Reference on EC 2.3.1.35 - glutamate N-acetyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Morris, C.J.; Thompson, J.F.
Acetyl coenzyme A-glutamate acetyltransferase and N2-acetylornithine-glutamate acetyltransferase of Chlorella
Plant Physiol.
55
960-967
1975
Chlorella vulgaris
Jain, J.C.; Shargool, P.D.
A modified assay system for enzymes involved in N-acetyl group transfer reactions: its use to study enzymes involved in ornithine biosynthesis in plants
Anal. Biochem.
138
25-29
1984
Pisum sativum
Staub, M.; Denes, G.
Mechanism of arginine biosynthesis in Chlamydomonas reinhardti. I. Purification and properties of ornithine acetyltransferase
Biochim. Biophys. Acta
128
82-91
1966
Chlamydomonas reinhardtii
Meile, L.; Leisinger, T.
Enzymes of arginine biosynthesis in methanogenic bacteria
Experientia
40
899-900
1984
Methanothermobacter thermautotrophicus, Methanobrevibacter arboriphilus, Methanococcus vannielii
-
Kershaw, N.J.; McNaughton, H.J.; Hewitson, K.S.; Hernandez, H.; Griffin, J.; Hughes, C.; Greaves, P.; Barton, B.; Robinson, C.V.; Schofield, C.J.
ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity
Eur. J. Biochem.
269
2052-2059
2002
Streptomyces clavuligerus
Liu, Y.; Van Heeswijck, R.; Hoj, P.; Hoogenraad, N.
Purification and characterization of ornithine acetyltransferase from Saccharomyces cerevisiae
Eur. J. Biochem.
228
291-296
1995
Saccharomyces cerevisiae
Marc, F.; Weigel, P.; Legrain, C.; Almeras, Y.; Santrot, M.; Glansdorff, N.; Sakanyan, V.
Characterization and kinetic mechanism of mono- and bifunctional ornithine acetyltransferases from thermophilic microorganisms
Eur. J. Biochem.
267
5217-5226
2000
Geobacillus stearothermophilus, Methanocaldococcus jannaschii, Thermotoga neapolitana
Crabeel, M.; Abadjieva, A.; Hilven, P.; Desimpelaere, J.; Soetens, O.
Characterization of the Saccharomyces cerevisiae ARG7 gene encoding ornithine acetyltransferase, an enzyme also endowed with acetylglutamate synthase activity
Eur. J. Biochem.
250
232-241
1997
Saccharomyces cerevisiae
Sakanyan, V.; Charlier, D.; Legrain, C.; Kochikyan, A.; Mett, I.; Pierard, A.; Glansdorff, N.
Primary structure, partial purification and regulation of key enzymes of the acetyl cycle of arginine biosynthesis in Bacillus stearothermophilus: dual function of ornithine acetyltransferase
J. Gen. Microbiol.
139
393-402
1993
Geobacillus stearothermophilus
Marc, F.; Weigel, P.; Legrain, C.; Glansdorff, N.; Sakanyan, V.
An invariant threonine is involved in self-catalyzed cleavage of the precursor protein for ornithine acetyltransferase
J. Biol. Chem.
276
25404-25410
2001
Geobacillus stearothermophilus
Abadjieva, A.; Hilven, P.; Pauwels, K.; Crabeel, M.
The yeast ARG7 gene product is autoproteolyzed to two subunit peptides, yielding active ornithine acetyltransferase
J. Biol. Chem.
275
11361-11367
2000
Saccharomyces cerevisiae
Elkins, J.M.; Kershaw, N.J.; Schofield, C.J.
X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster
Biochem. J.
385
565-573
2005
Streptomyces clavuligerus (P0DJQ5)
Cheng, H.; Grishin, N.V.
DOM-fold: a structure with crossing loops found in DmpA, ornithine acetyltransferase, and molybdenum cofactor-binding domain
Protein Sci.
14
1902-1910
2005
Streptomyces clavuligerus
Maes, D.; Crabeel, M.; Van De Weerdt, C.; Martial, J.; Peeters, E.; Charlier, D.; Decanniere, K.; Vanhee, C.; Wyns, L.; Zegers, I.
Crystallization of ornithine acetyltransferase from yeast by counter-diffusion and preliminary X-ray study
Acta Crystallogr. Sect. F
F62
1294-1297
2006
Saccharomyces cerevisiae
Takahara, K.; Akashi, K.; Yokota, A.
Purification and characterization of glutamate N-acetyltransferase involved in citrulline accumulation in wild watermelon
FEBS J.
272
5353-5364
2005
Citrullus lanatus
Haskins, N.; Panglao, M.; Qu, Q.; Majumdar, H.; Cabrera-Luque, J.; Morizono, H.; Tuchman, M.; Caldovic, L.
Inversion of allosteric effect of arginine on N-acetylglutamate synthase, a molecular marker for evolution of tetrapods
BMC Biochem.
