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Information on EC 2.3.1.288 - 2-O-sulfo trehalose long-chain-acyltransferase

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IUBMB Comments
This mycobacterial enzyme catalyses the acylation of 2-O-sulfo-alpha,alpha-trehalose at the 2' position by a C16 or C18 fatty acyl group during the biosynthesis of mycobacterial sulfolipids.
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The expected taxonomic range for this enzyme is: Mycobacterium tuberculosis
Synonyms
papA2, Rv3820c, trehalose-2-sulfate acyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
palmitoyl-CoA + 2-O-sulfo-alpha,alpha-trehalose = 2-O-sulfo-2'-palmitoyl-alpha,alpha-trehalose + CoA
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(2)
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stearoyl-CoA + 2-O-sulfo-alpha,alpha-trehalose = 2-O-sulfo-2'-stearoyl-alpha,alpha-trehalose + CoA
show the reaction diagram
(1)
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PATHWAY SOURCE
PATHWAYS
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