variability of pharmacokinetics of 5-fluorouracil and CLOCK T3111C genetic polymorphism in patients with esophageal carcinoma.
Esophageal Neoplasms
Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer.
Esophageal Neoplasms
N-acetyltransferase 2 phenotype and risk of esophageal cancer: A meta analysis.
Esophageal Neoplasms
N-acetyltransferase 2 polymorphisms and risk of esophageal cancer in a Chinese population.
Esophageal Squamous Cell Carcinoma
A novel long noncoding RNA linc00460 upregulated by CBP/P300 promotes carcinogenesis in Esophageal Squamous Cell Carcinoma.
Esophageal Squamous Cell Carcinoma
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex.
Esophageal Squamous Cell Carcinoma
LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.
Esophagitis, Peptic
Changes in Clock Genes Expression in Esophagus in Rat Reflux Esophagitis.
Essential Hypertension
Association of insulin resistance with polymorphic variants of Clock and Bmal1 genes: A case-control study.
Essential Hypertension
Daily nighttime melatonin reduces blood pressure in male patients with essential hypertension.
Essential Tremor
When do essential tremor patients develop head tremor? Influences of age and duration and evidence of a biological clock.
Exanthema
"The clock is ticking": the timely management of a painful skin rash in a seventy-year-old woman.
Exostoses
A novel truncating variant within exon 7 of KAT6B associated with features of both Say-Barber-Bieseker-Young-Simpson syndrome and genitopatellar syndrome: Further evidence of a continuum in the clinical spectrum of KAT6B-related disorders.
Extensively Drug-Resistant Tuberculosis
Unexpected N-acetylation of capreomycin by mycobacterial Eis enzymes.
Eye Diseases
Circadian organization of the mammalian retina: from gene regulation to physiology and diseases.
Eye Diseases
Dopamine 2 Receptor Activation Entrains Circadian Clocks in Mouse Retinal Pigment Epithelium.
Eye Diseases
Evolution of visual sensory system in cichlid fishes from crater lake Barombi Mbo in Cameroon.
Fanconi Anemia
Tip60 Is Required for DNA Interstrand Cross-link Repair in the Fanconi Anemia Pathway.
Fatigue Syndrome, Chronic
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Fatty Liver
Circadian rhythms of liver physiology and disease: experimental and clinical evidence.
Fatty Liver
Different expressions of clock genes in fatty liver induced by high-sucrose and high-fat diets.
Fatty Liver
Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis.
Fatty Liver
Dysregulation of intercellular signaling by MOF deletion leads to liver injury.
Fatty Liver
Involvement of adenosine monophosphate-activated protein kinase in the influence of timed high-fat evening diet on the hepatic clock and lipogenic gene expression in mice.
Fatty Liver
MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice.
Fatty Liver
Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies.
Fatty Liver
Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease.
Fatty Liver
Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.
Fatty Liver
Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes.
Fatty Liver
Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model.
Fatty Liver
The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis.
Fatty Liver
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Fatty Liver
Tick-Tock Hedgehog-Mutual crosstalk with liver circadian clock promotes liver steatosis.
Fatty Liver
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.
Fatty Liver, Alcoholic
Effect of chronic ethanol exposure on the liver of Clock-mutant mice.
Femoracetabular Impingement
Clinical Outcomes of Hip Arthroscopy for Hip Labrum Calcification in Young and Middle-Aged Patients.
Fetal Alcohol Spectrum Disorders
Epigenetic Clock Analysis in Children With Fetal Alcohol Spectrum Disorder.
Fetal Alcohol Spectrum Disorders
[Effects of ethanol on the development of circadian time keeping system]
Fibromyalgia
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Fibromyalgia
Validity and reliability of the clock drawing test as a screening tool for cognitive impairment in patients with fibromyalgia.
Fibrosarcoma
Daily rhythms are retained both in spontaneously developed sarcomas and in xenografts grown in immunocompromised SCID mice.
Fibrosarcoma
The kruppel-like protein gli-similar 3 (glis3) functions as a key regulator of insulin transcription.
Food Hypersensitivity
Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model.
Food Hypersensitivity
Genotype of N-acetyltransferase 2 (NAT2) polymorphism in children with immunoglobulin E-mediated food allergy.
Fragile X Syndrome
Circadian biology and sleep in monogenic neurological disorders and its potential application in drug discovery.
Fragile X Syndrome
Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.
Frontotemporal Dementia
Executive Abilities as Reflected by Clock Hand Placement: Frontotemporal Dementia Versus Early-Onset Alzheimer Disease.
Frontotemporal Dementia
Quantitative and qualitative analyses of clock drawing in frontotemporal dementia and Alzheimer's disease.
Gallbladder Neoplasms
KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer.
Gallbladder Neoplasms
Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
Ganglion Cysts
Melatonin and 5-methoxytryptophol (5-ML) in nervous and/or neurosensory structures of a gastropod mollusc (Helix aspersa maxima): synthesis and diurnal rhythms.
Gastroesophageal Reflux
Changes in Clock Genes Expression in Esophagus in Rat Reflux Esophagitis.
Gastrointestinal Diseases
Disruption of Circadian Rhythms and Gut Motility: An Overview of Underlying Mechanisms and Associated Pathologies.
Gastrointestinal Neoplasms
Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer.
Gastrointestinal Neoplasms
[Preoperative cognitive function in very old patients : Influence on the complication rate and length of hospitalization].
Gastrointestinal Stromal Tumors
An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells.
Genetic Diseases, Inborn
A Comprehensive, High-Resolution Map of a Gene's Fitness Landscape.
Genetic Diseases, Inborn
A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy.
Genetic Diseases, Inborn
A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase Naa10S37P mutant.
Genetic Diseases, Inborn
An individual with blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) and additional features expands the phenotype associated with mutations in KAT6B.
Genetic Diseases, Inborn
Biochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defects.
Genetic Diseases, Inborn
CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.
Genetic Diseases, Inborn
De Novo KAT5 Variants Cause a Syndrome with Recognizable Facial Dysmorphisms, Cerebellar Atrophy, Sleep Disturbance, and Epilepsy.
Genetic Diseases, Inborn
Floating-Harbor syndrome and polycystic kidneys associated with SRCAP mutation.
Genetic Diseases, Inborn
NAA10 p.(D10G) and NAA10 p.(L11R) Variants Hamper Formation of the NatA N-Terminal Acetyltransferase Complex.
Genetic Diseases, Inborn
NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy.
Genetic Diseases, Inborn
Severe syndromic ID and skewed X-inactivation in a girl with NAA10 dysfunction and a novel heterozygous de novo NAA10 p.(His16Pro) variant - a case report.
Genetic Diseases, Inborn
The Biological Clock and the Molecular Basis of Lysosomal Storage Diseases.
Genital Diseases, Female
Adolescent Dietary Habit-induced Obstetric and Gynecologic Disease (ADHOGD) as a New Hypothesis-Possible Involvement of Clock System.
Giardiasis
Interleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia.
Gilbert Disease
The role of Gilbert's syndrome and frequent NAT2 slow acetylation polymorphisms in the pharmacokinetics of retigabine.
Glaucoma
Chronotyping glaucoma patients with the Munich ChronoType Questionnaire: A case-control study.
Glaucoma
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids and the Sympathetic Nervous System.
Glaucoma
Comparative study of retinal nerve fiber layer measurement by StratusOCT and GDx VCC, I: correlation analysis in glaucoma.
Glaucoma
Comparison of macular and peripapillary measurements for the detection of glaucoma: an optical coherence tomography study.
Glaucoma
Comparison of Scanning Laser Polarimetry and Optical Coherence Tomography in Preperimetric Glaucoma.
Glaucoma
Development of a Nanofabricated Sensor for Monitoring Intraocular Pressure via Ocular Tissue Strain.
Glaucoma
Glaucomatous retinal nerve fibre layer defects may be identified in Stratus OCT images classified as normal.
Glaucoma
N-acetyltransferase activity and melatonin level in the eyes of glaucomatous chickens.
Glaucoma
Peripapillary choroidal thickness in glaucoma measured with optical coherence tomography.
Glaucoma
Reproducibility of peripapillary retinal nerve fibre layer thickness measurements with spectral domain optical coherence tomography in normal and glaucomatous eyes.
Glaucoma
Utility of CLOCK CHART binocular edition for self-checking the binocular visual field in patients with glaucoma.
Glaucoma, Angle-Closure
Laser Peripheral Iridotomy versus Trabeculectomy as an Initial Treatment for Primary Angle-Closure Glaucoma.
Glaucoma, Angle-Closure
Visual results and complications following posterior iris-fixated posterior chamber lenses at penetrating keratoplasty.
Glaucoma, Open-Angle
Comparison between pilocarpine and timolol on diurnal pressures in open-angle glaucoma.
Glioblastoma
Adjusting the Molecular Clock: The Importance of Circadian Rhythms in the Development of Glioblastomas and Its Intervention as a Therapeutic Strategy.
Glioblastoma
Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124.
Glioblastoma
Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.
Glioblastoma
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Glioblastoma
Models of Epigenetic Age Capture Patterns of DNA Methylation in Glioma Associated with Molecular Subtype, Survival, and Recurrence.
Glioblastoma
Proliferative Glioblastoma Cancer Cells Exhibit Persisting Temporal Control of Metabolism and Display Differential Temporal Drug Susceptibility in Chemotherapy.
Glioblastoma
The TICking clock of EGFR therapy resistance in glioblastoma: Target Independence or target Compensation.
Glioblastoma
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Glioma
A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.
Glioma
Association of Circadian Clock Gene Expression with Glioma Tumor Microenvironment and Patient Survival.
Glioma
Cancer stem cell generation during epithelial-mesenchymal transition is temporally gated by intrinsic circadian clocks.
Glioma
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Glioma
Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124.
Glioma
Clock-Controlled Mitochondrial Dynamics Correlates with Cyclic Pregnenolone Synthesis.
Glioma
Correction to: inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness.
Glioma
Correlation between deregulated expression of PER2 gene and degree of glioma malignancy.
Glioma
Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells.
Glioma
EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.
Glioma
Genetic polymorphisms in glutathione S-transferase mu and theta, N-acetyltransferase, and CYP1A1 and risk of gliomas.
Glioma
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Glioma
Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway.
Glioma
Hypoxia, metabolism, and the circadian clock: new links to overcome radiation resistance in high-grade gliomas.
Glioma
Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.
Glioma
IDH1 gene mutation activates Smad signaling molecules to regulate the expression levels of cell cycle and biological rhythm genes in human glioma U87?MG cells.
Glioma
Impact of chronically alternating light-dark cycles on circadian clock mediated expression of cancer (glioma)-related genes in the brain.
Glioma
Inhibition of p38 MAPK activity leads to cell type-specific effects on the molecular circadian clock and time-dependent reduction of glioma cell invasiveness.
Glioma
LncRNA UCA1 facilitated cell growth and invasion through the miR-206/CLOCK axis in glioma.
Glioma
Microglial Exosome miR-7239-3p Promotes Glioma Progression by Regulating Circadian Genes.
Glioma
Models of Epigenetic Age Capture Patterns of DNA Methylation in Glioma Associated with Molecular Subtype, Survival, and Recurrence.
Glioma
MYST1/KAT8 contributes to tumor progression by activating EGFR signaling in glioblastoma cells.
Glioma
Noradrenaline induces clock gene Per1 mRNA expression in C6 glioma cells through beta(2)-adrenergic receptor coupled with protein kinase A - cAMP response element binding protein (PKA-CREB) and Src-tyrosine kinase - glycogen synthase kinase-3beta (Src-GSK-3beta).
Glioma
Period2 downregulation inhibits glioma cell apoptosis by activating the MDM2-TP53 pathway.
Glioma
Temperature-amplitude coupling for stable biological rhythms at different temperatures.
Glioma
The analysis of deregulated expression and methylation of the PER2 genes in gliomas.
Glioma
The Circadian Gene Clock Plays an Important Role in Cell Apoptosis and the DNA Damage Response In Vitro.
Glioma
Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma.
Glioma
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Glioma
[The Mechanism Study on Histone Acetylation Activating Glioblastoma-derived Neurotrophic Factor Transcription].
Glomerulonephritis, Membranous
Membranous nephropathy, hydrocarbon exposure and genetic variants of hydrocarbon detoxification.
Glucose Intolerance
An intrinsic circadian clock of the pancreas is required for normal insulin release and glucose homeostasis in mice.
Glucose Intolerance
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Glucose Intolerance
Female Clock?19/?19 Mice are Protected from the Development of Age-Dependent Cardiomyopathy.
Glucose Intolerance
Induction of Core Circadian Clock Transcription Factor Bmal1 Enhances ?-Cell Function and Protects Against Obesity-Induced Glucose Intolerance.
Glucose Intolerance
Influence of Age on Clock Gene Expression in Peripheral Blood Cells of Healthy Women.
Glucose Intolerance
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Glucose Intolerance
miRNA-10a-5p Alleviates Insulin Resistance and Maintains Diurnal Patterns of Triglycerides and Gut Microbiota in High-Fat Diet-Fed Mice.
Glucose Intolerance
Pancreatic ? cell enhancers regulate rhythmic transcription of genes controlling insulin secretion.
Glucose Intolerance
Shift work cycle-induced alterations of circadian rhythms potentiate the effects of high fat diet on inflammation and metabolism.
Glucose Intolerance
The Singapore impaired glucose tolerance follow-up study: does the ticking clock go backward as well as forward?
Glucose Metabolism Disorders
Capsaicin Ameliorates the Redox Imbalance and Glucose Metabolism Disorder in an Insulin-Resistance Model via Circadian Clock-Related Mechanisms.
Goldenhar Syndrome
Methods and Challenges in a Cohort Study of Infants and Toddlers With Craniofacial Microsomia: The Clock Study.
Granulomatosis with Polyangiitis
Dysregulation of histone deacetylase and histone acetyltransferase in development of Wegener's granulomatosis.
Graves Disease
Clock gene PERIOD3 polymorphism is associated with susceptibility to Graves' disease but not to Hashimoto's thyroiditis.
Hallucinations
Prevalence of psychiatric symptoms and mental disorders detected in primary care in an elderly Spanish population. The PSICOTARD Study: preliminary findings.
Hashimoto Disease
Analysis of expression of different histone deacetylases in autoimmune thyroid disease.
Head and Neck Neoplasms
Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery.
Head and Neck Neoplasms
N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.
Head and Neck Neoplasms
PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells.
Head and Neck Neoplasms
Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.
Head and Neck Neoplasms
Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer.
Head and Neck Neoplasms
Systems Biology Approaches and Precision Oral Health: A Circadian Clock Perspective.
Head and Neck Neoplasms
[Chronobiological considerations for the management of human head and neck cancer]
Headache Disorders
Cluster headache: evidence for a disorder of circadian rhythm and hypothalamic function.
Headache Disorders
Lack of association between the 3092 T-->C Clock gene polymorphism and cluster headache.
Hearing Loss
Contribution of the N-acetyltransferase 2 polymorphism NAT2*6A to age-related hearing impairment.
Hearing Loss
Hearing impairment is associated with cognitive function in community-dwelling older adults: A cross-sectional study.
Hearing Loss
No association between apolipoprotein E or N-acetyltransferase 2 gene polymorphisms and age-related hearing loss.
Hearing Loss
Sleep Disturbance and Altered Expression of Circadian Clock Genes in Patients With Sudden Sensorineural Hearing Loss.
Hearing Loss, Noise-Induced
A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population.
Hearing Loss, Noise-Induced
Constant Light Dysregulates Cochlear Circadian Clock and Exacerbates Noise-Induced Hearing Loss.
Hearing Loss, Sensorineural
Novel Causative Variants in DYRK1A, KARS, and KAT6A Associated with Intellectual Disability and Additional Phenotypic Features.
Hearing Loss, Sensorineural
Sleep Disturbance and Altered Expression of Circadian Clock Genes in Patients With Sudden Sensorineural Hearing Loss.
Heart Arrest
Clinical review: Continuous and simplified electroencephalography to monitor brain recovery after cardiac arrest.
Heart Arrest
Defibrillator and dispatch center clock synchronization is essential for time-sensitive treatment of cardiac arrest.
Heart Arrest
Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity.
Heart Defects, Congenital
16p13 microduplication without CREBBP involvement: Moving toward a phenotype delineation.
Heart Defects, Congenital
Identification of epigenetic factor KAT2B gene variants for possible roles in congenital heart diseases.
Heart Defects, Congenital
Partial microduplication in the histone acetyltransferase complex member KANSL1 is associated with congenital heart defects in 22q11.2 microdeletion syndrome patients.
Heart Defects, Congenital
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Heart Diseases
A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine.
Heart Diseases
A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
Heart Diseases
Cardiovascular risk factors in confirmed prediabetic individuals. Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?
Heart Diseases
Circadian heart rate and blood pressure variability considered for research and patient care.
Heart Diseases
Female Clock?19/?19 Mice are Protected from the Development of Age-Dependent Cardiomyopathy.
Heart Diseases
Influence of ApoE Genotype and Clock T3111C Interaction with Cardiovascular Risk Factors on the Progression to Alzheimer's Disease in Subjective Cognitive Decline and Mild Cognitive Impairment Patients.
Heart Diseases
The Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid (SAHA) Restores Cardiomyocyte Contractility in a Rat Model of Early Diabetes.
Heart Failure
A Natural p300-Specific Histone Acetyltransferase Inhibitor, Curcumin, in Addition to Angiotensin-Converting Enzyme Inhibitor, Exerts Beneficial Effects on Left Ventricular Systolic Function After Myocardial Infarction in Rats.
Heart Failure
A novel drug delivery system of oral curcumin markedly improves efficacy of treatment for heart failure after myocardial infarction in rats.
Heart Failure
A Structured Measurement of Highly Synchronous Real-Time Ballistocardiography Signal Data of Heart Failure Patients.
Heart Failure
Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan.
Heart Failure
Age-associated disruption of molecular clock expression in skeletal muscle of the spontaneously hypertensive rat.
Heart Failure
Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis.
Heart Failure
Application of curcumin to heart failure therapy by targeting transcriptional pathway in cardiomyocytes.
Heart Failure
Correlation of gene expression and clinical parameters identifies a set of genes reflecting LV systolic dysfunction and morphological alterations.
Heart Failure
Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats.
Heart Failure
Is the Clock Drawing Test useful in the screening assessment of aged patients with chronic heart failure?
Heart Failure
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
Heart Failure
Older people with heart failure and general practitioners - temporal reference frameworks and implications for practice.
Heart Failure
Optimal dose-setting study of curcumin for improvement of left ventricular systolic function after myocardial infarction in rats.
Heart Failure
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Heart Failure
The Clock Mechanism Influences Neurobiology and Adaptations to Heart Failure in Clock?19/?19 Mice With Implications for Circadian Medicine.
Heart Failure
The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats.
Heart Septal Defects, Atrial
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Heart Septal Defects, Ventricular
Down-regulation of EBAF in the heart with ventricular septal defects and its regulation by histone acetyltransferase p300 and transcription factors smad2 and cited2.
Heart Septal Defects, Ventricular
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Hematologic Neoplasms
Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.
Hematologic Neoplasms
Clock genes and cancer development in particular in endocrine tissues.
Hematologic Neoplasms
Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments.
Hematologic Neoplasms
Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.
Hematologic Neoplasms
Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
Hematologic Neoplasms
FGFR1 and KAT6A rearrangements in patients with hematological malignancies and chromosome 8p11 abnormalities: biological and clinical features.
Hematologic Neoplasms
Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.
Hematologic Neoplasms
Make the right measurement: Discovery of an allosteric inhibition site for p300-HAT.
Hematologic Neoplasms
Mice heterozygous for CREB binding protein are hypersensitive to ?-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.
Hematologic Neoplasms
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Hematologic Neoplasms
The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis.
Hematologic Neoplasms
[Advances of Researches on the Role of Histone Modification in Hematological Neoplasms].
Hemochromatosis
Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?
Hemorrhagic Fever, Crimean
Genetic characterization and molecular clock analyses of the Crimean-Congo hemorrhagic fever virus from human and ticks in India, 2010-2011.
Hemorrhagic Stroke
The Clock Drawing Test as a predictor of cognitive decline in non-demented stroke patients.
Hemorrhoids
Management of internal hemorrhoids by Kshara karma: An educational case report.
Hepatic Encephalopathy
Relationship between clock and star drawing and the degree of hepatic encephalopathy.
Hepatic Encephalopathy
The role of astrocytes in generating circadian rhythmicity in health and disease.
Hepatic Insufficiency
Chronotypology and melatonin alterations in minimal hepatic encephalopathy.
Hepatic Insufficiency
Pituitary hormone circadian rhythm alterations in cirrhosis patients with subclinical hepatic encephalopathy.
Hepatitis
Antituberculosis drug-induced hepatitis: risk factors, prevention and management.
Hepatitis
Circadian rhythms of liver physiology and disease: experimental and clinical evidence.
Hepatitis
Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system.
Hepatitis
Low N-acetyltransferase 2 activity in isoniazid-associated acute hepatitis requiring liver transplantation.
Hepatitis A
Genotype I hepatitis A virus introduction in Italy: Bayesian phylogenetic analysis to date different epidemics.
Hepatitis B
Case studies in orthotopic liver transplantation for hepatitis B: a panel discussion.
Hepatitis B
Hepatitis B virus X protein disrupts the balance of the expression of circadian rhythm genes in hepatocellular carcinoma.
Hepatitis B
Molecular epidemiology of health care-associated transmission of hepatitis B and C viruses.
Hepatitis B
N-Acetyltransferase-2, glutathione S-transferase M1 and T1 genetic polymorphisms, cigarette smoking and hepatocellular carcinoma: a case-control study.
Hepatitis B
Quantitative acetylome analysis reveals histone modifications that may predict prognosis in hepatitis B-related hepatocellular carcinoma.
Hepatitis B
Role of hepatitis B core protein in HBV transcription and recruitment of histone acetyltransferases to cccDNA minichromosome.
Hepatitis B
Role of N-acetyltransferase polymorphisms in hepatitis B related hepatocellular carcinoma: impact of smoking on risk.
Hepatitis C
Analysis of the overdispersed clock in the short-term evolution of hepatitis C virus: Using the E1/E2 gene sequences to infer infection dates in a single source outbreak.
Hepatitis C
Hepatitis C virus evolutionary patterns studied through analysis of full-genome sequences.
Hepatitis C
Inaugural Article: A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades.
Hepatitis C
MicroRNA-10a Impairs Liver Metabolism in Hepatitis C Virus-Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Translocator-Like 1.
Hepatitis C
Molecular analysis of hepatitis C virus infection in Bulgarian injecting drug users.
Hepatitis C
Molecular epidemiology of health care-associated transmission of hepatitis B and C viruses.
Hepatitis C
Spread times of hepatitis C virus estimated by the molecular clock differ among Japan, the United States and Egypt in reflection of their distinct socioeconomic backgrounds.
Hepatitis C
Tracing the evolution of hepatitis C virus in the United States, Japan, and Egypt by using the molecular clock.
Hepatitis C, Chronic
Effects of multiple-dose pegylated interferon alfa-2b on the activity of drug-metabolizing enzymes in persons with chronic hepatitis C.
Hepatitis C, Chronic
The impact of chronic hepatitis C infection on the circadian clock and sleep.
Hepatitis, Chronic
Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system.
Herpes Simplex
A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells.
Herpes Simplex
Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
Herpes Simplex
Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity.
Herpes Simplex
Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter.
Herpes Simplex
Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of ?-Hemoglobinopathies.
Herpes Simplex
Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.
Herpes Simplex
Systemic Immunosuppression in High-Risk Penetrating Keratoplasty: A Systematic Review.
Herpes Simplex
The Histone Acetyltransferase CLOCK Is an Essential Component of the Herpes Simplex Virus 1 Transcriptome That Includes TFIID, ICP4, ICP27, and ICP22.
Herpes Zoster
Diurnal rhythmicity of the canonical clock genes Per1, Per2 and Bmal1 in the rat adrenal gland is unaltered after hypophysectomy.
Herpes Zoster
QUASIMODO, a Novel GPI-anchored zona pellucida protein involved in light input to the Drosophila circadian clock.
Hirschsprung Disease
Rubinstein-Taybi syndrome and Hirschsprung disease in a patient harboring an intragenic deletion of the CREBBP gene.
histone acetyltransferase deficiency
A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy.
histone acetyltransferase deficiency
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination.
histone acetyltransferase deficiency
CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells.
histone acetyltransferase deficiency
Circadian Dysfunction and Obesity: Is Leptin the Missing Link?
histone acetyltransferase deficiency
CREBBP cooperates with the cell cycle machinery to attenuate chidamide sensitivity in relapsed/refractory diffuse large B-cell lymphoma.
histone acetyltransferase deficiency
De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females.
histone acetyltransferase deficiency
Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice.
histone acetyltransferase deficiency
Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation Deficiency.
histone acetyltransferase deficiency
Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis.
histone acetyltransferase deficiency
Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition.
histone acetyltransferase deficiency
Rubinstein-Taybi syndrome and CREBBP c.201 202delTA mutation: a case presenting with varicella meningoencephalitis.
histone acetyltransferase deficiency
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration.
histone acetyltransferase deficiency
The Circadian expression of Piezo1, TRPV4, Connexin26, and VNUT, associated with the expression levels of the clock genes in mouse primary cultured urothelial cells.
histone acetyltransferase deficiency
The circadian rhythm controls telomeres and telomerase activity.
histone acetyltransferase deficiency
The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells.
histone acetyltransferase deficiency
The N-end rule pathway enzyme Naa10 supports epiblast specification in mouse embryonic stem cells by modulating FGF/MAPK.
histone acetyltransferase deficiency
Using VAAST to Identify an X-Linked Disorder Resulting in Lethality in Male Infants Due to N-Terminal Acetyltransferase Deficiency.
histone acetyltransferase deficiency
[Treatment of discoid lupus erythematosus with sulfasalazine: 11 cases]
HIV Infections
Basic science and pathogenesis of ageing with HIV: potential mechanisms and biomarkers.
HIV Infections
Incident infection in high-priority HIV molecular transmission clusters in the United States.
HIV Infections
Validation of molecular clock inferred HIV infection ages: Evidence for accurate estimation of infection dates.
Hodgkin Disease
Chidamide and decitabine can synergistically induce apoptosis of Hodgkin lymphoma cells by up-regulating the expression of PU.1 and KLF4.
Hodgkin Disease
JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte rich large B-cell lymphoma.
Hodgkin Disease
The reciprocal interplay between TNF? and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells.
Huntington Disease
Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease.
Huntington Disease
ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington's disease: a novel approach for cell clock research.
Huntington Disease
Decreased VIP and VPAC2 receptor expression in the biological clock of the R6/2 Huntington's disease mouse.
Huntington Disease
Dietary Restriction and Glycolytic Inhibition Reduce Proteotoxicity and Extend Lifespan via NHR-49.
Huntington Disease
Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Huntington Disease
Epigenetic Changes and Its Intervention in Age-Related Neurodegenerative Diseases.
Huntington Disease
Huntingtin protein: A new option for fixing the Huntington's disease countdown clock.
Huntington Disease
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease.
Huntington Disease
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
Huntington Disease
Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.
Huntington Disease
Partial Depletion of CREB-Binding Protein Reduces Life Expectancy in a Mouse Model of Huntington Disease.
Huntington Disease
Phosphodiesterase type IV inhibition prevents sequestration of CREB binding protein, protects striatal parvalbumin interneurons and rescues motor deficits in the R6/2 mouse model of Huntington's disease.
Huntington Disease
Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease.
Huntington Disease
Screening for cognitive dysfunction in Huntington's disease with the clock drawing test.
Huntington Disease
Sleep and circadian dysfunction in neurodegenerative disorders: insights from a mouse model of Huntington's disease.
Huntington Disease
Striatal modulation of cAMP-response-element-binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington's disease.
Huntington Disease
Suprachiasmatic nucleus neuropeptide expression in patients with Huntington's Disease.
Huntington Disease
The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.
Huntington Disease
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
Hydrocephalus
Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway.
Hyperacusis
Identification of a Circadian Clock in the Inferior Colliculus and Its Dysregulation by Noise Exposure.
Hyperaldosteronism
Hypertension due to loss of clock: novel insight from the molecular analysis of Cry1/Cry2-deleted mice.
Hyperalgesia
Epigenetic regulation of spinal cord gene expression contributes to enhanced postoperative pain and analgesic tolerance subsequent to continuous opioid exposure.
Hyperalgesia
Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain.
Hyperandrogenism
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Hypercholesterolemia
Cholesterol diet enhances daily rhythm of Pai-1 mRNA in the mouse liver.
Hypercholesterolemia
Hypercholesterolemia Among Premature Infarcts: Time to Start the Clock of Familial Hypercholesterolemia Assessment.
Hyperglycemia
A renal genetic risk score (GRS) is associated with kidney dysfunction in people with type 2 diabetes.
Hyperglycemia
Characterization, localization and temporal expression of crustacean hyperglycemic hormone (CHH) in the behaviorally rhythmic peracarid crustaceans, Eurydice pulchra (Leach) and Talitrus saltator (Montagu).
Hyperglycemia
Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats.
Hyperglycemia
DNA Methylation of Five Core Circadian Genes Jointly Contributes to Glucose Metabolism: A Gene-Set Analysis in Monozygotic Twins.
Hyperglycemia
Is common genetic variation at IRS1, ENPP1 and TRIB3 loci associated with cardiometabolic phenotypes in type 2 diabetes? An exploratory analysis of the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 5.
Hyperglycemia
Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in ?-cells.
Hyperglycemia
Melatonin levels in human diabetic dental pulp tissue and its effects on dental pulp cells under hyperglycemic conditions.
Hyperglycemia
miR-150 regulates high glucose-induced cardiomyocyte hypertrophy by targeting the transcriptional co-activator p300.
Hyperglycemia
Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.
Hyperglycemia
PAX6 mutation alters circadian rhythm and ? cell function in mice without affecting glucose tolerance.
Hyperglycemia
Role of High Energy Breakfast "Big Breakfast Diet" in Clock Gene Regulation of Postprandial Hyperglycemia and Weight Loss in Type 2 Diabetes.
Hyperhomocysteinemia
Chronopharmacological targeting of Rev-erb? by puerarin alleviates hyperhomocysteinemia in mice.
Hyperhomocysteinemia
[The role of homocysteine levels in the pathogenesis of cognitive disorders in patients with chronic cerebral ischemia]
Hyperinsulinism
Functional CLOCK Is Not Essentially Associated with Metabolic Disruption Caused by Sleep Phase Feeding in Mice.
Hyperinsulinism
Hyperinsulinism in an individual with an EP300 variant of Rubinstein-Taybi syndrome.
Hyperlipidemias
Circadian rhythms in the CNS and peripheral clock disorders: the circadian clock and hyperlipidemia.
Hyperlipidemias
Effect of hyperlipidemia on the expression of circadian genes in apolipoprotein E knock-out atherosclerotic mice.
Hyperlipidemias
Proxisome proliferator-activated receptor-? mediates high-fat, diet-enhanced daily oscillation of plasminogen activator inhibitor-1 activity in mice.
Hyperlipidemias
[Hyperlipidemia and peroxisome proliferator-activated receptor (PPAR)--regulation of the PPARalpha gene by CLOCK: BMAL1]
Hyperparathyroidism
Changing landscape of the treatment of hyperparathyroidism related to end-stage renal disease-can we turn the clock backward?
Hyperparathyroidism, Secondary
A molecular circadian clock operates in the parathyroid gland and is disturbed in chronic kidney disease associated bone and mineral disorder.
Hyperprolactinemia
A review of dopamine agonist therapy in type 2 diabetes and effects on cardio-metabolic parameters.
Hyperprolactinemia
Effects of the short-acting benzodiazepine triazolam, taken at bedtime, on circadian and sleep-related hormonal profiles in normal men.
Hypersensitivity
A dynamic H3K27ac signature identifies VEGFA-stimulated endothelial enhancers and requires EP300 activity.
Hypersensitivity
A new in vivo model of pantothenate kinase-associated neurodegeneration reveals a surprising role for transcriptional regulation in pathogenesis.
Hypersensitivity
A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.
Hypersensitivity
Acetylator phenotype and genotype in HIV-infected patients with and without sulfonamide hypersensitivity.
Hypersensitivity
Antigen exposure in the late light period induces severe symptoms of food allergy in an OVA-allergic mouse model.
Hypersensitivity
Arylamine N-acetyltransferase (NAT2) gene mutations in children with allergic diseases.
Hypersensitivity
Asymmetric expression level of clock genes in left vs. right nasal mucosa in humans with and without allergies and in rats: Circadian characteristics and possible contribution to nasal cycle.
Hypersensitivity
Circadian regulation of allergic reactions by the mast cell clock in mice.
Hypersensitivity
Circadian Regulation of the Biology of Allergic Disease: Clock Disruption Can Promote Allergy.
Hypersensitivity
Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa.
Hypersensitivity
Controlling the peripheral clock might be a new treatment strategy in allergy and immunology.
Hypersensitivity
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Hypersensitivity
Effect of Circadian Rhythm on Clinical and Pathophysiological Conditions and Inflammation.
Hypersensitivity
Effects of Genetic Polymorphisms of N-Acetyltransferase on Trichloroethylene-Induced Hypersensitivity Dermatitis among Exposed Workers.
Hypersensitivity
Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.
Hypersensitivity
Genotype and phenotype of N-acetyltransferase 2 (NAT2) polymorphism in patients with contact allergy.
Hypersensitivity
Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity.
Hypersensitivity
IgE-dependent activation of human mast cells and fMLP-mediated activation of human eosinophils is controlled by the circadian clock.
Hypersensitivity
Inhibition of IgE-mediated allergic reactions by pharmacologically targeting the circadian clock.
Hypersensitivity
Interacting proteins Rtt109 and Vps75 affect the efficiency of non-homologous end-joining in Saccharomyces cerevisiae.
Hypersensitivity
Lentinan Inhibited the Activation of Th2 Cells in Allergic Mice by Reducing the Amplitude of Changes in Biological Rhythm.
Hypersensitivity
Long-term restricted feeding alters circadian expression and reduces the level of inflammatory and disease markers.
Hypersensitivity
Molecular circadian rhythm shift due to bright light exposure before bedtime is related to subthreshold bipolarity.
Hypersensitivity
N-acetyltransferase 1 and 2 polymorphisms in para-substituted arylamine-induced contact allergy.
Hypersensitivity
Role of the Histone Acetyltransferase Rtt109 in Development and Pathogenicity of the Rice Blast Fungus.
Hypersensitivity
The Mammalian Circadian Clock Exhibits Chronic Ethanol Tolerance and Withdrawal-Induced Glutamate Hypersensitivity, Accompanied by Changes in Glutamate and TrkB Receptor Proteins.
Hypersensitivity
Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients.
Hypersensitivity
[Epigenetic regulation of abiotic stress response in plants to improve the stress tolerance].
Hypertension
About-half-weekly (circasemiseptan) component of the endothelin-1 (ET-1) chronome and vascular disease risk.
Hypertension
Age-associated disruption of molecular clock expression in skeletal muscle of the spontaneously hypertensive rat.
Hypertension
Alterations of circadian expressions of clock genes in Dahl salt-sensitive rats fed a high-salt diet.
Hypertension
Altered expression of norepinephrine transporter participate in hypertension and depression through regulated TNF-? and IL-6.
Hypertension
Assessment of Selected Clock Proteins (CLOCK and CRY1) and Their Relationship with Biochemical, Anthropometric, and Lifestyle Parameters in Hypertensive Patients.
Hypertension
Circadian variations in blood pressure and their implications for the administration of antihypertensive drugs: is dosing in the evening better than in the morning?
Hypertension
Clock genes and salt-sensitive hypertension: a new type of aldosterone-synthesizing enzyme controlled by the circadian clock and angiotensin II.
Hypertension
Common genetic variation in circadian clock genes are associated with cardiovascular risk factors in an African American and Hispanic/Latino cohort.
Hypertension
Different phenotypes of the NAT2 gene influences hydralazine antihypertensive response in patients with resistant hypertension.
Hypertension
Downregulation of Arntl mRNA Expression in Women with Hypertension: A Case-Control Study.
Hypertension
Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort.
Hypertension
Exercise-induced arterial hypertension - an independent factor for hypertrophy and a ticking clock for cardiac fatigue or atrial fibrillation in athletes?
Hypertension
Expression of circadian rhythm genes CLOCK, BMAL1, and PER1 in buccal epithelial cells of patients with essential arterial hypertension in dependence on polymorphic variants of CLOCK and BMAL1 genes.
Hypertension
Female C57BL/6J mice lacking the circadian clock protein PER1 are protected from nondipping hypertension.
Hypertension
Gene-gene interaction between serotonin transporter (SLC6A4) and clock modulates the risk of metabolic syndrome in rotating shiftworkers.
Hypertension
High Fat Diets Sex-Specifically Affect the Renal Transcriptome and Program Obesity, Kidney Injury, and Hypertension in the Offspring.
Hypertension
Hormones and the autonomic nervous system are involved in suprachiasmatic nucleus modulation of glucose homeostasis.
Hypertension
Hypertension due to loss of clock: novel insight from the molecular analysis of Cry1/Cry2-deleted mice.
Hypertension
Identification of Clock Genes Related to Hypertension in Kidney From Spontaneously Hypertensive Rats.
Hypertension
Influence of ApoE Genotype and Clock T3111C Interaction with Cardiovascular Risk Factors on the Progression to Alzheimer's Disease in Subjective Cognitive Decline and Mild Cognitive Impairment Patients.
Hypertension
Knockout of the circadian clock protein PER1 results in sex-dependent alterations of ET-1 production in mice in response to a high-salt diet plus mineralocorticoid treatment.
Hypertension
Lysine Acetyltransferases CBP and p300 Attenuate Transcriptional Activity of the Mineralocorticoid Receptor through its Acetylation.
Hypertension
MicroRNAs: a potential interface between the circadian clock and human health.
Hypertension
Neuropeptide changes in the suprachiasmatic nucleus in primary hypertension indicate functional impairment of the biological clock.
Hypertension
OS 33-09 ASSOCIATION OF CLOCK GENE POLYMORPHISM WITH INSULIN RESISTANCE IN HYPERTENSION: A CASE-CONTROL STUDY.
Hypertension
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Hypertension
Renal Na Handling Defect Associated with PER1-Dependent Non-Dipping Hypertension In Male Mice.
Hypertension
Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
Hypertension
The clock is ticking: the case for achieving more rapid control of hypertension.
Hypertension
The rationale and design of the antihypertensives and vascular, endothelial, and cognitive function (AVEC) trial in elderly hypertensives with early cognitive impairment: Role of the renin angiotensin system inhibition.
Hypertension
Thousands of blood pressure and heart rate measurements at fixed clock hours may mislead.
Hypertension
Time-Restricted G-Protein Signaling Pathways via GPR176, Gz, and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus.
Hypertension
[Association of T3111C polymorphism in 3'-untranslated region of the CLOCK gene with the risk of essential arterial hypertension and coronary artery disease in the Russian population Karelia].
Hypertension, Portal
Correlation Between NAT2 Gene Polymorphism and Cirrhotic Portal Hypertension in the Chinese Population.
Hyperthyroidism
Disruption of the pituitary circadian clock induced by hypothyroidism and hyperthyroidism: consequences on daily pituitary hormone expression profiles.
Hyperthyroidism
[Acetylation phenotype and the changes in selected indicators of calcium-phosphate metabolism in patients with hyperthyroidism treated with propranolol]
Hypertriglyceridemia
Novel peroxisome proliferator-activated receptor (PPAR) gamma and PPARdelta ligands produce distinct biological effects.
Hyphema
Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes: The ABCDEF Guide.
Hyphema
Scleral and corneal laceration with iris prolapse caused by an eagle claw.
Hypoglycemia
American College of Physicians diabetes guidelines attempt to turn back the clock, conflating good HbA1c with hypoglycemia.
Hypotension
Case studies in orthotopic liver transplantation for hepatitis B: a panel discussion.
Hypotension
Circadian rhythm in hypotensive effect of sodium nitroprusside in rats and its relevance to sympathetic nervous activity.
Hypotension
Conventional and ambulatory blood pressure measurement in older patients with isolated systolic hypertension:second progress report on the ambulatory blood pressure monitoring project in the Syst-Eur trial.
Hypothyroidism
Disruption of the pituitary circadian clock induced by hypothyroidism and hyperthyroidism: consequences on daily pituitary hormone expression profiles.
Hypothyroidism
Effects of inhibition of thyroid function and of cold on melatonin synthesis and porphyrin content in the Harderian glands of male Syrian hamsters, Mesocricetus auratus.
Hypothyroidism
[Effect of experimental hypothyroidism on N-acetyltransferase activity in the rat liver]
Hypoventilation
Effect of reoxygenation on the electrical stability of the rat heart in vivo: a chronobiological study.
Hypoxia, Brain
Expression of Clock genes in the pineal glands of newborn rats with hypoxic-ischemic encephalopathy.
Hypoxia-Ischemia, Brain
Expression of Clock genes in the pineal glands of newborn rats with hypoxic-ischemic encephalopathy.
Idiopathic Hypersomnia
Altered dynamics in the circadian oscillation of clock genes in dermal fibroblasts of patients suffering from idiopathic hypersomnia.
Idiopathic Pulmonary Fibrosis
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis
Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo.
Illusions
Motion illusions in optical art presented for long durations are temporally distorted.
Illusions
Neural Repetition Suppression Modulates Time Perception: Evidence From Electrophysiology and Pupillometry.
Illusions
On the relation between body ownership and sense of agency: A link at the level of sensory-related signals.
Illusions
Temporal data representation, normalization, extraction, and reasoning: A review from clinical domain.
Illusions
Ticks per thought or thoughts per tick? A selective review of time perception with hints on future research.
Immune System Diseases
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening.
Immune System Diseases
Stress and glucocorticoid receptor transcriptional programming in time and space: Implications for the brain-gut axis.
Infections
A Localized Pseudomonas syringae Infection Triggers Systemic Clock Responses in Arabidopsis.
Infections
Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus.
Infections
Alteration of microRNA-4474/4717 expression and CREB-binding protein in human colorectal cancer tissues infected with Fusobacterium nucleatum.
Infections
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Infections
Analysis of the overdispersed clock in the short-term evolution of hepatitis C virus: Using the E1/E2 gene sequences to infer infection dates in a single source outbreak.
Infections
Bacterial Infection Disrupts Clock Gene Expression to Attenuate Immune Responses.
Infections
Bayesian skyline plot inference of the Toscana virus epidemic: a decline in the effective number of infections over the last 30 years.
Infections
Bovine herpesvirus 1 immediate-early protein (bICP0) interacts with the histone acetyltransferase p300, which stimulates productive infection and gC promoter activity.
Infections
Can Better Management of Periodontal Disease Delay the Onset and Progression of Alzheimer's Disease?
Infections
Characterisation of a SAT-1 outbreak of foot-and-mouth disease in captive African buffalo (Syncerus caffer): clinical symptoms, genetic characterisation and phylogenetic comparison of outbreak isolates.
Infections
Circadian clock components Bmal1 and Clock1 regulate tlr9 gene expression in the Japanese medaka (Oryzias latipes).
Infections
Circadian regulation in the ability of Drosophila to combat pathogenic infections.
Infections
Clinical evidence that the pandemic from 1889 to 1891 commonly called the Russian flu might have been an earlier coronavirus pandemic.
Infections
Clock gene expression during chronic inflammation induced by infection with Trypanosoma brucei brucei in rats.
Infections
Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
Infections
Defence responses of Arabidopsis thaliana to infection by Pseudomonas syringae are regulated by the circadian clock.
Infections
Differential control of pre-invasive and post-invasive antibacterial defense by the Arabidopsis circadian clock.
Infections
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe.
Infections
Dysregulation of photic induction of Fos-related protein in the biological clock during experimental trypanosomiasis.
Infections
Earlier treatment initiation is associated with a decreased number of HIV-1 subtype A1 transmissions in Greece.
Infections
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
Infections
Effect of Circadian Rhythm on Clinical and Pathophysiological Conditions and Inflammation.
Infections
Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHV.
Infections
Epigenetic reader BRD4 supports mycobacterial pathogenesis by co-modulating host lipophagy and angiogenesis.
Infections
Evidence for a new contiguous gene syndrome, the chromosome 16p13.3 deletion syndrome alias severe Rubinstein-Taybi syndrome.
Infections
Evolutionary and molecular analysis of the emergent severe fever with thrombocytopenia syndrome virus.
Infections
Experimental infection of gnotobiotic piglets with Escherichia coli strains positive for EAST1 and AIDA.
Infections
From trypanosomes to the nervous system, from molecules to behavior: a survey, on the occasion of the 90th anniversary of Castellani's discovery of the parasites in sleeping sickness.
