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Information on EC 2.3.1.263 - 2-amino-4-oxopentanoate thiolase

for references in articles please use BRENDA:EC2.3.1.263

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IUBMB Comments

A pyridoxal 5′-phosphate enzyme. The enzyme, characterized from the bacterium Clostridium sticklandii, is part of a degradation pathway of ornithine. It is specific for acetyl-CoA and D-alanine.

The enzyme appears in viruses and cellular organisms

Synonyms
2-amino-4-ketopentanoate thiolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
acetyl-CoA + D-alanine = CoA + (2R)-2-amino-4-oxopentanoate
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
L-arginine degradation XIV (oxidative Stickland reaction)
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