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Information on EC 2.3.1.4 - glucosamine-phosphate N-acetyltransferase and Organism(s) Mus musculus and UniProt Accession Q9JK38

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This record set is specific for:
Mus musculus
UNIPROT: Q9JK38 not found.
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The taxonomic range for the selected organisms is: Mus musculus
The enzyme appears in selected viruses and cellular organisms
Synonyms
glucosamine-6-phosphate n-acetyltransferase, glucosamine 6-phosphate n-acetyltransferase, glucosamine-phosphate n-acetyltransferase, glucosamine-6-phosphate acetyltransferase, glucosamine-6-phosphate n-acetyltransferase 1, glcnac-6-phosphate n-acetyltransferase, glucosamine 6-phosphate acetylase, osgna1, hsgna1, scgna1, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
acetyltransferase, glucosamine phosphate
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-
-
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aminodeoxyglucosephosphate acetyltransferase
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-
-
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D-glucosamine-6-P N-acetyltransferase
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-
-
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glucosamine 6-phosphate acetylase
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glucosamine 6-phosphate N-acetyltransferase
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glucosamine phosphate acetyltransferase
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glucosamine-6-phosphate acetylase
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N-acetylglucosamine-6-phosphate synthase
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phosphoglucosamine acetylase
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-
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phosphoglucosamine N-acetylase
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phosphoglucosamine transacetylase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Acyl group transfer
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PATHWAY SOURCE
PATHWAYS
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-, -
SYSTEMATIC NAME
IUBMB Comments
acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
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CAS REGISTRY NUMBER
COMMENTARY hide
9031-91-8
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
acetyl-CoA + D-glucosamine 6-phosphate
CoA + N-acetyl-D-glucosamine 6-phosphate
show the reaction diagram
-
-
?
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.12
acetyl-CoA
recombinant enzyme
0.04
D-glucosamine 6-phosphate
recombinant enzyme
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
Uniprot
Manually annotated by BRENDA team
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
attached to cytoplasmic membrane leaflet of Golgi and other intracellular membranes
Manually annotated by BRENDA team
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
GNA1_MOUSE
184
0
20791
Swiss-Prot
other Location (Reliability: 2)
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
21000
x * 21000, SDS-PAGE, immunoblotting, deduced from nucleotide sequence
SUBUNIT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
x * 21000, SDS-PAGE, immunoblotting, deduced from nucleotide sequence
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-70°C, 6 months, several freeze/thaw cycles, no loss of activity
PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant His-tagged enzyme
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Sf9 insect cells and Escherichia coli
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Boehmelt, G.; Fialka, I.; Brothers, G.; McGinley, M.D.; Patterson, S.D.; Mo, R.; Hui, C.C.; Chung, S.; Huber, L.A.; Mak, T.W.; Iscove, N.N.
Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association
J. Biol. Chem.
275
12821-12832
2000
Mus musculus (Q9JK38), Mus musculus
Manually annotated by BRENDA team