Infections
Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus.
Infections
Herpes Simplex Virus 1-Encoded Tegument Protein VP16 Abrogates the Production of Beta Interferon (IFN) by Inhibiting NF-?B Activation and Blocking IFN Regulatory Factor 3 To Recruit Its Coactivator CBP.
Infections
Histone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway.
Infections
Histone acetylation and flagellin are essential for Legionella pneumophila-induced cytokine expression.
Infections
Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes.
Infections
Hydrophobin CmHYD1 Is Involved in Conidiation, Infection and Primordium Formation, and Regulated by GATA Transcription Factor CmAreA in Edible Fungus, Cordyceps militaris.
Infections
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Infections
Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.
Infections
Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi's Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells.
Infections
Jasmonate signalling drives time-of-day differences in susceptibility of Arabidopsis to the fungal pathogen Botrytis cinerea.
Infections
Lights, Rhythms, Infection: The Role of Light and the Circadian Clock in Determining the Outcome of Plant-Pathogen Interactions.
Infections
Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection.
Infections
Loss of circadian protection against influenza infection in adult mice exposed to hyperoxia as neonates.
Infections
Lysine acetylation as drug target in fungi: an underexplored potential in Aspergillus spp.
Infections
N-acetyltransferase 2 polymorphism in patients infected with human immunodeficiency virus.
Infections
Nighttime activities and peripheral clock oscillations depend on Wolbachia endosymbionts in flies.
Infections
NPR1 and Redox Rhythmx: Connections, between Circadian Clock and Plant Immunity.
Infections
Nuclear receptor REV-ERB? mediates circadian sensitivity to mortality in murine vesicular stomatitis virus-induced encephalitis.
Infections
Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents.
Infections
Persistent human Borna disease virus infection modifies the acetylome of human oligodendroglia cells towards higher energy and transporter levels.
Infections
Phylogenetic reconstruction of a known HIV-1 CRF04_cpx transmission network using maximum likelihood and Bayesian methods.
Infections
Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection.
Infections
Regulated nuclear-cytoplasmic localization of interferon regulatory factor 3, a subunit of double-stranded RNA-activated factor 1.
Infections
Relative importance of heat-labile enterotoxin in the causation of severe diarrheal disease in the gnotobiotic piglet model by a strain of enterotoxigenic Escherichia coli that produces multiple enterotoxins.
Infections
Safety issues associated with dietary management in patients with hepatic glycogen storage disease.
Infections
Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change.
Infections
Sleep and timekeeping changes, and dysregulation of the biological clock in experimental trypanosomiasis.
Infections
Sleep triggered by an immune response in Drosophila is regulated by the circadian clock and requires the NFkappaB Relish.
Infections
Spread times of hepatitis C virus estimated by the molecular clock differ among Japan, the United States and Egypt in reflection of their distinct socioeconomic backgrounds.
Infections
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Infections
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.
Infections
Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.
Infections
The Biological Significance of Targeting Acetylation-Mediated Gene Regulation for Designing New Mechanistic Tools and Potential Therapeutics.
Infections
The circadian clock in immune cells controls the magnitude of Leishmania parasite infection.
Infections
The circadian clock Period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock.
Infections
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock.
Infections
The effect of Wolbachia on diapause, fecundity, and clock gene expression in Trichogramma brassicae (Hymenoptera: Trichogrammatidae).
Infections
The Effects of Anti-retroviral Therapy on Epigenetic Age Acceleration Observed in HIV-1-infected Adults.
Infections
The effects of SP110's associated genes on fresh cavitary pulmonary tuberculosis in Han Chinese population.
Infections
The Fungi-specific histone Acetyltransferase Rtt109 mediates morphogenesis, Aflatoxin synthesis and pathogenicity in Aspergillus flavus by acetylating H3K9.
Infections
The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF.
Infections
The innate immune cell response to bacterial infection in larval zebrafish is light-regulated.
Infections
The International Dimension of the U.S. HIV Transmission Network and Onward Transmission of HIV Recently Imported into the United States.
Infections
The Involvement of Histone H3 Acetylation in Bovine Herpesvirus 1 Replication in MDBK Cells.
Infections
The rise of superbugs. Dangerous infections that are resistant to antibiotics are spreading and growing stronger, with dire consequences. Medical experts say it's a mess of our own making--and the clock is ticking on when and how we must solve it. The first in a three-part series.
Infections
Tracing the evolution of hepatitis C virus in the United States, Japan, and Egypt by using the molecular clock.
Infections
Transcriptomic response to parasite infection in Nile tilapia (Oreochromis niloticus) depends on rearing density.
Infections
Validation of molecular clock inferred HIV infection ages: Evidence for accurate estimation of infection dates.
Infections
VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection.
Infections
What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired?
Infertility
Association of CLOCK gene variants with semen quality in idiopathic infertile Han-Chinese males.
Infertility
Bisphenol A attenuates testosterone production in Leydig cells via the inhibition of NR1D1 signaling.
Infertility
Cited2 protein level in cumulus cells is a biomarker for human embryo quality and pregnancy outcome in one in vitro fertilization cycle.
Infertility
Conditional Deletion of Bmal1 in Ovarian Theca Cells Disrupts Ovulation in Female Mice.
Infertility
Involvement of the luteinizing hormone surge in the regulation of ovary and oviduct clock gene expression in mice.
Infertility
Recovery from Age-Related Infertility under Environmental Light-Dark Cycles Adjusted to the Intrinsic Circadian Period.
Infertility
Rethinking the biological clock: eleventh-hour moms, miracle moms and meanings of age-related infertility.
Infertility
Sterility assurance. Clock is ticking to replace STERIS SS1 units--are hospitals ready? Interview by Jeff Ferenc.
Infertility
The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge.
Infertility
Variants of the CLOCK gene affect the risk of idiopathic male infertility in the Han-Chinese population.
Infertility, Male
Bovine Circadian Locomotor Output Cycles Kaput (CLOCK) and Clusterin (CLU) mRNA Quantitation in Ejaculated Crossbred Bull Spermatozoa.
Infertility, Male
Genetic Variation in Circadian Rhythm Genes CLOCK and ARNTL as Risk Factor for Male Infertility.
Infertility, Male
Synergism between the N-acetyltransferase 2 gene and oxidant exposure increases the risk of idiopathic male infertility.
Infertility, Male
Variants of the CLOCK gene affect the risk of idiopathic male infertility in the Han-Chinese population.
Infertility, Male
[Single nucleotide polymorphisms of the N-acetyltransferase 2 gene not correlated with male infertility].
Inflammatory Bowel Diseases
Association Study of a Polymorphism in Clock Gene PERIOD3 and Risk of Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.
Inflammatory Bowel Diseases
Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer.
Inflammatory Bowel Diseases
Clock Gene Disruption is an Initial Manifestation of Inflammatory Bowel Disease.
Inflammatory Bowel Diseases
Common polymorphisms in the microsomal epoxide hydrolase and N-acetyltransferase 2 genes in association with inflammatory bowel disease in the Danish population.
Inflammatory Bowel Diseases
Dysregulated Lysine Acetyltransferase 2B Promotes Inflammatory Bowel Disease Pathogenesis Through Transcriptional Repression of Interleukin-10.
Inflammatory Bowel Diseases
N-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulphasalazine in the treatment of inflammatory bowel disease.
Inflammatory Bowel Diseases
Neonatal Exposures and Risk of Inflammatory Bowel Disease: When Does the Clock Start Ticking?
Inflammatory Bowel Diseases
STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease.
Inflammatory Bowel Diseases
The Role of N-Acetyltransferase 2 Polymorphism in the Etiopathogenesis of Inflammatory Bowel Disease.
Influenza, Human
A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-? Production.
Influenza, Human
Acetylation of the influenza A virus polymerase subunit PA in the N-terminal domain positively regulates its endonuclease activity.
Influenza, Human
BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Influenza, Human
C646, a Novel p300/CREB-Binding Protein-Specific Inhibitor of Histone Acetyltransferase, Attenuates Influenza A Virus Infection.
Influenza, Human
Cell autonomous regulation of herpes and influenza virus infection by the circadian clock.
Influenza, Human
Histone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway.
Influenza, Human
Influenza A virus nucleoprotein is acetylated by histone acetyltransferases, PCAF and GCN5.
Influenza, Human
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Influenza, Human
Novel non-parametric models to estimate evolutionary rates and divergence times from heterochronous sequence data.
Insulin Resistance
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Insulin Resistance
Aryl Hydrocarbon Receptor Deficiency Enhances Insulin Sensitivity and Reduces PPAR-? Pathway Activity in Mice.
Insulin Resistance
Association of insulin resistance with polymorphic variants of Clock and Bmal1 genes: A case-control study.
Insulin Resistance
Associations of Plasma BACE1 Level and BACE1 C786G Gene Polymorphism with Cognitive Functions in Patients with Type 2 Diabetes: A Cross- Sectional Study.
Insulin Resistance
Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome.
Insulin Resistance
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis.
Insulin Resistance
Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice.
Insulin Resistance
Cardiac Autonomic Neuropathy in Diabetes: A Predictor of Cardiometabolic Events.
Insulin Resistance
Chronic circadian shift leads to adipose tissue inflammation and fibrosis.
Insulin Resistance
Circadian misalignment disturbs the skeletal muscle lipidome in healthy young men.
Insulin Resistance
Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle.
Insulin Resistance
Circadian rhythms, metabolism, and insulin sensitivity: transcriptional networks in animal models.
Insulin Resistance
Circadian Transcription from Beta Cell Function to Diabetes Pathophysiology.
Insulin Resistance
Circulating Exosomal miRNAs Signal Circadian Misalignment to Peripheral Metabolic Tissues.
Insulin Resistance
CLOCK and BMAL1 regulate muscle insulin sensitivity via SIRT1 in male mice.
Insulin Resistance
Clock Genes, Inflammation and the Immune System-Implications for Diabetes, Obesity and Neurodegenerative Diseases.
Insulin Resistance
CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity via SIRT1.
Insulin Resistance
Cortisol Circadian Rhythm and Insulin Resistance in Muscle: Effect of Dosing and Timing of Hydrocortisone Exposure on Insulin Sensitivity in Synchronized Muscle Cells.
Insulin Resistance
Decreased brain and muscle ARNT-like protein 1 expression mediated the contribution of hyperandrogenism to insulin resistance in polycystic ovary syndrome.
Insulin Resistance
Diabetes and atherothrombosis: The circadian rhythm and role of melatonin in vascular protection.
Insulin Resistance
Diet-induced insulin resistance state disturbs brain clock processes and alters tuning of clock outputs in the Sand rat, Psammomys obesus.
Insulin Resistance
Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing.
Insulin Resistance
Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm.
Insulin Resistance
EGCG Ameliorates Insulin Resistance and Mitochondrial Dysfunction in HepG2 Cells: Involvement of Bmal1.
Insulin Resistance
Evidence-based practice use of quick-release bromocriptine across the natural history of type 2 diabetes mellitus.
Insulin Resistance
Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes.
Insulin Resistance
Expression of clock gene Dbp in omental and mesenteric adipose tissue in patients with type 2 diabetes.
Insulin Resistance
Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects.
Insulin Resistance
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration.
Insulin Resistance
High fat diet induced abnormalities in metabolism, growth, behavior, and circadian clock in Drosophila melanogaster.
Insulin Resistance
Hypothalamic control of energy metabolism via the autonomic nervous system.
Insulin Resistance
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.
Insulin Resistance
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Insulin Resistance
Induction of Dbp by a histone deacetylase inhibitor is involved in amelioration of insulin sensitivity via adipocyte differentiation in ob/ob mice.
Insulin Resistance
Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression.
Insulin Resistance
Is exercise a viable therapeutic intervention to mitigate mitochondrial dysfunction and insulin resistance induced by sleep loss?
Insulin Resistance
Later chronotype is associated with higher hemoglobin A1c in prediabetes patients.
Insulin Resistance
Light therapy for better mood and insulin sensitivity in patients with major depression and type 2 diabetes: a randomised, double-blind, parallel-arm trial.
Insulin Resistance
Loss of circadian rhythm of circulating insulin concentration induced by high-fat diet intake is associated with disrupted rhythmic expression of circadian clock genes in the liver.
Insulin Resistance
Metabolic-sensing of the skeletal muscle clock coordinates fuel oxidation.
Insulin Resistance
Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock.
Insulin Resistance
Muscle-specific loss of Bmal1 leads to disrupted tissue glucose metabolism and systemic glucose homeostasis.
Insulin Resistance
Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance.
Insulin Resistance
Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice.
Insulin Resistance
Night-restricted feeding improves locomotor activity rhythm and modulates nutrient utilization to accelerate growth in rabbits.
Insulin Resistance
Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes.
Insulin Resistance
Novel association between the nonsynonymous A803G polymorphism of the N-acetyltransferase 2 gene and impaired glucose homeostasis in obese children and adolescents.
Insulin Resistance
Nuclear receptors as targets for drug development: molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin.
Insulin Resistance
OS 33-09 ASSOCIATION OF CLOCK GENE POLYMORPHISM WITH INSULIN RESISTANCE IN HYPERTENSION: A CASE-CONTROL STUDY.
Insulin Resistance
Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview.
Insulin Resistance
Reduced caloric intake and periodic fasting independently contribute to metabolic effects of caloric restriction.
Insulin Resistance
Reduction of mNAT1/hNAT2 Contributes to Cerebral Endothelial Necroptosis and A? Accumulation in Alzheimer's Disease.
Insulin Resistance
Retinoic acid-related orphan receptor ? (ROR?): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity.
Insulin Resistance
REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity.
Insulin Resistance
Role of High Energy Breakfast "Big Breakfast Diet" in Clock Gene Regulation of Postprandial Hyperglycemia and Weight Loss in Type 2 Diabetes.
Insulin Resistance
Rosiglitazone reverses high fat diet-induced changes in BMAL1 function in muscle, fat, and liver tissue in mice.
Insulin Resistance
Shift work cycle-induced alterations of circadian rhythms potentiate the effects of high fat diet on inflammation and metabolism.
Insulin Resistance
Suprachiasmatic nucleus neuropeptides and their control of endogenous glucose production.
Insulin Resistance
The Circadian Clock, Shift Work, and Tissue-Specific Insulin Resistance.
Insulin Resistance
The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism.
Insulin Resistance
The suprachiasmatic nucleus controls circadian energy metabolism and hepatic insulin sensitivity.
Insulin Resistance
TRPV1 participates in the activation of clock molecular machinery in the brown adipose tissue in response to light-dark cycle.
Insulinoma
cAMP opposes the glucose-mediated induction of the L-PK gene by preventing the recruitment of a complex containing ChREBP, HNF4{alpha}, and CBP.
Intellectual Disability
A Novel De Novo Frameshift Mutation in KAT6A Identified by Whole Exome Sequencing.
Intellectual Disability
A Novel Frameshift Mutation in KAT6A Is Associated with Pancraniosynostosis.
Intellectual Disability
A novel NAA10 p.(R83H) variant with impaired acetyltransferase activity identified in two boys with ID and microcephaly.
Intellectual Disability
A novel NAA10 variant with impaired acetyltransferase activity causes developmental delay, intellectual disability, and hypertrophic cardiomyopathy.
Intellectual Disability
A novel truncating variant within exon 7 of KAT6B associated with features of both Say-Barber-Bieseker-Young-Simpson syndrome and genitopatellar syndrome: Further evidence of a continuum in the clinical spectrum of KAT6B-related disorders.
Intellectual Disability
Analysis of mutations within the intron20 splice donor site of CREBBP in patients with and without classical RSTS.
Intellectual Disability
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
Intellectual Disability
CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.
Intellectual Disability
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.
Intellectual Disability
Clinical Manifestations in a Girl with NAA10-Related Syndrome and Genotype-Phenotype Correlation in Females.
Intellectual Disability
Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.
Intellectual Disability
Confirmation of a new phenotype in an individual with a variant in the last part of exon 30 of CREBBP.
Intellectual Disability
Confirmation of EP300 gene mutations as a rare cause of Rubinstein-Taybi syndrome.
Intellectual Disability
De novo mutations in the SET nuclear proto-oncogene, encoding a component of the inhibitor of histone acetyltransferases (INHAT) complex in patients with nonsyndromic intellectual disability.
Intellectual Disability
Dominant Mutations in KAT6A Cause Intellectual Disability with Recognizable Syndromic Features.
Intellectual Disability
Duplication 16p13.3 and the CREBBP gene: confirmation of the phenotype.
Intellectual Disability
Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation Deficiency.
Intellectual Disability
Five new cases of syndromic intellectual disability due to KAT6A mutations: widening the molecular and clinical spectrum.
Intellectual Disability
Further delineation of the KAT6B molecular and phenotypic spectrum.
Intellectual Disability
Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A?>?T, p.(Lys1277*).
Intellectual Disability
Generation of three iPSC lines (IAIi002, IAIi004, IAIi003) from Rubinstein-Taybi syndrome 1 patients carrying CREBBP non sense c.4435G>T, p.(Gly1479*) and c.3474G>A, p.(Trp1158*) and missense c.4627G>T, p.(Asp1543Tyr) mutations.
Intellectual Disability
Genetic and clinical heterogeneity in Korean patients with Rubinstein-Taybi syndrome.
Intellectual Disability
Identifying the KAT6B Mutation via Diagnostic Exome Sequencing to Diagnose Say-Barber-Biesecker-Young-Simpson Syndrome in Three Generations of a Family.
Intellectual Disability
Impaired Regulation of Histone Methylation and Acetylation Underlies Specific Neurodevelopmental Disorders.
Intellectual Disability
iPSC-derived neurons of CREBBP- and EP300-mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability.
Intellectual Disability
Kat6b Modulates Oct4 and Nanog Binding to Chromatin in Embryonic Stem Cells and Is Required for Efficient Neural Differentiation.
Intellectual Disability
Knowledge of results and learning to tell the time in an adult male with an intellectual disability: a single-subject research design.
Intellectual Disability
Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability.
Intellectual Disability
Missense NAA20 variants impairing the NatB protein N-terminal acetyltransferase cause autosomal recessive developmental delay, intellectual disability, and microcephaly.
Intellectual Disability
Missense Variants in the Histone Acetyltransferase Complex Component Gene TRRAP Cause Autism and Syndromic Intellectual Disability.
Intellectual Disability
MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease.
Intellectual Disability
Mutations in Histone Acetylase Modifier BRPF1 Cause an Autosomal-Dominant Form of Intellectual Disability with Associated Ptosis.
Intellectual Disability
NAA10 dysfunction with normal NatA-complex activity in a girl with non-syndromic ID and a de novo NAA10 p.(V111G) variant - a case report.
Intellectual Disability
NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment.
Intellectual Disability
Novel Causative Variants in DYRK1A, KARS, and KAT6A Associated with Intellectual Disability and Additional Phenotypic Features.
Intellectual Disability
Paroxysmal Movement Disorder and Epilepsy Caused by a De Novo Truncating Mutation in KAT6A.
Intellectual Disability
Severe syndromic ID and skewed X-inactivation in a girl with NAA10 dysfunction and a novel heterozygous de novo NAA10 p.(His16Pro) variant - a case report.
Intellectual Disability
Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome.
Intellectual Disability
Temporal requirements of the fragile x mental retardation protein in modulating circadian clock circuit synaptic architecture.
Intellectual Disability
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Intellectual Disability
Three brothers with a nonsense mutation in KAT6A caused by parental germline mosaicism.
Intellectual Disability
Transcriptome Analysis of iPSC-Derived Neurons from Rubinstein-Taybi Patients Reveals Deficits in Neuronal Differentiation.
Intervertebral Disc Degeneration
The circadian rhythm in intervertebral disc degeneration: an autophagy connection.
Intestinal Pseudo-Obstruction
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Intestinal Volvulus
Putrescine N-acetyltransferase in Onchocerca volvulus and Ascaris suum, an enzyme which is involved in polyamine degradation and release of N-acetylputrescine.
Intracranial Hemorrhages
Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein.
Iron Deficiencies
Comprehensive mapping of abiotic stress inputs into the soybean circadian clock.
Iron Deficiencies
Iron Deficiency Reduces Synapse Formation in the Drosophila Clock Circuit.
Ischemic Stroke
Caring for stroke survivors: baseline and 1-year determinants of caregiver burden.
Ischemic Stroke
Circadian rhythms of melatonin, cortisol, and clock gene expression in the hyperacute phase of wake-up stroke: study design and measurement.
Ischemic Stroke
Collateral status as the fifth dimension: warping the time clock for endovascular treatment in acute ischaemic stroke.
Ischemic Stroke
Daylight saving time and the incidence of thrombolysis to treat acute ischemic stroke.
Ischemic Stroke
Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke?
Ischemic Stroke
Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.
Ischemic Stroke
Particulate Air Pollution, Clock Gene Methylation, and Stroke: Effects on Stroke Severity and Disability.
Ischemic Stroke
The Circadian Clock, the Brain, and COVID-19: The Cases of Olfaction and the Timing of Sleep.
Ischemic Stroke
Time-of-Day Dependent Neuronal Injury After Ischemic Stroke: Implication of Circadian Clock Transcriptional Factor Bmal1 and Survival Kinase AKT.
Ischemic Stroke
We are on the clock: MRI as a surrogate marker of lesion age in acute ischemic stroke.
Ischemic Stroke
[Transient ischemic attacks and prolonged reversible ischemic neurologic deficit. Diagnosis, differential diagnosis and treatment]
Jet Lag Syndrome
Accelerating recovery from jet lag: prediction from a multi-oscillator model and its experimental confirmation in model animals.
Jet Lag Syndrome
Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag.
Jet Lag Syndrome
Amplitude Effects Allow Short Jet Lags and Large Seasonal Phase Shifts in Minimal Clock Models.
Jet Lag Syndrome
Arginine vasopressin signaling in the suprachiasmatic nucleus on the resilience of circadian clock to jet lag.
Jet Lag Syndrome
BMAL1 links the circadian clock to viral airway pathology and asthma phenotypes.
Jet Lag Syndrome
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Jet Lag Syndrome
Chronotype and stability of spontaneous locomotor activity rhythm in BMAL1-deficient mice.
Jet Lag Syndrome
Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer.
Jet Lag Syndrome
Circadian disruption and remedial interventions: effects and interventions for jet lag for athletic peak performance.
Jet Lag Syndrome
Critical phase shifts slow down circadian clock recovery: implications for jet lag.
Jet Lag Syndrome
Differential resynchronisation of circadian clock gene expression within the suprachiasmatic nuclei of mice subjected to experimental jet lag.
Jet Lag Syndrome
Disruption of adolescents' circadian clock: The vicious circle of media use, exposure to light at night, sleep loss and risk behaviors.
Jet Lag Syndrome
Effect of BRAND's Essence of Chicken on the resetting process of circadian clocks in rats subjected to experimental jet lag.
Jet Lag Syndrome
Effect of Daily Light on c-Fos Expression in the Suprachiasmatic Nucleus under Jet Lag Conditions.
Jet Lag Syndrome
Effect of regular and irregular stimulation cycles of dexamethasone on circadian clock in NIH3T3 cells.
Jet Lag Syndrome
Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice.
Jet Lag Syndrome
Effects of light and food schedules on liver and tumor molecular clocks in mice.
Jet Lag Syndrome
Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition.
Jet Lag Syndrome
Even a stopped clock tells the right time twice a day: circadian timekeeping in Drosophila.
Jet Lag Syndrome
Evening and night exposure to screens of media devices and its association with subjectively perceived sleep: Should "light hygiene" be given more attention?
Jet Lag Syndrome
From circadian clock mechanism to sleep disorders and jet lag: Insights from a computational approach.
Jet Lag Syndrome
Identifying some determinants of "jet lag" and its symptoms: a study of athletes and other travellers.
Jet Lag Syndrome
Insomnia, biological clock, and the bedtime decision: an economic perspective.
Jet Lag Syndrome
Jet lag and shift work sleep disorders: how to help reset the internal clock.
Jet Lag Syndrome
Light entrainment of the SCN circadian clock and implications for personalized alterations of corticosterone rhythms in shift work and jet lag.
Jet Lag Syndrome
Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease.
Jet Lag Syndrome
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
Jet Lag Syndrome
Modeling and analysis of the impacts of jet lag on circadian rhythm and its role in tumor growth.
Jet Lag Syndrome
Modeling the circadian clock: from molecular mechanism to physiological disorders.
Jet Lag Syndrome
Novel insights from genetic and molecular characterization of the human clock.
Jet Lag Syndrome
Rapid phase adjustment of melatonin and core body temperature rhythms following a 6-h advance of the light/dark cycle in the horse.
Jet Lag Syndrome
The Cancer Clock Is (Not) Ticking: Links between Circadian Rhythms and Cancer.
Jet Lag Syndrome
The Circadian System: A Regulatory Feedback Network of Periphery and Brain.
Jet Lag Syndrome
The effect of L-carnosine on the circadian resetting of clock genes in the heart of rats.
Jet Lag Syndrome
Transgenic rats expressing dominant negative BMAL1 showed circadian clock amplitude reduction and rapid recovery from jet lag.
Jet Lag Syndrome
Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis.
Jet Lag Syndrome
[Molecular and Neural Mechanisms for the Robustness of the Circadian Clock].
Joint Diseases
Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice.
Joint Diseases
Running on time: the role of circadian clocks in the musculoskeletal system.
Joint Diseases
Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival.
Keratitis
Insect wing tarsal foreign body causing conjunctival granuloma and marginal keratitis.
Keratosis, Actinic
Expression of p300 and p300/CBP associated factor (PCAF) in actinic keratosis and squamous cell carcinoma of the skin.
Kidney Diseases
Mechanism of circadian regulation of the NRF2/ARE pathway in renal ischemia-reperfusion.
Kidney Diseases
Predicted Effect of Circadian Clock Modulation of NHE3 of a Proximal Tubule Cell on Sodium Transport.
Kidney Failure, Chronic
Diastolic dysfunction in end-stage renal disease patient: what the ticking clock has told us?
Kidney Failure, Chronic
IMMUNOGENETIC AND PHARMACOCHEMICAL CHARACTERIZATION OF THE ABO SYSTEM GLYCOPROTEIN PROPERTIES AS CRITERIA OF INDIVIDUAL SENSITIVITY TO ANTITUMOR AGENT BORTEZOMIB IN THE PLASMA CELL MYELOMA PATIENTS.
Kidney Neoplasms
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.
Kidney Neoplasms
The role of vascular clamping during robot-assisted partial nephrectomy for localized renal cancer: rationale and design of the CLOCK randomized phase III study.
Laminopathies
Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression.
Language Development Disorders
A Novel Frameshift Mutation in KAT6A Is Associated with Pancraniosynostosis.
Language Development Disorders
Five new cases of syndromic intellectual disability due to KAT6A mutations: widening the molecular and clinical spectrum.
Language Development Disorders
Three brothers with a nonsense mutation in KAT6A caused by parental germline mosaicism.
Language Development Disorders
Truncating SRCAP variants outside the Floating-Harbor syndrome locus cause a distinct neurodevelopmental disorder with a specific DNA methylation signature.
Laryngomalacia
A Say-Barber-Biesecker-Young-Simpson variant of Ohdo syndrome with a KAT6B 10-base pair palindromic duplication: A recurrent mutation causing a severe phenotype mixed with genitopatellar syndrome.
Learning Disabilities
Novel insights from genetic and molecular characterization of the human clock.
Leiomyoma
Leiomyoma with KAT6B-KANSL1 fusion: case report of a rapidly enlarging uterine mass in a postmenopausal woman.
Leiomyoma
Ovarian steroid hormones modulate the expression of progesterone receptors and histone acetylation patterns in uterine leiomyoma cells.
Leiomyosarcoma
Synergistic effects of pazopanib and hyperthermia against uterine leiomyosarcoma growth mediated by downregulation of histone acetyltransferase 1.
Leishmaniasis, Visceral
The biological clock of an hematophagous insect: locomotor activity rhythms, circadian expression and downregulation after a blood meal.
Lens Subluxation
Assessment of the safety and efficacy of primary retropupillary fixation of iris-claw intraocular lenses in children with large lens subluxations.
Lens Subluxation
Evaluation of functional outcome and stability of sutureless scleral tunnel fixated IOLs in children with ectopia lentis.
Leukemia
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Leukemia
A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
Leukemia
A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells.
Leukemia
Acute mixed lineage leukemia with an inv(8)(p11q13) resulting in fusion of the genes for MOZ and TIF2.
Leukemia
Acute Monoblastic Leukemia with Erythrophagocytosis and Absence of KAT6A Rearrangement.
Leukemia
An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets.
Leukemia
BCR-ABL1 kinase facilitates localization of acetylated histones 3 and 4 on DNA double-strand breaks.
Leukemia
Berberine decreased N-acetylation of 2-aminofluorene through inhibition of N-acetyltransferase gene expression in human leukemia HL-60 cells.
Leukemia
Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis.
Leukemia
Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation.
Leukemia
BRD1-Mediated Acetylation Promotes Integrin ?V Gene Expression Via Interaction with Sulfatide.
Leukemia
Bromodomain and histone acetyltransferase domain specificities control mixed lineage leukemia phenotype.
Leukemia
Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.
Leukemia
Circadian locomotor output cycles kaput accelerates atherosclerotic plaque formation by upregulating plasminogen activator inhibitor-1 expression.
Leukemia
Clock gene modulation by TNF-alpha depends on calcium and p38 MAP kinase signaling.
Leukemia
Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription.
Leukemia
Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domain.
Leukemia
CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.
Leukemia
CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation.
Leukemia
Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.
Leukemia
Crystallization and preliminary X-ray diffraction analysis of the BRPF1 bromodomain in complex with its H2AK5ac and H4K12ac histone-peptide ligands.
Leukemia
Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.
Leukemia
Differential Expression of Circadian Genes in Leukemia and a Possible Role for Sirt1 in Restoring the Circadian Clock in Chronic Myeloid Leukemia.
Leukemia
Disease-related potential of mutations in transcriptional cofactors CREB-binding protein and p300 in leukemias.
Leukemia
Downregulating CREBBP inhibits proliferation and cell cycle progression and induces daunorubicin resistance in leukemia cells.
Leukemia
Effects of berberine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adduct formation in human leukemia cells.
Leukemia
Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play.
Leukemia
Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response.
Leukemia
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation.
Leukemia
Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.
Leukemia
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Leukemia
Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.
Leukemia
Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.
Leukemia
Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells.
Leukemia
Histone H3 Lysine 9 Acetylation Obstructs ATM Activation and Promotes Ionizing Radiation Sensitivity in Normal Stem Cells.
Leukemia
Histone methyltransferase EZH2 is transcriptionally induced by estradiol as well as estrogenic endocrine disruptors bisphenol-A and diethylstilbestrol.
Leukemia
Hypoxia Selects for a Quiescent, CML Stem/Leukemia Initiating- Like Population Dependent on CBP/Catenin Transcription.
Leukemia
Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein.
Leukemia
Inhibition of PCAF by Anacardic Acid Derivative Leads to Apoptosis and Breaks Resistance to DNA Damage in BCR-ABL-Expressing Cells.
Leukemia
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Leukemia
Leukemia inhibitory factor decreases the arylamine N-acetyltransferase activity in human cumulus granulosa cells.
Leukemia
Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Leukemia
Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course. A pilot study.
Leukemia
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
Leukemia
mof, a putative acetyl transferase gene related to the Tip60 and MOZ human genes and to the SAS genes of yeast, is required for dosage compensation in Drosophila.
Leukemia
Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.
Leukemia
Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells.
Leukemia
MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells.
Leukemia
MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease.
Leukemia
MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.
Leukemia
MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Leukemia
Mutations in multiple domains of c-Myb disrupt interaction with CBP/p300 and abrogate myeloid transforming ability.
Leukemia
MYST family histone acetyltransferases take center stage in stem cells and development.
Leukemia
N-ACETYLTRANSFERASE 2 POLYMORPHISMS AND SUSCEPTIBILITY TO INFANT LEUKEMIA WITH MATERNAL EXPOSURE TO DIPYRONE DURING PREGNANCY.
Leukemia
N-acetyltransferase is involved in baicalein-induced N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in human leukemia HL-60 cells.
Leukemia
New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias.
Leukemia
Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteins.
Leukemia
Overexpression of promyelocytic leukemia protein precludes the dispersal of ND10 structures and has no effect on accumulation of infectious herpes simplex virus 1 or its proteins.
Leukemia
Per2 Inhibits K562 Leukemia Cell Growth In Vitro and In Vivo Through Cell Cycle Arrest and Apoptosis Induction.
Leukemia
Probing the precision of the mitotic clock with a live-cell fluorescent biosensor.
Leukemia
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2.
Leukemia
Quinoline-based p300 histone acetyltransferase inhibitors with pro-apoptotic activity in human leukemia U937 cells.
Leukemia
Rearrangement of the MOZ gene in pediatric therapy-related myelodysplastic syndrome with a novel chromosomal translocation t(2;8)(p23;p11).
Leukemia
Reconstitution of active and stoichiometric multisubunit lysine acetyltransferase complexes in insect cells.
Leukemia
Regulation of germinal center responses and B-cell memory by the chromatin modifier MOZ.
Leukemia
Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.
Leukemia
Retroviral transduction model of mixed lineage leukemia fused to CREB binding protein.
Leukemia
Revisiting allostery in CREB-binding protein (CBP) using residue-based interaction energy.
Leukemia
Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis.
Leukemia
Sea-Blue Histiocytosis of Bone Marrow in a Patient with t(8;22) Acute Myeloid Leukemia.
Leukemia
Secondary acute monocytic leukemia with a translocation t(8;16)(p11;p13): case report and review of the literature.
Leukemia
Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter.
Leukemia
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
Leukemia
Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Leukemia
t(8;16)(p11;p13) predisposes to a transient but potentially recurring neonatal leukemia.
Leukemia
Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.
Leukemia
The DAC system and associations with acute leukemias and myelodysplastic syndromes.
Leukemia
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases.
Leukemia
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors.
Leukemia
The histone acetyltransferase TIP60 interacts with c-Myb and inactivates its transcriptional activity in human leukemia.
Leukemia
The human monocytic leukemia zinc finger histone acetyltransferase domain contains DNA-binding activity implicated in chromatin targeting.
Leukemia
The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).
Leukemia
The mixed lineage leukemia 4 (MLL4) methyltransferase complex is involved in transforming growth factor beta (TGF-?)-activated gene transcription.
Leukemia
The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body.
Leukemia
Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
Leukemia
Transcriptional repression and cell death induced by nuclear aggregates of non-polyglutamine protein.
Leukemia
Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.
Leukemia
Up-regulation of PER3 Expression Is Correlated with Better Clinical Outcome in Acute Leukemia.
Leukemia
Viral and cellular factors that target the promyelocytic leukemia oncogenic domains strongly activate a glucocorticoid-responsive promoter.
Leukemia
Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells.
Leukemia
[Expression and Mechanism of KAT2A and CDK4/CDK6 in Children with Acute Leukemia].
Leukemia
[Reverse correlation between natural resistance of mice to transplanted leukemia EL-4 and rectal temperature]
Leukemia, Erythroblastic, Acute
CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation.
Leukemia, Lymphocytic, Chronic, B-Cell
Deregulated expression of circadian clock and clock-controlled cell cycle genes in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.
Leukemia, Lymphocytic, Chronic, B-Cell
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Leukemia, Monocytic, Acute
Acute Monoblastic Leukemia with Erythrophagocytosis and Absence of KAT6A Rearrangement.
Leukemia, Monocytic, Acute
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation.
Leukemia, Monocytic, Acute
MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).
Leukemia, Monocytic, Acute
New types of MYST3-CBP and CBP-MYST3 fusion transcripts in t(8;16)(p11;p13) acute myeloid leukemias.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Altered expression of circadian clock genes in human chronic myeloid leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Circadian clock gene Period2 suppresses human chronic myeloid leukemia cell proliferation.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Differential Expression of Circadian Genes in Leukemia and a Possible Role for Sirt1 in Restoring the Circadian Clock in Chronic Myeloid Leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia.
Leukemia, Myeloid
Acetylation of lysine564 adjacent to the CTBP-binding motif in EVI1 is crucial for transcriptional activation of GATA2.
Leukemia, Myeloid
Differential Expression of Circadian Genes in Leukemia and a Possible Role for Sirt1 in Restoring the Circadian Clock in Chronic Myeloid Leukemia.
Leukemia, Myeloid
Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
Leukemia, Myeloid
Genetic variability in N-acetyltransferase 2 gene determines susceptibility to childhood lymphoid or myeloid leukemia in Brazil.
Leukemia, Myeloid
Retroviral transduction model of mixed lineage leukemia fused to CREB binding protein.
Leukemia, Myeloid
The histone acetyl transferase activity of monocytic leukemia zinc finger is critical for the proliferation of hematopoietic precursors.
Leukemia, Myeloid
[Identification of acute leukemia-specific genes from leukemia recipient/sibling donor pairs by distinguishing study with oligonucleotide microarrays]
Leukemia, Myeloid, Acute
A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb.
Leukemia, Myeloid, Acute
Acute myeloid leukemia with erythrophagocytosis indicative of KAT6A rearrangement.
Leukemia, Myeloid, Acute
Bromodomain and histone acetyltransferase domain specificities control mixed lineage leukemia phenotype.
Leukemia, Myeloid, Acute
Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.
Leukemia, Myeloid, Acute
Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development.
Leukemia, Myeloid, Acute
Chromosome 8p11.2 translocations: prevalence, FISH analysis for FGFR1 and MYST3, and clinicopathologic correlates in a consecutive cohort of 13 cases from a single institution.
Leukemia, Myeloid, Acute
CITED2 affects leukemic cell survival by interfering with p53 activation.
Leukemia, Myeloid, Acute
Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments.
Leukemia, Myeloid, Acute
Differential Expression of Circadian Genes in Leukemia and a Possible Role for Sirt1 in Restoring the Circadian Clock in Chronic Myeloid Leukemia.
Leukemia, Myeloid, Acute
Expression of the MOZ-TIF2 oncoprotein in mice represses senescence.
Leukemia, Myeloid, Acute
KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
Leukemia, Myeloid, Acute
Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukemia stem-like cells.
Leukemia, Myeloid, Acute
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
Leukemia, Myeloid, Acute
Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells.
Leukemia, Myeloid, Acute
MOZ and MOZ-CBP cooperate with NF-kappaB to activate transcription from NF-kappaB-dependent promoters.
Leukemia, Myeloid, Acute
MOZ increases p53 acetylation and premature senescence through its complex formation with PML.
Leukemia, Myeloid, Acute
MOZ regulates B cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.
Leukemia, Myeloid, Acute
NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma.
Leukemia, Myeloid, Acute
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2.
Leukemia, Myeloid, Acute
Retroviral transduction model of mixed lineage leukemia fused to CREB binding protein.
Leukemia, Myeloid, Acute
t(10;16)(q22;p13) and MORF-CREBBP fusion is a recurrent event in acute myeloid leukemia.
Leukemia, Myeloid, Acute
t(8;16)(p11;p13) predisposes to a transient but potentially recurring neonatal leukemia.
Leukemia, Myeloid, Acute
The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice.
Leukemia, Myeloid, Acute
The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13).
Leukemia, Myeloid, Acute
The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase.
Leukemia, Myeloid, Acute
The MOZ Histone Acetyltransferase in Epigenetic Signaling and Disease.
Leukemia, Myeloid, Acute
Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
Leukemia, Myeloid, Acute
Uterine leiomyomata with t(10;17) disrupt the histone acetyltransferase MORF.
Leukemia, Myeloid, Acute
Whole exome sequencing reveals de novo pathogenic variants in KAT6A as a cause of a neurodevelopmental disorder.
Leukemia, Myelomonocytic, Juvenile
CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia.
Leukemia, T-Cell
Activation of HTLV-I gene transcription by protein tyrosine phosphatase inhibitors.
Leukemia, T-Cell
Activator-dependent p300 acetylation of chromatin in vitro: enhancement of transcription by disruption of repressive nucleosome-nucleosome interactions.
Leukemia, T-Cell
Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation.
Leukemia, T-Cell
Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis.
Leukemia, T-Cell
c-Maf suppresses human T-cell leukemia virus type 1 Tax by competing for CREB-binding protein.
Leukemia, T-Cell
Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.
Leukemia, T-Cell
Human T-cell leukemia virus type 1 Tax modulates interferon-alpha signal transduction through competitive usage of the coactivator CBP/p300.
Leukemia, T-Cell
Human T-cell leukemia virus type 1 Tax requires direct access to DNA for recruitment of CREB binding protein to the viral promoter.
Leukemia, T-Cell
p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300.
Leukemia, T-Cell
The human T-cell leukemia virus type 1 oncoprotein Tax inhibits the transcriptional activity of c-Myb through competition for the CREB binding protein.
Leukemia, T-Cell
The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.
Leukemia, T-Cell
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
Leukemia-Lymphoma, Adult T-Cell
Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma.
Leukemia-Lymphoma, Adult T-Cell
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies.
Leukocytosis
Chronic Exposure to Continuous Brightness or Darkness Modulates Immune Responses and Ameliorates the Antioxidant Enzyme System in Male Rats.
Leukoplakia, Oral
Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer.
Lewy Body Disease
Metabolic alterations associated with impaired clock drawing in Lewy body dementia.
Lewy Body Disease
Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases.
Lipid Metabolism Disorders
Does a high-fat diet affect the circadian clock, or is it the other way around? A systematic review.
Lipid Metabolism Disorders
Effects of altered photoperiod on circadian clock and lipid metabolism in rats.
Lipid Metabolism Disorders
Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans.
Lipodystrophy
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice.
Lipoma
Assessment of the clinical and molecular impact of different cytogenetic subgroups in a series of 272 lipomas with abnormal karyotype.
Liposarcoma
Arginine methylation of translocated in liposarcoma (TLS) inhibits its binding to long noncoding RNA, abrogating TLS-mediated repression of CBP/p300 activity.
Liposarcoma
Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis.
Liver Cirrhosis
Loss of clock gene mPer2 promotes liver fibrosis induced by carbon tetrachloride.
Liver Cirrhosis
p300/CBP as a Key Nutritional Sensor for Hepatic Energy Homeostasis and Liver Fibrosis.
Liver Cirrhosis
Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
Liver Cirrhosis
Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis.
Liver Cirrhosis
[Changes in the 24-hour rhythm of plasma melatonin in patients with liver cirrhosis--relation to sleep architecture]
Liver Cirrhosis, Alcoholic
Polymorphism of N-acetyltransferase 2 Gene and the Susceptibility to Alcoholic Liver Cirrhosis: Interaction With Smoking.
Liver Cirrhosis, Biliary
Are primary biliary cirrhosis and autoimmune cholangitis reflective of the pendulum of a clock and therefore represent a 'phase' of the same disease?
Liver Diseases
3,4-dihydroxytoluene, a metabolite of rutin, suppresses the progression of nonalcoholic fatty liver disease in mice by inhibiting p300 histone acetyltransferase activity.
Liver Diseases
Alcohol and Liver Clock Disruption Increase Small Droplet Macrosteatosis, Alter Lipid Metabolism and Clock Gene mRNA Rhythms, and Remodel the Triglyceride Lipidome in Mouse Liver.
Liver Diseases
Black Mulberry Extract Elicits Hepatoprotective Effects in Nonalcoholic Fatty Liver Disease Models by Inhibition of Histone Acetylation.
Liver Diseases
Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease.
Liver Diseases
Circadian gene Clock participates in mitochondrial apoptosis pathways by regulating mitochondrial membrane potential, mitochondria out membrane permeablization and apoptosis factors in AML12 hepatocytes.
Liver Diseases
Circadian rhythms of liver physiology and disease: experimental and clinical evidence.
Liver Diseases
Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease.
Liver Diseases
Disturbances in the murine hepatic circadian clock in alcohol-induced hepatic steatosis.
Liver Diseases
Diurnal rhythm of follicle-stimulating hormone is associated with nonalcoholic fatty liver disease in a Chinese elderly population.
Liver Diseases
Emerging role of circadian clock disruption in alcohol-induced liver disease.
Liver Diseases
First-in-human phase I study of JPH203, an L-type amino acid transporter 1 inhibitor, in patients with advanced solid tumors.
Liver Diseases
Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies.
Liver Diseases
Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease.
Liver Diseases
Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.
Liver Diseases
Polymorphism of N-acetyltransferase 2 Gene and the Susceptibility to Alcoholic Liver Cirrhosis: Interaction With Smoking.
Liver Diseases
Prediction of chronic liver diseases on the basis of the N-acetyltransferase 2 phenotype.
Liver Diseases
Relationship between antipyrine metabolism and acetylation phenotype in health and chronic liver diseases.
Liver Diseases
Relationship between clock and star drawing and the degree of hepatic encephalopathy.
