Disease on EC 2.3.1.26 - sterol O-acyltransferase
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Abscess
Increasing prevalence of hypervirulent ST5 methicillin susceptible Staphylococcus aureus subtype poses a serious clinical threat.
Acantholysis
Peptides Targeting the Desmoglein 3 Adhesive Interface Prevent Autoantibody-induced Acantholysis in Pemphigus.
acetyl-coa c-acyltransferase deficiency
A Novel Mutation in ACAT1 Causing Beta-Ketothiolase Deficiency in a 4-Year-Old Sri Lankan Boy with Metabolic Ketoacidosis.
acetyl-coa c-acyltransferase deficiency
Beta-Ketothiolase Deficiency Presenting with Metabolic Stroke After a Normal Newborn Screen in Two Individuals.
acetyl-coa c-acyltransferase deficiency
C4OH is a potential newborn screening marker-a multicenter retrospective study of patients with beta-ketothiolase deficiency in China.
acetyl-coa c-acyltransferase deficiency
Clinical and Mutational Characterizations of Ten Indian Patients with Beta-Ketothiolase Deficiency.
acetyl-coa c-acyltransferase deficiency
NMR-based urinalysis for beta-ketothiolase deficiency.
acetyl-coa c-acyltransferase deficiency
Three Japanese Patients with Beta-Ketothiolase Deficiency Who Share a Mutation, c.431A>C (H144P) in ACAT1 : Subtle Abnormality in Urinary Organic Acid Analysis and Blood Acylcarnitine Analysis Using Tandem Mass Spectrometry.
acetyl-coa c-acyltransferase deficiency
[Analysis of clinical phenotype and ACAT1 gene mutation in a family affected with beta-ketothiolase deficiency].
Acne Vulgaris
All-trans-retinoic acid and 13-cis-retinoic acid: pharmacokinetics and biological activity in different cell culture models of human keratinocytes.
Acne Vulgaris
Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1?, and Tumor Necrosis Factor-? via a NF-?B-Dependent Mechanism in HaCaT Keratinocytes.
Acne Vulgaris
Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris.
Acne Vulgaris
[The influence of AMPs from HaCaT keratinocytes on some bacteria strains derived from skin changes]
Acute Coronary Syndrome
Cholesteryl esters associated with acyl-CoA:cholesterol acyltransferase predict coronary artery disease in patients with symptoms of acute coronary syndrome.
Adenocarcinoma
Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity.
Adenocarcinoma
Chemopreventive Activity of Polyphenolics from Black Jamapa Bean (Phaseolus vulgaris L.) on HeLa and HaCaT Cells.
Adenocarcinoma
Selected Compounds Structurally Related to Acyclic Sesquiterpenoids and Their Antibacterial and Cytotoxic Activity.
Adenocarcinoma
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Adenocarcinoma
Synthesis, structural characterization, docking simulation and in vitro antiproliferative activity of the new gold(III) complex with 2-pyridineethanol.
Adenocarcinoma
Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells.
Adenocarcinoma of Lung
A comparative study of using free radical generators in the testing of chosen oxidative stress parameters in the different types of cells.
Adenocarcinoma of Lung
AGR2-mediated lung adenocarcinoma metastasis novel mechanism network through repression with interferon coupling cytoskeleton to steroid metabolism-dependent humoral immune response.
Adenocarcinoma of Lung
Cytotoxic and ACAT-inhibitory sesquiterpene lactones from the root of Ixeris dentata forma albiflora.
Adenocarcinoma of Lung
Gefitinib-induced epidermal growth factor receptor (EGFR)-independent keratinocyte apoptosis is mediated by the JNK-activation pathway.
Adenocarcinoma of Lung
Mechanistic investigations of antitumor activity of a Rhodamine B?oleanolic acid derivative bioconjugate.
Adenocarcinoma of Lung
Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation.
Adenocarcinoma of Lung
Synthesis, structural characterization, docking simulation and in vitro antiproliferative activity of the new gold(III) complex with 2-pyridineethanol.
Adrenal Hyperplasia, Congenital
ATR-101, a selective ACAT1 inhibitor, decreases ACTH-stimulated cortisol concentrations in dogs with naturally occurring Cushing's syndrome.
Adrenal Insufficiency
Sterol O-Acyltransferase 1 (SOAT1, ACAT) Is a Novel Target of Steroidogenic Factor-1 (SF-1, NR5A1, Ad4BP) in the Human Adrenal.
Adrenocortical Carcinoma
A phase 1 study of nevanimibe HCl, a novel adrenal-specific sterol O-acyltransferase 1 (SOAT1) inhibitor, in adrenocortical carcinoma.
Adrenocortical Carcinoma
ATR-101, a selective ACAT1 inhibitor, decreases ACTH-stimulated cortisol concentrations in dogs with naturally occurring Cushing's syndrome.
