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Information on EC 2.3.1.283 - 2'-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase

for references in articles please use BRENDA:EC2.3.1.283
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IUBMB Comments
This mycobacterial enzyme catalyses the acylation of 2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose at the 3' position by a (hydroxy)phthioceranoyl group during the biosynthesis of mycobacterial sulfolipids.
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Word Map
The expected taxonomic range for this enzyme is: Mycobacterium tuberculosis
Reaction Schemes
a (hydroxy)phthioceranyl-[(hydroxy)phthioceranic acid synthase]
+
2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose
=
a 3'-(hydroxy)phthioceranyl-2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose
+
holo-[(hydroxy)phthioceranic acid synthase]
Synonyms
papA1, Rv3824c, SL659 acyltransferase PapA1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a (hydroxy)phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose = a 3'-(hydroxy)phthioceranyl-2'-palmitoyl/stearoyl-2-O-sulfo-alpha,alpha-trehalose + holo-[(hydroxy)phthioceranic acid synthase]
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
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