Liver Diseases
Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.
Liver Diseases
Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model.
Liver Diseases
The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis.
Liver Diseases
The hepatic BMAL1/AKT/Lipogenesis axis protects against alcoholic liver disease via promoting PPAR? pathway.
Liver Diseases
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Liver Diseases
The role of astrocytes in generating circadian rhythmicity in health and disease.
Liver Diseases
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.
Liver Diseases, Alcoholic
N-acetyltransferase 2 polymorphism is not related to the risk of advanced alcoholic liver disease.
Liver Diseases, Alcoholic
Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock.
Liver Failure, Acute
Pyruvate dehydrogenase complex and lactate dehydrogenase as targets for therapy of acute liver failure.
Liver Neoplasms
Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer.
Liver Neoplasms
Are polymorphisms of N-acetyltransferase genes susceptible to primary liver cancer in Luoyang, China?
Liver Neoplasms
Circadian clock gene expression regulates cancer cell growth through glutaminase.
Liver Neoplasms
Circadian rhythms of liver physiology and disease: experimental and clinical evidence.
Liver Neoplasms
Effect of Daytime Blue-enriched LED Light on the Nighttime Circadian Melatonin Inhibition of Hepatoma 7288CTC Warburg Effect and Progression.
Liver Neoplasms
miR-639 Expression Is Silenced by DNMT3A-Mediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer Cells.
Liver Neoplasms
Olaparib enhances curcumin-mediated apoptosis in oral cancer cells by inducing PARP trapping through modulation of BER and chromatin assembly.
Loeys-Dietz Syndrome
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Lung Diseases
A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.
Lung Diseases
Bringing the cellular clock into understanding lung disease: it's time, period!
Lung Injury
Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.
Lung Injury
Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation.
Lung Injury
ZFP36 protects lungs from intestinal I/R-induced injury and fibrosis through the CREBBP/p53/p21/Bax pathway.
Lung Neoplasms
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
Lung Neoplasms
A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL.
Lung Neoplasms
A pilot study testing the genetic polymorphism of N-acetyltransferase 2 as a risk factor in lung cancer.
Lung Neoplasms
Association between CLOCK, PER3 and CCRN4L with non?small cell lung cancer in Brazilian patients.
Lung Neoplasms
Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis.
Lung Neoplasms
BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300.
Lung Neoplasms
C646, a selective small molecule inhibitor of histone acetyltransferase p300, radiosensitizes lung cancer cells by enhancing mitotic catastrophe.
Lung Neoplasms
Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats.
Lung Neoplasms
Circadian clock gene Per2 downregulation in non?small cell lung cancer is associated with tumour progression and metastasis.
Lung Neoplasms
Circadian clock gene Period2 suppresses human chronic myeloid leukemia cell proliferation.
Lung Neoplasms
Clock time and embodied time experienced by patients with inoperable lung cancer.
Lung Neoplasms
CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway.
Lung Neoplasms
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition.
Lung Neoplasms
Curcumin inhibited the arylamines N-acetyltransferase activity, gene expression and DNA adduct formation in human lung cancer cells (A549).
Lung Neoplasms
Cytotoxic and N-Acetyltransferase Inhibitory Meroterpenoids from Ganoderma cochlear.
Lung Neoplasms
Cytotoxic Effects of 24-Methylenecyloartanyl Ferulate on A549 Nonsmall Cell Lung Cancer Cells through MYBBP1A Up-Regulation and AKT and Aurora B Kinase Inhibition.
Lung Neoplasms
DDIT3 and KAT2A regulate TNFRSF10A and TNFRSF10B expression in endoplasmic reticulum stress-mediated apoptosis in human lung cancer cells.
Lung Neoplasms
Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk.
Lung Neoplasms
Effect of berberine on activity and mRNA expression of N-acetyltransferase in human lung cancer cell line A549.
Lung Neoplasms
Epigallocatechin?3?gallate inhibits self?renewal ability of lung cancer stem?like cells through inhibition of CLOCK.
Lung Neoplasms
Genetic polymorphisms in CYP1B1, GSTA1, NQO1 and NAT2 and the risk of lung cancer.
Lung Neoplasms
Genetic polymorphisms of phase II metabolic enzymes and lung cancer susceptibility in a population of Central South China.
Lung Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Lung Neoplasms
Glutathione S-transferase mu1 and N-acetyltransferase 2 genetic polymorphisms and exposure to tobacco smoke in nonsmoking and smoking lung cancer patients and population controls.
Lung Neoplasms
Histone acetyltransferase hMOF promotes S phase entry and tumorigenesis in lung cancer.
Lung Neoplasms
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.
Lung Neoplasms
hnRNPA2/B1 activates cyclooxygenase-2 and promotes tumor growth in human lung cancers.
Lung Neoplasms
Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation.
Lung Neoplasms
Identification of the SOX2 interactome by BioID reveals EP300 as a mediator of SOX2-dependent squamous differentiation and lung squamous cell carcinoma growth.
Lung Neoplasms
Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity.
Lung Neoplasms
KAT2B is an immune infiltration-associated biomarker predicting prognosis and response to immunotherapy in non-small cell lung cancer.
Lung Neoplasms
KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.
Lung Neoplasms
N-acetylation polymorphism in patients with lung cancer and its association with p53 gene mutation.
Lung Neoplasms
N-Acetyltransferase 2 (NAT2) gene polymorphism and exposure to smoking in lung cancer of Chinese males.
Lung Neoplasms
N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients.
Lung Neoplasms
NAT2 and CYP1A2 polymorphisms and lung cancer risk in relation to smoking status.
Lung Neoplasms
Notch1/TAZ axis promotes aerobic glycolysis and immune escape in lung cancer.
Lung Neoplasms
Novel genetic variants in HDAC2 and PPARGC1A of the CREB-binding protein pathway predict survival of non-small-cell lung cancer.
Lung Neoplasms
Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells.
Lung Neoplasms
Paclitaxel (taxol) inhibits the arylamine N-acetyltransferase activity and gene expression (mRNA NAT1) and 2-aminofluorene-DNA adduct formation in human bladder carcinoma cells (T24 and TSGH 8301).
Lung Neoplasms
Period 3, a tumor suppressor in non-small cell lung cancer, is silenced by hypermethylation.
Lung Neoplasms
Polymorphism of selected enzymes involved in detoxification and biotransformation in relation to lung cancer.
Lung Neoplasms
Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.
Lung Neoplasms
Sequence variants of NAT1 and NAT2 and other xenometabolic genes and risk of lung and aerodigestive tract cancers in Central Europe.
Lung Neoplasms
SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString).
Lung Neoplasms
Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines.
Lung Neoplasms
Tat-interactive Protein-60KDA (TIP60) Regulates the Tumorigenesis of Lung Cancer In Vitro.
Lung Neoplasms
The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase.
Lung Neoplasms
Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance.
Lung Neoplasms
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Lung Neoplasms
Tip60-siRNA regulates ABCE1 acetylation to suppress lung cancer growth via activation of the apoptotic signaling pathway.
Lung Neoplasms
Whole-exome sequencing to identify novel somatic mutations in squamous cell lung cancers.
Lung Neoplasms
[hARD1 antiserum preparation and primary immunohistochemical analysis of hARD1 in tumor tissues]
Lung Neoplasms
[Lung cancer and its epigenetics association with chronic obstructive pulmonary disease].
Lung Neoplasms
[Polymorphism in the N-acetyltransferase 2 gene in patients with lung cancer. Short communication].
Lung Neoplasms
[Role of gene polymorphisms of phase II of xenobiotic biotransformation from glutathione-S-transferase and N-acetyltransferase families in susceptibility to lung cancer among Mayak workers].
Lupus Erythematosus, Systemic
Association of PER2 gene single nucleotide polymorphisms with genetic susceptibility to systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus.
Lupus Erythematosus, Systemic
Cigarette smoking, N-acetyltransferase 2 polymorphisms and systemic lupus erythematosus in a Japanese population.
Lupus Erythematosus, Systemic
Reversal of autoimmune disease in lupus-prone New Zealand black/New Zealand white mice by nonmyeloablative transplantation of purified allogeneic hematopoietic stem cells.
Lymphatic Metastasis
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Lymphatic Metastasis
Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
Lymphatic Metastasis
Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases.
Lymphoma
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
Lymphoma
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
Lymphoma
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.
Lymphoma
Case Report: Multiple Chromosomal Translocations Including Novel CIITA-CREBBP Fusion and Mutations in a Follicular Lymphoma.
Lymphoma
CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells.
Lymphoma
Clinical efficacy and molecular biomarkers in a phase II study of tucidinostat plus R-CHOP in elderly patients with newly diagnosed diffuse large B-cell lymphoma.
Lymphoma
Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence.
Lymphoma
Correction: The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP.
Lymphoma
CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation.
Lymphoma
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
Lymphoma
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP.
Lymphoma
GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways.
Lymphoma
Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
Lymphoma
Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi's Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells.
Lymphoma
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Lymphoma
Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.
Lymphoma
Mutational landscape of T-cell lymphoma in mice lacking the DNA mismatch repair gene Mlh1: no synergism with ionizing radiation.
Lymphoma
Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.
Lymphoma
Precision Targeting with EZH2 and HDAC Inhibitors in Epigenetically Dysregulated Lymphomas.
Lymphoma
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
Lymphoma
The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations in TNFAIP3 followed by mutations in TBL1XR1 and CREBBP.
Lymphoma
The reciprocal interplay between TNF? and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells.
Lymphoma
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
Lymphoma
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Lymphoma
Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma.
Lymphoma
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Lymphoma, B-Cell
A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity.
Lymphoma, B-Cell
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
Lymphoma, B-Cell
Bone Metastasis in Advanced Breast Cancer: Analysis of Gene Expression Microarray.
Lymphoma, B-Cell
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.
Lymphoma, B-Cell
Case Report: Multiple Chromosomal Translocations Including Novel CIITA-CREBBP Fusion and Mutations in a Follicular Lymphoma.
Lymphoma, B-Cell
CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma.
Lymphoma, B-Cell
CREBBP cooperates with the cell cycle machinery to attenuate chidamide sensitivity in relapsed/refractory diffuse large B-cell lymphoma.
Lymphoma, B-Cell
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Lymphoma, B-Cell
Crebbp loss cooperates with Bcl2 over-expression to promote lymphoma in mice.
Lymphoma, B-Cell
Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.
Lymphoma, B-Cell
Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes.
Lymphoma, B-Cell
Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
Lymphoma, B-Cell
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP.
Lymphoma, B-Cell
Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
Lymphoma, B-Cell
Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Genetic polymorphism and transcriptional regulation of CREBBP gene in patient with diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.
Lymphoma, B-Cell
Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.
Lymphoma, B-Cell
Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
Lymphoma, B-Cell
JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte rich large B-cell lymphoma.
Lymphoma, B-Cell
Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.
Lymphoma, B-Cell
Reverse translational strategies for developing animal models of bipolar disorder.
Lymphoma, B-Cell
Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma.
Lymphoma, B-Cell
Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones.
Lymphoma, B-Cell
Stress-induced cell-cycle activation in tip60 haploinsufficient adult cardiomyocytes.
Lymphoma, B-Cell
Targeted next generation sequencing reveals high mutation frequency of CREBBP, BCL2 and KMT2D in high-grade B-cell lymphoma with MYC and BCL2 and /or BCL6 rearrangements.
Lymphoma, B-Cell
TBLR1 and CREBBP as potential novel prognostic immunohistochemical biomarkers in diffuse large B-cell lymphoma.
Lymphoma, B-Cell
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
Lymphoma, B-Cell
The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma.
Lymphoma, B-Cell
Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma.
Lymphoma, B-Cell
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Lymphoma, Follicular
Case Report: Multiple Chromosomal Translocations Including Novel CIITA-CREBBP Fusion and Mutations in a Follicular Lymphoma.
Lymphoma, Follicular
CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.
Lymphoma, Follicular
CREBBP and STAT6 co-mutation and 16p13 and 1p36 loss define the t(14;18)-negative diffuse variant of follicular lymphoma.
Lymphoma, Follicular
Crebbp loss cooperates with Bcl2 over-expression to promote lymphoma in mice.
Lymphoma, Follicular
Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes.
Lymphoma, Follicular
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.
Lymphoma, Follicular
Molecular ontogeny of donor-derived follicular lymphomas occurring after hematopoietic cell transplantation.
Lymphoma, Follicular
Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma.
Lymphoma, Follicular
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
Lymphoma, Follicular
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Lymphoma, Large B-Cell, Diffuse
A rearranged EP300 gene in the human B-cell lymphoma cell line RC-K8 encodes a disabled transcriptional co-activator that contributes to cell growth and oncogenicity.
Lymphoma, Large B-Cell, Diffuse
BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy.
Lymphoma, Large B-Cell, Diffuse
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.
Lymphoma, Large B-Cell, Diffuse
CREBBP cooperates with the cell cycle machinery to attenuate chidamide sensitivity in relapsed/refractory diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Crebbp loss cooperates with Bcl2 over-expression to promote lymphoma in mice.
Lymphoma, Large B-Cell, Diffuse
Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.
Lymphoma, Large B-Cell, Diffuse
Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes.
Lymphoma, Large B-Cell, Diffuse
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP.
Lymphoma, Large B-Cell, Diffuse
Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
Lymphoma, Large B-Cell, Diffuse
Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Genetic polymorphism and transcriptional regulation of CREBBP gene in patient with diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.
Lymphoma, Large B-Cell, Diffuse
Histone acetyltransferase-deficient p300 mutants in diffuse large B cell lymphoma have altered transcriptional regulatory activities and are required for optimal cell growth.
Lymphoma, Large B-Cell, Diffuse
Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
Lymphoma, Large B-Cell, Diffuse
Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.
Lymphoma, Large B-Cell, Diffuse
Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones.
Lymphoma, Large B-Cell, Diffuse
TBLR1 and CREBBP as potential novel prognostic immunohistochemical biomarkers in diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
Lymphoma, Large B-Cell, Diffuse
Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma.
Lymphoma, Non-Hodgkin
Ala394Thr polymorphism in the clock gene NPAS2: a circadian modifier for the risk of non-Hodgkin's lymphoma.
Lymphoma, Non-Hodgkin
Association of NAT and GST polymorphisms with non-Hodgkin's lymphoma: a population-based case-control study.
Lymphoma, Non-Hodgkin
Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Lymphoma, Non-Hodgkin
Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Re: Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma, author response.
Lymphoma, Non-Hodgkin
Smoking, variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma: a pooled analysis within the InterLymph consortium.
Lymphoma, Non-Hodgkin
[N-acetyltransferase activity during growth of the transplantable Pliss lymphosarcoma and during pregnancy in rats]
Lysosomal Storage Diseases
Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.
Lysosomal Storage Diseases
The Biological Clock and the Molecular Basis of Lysosomal Storage Diseases.
Lysosomal Storage Diseases
Update of the spectrum of mucopolysaccharidoses type III in Tunisia: identification of three novel mutations and in silico structural analysis of the missense mutations.
Magnesium Deficiency
Early transcriptomic changes induced by magnesium deficiency in Arabidopsis thaliana reveal the alteration of circadian clock gene expression in roots and the triggering of abscisic acid-responsive genes.
Malaria
A unique GCN5 histone acetyltransferase complex controls erythrocyte invasion and virulence in the malaria parasite Plasmodium falciparum.
Malaria
Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species.
Malaria
Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase 2 genes on the metabolism of artemisinin-based combination therapies in malaria patients from Cambodia and Tanzania.
Malaria
Extensive circadian and light regulation of the transcriptome in the malaria mosquito Anopheles gambiae.
Malaria
Investigating associations between biting time in the malaria vector Anopheles arabiensis Patton and single nucleotide polymorphisms in circadian clock genes: support for sub-structure among An. arabiensis in the Kilombero valley of Tanzania.
Malaria
The MYST Family Histone Acetyltransferase Regulates Gene Expression and Cell Cycle in Malaria Parasite Plasmodium falciparum.
Malnutrition
Circadian rhythms of locomotor activity and hippocampal clock genes expression are dampened in vitamin A-deficient rats.
Malnutrition
Long-Lasting Effect of Perinatal Exposure to L-tryptophan on Circadian Clock of Primary Cell Lines Established from Male Offspring Born from Mothers Fed on Dietary Protein Restriction.
Malnutrition
Nutritional screening of patients at a memory clinic - association between patients' and their relatives' self-reports.
Malnutrition
Perinatal nutrient restriction induces long-lasting alterations in the circadian expression pattern of genes regulating food intake and energy metabolism.
Malnutrition
Protein malnutrition after weaning disrupts peripheral clock and daily insulin secretion in mice.
Malnutrition
The type 2 diabetes-specific dementia risk score (DSDRS) is associated with frailty, cognitive and functional status amongst Mexican community-dwelling older adults.
Malocclusion
Epigenetic influence of KAT6B and HDAC4 in the development of skeletal malocclusion.
Malocclusion
Molecular motor MYO1C, acetyltransferase KAT6B and osteogenetic transcription factor RUNX2 expression in human masseter muscle contributes to development of malocclusion.
Mania
An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors.
Mania
An inhibitor of casein kinase 1 ?/? partially normalizes the manic-like behaviors of the Clock?19 mouse.
Mania
Circadian Disruptions in the Myshkin Mouse Model of Mania Are Independent of Deficits in Suprachiasmatic Molecular Clock Function.
Mania
Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder.
Mania
Further evidence for Clock?19 mice as a model for bipolar disorder mania using cross-species tests of exploration and sensorimotor gating.
Mania
Knockdown of Clock in the ventral tegmental area through RNA interference results in a mixed state of mania and depression-like behavior.
Mania
Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours.
Mania
Specific Role of VTA Dopamine Neuronal Firing Rates and Morphology in the Reversal of Anxiety-Related, but not Depression-Related Behavior in the Clock?19 Mouse Model of Mania.
Mania
The Mood Stabilizer Valproic Acid Opposes the Effects of Dopamine on Circadian Rhythms.
Massive Hepatic Necrosis
Circadian Control of Inflammasome Pathways: Implications for Circadian Medicine.
Measles
Global spatiotemporal transmission dynamics of measles virus clade D genotypes in the context of the measles elimination goal 2020 in India.
Medulloblastoma
Identification of Hub Genes in Pediatric Medulloblastoma by Multiple-Microarray Analysis.
Medulloblastoma
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
Medulloblastoma
Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation.
Medulloblastoma
The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma.
Melanoma
Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors.
Melanoma
Analysis of Genetic Alterations in Cutaneous Malignant Melanomas Unveils Unique Loco-Regional Variations and Novel Predictors of Metastatic Potential.
Melanoma
Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma.
Melanoma
Circadian clock protein BMAL1 regulates melanogenesis through MITF in melanoma cells.
Melanoma
Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2).
Melanoma
Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma.
Melanoma
Gender-specific associations between polymorphisms of the circadian gene RORA and cutaneous melanoma susceptibility.
Melanoma
Humoral immune response against melanoma antigens induced by vaccination with cytokine gene-modified autologous tumor cells.
Melanoma
Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes: The ABCDEF Guide.
Melanoma
L-Theanine inhibits melanoma cell growth and migration via regulating expression of the clock gene BMAL1.
Melanoma
Loss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1R.
Melanoma
Management of conjunctival and corneal melanoma with surgical excision, amniotic membrane allograft, and topical chemotherapy.
Melanoma
Melanopsin, a Canonical Light Receptor, Mediates Thermal Activation of Clock Genes.
Melanoma
MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma.
Melanoma
Non-Metastatic Cutaneous Melanoma Induces Chronodisruption in Central and Peripheral Circadian Clocks.
Melanoma
Polyphenols from green tea inhibit the growth of melanoma cells through inhibition of class I histone deacetylases and induction of DNA damage.
Melanoma
Primary acquired melanosis of the conjunctiva: risks for progression to melanoma in 311 eyes. The 2006 Lorenz E. Zimmerman lecture.
Melanoma
Ras-ERK1/2 signaling promotes the development of uveal melanoma by downregulating H3K14ac.
Melanoma
Selective Inhibition of p300 HAT Blocks Cell Cycle Progression, Induces Cellular Senescence, and Inhibits the DNA Damage Response in Melanoma Cells.
Melanoma
Targeting lineage-specific MITF pathway in human melanoma cell lines by A-485, the selective small molecule inhibitor of p300/CBP.
Melanoma
The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models.
Melanoma
The molecular clock in the skin, its functionality, and how it is disrupted in cutaneous melanoma: a new pharmacological target?
Melanoma
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
Melanoma
VCAM-1-, ELAM-1-, and ICAM-1-independent adhesion of melanoma cells to cultured human dermal microvascular endothelial cells.
Melanoma, Experimental
Enhancing circadian clock function in cancer cells inhibits tumor growth.
Melanosis
Primary acquired melanosis of the conjunctiva: risks for progression to melanoma in 311 eyes. The 2006 Lorenz E. Zimmerman lecture.
Memory Disorders
CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease.
Memory Disorders
CREB binding protein is required for both short-term and long-term memory formation.
Memory Disorders
Effects of internal clock and memory disorders on duration reproductions and duration productions in patients with Parkinson's disease.
Memory Disorders
Epigenetic control of learning and memory in Drosophila by Tip60 HAT action.
Memory Disorders
Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.
Memory Disorders
The Clock Drawing Test for dementia of the Alzheimer's type: A comparison of three scoring methods in a memory disorders clinic.
Memory Disorders
Time perception depends on accurate clock mechanisms as well as unimpaired attention and memory processes.
Memory Disorders
Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60.
Meningioma
The CREB-binding protein inhibitor ICG-001: a promising therapeutic strategy in sporadic meningioma with NF2 mutations.
Meningitis, Bacterial
Therapy of community-acquired acute bacterial meningitis: the clock is running.
Meningoencephalitis
Rubinstein-Taybi syndrome and CREBBP c.201 202delTA mutation: a case presenting with varicella meningoencephalitis.
Mental Retardation, X-Linked
A Neuronal Activity-Dependent Dual Function Chromatin-Modifying Complex Regulates Arc Expression(1,2,3).
Mesothelioma
The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma.
Mesothelioma, Malignant
The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma.
Metabolic Diseases
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.
Metabolic Diseases
A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude.
Metabolic Diseases
A Mathematical Model of the Liver Circadian Clock Linking Feeding and Fasting Cycles to Clock Function.
Metabolic Diseases
A time to fast, a time to feast: the crosstalk between metabolism and the circadian clock.
Metabolic Diseases
Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts.
Metabolic Diseases
AMP-activated protein kinase as a key molecular link between metabolism and clockwork.
Metabolic Diseases
Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock.
Metabolic Diseases
Beneficial Effects of Early Time-Restricted Feeding on Metabolic Diseases: Importance of Aligning Food Habits with the Circadian Clock.
Metabolic Diseases
Chronic treatment with dexamethasone alters clock gene expression and melatonin synthesis in rat pineal gland at night.
Metabolic Diseases
Circadian metabolic regulation through crosstalk between casein kinase 1? and transcriptional coactivator PGC-1?.
Metabolic Diseases
Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks.
Metabolic Diseases
Circadian rhythms and exercise - re-setting the clock in metabolic disease.
Metabolic Diseases
Clock gene expression in peripheral leucocytes of patients with type 2 diabetes.
Metabolic Diseases
Cognitive impairment with diabetes mellitus and metabolic disease: innovative insights with the mechanistic target of rapamycin and circadian clock gene pathways.
Metabolic Diseases
Deficiency of intestinal Bmal1 prevents obesity induced by high-fat feeding.
Metabolic Diseases
Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes.
Metabolic Diseases
Glycemic control is impaired in the evening in prediabetes through multiple diurnal rhythms.
Metabolic Diseases
Health benefits of dietary chronobiotics: beyond resynchronizing internal clocks.
Metabolic Diseases
Hormones and the autonomic nervous system are involved in suprachiasmatic nucleus modulation of glucose homeostasis.
Metabolic Diseases
Host-Microbiota Interaction and Intestinal Epithelial Functions under Circadian Control: Implications in Colitis and Metabolic Disorders.
Metabolic Diseases
Mathematical modeling informs the impact of changes in circadian rhythms and meal patterns on insulin secretion.
Metabolic Diseases
Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism.
Metabolic Diseases
New Horizons: Circadian control of metabolism offers novel insight into the cause and treatment of metabolic diseases.
Metabolic Diseases
Nobiletin protects against insulin resistance and disorders of lipid metabolism by reprogramming of circadian clock in hepatocytes.
Metabolic Diseases
Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology.
Metabolic Diseases
Preventive effect of L-carnitine on the disorder of lipid metabolism and circadian cClock of mice subjected to chronic jet-lag.
Metabolic Diseases
Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis.
Metabolic Diseases
The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erb? and indirectly via Cebpb/(C/ebp?) in zebrafish.
Metabolic Diseases
The circadian timing system: a recent addition in the physiological mechanisms underlying pathological and aging processes.
Metabolic Diseases
The cost of circadian desynchrony: Evidence, insights and open questions.
Metabolic Diseases
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Metabolic Diseases
Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.
Metabolic Diseases
Time-restricted feeding regulates molecular mechanisms with involvement of circadian rhythm to prevent metabolic diseases.
Metabolic Diseases
Visceral adiposity and expression of clock genes in peripheral blood mononuclear cells: A pilot study.
Metabolic Diseases
Western diet-induced obesity disrupts the diurnal rhythmicity of hippocampal core clock gene expression in a mouse model.
Metabolic Diseases
White Adipose Tissue and Circadian Rhythm Dysfunctions in Obesity: Pathogenesis and Available Therapies.
Metabolic Diseases
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.
Metabolic Diseases
[Sleep/wake cycle, circadian disruption and the development of obesity].
Metabolic Syndrome
"Diabetes of the elderly" and type 2 diabetes in younger patients: possible role of the biological clock.
Metabolic Syndrome
A Period 2 genetic variant interacts with plasma SFA to modify plasma lipid concentrations in adults with metabolic syndrome.
Metabolic Syndrome
Altered clock gene expression in obese visceral adipose tissue is associated with metabolic syndrome.
Metabolic Syndrome
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
Metabolic Syndrome
Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome.
Metabolic Syndrome
Cardiac Autonomic Neuropathy in Diabetes: A Predictor of Cardiometabolic Events.
Metabolic Syndrome
Chrono-Drug Discovery and Development Based on Circadian Rhythm of Molecular, Cellular and Organ Level.
Metabolic Syndrome
Chrono-immunology: progress and challenges in understanding links between the circadian and immune systems.
Metabolic Syndrome
Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction.
Metabolic Syndrome
Chronopharmacological strategies: Intra- and inter-individual variability of molecular clock.
Metabolic Syndrome
Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.
Metabolic Syndrome
Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver.
Metabolic Syndrome
Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters.
Metabolic Syndrome
Circadian rhythms of glucocorticoid hormone actions in target tissues: potential clinical implications.
Metabolic Syndrome
CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease.
Metabolic Syndrome
CLOCK Gene Variation Is Associated with the Incidence of Metabolic Syndrome Modulated by Monounsaturated Fatty Acids.
Metabolic Syndrome
CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids.
Metabolic Syndrome
CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.
Metabolic Syndrome
Correlation between inflammatory markers and impaired circadian clock gene expression in type 2 diabetes mellitus.
Metabolic Syndrome
Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and shifted the circadian oscillation of the hepatic clock and lipid metabolism-related genes in rats fed a high-fat diet.
Metabolic Syndrome
Diabetes and cardiovascular disease: related disorders created by disturbances in the endogenous clock.
Metabolic Syndrome
Dietary supplementation with essence of chicken enhances daily oscillations in plasma glucocorticoid levels and behavioral adaptation to the phase-shifted environmental light-dark cycle in mice.
Metabolic Syndrome
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
Metabolic Syndrome
Effects of altered photoperiod on circadian clock and lipid metabolism in rats.
Metabolic Syndrome
Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: Evidence from association and interaction analysis.
Metabolic Syndrome
Effects of circadian restricted feeding on parameters of metabolic syndrome among healthy subjects.
Metabolic Syndrome
EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock.
Metabolic Syndrome
Experimental dopaminergic neuron lesion at the area of the biological clock pacemaker, suprachiasmatic nuclei (SCN) induces metabolic syndrome in rats.
Metabolic Syndrome
Expression pattern of clock under acute phase-delay of the light/dark cycle in the chicken pineal model.
Metabolic Syndrome
Gene-gene interaction between serotonin transporter (SLC6A4) and clock modulates the risk of metabolic syndrome in rotating shiftworkers.
Metabolic Syndrome
High-fat feeding exerts minimal effects on rhythmic mRNA expression of clock genes in mouse peripheral tissues.
Metabolic Syndrome
Hydrogen sulfide regulates circadian-clock genes in C2C12 myotubes and the muscle of high-fat-diet-fed mice.
Metabolic Syndrome
Influence of menopause on adipose tissue clock gene genotype and its relationship with metabolic syndrome in morbidly obese women.
Metabolic Syndrome
Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects.
Metabolic Syndrome
Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.
Metabolic Syndrome
Modulation by adiponectin of circadian clock rhythmicity in model mice for metabolic syndrome.
Metabolic Syndrome
Peripheral circadian misalignment: contributor to systemic insulin resistance and potential intervention to improve bariatric surgical outcomes.
Metabolic Syndrome
PPARs in Rhythmic Metabolic Regulation and Implications in Health and Disease.
Metabolic Syndrome
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Metabolic Syndrome
Retinoic acid-related orphan receptors ? and ?: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity.
Metabolic Syndrome
Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.
Metabolic Syndrome
Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome.
Metabolic Syndrome
Short-term circadian disruption impairs bile acid and lipid homeostasis in mice.
Metabolic Syndrome
Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-?.
Metabolic Syndrome
The circadian clock component PERIOD2: From molecular to cerebral functions.
Metabolic Syndrome
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Metabolic Syndrome
The Metabolic Syndrome Predicts Longitudinal Changes in Clock Drawing Test Performance in Older Nondemented Hypertensive Individuals.
Metabolic Syndrome
The Role of Circadian Rhythms in the Hypertension of Diabetes Mellitus and the Metabolic Syndrome.
Metabolic Syndrome
The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.
Metabolic Syndrome
Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.
Metabolic Syndrome
Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases.
Metabolic Syndrome
[Alteration of biological rhythms causes metabolic diseases and obesity].
Metabolic Syndrome
[Molecular and genetic aspects of interactions of the circadian clock and the energy-producing substrate metabolism in mammals].
Metrorrhagia
Enzyme activity dot blots: a rapid and convenient assay for acetyltransferase or protein kinase activity immobilized on nitrocellulose.
Microcephaly
A KAT6A variant in a family with autosomal dominantly inherited microcephaly and developmental delay.
Microcephaly
A novel NAA10 p.(R83H) variant with impaired acetyltransferase activity identified in two boys with ID and microcephaly.
Microcephaly
De Novo Nonsense Mutations in KAT6A, a Lysine Acetyl-Transferase Gene, Cause a Syndrome Including Microcephaly and Global Developmental Delay.
Microcephaly
Interstitial 16p13.3 microduplication: case report and critical review of genotype-phenotype correlation.
Microcephaly
Missense NAA20 variants impairing the NatB protein N-terminal acetyltransferase cause autosomal recessive developmental delay, intellectual disability, and microcephaly.
Microcephaly
Novel Causative Variants in DYRK1A, KARS, and KAT6A Associated with Intellectual Disability and Additional Phenotypic Features.
Microcephaly
Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome.
Microphthalmos
A splice donor mutation in NAA10 results in the dysregulation of the retinoic acid signalling pathway and causes Lenz microphthalmia syndrome.
Microphthalmos
NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment.
Microphthalmos
Phenotypic and biochemical analysis of an international cohort of individuals with variants in NAA10 and NAA15.
Migraine Disorders
Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment.
Mouth Neoplasms
Association study of NAT2 gene polymorphism and risk of oral cancer in Southern Punjab, Pakistan.
Mouth Neoplasms
Loss of the clock gene PER2 is associated with cancer development and altered expression of important tumor-related genes in oral cancer.
Mouth Neoplasms
Melatonin inhibits TPA-induced oral cancer cell migration by suppressing matrix metalloproteinase-9 activation through the histone acetylation.
Mouth Neoplasms
Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention.
Mouth Neoplasms
Temporal patterns of lipid peroxidation product formation and antioxidants activity in oral cancer patients.
Movement Disorders
Paroxysmal Movement Disorder and Epilepsy Caused by a De Novo Truncating Mutation in KAT6A.
Movement Disorders
The Development of the Social Functioning Scale for Patients with Parkinson's Disease.
Mucopolysaccharidoses
An acetylated 120-kDa lysosomal transmembrane protein is absent from mucopolysaccharidosis IIIC fibroblasts: a candidate molecule for MPS IIIC.
Mucopolysaccharidoses
Characterization of the biosynthesis, processing and kinetic mechanism of action of the enzyme deficient in mucopolysaccharidosis IIIC.
Mucopolysaccharidoses
Crosstalk between 2 organelles: Lysosomal storage of heparan sulfate causes mitochondrial defects and neuronal death in mucopolysaccharidosis III type C.
Mucopolysaccharidoses
Functional analysis of the HGSNAT gene in patients with mucopolysaccharidosis IIIC (Sanfilippo C Syndrome).
Mucopolysaccharidoses
Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles.
Mucopolysaccharidoses
Molecular characterization of a large group of Mucopolysaccharidosis type IIIC patients reveals the evolutionary history of the disease.
Mucopolysaccharidoses
Mutations in TMEM76* cause mucopolysaccharidosis IIIC (Sanfilippo C syndrome).
Mucopolysaccharidoses
Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.
Mucopolysaccharidoses
Sanfilippo syndrome type C: mutation spectrum in the heparan sulfate acetyl-CoA: alpha-glucosaminide N-acetyltransferase (HGSNAT) gene.
Mucopolysaccharidoses
Update of the spectrum of mucopolysaccharidoses type III in Tunisia: identification of three novel mutations and in silico structural analysis of the missense mutations.
Mucopolysaccharidosis III
Crosstalk between 2 organelles: Lysosomal storage of heparan sulfate causes mitochondrial defects and neuronal death in mucopolysaccharidosis III type C.
Mucopolysaccharidosis III
Molecular characterization of a large group of Mucopolysaccharidosis type IIIC patients reveals the evolutionary history of the disease.
Mucopolysaccharidosis III
Molecular characterization of MPS IIIA, MPS IIIB and MPS IIIC in Tunisian patients.
Mucopolysaccharidosis III
Mutational analysis of the HGSNAT gene in Italian patients with mucopolysaccharidosis IIIC (Sanfilippo C syndrome). Mutation in brief #959. Online.
Mucopolysaccharidosis III
Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model.
Mucopolysaccharidosis III
Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC.
Mucopolysaccharidosis III
Sanfilippo syndrome type C: assay for acetyl-CoA: alpha-glucosaminide N-acetyltransferase in leukocytes for detection of homozygous and heterozygous individuals.
Mucopolysaccharidosis III
Sanfilippo syndrome type C: mutation spectrum in the heparan sulfate acetyl-CoA: alpha-glucosaminide N-acetyltransferase (HGSNAT) gene.
Mucopolysaccharidosis III
Sanfilippo type C disease: clinical findings in four patients with a new variant of mucopolysaccharidosis III.
Multiple Myeloma
Plasmacellular differentiation in extranodal marginal zone B cell lymphomas of the ocular adnexa: an analysis of the neoplastic plasma cell phenotype and its prognostic significance in 136 cases.
Multiple Sclerosis
Association of circadian rhythm genes ARNTL/BMAL1 and CLOCK with multiple sclerosis.
Multiple Sclerosis
Health-related quality of life and its relationship to cognitive and emotional functioning in multiple sclerosis patients.
Multiple Sclerosis
Importance of magnesium depletion with hypofunction of the biological clock in the pathophysiology of headhaches with photophobia, sudden infant death and some clinical forms of multiple sclerosis.
Multiple Sclerosis
Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease.
Multiple Sclerosis
Screening for early cognitive impairment in multiple sclerosis patients using the clock drawing test.
Multiple System Atrophy
A study of five candidate genes in Parkinson's disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism.
Multiple System Atrophy
Suprachiasmatic nucleus in a patient with multiple system atrophy with abnormal circadian rhythm of arginine-vasopressin secretion into plasma.
Muscle Hypotonia
Features of KAT6B-related disorders in a patient with 10q22.1q22.3 deletion.
Muscle Hypotonia
Five new cases of syndromic intellectual disability due to KAT6A mutations: widening the molecular and clinical spectrum.
Muscle Weakness
Quadriceps muscle weakness and atrophy are associated with a differential Epigenetic Profile in Advanced COPD.
Muscular Atrophy
Atypical expression of circadian clock genes in denervated mouse skeletal muscle.
Muscular Atrophy
Differential expression of HDAC and HAT genes in atrophying skeletal muscle.
Muscular Atrophy
Disruptions to the Limb Muscle Core Molecular Clock Coincide with Changes in Mitochondrial Quality Control following Androgen Depletion.
Muscular Atrophy
Myogenin promoter-associated lncRNA Myoparr is essential for myogenic differentiation.
Muscular Diseases
Deep RNA profiling identified clock and molecular clock genes as pathophysiological signatures in collagen VI myopathy.
Muscular Dystrophy, Facioscapulohumeral
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death.
Myelodysplastic Syndromes
Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments.
Myelodysplastic Syndromes
Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.
Myelodysplastic Syndromes
Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics.
Myelodysplastic Syndromes
Mice heterozygous for CREB binding protein are hypersensitive to ?-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.
Myelodysplastic Syndromes
The t(11;16)(q23;p13) translocation in myelodysplastic syndrome fuses the MLL gene to the CBP gene.
Myeloproliferative Disorders
More on Myb in myelofibrosis: molecular analyses of MYB and EP300 in 55 patients with myeloproliferative disorders.
Myocardial Infarction
A Natural p300-Specific Histone Acetyltransferase Inhibitor, Curcumin, in Addition to Angiotensin-Converting Enzyme Inhibitor, Exerts Beneficial Effects on Left Ventricular Systolic Function After Myocardial Infarction in Rats.
Myocardial Infarction
A rhythm method for better health. Being aware of your body clock could help protect you from a heart attack or stroke and let you time your medications for when they'll do the most good.
Myocardial Infarction
Age- and Gender-related Disparities in Primary Percutaneous Coronary Interventions for Acute ST-segment elevation Myocardial Infarction.
Myocardial Infarction
Association of daylight saving time transitions with incidence and in-hospital mortality of myocardial infarction in Finland.
Myocardial Infarction
Circadian clock genes and circadian phenotypes in patients with myocardial infarction.
Myocardial Infarction
Circadian clock genes and myocardial infarction in patients with type 2 diabetes mellitus.
Myocardial Infarction
Circadian Control of Inflammasome Pathways: Implications for Circadian Medicine.
Myocardial Infarction
Circadian variation of blood pressure and the vascular response to asynchronous stress.
Myocardial Infarction
Comparison of results of percutaneous coronary interventions in patients with ST-segment elevation myocardial infarction during routine working hours or off-hours.
Myocardial Infarction
Effect of hyperlipidemia on the expression of circadian genes in apolipoprotein E knock-out atherosclerotic mice.
Myocardial Infarction
Exploring Epigenetic Age in Response to Intensive Relaxing Training: A Pilot Study to Slow Down Biological Age.
Myocardial Infarction
Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling after myocardial infarction in adult mice in vivo.
Myocardial Infarction
Knowledge and attitudes of American physicians and public about medical chronobiology and chronotherapeutics. Findings of two 1996 Gallup surveys.
Myocardial Infarction
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress.
Myocardial Infarction
Modification of the circadian rhythm of onset of acute myocardial infarction by long-term antianginal treatment.
Myocardial Infarction
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
Myocardial Infarction
Period 2 is essential to maintain early endothelial progenitor cell function in vitro and angiogenesis after myocardial infarction in mice.
Myocardial Infarction
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Myocardial Infarction
Rhythm changes of clock genes, apoptosis-related genes and atherosclerosis-related genes in apolipoprotein E knockout mice.
Myocardial Infarction
Sex Differences in Circadian Clock Genes and Myocardial Infarction Susceptibility.
Myocardial Infarction
The Impact of the Circadian Genes CLOCK and ARNTL on Myocardial Infarction.
Myocardial Infarction
The self-employed and the self-driven: two coronary-prone subpopulations from the Zeist study.
Myocardial Infarction
Time Is Like a Clock in My Heart: Implications for Stem Cell Delivery after Myocardial Infarction.
Myocardial Infarction
Time to Reperfusion in ST-Segment Elevation Acute Myocardial Infarction: When Does the Clock Start?
Myocardial Ischemia
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes.
Myocardial Ischemia
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress.
Myocarditis
Histone deacetylase inhibitors suppress coxsackievirus B3 growth in vitro and myocarditis induced in mice.
Myoclonic Epilepsy, Juvenile
PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.
Myopia
Assessment of Retinal Nerve Fiber Layer Changes by Cirrus High-definition Optical Coherence Tomography in Myopia.
Myopia
Characteristics of sixty myopic eyes with pre-laser in situ keratomileusis retinal examination and post-laser in situ keratomileusis retinal lesions.
Myopia
Pneumatic retinopexy: a survey of current practice patterns among the vitreous society members.
Myopia
Retinal nerve fiber layer measurements in myopia: An optical coherence tomography study.
Myopia
Time to Unplanned Return to the Operating Room and Associated Risk Factors in Patients With Surgical Retinal Detachment Repair.
Narcolepsy
Clock gene polymorphisms and narcolepsy in positive and negative HLA-DQB1*0602 patients.
Narcolepsy
Dynamics of the pituitary-adrenal ensemble in hypocretin-deficient narcoleptic humans: blunted basal adrenocorticotropin release and evidence for normal time-keeping by the master pacemaker.
Nasopharyngeal Carcinoma
Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways.
Nasopharyngeal Carcinoma
The circadian clock gene PER2 enhances chemotherapeutic efficacy in nasopharyngeal carcinoma when combined with a targeted nanosystem.
Nasopharyngeal Carcinoma
The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1?.
Nasopharyngeal Neoplasms
Histone acetyltransferase 1 up regulates Bcl2L12 expression in nasopharyngeal cancer cells.
Neoplasm Metastasis
A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer.
Neoplasm Metastasis
Aberrant expression of clock gene period1 and its correlations with the growth, proliferation and metastasis of buccal squamous cell carcinoma.
Neoplasm Metastasis
Angiopoietin-like protein 4 is a chromatin-bound protein that enhances mammosphere formation in vitro and experimental triple-negative breast cancer brain and liver metastases in vivo.
Neoplasm Metastasis
Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase.
Neoplasm Metastasis
ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.
Neoplasm Metastasis
Brachmann-Cornelia de Lange syndrome with a papilloma of the choroid plexus: analyses of molecular genetic characteristics of the patient and the tumor. A single-case study.
Neoplasm Metastasis
BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300.
Neoplasm Metastasis
Circadian clock gene Per2 downregulation in non?small cell lung cancer is associated with tumour progression and metastasis.
Neoplasm Metastasis
Circadian regulation of cancer cell and tumor microenvironment crosstalk.
Neoplasm Metastasis
Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney.
Neoplasm Metastasis
Disruption of clock gene expression in human colorectal liver metastases.
Neoplasm Metastasis
Down-regulation of Tip60 gene as a potential marker for the malignancy of colorectal cancer.
Neoplasm Metastasis
Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review.
Neoplasm Metastasis
EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
Neoplasm Metastasis
EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.
Neoplasm Metastasis
EP300-A miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas.
Neoplasm Metastasis
FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner.
Neoplasm Metastasis
Identification of a novel microRNA profile including miR-106b, miR-17, miR-20b, miR-18a and miR-93 in the metastasis of nasopharyngeal carcinoma.
Neoplasm Metastasis
Identification of genetic mutations related to invasion and metastasis of acral melanoma via whole-exome sequencing.
Neoplasm Metastasis
Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progression.
Neoplasm Metastasis
Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity.
Neoplasm Metastasis
Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity.
Neoplasm Metastasis
KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer.
Neoplasm Metastasis
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Neoplasm Metastasis
LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein.
Neoplasm Metastasis
Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
Neoplasm Metastasis
Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1? interaction with p300.
Neoplasm Metastasis
N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines.
Neoplasm Metastasis
NAT1 promotes osteolytic metastasis in luminal breast cancer by regulating the bone metastatic niche via NF-?B/IL-1B signaling pathway.
Neoplasm Metastasis
NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1?- and AP-1-mediated VEGFa transcription.
Neoplasm Metastasis
Non-Metastatic Cutaneous Melanoma Induces Chronodisruption in Central and Peripheral Circadian Clocks.
Neoplasm Metastasis
Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma.