Adrenocortical Carcinoma
ATR-101, a Selective and Potent Inhibitor of Acyl-CoA Acyltransferase 1, Induces Apoptosis in H295R Adrenocortical Cells and in the Adrenal Cortex of Dogs.
Adrenocortical Carcinoma
Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.
Adrenocortical Carcinoma
The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways.
Albuminuria
Regression of Atherosclerosis in Apolipoprotein E-Deficient Mice is Feasible Using High-Dose Angiotensin Receptor Blocker, Candesartan.
Albuminuria
Sterol-O-acyltransferase-1 has a role in kidney disease associated with diabetes and Alport Syndrome.
Alopecia
Minoxidil Acts as an Antiandrogen: A Study of 5?-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line.
Alopecia
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
Alopecia
Proprietary Herbal Extract Downregulates the Gene Expression of IL-1? in HaCaT Cells: Possible Implications Against Nonscarring Alopecia.
Alzheimer Disease
A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease.
Alzheimer Disease
ACAT1 as a therapeutic target and its genetic relationship with Alzheimer's disease.
Alzheimer Disease
ACAT1 is not associated with Alzheimer's disease in two independent family-based samples.
Alzheimer Disease
Acat1 knockdown gene therapy decreases amyloid-? in a mouse model of Alzheimer's disease.
Alzheimer Disease
Accumulation of neutral lipids in peripheral blood mononuclear cells as a distinctive trait of Alzheimer patients and asymptomatic subjects at risk of disease.
Alzheimer Disease
Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
Alzheimer Disease
Association between acyl-coenzyme A: cholesterol acyltransferase gene and risk for Alzheimer's disease in Chinese.
Alzheimer Disease
Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing.
Alzheimer Disease
Genetic association of acyl-coenzyme A: cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer's disease.
Alzheimer Disease
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases A?1-42 clearance.
Alzheimer Disease
Relationship Between Genetic Variants of ACAT1 and APOE with the Susceptibility to Dementia (SADEM Study).
Alzheimer Disease
Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces ?-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK.
Alzheimer Disease
Study on the association between SOAT1 polymorphisms, Alzheimer's disease risk and the level of CSF biomarkers.
Arteriosclerosis Obliterans
Lipid composition and enzyme activities of human arteriosclerotic femoral and iliac arteries.
Ataxia
Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.
Ataxia Telangiectasia
Knock-down of human MutY homolog (hMYH) decreases phosphorylation of checkpoint kinase 1 (Chk1) induced by hydroxyurea and UV treatment.
Ataxia Telangiectasia
Tetrandrine Enhances H2O2-Induced Apoptotic Cell Death Through Caspase-dependent Pathway in Human Keratinocytes.
Atherosclerosis
A glucagon-like peptide-1 analog liraglutide suppresses macrophage foam cell formation and atherosclerosis.
Atherosclerosis
A selective ACAT-1 inhibitor, K-604, suppresses fatty streak lesions in fat-fed hamsters without affecting plasma cholesterol levels.
Atherosclerosis
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
Atherosclerosis
ACAT inhibitor F-1394 prevents intimal hyperplasia induced by balloon injury in rabbits.
Atherosclerosis
ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver.
Atherosclerosis
Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis.
Atherosclerosis
Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis
Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice.
Atherosclerosis
Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies.
Atherosclerosis
Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.
Atherosclerosis
Anti-atherosclerotic molecules targeting oxidative stress and inflammation.
Atherosclerosis
Association Between LOX-1, LAL, and ACAT1 Gene Single Nucleotide Polymorphisms and Carotid Plaque in a Northern Chinese Population.
Atherosclerosis
Chemical modification of acyl-CoA:cholesterol O-acyltransferase. 2. Identification of a coenzyme A regulatory site by p-mercuribenzoate modification.
Atherosclerosis
Cholesterol esters (CE) derived from hepatic sterol O-acyltransferase 2 (SOAT2) are associated with more atherosclerosis than CE from intestinal SOAT2.
Atherosclerosis
Decreased microsomal membrane fluidity in the development of cholesterol-induced atherosclerosis in the rabbit.
Atherosclerosis
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.
Atherosclerosis
Dietary fat-induced alterations in atherosclerosis are abolished by ACAT2-deficiency in ApoB100 only, LDLr-/- mice.
Atherosclerosis
Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice.
Atherosclerosis
Effect of exogenous cholesterol and dithiothreitol on the activity of human liver microsomal acyl-coenzyme A:cholesterol acyltransferase (ACAT).
Atherosclerosis
Effect of F-1394, an acyl-CoA:cholesterol acyltransferase inhibitor, on atherosclerosis induced by high cholesterol diet in rabbits.
Atherosclerosis
Effect of the acyl-CoA:cholesterol acyltransferase inhibitor, E5324, on experimental atherosclerosis in rabbits.
Atherosclerosis
Effects of diazepam (Valium) on aortic atherogenesis and plasma lecithin: cholesterol acyltransferase activity in cockerels fed an atherogenic diet.