9
24
2008
Mus musculus, Xanthomonas campestris
Sankaranarayanan, R.; Garen, C.R.; Cherney, M.M.; Yuan, M.; Lee, C.; James, M.N.
Preliminary X-ray crystallographic analysis of ornithine acetyltransferase (Rv1653) from Mycobacterium tuberculosis
Acta Crystallogr. Sect. F
65
173-176
2009
Mycobacterium tuberculosis (P9WPZ3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WPZ3)
Iqbal, A.; Clifton, I.J.; Bagonis, M.; Kershaw, N.J.; Domene, C.; Claridge, T.D.; Wharton, C.W.; Schofield, C.J.
Anatomy of a simple acyl intermediate in enzyme catalysis: combined biophysical and modeling studies on ornithine acetyl transferase
J. Am. Chem. Soc.
131
749-757
2009
Streptomyces clavuligerus (P0DJQ5)
Dou, W.; Xu, M.; Cai, D.; Zhang, X.; Rao, Z.; Xu, Z.
Improvement of L-arginine production by overexpression of a bifunctional ornithine acetyltransferase in Corynebacterium crenatum
Appl. Biochem. Biotechnol.
165
845-855
2011
Corynebacterium crenatum (C1KGU6), Corynebacterium crenatum
Sankaranarayanan, R.; Cherney, M.M.; Garen, C.; Garen, G.; Niu, C.; Yuan, M.; James, M.N.
The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor
J. Mol. Biol.
397
979-990
2010
Mycobacterium tuberculosis (P9WPZ3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WPZ3)
Iqbal, A.; Clifton, I.J.; Chowdhury, R.; Ivison, D.; Domene, C.; Schofield, C.J.
Structural and biochemical analyses reveal how ornithine acetyl transferase binds acidic and basic amino acid substrates
Org. Biomol. Chem.
9
6219-6225
2011
Streptomyces clavuligerus (P0DJQ5)
Van de Casteele, M.; Demarez, M.; Legrain, C.; Glansdorff, N.; Pierard, A.
Pathways of arginine biosynthesis in extreme thermophilic archaeo- and eubacteria
J. Gen. Microbiol.
136
1177-1183
1990
no activity in Sulfolobus solfataricus
-
Hao, N.; Mu, J.; Hu, N.; Xu, S.; Shen, P.; Yan, M.; Li, Y.; Xu, L.
Implication of ornithine acetyltransferase activity on L-ornithine production in Corynebacterium glutamicum
Biotechnol. Appl. Biochem.
63
15-21
2016
Corynebacterium glutamicum (Q59280), Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032 (Q59280)
Hao, N.; Mu, J.; Hu, N.; Xu, S.; Yan, M.; Li, Y.; Guo, K.; Xu, L.
Improvement of L-citrulline production in Corynebacterium glutamicum by ornithine acetyltransferase
J. Ind. Microbiol. Biotechnol.
42
307-313
2015
Corynebacterium glutamicum (Q59280), Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032 (Q59280), Corynebacterium glutamicum ATCC 13032
Hernandez, V.M.; Girard, L.; Hernandez-Lucas, I.; Vazquez, A.; Ortiz-Ortiz, C.; Diaz, R.; Dunn, M.F.
Genetic and biochemical characterization of arginine biosynthesis in Sinorhizobium meliloti 1021
Microbiology
161
1671-1682
2015
Sinorhizobium meliloti (Q92MJ1), Sinorhizobium meliloti
Hao, N.; Mu, J.; Hu, N.; Xu, S.; Shen, P.; Yan, M.; Li, Y.; Xu, L.
Implication of ornithine acetyltransferase activity on L-ornithine production in Corynebacterium glutamicum
Biotechnol. Appl. Biochem.
63
15-21
2016
Corynebacterium glutamicum (Q59280), Corynebacterium glutamicum, Corynebacterium glutamicum LMG 3730 (Q59280), Corynebacterium glutamicum ATCC 13032 (Q59280), Corynebacterium glutamicum JCM 1318 (Q59280), Corynebacterium glutamicum NCIMB 10025 (Q59280), Corynebacterium glutamicum DSM 20300 (Q59280)
Mishra, A.; Mamidi, A.S.; Rajmani, R.S.; Ray, A.; Roy, R.; Surolia, A.
An allosteric inhibitor of Mycobacterium tuberculosis ArgJ implications to a novel combinatorial therapy
EMBO Mol. Med.
10
e8038
2018
Mycobacterium tuberculosis (P9WPZ3), Mycobacterium tuberculosis H37Rv (P9WPZ3), Mycobacterium tuberculosis ATCC 25618 (P9WPZ3)
Shu, Q.; Xu, M.; Li, J.; Yang, T.; Zhang, X.; Xu, Z.; Rao, Z.
Improved L-ornithine production in Corynebacterium crenatum by introducing an artificial linear transacetylation pathway
J. Ind. Microbiol. Biotechnol.
45
393-404
2018
no activity in Escherichia coli, Corynebacterium crenatum (P62058), Corynebacterium crenatum, Corynebacterium crenatum SYPA5-5 (P62058)
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