Neoplasm Metastasis
Oncogenic EP300 can be targeted with inhibitors of aldo-keto reductases.
Neoplasm Metastasis
PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.
Neoplasm Metastasis
Perspectives on the Role of Histone Modification in Breast Cancer Progression and the Advanced Technological Tools to Study Epigenetic Determinants of Metastasis.
Neoplasm Metastasis
Primary limbal stem cell transplantation in the surgical management of extensive ocular surface squamous neoplasia involving the limbus.
Neoplasm Metastasis
Role of Tip60 in Human Melanoma Cell Migration, Metastasis, and Patient Survival.
Neoplasm Metastasis
Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer.
Neoplasm Metastasis
Small molecule nAS-E targeting cAMP response element binding protein (CREB) and CREB-binding protein interaction inhibits breast cancer bone metastasis.
Neoplasm Metastasis
The circadian clock and hypoxia in tumor cell de-differentiation and metastasis.
Neoplasm Metastasis
TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.
Neoplasm Metastasis
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Neoplasm Metastasis
Tip60-dependent acetylation of KDM2B promotes osteosarcoma carcinogenesis.
Neoplasm Metastasis
Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes.
Neoplasm Metastasis
Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma.
Neoplasms
"Curcumin, the King of Spices": Epigenetic Regulatory Mechanisms in the Prevention of Cancer, Neurological, and Inflammatory Diseases.
Neoplasms
"US-JAPAN CONFERENCE: INFLAMMATION, DIABETES AND CANCER" held at the Beckman Research Institute of City of Hope, Duarte, CA, USA.
Neoplasms
'Comparison of extremes' approach provides evidence against the modifying role of NAT2 polymorphism in lung cancer susceptibility.
Neoplasms
2-Aminofluorene-DNA adduct levels in tumor-target and nontarget organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus.
Neoplasms
24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins.
Neoplasms
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
Neoplasms
?-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Neoplasms
A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line.
Neoplasms
A circadian clock transcription model for the personalization of cancer chronotherapy.
Neoplasms
A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets.
Neoplasms
A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine.
Neoplasms
A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation.
Neoplasms
A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb.
Neoplasms
A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.
Neoplasms
A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo.
Neoplasms
A Nobel-Winning Scientist: Aziz Sancar and the Impact of his Work on the Molecular Pathology of Neoplastic Diseases.
Neoplasms
A novel low-cost method for assessing intra-urban variation in night time light and applications to public health.
Neoplasms
A novel mutation lacking the bromodomain of the transcriptional coactivator p300 in the SiHa cervical carcinoma cell line.
Neoplasms
A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, and regeneration.
Neoplasms
A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer.
Neoplasms
A review of oral transmucosal fentanyl citrate: potent, rapid and noninvasive opioid analgesia.
Neoplasms
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
Neoplasms
A Systems Biology Comparison of Ovarian Cancers Implicates Putative Somatic Driver Mutations through Protein-Protein Interaction Models.
Neoplasms
A Systems-Level Analysis Reveals Circadian Regulation of Splicing in Colorectal Cancer.
Neoplasms
Aberrant expression of the tyrosine kinase receptor EphA4 and the transcription factor twist in Sézary syndrome identified by gene expression analysis.
Neoplasms
Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics.
Neoplasms
Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer.
Neoplasms
Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer.
Neoplasms
Acetylation of XPF by TIP60 facilitates XPF-ERCC1 complex assembly and activation.
Neoplasms
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer.
Neoplasms
Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.
Neoplasms
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin-9.
Neoplasms
Acute systemic inflammation transiently synchronizes clock gene expression in equine peripheral blood.
Neoplasms
Ad E1A 243R oncoprotein promotes association of proto-oncogene product MYC with the NuA4/Tip60 complex via the E1A N-terminal repression domain.
Neoplasms
Adenosine A(2A) Receptor and TNF-? Regulate the Circadian Machinery of the Human Monocytic THP-1 Cells.
Neoplasms
Adjusting the Molecular Clock: The Importance of Circadian Rhythms in the Development of Glioblastomas and Its Intervention as a Therapeutic Strategy.
Neoplasms
Age-associated risk of cancer among individuals with N-acetyltransferase 2 (NAT2) mutations and mutations in DNA mismatch repair genes.
Neoplasms
Allele frequencies for glutathione S-transferase and N-acetyltransferase 2 differ in African population groups and may be associated with oesophageal cancer or tuberculosis incidence.
Neoplasms
ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition.
Neoplasms
Alteration of microRNA-4474/4717 expression and CREB-binding protein in human colorectal cancer tissues infected with Fusobacterium nucleatum.
Neoplasms
Alterations of sleep quality and circadian rhythm genes expression in elderly thyroid nodule patients and risks associated with thyroid malignancy.
Neoplasms
Altered circadian genes expression in breast cancer tissue according to the clinical characteristics.
Neoplasms
Altered Circadian Rhythms and Breast Cancer: From the Human to the Molecular Level.
Neoplasms
Altered expression of circadian clock genes in head and neck squamous cell carcinoma.
Neoplasms
Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors.
Neoplasms
Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery.
Neoplasms
Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load.
Neoplasms
An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets.
Neoplasms
An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells.
Neoplasms
An Optimal Time for Treatment-Predicting Circadian Time by Machine Learning and Mathematical Modelling.
Neoplasms
An Overview of the Polymorphisms of Circadian Genes Associated With Endocrine Cancer.
Neoplasms
An unlikely role for the NAT2 genotypes and haplotypes in the oral cancer of south Indians.
Neoplasms
Analysis of clock gene-miRNA correlation networks reveals candidate drivers in colorectal cancer.
Neoplasms
Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.
Neoplasms
Analysis of incomplete excisions of basal-cell carcinomas after breadloaf microscopy compared with 3D-microscopy: a prospective randomized and blinded study.
Neoplasms
Analysis of mRNA Expression Patterns in Peripheral Blood Cells of 3 Patients With Cancer After the First Fraction of 2 Gy Irradiation: An Integrated Case Report and Systematic Review.
Neoplasms
Analysis of the Circadian Regulation of Cancer Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington's Disease.
Neoplasms
Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells.
Neoplasms
Aptamer-mediated rolling circle amplification for label-free and sensitive detection of histone acetyltransferase activity.
Neoplasms
ARNTL2 knockdown suppressed the invasion and migration of colon carcinoma: decreased SMOC2-EMT expression through inactivation of PI3K/AKT pathway.
Neoplasms
Aromatic DNA adducts in coke-oven workers, in relation to exposure, lifestyle and genetic polymorphism of metabolic enzymes.
Neoplasms
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation.
Neoplasms
Arrest defective-1 controls tumor cell behavior by acetylating myosin light chain kinase.
Neoplasms
Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-X(L) and survivin.
Neoplasms
Arylamine N-acetyltransferase activity and 2 aminofluorene-DNA adducts formation in rat glial tumor cells.
Neoplasms
ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.
Neoplasms
Association between CLOCK, PER3 and CCRN4L with non?small cell lung cancer in Brazilian patients.
Neoplasms
Association between N-acetyltransferase 2 (NAT2) genetic polymorphism and development of breast cancer in post-menopausal Chinese women in Taiwan, an area of great increase in breast cancer incidence.
Neoplasms
Association between polymorphisms at N-acetyltransferase 1 (NAT1) & risk of oral leukoplakia & cancer.
Neoplasms
Association of Circadian Clock Gene Expression with Glioma Tumor Microenvironment and Patient Survival.
Neoplasms
Association of Slow Acetylation Profile of NAT2 with Breast and Gastric Cancer Risk in Brazil.
Neoplasms
Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis.
Neoplasms
Associations of genetic variants in the transcriptional coactivators EP300 and PCAF with hepatocellular carcinoma.
Neoplasms
Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation.
Neoplasms
Axin determines cell fate by controlling the p53 activation threshold after DNA damage.
Neoplasms
Berberine inhibited arylamine N-acetyltransferase activity and gene expression and DNA adduct formation in human malignant astrocytoma (G9T/VGH) and brain glioblastoma multiforms (GBM 8401) cells.
Neoplasms
Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.
Neoplasms
Bilateral ocular surface squamous neoplasia with bilateral periocular basal cell carcinoma in a case of xeroderma pigmentosum.
Neoplasms
Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis.
Neoplasms
BMAL1 Knockdown Leans Epithelial-Mesenchymal Balance toward Epithelial Properties and Decreases the Chemoresistance of Colon Carcinoma Cells.
Neoplasms
Brachmann-Cornelia de Lange syndrome with a papilloma of the choroid plexus: analyses of molecular genetic characteristics of the patient and the tumor. A single-case study.
Neoplasms
BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways.
Neoplasms
Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development.
Neoplasms
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.
Neoplasms
c-MYC targets the central oscillator gene Per1 and is regulated by the circadian clock at the post-transcriptional level.
Neoplasms
Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase.
Neoplasms
Cancer inhibition through circadian reprogramming of tumor transcriptome with meal timing.
Neoplasms
Cancer stem cell generation during epithelial-mesenchymal transition is temporally gated by intrinsic circadian clocks.
Neoplasms
Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK.
Neoplasms
Case-control study of the PERIOD3 clock gene length polymorphism and colorectal adenoma formation.
Neoplasms
Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NF?B-dependent pathway.
Neoplasms
Cation-? interactions in CREBBP bromodomain inhibition: an electrostatic model for small-molecule binding affinity and selectivity.
Neoplasms
CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells.
Neoplasms
CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.
Neoplasms
CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers.
Neoplasms
CBX4 Provides an Alternate Mode of Colon Cancer Development via Potential Influences on Circadian Rhythm and Immune Infiltration.
Neoplasms
Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth.
Neoplasms
Cellular distribution of N-acetyltransferase activity in the rat small intestine.
Neoplasms
Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast.
Neoplasms
Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.
Neoplasms
Chemotherapy-related cognitive impairment in patients with breast cancer based on MRS and DTI analysis.
Neoplasms
Chidamide and decitabine can synergistically induce apoptosis of Hodgkin lymphoma cells by up-regulating the expression of PU.1 and KLF4.
Neoplasms
Cholecystokinin attenuates radiation-induced lung cancer cell apoptosis by modulating p53 gene transcription.
Neoplasms
Chronic Exposure to Continuous Brightness or Darkness Modulates Immune Responses and Ameliorates the Antioxidant Enzyme System in Male Rats.
Neoplasms
Chrono-Drug Discovery and Development Based on Circadian Rhythm of Molecular, Cellular and Organ Level.
Neoplasms
Chrono-immunology: progress and challenges in understanding links between the circadian and immune systems.
Neoplasms
Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction.
Neoplasms
Chronopharmacological strategies: Intra- and inter-individual variability of molecular clock.
Neoplasms
Circadian alteration in neurobiology during 30 days of abstinence in heroin users.
Neoplasms
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation.
Neoplasms
Circadian clock components ROR? and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells.
Neoplasms
Circadian clock coordinates cancer cell cycle progression, thymidylate synthase, and 5-fluorouracil therapeutic index.
Neoplasms
Circadian Clock Gene Bmal1 Inhibits Tumorigenesis and Increases Paclitaxel Sensitivity in Tongue Squamous Cell Carcinoma.
Neoplasms
Circadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.
Neoplasms
Circadian clock gene expression regulates cancer cell growth through glutaminase.
Neoplasms
Circadian clock gene Per2 downregulation in non?small cell lung cancer is associated with tumour progression and metastasis.
Neoplasms
Circadian clock gene Period2 suppresses human chronic myeloid leukemia cell proliferation.
Neoplasms
Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation.
Neoplasms
Circadian clock genes: Non-circadian roles in sleep, addiction, and psychiatric disorders?
Neoplasms
Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression.
Neoplasms
Circadian clock is associated with tumor microenvironment in kidney renal clear cell carcinoma.
Neoplasms
Circadian clock manipulation for cancer prevention and control and the relief of cancer symptoms.
Neoplasms
Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.
Neoplasms
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Neoplasms
Circadian disruption in cancer: a neuroendocrine-immune pathway from stress to disease?
Neoplasms
Circadian disruption promotes tumor-immune microenvironment remodeling favoring tumor cell proliferation.
Neoplasms
Circadian disruption, sleep loss, and prostate cancer risk: a systematic review of epidemiologic studies.
Neoplasms
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
Neoplasms
Circadian modulation of proteasome activities and removal of carbonylated proteins.
Neoplasms
Circadian modulation of proteasome activity and accumulation of oxidized protein in human embryonic kidney HEK 293 cells and primary dermal fibroblasts.
Neoplasms
Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes.
Neoplasms
Circadian pathway genetic variation and cancer risk: evidence from genome-wide association studies.
Neoplasms
Circadian regulation of cell cycle: Molecular connections between aging and the circadian clock.
Neoplasms
Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment.
Neoplasms
Circadian rhythm genes in cancer: insight into their functions and regulation involving noncoding RNAs.
Neoplasms
Circadian rhythm of tumor promotion in the two-stage model of mouse tumorigenesis.
Neoplasms
Circadian rhythms of factors involved in luteal regression are modified in p55 tumour necrosis factor receptor (TNFRp55)-deficient mice.
Neoplasms
Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex.
Neoplasms
Circadian transcription profile of mouse breast cancer under light-dark and dark-dark conditions.
Neoplasms
Circadian variations of clock gene Per2 and cell cycle genes in different stages of carcinogenesis in golden hamster buccal mucosa.
Neoplasms
CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis.
Neoplasms
Clock and ATF4 transcription system regulates drug resistance in human cancer cell lines.
Neoplasms
CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells.
Neoplasms
Clock dial integrated positioning combined with single utility port video-assisted thoracoscopic surgery: a new localization method for lung tumors.
Neoplasms
Clock gene expression levels and relationship with clinical and pathological features in colorectal cancer patients.
Neoplasms
Clock gene modulation by TNF-alpha depends on calcium and p38 MAP kinase signaling.
Neoplasms
CLOCK in breast tumorigenesis: genetic, epigenetic, and transcriptional profiling analyses.
Neoplasms
CLOCK is a substrate of SUMO and sumoylation of CLOCK upregulates the transcriptional activity of estrogen receptor-?
Neoplasms
Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation.
Neoplasms
Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney.
Neoplasms
Combination of lentivirus-mediated silencing of PPM1D and temozolomide chemotherapy eradicates malignant glioma through cell apoptosis and cell cycle arrest.
Neoplasms
Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP.
Neoplasms
Combined analysis of polymorphisms of the tumor necrosis factor-alpha and interleukin-10 promoter regions and polymorphic xenobiotic metabolizing enzymes in psoriasis.
Neoplasms
Combined hamartoma of the retina and retinal pigment epithelium in 77 consecutive patients visual outcome based on macular versus extramacular tumor location.
Neoplasms
Combined inhibition of heat shock proteins 90 and 70 leads to simultaneous degradation of the oncogenic signaling proteins involved in muscle invasive bladder cancer.
Neoplasms
Combined Targeting of the BRD4-NUT-p300 Axis in NUT Midline Carcinoma by Dual Selective Bromodomain Inhibitor, NEO2734.
Neoplasms
Concomitant Simple Limbal Epithelial Transplantation After Surgical Excision of Ocular Surface Squamous Neoplasia.
Neoplasms
Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.
Neoplasms
Consistency of observations from echograms made centrally in the Collaborative Ocular Melanoma Study COMS Report No. 13.
Neoplasms
Constitutional trisomy 8p11.21-q11.21 mosaicism: a germline alteration predisposing to myeloid leukaemia.
Neoplasms
Construction of a plasmid for overexpression of human circadian gene period2 and its biological activity in osteosarcoma cells.
Neoplasms
Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1? protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Müller) cells.
Neoplasms
Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.
Neoplasms
Cooperative interaction among BMAL1, HSF1, and p53 protects mammalian cells from UV stress.
Neoplasms
Correction to: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Neoplasms
Correlated downregulation of estrogen receptor beta and the circadian clock gene Per1 in human colorectal cancer.
Neoplasms
Correlation between deregulated expression of PER2 gene and degree of glioma malignancy.
Neoplasms
Correlation of Inflammation in Frozen Sections With Site of Nonmelanoma Skin Cancer.
Neoplasms
Corrigendum: Exploiting the Circadian Clock for Improved Cancer Therapy: Perspective From a Cell Biologist.
Neoplasms
Coupling between the Circadian Clock and Cell Cycle Oscillators: Implication for Healthy Cells and Malignant Growth.
Neoplasms
CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma.
Neoplasms
CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein.
Neoplasms
CREBBP knockdown suppressed proliferation and promoted chemo-sensitivity via PERK-mediated unfolded protein response in ovarian cancer.
Neoplasms
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition.
Neoplasms
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis.
Neoplasms
Cross-talks between circadian timing system and cell division cycle determine cancer biology and therapeutics.
Neoplasms
Cry 1 Regulates the Clock Gene Network and Promotes Proliferation and Migration Via the Akt/P53/P21 Pathway in Human Osteosarcoma Cells.
Neoplasms
Curcumin decreases the DNA adduct formation, arylamines N-acetyltransferase activity and gene expression in human colon tumor cells (colo 205).
Neoplasms
Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells.
Neoplasms
Curcumin: a therapeutic strategy in cancers by inhibiting the canonical WNT/?-catenin pathway.
Neoplasms
Current Status of Research on the Period Family of Clock Genes in the Occurrence and Development of Cancer.
Neoplasms
Custom-designed plaque radiotherapy for nonresectable iris melanoma in 38 patients: tumor control and ocular complications.
Neoplasms
CVID-Associated Tumors: Czech Nationwide Study Focused on Epidemiology, Immunology, and Genetic Background in a Cohort of Patients With CVID.
Neoplasms
Cytochrome P450 (CYP) 1A2, sulfotransferase (SULT) 1A1, and N-acetyltransferase (NAT) 2 polymorphisms and susceptibility to urothelial cancer.
Neoplasms
Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications.
Neoplasms
Daily rhythm variations of the clock gene PER1 and cancer-related genes during various stages of carcinogenesis in a golden hamster model of buccal mucosa carcinoma.
Neoplasms
Daily rhythms are retained both in spontaneously developed sarcomas and in xenografts grown in immunocompromised SCID mice.
Neoplasms
Daily timed meals dissociate circadian rhythms in hepatoma and healthy host liver.
Neoplasms
Deciphering the Binding Mode and Mechanistic Insights of Pentadecylidenemalonate (1b) as Activator of Histone Acetyltransferase PCAF.
Neoplasms
Decreased circadian component Bmal1 predicts tumor progression and poor prognosis in human pancreatic ductal adenocarcinoma.
Neoplasms
Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas.
Neoplasms
Deficiency in PER proteins has no effect on the rate of spontaneous and radiation-induced carcinogenesis.
Neoplasms
Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality.
Neoplasms
Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors.
Neoplasms
Deregulation of signaling pathways controlling cell survival and proliferation in cancer cells alters induction of cytochrome P450 family 1 enzymes.
Neoplasms
Deregulation of the circadian clock constitutes a significant factor in tumorigenesis: a clockwork cancer. Part I: clocks and clocking machinery.
Neoplasms
Deregulation of the circadian clock constitutes a significant factor in tumorigenesis: a clockwork cancer. Part II. In vivo studies.
Neoplasms
Design and synthesis of selective, small molecule inhibitors of coactivator-associated arginine methyltransferase 1 (CARM1).
Neoplasms
Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors.
Neoplasms
Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway.
Neoplasms
Desynchronization of Circadian Clocks in Cancer: A Metabolic and Epigenetic Connection.
Neoplasms
Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells.
Neoplasms
Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathway.
Neoplasms
Development of transgenic minipigs with expression of antimorphic human cryptochrome 1.
Neoplasms
Diallyl disulfide inhibits N-acetyltransferase activity and gene expression in human esophagus epidermoid carcinoma CE 81T/VGH cells.
Neoplasms
Dietary supplementation with essence of chicken enhances daily oscillations in plasma glucocorticoid levels and behavioral adaptation to the phase-shifted environmental light-dark cycle in mice.
Neoplasms
Dietary, metabolic, and potentially environmental modulation of the lysine acetylation machinery.
Neoplasms
Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.
Neoplasms
Differences in N-acetylation genotypes between Caucasians and Black South Africans: implications for cancer prevention.
Neoplasms
Different roles of negative and positive components of the circadian clock in oncogene-induced neoplastic transformation.
Neoplasms
Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells.
Neoplasms
Differential Expression of Circadian Genes in Leukemia and a Possible Role for Sirt1 in Restoring the Circadian Clock in Chronic Myeloid Leukemia.
Neoplasms
Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A.
Neoplasms
Differential expression of selected histone modifier genes in human solid cancers.
Neoplasms
Differential mRNA expression levels of human histone-modifying enzymes in normal karyotype B cell pediatric acute lymphoblastic leukemia.
Neoplasms
DIFFUSE PERIPAPILLARY CHOROIDAL MELANOMA THAT EVOLVED FROM A SMALL PRESUMED CHOROIDAL NEVUS SUCCESSFULLY TREATED WITH GAMMA KNIFE RADIOTHERAPY.
Neoplasms
Discordance between N-acetyltransferase 2 phenotype and genotype in a population of Hmong subjects.
Neoplasms
Discovery and characterization of NK13650s, naturally occurring p300-selective histone acetyltransferase inhibitors.
Neoplasms
Discovery and mechanism of natural products as modulators of histone acetylation.
Neoplasms
Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.
Neoplasms
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe.
Neoplasms
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Neoplasms
Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor.
Neoplasms
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening.
Neoplasms
Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases.
Neoplasms
Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice.
Neoplasms
Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes.
Neoplasms
Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors.
Neoplasms
Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis.
Neoplasms
Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2.
Neoplasms
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas.
Neoplasms
DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.
Neoplasms
DNA methylation loss in late-replicating domains is linked to mitotic cell division.
Neoplasms
Double recording system of Period1 gene expression rhythm in the olfactory bulb and liver in freely moving mouse.
Neoplasms
Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm.
Neoplasms
Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF.
Neoplasms
Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.
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Down-regulation of Tip60 gene as a potential marker for the malignancy of colorectal cancer.
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Downregulation of CREB-binding protein expression sensitizes endothelial cells to serum-deprived apoptosis: important role of nitric oxide.
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Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis.
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Dysregulation, functional implications, and prognostic ability of the circadian clock across cancers.
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E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60.
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E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain.
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Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors.
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Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) or 2-amino-3,8- dimethylimidazo- [4,5-f] quinoxaline (MeIQx).
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Effect of strain differences and tumor presence on microsomal drug metabolism in the guinea pig: brief communication.
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Effect of the Interaction Between Cadmium Exposure and CLOCK Gene Polymorphisms on Thyroid Cancer: a Case-Control Study in China.
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Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review.
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Effects and mechanisms of action of light-emitting diodes on the human retina and internal clock.
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Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice.
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Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.
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Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity.
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Effects of the butylated hydroxyanisole and butylated hydroxytoluene on the DNA adduct formation and arylamines N-acetyltransferase activity in human colon tumor cells.
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Efficient AuPd@GO-based electrochemical nanoprobe for sensitive detection of histone acetylase activity and its inhibitor.
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Endogenous synthesis of peptidoglycan in eukaryotic cells; a novel concept involving its essential role in cell division, tumor formation and the biological clock.
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Enhanced MYC association with the NuA4 histone acetyltransferase complex mediated by the adenovirus E1A N-terminal domain activates a subset of MYC target genes highly expressed in cancer cells.
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Enhancer of Polycomb and the Tip60 complex repress hematological tumor initiation by negatively regulating JAK/STAT pathway activity.
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EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinoma.
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EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.
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EP300 mutation is associated with tumor mutation burden and promotes antitumor immunity in bladder cancer patients.
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EP300-A miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas.
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Epigenetic Age Acceleration of Stomach Adenocarcinoma Associated With Tumor Stemness Features, Immunoactivation, and Favorable Prognosis.
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Epigenetic age acceleration predicts cancer, cardiovascular, and all-cause mortality in a German case cohort.
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Epigenetic change in kidney tumor: downregulation of histone acetyltransferase MYST1 in human renal cell carcinoma.
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Epigenetic inactivation of the circadian clock gene BMAL1 in hematologic malignancies.
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Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review.
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Epigenetics provides a new generation of oncogenes and tumour-suppressor genes.
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Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics.
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Establishment and Verification of a Bagged-Trees-Based Model for Prediction of Sentinel Lymph Node Metastasis for Early Breast Cancer Patients.
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Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia.
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Evaluation of multidrug cancer chronotherapy based on cell cycle model under influences of circadian clock.
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Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells.
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Evidence for widespread dysregulation of circadian clock progression in human cancer.
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Evidence that the acetyltransferase Tip60 induces the DNA damage response and cell-cycle arrest in neonatal cardiomyocytes.
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EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function.
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Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.
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Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
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Exploiting the Circadian Clock for Improved Cancer Therapy: Perspective From a Cell Biologist.
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Exploring the link between chronobiology and drug delivery: effects on cancer therapy.
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Exploring the role of circadian clock gene and association with cancer pathophysiology.
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Expression and Prognostic Significance of EP300, TP53 and BAX in Clear Cell Renal Cell Carcinoma.
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Expression of cell cycle regulatory factors hus1, gadd45a, rb1, cdkn2a and mre11a correlates with expression of clock gene per2 in human colorectal carcinoma tissue.
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Expression of circadian clock genes and proteins in urothelial cancer is related to cancer-associated genes.
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Expression of Circadian Clock Genes in Human Colorectal Cancer Tissues Using Droplet Digital PCR.
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Expression of circadian genes correlates with liver metastasis and outcomes in colorectal cancer.
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Expression of clock genes cry1 and cry2 in human colorectal cancer and tumor adjacent tissues correlates with location of tumor differently.
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Expression of core clock genes in colorectal tumour cells compared with normal mucosa; a systematic review of clinical trials.
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Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression.
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Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.
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Expression of PCAF, p300 and Gcn5 and more highly acetylated histone H4 in pediatric tumors.
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Expression of the Circadian Clock Gene BMAL1 Positively Correlates With Antitumor Immunity and Patient Survival in Metastatic Melanoma.
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Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors.
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Expression pattern and prognostic value of circadian clock genes in pancreatic adenocarcinoma.
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Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model.
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Fe65 Suppresses Breast Cancer Cell Migration and Invasion through Tip60 Mediated Cortactin Acetylation.
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Feasibility of quantifying the effects of epoetin alfa therapy on cognitive function in women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy.
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Frameshift mutations of tumor suppressor gene EP300 in gastric and colorectal cancers with high microsatellite instability.
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Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.
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Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.
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Functional characterization of the A411T (L137F) and G364A (D122N) genetic polymorphisms in human N-acetyltransferase 2.
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Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3' untranslated regions.
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Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1.
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G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review].
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Gaps in the Use of Long-Acting Opioids Within Intervals of Consecutive Days Among Cancer Outpatients Using Electronic Pill Caps.
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Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Non-Homologous End Joining.
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Garcinol-A Natural Histone Acetyltransferase Inhibitor and New Anti-Cancer Epigenetic Drug.
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GCN5 inhibition prevents IL-6-induced prostate cancer metastases through PI3K/PTEN/Akt signaling by inactivating Egr-1.
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Gender-specific associations between polymorphisms of the circadian gene RORA and cutaneous melanoma susceptibility.
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Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer.
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Genetic alterations and oncogenic pathways associated with breast cancer subtypes.
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Genetic and clinical heterogeneity in Korean patients with Rubinstein-Taybi syndrome.
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Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias.
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Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer.
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Genetic polymorphism of N-acetyltransferase and glutathione S-transferase related to neoplasm of genitourinary system. Minireview.
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Genetic polymorphism of the N-acetyltransferase 2 gene, and susceptibility to prostate cancer: a pilot study in north Indian population.
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Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response.
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Genetic regulation of N-acetyltransferase in target organs of arylamine tumors: homologous expression in human and hamster bladder and colon.
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Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
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Genome-wide somatic copy number alteration analysis and database construction for cervical cancer.
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Genomic alterations in advanced gastric cancer endoscopic biopsy samples using targeted next-generation sequencing.
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Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.
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Genotypes of glutathione S-transferase M1 and N-acetyltransferase 2 in Japanese patients with gastric cancer.
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Genotyping of the polymorphic N-acetyltransferase (NAT2) and loss of heterozygosity in bladder cancer patients.
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Glioma-induced SIRT1-dependent activation of hMOF histone H4 lysine 16 acetyltransferase in microglia promotes a tumor supporting phenotype.
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Global co-distribution of light at night (LAN) and cancers of prostate, colon, and lung in men.
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Glucose Restriction Combined with Autophagy Inhibition and Chemotherapy in HCT 116 Spheroids Decreases Cell Clonogenicity and Viability Regulated by Tumor Suppressor Genes.
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Glutathione S-transferase (GST) M1, T1 and N-acetyltransferase 2 (NAT2) polymorphisms and urothelial cancer risk with tobacco smoking.
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Haploinsufficient tumor suppressor Tip60 negatively regulates oncogenic Aurora B kinase.
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Has the era of individualised medicine arrived for antifungals? A review of antifungal pharmacogenomics.
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Heparanase-mediated Loss of Nuclear Syndecan-1 Enhances Histone Acetyltransferase (HAT) Activity to Promote Expression of Genes That Drive an Aggressive Tumor Phenotype.
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Hepatitis B virus X protein disrupts the balance of the expression of circadian rhythm genes in hepatocellular carcinoma.
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High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints.
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Highly aggressive undifferentiated small round blue cell tumor of foot with unique SMARCA1, KAT6A and NAV3 mutations.
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Histone acetyltransferase 1 upregulates androgen receptor expression to modulate CRPC cell resistance to enzalutamide.
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Histone acetyltransferase Hbo1 destabilizes estrogen receptor ? by ubiquitination and modulates proliferation of breast cancers.
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Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers.
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Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.
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Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.
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Histone acetyltransferase MOZ acts as a co-activator of Nrf2-MafK and induces tumour marker gene expression during hepatocarcinogenesis.
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Histone acetyltransferase p300 mediates the upregulation of CTEN induced by the activation of EGFR signaling in cancer cells.
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Histone Acetyltransferase PCAF Is Required for Hedgehog-Gli-Dependent Transcription and Cancer Cell Proliferation.
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Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation.
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Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy.
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Histone deacetylase inhibitors in malignant pleural mesothelioma: preclinical rationale and clinical trials.
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Histone deacetylase inhibitors induce the expression of tumor suppressor genes Per1 and Per2 in human gastric cancer cells.
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Histone deacetylase inhibitors: a new wave of molecular targeted anticancer agents.
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Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review).
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Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.
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Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.
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Host-Viral Interactions Revealed among Shared Transcriptomics Signatures of ARDS and Thrombosis: A Clue into COVID-19 Pathogenesis.
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Human immunodeficiency virus type-1 Tat/co-activator acetyltransferase interactions inhibit p53Lys-320 acetylation and p53-responsive transcription.
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Human papillomavirus and the landscape of secondary genetic alterations in oral cancers.
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Human peripheral clocks: applications for studying circadian phenotypes in physiology and pathophysiology.
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Hypermethylation of N-Acetyltransferase 1 Is a Prognostic Biomarker in Colon Adenocarcinoma.
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Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin.
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Identification and meta-analysis of copy number variation-driven circadian clock genes for colorectal cancer.
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Identification of a panel of MYC and Tip60 co-regulated genes functioning primarily in cell cycle and DNA replication.
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Identification of molecular features correlating with tumor immunity in gastric cancer by multi-omics data analysis.
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Identification of MYST3 as a novel epigenetic activator of ER? frequently amplified in breast cancer.
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Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein.
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Identification of prognostic molecular biomarkers in 157 HPV-positive and HPV-negative squamous cell carcinomas of the oropharynx.
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Identification of valid reference genes for circadian gene-expression studies in human mammary epithelial cells.
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IDH1 gene mutation activates Smad signaling molecules to regulate the expression levels of cell cycle and biological rhythm genes in human glioma U87?MG cells.
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Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo.
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Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity.
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Impact of chronically alternating light-dark cycles on circadian clock mediated expression of cancer (glioma)-related genes in the brain.
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Implications of circadian clocks for the rhythmic delivery of cancer therapeutics.
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Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative.
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Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor.
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Improvement of sensitivity to platinum compound with siRNA knockdown of upregulated genes in platinum complex-resistant ovarian cancer cells in vitro.
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In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation.
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Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth.
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Inactivation of human arylamine N-acetyltransferase 1 by the hydroxylamine of p-aminobenzoic acid.
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Incompatibility of the circadian protein BMAL1 and HNF4? in hepatocellular carcinoma.
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Increased p300/CBP expression in acute respiratory distress syndrome is associated with interleukin-17 and prognosis.
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Induction of NKG2D ligand expression on tumor cells by CD8+ T-cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor.
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Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8(+) T Cells and Histone Acetyltransferases.
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Induction of transcription through the p300 CRD1 motif by p21WAF1/CIP1 is core promoter specific and cyclin dependent kinase independent.
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ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells.
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ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.
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Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest.
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Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice.
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Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo.
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Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation.
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Inhibition of histone deacetylases in melanoma-a perspective from bench to bedside.
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Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells.
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Inhibition of N-acetyltransferase 10 using remodelin attenuates doxorubicin resistance by reversing the epithelial-mesenchymal transition in breast cancer.
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Inhibition of N-acetyltransferase activity and DNA-2-aminofluorene adducts by glycyrrhizic acid in human colon tumour cells.
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Inhibition of NAT10 Suppresses Melanogenesis and Melanoma Growth by Attenuating Microphthalmia-Associated Transcription Factor (MITF) Expression.
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Inhibition of p300 impairs Foxp3(+) T regulatory cell function and promotes antitumor immunity.
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Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines.
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Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi's Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells.
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Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice.
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Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity.
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Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
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Inhibitory effects of the mitogen-activated protein kinase kinase inhibitor CI-1040 on the proliferation and tumor growth of thyroid cancer cells with BRAF or RAS mutations.
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Insights into interaction mechanism of inhibitors E3T, E3H and E3B with CREB binding protein by using molecular dynamics simulations and MM-GBSA calculations.
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Integrative Analysis Reveals Comprehensive Altered Metabolic Genes Linking with Tumor Epigenetics Modification in Pan-Cancer.
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Interferon Alfa 2b for Ocular Surface Squamous Neoplasia: Factors Influencing the Treatment Response.
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Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects.
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Interplay between chromatin-modifying enzymes controls colon cancer progression through Wnt signaling.
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Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment.
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Intraocular medulloepithelioma - A review of clinical features, DICER 1 mutation, and management.
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Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2.
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Inverse correlation between Naa10p and Pirh2 expression and the combined prognostic value in oral squamous cell carcinoma patients.
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Involvement of RFX1 protein in the regulation of the human proliferating cell nuclear antigen promoter.
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Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes: The ABCDEF Guide.
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Isolated cardiac recurrence of acute lymphoblastic leukemia characterized by t(11;19) two years after unrelated allogeneic bone marrow transplantation.
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It's About Time: Advances in Understanding the Circadian Regulation of DNA Damage and Repair in Carcinogenesis and Cancer Treatment Outcomes.
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KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
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KAT2B is an immune infiltration-associated biomarker predicting prognosis and response to immunotherapy in non-small cell lung cancer.
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KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2.
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KAT5 and KAT6B are in positive regulation on cell proliferation of prostate cancer through PI3K-AKT signaling.
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KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer.
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KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma.
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KAT6A, a chromatin modifier from the 8p11-p12 amplicon is a candidate oncogene in luminal breast cancer.
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KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.
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Ketoprofen-inhibited N-acetyltransferase activity and gene expression in human colon tumor cells.
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KIF11 promotes cell proliferation via ERBB2/PI3K/AKT signaling pathway in gallbladder cancer.
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Knockdown of MIR9?3HG inhibits proliferation and promotes apoptosis of cervical cancer cells by miR?498 via EP300.
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Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3.
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Lack of Association of the N-acetyltransferase NAT1*10 Allele with Prostate Cancer Incidence, Grade, or Stage Among Smokers in Finland.
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Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.
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Life expectancy for a class of life distributions having the "setting the clock back to zero" property.
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Lifting Up the HAT: Synthetic Lethal Screening Reveals a Novel Vulnerability at the CBP-p300 Axis.
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Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations.
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Light exposure at night disrupts host/cancer circadian regulatory dynamics: impact on the Warburg effect, lipid signaling and tumor growth prevention.
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Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents.
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Long-term outcomes after enucleation or plaque brachytherapy of choroidal melanomas touching the optic disc.
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Loss of circadian clock gene expression is associated with tumor progression in breast cancer.
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Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy.
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Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway.
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Loss of the clock gene PER2 is associated with cancer development and altered expression of important tumor-related genes in oral cancer.
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Low circadian clock genes expression in cancers: A meta-analysis of its association with clinicopathological features and prognosis.
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LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype.
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Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
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Lysine Acetyltransferase GCN5 Potentiates the Growth of Non-Small Cell Lung Cancer via Promotion of E2F1, Cyclin D1 and Cyclin E1 Expression.
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Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.
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MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation.
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Make the right measurement: Discovery of an allosteric inhibition site for p300-HAT.
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Mammalian circadian biology: elucidating genome-wide levels of temporal organization.
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Mammary tumors compromise time-of-day differences in hypothalamic gene expression and circadian behavior and physiology in mice.
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Mapping the Interactions of the p53 Transactivation Domain with the KIX Domain of CBP (dagger).
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Mechanism of p300 specific histone acetyltransferase inhibition by small molecules.
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Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies.
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Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1? interaction with p300.
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Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer.
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Metachronous carcinogenesis of superficial esophagus squamous cell carcinoma after endoscopic submucosal dissection: incidence and risk stratification during long-term observation.
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Metagenomic characterization of KATs in human cancer and their association with clinic-pathological features.
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Methods for monitoring the functional status of the circadian system in dietary surveys studies: application criteria and interpretation of results.
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Methyl deficiency, alterations in global histone modifications, and carcinogenesis.
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Mice heterozygous for CREB binding protein are hypersensitive to ?-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm.
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Microfluidic Mobility Shift Profiling of Lysine Acetyltransferases Enables Screening and Mechanistic Analysis of Cellular Acetylation Inhibitors.
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MicroRNA-224 is up-regulated in hepatocellular carcinoma through epigenetic mechanisms.
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Microtubule Acetylation Controls MDA-MB-231 Breast Cancer Cell Invasion through the Modulation of Endoplasmic Reticulum Stress.
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miR-639 Expression Is Silenced by DNMT3A-Mediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer Cells.
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miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
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MITF Expression Predicts Therapeutic Vulnerability to p300 Inhibition in Human Melanoma.
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Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes.
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Modeling and analysis of the impacts of jet lag on circadian rhythm and its role in tumor growth.
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Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing.
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Modeling the circadian clock: from molecular mechanism to physiological disorders.
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Models of intermittent hypoxia and obstructive sleep apnea: molecular pathways and their contribution to cancer.
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Modulation of circadian rhythm of DNA synthesis in tumor cells by inhibiting platelet-derived growth factor signaling.
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Modulation of p300/CBP Acetylation of Nucleosomes by Bromodomain Ligand I-CBP112.
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Modulatory effects of 5-fluorouracil on the rhythmic expression of circadian clock genes: a possible mechanism of chemotherapy-induced circadian rhythm disturbances.
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Molecular analysis of encapsulated papillary carcinoma of the breast with and without invasion.
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Molecular analysis of the N-acetyltransferase 1 gene (NAT1*) using polymerase chain reaction-restriction fragment-single strand conformation polymorphism assay.
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Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.
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Montelukast inhibits tumour necrosis factor-alpha-mediated interleukin-8 expression through inhibition of nuclear factor-kappaB p65-associated histone acetyltransferase activity.
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Mouse period1 gene expression recording from olfactory bulb under free moving conditions with a portable optic fibre device.
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Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.
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MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease.
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mRNA expression profiling of histone modifying enzymes in pediatric acute monoblastic leukemia.
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Multi-omics analysis of the prognosis and therapeutic significance of circadian clock in ovarian cancer.
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Multiple Machine Learning Based-Chemoinformatics Models for Identification of Histone Acetyl Transferase Inhibitors.
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Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours.
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Mutation and association analyses of the candidate genes ESR1, ESR2, MAX, PCNA, and KAT2A in patients with unexplained MSH2-deficient tumors.
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Mutational dynamics in human tumors confirm the neutral intrinsic instability of the mitochondrial D-loop poly-cytidine repeat.
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Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation.
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Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.
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MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis.
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MYC Ran Up the Clock: The Complex Interplay between MYC and the Molecular Circadian Clock in Cancer.
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MYST family histone acetyltransferases take center stage in stem cells and development.
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MYST1/KAT8 contributes to tumor progression by activating EGFR signaling in glioblastoma cells.
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Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells.
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N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.
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N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer.
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N-acetyltransferase (NAT2) polymorphism and breast cancer susceptibility: a lack of association in a case-control study of Turkish population.
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N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.
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N-acetyltransferase 1 genetic polymorphism influences the risk of prostate cancer development.
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N-acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: risk variability according to tumour site?
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N-acetyltransferase 2 gene polymorphisms are associated with susceptibility to cancer: a meta-analysis.
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N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.
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N-acetyltransferase 2 genetic variants confer the susceptibility to head and neck carcinoma: evidence from 23 case-control studies.
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N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions.
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N-acetyltransferase 2 influences cancer prevalence in hMLH1/hMSH2 mutation carriers.
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N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk.
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N-acetyltransferase activity as a possible criterion in prognosing the anti-tumor effect of cyclophosphamide.
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N-Acetyltransferase phenotypes in the urinary bladder carcinogenesis of a low-risk population.
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N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: a pooled analysis of variations from 59 studies.
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NAT2, XRCC1 and hOGG1 polymorphisms, cigarette smoking, alcohol consumption and risk of upper aerodigestive tract cancer.
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Naturally occurring small molecule compounds that target histone deacetylases and their potential applications in cancer therapy.
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Near-infrared-traceable DNA nano-hydrolase: specific eradication of telomeric G-overhang in vivo.
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NEAT1-TFE3 and KAT6A-TFE3 renal cell carcinomas, new members of MiT family translocation renal cell carcinoma.
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New modification of transurethral incision of the prostate in surgical treatment of bladder outlet obstruction: prospective study.
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New p53 related genes in human tumors: significant downregulation in colon and lung carcinomas.
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New sublines of Chinese hamster CHL stably expressing human NAT1 or NAT2 N-acetyltransferases or Salmonella typhimurium O-acetyltransferase: comparison of the sensitivities to nitroarenes and aromatic amines using the in vitro micronucleus test.
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Nitric oxide-mediated histone hyperacetylation in oral cancer: target for a water-soluble HAT inhibitor, CTK7A.
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No Barrett's-No Cancer: A Proposed New Paradigm for Prevention of Esophageal Adenocarcinoma.
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No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
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Non-Metastatic Cutaneous Melanoma Induces Chronodisruption in Central and Peripheral Circadian Clocks.
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North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies.
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NPAS2 promotes cell survival of hepatocellular carcinoma by transactivating CDC25A.
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Nr1d1, an important circadian pathway regulatory gene, is suppressed by cigarette smoke in murine lungs.
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Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex.
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Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells.
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Nuclear thyroid hormone receptors in C3H/HeN mouse mammary glands and spontaneous tumors.
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Occupational history and genetic N-acetyltransferase polymorphism in urothelial cancer patients of Leverkusen, Germany.
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Ocular surface reconstruction using amniotic membrane following excision of conjunctival and limbal tumors.
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Ocular surface squamous neoplasia: analysis based on the 8th American Joint Committee on Cancer classification.
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Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma.
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Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells.
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Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor.
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Oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) yields PhIP-DNA adducts but not tumors in male Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
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Oscillation of clock and clock controlled genes induced by serum shock in human breast epithelial and breast cancer cells: regulation by melatonin.
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Overexpressed histone acetyltransferase 1 regulates cancer immunity by increasing programmed death-ligand 1 expression in pancreatic cancer.
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Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer.
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Overexpression of the clock gene Per2 suppresses oral squamous cell carcinoma progression by activating autophagy via the PI3K/AKT/mTOR pathway.
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p21 and CK2 interaction-mediated HDAC2 phosphorylation modulates KLF4 acetylation to regulate bladder cancer cell proliferation.
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P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-promoting Myofibroblasts.
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p300 promotes differentiation of Th17 cells via positive regulation of the nuclear transcription factor ROR?t in acute respiratory distress syndrome.
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p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells.
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P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance.
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p33(ING1b) stimulates the transcriptional activity of the estrogen receptor alpha via its activation function (AF) 2 domain.
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p53 recruitment of CREB binding protein mediated through phosphorylated CREB: a novel pathway of tumor suppressor regulation.
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p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300.
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Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1).
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Paeonol promotion of DNA adduct formation and arylamines N-acetyltransferase activity in human colon tumour cells.
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Pan-Cancer Analysis Reveals Disrupted Circadian Clock Associates With T Cell Exhaustion.
