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Information on EC 2.3.1.317 - 3-dehydrocarnitine:acetyl-CoA trimethylamine transferase

for references in articles please use BRENDA:EC2.3.1.317

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IUBMB Comments

The enzyme, characterized from Pseudomonas aeruginosa and other bacteria, belongs to a class of enzymes known as β-keto acid cleavage enzymes (BKACE). It participates in an L-carnitine degradation pathway. cf. EC 2.3.1.247, (5S)-5-amino-3-oxohexanoate:acetyl-CoA ethylamine transferase, EC 2.3.1.318, 3-oxoadipate:acetyl-CoA acetyltransferase, and EC 2.3.1.319, 3,5-dioxohexanoate:acetyl-CoA acetone transferase.

The enzyme appears in viruses and cellular organisms

Synonyms
3-dehydrocarnitine cleavage enzyme, beta-KACE, BKACE, CDHC, DUF849, PA5387, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-dehydrocarnitine + acetyl-CoA = acetoacetate + betainyl-CoA
show the reaction diagram
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Highest Expressing Human Cell Lines
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