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Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma.
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PARP1 facilitates EP300 recruitment to the promoters of the subset of RBL2-dependent genes.
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PCAF inhibits hepatocellular carcinoma metastasis by inhibition of epithelial-mesenchymal transition by targeting Gli-1.
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PCAF-mediated acetylation of ISX recruits BRD4 to promote epithelial-mesenchymal transition.
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PER1 and CLOCK are potential circulating biomarkers for head and neck squamous cell carcinoma.
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PER1 suppresses glycolysis and cell proliferation in oral squamous cell carcinoma via the PER1/RACK1/PI3K signaling complex.
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Per2 Inhibits K562 Leukemia Cell Growth In Vitro and In Vivo Through Cell Cycle Arrest and Apoptosis Induction.
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PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/??catenin signaling pathway.
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Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells.
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Period 3, a tumor suppressor in non-small cell lung cancer, is silenced by hypermethylation.
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Period Family of Clock Genes as Novel Predictors of Survival in Human Cancer: A Systematic Review and Meta-Analysis.
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Period is involved in the proliferation of human pancreatic MIA-PaCa2 cancer cells by TNF-alpha.
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Peritumoural versus subareolar administration of technetium-99m nanocolloid for sentinel lymph node detection in breast cancer: preliminary results of a prospective intra-individual comparative study.
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Perspectives on the Role of Histone Modification in Breast Cancer Progression and the Advanced Technological Tools to Study Epigenetic Determinants of Metastasis.
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Pharmacological inhibition of cryptochrome and REV-ERB promotes DNA repair and cell cycle arrest in cisplatin-treated human cells.
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Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.
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Phospho-?Np63?/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure.
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PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells.
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PIWIL1 suppresses circadian rhythms through GSK3?-induced phosphorylation and degradation of CLOCK and BMAL1 in cancer cells.
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Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae.
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Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
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Polymorphism of N-acetyltransferase 2 Gene and the Susceptibility to Alcoholic Liver Cirrhosis: Interaction With Smoking.
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Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells.
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Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective.
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Potential cancer-related role of circadian gene TIMELESS suggested by expression profiling and in vitro analyses.
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Prevalence of delirium among patients at a cancer ward: Clinical risk factors and prediction by bedside cognitive tests.
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Prognostic and Clinicopathological Significance of X-Box-Binding Protein 1 and N-Acetyltransferase 1 in Gallbladder Cancer.
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Prognostic relevance of Period1 (Per1) and Period2 (Per2) expression in human gastric cancer.
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Prognostic role of upregulated P300 expression in human cancers: A clinical study of synovial sarcoma and a meta-analysis.
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Prognostic Significance of KIF11 and KIF14 Expression in Pancreatic Adenocarcinoma.
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Proliferative Glioblastoma Cancer Cells Exhibit Persisting Temporal Control of Metabolism and Display Differential Temporal Drug Susceptibility in Chemotherapy.
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Prostate expression of N-acetyltransferase 1 (NAT1) and 2 (NAT2) in rapid and slow acetylator congenic Syrian hamster.
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Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation.
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Protein deep sequencing applied to biobank samples from patients with pancreatic cancer.
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Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.
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Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer.
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Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.
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Regulation of estrogen-mediated cell survival and proliferation by p160 coactivators.
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Regulation of genes of the circadian clock in human colon cancer: reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors.
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Regulation of Lef-mediated transcription and p53-dependent pathway by associating beta-catenin with CBP/p300.
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Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1).
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Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300.
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Relationship between lunasin's sequence and its inhibitory activity of histones H3 and H4 acetylation.
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Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.
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Repression of GCN5 expression or activity attenuates c-MYC expression in non-small cell lung cancer.
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Rescue chemotherapy using multidrug chronomodulated hepatic arterial infusion for patients with heavily pretreated metastatic colorectal cancer.
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Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf.
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Review article: a conceptual approach to understanding the molecular mechanisms of cancer development in Barrett's oesophagus.
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Revisiting Histone Deacetylases in Human Tumorigenesis: The Paradigm of Urothelial Bladder Cancer.
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Rewiring of Lactate-Interleukin-1? Autoregulatory Loop with Clock-Bmal1: a Feed-Forward Circuit in Glioma.
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Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells.
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RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.
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RNAi screening identifies KAT8 as a key molecule important for cancer cell survival.
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Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.
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Role of m6A methyltransferase component VIRMA in multiple human cancers (Review).
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Role of Tip60 in Human Melanoma Cell Migration, Metastasis, and Patient Survival.
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Role of ursolic acid chalcone, a synthetic analogue of ursolic acid, in inhibiting the properties of CD133(+) sphere-forming cells in liver stem cells.
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SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells.
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SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.
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Scientific and ethical aspects of genetic screening of workers for cancer risk: the case of the N-acetyltransferase phenotype.
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Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.
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Selective Inhibition of p300 HAT Blocks Cell Cycle Progression, Induces Cellular Senescence, and Inhibits the DNA Damage Response in Melanoma Cells.
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Sex-dependent correlation between survival and expression of genes related to the circadian oscillator in patients with colorectal cancer.
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SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation.
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SIRT1 controls circadian clock circuitry and promotes cell survival: a connection with age-related neoplasms.
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Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates.
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Small Molecules Targeting Biological Clock; A Novel Prospective for Anti-Cancer Drugs.
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Sodium arsenite exposure inhibits histone acetyltransferase p300 for attenuating H3K27ac at enhancers in mouse embryonic fibroblast cells.
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Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes.
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Spatiotemporal chromatin dynamics - A tell tale of circadian epigenetic gene regulation.
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Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.
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SR9009 induces a REV-ERB dependent anti-small-cell lung cancer effect through inhibition of autophagy.
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Stability of d-luciferin for bioluminescence to detect gene expression in freely moving mice for long durations.
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Stabilization of ADAM9 by N-?-acetyltransferase 10 protein contributes to promoting progression of androgen-independent prostate cancer.
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Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation.
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Stress-induced cell-cycle activation in tip60 haploinsufficient adult cardiomyocytes.
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Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization.
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Structure and function of MYST1 histone acetyltransferase in the interactome of animal cells.
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Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain.
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Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor.
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Structure of the p53 transactivation domain in complex with the nuclear coactivator binding domain of CBP.
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Structure of Thermoplasma volcanium Ard1 belongs to N-acetyltransferase family member suggesting multiple ligand binding modes with acetyl coenzyme A and coenzyme A.
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Structure-based identification of drug-like inhibitors of p300 histone acetyltransferase.
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Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.
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Subsequent development of histiocytic sarcoma and follicular lymphoma: cytogenetics and next-generation sequencing analyses provide evidence for transdifferentiation of early common lymphoid precursor-a case report and review of literature.
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Successful implementation of genomically based treatment of chemotherapy refractory peripheral T-cell lymphoma (PTCL).
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SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma.
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Suppression of tumor growth through disruption of hypoxia-inducible transcription.
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Surgical treatment of epibulbar melanocytomas by complete excision and homologous corneoscleral grafting in dogs: 11 cases.
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Synchronous ovarian and endometrial carcinomas in a patient with rubinstein-taybi syndrome: a case report and literature review.
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Talc use, variants of the GSTM1, GSTT1, and NAT2 genes, and risk of epithelial ovarian cancer.
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Targeted next-generation sequencing assays using triplet samples of normal breast tissue, primary breast cancer, and recurrent/metastatic lesions.
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Targeted Proteomic Analyses of Histone H4 Acetylation Changes Associated with Homologous-Recombination-Deficient High-Grade Serous Ovarian Carcinomas.
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Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies.
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Targeting Histone Acetyltransferase MOZ/KAT6A as a New Avenue for Hematological Tumor Therapy.
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Targeting lineage-specific MITF pathway in human melanoma cell lines by A-485, the selective small molecule inhibitor of p300/CBP.
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Targeting NAT10 Induces Apoptosis Associated With Enhancing Endoplasmic Reticulum Stress in Acute Myeloid Leukemia Cells.
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Targeting of Histone Acetyltransferase p300 by Cyclopentenone Prostaglandin ?(12)-PGJ(2) through Covalent Binding to Cys(1438).
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Targeting p300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death due to Abrogation of MYC Expression.
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Tat-interactive Protein-60KDA (TIP60) Regulates the Tumorigenesis of Lung Cancer In Vitro.
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Telomerase activity and telomere lengths in various cell lines: changes of telomerase activity can be another method for chemosensitivity evaluation.
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Temporal regulation of tumor growth in nocturnal mammals: In vivo studies and chemotherapeutical potential.
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TGF-? induces p53/Smads complex formation in the PAI-1 promoter to activate transcription.
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The acetyltransferase p300/CBP-associated factor is a p53 target gene in breast tumor cells.
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The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.
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The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators.
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The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen.
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The cancer driver genes IDH1/2, JARID1C/ KDM5C, and UTX/ KDM6A: crosstalk between histone demethylation and hypoxic reprogramming in cancer metabolism.
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The circadian clock gene Bmal1 acts as a potential anti-oncogene in pancreatic cancer by activating the p53 tumor suppressor pathway.
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The circadian clock gene Per1 suppresses cancer cell proliferation and tumor growth at specific times of day.
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The circadian clock gene PER2 enhances chemotherapeutic efficacy in nasopharyngeal carcinoma when combined with a targeted nanosystem.
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The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma.
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The circadian clock gene period extends healthspan in aging Drosophila melanogaster.
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The circadian clock gene, Bmal1, regulates intestinal stem cell signaling and represses tumor initiation.
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The Circadian Clock in Skin: Implications for Adult Stem Cells, Tissue Regeneration, Cancer, Aging, and Immunity.
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The circadian clock regulates cisplatin-induced toxicity and tumor regression in melanoma mouse and human models.
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The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer.
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The circadian expression of c-MYC is modulated by the histone deacetylase inhibitor trichostatin A in synchronized murine neuroblastoma cells.
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The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells.
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The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments.
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The circadian timing system: a recent addition in the physiological mechanisms underlying pathological and aging processes.
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The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells.
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The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma.
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The CREBBP Acetyltransferase Is a Haploinsufficient Tumor Suppressor in B-cell Lymphoma.
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The diagnosis, management, and role of hematopoietic stem cell transplantation in aggressive peripheral T-cell neoplasms.
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The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases.
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The effect of CTB on P53 protein acetylation and consequence apoptosis on MCF-7 and MRC-5 cell lines.
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The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
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The fission yeast inhibitor of growth (ING) protein PNG1P functions in response to DNA damage.
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The focal treatment of retinoblastoma with emphasis on xenon arc photocoagulation.
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The G1 phase arrest and apoptosis by intrinsic pathway induced by valproic acid inhibit proliferation of BGC-823 gastric carcinoma cells.
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The Genomic Landscape and Pharmacogenomic Interactions of Clock Genes in Cancer Chronotherapy.
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The Histone Acetyltransferase GCN5 Expression Is Elevated and Regulated by c-Myc and E2F1 Transcription Factors in Human Colon Cancer.
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The histone acetyltransferases CBP/p300 are degraded in NIH 3T3 cells by activation of Ras signalling pathway.
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The Histone Variant MacroH2A1 Impacts Circadian Gene Expression and Cell Phenotype in an In Vitro Model of Hepatocellular Carcinoma.
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The Importance of Stochastic Effects for Explaining Entrainment in the Zebrafish Circadian Clock.
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The important tumor suppressor role of PER1 in regulating the cyclin-CDK-CKI network in SCC15 human oral squamous cell carcinoma cells.
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The ING1a Tumor Suppressor Regulates Endocytosis to Induce Cellular Senescence Via the Rb-E2F Pathway.
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The Interplay between Colon Cancer Cells and Tumour-Associated Stromal Cells Impacts the Biological Clock and Enhances Malignant Phenotypes.
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The key roles of the lysine acetyltransferases KAT6A and KAT6B in physiology and pathology.
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The ladder and the clock: cancer pain and public policy at the end of the twentieth century.
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The Mammalian circadian clock gene per2 modulates cell death in response to oxidative stress.
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The Molecular Effects of Sulforaphane and Capsaicin on Metabolism upon Androgen and Tip60 Activation of Androgen Receptor.
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The molecular mechanisms associated with PIN7, a protein-protein interaction network of seven pleiotropic proteins.
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The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target.
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The mutational landscape and prognostic indicators of pseudomyxoma peritonei originating from the ovary.
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The mutational landscape of histiocytic sarcoma associated with lymphoid malignancy.
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The MYST family of histone acetyltransferases and their intimate links to cancer.
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The overexpression of MYST4 in human solid tumors is associated with increased aggressiveness and decreased overall survival.
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The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways.
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The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome.
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The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome.
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The reciprocal interplay between TNF? and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells.
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The role of genetically-based metabolic polymorphisms in human cancer: an ecological study of bladder cancer and N-acetyltransferase in 23 populations.
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The role of the circadian clock in cancer hallmark acquisition and immune-based cancer therapeutics.
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The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies.
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The search for preoperative biomarkers for thyroid carcinoma: application of the thyroid circadian clock properties.
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The Stress Responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating Tip60 and p53.
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The tumor suppressor inhibitor of growth 4 binds double-stranded DNA through its disordered central region.
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The Tumor Suppressor Roles of MYBBP1A, a Major Contributor to Metabolism Plasticity and Stemness.
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The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation.
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The tumor-associated YB-1 protein: new player in the circadian control of cell proliferation.
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The twilight zone between health and sickness: a qualitative exploration with asymptomatic BRCA1 and 2 mutation carriers.
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Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1.
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Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities.
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Time to fight: targeting the circadian clock molecular machinery in cancer therapy.
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Time-Restricted G-Protein Signaling Pathways via GPR176, Gz, and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus.
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TIMELESS Promotes Tumor Progression by Enhancing Macrophages Recruitment in Ovarian Cancer.
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Timing gone awry: distinct tumour suppressive and oncogenic roles of the circadian clock and crosstalk with hypoxia signalling in diverse malignancies.
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Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells.
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Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.
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TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.
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Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response.
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Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation.
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TIP60 K430 SUMOylation attenuates its interaction with DNA-PKcs in S-phase cells: Facilitating homologous recombination and emerging target for cancer therapy.
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Tip60 Protein Isoforms and Altered Function in Skin and Tumors that Overexpress Ornithine Decarboxylase.
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Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-?B pathway.
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TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.
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Tip60-siRNA regulates ABCE1 acetylation to suppress lung cancer growth via activation of the apoptotic signaling pathway.
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TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer.
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Tissue distribution of N-acetyltransferase 1 and 2 catalyzing the N-acetylation of 4-aminobiphenyl and O-acetylation of N-hydroxy-4-aminobiphenyl in the congenic rapid and slow acetylator Syrian hamster.
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Tissue-Specific Dissociation of Diurnal Transcriptome Rhythms During Sleep Restriction in Mice.
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TNF-? induces expression of the circadian clock gene Bmal1 via dual calcium-dependent pathways in rheumatoid synovial cells.
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TNF-? modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells.
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Tobacco habituated and non-habituated subjects exhibit different mutational spectrums in head and neck squamous cell carcinoma.
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Topical mitomycin C for extensive, recurrent conjunctival-corneal squamous cell carcinoma.
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Training the Circadian Clock, Clocking the Drugs, and Drugging the Clock to Prevent, Manage, and Treat Chronic Diseases.
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Transcription factor CCAAT/enhancer-binding protein alpha and critical circadian clock downstream target gene PER2 are highly deregulated in diffuse large B-cell lymphoma.
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Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.
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Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock.
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Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
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TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells.
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Tumor necrosis factor and transforming growth factor ? regulate clock genes by controlling the expression of the cold inducible RNA-binding protein (CIRBP).
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Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and histone deacetylase 4 in human tracheal smooth muscle cells.
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Tumor-targeting pH/redox dual-responsive nanosystem epigenetically reverses cancer drug resistance by co-delivering doxorubicin and GCN5 siRNA.
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Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
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Twist1 Is a TNF-Inducible Inhibitor of Clock Mediated Activation of Period Genes.
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Understanding Histone Deacetylases in the Cancer Development and Treatment: An Epigenetic Perspective of Cancer Chemotherapy.
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Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain.
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Up regulation of NAT10 promotes metastasis of hepatocellular carcinoma cells through epithelial-to-mesenchymal transition.
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Up-regulation of PER3 Expression Is Correlated with Better Clinical Outcome in Acute Leukemia.
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Update on the role of melatonin in the prevention of cancer tumorigenesis and in the management of cancer correlates, such as sleep-wake and mood disturbances: review and remarks.
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Use of Intravitreal Bevacizumab for the Treatment of Secondary Glaucoma Due to Metastatic Iris Tumor.
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Use of the Freund Clock Drawing Test within the Mini-Cog as a screening tool for cognitive impairment in elderly patients with or without cancer.
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Utilization of a Transanal TME Platform to Enable a Distal TME Dissection En Bloc with Presacral Fascia and Pelvic Sidewall with Intraoperative Radiotherapy Delivery in a Locally Advanced Rectal Cancer: Advanced Application of taTME.
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Validation of the Freund Clock Drawing Test as a screening tool to detect cognitive dysfunction in elderly cancer patients undergoing comprehensive geriatric assessment.
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Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells.
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Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
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Vitamin C inhibited DNA adduct formation and arylamine N-acetyltransferase activity and gene expression in rat glial tumor cells.
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Vulvar Squamous Cell Carcinoma: Comprehensive Genomic Profiling of HPV+ Versus HPV- Forms Reveals Distinct Sets of Potentially Actionable Molecular Targets.
Neoplasms
Watching the clock: endoplasmic reticulum-mediated control of circadian rhythms in cancer.
Neoplasms
When the band begins to play: histone acetylation caught in the crossfire of gene control.
Neoplasms
Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.
Neoplasms
Why do cancer cells break from host circadian rhythm? Insights from unicellular organisms.
Neoplasms
[A Case of Anal Canal Adenocarcinoma Locally Controlled by Rectal Amputation after Chemoradiotherapy].
Neoplasms
[Blastomogenic action of low concentrations of nitrosodimethylamine, dimethylamine and nitrogen dioxide]
Neoplasms
[Circadian variation of clock gene Per2 and cancer-related clock-controlled genes in buccal mucosa carcinoma of golden hamster at different cancer stages].
Neoplasms
[Cisplatin sensitivity transcriptional factor and mitochondrial DNA maintenance protein]
Neoplasms
[Determination of the N-acetyltransferase phenotype in urothelial cancer patients and healthy controls]
Neoplasms
[Effect and Regulatory Mechanism of Clock Gene Per1 on Biological Behaviors of Human Oral Squamous Carcinoma Cell].
Neoplasms
[Effect of a chalone-containing preparation from Ehrlich ascites tumor on DNA synthesis and cell division in the tumor in relation to the time of day]
Neoplasms
[Elevated expression of CLOCK is associated with poor prognosis in hepatocellular carcinoma].
Neoplasms
[Genetic and phenotypic polymorphisms in carcinogen-metabolizing enzymes and cancer susceptibility]
Neoplasms
[Glutathione S-transferases (GSTM1, GSTT1 and GSTP1) and N-acetyltransferase 2 polymorphisms and the risk of gastric cancer]
Neoplasms
[hARD1 antiserum preparation and primary immunohistochemical analysis of hARD1 in tumor tissues]
Neoplasms
[Identification of proteins interacting with the circadian clock protein PER1 in tumors using bacterial two-hybrid system technique].
Neoplasms
[Interactions between clock gene mutation, circadian phenotype and tumor growth in mice]
Neoplasms
[Light-induced disruption of the circadian clock and risk of malignant tumors in laboratory animals: state of the problem].
Neoplasms
[Pain relief around the clock is a right of the cancer patient. Coordination of oncological and pharmaceutical methods makes it possible]
Neoplasms
[Patient-controlled analgesia with subcutaneous opoids for out-patients with severe tumour pain.]
Neoplasms
[Production of anti-recombinant human arrest defective 1 protein (hARD1) monoclonal antibodies for assaying human breast cancer tissues]
Neoplasms
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
Neoplasms, Radiation-Induced
Circadian clock, carcinogenesis, chronochemotherapy connections.
Neoplasms, Radiation-Induced
Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer.
Neoplasms, Squamous Cell
Genetic polymorphism of N-acetyltransferase 2 in patients with esophageal cancer.
Neoplasms, Squamous Cell
N-Acetyltransferase 2 polymorphisms, cigarette smoking and alcohol consumption, and oral squamous cell cancer risk.
Neoplasms, Squamous Cell
Real-time PCR analysis of the N-acetyltransferase NAT1 allele *3, *4, *10, *11, *14 and *17 polymorphism in squamous cell cancer of head and neck.
Neoplastic Cells, Circulating
EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.
Nephritis
The role of transcriptional factor D-site-binding protein in circadian CCL2 gene expression in anti-Thy1 nephritis.
Nephrotic Syndrome
A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies.
Nephrotic Syndrome
Urinary sodium excretion in patients with nephrotic syndrome, and its circadian variation.
Nervous System Diseases
At the Intersection of Microbiota and Circadian Clock: Are Sexual Dimorphism and Growth Hormones the Missing Link to Pathology?: Circadian Clock and Microbiota: Potential Egffect on Growth Hormone and Sexual Development.
Nervous System Diseases
Chromatin acetylation status in the manifestation of neurodegenerative diseases: HDAC inhibitors as therapeutic tools.
Nervous System Diseases
Current understanding of the circadian clock and the clinical implications for neurological disorders.
Nervous System Diseases
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Nervous System Diseases
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease.
Nervous System Diseases
Learning Classification Models of Cognitive Conditions from Subtle Behaviors in the Digital Clock Drawing Test.
Nervous System Diseases
Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
Nervous System Diseases
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
Nervous System Diseases
Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.
Nervous System Diseases
Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders.
Nervous System Diseases
The cost of circadian desynchrony: Evidence, insights and open questions.
Nervous System Diseases
Watching the clock and hitting the snooze button: Introduction to the special issue on circadian rhythms and sleep in neurological disorders.
Neuralgia
Curcumin Alleviates Neuropathic Pain by Inhibiting p300/CBP Histone Acetyltransferase Activity-Regulated Expression of BDNF and Cox-2 in a Rat Model.
Neuralgia
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Neuralgia
Epigenetic Augmentation of the Macrophage Inflammatory Protein 2/C-X-C Chemokine Receptor Type 2 Axis through Histone H3 Acetylation in Injured Peripheral Nerves Elicits Neuropathic Pain.
Neuralgia
Epigenetic modification of BDNF mediates neuropathic pain via miR-30a-3p/EP300 axis in CCI rats.
Neuralgia
p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI).
Neurobehavioral Manifestations
A randomised controlled trial testing the impact of exercise on cognitive symptoms and disability of residents with dementia.
Neurobehavioral Manifestations
Gene expression meta-analysis reveals the up-regulation of CREB1 and CREBBP in Brodmann Area 10 of patients with schizophrenia.
Neuroblastoma
A Disruption Mechanism of the Molecular Clock in a MPTP Mouse Model of Parkinson's Disease.
Neuroblastoma
CREB-binding protein is a mediator of neuroblastoma cell death induced by the histone deacetylase inhibitor trichostatin A.
Neuroblastoma
CREB-Binding Protein Regulates Ku70 Acetylation in Response to Ionization Radiation in Neuroblastoma.
Neuroblastoma
Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo.
Neuroblastoma
Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.
Neuroblastoma
Neurogenin 3 recruits CBP co-activator to facilitate histone H3/H4 acetylation in the target gene INSM1.
Neuroblastoma
Ubiquitin ligase TRAF2 attenuates the transcriptional activity of the core clock protein BMAL1 and affects the maximal Per1 mRNA level of the circadian clock in cells.
Neurodegenerative Diseases
"Curcumin, the King of Spices": Epigenetic Regulatory Mechanisms in the Prevention of Cancer, Neurological, and Inflammatory Diseases.
Neurodegenerative Diseases
Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein.
Neurodegenerative Diseases
An acetylated 120-kDa lysosomal transmembrane protein is absent from mucopolysaccharidosis IIIC fibroblasts: a candidate molecule for MPS IIIC.
Neurodegenerative Diseases
ATAXIN-2 activates PERIOD translation to sustain circadian rhythms in Drosophila.
Neurodegenerative Diseases
Brain structural and cognitive correlates of clock drawing performance in Alzheimer's disease.
Neurodegenerative Diseases
Cell clocks and neuronal networks: neuron ticking and synchronization in aging and aging-related neurodegenerative disease.
Neurodegenerative Diseases
Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1.
Neurodegenerative Diseases
Central and peripheral circadian clocks and their role in Alzheimer's disease.
Neurodegenerative Diseases
Chromatin acetylation status in the manifestation of neurodegenerative diseases: HDAC inhibitors as therapeutic tools.
Neurodegenerative Diseases
Circadian clock disruption in neurodegenerative diseases: cause and effect?
Neurodegenerative Diseases
Circadian Clock Genes Are Essential for Normal Adult Neurogenesis, Differentiation, and Fate Determination.
Neurodegenerative Diseases
Circadian clocks and neurodegenerative diseases: time to aggregate?
Neurodegenerative Diseases
Circadian Clocks Function in Concert with Heat Shock Organizing Protein to Modulate Mutant Huntingtin Aggregation and Toxicity.
Neurodegenerative Diseases
Circadian regulation of astrocyte function: implications for Alzheimer's disease.
Neurodegenerative Diseases
Clock Genes, Inflammation and the Immune System-Implications for Diabetes, Obesity and Neurodegenerative Diseases.
Neurodegenerative Diseases
Cognitive Impairment and Dementia: Gaining Insight through Circadian Clock Gene Pathways.
Neurodegenerative Diseases
Disruption of Bmal1 impairs blood-brain barrier integrity via pericyte dysfunction.
Neurodegenerative Diseases
Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Neurodegenerative Diseases
Epigenetic control of learning and memory in Drosophila by Tip60 HAT action.
Neurodegenerative Diseases
Epigenetic Regulation of Axonal Growth of Drosophila Pacemaker Cells by Histone Acetyltransferase Tip60 Controls Sleep.
Neurodegenerative Diseases
Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics.
Neurodegenerative Diseases
Exploring the multifunctional role of melatonin in regulating autophagy and sleep to mitigate Alzheimer's disease neuropathology.
Neurodegenerative Diseases
Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.
Neurodegenerative Diseases
Gene Therapy for Neurodegenerative Diseases: Slowing Down the Ticking Clock.
Neurodegenerative Diseases
Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation.
Neurodegenerative Diseases
Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases.
Neurodegenerative Diseases
Increased p300/CBP expression in acute respiratory distress syndrome is associated with interleukin-17 and prognosis.
Neurodegenerative Diseases
Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.
Neurodegenerative Diseases
Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response.
Neurodegenerative Diseases
Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.
Neurodegenerative Diseases
Neurodegeneration-associated FUS is a novel regulator of circadian gene expression.
Neurodegenerative Diseases
Neurogenetics of Drosophila circadian clock: expect the unexpected.
Neurodegenerative Diseases
Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors.
Neurodegenerative Diseases
PER2 C111G polymorphism, cognitive reserve and cognition in subjective cognitive decline and mild cognitive impairment. A 10-year follow-up study.
Neurodegenerative Diseases
Strong Circadian Rhythms in the Choroid Plexus: Implications for Sleep-Independent Brain Metabolite Clearance.
Neurodegenerative Diseases
The Molecular Clock and Neurodegenerative Disease: A Stressful Time.
Neurodegenerative Diseases
The role of astrocytes in generating circadian rhythmicity in health and disease.
Neurodegenerative Diseases
The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration.
Neurodegenerative Diseases
Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer's Disease Model.
Neurodegenerative Diseases
Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock.
Neurodegenerative Diseases
Variation in the CBP gene involved in epigenetic control associates with cognitive function.
Neurodegenerative Diseases
[Role of circadian rhythms and cellular clock in aging-related diseases].
Neuroendocrine Tumors
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition.
Neurofibromatoses
Coffin-Siris syndrome with café-au-lait spots, obesity and hyperinsulinism caused by a mutation in the ARID1B gene.
Neurofibrosarcoma
Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase.
Neuroinflammatory Diseases
An impaired intrinsic microglial clock system induces neuroinflammatory alterations in the early stage of amyloid precursor protein knock-in mouse brain.
Neuroinflammatory Diseases
Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
Neuroinflammatory Diseases
Gallic acid, a histone acetyltransferase inhibitor, suppresses ?-amyloid neurotoxicity by inhibiting microglial-mediated neuroinflammation.
Neuroinflammatory Diseases
Low-Grade Inflammation Aggravates Rotenone Neurotoxicity and Disrupts Circadian Clock Gene Expression in Rats.
Neuroinflammatory Diseases
Metabolic Profiling of Suprachiasmatic Nucleus Reveals Multifaceted Effects in an Alzheimer's Disease Mouse Model.
Neuroinflammatory Diseases
NAMPT and BMAL1 Are Independently Involved in the Palmitate-Mediated Induction of Neuroinflammation in Hypothalamic Neurons.
Neuroinflammatory Diseases
Sleep disturbance induces depressive behaviors and neuroinflammation by altering the circadian oscillations of clock genes in rats.
Neuroinflammatory Diseases
Suprachiasmatic Nucleus and Subordinate Brain Oscillators: Clock Gene Desynchronization by Neuroinflammation.
Neuroinflammatory Diseases
The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression.
Neuroinflammatory Diseases
The clock-controlled chemokine contributes to neuroinflammation-induced depression.
Neuroinflammatory Diseases
The Effect of Rev-erb? Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia.
Neuroinflammatory Diseases
The Molecular Clock and Neurodegenerative Disease: A Stressful Time.
Neuromuscular Diseases
Complex disease interventions from a network model for type 2 diabetes.
Nevus
Iris Nevus Growth into Melanoma: Analysis of 1611 Consecutive Eyes: The ABCDEF Guide.
Nocturnal Enuresis
The pathophysiology of monosymptomatic nocturnal enuresis with special emphasis on the circadian rhythm of renal physiology.
Non-alcoholic Fatty Liver Disease
3,4-dihydroxytoluene, a metabolite of rutin, suppresses the progression of nonalcoholic fatty liver disease in mice by inhibiting p300 histone acetyltransferase activity.
Non-alcoholic Fatty Liver Disease
Advances in the Involvement of Gut Microbiota in Pathophysiology of NAFLD.
Non-alcoholic Fatty Liver Disease
Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH.
Non-alcoholic Fatty Liver Disease
Black Mulberry Extract Elicits Hepatoprotective Effects in Nonalcoholic Fatty Liver Disease Models by Inhibition of Histone Acetylation.
Non-alcoholic Fatty Liver Disease
Circadian Clock Genes in the Metabolism of Non-alcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Circadian Rhythms in the Pathogenesis and Treatment of Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Diurnal rhythm of follicle-stimulating hormone is associated with nonalcoholic fatty liver disease in a Chinese elderly population.
Non-alcoholic Fatty Liver Disease
Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease: the role of nuclear receptors and circadian rhythmicity.
Non-alcoholic Fatty Liver Disease
Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview.
Non-alcoholic Fatty Liver Disease
Perturbation of the circadian clock and pathogenesis of NAFLD.
Non-alcoholic Fatty Liver Disease
Role of the Circadian Clock in the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease.
Non-alcoholic Fatty Liver Disease
Tannic acid, a novel histone acetyltransferase inhibitor, prevents non-alcoholic fatty liver disease both in vivo and in vitro model.
Non-alcoholic Fatty Liver Disease
The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis.
Non-alcoholic Fatty Liver Disease
The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis.
Non-alcoholic Fatty Liver Disease
XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis.
Non-ST Elevated Myocardial Infarction
Abnormal circadian rhythms are associated with plaque instability in acute coronary syndrome patients.
Obesity
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism.
Obesity
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Obesity
A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.
Obesity
Altered circadian rhythm and metabolic gene profile in rats subjected to advanced light phase shifts.
Obesity
Altered clock gene expression in obese visceral adipose tissue is associated with metabolic syndrome.
Obesity
AMP-activated protein kinase as a key molecular link between metabolism and clockwork.
Obesity
Analysis of Evolution and Ethnic Diversity at Glucose-Associated SNPs of Circadian Clock-Related Loci with Cryptochrome 1, Cryptochrome 2, and Melatonin receptor 1B.
Obesity
Association between genetic variants of the clock gene and obesity and sleep duration.
Obesity
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.
Obesity
Associations between REV-ERB?, sleep duration and body mass index in European adolescents.
Obesity
Associations of metabolic parameters and ethanol consumption with messenger RNA expression of clock genes in healthy men.
Obesity
At the Intersection of Microbiota and Circadian Clock: Are Sexual Dimorphism and Growth Hormones the Missing Link to Pathology?: Circadian Clock and Microbiota: Potential Egffect on Growth Hormone and Sexual Development.
Obesity
Berberine stimulates fibroblast growth factor 21 by modulating the molecular clock component brain and muscle Arnt-like 1 in brown adipose tissue.
Obesity
Bmal1 is required for beta cell compensatory expansion, survival and metabolic adaptation to diet-induced obesity in mice.
Obesity
Brown adipocyte-specific knockout of Bmal1 causes mild but significant thermogenesis impairment in mice.
Obesity
Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats.
Obesity
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation.
Obesity
Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health.
Obesity
Circadian clock dysfunction in human omental fat links obesity to metabolic inflammation.
Obesity
Circadian CLOCK gene polymorphisms in relation to sleep patterns and obesity in African Americans: findings from the Jackson heart study.
Obesity
Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption.
Obesity
Circadian clock genes: Non-circadian roles in sleep, addiction, and psychiatric disorders?
Obesity
Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.
Obesity
Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1.
Obesity
Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of ?-Cell Failure and Diabetes in Male Rats.
Obesity
Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake.
Obesity
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.
Obesity
Circadian rhythms and the gut microbiome synchronize the host's metabolic response to diet.
Obesity
Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte.
Obesity
Circadian rhythms of glucocorticoid hormone actions in target tissues: potential clinical implications.
Obesity
Clinical exome sequencing identifies novel CREBBP variants in 18 Chinese Rubinstein-Taybi Syndrome kids with high frequency of polydactyly.
Obesity
CLOCK 3111T/C genetic variant influences the daily rhythm of autonomic nervous function: relevance to body weight control.
Obesity
CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet.
Obesity
Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs.
Obesity
Clock Genes, Inflammation and the Immune System-Implications for Diabetes, Obesity and Neurodegenerative Diseases.
Obesity
CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids.
Obesity
CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.
Obesity
Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation.
Obesity
Common genetic variation in circadian clock genes are associated with cardiovascular risk factors in an African American and Hispanic/Latino cohort.
Obesity
Common variants of ARID1A and KAT2B are associated with obesity in Indian adolescents.
Obesity
Correlation between inflammatory markers and impaired circadian clock gene expression in type 2 diabetes mellitus.
Obesity
Daily Rhythm of Fractal Cardiac Dynamics Links to Weight Loss Resistance: Interaction with CLOCK 3111T/C Genetic Variant.
Obesity
Diabetes and cardiovascular disease: related disorders created by disturbances in the endogenous clock.
Obesity
Diet-Induced Obesity Alters the Circadian Expression of Clock Genes in Mouse Gustatory Papillae.
Obesity
Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position.
Obesity
Disrupted daily light-dark cycles induce physical inactivity and enhance weight gain in mice depending on dietary fat intake.
Obesity
Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice.
Obesity
Disrupted light-dark cycle induces obesity with hyperglycemia in genetically intact animals.
Obesity
Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals.
Obesity
Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm.
Obesity
Double recording system of Period1 gene expression rhythm in the olfactory bulb and liver in freely moving mouse.
Obesity
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
Obesity
Early nocturnal meal skipping alters the peripheral clock and increases lipogenesis in mice.
Obesity
Effects of circadian restricted feeding on parameters of metabolic syndrome among healthy subjects.
Obesity
Effects of PM Exposure on the Methylation of Clock Genes in a Population of Subjects with Overweight or Obesity.
Obesity
Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity.
Obesity
Evening chronotype associates with obesity in severely obese subjects: interaction with CLOCK 3111T/C.
Obesity
Food for thought: hormonal, experiential, and neural influences on feeding and obesity.
Obesity
Functional CLOCK Is Not Essentially Associated with Metabolic Disruption Caused by Sleep Phase Feeding in Mice.
Obesity
G-protein-coupled receptor signaling through Gpr176, Gz, and RGS16 tunes time in the center of the circadian clock [Review].
Obesity
Gene-by-environment interactions of the CLOCK, PEMT, and GHRELIN loci with average sleep duration in relation to obesity traits using a cohort of 643 New Zealand European children.
Obesity
Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity.
Obesity
Hepatic gene therapy rescues high-fat diet responses in circadian Clock mutant mice.
Obesity
High fat diet induced abnormalities in metabolism, growth, behavior, and circadian clock in Drosophila melanogaster.
Obesity
High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver.
Obesity
High-fat feeding exerts minimal effects on rhythmic mRNA expression of clock genes in mouse peripheral tissues.
Obesity
Hormones and the autonomic nervous system are involved in suprachiasmatic nucleus modulation of glucose homeostasis.
Obesity
Impact of circadian misalignment on energy metabolism during simulated nightshift work.
Obesity
Induction of Core Circadian Clock Transcription Factor Bmal1 Enhances ?-Cell Function and Protects Against Obesity-Induced Glucose Intolerance.
Obesity
Influence of Age on Clock Gene Expression in Peripheral Blood Cells of Healthy Women.
Obesity
Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression.
Obesity
Influence of the core circadian gene "Clock" on obesity and leptin resistance in mice.
Obesity
Intermittent Fasting Does Not Uniformly Impact Genes Involved in Circadian Regulation in Women with Obesity.
Obesity
Intermittent fasting from dawn to sunset for 30 consecutive days is associated with anticancer proteomic signature and upregulates key regulatory proteins of glucose and lipid metabolism, circadian clock, DNA repair, cytoskeleton remodeling, immune system and cognitive function in healthy subjects.
Obesity
Investigation of 3111T/C polymorphism of the CLOCK gene in obese individuals with or without binge eating disorder: Association with higher body mass index.
Obesity
Leptin Normalizes Photic Synchronization in Male ob/ob Mice, via Indirect Effects on the Suprachiasmatic Nucleus.
Obesity
Light rhythm and diet differently influence facets of the metabolic syndrome in WOKW rats.
Obesity
Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring.
Obesity
Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice.
Obesity
Methods for monitoring the functional status of the circadian system in dietary surveys studies: application criteria and interpretation of results.
Obesity
Methylation on the Circadian Gene BMAL1 Is Associated with the Effects of a Weight Loss Intervention on Serum Lipid Levels.
Obesity
Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.
Obesity
miRNA-10a-5p Alleviates Insulin Resistance and Maintains Diurnal Patterns of Triglycerides and Gut Microbiota in High-Fat Diet-Fed Mice.
Obesity
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
Obesity
Mouse period1 gene expression recording from olfactory bulb under free moving conditions with a portable optic fibre device.
Obesity
Myeloid cell-specific disruption of Period1 and Period2 exacerbates diet-induced inflammation and insulin resistance.
Obesity
Nonhomeostatic control of human appetite and physical activity in regulation of energy balance.
Obesity
Nuclear receptors as targets for drug development: molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin.
Obesity
Nutrition, movement and sleep behaviours: their interactions in pathways to obesity and cardiometabolic diseases.
Obesity
Obesity alters the expression profile of clock genes in peripheral blood mononuclear cells.
Obesity
Obesity Disrupts Rhythmic Clock Gene Expression in Maternal Adipose Tissue during Rat Pregnancy.
Obesity
Perinatal nutrient restriction induces long-lasting alterations in the circadian expression pattern of genes regulating food intake and energy metabolism.
Obesity
Period1 gene expression in the olfactory bulb and liver of freely moving streptozotocin-treated diabetic mouse.
Obesity
Peripheral circadian misalignment: contributor to systemic insulin resistance and potential intervention to improve bariatric surgical outcomes.
Obesity
Physical activity and sex modulate obesity risk linked to 3111T/C gene variant of the CLOCK gene in an elderly population: the SUN Project.
Obesity
Polymorphic Appetite Effects on Waist Circumference Depend on rs3749474 CLOCK Gene Variant.
Obesity
Potential Roles of Dec and Bmal1 Genes in Interconnecting Circadian Clock and Energy Metabolism.
Obesity
PPARs, Cardiovascular Metabolism, and Function: Near- or Far-from-Equilibrium Pathways.
Obesity
Preventive effect of L-carnitine on the disorder of lipid metabolism and circadian cClock of mice subjected to chronic jet-lag.
Obesity
Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice.
Obesity
Restoration of circadian corticosterone rhythm in ventromedial hypothalamic lesioned rats.
Obesity
Role of Hypothalamic Creb-Binding Protein in Obesity and Molecular Reprogramming of Metabolic Substrates.
Obesity
Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Obesity
Seasonal differences in clock gene expression levels in buccal epithelial cells of obese men: a pilot study.
Obesity
Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.
Obesity
Serotonin, a possible intermediate between disturbed circadian rhythms and metabolic disease.
Obesity
Sex Differences in the Impact of Shift Work Schedules on Pathological Outcomes in an Animal Model of Ischemic Stroke.
Obesity
SIRT1 and CLOCK 3111T>C combined genotype is associated with evening preference and weight loss resistance in a behavioral therapy treatment for obesity.
Obesity
Sleep and circadian rhythms: key components in the regulation of energy metabolism.
Obesity
Stability of d-luciferin for bioluminescence to detect gene expression in freely moving mice for long durations.
Obesity
Study of the association between 3111T/C polymorphism of the CLOCK gene and the presence of overweight in schoolchildren.
Obesity
Sugar sensor genes in the murine gastrointestinal tract display a cephalocaudal axis of expression and a diurnal rhythm.
Obesity
Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats.
Obesity
Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity.
Obesity
Targeting of the circadian clock via CK1?/? to improve glucose homeostasis in obesity.
Obesity
The circadian clock regulates autophagy directly through the nuclear hormone receptor Nr1d1/Rev-erb? and indirectly via Cebpb/(C/ebp?) in zebrafish.
Obesity
The clock diet: a practical nutritional guide to manage obesity through chrononutrition.
Obesity
The clock gene Rev-erb? regulates pancreatic ?-cell function: modulation by leptin and high-fat diet.
Obesity
The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway.
Obesity
The endogenous circadian clock programs animals to eat at certain times of the 24-hour day: What if we ignore the clock?
Obesity
The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice.
Obesity
The nuclear receptor REV-ERB? is required for the daily balance of carbohydrate and lipid metabolism.
Obesity
The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism.
Obesity
Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock.
Obesity
Time-Restricted G-Protein Signaling Pathways via GPR176, Gz, and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus.
Obesity
Translating around the clock: Multi-level regulation of post-transcriptional processes by the circadian clock.
Obesity
Ursolic Acid Attenuates Hepatic Steatosis, Fibrosis, and Insulin Resistance by Modulating the Circadian Rhythm Pathway in Diet-Induced Obese Mice.
Obesity
Validation of RUNX1 as a potential target for treating circadian clock-induced obesity through preventing migration of group 3 innate lymphoid cells into intestine.
Obesity
Variants in Circadian Rhythm Gene Cry1 Interacts with Healthy Dietary Pattern for Serum Leptin Levels: a Cross-sectional Study.
Obesity
Western diet-induced obesity disrupts the diurnal rhythmicity of hippocampal core clock gene expression in a mouse model.
Obesity
White Adipose Tissue and Circadian Rhythm Dysfunctions in Obesity: Pathogenesis and Available Therapies.
Obesity
[Molecular and genetic aspects of interactions of the circadian clock and the energy-producing substrate metabolism in mammals].
Obesity, Abdominal
Associations of polymorphisms in circadian genes with abdominal obesity in Chinese adult population.
Obesity, Abdominal
Effects of circadian restricted feeding on parameters of metabolic syndrome among healthy subjects.
Obesity, Abdominal
Visceral adiposity and expression of clock genes in peripheral blood mononuclear cells: A pilot study.
Obesity, Maternal
High fat diet and in utero exposure to maternal obesity disrupts circadian rhythm and leads to metabolic programming of liver in rat offspring.
Obesity, Maternal
Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver.
Obesity, Maternal
Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring.
Obesity, Maternal
Obesity Disrupts Rhythmic Clock Gene Expression in Maternal Adipose Tissue during Rat Pregnancy.
Obesity, Maternal
Obesity-induced changes in hepatic and placental clock gene networks in rat pregnancy.
Obesity, Morbid
Oleic acid restores the rhythmicity of the disrupted circadian rhythm found in gastrointestinal explants from patients with morbid obesity.
Optic Nerve Diseases
Comparison of the intraocular pressure-lowering effect of latanoprost and timolol in patients with chronic angle closure glaucoma: a preliminary study.
Optic Nerve Hypoplasia
Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice.
Orthomyxoviridae Infections
Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus.
Osteoarthritis
Altered N-methyl D-aspartate receptor subunit expression causes changes to the circadian clock and cell phenotype in osteoarthritic chondrocytes.
Osteoarthritis
Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NF?B-dependent pathway.
Osteoarthritis
Chronoeffectiveness of indomethacin in four patients suffering from an evolutive osteoarthritis of hip or knee.
Osteoarthritis
Clock gene expression in different synovial cells of patients with rheumatoid arthritis and osteoarthritis.
Osteoarthritis
Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients.
Osteoarthritis
Identification of clock as a mechanosensitive gene by large-scale DNA microarray analysis: downregulation in osteoarthritic cartilage.
Osteoarthritis
IL-1? induces changes in expression of core circadian clock components PER2 and BMAL1 in primary human chondrocytes through the NMDA receptor/CREB and NF-?B signalling pathways.
Osteoarthritis
Melatonin in regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis: involvement of circadian clock genes.
Osteoarthritis
Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway.
Osteoarthritis
Suppression of circadian clock protein cryptochrome 2 promotes osteoarthritis.
Osteoarthritis
The chondrocyte-intrinsic circadian clock is disrupted in human osteoarthritis.
Osteoarthritis
The circadian clock in murine chondrocytes regulates genes controlling key aspects of cartilage homeostasis.
Osteoarthritis
The circadian clock: a central mediator of cartilage maintenance and osteoarthritis development?
Osteoarthritis
Treatment of osteoarthritis pain with controlled release oxycodone or fixed combination oxycodone plus acetaminophen added to nonsteroidal antiinflammatory drugs: a double blind, randomized, multicenter, placebo controlled trial.
Osteoarthritis, Knee
Wnt pathway genes in osteoporosis and osteoarthritis: differential expression and genetic association study.
Osteophyte
What is the tolerated width of periacetabular osteophytes to avoid impingement in cementless THA?: a three-dimensional simulation study.
Osteoporosis
Alpha-synuclein, epigenetics, mitochondria, metabolism, calcium traffic, & circadian dysfunction in Parkinson's disease. An integrated strategy for management.
Osteoporosis
Can Alarming Improve Compliance with Weekly Bisphosphonate in Patients with Osteoporosis?
Osteoporosis
Declining histone acetyltransferase GCN5 represses BMSC-mediated angiogenesis during osteoporosis.
Osteoporosis
Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis.
Osteoporosis
Insights into the Role of Circadian Rhythms in Bone Metabolism: A Promising Intervention Target?
Osteoporosis
Parathyroid hormone resets the cartilage circadian clock of the organ-cultured murine femur.
Osteoporosis
The Role of the Molecular Clock in Skeletal Muscle and What It Is Teaching Us About Muscle-Bone Crosstalk.
Osteosarcoma
A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells.
Osteosarcoma
Circadian clock components ROR? and Bmal1 mediate the anti-proliferative effect of MLN4924 in osteosarcoma cells.
Osteosarcoma
Cry 1 Regulates the Clock Gene Network and Promotes Proliferation and Migration Via the Akt/P53/P21 Pathway in Human Osteosarcoma Cells.
Osteosarcoma
Cryptochrome 2 (CRY2) Suppresses Proliferation and Migration and Regulates Clock Gene Network in Osteosarcoma Cells.
Osteosarcoma
FosB recruits KAT5 to potentiate the growth and metastasis of papillary thyroid cancer in a DPP4-dependent manner.
Osteosarcoma
General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus.
Osteosarcoma
Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation.
Osteosarcoma
Improved tumor control through circadian clock induction by Seliciclib, a cyclin-dependent kinase inhibitor.
Osteosarcoma
MicroRNA-377 exerts a potent suppressive role in osteosarcoma through the involvement of the histone acetyltransferase 1-mediated Wnt axis.
Osteosarcoma
MicroRNA-489 suppresses osteosarcoma invasion, migration and epithelial-to-mesenchymal transition by directly targeting NAA10.
Osteosarcoma
N-?-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas.
Osteosarcoma
Oncogenic and Circadian Effects of Small Molecules Directly and Indirectly Targeting the Core Circadian Clock.
Osteosarcoma
The CtBP1-p300-FOXO3a transcriptional complex represses the expression of the apoptotic regulators Bax and Bim in human osteosarcoma cells.
Osteosarcoma
The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies.
Osteosarcoma
The histone acetyltransferase HBO1 functions as a novel oncogenic gene in osteosarcoma.
Osteosarcoma
Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1.
Ovarian Neoplasms
A potential diagnostic marker for ovarian cancer: Involvement of the histone acetyltransferase, human males absent on the first.
Ovarian Neoplasms
Association between circadian gene CLOCK and cisplatin resistance in ovarian cancer cells: A preliminary study.
Ovarian Neoplasms
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Ovarian Neoplasms
Circadian Gene CLOCK Affects Drug-Resistant Gene Expression and Cell Proliferation in Ovarian Cancer SKOV3/DDP Cell Lines Through Autophagy.
Ovarian Neoplasms
Clinicopathological significance of circadian rhythm-related gene expression levels in patients with epithelial ovarian cancer.
Ovarian Neoplasms
CREBBP knockdown suppressed proliferation and promoted chemo-sensitivity via PERK-mediated unfolded protein response in ovarian cancer.
Ovarian Neoplasms
Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer.
Ovarian Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Ovarian Neoplasms
Ginsenoside Rb1 inhibits hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cells by regulating microRNA-25.
Ovarian Neoplasms
HBO1 directs histone H4 specific acetylation, potentiating mechano-transductionpathways and membrane elasticity in ovarian cancer cells.
Ovarian Neoplasms
KAT6A, a novel regulator of ?-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1.
Ovarian Neoplasms
Multi-omics analysis of the prognosis and therapeutic significance of circadian clock in ovarian cancer.
Ovarian Neoplasms
No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Ovarian Neoplasms
The circadian rhythm and core gene Period2 regulate the chemotherapy effect and multidrug resistance of ovarian cancer through the PI3K signaling pathway.
Ovarian Neoplasms
The overexpression of MYST4 in human solid tumors is associated with increased aggressiveness and decreased overall survival.
Overnutrition
Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes.
Overweight
A variant of the CLOCK gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.
Overweight
CLOCK gene polymorphisms and quality of aging in a cohort of nonagenarians - The MUGELLO Study.
Overweight
CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.
Overweight
Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position.
Overweight
Early dinner or "dinner like a pauper": Evidence, the habitual time of the largest meal of the day - dinner - is predisposing to severe COVID-19 outcome - death.
Overweight
Effects of PM Exposure on the Methylation of Clock Genes in a Population of Subjects with Overweight or Obesity.
Overweight
Genetic variants in human CLOCK associate with total energy intake and cytokine sleep factors in overweight subjects (GOLDN population).
Overweight
Study of the association between 3111T/C polymorphism of the CLOCK gene and the presence of overweight in schoolchildren.
Overweight
Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression.
Overweight
Visceral adiposity and expression of clock genes in peripheral blood mononuclear cells: A pilot study.
Pancreatic Diseases
Protein deep sequencing applied to biobank samples from patients with pancreatic cancer.
Pancreatic Neoplasms
Association between N-acetyltransferase 2 polymorphisms and pancreatic cancer risk: a meta-analysis.
Pancreatic Neoplasms
Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin.
Pancreatic Neoplasms
Deciphering microRNA targets in pancreatic cancer using miRComb R package.
Pancreatic Neoplasms
Defining the molecular pathology of pancreatic body and tail adenocarcinoma.
Pancreatic Neoplasms
FBP1 binds to the bromodomain of BRD4 to inhibit pancreatic cancer progression.
Pancreatic Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Pancreatic Neoplasms
Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors.
Pancreatic Neoplasms
Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer.
Pancreatic Neoplasms
Molecular overlap of fly circadian rhythms and human pancreatic cancer.
Pancreatic Neoplasms
No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer.
Pancreatic Neoplasms
Overexpressed histone acetyltransferase 1 regulates cancer immunity by increasing programmed death-ligand 1 expression in pancreatic cancer.
Pancreatic Neoplasms
P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer.
Pancreatic Neoplasms
Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer.
Pancreatic Neoplasms
Protein deep sequencing applied to biobank samples from patients with pancreatic cancer.
Pancreatic Neoplasms
Research progress on circadian clock genes in common abdominal malignant tumors.
Pancreatic Neoplasms
The association between N-acetyltransferase 2 gene polymorphisms and pancreatic cancer.
Pancreatic Neoplasms
The circadian clock gene Bmal1 acts as a potential anti-oncogene in pancreatic cancer by activating the p53 tumor suppressor pathway.
Pancreatic Neoplasms
The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.
Pancreatic Neoplasms
Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression.
Pancreatitis
PENTOXIFYLLINE PREVENTS LOSS OF PP2A PHOSPHATASE ACTIVITY AND RECRUITMENT OF HISTONE ACETYLTRANSFERASES TO PRO-INFLAMMATORY GENES IN ACUTE PANCREATITIS.
Pancreatitis
Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients.
Papilledema
Optical Coherence Tomography as an Adjunctive Tool for Diagnosing Papilledema in Young Patients.
Papilledema
Variability Within Optic Nerve Optical Coherence Tomography Measurements Distinguishes Papilledema From Pseudopapilledema.
Papilloma
A Protein Array Screen for KSHV LANA Interactors Links LANA to TIP60, PP2A activity and Telomere Shortening.
Papillomavirus Infections
Regulation of the Human Papillomavirus Life Cycle by DNA Damage Repair Pathways and Epigenetic Factors.
Paralysis
A study of five candidate genes in Parkinson's disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism.
Paraplegia
A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform.
Parasitic Diseases
The circadian clock in immune cells controls the magnitude of Leishmania parasite infection.
Parkinson Disease
A Disruption Mechanism of the Molecular Clock in a MPTP Mouse Model of Parkinson's Disease.
Parkinson Disease
A new approach for the quantitative evaluation of the clock drawing test: preliminary results on subjects with Parkinson's disease.
Parkinson Disease
A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson's Disease.
Parkinson Disease
Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease.
Parkinson Disease
Association of slow acetylator genotype of N-acetyltransferase 2 with Parkinson's disease in south Indian population.
Parkinson Disease
Can clock drawing differentiate Alzheimer's disease from other dementias?
Parkinson Disease
Case-control study of debrisoquine 4-hydroxylase, N-acetyltransferase 2, and apolipoprotein E gene polymorphisms in Parkinson's disease.
Parkinson Disease
Circadian influences on dopamine circuits of the brain: regulation of striatal rhythms of clock gene expression and implications for psychopathology and disease.
Parkinson Disease
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back.
Parkinson Disease
CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson's Disease.
Parkinson Disease
Clock drawing errors in dementia: neuropsychological and neuroanatomical considerations.
Parkinson Disease
Clock drawing test: is it useful for dementia screening in patients having Parkinson disease with and without depression?
Parkinson Disease
CLOCK rs1801260 Polymorphism is Associated with Susceptibility to Parkinson's Disease in a Chinese Population.
Parkinson Disease
Clock Test Deficits Related to the Global Cognitive State in Alzheimer's and Parkinson's Disease.
Parkinson Disease
Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin.
Parkinson Disease
Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration.
Parkinson Disease
Detailed genotyping demonstrates association between the slow acetylator genotype for N-acetyltransferase 2 (NAT2) and familial Parkinson's disease.
Parkinson Disease
Deubiquitinase USP29 Governs MYBBP1A in the Brains of Parkinson's Disease Patients.
Parkinson Disease
Discrimination of dementia with lewy bodies from Alzheimer disease and Parkinson disease using the clock drawing test.
Parkinson Disease
Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson's Disease.
Parkinson Disease
Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases.
Parkinson Disease
Does the Clock Tick Slower or Faster in Parkinson's Disease? - Insights Gained From the Synchronized Tapping Task.
Parkinson Disease
Effect of melatonin administration on the PER1 and BMAL1 clock genes in patients with Parkinson's disease.
Parkinson Disease
Effects of histone acetyltransferase inhibitors on L-DOPA-induced dyskinesia in a murine model of Parkinson's disease.
Parkinson Disease
Effects of internal clock and memory disorders on duration reproductions and duration productions in patients with Parkinson's disease.
Parkinson Disease
Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson's disease models.
Parkinson Disease
Expression of clock genes Per1 and Bmal1 in total leukocytes in health and Parkinson's disease.
Parkinson Disease
Freezing of gait and executive functions in patients with Parkinson's disease.
Parkinson Disease
Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
Parkinson Disease
Integration of motor imagery and physical practice in group treatment applied to subjects with Parkinson's disease.
Parkinson Disease
Learning Classification Models of Cognitive Conditions from Subtle Behaviors in the Digital Clock Drawing Test.
Parkinson Disease
Modeling prior information of common genetic variants improves gene discovery for neuroticism.
Parkinson Disease
Motor and cognitive function in Lewy body dementia: comparison with Alzheimer's and Parkinson's diseases.
Parkinson Disease
Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer.
Parkinson Disease
N-acetyltransferase 2 polymorphism in sporadic Parkinson's disease in a Polish population.
Parkinson Disease
Parkinson's Disease Cognitive Phenotypes Show Unique Clock Drawing Features when Measured with Digital Technology.
Parkinson Disease
Parkinson's disease patients showed delayed awareness of motor intention.
Parkinson Disease
Performance at the clock drawing test of individuals affected by Parkinson's disease and healthy subjects: a retrospective study.
Parkinson Disease
Physiotherapy versus physiotherapy plus cognitive training on cognition and quality of life in Parkinson´s disease: randomized clinical trial.
Parkinson Disease
Polymorphisms of catechol-0-methyltransferase (COMT), monoamine oxidase B (MAOB), N-acetyltransferase 2 (NAT2) and cytochrome P450 2D6 (CYP2D6) gene in patients with early onset of Parkinson's disease.
Parkinson Disease
Promoter methylation analysis of seven clock genes in Parkinson's disease.
Parkinson Disease
Psychometric properties of clock and pelvic drawings in Parkinson's disease: A validity and cross-sectional study.
Parkinson Disease
Pyrosequencing analysis of methylation levels of clock genes in leukocytes from Parkinson's disease patients.
Parkinson Disease
Quantitative digital clock drawing test as a sensitive tool to detect subtle cognitive impairments in early stage Parkinson's disease.
Parkinson Disease
Reliability, validity, and diagnostic accuracy of Parkinson's Disease-Cognitive Rating Scale in Iranian patients with idiopathic Parkinson's disease.
Parkinson Disease
Reversal of visuospatial deficit on the Clock Drawing Test in Parkinson's disease by treatment with weak electromagnetic fields.
Parkinson Disease
Slow N-acetyltransferase 2 status leads to enhanced intrastriatal dopamine depletion in 6-hydroxydopamine-lesioned rats.
Parkinson Disease
The Development of the Social Functioning Scale for Patients with Parkinson's Disease.
Parkinson Disease
The interlocking finger test in patients with Parkinson's disease and healthy subjects.
Parkinson Disease
The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia.
Parkinson Disease
Toxins, genetics, and Parkinson's disease: the role of N-acetyltransferase 2.
Parkinson Disease
Treatment of Neurodegeneration: Integrating Photobiomodulation and Neurofeedback in Alzheimer's Dementia and Parkinson's: A Review.
Parkinson Disease
Turning Back the Clock in Parkinson's Disease: Practical Recommendations for Managing Diurnal Symptom Worsening.
Parkinson Disease
[Memantine (akatinol) therapy of cognitive impairment in Parkinson's disease complicated by dementia]
Parkinson Disease
[Role of gene polymorphism of catechol-O-methyltransferase (COMT), monoamine oxidase B (MAOB), cytochrome P450 2D6 (CYP2D6) and N-acetyltransferase 2 (NAT2) in pathogenesis of Parkinson's disease]
Parkinson Disease
[The role of N-acetyltransferase polymorphism in the pathogenesis of Parkinson's disease]
Pediatric Obesity
Disruption of the circadian rhythms and its relationship with pediatric obesity.
Pediatric Obesity
Sex modifies the association between the CLOCK variant rs1801260 and BMI in school-age children.
Perceptual Disorders
Around the clock surveillance: simple graphic disturbance in patients with hemispatial neglect carries implications for the clock drawing task.
Periapical Granuloma
Quantitative Analysis of CCL5 and ep300 in Periapical Inflammatory Lesions.
Periodontal Diseases
Association between bone loss in periodontal disease and polymorphism of N-acetyltransferase (NAT2).
Periodontal Diseases
Polymorphism of the N-acetyltransferase (NAT2), smoking and the potential risk of periodontal disease.
Periodontitis
[K (lysine) acetyltransferase 2A affects the osteogenic differentiation of periodontal ligament stem cells through the canonical Wnt pathway].
Peripheral Arterial Disease
Acetylation phenotype and cytochrome P450IA2 phenotype are unlikely to be associated with peripheral arterial disease.
Peripheral Arterial Disease
Poorer clock draw test scores are associated with greater functional impairment in peripheral artery disease: the Walking and Leg Circulation Study II.
Peripheral Nerve Injuries
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Peritonitis
Circadian Control of Inflammasome Pathways: Implications for Circadian Medicine.
Pheochromocytoma
Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock.
Photophobia
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Photophobia
Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock in Drosophila melanogaster.
Photophobia
Development of the Astyanax mexicanus circadian clock and non-visual light responses.
Photophobia
Development of the light sensitivity of the clock genes Period1 and Period2, and immediate-early gene c-fos within the rat suprachiasmatic nucleus.
Photophobia
Development of the Molecular Circadian Clock and Its Light Sensitivity in Drosophila Melanogaster.
Photophobia
Disruption of Cryptochrome partially restores circadian rhythmicity to the arrhythmic period mutant of Drosophila.
Photophobia
Effects of vitamin B12 on plasma melatonin rhythm in humans: increased light sensitivity phase-advances the circadian clock?
Photophobia
Evolution shapes the responsiveness of the D-box enhancer element to light and reactive oxygen species in vertebrates.
Photophobia
Expression and light sensitivity of clock genes Per1 and Per2 and immediate-early gene c-fos within the retina of early postnatal Wistar rats.
Photophobia
Human Melatonin and Alerting Response to Blue-Enriched Light Depend on a Polymorphism in the Clock Gene PER3.
Photophobia
Importance of magnesium depletion with hypofunction of the biological clock in the pathophysiology of headhaches with photophobia, sudden infant death and some clinical forms of multiple sclerosis.
Photophobia
Individual differences in light sensitivity affect sleep and circadian rhythms.
Photophobia
JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS.
Photophobia
Novel features of cryptochrome-mediated photoreception in the brain circadian clock of Drosophila.
Photophobia
Reduced light sensitivity of the circadian clock in a hypopigmented mouse mutant.
Photophobia
The ability to entrain to long photoperiods differs between 3 Drosophila melanogaster wild-type strains and is modified by twilight simulation.
Photophobia
The Compound Eye Possesses a Self-Sustaining Circadian Oscillator in the Cricket Gryllus bimaculatus.
Photophobia
The effect of neuropeptides from Limulus on its circadian rhythm in retinal sensitivity.
Photophobia
The Role of Light Sensitivity and Intrinsic Circadian Period in Predicting Individual Circadian Timing.
Photophobia
White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter.
Photophobia
Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity.
Pituitary ACTH Hypersecretion
MECHANISMS IN ENDOCRINOLOGY: A sense of time of the glucocorticoid circadian clock: from the ontogeny to the diagnosis of Cushing's syndrome.
Pituitary ACTH Hypersecretion
Peripheral clock system circadian abnormalities in Cushing's disease.
Pituitary Neoplasms
Anacardic acid induces caspase-independent apoptosis and radiosensitizes pituitary adenoma cells.
Pituitary Neoplasms
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition.
Pituitary Neoplasms
Histone acetyltransferase p300 regulates the expression of human pituitary tumor transforming gene (hPTTG).
Pneumococcal Infections
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Pneumonia
Abnormal histone acetylase and deacetylase expression and function in lung inflammation.
Pneumonia
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action.
Pneumonia
Circadian clock component REV-ERB? controls homeostatic regulation of pulmonary inflammation.
Pneumonia
Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway.
Pneumonia
Circadian variation in pulmonary inflammatory responses is independent of rhythmic glucocorticoid signaling in airway epithelial cells.
Pneumonia
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Pneumonia
Molecular clock REV-ERB? regulates cigarette smoke-induced pulmonary inflammation and epithelial-mesenchymal transition.
Pneumonia
Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation.
Pneumonia
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Pneumonia
The nuclear receptor and clock gene REV-ERB? regulates cigarette smoke-induced lung inflammation.
Pneumonia, Pneumococcal
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia.
Pneumonia, Pneumocystis
Pneumocystis jirovecii Rtt109, a novel drug target for Pneumocystis pneumonia in immunosuppressed humans.
Polycystic Ovary Syndrome
Altered circadian clock as a novel therapeutic target for constant darkness-induced insulin resistance and hyperandrogenism of polycystic ovary syndrome.
Polycystic Ovary Syndrome
Circadian Clock Genes REV-ERBs Inhibits Granulosa Cells Apoptosis by Regulating Mitochondrial Biogenesis and Autophagy in Polycystic Ovary Syndrome.
Polycystic Ovary Syndrome
Circadian Rhythms Within the Female HPG Axis: From Physiology to Etiology.
Polydactyly
Clinical exome sequencing identifies novel CREBBP variants in 18 Chinese Rubinstein-Taybi Syndrome kids with high frequency of polydactyly.
Polyendocrinopathies, Autoimmune
Aire downregulates multiple molecules that have contradicting immune-enhancing and immune-suppressive functions.
Polyuria
Suprachiasmatic nucleus in a patient with multiple system atrophy with abnormal circadian rhythm of arginine-vasopressin secretion into plasma.
Polyuria
The Clock mutant mouse is a novel experimental model for nocturia and nocturnal polyuria.
Polyuria
The pathophysiology of monosymptomatic nocturnal enuresis with special emphasis on the circadian rhythm of renal physiology.
Porcine Reproductive and Respiratory Syndrome
A G-Box-Like Motif Is Necessary for Transcriptional Regulation by Circadian Pseudo-Response Regulators in Arabidopsis.
Porcine Reproductive and Respiratory Syndrome
A molecular clock dates the common ancestor of European-type porcine reproductive and respiratory syndrome virus at more than 10 years before the emergence of disease.
Porcine Reproductive and Respiratory Syndrome
BBX19 fine-tunes the circadian rhythm by interacting with PSEUDO-RESPONSE REGULATOR proteins to facilitate their repressive effect on morning-phased clock genes.
Porcine Reproductive and Respiratory Syndrome
Degradation of CREB-binding protein and modulation of type I interferon induction by the zinc finger motif of the porcine reproductive and respiratory syndrome virus nsp1? subunit.
Porcine Reproductive and Respiratory Syndrome
Modulation of type I interferon induction by porcine reproductive and respiratory syndrome virus and degradation of CREB-binding protein by non-structural protein 1 in MARC-145 and HeLa cells.
Porcine Reproductive and Respiratory Syndrome
Pseudo-Response Regulators (PRRs) or True Oscillator Components (TOCs).
Porcine Reproductive and Respiratory Syndrome
Roles of Circadian Clock in Developmental Controls and Stress Responses in Arabidopsis: Exploring a Link for Three Components of Clock Function in Arabidopsis
Porphyrias
Relationship between N-acetyltransferase (NAT) activity and liver protoporphyrin level in experimental porphyria.
Prader-Willi Syndrome
Clinical exome sequencing identifies novel CREBBP variants in 18 Chinese Rubinstein-Taybi Syndrome kids with high frequency of polydactyly.
Prader-Willi Syndrome
Malignant fibrous histiocytoma-pleomorphic sarcoma, NOS gene expression, histology, and clinical course. A pilot study.
Pre-Eclampsia
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies.
Pre-Eclampsia
Circadian clock gene Clock is involved in the pathogenesis of preeclampsia through hypoxia.
Pre-Eclampsia
Early- and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues.
Pre-Eclampsia
Effective Aspirin Treatment of Women at Risk for Preeclampsia Delays the Metabolic Clock of Gestation.
Pre-Eclampsia
Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Beating the Clock in T-cell Acute Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
CREBBP HAT domain mutations prevail in relapse cases of high hyperdiploid childhood acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
CREBBP knockdown enhances RAS/RAF/MEK/ERK signaling in Ras pathway mutated acute lymphoblastic leukemia but does not modulate chemotherapeutic response.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Detection of a Cryptic EP300/ZNF384 Gene Fusion by Chromosomal Microarray and Next-Generation Sequencing Studies in a Pediatric Patient with B-Lymphoblastic Leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Exploration of Coding and Non-coding Variants in Cancer Using GenomePaint.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
MSH2 deletion with CREBBP and KRAS mutations in pediatric high-hyperdiploid acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Multilocus association of genetic variants in MLL, CREBBP, EP300, and TOP2A with childhood acute lymphoblastic leukemia in Hispanics from Texas.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
N-Acetyltransferase 2 (NAT2) polymorphism as a risk modifier of susceptibility to pediatric acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Symplekin, a polyadenylation factor, prevents MOZ and MLL activity on HOXA9 in hematopoietic cells.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
The Leukemia-Driving Fusion Protein TCF3-HLF Is Regulated by EP300.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.
Prediabetic State
Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes.
Prediabetic State
Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content.
Prediabetic State
Prediabetes and Type 2 Diabetes Are Associated With Generalized Microvascular Dysfunction: The Maastricht Study.
Prediabetic State
[Early consequent blood pressure lowering is the goal. The "blood vessel clock ticks" in prediabetic state]
Pregnancy Complications
Placental epigenetic clocks: estimating gestational age using placental DNA methylation levels.
Premature Birth
Early- and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues.
Premature Birth
Low CLOCK and CRY2 in 2nd trimester human maternal blood and risk of preterm birth: A nested case-control study.
Premature Birth
Revisiting the placental clock: Early corticotrophin-releasing hormone rise in recurrent preterm birth.
Premature Birth
The Association of Polymorphisms in Circadian Clock and Lipid Metabolism Genes With 2nd Trimester Lipid Levels and Preterm Birth.
Primary Myelofibrosis
More on Myb in myelofibrosis: molecular analyses of MYB and EP300 in 55 patients with myeloproliferative disorders.
Progeria
Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies.
Progeria
Epigenetic clocks galore: a new improved clock predicts age-acceleration in Hutchinson Gilford Progeria Syndrome patients.
Prolactinoma
A review of dopamine agonist therapy in type 2 diabetes and effects on cardio-metabolic parameters.
Prostatic Hyperplasia
Kinetics of acetyl coenzyme A: arylamine N-acetyltransferase from rapid and slow acetylator human benign prostatic hyperplasia tissues.
Prostatic Neoplasms
A differential expression network method identifies ankylosing spondylitis-related genes.
Prostatic Neoplasms
A quantitative study on the in vitro and in vivo acetylation of high mobility group A1 proteins.
Prostatic Neoplasms
Abiraterone Acetate Induces CREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in Prostate Cancer Cells.
Prostatic Neoplasms
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer.
Prostatic Neoplasms
Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells.
Prostatic Neoplasms
All-trans-retinoic acid modulation of drug-metabolizing enzyme activities: investigation with selective metabolic drug probes.
Prostatic Neoplasms
Androgen receptor signalling in prostate cancer: the functional consequences of acetylation.
Prostatic Neoplasms
Association of prostate cancer with rapid N-acetyltransferase 1 (NAT1*10) in combination with slow N-acetyltransferase 2 acetylator genotypes in a pilot case-control study.
Prostatic Neoplasms
Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer.
Prostatic Neoplasms
Circadian Disruption and Prostate Cancer Risk: An Updated Review of Epidemiological Evidences.
Prostatic Neoplasms
Circadian genes and risk of prostate cancer: Findings from the EPICAP study.
Prostatic Neoplasms
CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease.
Prostatic Neoplasms
Coactivator MYST1 Regulates NF-?B and AR Functions during Proliferation of Prostate Cancer Cells.
Prostatic Neoplasms
DNA methylation-based chromatin compartments and ChIP-seq profiles reveal transcriptional drivers of prostate carcinogenesis.
Prostatic Neoplasms
Expression and function of androgen receptor coactivators in prostate cancer.
Prostatic Neoplasms
Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development.
Prostatic Neoplasms
Extrahepatic expression of the N-acetylation polymorphism toward arylamine carcinogens in tumor target organs of an inbred rat model.
Prostatic Neoplasms
Genetic polymorphism of the N-acetyltransferase 2 gene, and susceptibility to prostate cancer: a pilot study in north Indian population.
Prostatic Neoplasms
Genetic variation of clock genes and cancer risk: a field synopsis and meta-analysis.
Prostatic Neoplasms
High copy number variations, particular transcription factors, and low immunity contribute to the stemness of prostate cancer cells.
Prostatic Neoplasms
In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation.
Prostatic Neoplasms
ING3 promotes prostate cancer growth by activating the androgen receptor.
Prostatic Neoplasms
Isoform-Specific Lysine Methylation of ROR?2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression.
Prostatic Neoplasms
KAT2A-mediated AR translocation into nucleus promotes abiraterone-resistance in castration-resistant prostate cancer.
Prostatic Neoplasms
KAT5 and KAT6B are in positive regulation on cell proliferation of prostate cancer through PI3K-AKT signaling.
Prostatic Neoplasms
Lack of Association of the N-acetyltransferase NAT1*10 Allele with Prostate Cancer Incidence, Grade, or Stage Among Smokers in Finland.
Prostatic Neoplasms
Make the right measurement: Discovery of an allosteric inhibition site for p300-HAT.
Prostatic Neoplasms
Mechanisms of endocrine therapy-responsive and -unresponsive prostate tumours.
Prostatic Neoplasms
Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells.
Prostatic Neoplasms
Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer.
Prostatic Neoplasms
miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells.
Prostatic Neoplasms
Moving Beyond the Androgen Receptor (AR): Targeting AR-Interacting Proteins to Treat Prostate Cancer.
Prostatic Neoplasms
MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.
Prostatic Neoplasms
MYC-Mediated Ribosomal Gene Expression Sensitizes Enzalutamide-resistant Prostate Cancer Cells to EP300/CREBBP Inhibitors.
Prostatic Neoplasms
N-acetyltransferase 1 genetic polymorphism influences the risk of prostate cancer development.
Prostatic Neoplasms
N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.
Prostatic Neoplasms
No association between variant N-acetyltransferase genes, cigarette smoking and Prostate Cancer susceptibility among men of African descent.
Prostatic Neoplasms
p300 Acetyltransferase Regulates Androgen Receptor Degradation and PTEN-Deficient Prostate Tumorigenesis.
Prostatic Neoplasms
p300 is up-regulated by docetaxel and is a target in chemoresistant prostate cancer.
Prostatic Neoplasms
p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6.
Prostatic Neoplasms
p300/CBP-associated factor promotes autophagic degradation of ?-catenin through acetylation and decreases prostate cancer tumorigenicity.
Prostatic Neoplasms
p73gamma transactivates the p21 promoter through preferential interaction with the p300/CBP-associated factor in human prostate cancer cells.
Prostatic Neoplasms
Polymorphisms in NAT2, CYP2D6, CYP2C19 and GSTP1 and their association with prostate cancer.
Prostatic Neoplasms
Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor.
Prostatic Neoplasms
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse.
Prostatic Neoplasms
Role of 11C-choline positron emission tomography in prostate cancer recurrence--potential for delayed cure or just resetting the clock of the disease?
Prostatic Neoplasms
Social Jetlag and Prostate Cancer Incidence in Alberta's Tomorrow Project: A Prospective Cohort Study.
Prostatic Neoplasms
Testing the circadian gene hypothesis in prostate cancer: a population-based case-control study.
Prostatic Neoplasms
The Molecular Effects of Sulforaphane and Capsaicin on Metabolism upon Androgen and Tip60 Activation of Androgen Receptor.
Prostatic Neoplasms
Therapeutic targeting of the CBP/p300 bromodomain blocks the growth of castration-resistant prostate cancer.
Prostatic Neoplasms
Tip60 is associated with resistance to X-ray irradiation in prostate cancer.
Prostatic Neoplasms
Tip60 promotes prostate cancer cell proliferation by translocation of androgen receptor into the nucleus.
Prostatic Neoplasms
TNF-? regulates diabetic macrophage function through the histone acetyltransferase MOF.
Prostatic Neoplasms
Variation in N-acetyltransferase 2 (NAT2), smoking and risk of prostate cancer in the Slovak population.
Prostatic Neoplasms
Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer.
Prostatic Neoplasms
[hARD1 antiserum preparation and primary immunohistochemical analysis of hARD1 in tumor tissues]
Prostatitis
Preoperative risk factors of postoperative delirium after transurethral prostatectomy for benign prostatic hyperplasia.
Protein Deficiency
Protein malnutrition after weaning disrupts peripheral clock and daily insulin secretion in mice.
Proteinuria
Circadian glomerular function: from physiology to molecular and therapeutical aspects.
Proteinuria
Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants.
Proteinuria
The association between shift work and chronic kidney disease in manual labor workers using data from the Korea National Health and Nutrition Examination Survey (KNHANES 2011-2014).
Pseudorabies
Pseudorabies virus glycoprotein gE suppresses interferon-? production via CREB-binding protein degradation.
Psittacosis
Comparative Analysis of Chlamydia psittaci Genomes Reveals the Recent Emergence of a Pathogenic Lineage with a Broad Host Range.
Psoriasis
Combined analysis of polymorphisms of the tumor necrosis factor-alpha and interleukin-10 promoter regions and polymorphic xenobiotic metabolizing enzymes in psoriasis.
Psoriasis
The Circadian Clock in Skin: Implications for Adult Stem Cells, Tissue Regeneration, Cancer, Aging, and Immunity.
Psoriasis
The Impact of Ramadan Fasting on the Reduction of PASI Score, in Moderate-To-Severe Psoriatic Patients: A Real-Life Multicenter Study.
Psoriasis
[Molecular Mechanism of KLF4 Up-regulating Keratin 17 Expression in Keratinocytes].
Psychogenic Nonepileptic Seizures
Seizures by the clock: Temporal patterns of psychogenic nonepileptic seizures.
Psychomotor Agitation
Variation in candidate genes CLOCK and ADCYAP1 does not consistently predict differences in migratory behavior in the songbird genus Junco.
Pulmonary Disease, Chronic Obstructive
A 6-alkylsalicylate histone acetyltransferase inhibitor inhibits histone acetylation and pro-inflammatory gene expression in murine precision-cut lung slices.
Pulmonary Disease, Chronic Obstructive
CBX4 Provides an Alternate Mode of Colon Cancer Development via Potential Influences on Circadian Rhythm and Immune Infiltration.
Pulmonary Disease, Chronic Obstructive
Cognitive dysfunction in severe chronic obstructive pulmonary disease (COPD) with or without Long-Term Oxygen Therapy (LTOT).
Pulmonary Disease, Chronic Obstructive
Decreased histone deacetylase activity in chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Disruption of SIRT1-mediated Control of Circadian Molecular Clock and Inflammation in Chronic Obstructive Pulmonary Disease.
Pulmonary Disease, Chronic Obstructive
Do epigenetic events take place in the vastus lateralis of patients with mild chronic obstructive pulmonary disease?
Pulmonary Disease, Chronic Obstructive
Epigenetic mechanisms in respiratory muscle dysfunction of patients with chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Expression of CREB-binding protein and peroxisome proliferator-activated receptor gamma during formoterol or formoterol and corticosteroid therapy of chronic obstructive pulmonary disease.
Pulmonary Disease, Chronic Obstructive
Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD.
Pulmonary Disease, Chronic Obstructive
Quadriceps muscle weakness and atrophy are associated with a differential Epigenetic Profile in Advanced COPD.
Pulmonary Disease, Chronic Obstructive
Role of Non-Coding RNAs in Lung Circadian Clock Related Diseases.
Pulmonary Disease, Chronic Obstructive
The Protective Effect of HBO1 on Cigarette Smoke Extract-Induced Apoptosis in Airway Epithelial Cells.
Pulmonary Disease, Chronic Obstructive
The Role of the Body Clock in Asthma and COPD: Implication for Treatment.
Pulmonary Disease, Chronic Obstructive
Tiotropium Increases PPAR? and Decreases CREB in Cells Isolated from Induced Sputum of COPD Patients.
Pulmonary Disease, Chronic Obstructive
[Analysis of the N-acetyltransferase 2 gene polymorphism in the patients with chronic obstructive pulmonary disease and in populations of the Volga-Ural region]
Pulmonary Disease, Chronic Obstructive
[Lung cancer and its epigenetics association with chronic obstructive pulmonary disease].
Pulmonary Embolism
Acute pulmonary embolism: comparison and integration of perfusion lung scintigraphy with multislice spiral CT.
Pulmonary Fibrosis
Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo.
Pulmonary Fibrosis
Plumbagin Suppresses Pulmonary Fibrosis via Inhibition of p300 Histone Acetyltransferase Activity.
Pulmonary Fibrosis
The circadian clock protein REVERB? inhibits pulmonary fibrosis development.
Pulmonary Fibrosis
The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.
Quadriplegia
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation.
Rabies
A reassessment of the evolutionary timescale of bat rabies viruses based upon glycoprotein gene sequences.
Radiation Fibrosis Syndrome
Protective effect of ?-lipoic acid against radiation-induced fibrosis in mice.
Rectal Neoplasms
Longer Intervals from Neoadjuvant Therapy to Rectal Cancer Surgery: The Clock is Ticking
.
Rectal Neoplasms
N-acetyltransferase 1 in colon and rectal cancer cases from an industrialized area.
Rectal Neoplasms
N-Acetyltransferase 2 and glutathione s-transferase M1 in colon and rectal cancer cases from an industrialized area.
Refractive Errors
Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms.
Refractive Errors
Visual Image Quality Impacts Circadian Rhythm-Related Gene Expression in Retina and in Choroid: A Potential Mechanism for Ametropias.
REM Sleep Behavior Disorder
Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder.
Renal Insufficiency
An observational study on disturbed peripheral circadian rhythms in hemodialysis patients.
Renal Insufficiency
Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.
Renal Insufficiency, Chronic
A molecular circadian clock operates in the parathyroid gland and is disturbed in chronic kidney disease associated bone and mineral disorder.
Renal Insufficiency, Chronic
Chrono-Drug Discovery and Development Based on Circadian Rhythm of Molecular, Cellular and Organ Level.
Renal Insufficiency, Chronic
Chronopharmacological strategies focused on chrono-drug discovery.
Renal Insufficiency, Chronic
Testicular dysfunction in experimental chronic renal insufficiency: a deficiency of nocturnal pineal N-acetyltransferase activity.
Renal Insufficiency, Chronic
The association between shift work and chronic kidney disease in manual labor workers using data from the Korea National Health and Nutrition Examination Survey (KNHANES 2011-2014).
Reperfusion Injury
Downregulation of P300/CBP-Associated Factor Attenuates Myocardial Ischemia-Reperfusion Injury Via Inhibiting Autophagy.
Restless Legs Syndrome
Association between restless legs syndrome and CLOCK and NPAS2 gene polymorphisms in schizophrenia.
Restless Legs Syndrome
Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders.
Retinal Degeneration
Aberrant histone acetylation, altered transcription, and retinal degeneration in a Drosophila model of polyglutamine disease are rescued by CREB-binding protein.
Retinal Degeneration
Circadian regulation of iodopsin and clock is altered in the retinal degeneration chicken retina.
Retinal Degeneration
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration.
Retinal Degeneration
Rapid, Dynamic Activation of Müller Glial Stem Cell Responses in Zebrafish.
Retinal Degeneration
The mPer1 clock gene expression in the rd mouse suprachiasmatic nucleus is affected by the retinal degeneration.
Retinal Detachment
Analysis of risk factors for the outcome of primary retinal reattachment surgery in phakic and pseudophakic eyes.
Retinal Detachment
Anatomic Success of Scleral Buckling for Rhegmatogenous Retinal Detachment - A Retrospective Study of 524 Cases.
Retinal Detachment
Bevacizumab for Coats' disease with exudative retinal detachment and risk of vitreoretinal traction.
Retinal Detachment
Combined Pars Plana Vitrectomy and Segmental Scleral Buckle for Rhegmatogenous Retinal Detachment with Inferior Retinal Breaks.
Retinal Detachment
Comparison of 1000-Centistoke versus 5000-Centistoke Silicone Oil in Complex Retinal Detachment Surgery.
Retinal Detachment
Correlation of Clinical Outcomes with Quantitative Polymerase Chain Reaction DNA Copy Number in Patients with Acute Retinal Necrosis.
Retinal Detachment
Features associated with surgical outcome in patients with stages 4 and 5 retinopathy of prematurity.
Retinal Detachment
Functional outcome and prognostic factors in 304 eyes managed by retinectomy.
Retinal Detachment
Interaction between surgical procedure for repairing retinal detachment and clinical risk factors for proliferative vitreoretinopathy.
Retinal Detachment
Pneumatic retinopexy for the repair of retinal detachments: a comprehensive review (1986-2007).
Retinal Detachment
Pneumatic retinopexy perfluoroethane (C2F6) in the treatment of rhegmatogenous retinal detachment.
Retinal Detachment
Predictors of enucleation in Coats disease: analysis of 259 eyes of 259 patients at a single center.
Retinal Detachment
Retinal detachment and convexity intracranial meningioma: an uncommon association.
Retinal Detachment
Retinal features predictive of progressive stage 4 retinopathy of prematurity.
Retinal Detachment
SCLERAL BUCKLING FOR PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT USING A NONCONTACT WIDE-ANGLE VIEWING SYSTEM WITH A CANNULA-BASED 27-G CHANDELIER ENDOILLUMINATOR.
Retinal Detachment
Severe proliferative vitreoretinopathy and retinal detachment. I. Initial clinical findings.
Retinal Detachment
STRICT POSTURING WITH OR WITHOUT BILATERAL PATCHING FOR POSTERIOR VITREOUS DETACHMENT-RELATED VITREOUS HEMORRHAGE.
Retinal Detachment
TRAUMATIC RETINAL DETACHMENT CAUSED BY NERF GUN SHOT IN A PEDIATRIC PATIENT.
Retinal Diseases
An allosteric peptide inhibitor of HIF-1? regulates hypoxia-induced retinal neovascularization.
Retinal Perforations
Anatomic, Visual and Financial Outcomes for Traditional and Nontraditional Primary Pneumatic Retinopexy for Retinal Detachment.
Retinal Perforations
Combined Pars Plana Vitrectomy and Segmental Scleral Buckle for Rhegmatogenous Retinal Detachment with Inferior Retinal Breaks.
Retinal Perforations
Interaction between surgical procedure for repairing retinal detachment and clinical risk factors for proliferative vitreoretinopathy.
Retinal Perforations
Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment in Pseudophakia.
Retinal Perforations
Pneumatic retinopexy for the repair of retinal detachments: a comprehensive review (1986-2007).
Retinal Perforations
Pneumatic retinopexy perfluoroethane (C2F6) in the treatment of rhegmatogenous retinal detachment.
Retinal Perforations
Pneumatic retinopexy versus scleral buckling: a randomised controlled trial.
Retinal Perforations
Primary vitrectomy with Densiron-68 for rhegmatogenous retinal detachment.
Retinal Perforations
Retinal detachment and convexity intracranial meningioma: an uncommon association.
Retinal Perforations
Rhegmatogenous Retinal Detachment after Intravitreal Injection of Anti-Vascular Endothelial Growth Factor.
Retinal Perforations
Sandwich Technique with Anterior Silicone Oil and Posterior Perfluorocarbon Liquid for Intraoperative Retinal Stabilization in Eyes with Large Retinal Breaks.
Retinal Perforations
Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR Study): recruitment list evaluation. Study report no. 2.
Retinal Perforations
SEQUENTIAL PNEUMATIC RETINOPEXIES FOR THE TREATMENT OF PRIMARY INFERIOR RHEGMATOGENOUS RETINAL DETACHMENTS WITH INFERIOR BREAKS: The Double-Bubble Approach.
Retinal Perforations
Severe proliferative vitreoretinopathy and retinal detachment. I. Initial clinical findings.
Retinal Perforations
Standardized echography (ultrasonography) for the detection and characterization of retinal detachment.
Retinal Perforations
The Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT).
Retinal Perforations
The Safety and Efficacy of Adjustable Postoperative Position after Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment.
Retinal Perforations
Time to Unplanned Return to the Operating Room and Associated Risk Factors in Patients With Surgical Retinal Detachment Repair.
Retinal Perforations
Vision-Related Functioning in Patients Undergoing Pneumatic Retinopexy vs Vitrectomy for Primary Rhegmatogenous Retinal Detachment: A Post Hoc Exploratory Analysis of the PIVOT Randomized Clinical Trial.
Retinal Perforations
[Giant retinal tears treated with lens sparing, bimanual 23 g vitrectomy without scleral buckle].
Retinitis
Correlation of Clinical Outcomes with Quantitative Polymerase Chain Reaction DNA Copy Number in Patients with Acute Retinal Necrosis.
Retinitis
The utility of entoptic perimetry as a screening test for cytomegalovirus retinitis.
Retinitis Pigmentosa
RNA Splicing Factor Mutations That Cause Retinitis Pigmentosa Result in Circadian Dysregulation.
Retinoblastoma
AMPK promotes mitochondrial biogenesis and function by phosphorylating the epigenetic factors DNMT1, RBBP7, and HAT1.
Retinoblastoma
Cell cycle-mediated regulation of smooth muscle alpha-actin gene transcription in fibroblasts and vascular smooth muscle cells involves multiple adenovirus E1A-interacting cofactors.
Retinoblastoma
Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells.
Retinoblastoma
Down-regulation of p300/CBP histone acetyltransferase activates a senescence checkpoint in human melanocytes.
Retinoblastoma
Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A.
Retinoblastoma
Human papillomavirus type 16 E7 protein increases acetylation of histone H3 in human foreskin keratinocytes.
Retinoblastoma
Inhibition of crystallin expression and induction of apoptosis by lens-specific E1A expression in transgenic mice.
Retinoblastoma
Mapping the interactions of adenoviral E1A proteins with the p160 nuclear receptor coactivator binding domain of CBP.
Retinoblastoma
N-acetyltransferase and protein synthesis modulate melatonin production by Y79 human retinoblastoma cells.
Retinoblastoma
Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.
Retinoblastoma
Requirement of an E1A-sensitive coactivator for long-range transactivation by the beta-globin locus control region.
Retinoblastoma
Synergistic role of E1A-binding proteins and tissue-specific transcription factors in differentiation.
Retinopathy of Prematurity
Expression and function of Delta-like ligand 4 in a rat model of retinopathy of prematurity.
Retinopathy of Prematurity
Limiting applications of cryotherapy for severe retinopathy of prematurity.
Retinopathy of Prematurity
Long-term results of cryotherapy for active stages of retinopathy of prematurity.
Retinopathy of Prematurity
Neovascularization grading methods in a rat model of retinopathy of prematurity.
Retrognathia
Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome.
Rett Syndrome
Circadian biology and sleep in monogenic neurological disorders and its potential application in drug discovery.
Rhinitis
Dose-dependent effects of budesonide aqueous nasal spray on symptoms in a daily nasal allergen challenge model.
Rhinitis, Allergic
Allergen-specific basophil reactivity exhibits daily variations in seasonal allergic rhinitis.
Rhinitis, Allergic
Asymmetric expression level of clock genes in left vs. right nasal mucosa in humans with and without allergies and in rats: Circadian characteristics and possible contribution to nasal cycle.
Rhinitis, Allergic
Period2 gene regulates diurnal changes of nasal symptoms in an allergic rhinitis mouse model.
Rhinitis, Allergic
[Principle of biological clock and its regulation on allergic rhinitis].
Rhinitis, Allergic, Seasonal
Allergen-specific basophil reactivity exhibits daily variations in seasonal allergic rhinitis.
ring-type e3 ubiquitin transferase deficiency
Functional Interaction of BRCA1 and CREBBP in Murine Hematopoiesis.
Rubinstein-Taybi Syndrome
A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.
Rubinstein-Taybi Syndrome
A case of Rubinstein-Taybi Syndrome with a CREB-binding protein gene mutation.
Rubinstein-Taybi Syndrome
A case with Rubinstein-Taybi syndrome: A novel frameshift mutation in the CREBBP gene.
Rubinstein-Taybi Syndrome
A Novel CREBBP in-Frame Deletion Variant in a Chinese Girl with Atypical Rubinstein-Taybi Syndrome Phenotypes.
Rubinstein-Taybi Syndrome
A novel EP300 mutation associated with Rubinstein-Taybi syndrome type 2 presenting as combined immunodeficiency.
Rubinstein-Taybi Syndrome
A novel mutation c.4003 G>C in the CREBBP gene in an adult female with Rubinstein-Taybi syndrome presenting with subtle dysmorphic features.
Rubinstein-Taybi Syndrome
A submicroscopic deletion involving part of the CREBBP gene detected by array-CGH in a patient with Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.
Rubinstein-Taybi Syndrome
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.
Rubinstein-Taybi Syndrome
Case Report: Low-Level Maternal Mosaicism of a Novel CREBBP Variant Causes Recurrent Rubinstein-Taybi Syndrome in Two Siblings of a Chinese Family.
Rubinstein-Taybi Syndrome
CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain.
Rubinstein-Taybi Syndrome
CBP regulates the differentiation of interneurons from ventral forebrain neural precursors during murine development.
Rubinstein-Taybi Syndrome
Characterization of 14 novel deletions underlying Rubinstein-Taybi syndrome: an update of the CREBBP deletion repertoire.
Rubinstein-Taybi Syndrome
Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish.
Rubinstein-Taybi Syndrome
Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.
Rubinstein-Taybi Syndrome
Chromosome 16p13.3 Contiguous Gene Deletion Syndrome including the SLX4, DNASE1, TRAP1, and CREBBP Genes Presenting as a Relatively Mild Rubinstein-Taybi Syndrome Phenotype: A Case Report of a Saudi Boy.
Rubinstein-Taybi Syndrome
Clinical and molecular characterization of Rubinstein-Taybi syndrome patients carrying distinct novel mutations of the EP300 gene.
Rubinstein-Taybi Syndrome
Clinical exome sequencing identifies novel CREBBP variants in 18 Chinese Rubinstein-Taybi Syndrome kids with high frequency of polydactyly.
Rubinstein-Taybi Syndrome
Coffin-Siris syndrome with café-au-lait spots, obesity and hyperinsulinism caused by a mutation in the ARID1B gene.
Rubinstein-Taybi Syndrome
Comprehensive screening of CREB-binding protein gene mutations among patients with Rubinstein-Taybi syndrome using denaturing high-performance liquid chromatography.
Rubinstein-Taybi Syndrome
Confirmation of a new phenotype in an individual with a variant in the last part of exon 30 of CREBBP.
Rubinstein-Taybi Syndrome
Confirmation of EP300 gene mutations as a rare cause of Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
CREB-binding protein (CREBBP) and preeclampsia: a new promising target gene.
Rubinstein-Taybi Syndrome
CREBBP and EP300 mutational spectrum and clinical presentations in a cohort of Swedish patients with Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
CREBBP gene mutation in an infant with Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
CREBBP mutations in individuals without Rubinstein-Taybi syndrome phenotype.
Rubinstein-Taybi Syndrome
CREBBP Re-arrangements affect protein function and lead to aberrant neuronal differentiation.
Rubinstein-Taybi Syndrome
Cryptic microdeletion of the CREBBP gene from t(1;16) (p36.2;p13.3) as a novel genetic defect causing Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Disruption of the CREBBP gene and decreased expression of CREB, NF?B p65, c-JUN, c-FOS, BCL2 and c-MYC suggest immune dysregulation.
Rubinstein-Taybi Syndrome
DNA sequencing of CREBBP demonstrates mutations in 56% of patients with Rubinstein-Taybi syndrome (RSTS) and in another patient with incomplete RSTS.
Rubinstein-Taybi Syndrome
Duplication 16p13.3 and the CREBBP gene: confirmation of the phenotype.
Rubinstein-Taybi Syndrome
Duplications of the critical Rubinstein-Taybi deletion region on chromosome 16p13.3 cause a novel recognizable syndrome.
Rubinstein-Taybi Syndrome
Epigenetic factors in intellectual disability: the Rubinstein-Taybi syndrome as a paradigm of neurodevelopmental disorder with epigenetic origin.
Rubinstein-Taybi Syndrome
Exome Sequencing Identification of EP300 Mutation in a Proband with Coloboma and Imperforate Anus: Possible Expansion of the Phenotypic Spectrum of Rubinstein-Taybi Syndrome.
Rubinstein-Taybi Syndrome
Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.
Rubinstein-Taybi Syndrome
Expanding the phenotype associated to KMT2A variants: overlapping clinical signs between Wiedemann-Steiner and Rubinstein-Taybi syndromes.
Rubinstein-Taybi Syndrome
Expanding the phenotypic spectrum in EP300-related Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Fetal phenotype of Rubinstein-Taybi syndrome caused by CREBBP mutations.
Rubinstein-Taybi Syndrome
First case of Rubinstein-Taybi syndrome with desquamation associated with a novel mutation in the bromodomain of the CREBBP gene.
Rubinstein-Taybi Syndrome
First case report of inherited Rubinstein-Taybi syndrome associated with a novel EP300 variant.
Rubinstein-Taybi Syndrome
Floating-Harbor syndrome and polycystic kidneys associated with SRCAP mutation.
Rubinstein-Taybi Syndrome
Fluorescein angiography findings in a case of Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Further case of Rubinstein-Taybi syndrome due to a deletion in EP300.
Rubinstein-Taybi Syndrome
Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A?>?T, p.(Lys1277*).
Rubinstein-Taybi Syndrome
Generation of three iPSC lines (IAIi002, IAIi004, IAIi003) from Rubinstein-Taybi syndrome 1 patients carrying CREBBP non sense c.4435G>T, p.(Gly1479*) and c.3474G>A, p.(Trp1158*) and missense c.4627G>T, p.(Asp1543Tyr) mutations.
Rubinstein-Taybi Syndrome
Genes for RNA-binding proteins involved in neural-specific functions and diseases are downregulated in Rubinstein-Taybi iNeurons.
Rubinstein-Taybi Syndrome
Genetic heterogeneity in Rubinstein-Taybi syndrome: delineation of the phenotype of the first patients carrying mutations in EP300.
Rubinstein-Taybi Syndrome
Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.
Rubinstein-Taybi Syndrome
Genome-wide sequencing expands the phenotypic spectrum of EP300 variants.
Rubinstein-Taybi Syndrome
Genotype-phenotype specificity in Menke-Hennekam syndrome caused by missense variants in exon 30 or 31 of CREBBP.
Rubinstein-Taybi Syndrome
High frequency of mosaic CREBBP deletions in Rubinstein-Taybi syndrome patients and mapping of somatic and germ-line breakpoints.
Rubinstein-Taybi Syndrome
Histone Deacetylase Inhibitors Ameliorate Morphological Defects and Hypoexcitability of iPSC-Neurons from Rubinstein-Taybi Patients.
Rubinstein-Taybi Syndrome
Hyperinsulinism in an individual with an EP300 variant of Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Identification of a novel de novo mutation of CREBBP in a patient with Rubinstein-Taybi syndrome by targeted next-generation sequencing: a case report.
Rubinstein-Taybi Syndrome
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's disease.
Rubinstein-Taybi Syndrome
Insights into genotype-phenotype correlations from CREBBP point mutation screening in a cohort of 46 Rubinstein-Taybi syndrome patients.
Rubinstein-Taybi Syndrome
Insights into the Role of the Microbiota and of Short-Chain Fatty Acids in Rubinstein-Taybi Syndrome.
Rubinstein-Taybi Syndrome
Interstitial 16p13.3 microduplication: case report and critical review of genotype-phenotype correlation.
Rubinstein-Taybi Syndrome
Interstitial duplication of 22q13.2 in a girl with short stature, impaired speech and language, and dysmorphism.
Rubinstein-Taybi Syndrome
Introduction of a de novo Creb-binding protein gene mutation in sperm to produce a Rubinstein-Taybi syndrome model using inbred C57BL/6 mice.
Rubinstein-Taybi Syndrome
iPSC-derived neurons of CREBBP- and EP300-mutated Rubinstein-Taybi syndrome patients show morphological alterations and hypoexcitability.
Rubinstein-Taybi Syndrome
Letter to the Editor: A Novel Mutation in the CREBBP Gene of a Korean Girl with Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Loss of CBP acetyltransferase activity by PHD finger mutations in Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Molecular studies in 10 cases of Rubinstein-Taybi syndrome, including a mild variant showing a missense mutation in codon 1175 of CREBBP.
Rubinstein-Taybi Syndrome
Multiplex ligation-dependent probe amplification detection of an unknown large deletion of the CREB-binding protein gene in a patient with Rubinstein-Taybi Syndrome.
Rubinstein-Taybi Syndrome
Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.
Rubinstein-Taybi Syndrome
Mutations in CREBBP and EP300 genes affect DNA repair of oxidative damage in Rubinstein-Taybi syndrome cells.
Rubinstein-Taybi Syndrome
Mutations in SRCAP, encoding SNF2-related CREBBP activator protein, cause Floating-Harbor syndrome.
Rubinstein-Taybi Syndrome
Novel Findings in Floating-Harbor Syndrome and a Mini-Review of the Literature.
Rubinstein-Taybi Syndrome
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
Rubinstein-Taybi Syndrome
Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.
Rubinstein-Taybi Syndrome
Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.
Rubinstein-Taybi Syndrome
Rubinstein Taybi Syndrome in an Indian Child due to EP300 Gene Mutation.
Rubinstein-Taybi Syndrome
Rubinstein Taybi Syndrome in an Indian Child due to EP300 Gene Mutation: Correspondence.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome and CREBBP c.201 202delTA mutation: a case presenting with varicella meningoencephalitis.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome and Hirschsprung disease in a patient harboring an intragenic deletion of the CREBBP gene.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome associated with Chiari type I malformation caused by a large 16p13.3 microdeletion: a contiguous gene syndrome?
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome predisposing to non-WNT, non-SHH, group 3 medulloblastoma.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome with multiple pilomatricomas: The first case diagnosed by CREBBP mutation analysis.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi syndrome with normal FISH result and CREBBP gene analysis: a case report.
Rubinstein-Taybi Syndrome
Rubinstein-Taybi Syndrome: spectrum of CREBBP mutations in Italian patients.
Rubinstein-Taybi Syndrome
Screening for partial deletions in the CREBBP gene in Rubinstein-Taybi syndrome patients using multiplex PCR/liquid chromatography.
Rubinstein-Taybi Syndrome
Screening of a large Rubinstein-Taybi cohort identified many novel variants and emphasizes the importance of the CREBBP histone acetyltransferase domain.
Rubinstein-Taybi Syndrome
Secondary hemophagocytic lymphohystiocytosis in a Rubinstein Taybi syndrome patient.
Rubinstein-Taybi Syndrome
Simulations suggest pharmacological methods for rescuing long-term potentiation.
Rubinstein-Taybi Syndrome
Spectrum of CREBBP gene dosage anomalies in Rubinstein-Taybi syndrome patients.
Rubinstein-Taybi Syndrome
Spectrum of CREBBP mutations in Indian patients with Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Testing and improving experimental parameters for the use of low molecular weight targets in array-CGH experiments.
Rubinstein-Taybi Syndrome
Tissue-specific mosaicism in a patient with Rubinstein-Taybi syndrome and CREBBP exon 1 duplication.
Rubinstein-Taybi Syndrome
Transcriptome Analysis of iPSC-Derived Neurons from Rubinstein-Taybi Patients Reveals Deficits in Neuronal Differentiation.
Rubinstein-Taybi Syndrome
Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage.
Rubinstein-Taybi Syndrome
Two patients with EP300 mutations and facial dysmorphism different from the classic Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Variation in microdeletions of the cyclic AMP-responsive element-binding protein gene at chromosome band 16p13.3 in the Rubinstein-Taybi syndrome.
Rubinstein-Taybi Syndrome
Whole Exome Sequencing for a Patient with Rubinstein-Taybi Syndrome Reveals de Novo Variants besides an Overt CREBBP Mutation.
Rubinstein-Taybi Syndrome
[Clinical features of Rubinstein-Taybi syndrome and novel mutation in the CREBBP gene: an analysis of one case].
Salmonella Infections
Involvement of TIP60 acetyltransferase in intracellular Salmonella replication.
Sarcoma
Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis.
Sarcoma
Daily rhythms are retained both in spontaneously developed sarcomas and in xenografts grown in immunocompromised SCID mice.
Sarcoma
Direct visualization of the conformational change of FUS/TLS upon binding to promoter-associated non-coding RNA.
Sarcoma
EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function.
Sarcoma
Fusion of the AHRR and NCOA2 genes through a recurrent translocation t(5;8)(p15;q13) in soft tissue angiofibroma results in upregulation of aryl hydrocarbon receptor target genes.
Sarcoma
General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus.
Sarcoma
Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest.
Sarcoma
Investigation on the genomic characterization of uterine sarcoma for rAd-p53 combined with chemotherapy treatment.
Sarcoma 180
Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.
Sarcoma 37
N-acetyltransferase activity as a possible criterion in prognosing the anti-tumor effect of cyclophosphamide.
Sarcoma, Clear Cell
EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function.
Sarcopenia
Ageing in relation to skeletal muscle dysfunction: redox homoeostasis to regulation of gene expression.
Sarcopenia
Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction.
Sarcopenia
The Role of the Molecular Clock in Promoting Skeletal Muscle Growth and Protecting against Sarcopenia.
Sarcopenia
The Role of the Molecular Clock in Skeletal Muscle and What It Is Teaching Us About Muscle-Bone Crosstalk.
Schistosomiasis
The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays.
Scoliosis
Identical twin sisters with Rubinstein-Taybi syndrome associated with Chiari malformations and syrinx.
Scoliosis
Impaired Sleep, Circadian Rhythms and Neurogenesis in Diet-Induced Premature Aging.
Scoliosis
What are you synching about? Emerging complexity of Notch signaling in the segmentation clock.
Scotoma
Modified astigmatism dial diagram for locating eccentric fixation in patients with central scotoma.
Seizures
A fully-asynchronous low-power implantable seizure detector for self-triggering treatment.
Seizures
A single generalized seizure alters the amplitude, but not phase, of the circadian activity rhythm of the hamster.
Seizures
Acute and Chronic Electroconvulsive Seizures (ECS) Differentially Regulate the Expression of Epigenetic Machinery in the Adult Rat Hippocampus.
Seizures
Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy.
Seizures
Chronobiology of limbic seizures: Potential mechanisms and prospects of chronotherapy for mesial temporal lobe epilepsy.
Seizures
Clinical review: Continuous and simplified electroencephalography to monitor brain recovery after cardiac arrest.
Seizures
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy.
Seizures
Experiences of spiritual visitation and impregnation: potential induction by frequency-modulated transients from an adjacent clock.
Seizures
Identification of a Circadian Clock in the Inferior Colliculus and Its Dysregulation by Noise Exposure.
Seizures
Improvement of an automated neonatal seizure detector using a post-processing technique.
Seizures
Influence of etiology on treatment choices for neonatal seizures: A survey among pediatric neurologists.
Seizures
Molecular mechanism of circadian rhythmicity of seizures in temporal lobe epilepsy.
Seizures
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Seizures
Paroxysmal Movement Disorder and Epilepsy Caused by a De Novo Truncating Mutation in KAT6A.
Seizures
PER2 rs2304672, CLOCK rs1801260, and PER3 rs57875989 polymorphisms are not associated with juvenile myoclonic epilepsy.
Seizures
Rhythms of Core Clock Genes and Spontaneous Locomotor Activity in Post-Status Epilepticus Model of Mesial Temporal Lobe Epilepsy.
Seizures
The Molecular Genetic Interaction Between Circadian Rhythms and Susceptibility to Seizures and Epilepsy.
Seizures
Weighted performance metrics for automatic neonatal seizure detection using multi-scored EEG data.
Sepsis
Association of postnatal dexamethasone use and fungal sepsis in the development of severe retinopathy of prematurity and progression to laser therapy in extremely low-birth-weight infants.
Sepsis
Biocompatible valproic acid-coupled nanoparticles attenuate lipopolysaccharide-induced inflammation.
Sepsis
Daily Changes in The Expression of Clock Genes in Sepsis and Their Relation with Sepsis Outcome and Urinary Excretion of 6-Sulfatoximelatonin.
Sepsis
Day-night variation in heart rate variability changes induced by endotoxaemia in healthy volunteers.
Sepsis
Disruption of Circadian Rhythms and Delirium, Sleep Impairment and Sepsis in Critically ill Patients. Potential Therapeutic Implications for Increased Light-Dark Contrast and Melatonin Therapy in an ICU Environment.
Sepsis
Diurnal variation in endotoxin-induced mortality in mice: correlation with proinflammatory factors.
Sepsis
Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation.
Sepsis
Relative importance of heat-labile enterotoxin in the causation of severe diarrheal disease in the gnotobiotic piglet model by a strain of enterotoxigenic Escherichia coli that produces multiple enterotoxins.
Sepsis
Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin.
Sepsis
Uncoupling of peripheral and master clock gene rhythms by reversed feeding leads to an exacerbated inflammatory response after polymicrobial sepsis in mice.
Severe Acute Respiratory Syndrome
Current methods for diagnosis of human coronaviruses: pros and cons.
Severe Acute Respiratory Syndrome
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Severe Acute Respiratory Syndrome
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.
Shock, Cardiogenic
Arterial Lactate Assessment in Cardiogenic Shock: It Is High Time to Beat the Clock.
Shock, Cardiogenic
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
Shock, Septic
Bioinformatics Analysis of Gene Expression Profiles for Risk Prediction in Patients with Septic Shock.
Shock, Septic
Pediatric Septic Shock in the Emergency Department: Can We Set the Alarm Clock a Little Forward?
Sick Sinus Syndrome
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Sick Sinus Syndrome
The role of the calcium and the voltage clocks in sinoatrial node dysfunction.
Sick Sinus Syndrome
Tools to Keep the Clock Ticking: Molecular Approaches to Treat Sinus Node Dysfunction.
Silicosis
Matrix stiffness regulates ?-TAT1-mediated acetylation of ?-tubulin and promotes silica-induced epithelial-mesenchymal transition via DNA damage.
Skin Diseases
?-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis.
Skin Neoplasms
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis.
Skin Neoplasms
The Circadian Clock in Skin: Implications for Adult Stem Cells, Tissue Regeneration, Cancer, Aging, and Immunity.
Sleep Apnea Syndromes
Circadian rhythms in blood pressure, heart rate, hormones, and on polysomnographic parameters in severe obstructive sleep apnea syndrome patients: effect of continuous positive airway pressure.
Sleep Apnea, Obstructive
Alternations of Circadian Clock Genes Expression and Oscillation in Obstructive Sleep Apnea.
Sleep Apnea, Obstructive
Circadian Dysregulation: The Next Frontier in Obstructive Sleep Apnea Research.
Sleep Apnea, Obstructive
Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea.
Sleep Apnea, Obstructive
Relationship between HIF-1 and Circadian Clock Proteins in Obstructive Sleep Apnea Patients-Preliminary Study.
Sleep Apnea, Obstructive
The rat cerebral vasculature exhibits time-of-day-dependent oscillations in circadian clock genes and vascular function that are attenuated following obstructive sleep apnea.
Sleep Arousal Disorders
Circadian clock-deficient mice as a tool for exploring disease etiology.
Sleep Deprivation
A mathematical model of homeostatic regulation of sleep-wake cycles by hypocretin/orexin.
Sleep Deprivation
Acute Sleep Loss Induces Tissue-Specific Epigenetic and Transcriptional Alterations to Circadian Clock Genes in Men.
Sleep Deprivation
Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption.
Sleep Deprivation
Caffeine increases light responsiveness of the mouse circadian pacemaker.
Sleep Deprivation
Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons.
Sleep Deprivation
Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines.
Sleep Deprivation
Circadian clock resetting by sleep deprivation without exercise in Syrian hamsters: dark pulses revisited.
Sleep Deprivation
Circadian clock resetting by sleep deprivation without exercise in the Syrian hamster.
Sleep Deprivation
Circadian rhythm in plasma noradrenaline of healthy sleep-deprived subjects.
Sleep Deprivation
Circadian rhythms and depression: Human psychopathology and animal models.
Sleep Deprivation
Classifying Vulnerability to Sleep Deprivation Using Resting-State Functional MRI Graph Theory Metrics.
Sleep Deprivation
Computational modeling and analysis of the impacts of sleep deprivation on glucose stimulated insulin secretion.
Sleep Deprivation
Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation.
Sleep Deprivation
Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans.
Sleep Deprivation
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome.
Sleep Deprivation
Energy stores are not altered by long-term partial sleep deprivation in Drosophila melanogaster.
Sleep Deprivation
Higher Number of Night Shifts Associates with Good Perception of Work Capacity and Optimal Lung Function but Correlates with Increased Oxidative Damage and Telomere Attrition.
Sleep Deprivation
Identification of Genes Associated With Resilience/Vulnerability to Sleep Deprivation and Starvation in Drosophila.
Sleep Deprivation
Identification of Redeye, a new sleep-regulating protein whose expression is modulated by sleep amount.
Sleep Deprivation
Impact of COVID-19 social-distancing on sleep timing and duration during a university semester.
Sleep Deprivation
In Vivo Imaging of the Central and Peripheral Effects of Sleep Deprivation and Suprachiasmatic Nuclei Lesion on PERIOD-2 Protein in Mice.
Sleep Deprivation
Lithium acts to modulate abnormalities at behavioral, cellular and molecular levels in sleep deprivation induced mania-like behavior.
Sleep Deprivation
Long term effects of sleep deprivation on the mammalian circadian pacemaker.
Sleep Deprivation
Mechanisms of Rapid Antidepressant Effects of Sleep Deprivation Therapy: Clock Genes and Circadian Rhythms.
Sleep Deprivation
Mutual influence of sleep and circadian clocks on physiology and cognition.
Sleep Deprivation
New developments in sleep research: molecular genetics, gene expression, and systems neurobiology.
Sleep Deprivation
Overexpression of circadian clock protein cryptochrome (CRY) 1 alleviates sleep deprivation-induced vascular inflammation in a mouse model.
Sleep Deprivation
Sensorimotor and executive function slowing in anesthesiology residents after overnight shifts.
Sleep Deprivation
Seven days' around the clock exhaustive physical exertion combined with energy depletion and sleep deprivation primes circulating leukocytes.
Sleep Deprivation
Sexual dimorphism of sleep regulated by juvenile hormone signaling in Drosophila.
Sleep Deprivation
Shift work: health, performance and safety problems, traditional countermeasures, and innovative management strategies to reduce circadian misalignment.
Sleep Deprivation
Sleep and circadian rhythm disruption and recognition memory in schizophrenia.
Sleep Deprivation
Sleep deprivation and caffeine treatment potentiate photic resetting of the master circadian clock in a diurnal rodent.
Sleep Deprivation
Sleep deprivation and endothelial function: reconciling seminal evidence with recent perspectives.
Sleep Deprivation
Sleep deprivation as a method of chronotherapy in the treatment of depression.
Sleep Deprivation
Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains.
Sleep Deprivation
Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula.
Sleep Deprivation
Sleep deprivation influences diurnal variation of human time perception with prefrontal activity change: a functional near-infrared spectroscopy study.
Sleep Deprivation
Sleep Disturbance Induces Increased Cholesterol Level by NR1D1 Mediated CYP7A1 Inhibition.
Sleep Deprivation
Sleep homeostasis and the circadian clock: Do the circadian pacemaker and the sleep homeostat influence each other's functioning?
Sleep Deprivation
Sleep insufficiency, sleep health problems and performance in high school students.
Sleep Deprivation
Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex.
Sleep Deprivation
Sleep Problems in Narcolepsy and the Role of Hypocretin/Orexin Deficiency.
Sleep Deprivation
Stress response genes protect against lethal effects of sleep deprivation in Drosophila.
Sleep Deprivation
The cholinergic forebrain arousal system acts directly on the circadian pacemaker.
Sleep Deprivation
The circadian basis of mood disorders: recent developments and treatment implications.
Sleep Deprivation
The Circadian System: A Regulatory Feedback Network of Periphery and Brain.
Sleep Deprivation
The effect of chronotherapy on depressive symptoms. Evidence-based practice.
Sleep Deprivation
The effect of partial sleep deprivation on computer-based measures of fitness to drive.
Sleep Deprivation
The impact of sleep deprivation and nighttime light exposure on clock gene expression in humans.
Sleep Deprivation
The role of circadian rhythms in Obstructive Sleep Apnea symptoms and novel targets for treatment.
Sleep Deprivation
The wake maintenance zone shows task dependent changes in cognitive function following one night without sleep.
Sleep Deprivation
Ultradian rhythms in pituitary and adrenal hormones: their relations to sleep.
Sleep Deprivation
Work Habit-Related Sleep Debt; Insights From Factor Identification Analysis of Actigraphy Data.
Sleep Disorders, Circadian Rhythm
A circadian rhythm sleep disorder: melatonin resets the biological clock.
Sleep Disorders, Circadian Rhythm
A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference.
Sleep Disorders, Circadian Rhythm
A missense variation in human casein kinase I epsilon gene that induces functional alteration and shows an inverse association with circadian rhythm sleep disorders.
Sleep Disorders, Circadian Rhythm
Advancing human circadian rhythms with afternoon melatonin and morning intermittent bright light.
Sleep Disorders, Circadian Rhythm
Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome.
Sleep Disorders, Circadian Rhythm
Association study of a variable-number tandem repeat polymorphism in the clock gene PERIOD3 and Chronotype in Norwegian university students.
Sleep Disorders, Circadian Rhythm
Chronobiological disorders: current and prevalent conditions.
Sleep Disorders, Circadian Rhythm
Circadian Rhythm Sleep Disorders (CRSD) in psychiatry--a review.
Sleep Disorders, Circadian Rhythm
Circadian rhythmicity and the pharmacologic management of insomnia.
Sleep Disorders, Circadian Rhythm
Circadian rhythms in the CNS and peripheral clock disorders: human sleep disorders and clock genes.
Sleep Disorders, Circadian Rhythm
Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndrome.
Sleep Disorders, Circadian Rhythm
Clock polymorphisms and circadian rhythms phenotypes in a sample of the Brazilian population.
Sleep Disorders, Circadian Rhythm
Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder.
Sleep Disorders, Circadian Rhythm
Estimation methods for human circadian phase by use of peripheral tissues.
Sleep Disorders, Circadian Rhythm
Evaluation of circadian phenotypes utilizing fibroblasts from patients with circadian rhythm sleep disorders.
Sleep Disorders, Circadian Rhythm
From circadian clock mechanism to sleep disorders and jet lag: Insights from a computational approach.
Sleep Disorders, Circadian Rhythm
Jet lag and shift work sleep disorders: how to help reset the internal clock.
Sleep Disorders, Circadian Rhythm
Metabolic dysfunction and circadian rhythm abnormalities in adolescents with sleep disturbance.
Sleep Disorders, Circadian Rhythm
miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock.
Sleep Disorders, Circadian Rhythm
Modeling of a human circadian mutation yields insights into clock regulation by PER2.
Sleep Disorders, Circadian Rhythm
Modeling the mammalian circadian clock: sensitivity analysis and multiplicity of oscillatory mechanisms.
Sleep Disorders, Circadian Rhythm
Mutation screening of the human Clock gene in circadian rhythm sleep disorders.
Sleep Disorders, Circadian Rhythm
New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.
Sleep Disorders, Circadian Rhythm
Novel insights from genetic and molecular characterization of the human clock.
Sleep Disorders, Circadian Rhythm
Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome.
Sleep Disorders, Circadian Rhythm
PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders.
Sleep Disorders, Circadian Rhythm
Screening of clock gene polymorphisms demonstrates association of a PER3 polymorphism with morningness-eveningness preference and circadian rhythm sleep disorder.
Sleep Disorders, Circadian Rhythm
Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain.
Sleep Disorders, Circadian Rhythm
The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects.
Sleep Disorders, Circadian Rhythm
The circadian mutation PER2(S662G) is linked to cell cycle progression and tumorigenesis.
Sleep Disorders, Circadian Rhythm
Timing of sleep and its relationship with the endogenous melatonin rhythm.
Sleep Disorders, Circadian Rhythm
Total sleep deprivation study in delayed sleep-phase syndrome.
Sleep Disorders, Circadian Rhythm
When the body clock goes wrong: delayed sleep phase syndrome.
Sleep Disorders, Circadian Rhythm
[Advanced sleep phase syndrome (ASPS) and delayed sleep phase syndrome (DSPS)]
Sleep Disorders, Circadian Rhythm
[Delayed wakefulness-sleep rhythm syndrome and melatonin. Synthesis of existing studies]
Sleep Disorders, Circadian Rhythm
[Diagnosis and comorbidities of Circadian Rhythm Sleep Disorders].
Sleep Disorders, Circadian Rhythm
[Functional polymorphisms in clock genes and circadian rhythm sleep disorders]
Sleep Disorders, Intrinsic
Molecular genetics of timing in intrinsic circadian rhythm sleep disorders.
Sleep Initiation and Maintenance Disorders
3111T/C Clock Gene Polymorphism in Women with Insomnia.
Sleep Initiation and Maintenance Disorders
3111T/C clock gene polymorphism is not associated with sleep disturbances in untreated depressed patients.
Sleep Initiation and Maintenance Disorders
A benzodiazepine used in the treatment of insomnia phase-shifts the mammalian circadian clock.
Sleep Initiation and Maintenance Disorders
Advances in the pharmacological management of non-24-h sleep-wake disorder.
Sleep Initiation and Maintenance Disorders
Applying the quarter-hour rule: can people with insomnia accurately estimate 15-min periods during the sleep-onset phase?
Sleep Initiation and Maintenance Disorders
Association of 3111T/C Polymorphism of the Clock Gene with Circadian Rhythm of Melatonin in Menopausal Women with Insomnia.
Sleep Initiation and Maintenance Disorders
Association of the melatonin circadian rhythms with clock 3111T/C gene polymorphism in Caucasian and Asian menopausal women with insomnia.
Sleep Initiation and Maintenance Disorders
Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock.
Sleep Initiation and Maintenance Disorders
Circadian Phase and Phase Angle Disorders in Primary Insomnia.
Sleep Initiation and Maintenance Disorders
Circadian rhythm sleep disorders and phototherapy.
Sleep Initiation and Maintenance Disorders
Circadian rhythm sleep disorders: pathophysiology and potential approaches to management.
Sleep Initiation and Maintenance Disorders
Clinical efficacy of dim light melatonin onset testing in diagnosing delayed sleep phase syndrome.
Sleep Initiation and Maintenance Disorders
Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients.
Sleep Initiation and Maintenance Disorders
CLOCK may Predict the Response to Fluvoxamine Treatment in Japanese Major Depressive Disorder Patients.
Sleep Initiation and Maintenance Disorders
Diagnosis and Treatment of Non-24-h Sleep-Wake Disorder in the Blind.
Sleep Initiation and Maintenance Disorders
Digital CBT Reduces Insomnia Symptoms Round the Clock.
Sleep Initiation and Maintenance Disorders
Disruption of the circadian system by environmental factors: Effects of hypoxia, magnetic fields and general anesthetics agents.
Sleep Initiation and Maintenance Disorders
Disruption of the circadian timing systems: molecular mechanisms in mood disorders.
Sleep Initiation and Maintenance Disorders
Effects of CLOCK gene variants and early stress on hopelessness and suicide in bipolar depression.
Sleep Initiation and Maintenance Disorders
Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism.
Sleep Initiation and Maintenance Disorders
Genetic diversity patterns at the human clock gene period 2 are suggestive of population-specific positive selection.
Sleep Initiation and Maintenance Disorders
Genetic variants and abnormal processing of pre-miR-182, a circadian clock modulator, in major depression patients with late insomnia.
Sleep Initiation and Maintenance Disorders
Genetics of the sleep-wake cycle and its disorders.
Sleep Initiation and Maintenance Disorders
Human CRY1 variants associate with attention deficit/hyperactivity disorder.
Sleep Initiation and Maintenance Disorders
Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism.
Sleep Initiation and Maintenance Disorders
Insomnia, biological clock, and the bedtime decision: an economic perspective.
Sleep Initiation and Maintenance Disorders
Lipid peroxidation depends on the clock 3111T/C gene polymorphism in menopausal women with Insomnia.
Sleep Initiation and Maintenance Disorders
Manipulation of a central circadian clock regulating behavioral and endocrine rhythms with a short-acting benzodiazepine used in the treatment of insomnia.
Sleep Initiation and Maintenance Disorders
Mechanisms underlying the association between insomnia, anxiety, and depression in adolescence: Implications for behavioral sleep interventions.
Sleep Initiation and Maintenance Disorders
Methylphenidate modifies the motion of the circadian clock.
Sleep Initiation and Maintenance Disorders
Psychiatric aspects of jet lag: review and hypothesis.
Sleep Initiation and Maintenance Disorders
Racial/Ethnic Differences in the Longitudinal Effects of Fear of Falling on Falls.
Sleep Initiation and Maintenance Disorders
Sleep Disturbance and Altered Expression of Circadian Clock Genes in Patients With Sudden Sensorineural Hearing Loss.
Sleep Initiation and Maintenance Disorders
Sleep: important considerations in management of pain.
Sleep Initiation and Maintenance Disorders
Sleeping with the enemy: clock monitoring in the maintenance of insomnia.
Sleep Initiation and Maintenance Disorders
The association between shift work and possible obstructive sleep apnea: a systematic review and meta-analysis.
Sleep Initiation and Maintenance Disorders
The clock as a focus of selective attention in those with primary insomnia: an experimental study using a modified Posner paradigm.
Sleep Initiation and Maintenance Disorders
The effect of circadian preferences on insomnia severity and depressive symptoms via sleep hygiene in older adults with depression and healthy controls.
Sleep Initiation and Maintenance Disorders
The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.
Sleep Initiation and Maintenance Disorders
The human circadian system in normal and disordered sleep.
Sleep Initiation and Maintenance Disorders
The melatonin agonist ramelteon induces duration-dependent clock gene expression through cAMP signaling in pancreatic INS-1 ?-cells.
Sleep Initiation and Maintenance Disorders
The perspective of management of sleep disorders in Japan.
Sleep Initiation and Maintenance Disorders
Trait anxiety and sleep-onset insomnia: evaluation of treatment using anxiety management training.
Sleep Initiation and Maintenance Disorders
[Diagnosis and comorbidities of Circadian Rhythm Sleep Disorders].
Sleep Initiation and Maintenance Disorders
[Sleep quality and daytime sleepiness in schizophrenia spectrum disorders during antipsychotic treatment]
Sleep Wake Disorders
A circadian rhythm sleep disorder: melatonin resets the biological clock.
Sleep Wake Disorders
A missense variation in human casein kinase I epsilon gene that induces functional alteration and shows an inverse association with circadian rhythm sleep disorders.
Sleep Wake Disorders
Alterations of sleep quality and circadian rhythm genes expression in elderly thyroid nodule patients and risks associated with thyroid malignancy.
Sleep Wake Disorders
Analysis of the molecular pathophysiology of sleep disorders relevant to a disturbed biological clock.
Sleep Wake Disorders
Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome.
Sleep Wake Disorders
Association of the melatonin circadian rhythms with clock 3111T/C gene polymorphism in Caucasian and Asian menopausal women with insomnia.
Sleep Wake Disorders
Association study of a variable-number tandem repeat polymorphism in the clock gene PERIOD3 and Chronotype in Norwegian university students.
Sleep Wake Disorders
Chrono-Drug Discovery and Development Based on Circadian Rhythm of Molecular, Cellular and Organ Level.
Sleep Wake Disorders
Circadian clock genes: Non-circadian roles in sleep, addiction, and psychiatric disorders?
Sleep Wake Disorders
Circadian disruption induced by tumor development in a murine model of melanoma.
Sleep Wake Disorders
Circadian Regulation of the Hepatic Endobiotic and Xenobitoic Detoxification Pathways: The Time Matters.
Sleep Wake Disorders
Circadian rhythm sleep disorders: pathophysiology and potential approaches to management.
Sleep Wake Disorders
Circadian rhythms and depression: Human psychopathology and animal models.
Sleep Wake Disorders
Circadian rhythms in the CNS and peripheral clock disorders: human sleep disorders and clock genes.
Sleep Wake Disorders
Circadian-relevant genes are highly polymorphic in autism spectrum disorder patients.
Sleep Wake Disorders
CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson's Disease.
Sleep Wake Disorders
Crystal structure of the dopamine N-acetyltransferase-acetyl-CoA complex provides insights into the catalytic mechanism.
Sleep Wake Disorders
Cyclic alternating pattern in polysomnography: what is it and what does it mean?
Sleep Wake Disorders
Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder.
Sleep Wake Disorders
Disruption of the circadian system by environmental factors: Effects of hypoxia, magnetic fields and general anesthetics agents.
Sleep Wake Disorders
Dose response curve for the phase-shifting effect of triazolam on the mammalian circadian clock.
Sleep Wake Disorders
Effect of melatonin administration on the PER1 and BMAL1 clock genes in patients with Parkinson's disease.
Sleep Wake Disorders
Effects of Cryptochrome-modulating compounds on circadian behavioral rhythms in zebrafish.
Sleep Wake Disorders
Effects of Occupational Stress and Circadian CLOCK Gene Polymorphism on Sleep Quality of Oil Workers in Xinjiang, China.
Sleep Wake Disorders
Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system.
Sleep Wake Disorders
Estimation methods for human circadian phase by use of peripheral tissues.
Sleep Wake Disorders
Evaluation of circadian phenotypes utilizing fibroblasts from patients with circadian rhythm sleep disorders.
Sleep Wake Disorders
From circadian clock mechanism to sleep disorders and jet lag: Insights from a computational approach.
Sleep Wake Disorders
Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism.
Sleep Wake Disorders
Intrinsic period and light intensity determine the phase relationship between melatonin and sleep in humans.
Sleep Wake Disorders
Jet lag and shift work sleep disorders: how to help reset the internal clock.
Sleep Wake Disorders
Light exposure in the natural environment: relevance to mood and sleep disorders.
Sleep Wake Disorders
Light therapy for better mood and insulin sensitivity in patients with major depression and type 2 diabetes: a randomised, double-blind, parallel-arm trial.
Sleep Wake Disorders
Metabolic dysfunction and circadian rhythm abnormalities in adolescents with sleep disturbance.
Sleep Wake Disorders
Mutation screening of the human Clock gene in circadian rhythm sleep disorders.
Sleep Wake Disorders
New approaches in the management of insomnia: weighing the advantages of prolonged-release melatonin and synthetic melatoninergic agonists.
Sleep Wake Disorders
Phenotypic effects of genetic variability in human clock genes on circadian and sleep parameters.
Sleep Wake Disorders
PPARalpha is a potential therapeutic target of drugs to treat circadian rhythm sleep disorders.
Sleep Wake Disorders
Regulation of Circadian Clock Genes on Sleep Disorders in Traumatic Brain Injury Patients.
Sleep Wake Disorders
Relationship between Mental Health, the CLOCK Gene, and Sleep Quality in Surgical Nurses: A Cross-Sectional Study.
Sleep Wake Disorders
Review: Identification and Management of Circadian Rhythm Sleep Disorders as a Transdiagnostic Feature in Child and Adolescent Psychiatry.
Sleep Wake Disorders
Role of a circadian-relevant gene NR1D1 in brain development: possible involvement in the pathophysiology of autism spectrum disorders.
Sleep Wake Disorders
Screening of clock gene polymorphisms demonstrates association of a PER3 polymorphism with morningness-eveningness preference and circadian rhythm sleep disorder.
Sleep Wake Disorders
Stability of d-luciferin for bioluminescence to detect gene expression in freely moving mice for long durations.
Sleep Wake Disorders
The Association of Sleep Disorders, Obesity and Sleep-Related Hypoxia with Cancer.
Sleep Wake Disorders
The brain's master circadian clock: implications and opportunities for therapy of sleep disorders.
Sleep Wake Disorders
The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.
Sleep Wake Disorders
Timing of sleep and its relationship with the endogenous melatonin rhythm.
Sleep Wake Disorders
[Advanced sleep phase syndrome (ASPS) and delayed sleep phase syndrome (DSPS)]
Sleep Wake Disorders
[Functional polymorphisms in clock genes and circadian rhythm sleep disorders]
Small Cell Lung Carcinoma
Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition.
Small Cell Lung Carcinoma
DrugSniper, a Tool to Exploit Loss-Of-Function Screens, Identifies CREBBP as a Predictive Biomarker of VOLASERTIB in Small Cell Lung Carcinoma (SCLC).
Small Cell Lung Carcinoma
KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer.
Small Cell Lung Carcinoma
Preferential sensitivity to HDAC inhibitors in tumors with CREBBP mutation.
Small Cell Lung Carcinoma
SOX4, SOX11 and PAX6 mRNA expression was identified as a (prognostic) marker for the aggressiveness of neuroendocrine tumors of the lung by using next-generation expression analysis (NanoString).
Smith-Magenis Syndrome
Alteration of the circadian clock in children with Smith-Magenis syndrome.
Smith-Magenis Syndrome
Beta 1-adrenergic antagonists and melatonin reset the clock and restore sleep in a circadian disorder, Smith-Magenis syndrome.
Smith-Magenis Syndrome
Phase advance of circadian rhythms in Smith-Magenis syndrome: a case study in an adult man.
Smith-Magenis Syndrome
Smith-Magenis syndrome results in disruption of CLOCK gene transcription and reveals an integral role for RAI1 in the maintenance of circadian rhythmicity.
Sotos Syndrome
Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1.
Specific Language Disorder
De novo KAT6B mutation, Say-Barber-Biesecker-Young-Simpson syndrome, and specific language impairment.
Spina Bifida Occulta
EP300-related Rubinstein-Taybi syndrome: Highlighted rare phenotypic findings and a genotype-phenotype meta-analysis of 74 patients.
Spinal Cord Injuries
Elevated Serum Melatonin under Constant Darkness Enhances Neural Repair in Spinal Cord Injury through Regulation of Circadian Clock Proteins Expression.
Spinal Dysraphism
Orofacial clefts and spina bifida: N-acetyltransferase phenotype, maternal smoking, and medication use.
Spinocerebellar Ataxias
Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.
Spinocerebellar Ataxias
Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.
Spinocerebellar Ataxias
Histone acetylation, acetyltransferases, and ataxia-alteration of histone acetylation and chromatin dynamics is implicated in the pathogenesis of polyglutamine-expansion disorders.
Spinocerebellar Ataxias
Partial Loss of Tip60 Slows Midstage Neurodegeneration in a Spinocerebellar Ataxia Type 1 (SCA1) Mouse Model.
Spinocerebellar Ataxias
Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity.
Spinocerebellar Ataxias
RORalpha-mediated Purkinje cell development determines disease severity in adult SCA1 mice.
Spondylitis, Ankylosing
Efficacy research of salazosulfamide in ankylosing spondylitis and NAT1 gene polymorphism.
Spondylitis, Ankylosing
Imbalance between HAT and HDAC Activities in the PBMCs of Patients with Ankylosing Spondylitis or Rheumatoid Arthritis and Influence of HDAC Inhibitors on TNF Alpha Production.
Squamous Cell Carcinoma of Head and Neck
A role for the clock period circadian regulator 2 gene in regulating the clock gene network in human oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Altered expression of circadian clock genes in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Circadian (De)regulation in Head and Neck Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Circadian clock gene Per2 plays an important role in cell proliferation, apoptosis and cell cycle progression in human oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Genetic polymorphism of N-acetyltransferase 2 in the susceptibility to laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Impact of Epigenetic Regulation on Head and Neck Squamous Cell Carcinoma.
Squamous Cell Carcinoma of Head and Neck
Loss of the clock gene Per1 promotes oral squamous cell carcinoma progression via the AKT/mTOR pathway.
Squamous Cell Carcinoma of Head and Neck
Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
Overexpression of retinoic acid receptor beta induces growth arrest and apoptosis in oral cancer cell lines.
Squamous Cell Carcinoma of Head and Neck
Overexpression of the clock gene Per2 suppresses oral squamous cell carcinoma progression by activating autophagy via the PI3K/AKT/mTOR pathway.
Squamous Cell Carcinoma of Head and Neck
PER1 and CLOCK are potential circulating biomarkers for head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Prevalence of high-risk human papillomavirus infection and cancer gene mutations in nonmalignant tonsils.
Squamous Cell Carcinoma of Head and Neck
RUVBL1 is an amplified epigenetic factor promoting proliferation and inhibiting differentiation program in head and neck squamous cancers.
Squamous Cell Carcinoma of Head and Neck
The circadian clock gene PER2 plays an important role in tumor suppression through regulating tumor-associated genes in human oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
The clock gene PER1 suppresses expression of tumor-related genes in human oral squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
The head and neck cancer cell oncogenome: a platform for the development of precision molecular therapies.
Squamous Cell Carcinoma of Head and Neck
[Effect of clock gene PER1 knockdown on clock gene networks in human oral squamous cell carcinoma].
Squamous Cell Carcinoma of Head and Neck
[Effects and mechanism of the circadian clock gene Per1 on the proliferation, apoptosis, cycle, and tumorigenicity in vivo of human oral squamous cell carcinoma].
ST Elevation Myocardial Infarction
Abnormal circadian rhythms are associated with plaque instability in acute coronary syndrome patients.
ST Elevation Myocardial Infarction
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
ST Elevation Myocardial Infarction
Working Against the Clock: A Model for Rural STEMI Triage.
Starvation
Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer.
Starvation
BAG6/BAT3 modulates autophagy by affecting EP300/p300 intracellular localization.
Starvation
Combination of starvation interval and food volume determines the phase of liver circadian rhythm in Per2::Luc knock-in mice under two meals per day feeding.
Starvation
Effects of fasting and re-feeding on the expression of dec1, per1, and other clock-related genes.
Starvation
Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation.
Starvation
Neuron-specific overexpression of core clock genes improves stress-resistance and extends lifespan of Drosophila melanogaster.
Starvation
Recruitment of the NuA4 complex poises the PHO5 promoter for chromatin remodeling and activation.
Starvation
Regulation of gustatory physiology and appetitive behavior by the Drosophila circadian clock.
Starvation
Response of the circadian clock and diel starch turnover to one day of low light or low CO2.
Starvation
SIRT1 and circadian gene expression in pancreatic ductal adenocarcinoma: Effect of starvation.
Starvation
The Drosophila takeout gene is a novel molecular link between circadian rhythms and feeding behavior.
Starvation
The Influence of Short-term Fasting on Muscle Growth and Fiber Hypotrophy Regulated by the Rhythmic Expression of Clock Genes and Myogenic Factors in Nile Tilapia.
Starvation
The sleep-feeding conflict: Understanding behavioral integration through genetic analysis in Drosophila.
Starvation
The small G protein RAS2 is involved in the metabolic compensation of the circadian clock in the circadian model Neurospora crassa.
Starvation
Time to grow: circadian regulation of growth and metabolism in photosynthetic organisms.
Starvation
Time-imposed daily restricted feeding induces rhythmic expression of Fgf21 in white adipose tissue of mice.
Starvation
[Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics--CYP2E1 substrates in rats]
Stomach Neoplasms
A pilot study investigating the role of NAT1 and NAT2 polymorphisms in gastric adenocarcinoma.
Stomach Neoplasms
Adenovirus vector-mediated upregulation of spermidine /spermine N-acetyltransferase impairs human gastric cancer growth in vitro and in vivo.
Stomach Neoplasms
Altered expression profiles of clock genes hPer1 and hPer2 in peripheral blood mononuclear cells of cancer patients undergoing surgery.
Stomach Neoplasms
Combining multi-dimensional data to identify key genes and pathways in gastric cancer.
Stomach Neoplasms
E7386, a Selective Inhibitor of the Interaction between ?-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
Stomach Neoplasms
Effects of dietary factors and the NAT2 acetylator status on gastric cancer in Koreans.
Stomach Neoplasms
Expression of hMOF, but not HDAC4, is responsible for the global histone H4K16 acetylation in gastric carcinoma.
Stomach Neoplasms
Genotypes of glutathione S-transferase M1 and N-acetyltransferase 2 in Japanese patients with gastric cancer.
Stomach Neoplasms
Histone acetyltransferase p300/CBP inhibitor C646 blocks the survival and invasion pathways of gastric cancer cell lines.
Stomach Neoplasms
Histone Deacetylases (HDACs) in gastric cancer: An update of their emerging prognostic and therapeutic role.
Stomach Neoplasms
lncRNA GCAWKR Promotes Gastric Cancer Development by Scaffolding the Chromatin Modification Factors WDR5 and KAT2A.
Stomach Neoplasms
LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern.
Stomach Neoplasms
MicroRNA-4513 Promotes Gastric Cancer Cell Proliferation and Epithelial-Mesenchymal Transition Through Targeting KAT6B.
Stomach Neoplasms
NAT2 polymorphism in Omani gastric cancer patients-risk predisposition and clinicopathological associations.
Stomach Neoplasms
Nuclear Localization Is Not Required for Tip60 Tumor Suppressor Activity in Breast and Lung Cancer Cells.
Stomach Neoplasms
Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms.
Stomach Neoplasms
Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 gene point mutations in Japanese patients with gastric cancer.
Stomach Neoplasms
The p300/CBP associated factor: is frequently downregulated in intestinal-type gastric carcinoma and constitutes a biomarker for clinical outcome.
Stomach Neoplasms
[Glutathione S-transferases (GSTM1, GSTT1 and GSTP1) and N-acetyltransferase 2 polymorphisms and the risk of gastric cancer]
Stomatitis
A scoring system for the assessment of oral mucositis in daily nursing practice.
Stroke
A rhythm method for better health. Being aware of your body clock could help protect you from a heart attack or stroke and let you time your medications for when they'll do the most good.
Stroke
Abrupt shift of the pattern of diurnal variation in stroke onset with daylight saving time transitions.
Stroke
Acute stroke thrombolysis: time to dispense with the clock and move to tissue-based decision making?
Stroke
Benefit of thrombolysis for stroke is maintained around the clock: results from the SITS-EAST Registry.
Stroke
Circadian variation of blood pressure and the vascular response to asynchronous stress.
Stroke
Clinical usefulness of the clock drawing test applying rasch analysis in predicting of cognitive impairment.
Stroke
Clock drawing from the occupational therapy adult perceptual screening test: its correlation with demographic and clinical factors in the stroke population.
Stroke
Clock Drawing Performance Slows for Older Adults After Total Knee Replacement Surgery.
Stroke
Clock drawing task, mini-mental state examination and cognitive-functional independence measure: relation to functional outcome of stroke patients.
Stroke
Clock Drawing Test in acute stroke and its relationship with long-term functional and cognitive outcomes.
Stroke
CLOCK gene variation is associated with incidence of type-2 diabetes and cardiovascular diseases in type-2 diabetic subjects: dietary modulation in the PREDIMED randomized trial.
Stroke
Cognitive and connectome properties detectable through individual differences in graphomotor organization.
Stroke
Daylight saving time and the incidence of thrombolysis to treat acute ischemic stroke.
Stroke
Detecting delirium in patients with acute stroke: a systematic review of test accuracy.
Stroke
Diabetes and cognitive outcomes in a nationally representative sample: the National Health and Aging Trends Study.
Stroke
Discovery and Longitudinal Evaluation of Candidate Biomarkers for Ischaemic Stroke by Mass Spectrometry-Based Proteomics.
Stroke
Disruptions of Circadian Rhythms and Thrombolytic Therapy During Ischemic Stroke Intervention.
Stroke
Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke?
Stroke
Effect of Electroacupuncture on Neurological Deficit and Activity of Clock and Bmal1 in Cerebral Ischemic Rats.
Stroke
Effect of hyperlipidemia on the expression of circadian genes in apolipoprotein E knock-out atherosclerotic mice.
Stroke
Effects of a Feedback-Demanding Stroke Clock on Acute Stroke Management: A Randomized Study.
Stroke
Epigenetic Alterations Induced by Photothrombotic Stroke in the Rat Cerebral Cortex: Deacetylation of Histone h3, Upregulation of Histone Deacetylases and Histone Acetyltransferases.
Stroke
Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack.
Stroke
Identification of 20 novel loci associated with ischaemic stroke. Epigenome-wide association study.
Stroke
Implications of Circadian Rhythm in Stroke Occurrence: Certainties and Possibilities.
Stroke
Increase of Cry 1 expression is a common phenomenon of the disturbed circadian clock in ischemic stroke and opioid addiction.
Stroke
Increased Diagnostic Accuracy of Digital vs. Conventional Clock Drawing Test for Discrimination of Patients in the Early Course of Alzheimer's Disease from Cognitively Healthy Individuals.
Stroke
Long-term health-related quality of life after decompressive hemicraniectomy in stroke patients with life-threatening space-occupying brain edema.
Stroke
Measurement properties of the CLOX Executive Clock Drawing Task in an inpatient stroke rehabilitation setting.
Stroke
Multidirectional transpositions suggesting pathologic approach behavior after frontal stroke.
Stroke
Normative References for Graphomotor and Latency Digital Clock Drawing Metrics for Adults Age 55 and Older: Operationalizing the Production of a Normal Appearing Clock.
Stroke
Off-hour admission and impact on neurological outcome in endovascular treatment for acute ischemic stroke.
Stroke
Parkinson's Disease Cognitive Phenotypes Show Unique Clock Drawing Features when Measured with Digital Technology.
Stroke
Particulate Air Pollution, Clock Gene Methylation, and Stroke: Effects on Stroke Severity and Disability.
Stroke
Pathophysiology of ischaemic stroke: insights from imaging, and implications for therapy and drug discovery.
Stroke
Patterns of Admission and Outcomes for Patients with Intracranial Hemorrhage in Catalonia, Spain.
Stroke
Quantitative and qualitative performance of stroke versus normal elderly on six clock drawing systems.
Stroke
Reciprocal Control of the Circadian Clock and Cellular Redox State - a Critical Appraisal.
Stroke
Rhythm changes of clock genes, apoptosis-related genes and atherosclerosis-related genes in apolipoprotein E knockout mice.
Stroke
Screening for cognitive deficits after stroke: a comparison of three screening tools.
Stroke
Strokes happen round the clock, but why is stroke care worse on weekends and overnight?
Stroke
The Clock Drawing Test as a predictor of cognitive decline in non-demented stroke patients.
Stroke
The Expression and Localization of Histone Acetyltransferases HAT1 and PCAF in Neurons and Astrocytes of the Photothrombotic Stroke-Induced Penumbra in the Rat Brain Cortex.
Stroke
The Standardization of the Clock Drawing Test (CDT) for People with Stroke Using Rasch Analysis.
Stroke
Therapeutic Nuclear Magnetic Resonance affects the core clock mechanism and associated Hypoxia-inducible factor-1.
Stroke
Thrombolysis beyond the guidelines: two treatments in one subject within 90 hours based on a modified magnetic resonance imaging brain clock concept.
Stroke
[THE RELATIONSHIP BETWEEN SERUM AND LIQUOR IL-1?, IL-6, TNF?, IL-10 LEVELS AND CLINICAL, COGNITIVE AND FUNCTIONAL CHARACTERISTICS IN ACUTE ISCHEMIC STROKE].
Stroke
[Transient ischemic attacks and prolonged reversible ischemic neurologic deficit. Diagnosis, differential diagnosis and treatment]
Sudden Unexpected Death in Epilepsy
Altered circadian rhythms and oscillation of clock genes and sirtuin 1 in a model of sudden unexpected death in epilepsy.
Sudden Unexpected Death in Epilepsy
Sudden unexpected death in epilepsy: Trying to reset the clock on diabetes.
Supranuclear Palsy, Progressive
A study of five candidate genes in Parkinson's disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism.
Syncope
Auditory stimuli as a major cause of syncope in a patient with idiopathic long QT syndrome.
Syndactyly
Mosaic CREBBP mutation causes overlapping clinical features of Rubinstein-Taybi and Filippi syndromes.
Synovitis
Impaired Tip60-mediated Foxp3 acetylation attenuates regulatory T cell development in rheumatoid arthritis.
Synucleinopathies
Circadian rhythms of melatonin and peripheral clock gene expression in idiopathic REM sleep behavior disorder.
Tachycardia
The image of the heart and the synergic principle in psychoanalysis (psychosynergy). II. Three dreams of the disguised heart-image. III. The disguised image of the heart in a case of severe sexual impotence and talent inhibition; the case of the clock chimer (paroxysmal auricular tachycardia in father and son).
Tachycardia, Ventricular
Non-invasive prediction of ST elevation myocardial infarction complications by left ventricular Tei index.
Tachycardia, Ventricular
RyR2R420Q catecholaminergic polymorphic ventricular tachycardia mutation induces bradycardia by disturbing the coupled clock pacemaker mechanism.
Tauopathies
Drosophila spaghetti and doubletime link the circadian clock and light to caspases, apoptosis and tauopathy.
Tauopathies
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
Telangiectasis
Bevacizumab for Coats' disease with exudative retinal detachment and risk of vitreoretinal traction.
Telangiectasis
Chromatin acetylation, ?-amyloid precursor protein and its binding partner FE65 in DNA double strand break repair.
Telangiectasis
Clinical features and prognostic factors in 71 eyes over 20 years from patients with Coats' disease in Korea.
Telangiectasis
Factors Predictive of Subretinal Fluid Resolution in Coats Disease: Analysis of 177 Eyes in 177 Patients at a Single Center.
Telangiectasis
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.
Telangiectasis
Predictors of enucleation in Coats disease: analysis of 259 eyes of 259 patients at a single center.
Teratoma
Role of circadian gene Clock during differentiation of mouse pluripotent stem cells.
Testicular Neoplasms
Clock genes and cancer development in particular in endocrine tissues.
Tetanus
Blocking synaptic transmission with tetanus toxin light chain reveals modes of neurotransmission in the PDF-positive circadian clock neurons of Drosophila melanogaster.
Tetralogy of Fallot
The expanding phenotypes of cohesinopathies: one ring to rule them all!
Tetralogy of Fallot
[Histone acetylation and expression of acetylation-related enzymes in children with tetralogy of Fallot].
Thiamine Deficiency
Altered circadian rhythmicity is an early sign of murine dietary thiamine deficiency.
Thrombosis
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease.
Thrombosis
Circadian rhythms and the molecular clock in cardiovascular biology and disease.
Thrombosis
Downregulation of Clock in circulatory system leads to an enhancement of fibrinolysis in mice.
Thrombosis
Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients.
Thyroid Cancer, Papillary
Circadian clock characteristics are altered in human thyroid malignant nodules.
Thyroid Cancer, Papillary
CITED1 contributes to the progression of papillary thyroid carcinoma via the Wnt/?-catenin signaling pathway.
Thyroid Cancer, Papillary
Identification of new biomarkers for human papillary thyroid carcinoma employing NanoString analysis.
Thyroid Diseases
Analysis of expression of different histone deacetylases in autoimmune thyroid disease.
Thyroid Neoplasms
Bexarotene via CBP/p300 induces suppression of NF-?B-dependent cell growth and invasion in thyroid cancer.
Thyroid Neoplasms
Circadian clock characteristics are altered in human thyroid malignant nodules.
Thyroid Neoplasms
Effect of the Interaction Between Cadmium Exposure and CLOCK Gene Polymorphisms on Thyroid Cancer: a Case-Control Study in China.
Thyroid Neoplasms
Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.
Thyroid Neoplasms
PFKFB4 negatively regulated the expression of histone acetyltransferase GCN5 to mediate the tumorigenesis of thyroid cancer.
Thyroid Neoplasms
Role of the N-acetyltransferase 2 detoxification system in thyroid cancer susceptibility.
Thyroid Neoplasms
Synergistic cytotoxicity of BIIB021 with triptolide through suppression of PI3K/Akt/mTOR and NF-?B signal pathways in thyroid carcinoma cells.
Thyroid Neoplasms
The search for preoperative biomarkers for thyroid carcinoma: application of the thyroid circadian clock properties.
Thyroid Nodule
Circadian clock characteristics are altered in human thyroid malignant nodules.
Thyroiditis
Clock gene PERIOD3 polymorphism is associated with susceptibility to Graves' disease but not to Hashimoto's thyroiditis.
Tinnitus
Identification of a Circadian Clock in the Inferior Colliculus and Its Dysregulation by Noise Exposure.
Tongue Neoplasms
Alterations of 63 hub genes during lingual carcinogenesis in C57BL/6J mice.
Tongue Neoplasms
Identification of genes associated with tongue cancer in patients with a history of tobacco and/or alcohol use.
Tremor
Abnormal sense of intention preceding voluntary movement in patients with psychogenic tremor.
Triple Negative Breast Neoplasms
3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
ASMT Regulates Tumor Metastasis Through the Circadian Clock System in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Digging Deeper into Breast Cancer Epigenetics: Insights from Chemical Inhibition of Histone Acetyltransferase TIP60 In Vitro.
Triple Negative Breast Neoplasms
EP300 knockdown reduces cancer stem cell phenotype, tumor growth and metastasis in triple negative breast cancer.
Triple Negative Breast Neoplasms
Genetic events in the progression of adenoid cystic carcinoma of the breast to high-grade triple-negative breast cancer.
Triple Negative Breast Neoplasms
HMGA1 Modulates Gene Transcription Sustaining a Tumor Signalling Pathway Acting on the Epigenetic Status of Triple-Negative Breast Cancer Cells.
Triple Negative Breast Neoplasms
KAT6A Acetylation of SMAD3 Regulates Myeloid-Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple-Negative Breast Cancer.
Triple Negative Breast Neoplasms
Somatic EP300-G211S mutations are associated with overall somatic mutational patterns and breast cancer specific survival in triple-negative breast cancer.
Triple Negative Breast Neoplasms
Time will tell: Circadian clock dysregulation in triple negative breast cancer.
Trypanosomiasis
Dysregulation of photic induction of Fos-related protein in the biological clock during experimental trypanosomiasis.
Trypanosomiasis
Sleep and timekeeping changes, and dysregulation of the biological clock in experimental trypanosomiasis.
Trypanosomiasis, African
Altered neuronal activity rhythm and glutamate receptor expression in the suprachiasmatic nuclei of Trypanosoma brucei-infected rats.
Tuberculoma
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Tuberculosis
A Semi-Mechanistic Model of the Bactericidal Activity of High-Dose Isoniazid Against Multi-Drug-Resistant Tuberculosis: Results from a Randomized Clinical Trial.
Tuberculosis
Allele frequencies for glutathione S-transferase and N-acetyltransferase 2 differ in African population groups and may be associated with oesophageal cancer or tuberculosis incidence.
Tuberculosis
Correlation of N-acetyltransferase 2 genotype with isoniazid acetylation in Polish tuberculosis patients.
Tuberculosis
Crystal structure of l-glutamate N-acetyltransferase ArgA from Mycobacterium tuberculosis.
Tuberculosis
Determination of N-acetylation phenotyping in a Greek population using caffeine as a metabolic probe.
Tuberculosis
Development of a limited sampling strategy for the estimation of isoniazid exposure considering N-acetyltransferase 2 genotypes in Korean patients with tuberculosis.
Tuberculosis
Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients.
Tuberculosis
Epigenetic reader BRD4 supports mycobacterial pathogenesis by co-modulating host lipophagy and angiogenesis.
Tuberculosis
Genetic characterization of N-acetyltransferase 2 variants in acquired multidrug-resistant tuberculosis in Indonesia.
Tuberculosis
Hypothetical protein Rv3423.1 of Mycobacterium tuberculosis is a histone acetyltransferase.
Tuberculosis
Inferring patient to patient transmission of Mycobacterium tuberculosis from whole genome sequencing data.
Tuberculosis
Mycobacterium tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1.
Tuberculosis
N-acetyltransferase and cytochrome P450 2E1 gene polymorphisms and susceptibility to antituberculosis drug hepatotoxicity in an Indian population.
Tuberculosis
N-acetyltransferase gene polymorphisms & plasma isoniazid concentrations in patients with tuberculosis.
Tuberculosis
N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis.
Tuberculosis
NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis.
Tuberculosis
Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatotoxicity in Tunisian patients with tuberculosis.
Tuberculosis
Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity.
Tuberculosis
Polymorphisms of N-acetyltransferase 2, glutathione S-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis.
Tuberculosis
Sequence and structural characterization of tbnat gene in isoniazid-resistant Mycobacterium tuberculosis: identification of new mutations.
Tuberculosis
Turkish and Japanese Mycobacterium tuberculosis sublineages share a remote common ancestor.
Tuberculosis
World Tuberculosis Day 2021 Theme - 'The Clock is Ticking' - and the world is running out of time to deliver the United Nations General Assembly commitments to End TB due to the COVID-19 pandemic.
Tuberculosis
[The associations of polymorphism of N-acetyltransferase 2 gene is associated with antituberculosis drug-induced hepatotoxicity in tuberculosis patients.]
Tuberculosis, Meningeal
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
Tuberculosis, Multidrug-Resistant
Genetic characterization of N-acetyltransferase 2 variants in acquired multidrug-resistant tuberculosis in Indonesia.
Tuberculosis, Pulmonary
N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in patients with drug-resistant pulmonary tuberculosis.
Tuberculosis, Pulmonary
NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis.
Tuberculosis, Pulmonary
NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy.
Tuberculosis, Pulmonary
The effects of SP110's associated genes on fresh cavitary pulmonary tuberculosis in Han Chinese population.
Tuberous Sclerosis
The Circadian Protein Period2 Suppresses mTORC1 Activity via Recruiting Tsc1 to mTORC1 Complex.
Uremia
A molecular circadian clock operates in the parathyroid gland and is disturbed in chronic kidney disease associated bone and mineral disorder.
Ureteral Obstruction
Circadian CLOCK Mediates Activation of Transforming Growth Factor-? Signaling and Renal Fibrosis through Cyclooxygenase 2.
Urinary Bladder Neck Obstruction
New modification of transurethral incision of the prostate in surgical treatment of bladder outlet obstruction: prospective study.
Urinary Bladder Neoplasms
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking.
Urinary Bladder Neoplasms
Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies.
Urinary Bladder Neoplasms
Association between N-Acetyltransferase 2 Polymorphism and Bladder Cancer Risk: a Meta-Analysis in a Single Ethnic Group.
Urinary Bladder Neoplasms
Association Between N-acetyltransferase 2 Polymorphism and Bladder Cancer Risk: Results From Studies of the Past Decade and a Meta-Analysis.
Urinary Bladder Neoplasms
Association of genotypes of carcinogen-metabolizing enzymes and smoking status with bladder cancer in a Japanese population.
Urinary Bladder Neoplasms
Association of N-acetyltransferase 1 polymorphism and bladder cancer risk: an updated meta-analysis and trial sequential analysis.
Urinary Bladder Neoplasms
Association of NAT2, GSTM1, GSTT1, CYP2A6, and CYP2A13 gene polymorphisms with susceptibility and clinicopathologic characteristics of bladder cancer in Central China.
Urinary Bladder Neoplasms
Bayesian synthesis of epidemiological evidence with different combinations of exposure groups: application to a gene-gene-environment interaction.
Urinary Bladder Neoplasms
Bladder cancer risk from the perspective of genetic polymorphisms in the carcinogen metabolizing enzymes.
Urinary Bladder Neoplasms
Cigarette smoking, N-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction.
Urinary Bladder Neoplasms
Circadian clock protein CRY1 prevents paclitaxel?induced senescence of bladder cancer cells by promoting p53 degradation.
Urinary Bladder Neoplasms
Correlation between N-acetyltransferase activity and NAT2 genotype in Chinese males.
Urinary Bladder Neoplasms
Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility--a review.
Urinary Bladder Neoplasms
Differential association for N-acetyltransferase 2 genotype and phenotype with bladder cancer risk in Chinese population.
Urinary Bladder Neoplasms
Distribution and Role of N-acetyltransferase 2 Genetic Polymorphisms in Bladder Cancer Risk in a Lebanese Population
Urinary Bladder Neoplasms
Double primary cancers of the prostate and bladder: a literature review.
Urinary Bladder Neoplasms
Effect of NAT2 gene polymorphism on bladder cancer risk in Slovak population.
Urinary Bladder Neoplasms
Ellagic [correction of ellagica] acid inhibits arylamine N-acetyltransferase activity and DNA adduct formation in human bladder tumor cell lines (T24 and TSGH 8301).
Urinary Bladder Neoplasms
Ellagica acid inhibits arylamine N-acetyltransferase activity and DNA adduct formation in human bladder tumor cell lines (T24 and TSGH 8301).
Urinary Bladder Neoplasms
EP300 mutation is associated with tumor mutation burden and promotes antitumor immunity in bladder cancer patients.
Urinary Bladder Neoplasms
Expression of TIP60 (tat-interactive protein) and MRE11 (meiotic recombination 11 homolog) predict treatment-specific outcome of localised invasive bladder cancer.
Urinary Bladder Neoplasms
Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer.
Urinary Bladder Neoplasms
Genetic polymorphisms of N-acetyltransferase 1 and 2 and risk of cigarette smoking-related bladder cancer.
Urinary Bladder Neoplasms
Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype.
Urinary Bladder Neoplasms
Genotyping of the polymorphic N-acetyltransferase (NAT2) and loss of heterozygosity in bladder cancer patients.
Urinary Bladder Neoplasms
HBO1 promotes cell proliferation in bladder cancer via activation of Wnt/?-catenin signaling.
Urinary Bladder Neoplasms
Highlight report: N-acetyltransferase 2 and urinary bladder cancer risk.
Urinary Bladder Neoplasms
Immunochemical detection of arylamine N-acetyltransferase in normal and neoplastic bladder.
Urinary Bladder Neoplasms
Immunohistochemical analysis of human arrest-defective-1 expressed in cancers in vivo.
Urinary Bladder Neoplasms
Impact of misclassification in genotype-exposure interaction studies: example of N-acetyltransferase 2 (NAT2), smoking, and bladder cancer.
Urinary Bladder Neoplasms
Influence Networks Compared with Reaction Networks: Semantics, Expressivity and Attractors.
Urinary Bladder Neoplasms
Interaction effect in bladder cancer between N-acetyltransferase 2 genotype and alcohol drinking.
Urinary Bladder Neoplasms
Luteolin induces N-acetylation and DNA adduct of 2-aminofluorene accompanying N-acetyltransferase activity and gene expression in human bladder cancer T24 cell line.
Urinary Bladder Neoplasms
Modifying Effect of Smoking on GSTM1 and NAT2 in Relation to the Risk of Bladder Cancer in Mongolian Population: A Case-Control Study.
Urinary Bladder Neoplasms
N-Acetyltransferase 1 (NAT1) Genotype: A Risk Factor for Urinary Bladder Cancer in a Lebanese Population.
Urinary Bladder Neoplasms
N-acetyltransferase 1 polymorphism and bladder cancer susceptibility: a meta-analysis of epidemiological studies.
Urinary Bladder Neoplasms
N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction.
Urinary Bladder Neoplasms
N-acetyltransferase 2 gene polymorphism as a biomarker for susceptibility to bladder cancer in Bangladeshi population.
Urinary Bladder Neoplasms
N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk.
Urinary Bladder Neoplasms
N-Acetyltransferase 2 genotype, exfoliated urothelial cells and benzidine exposure.
Urinary Bladder Neoplasms
N-acetyltransferase 2 phenotype in painters with bladder cancer and controls.
Urinary Bladder Neoplasms
N-acetyltransferase 2 polymorphism is associated with bladder cancer risk: An updated meta-analysis based on 54 case-control studies.
Urinary Bladder Neoplasms
N-acetyltransferase 2 polymorphisms, tobacco smoking, and breast cancer risk in the breast and prostate cancer cohort consortium.
Urinary Bladder Neoplasms
N-acetyltransferase activity in the urine in Japanese subjects: comparison in healthy persons and bladder cancer patients.
Urinary Bladder Neoplasms
N-acetyltransferase activity is involved in paclitaxel-induced N-acetylation of 2-aminofluorene in human bladder cancer cells (T24).
Urinary Bladder Neoplasms
N-acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark.
Urinary Bladder Neoplasms
N-acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark. Environmental Health Perspectives;1979:71-79.
Urinary Bladder Neoplasms
N-acetyltransferase phenotypes in bladder tumour patients with and without carcinoma in situ in selected site biopsies.
Urinary Bladder Neoplasms
N-acetyltransferase phenotypes of bladder cancer patients in a low-risk population.
Urinary Bladder Neoplasms
NAT1 genotypic and phenotypic contribution to urinary bladder cancer risk: a systematic review and meta-analysis.
Urinary Bladder Neoplasms
NAT2 acetylator phenotype, occupation and bladder cancer risk: Results from the EPIC cohort.
Urinary Bladder Neoplasms
Occupational bladder cancer: Polymorphisms of xenobiotic metabolizing enzymes, exposures, and prognosis.
Urinary Bladder Neoplasms
p21 and CK2 interaction-mediated HDAC2 phosphorylation modulates KLF4 acetylation to regulate bladder cancer cell proliferation.
Urinary Bladder Neoplasms
p300 mediates cellular resistance to doxorubicin in bladder cancer.
Urinary Bladder Neoplasms
p53 mutations in bladder cancer: evidence for exogenous versus endogenous risk factors.
Urinary Bladder Neoplasms
Polymorphic enzymes, urinary bladder cancer risk, and structural change in the local industry.
Urinary Bladder Neoplasms
Polymorphism in the N-acetyltransferase 1 alleles NAT1*10 and NAT1*14A and cytological gradings of exfoliated urothelial cells in benzidine-exposed Chinese workers: discussion of ethnic differences.
Urinary Bladder Neoplasms
Polymorphism of N-acetyltransferase 2 (NAT2) gene polymorphism in shanghai population: occupational and non-occupational bladder cancer patient groups.
Urinary Bladder Neoplasms
Polymorphisms of N-acetyltransferase 2, glutathione S-transferase mu and theta genes as risk factors of bladder cancer in relation to asthma and tuberculosis.
Urinary Bladder Neoplasms
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility.
Urinary Bladder Neoplasms
Polymorphisms of xenobiotic metabolizing enzymes in bladder cancer patients of the Semmelweis University Budapest, Hungary.
Urinary Bladder Neoplasms
Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias.
Urinary Bladder Neoplasms
Prognostic Significance of CREB-Binding Protein and CD81 Expression in Primary High Grade Non-Muscle Invasive Bladder Cancer: Identification of Novel Biomarkers for Bladder Cancer Using Antibody Microarray.
Urinary Bladder Neoplasms
Refinement of the prediction of N-acetyltransferase 2 (NAT2) phenotypes with respect to enzyme activity and urinary bladder cancer risk.
Urinary Bladder Neoplasms
Revisiting Histone Deacetylases in Human Tumorigenesis: The Paradigm of Urothelial Bladder Cancer.
Urinary Bladder Neoplasms
Risks on N-acetyltransferase 2 and bladder cancer: a meta-analysis.
Urinary Bladder Neoplasms
Role of N-acetyltransferase phenotype in human susceptibility to bladder carcinogenic arylamines.
Urinary Bladder Neoplasms
Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer.
Urinary Bladder Neoplasms
rs1495741 as a tag single nucleotide polymorphism of N-acetyltransferase 2 acetylator phenotype associates bladder cancer risk and interacts with smoking: A systematic review and meta-analysis.
Urinary Bladder Neoplasms
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.
Urinary Bladder Neoplasms
Scientific and ethical aspects of genetic screening of workers for cancer risk: the case of the N-acetyltransferase phenotype.
Urinary Bladder Neoplasms
Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.
Urinary Bladder Neoplasms
The ability to 4-hydroxylate debrisoquine is related to recurrence of bladder cancer.
Urinary Bladder Neoplasms
The inhibition of N-acetyltransferase activity and gene expression in human bladder cancer cells (T24) by shikonin.
Urinary Bladder Neoplasms
The role of genetically-based metabolic polymorphisms in human cancer: an ecological study of bladder cancer and N-acetyltransferase in 23 populations.
Urinary Bladder Neoplasms
Tobacco use and occupational exposure to carcinogens, but not N-acetyltransferase 2 genotypes are major risk factors for bladder cancer in the Japanese.
Urinary Bladder Neoplasms
Ultra-slow N-Acetyltransferase 2 Is Associated with Recurrence-free Time in Bladder Cancer Patients.
Urinary Bladder Neoplasms
Urinary bladder cancer risk factors in an area of former coal, iron, and steel industries in Germany.
Urinary Bladder Neoplasms
[Determination of the N-acetyltransferase phenotype in urothelial cancer patients and healthy controls]
Urinary Bladder Neoplasms
[Significance of N-acetyltransferase phenotype in development of bladder neoplasms]
Urinary Incontinence
Caring for stroke survivors: baseline and 1-year determinants of caregiver burden.
Urinary Tract Infections
Antibiotic Treatment for Febrile Urinary Tract Infection: The Clock Is Ticking.
Urologic Diseases
Polymorphic enzymes, urinary bladder cancer risk, and structural change in the local industry.
Uterine Cervical Neoplasms
Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells.
Uterine Cervical Neoplasms
E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60.
Uterine Cervical Neoplasms
Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.
Uterine Cervical Neoplasms
Knockdown of MIR9?3HG inhibits proliferation and promotes apoptosis of cervical cancer cells by miR?498 via EP300.
Uterine Cervical Neoplasms
Lysine Acetyltransferase 2B predicts favorable prognosis and functions as anti-oncogene in cervical carcinoma.
Uterine Cervical Neoplasms
N-acetyltransferase 2 gene polymorphism in patients with cervical cancer.
Uterine Cervical Neoplasms
N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski).
Uterine Cervical Neoplasms
Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective.
Uterine Cervical Neoplasms
Swelling-activated taurine and K+ transport in human cervical cancer cells: association with cell cycle progression.
Uterine Cervical Neoplasms
Tip60 and p300 function antagonistically in the epigenetic regulation of HPV18 E6/E7 genes in cervical cancer HeLa cells.
Varicose Veins
Upregulation of the gene expression of CLOCK is correlated with hypoxia-inducible factor 1? in advanced varicose lesions.
Vascular Calcification
Setting the clock back: new hope for dialysis patients. Sodium thiosulphate and the regression of vascular calcifications.
Vascular Diseases
CLOCK Promotes Endothelial Damage by Inducing Autophagy through Reactive Oxygen Species.
Vascular Diseases
The executive clock drawing task (CLOX) is a poor screening test for executive dysfunction in Chinese elderly patients with subcortical ischemic vascular disease.
Vascular Diseases
Time microscopy of circadian expression of cardiac clock gene mRNA transcription: chronodiagnostic and chrono-therapeutic implications.
Vascular Headaches
Cluster headache: evidence for a disorder of circadian rhythm and hypothalamic function.
Venous Thromboembolism
Circadian variation within hemostasis: an underrecognized link between biology and disease?
Vesicular Stomatitis
Punctuated equilibrium and positive Darwinian evolution in vesicular stomatitis virus.
Virus Diseases
A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor alpha gene expression.
Virus Diseases
A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients.
Virus Diseases
C646, a Novel p300/CREB-Binding Protein-Specific Inhibitor of Histone Acetyltransferase, Attenuates Influenza A Virus Infection.
Virus Diseases
Cell autonomous regulation of herpes and influenza virus infection by the circadian clock.
Virus Diseases
Circadian Clock-Coupled Lung Cellular and Molecular Functions in Chronic Airway Diseases.
Virus Diseases
Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection.
Virus Diseases
Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.
Virus Diseases
Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription.
Virus Diseases
Human papillomavirus and the landscape of secondary genetic alterations in oral cancers.
Virus Diseases
Inducer-specific enhanceosome formation controls tumor necrosis factor alpha gene expression in T lymphocytes.
Virus Diseases
N-Acetyltransferase-2, glutathione S-transferase M1 and T1 genetic polymorphisms, cigarette smoking and hepatocellular carcinoma: a case-control study.
Virus Diseases
Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling.
Virus Diseases
Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus.
Virus Diseases
The Circadian Clock, the Immune System, and Viral Infections: The Intricate Relationship Between Biological Time and Host-Virus Interaction.
Virus Diseases
The Involvement of Histone H3 Acetylation in Bovine Herpesvirus 1 Replication in MDBK Cells.
Virus Diseases
TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.
Virus Diseases
Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation.
Vision Disorders
Combination of capsular tension ring and capsular tension segment for the management of lens coloboma >4 clock hours.
Vitamin A Deficiency
Circadian expression of clock genes is maintained in the liver of Vitamin A-deficient mice.
Vitamin A Deficiency
Circadian rhythms of locomotor activity and hippocampal clock genes expression are dampened in vitamin A-deficient rats.
Vitamin A Deficiency
Retinoic acid receptors move in time with the clock in the hippocampus. Effect of a vitamin-A-deficient diet.
Vitamin A Deficiency
Temporal patterns of lipoperoxidation and antioxidant enzymes are modified in the hippocampus of vitamin A-deficient rats.
Vitreoretinopathy, Proliferative
Pneumatic retinopexy. A multicenter randomized controlled clinical trial comparing pneumatic retinopexy with scleral buckling. The Retinal Detachment Study Group.
Vitreoretinopathy, Proliferative
Pneumatic retinopexy. A two-step outpatient operation without conjunctival incision.
Vitreoretinopathy, Proliferative
Pneumatic retinopexy: a survey of current practice patterns among the vitreous society members.
Vitreoretinopathy, Proliferative
Surgical outcome and risk stratification for primary retinal detachment repair: results from the Scottish Retinal Detachment study.
Vitreoretinopathy, Proliferative
The treatment of bullous rhegmatogenous retinal detachment.
Vitreoretinopathy, Proliferative
TRAUMATIC RETINAL DETACHMENT CAUSED BY NERF GUN SHOT IN A PEDIATRIC PATIENT.
Vitreous Detachment
[Giant retinal tears treated with lens sparing, bimanual 23 g vitrectomy without scleral buckle].
Vitreous Hemorrhage
Effects of Early Treatment of Retinopathy of Prematurity at a Tertiary Care Hospital in Saudi Arabia: A Retrospective Study.
Vitreous Hemorrhage
Pneumatic retinopexy: a survey of current practice patterns among the vitreous society members.
Whooping Cough
Biosynthesis of a rare di-N-acetylated sugar in the lipopolysaccharides of both Pseudomonas aeruginosa and Bordetella pertussis occurs via an identical scheme despite different gene clusters.
Whooping Cough
Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines.
Whooping Cough
The melatonin receptor MT1 is required for the differential regulatory actions of melatonin on neuronal 'clock' gene expression in striatal neurons in vitro.
Whooping Cough
Whole-genome sequencing reveals the effect of vaccination on the evolution of Bordetella pertussis.
Wilms Tumor
Reversible histone acetylation involved in transcriptional regulation of WT1 gene.
Xeroderma Pigmentosum
From xeroderma pigmentosum to the biological clock contributions of Dirk Bootsma to human genetics.
Xeroderma Pigmentosum
Impact of Occupational Exposures and Genetic Polymorphisms on Recurrence and Progression of Non-Muscle-Invasive Bladder Cancer.
Xeroderma Pigmentosum
Impact of the Circadian Clock on UV-Induced DNA Damage Response and Photocarcinogenesis.
Yellow Fever
Cloning and daily expression of the timeless gene in Aedes aegypti (Diptera:Culicidae).
Yellow Fever
CREB-binding protein regulates metamorphosis and compound eye development in the yellow fever mosquito, Aedes aegypti.
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
evolution
O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9
the enzyme belongs to the nuclear receptors coactivators
physiological function
O15516, O95251, P21675, Q15788, Q8WYB5, Q92793, Q92794, Q92830, Q92831, Q92993, Q9BQG0, Q9H7Z6, Q9H9T3, Q9UKN8, Q9Y6Q9
lysine acetylation is a post-translational modification of both histone and nonhistone proteins that is catalyzed by lysine acetyltransferases and plays a key role in numerous biological contexts
additional information
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
additional information
-
mechanism of action and structural analysis of KATs, detailed overview. All KATs are characterized by a similar tertiary structure in the central core. This structure consists of an alpha/beta fold, which is important for co-substrate binding and catalysis
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fiorentino, F.; Mai, A.; Rotili, D.
Lysine acetyltransferase inhibitors structure-activity relationships and potential therapeutic implications
Future Med. Chem.
10
1067-1091
2018
Drosophila melanogaster (O02193), Drosophila melanogaster (P51123), Drosophila melanogaster (Q960X4), Homo sapiens (O15516), Homo sapiens (O95251), Homo sapiens (P21675), Homo sapiens (Q15788), Homo sapiens (Q8WYB5), Homo sapiens (Q92793), Homo sapiens (Q92794), Homo sapiens (Q92830), Homo sapiens (Q92831), Homo sapiens (Q92993), Homo sapiens (Q9BQG0), Homo sapiens (Q9H7Z6), Homo sapiens (Q9H9T3), Homo sapiens (Q9UKN8), Homo sapiens (Q9Y6Q9), Homo sapiens, Saccharomyces cerevisiae (P39979), Saccharomyces cerevisiae (P46677), Saccharomyces cerevisiae (P53114), Saccharomyces cerevisiae (Q06592), Saccharomyces cerevisiae (Q07794), Saccharomyces cerevisiae ATCC 204508 (P39979), Saccharomyces cerevisiae ATCC 204508 (P46677), Saccharomyces cerevisiae ATCC 204508 (P53114), Saccharomyces cerevisiae ATCC 204508 (Q06592), Saccharomyces cerevisiae ATCC 204508 (Q07794)
brenda
EXTERNAL LINKS (specific for EC-Number 2.3.1.48)
Transporter Classification Database (TCDB): 1.I.1.1.3
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Release 2023.1 (January 2023)
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