Atherosclerosis
Effects of leptin on expression of acyl-coenzymea: cholesterol acyltransferases-1 in cultured human monocyte-macrophages.
Atherosclerosis
Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.
Atherosclerosis
Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone.
Atherosclerosis
Estrogen decreases atherosclerosis in part by reducing hepatic acyl-CoA:cholesterol acyltransferase 2 (ACAT2) in monkeys.
Atherosclerosis
Expression of ACAT-1 protein in human atherosclerotic lesions and cultured human monocytes-macrophages.
Atherosclerosis
Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice.
Atherosclerosis
HL-004, the ACAT inhibitor, prevents the progression of atherosclerosis in cholesterol-fed rabbits.
Atherosclerosis
Homocysteine-mediated cholesterol efflux via ABCA1 and ACAT1 DNA methylation in THP-1 monocyte-derived foam cells.
Atherosclerosis
Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ.
Atherosclerosis
Human ACAT1 gene expression and its involvement in the development of atherosclerosis.
Atherosclerosis
Human Acyl-CoA:cholesterol Acyltransferase (ACAT) and its Potential as a Target for Pharmaceutical Intervention against Atherosclerosis.
Atherosclerosis
Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.
Atherosclerosis
Human acyl-CoA:cholesterol acyltransferase-1 is a homotetrameric enzyme in intact cells and in vitro.
Atherosclerosis
Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages.
Atherosclerosis
Identification of potential ACAT-2 selective inhibitors using pharmacophore, SVM and SVR from Chinese herbs.
Atherosclerosis
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A.
Atherosclerosis
Imidazolylbenzopyrane derivatives: a new class of acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors.
Atherosclerosis
Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis.
Atherosclerosis
Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages.
Atherosclerosis
Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow.
Atherosclerosis
Inhibitory effect of acyl-CoA:cholesterol acyltransferase inhibitor-low density lipoprotein complex on experimental atherosclerosis.
Atherosclerosis
Insulin induces human acyl-coenzyme A: cholesterol acyltransferase1 gene expression via MAP kinases and CCAAT/enhancer-binding protein ?.
Atherosclerosis
Intravascular ultrasound assessment of novel antiatherosclerotic therapies: rationale and design of the Acyl-CoA:Cholesterol Acyltransferase Intravascular Atherosclerosis Treatment Evaluation (ACTIVATE) Study.
Atherosclerosis
LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis.
Atherosclerosis
Lipids-induced apoptosis is aggravated by acyl-coenzyme A: cholesterol acyltransferase inhibitor.
Atherosclerosis
Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice.
Atherosclerosis
Loss of ACAT1 Attenuates Atherosclerosis Aggravated by Loss of NCEH1 in Bone Marrow-Derived Cells.
Atherosclerosis
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.
Atherosclerosis
Molecular aspects of intracellular sterol esterification: the acyl coenzyme A: cholesterol acyltransferase reaction.
Atherosclerosis
Molecular structures of human ACAT2 disclose mechanism for selective inhibition.
Atherosclerosis
Mutant acyl-coenzyme A:cholesterol acyltransferase 1 devoid of cysteine residues remains catalytically active.
Atherosclerosis
Myeloid Acat1/Soat1 KO attenuates pro-inflammatory responses in macrophages and protects against atherosclerosis in a model of advanced lesions.
Atherosclerosis
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
Atherosclerosis
New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models.
Atherosclerosis
Nonoxidative ethanol metabolism: formation of fatty acid ethyl esters by cholesterol esterase.
Atherosclerosis
NTE-122, an acyl-coa:cholesterol acyltransferase inhibitor, prevents the progression of atherogenesis in cholesterol-fed rabbits.
Atherosclerosis
Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.
Atherosclerosis
Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms.
Atherosclerosis
Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Atherosclerosis
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis.
Atherosclerosis
Pyripyropene A, an Acyl-Coenzyme A:Cholesterol Acyltransferase 2-Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia.
Atherosclerosis
Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1.
Atherosclerosis
Regression of Atherosclerosis in Apolipoprotein E-Deficient Mice is Feasible Using High-Dose Angiotensin Receptor Blocker, Candesartan.
Atherosclerosis
Rimonabant is a dual inhibitor of acyl CoA:cholesterol acyltransferases 1 and 2.
Atherosclerosis
Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein.
Atherosclerosis
Role of the N-terminal hydrophilic domain of acyl-coenzyme A:cholesterol acyltransferase 1 on the enzyme's quaternary structure and catalytic efficiency.
Atherosclerosis
Sex-specific association of ACAT-1 rs1044925 SNP and serum lipid levels in the hypercholesterolemic subjects.
Atherosclerosis
Short-Term Acyl-CoA:Cholesterol Acyltransferase Inhibition, Combined with Apoprotein A1 Overexpression, Promotes Atherosclerosis Inflammation Resolution in Mice.
Atherosclerosis
SOAT1 deficiency attenuates atherosclerosis by regulating inflammation and cholesterol transportation via HO-1 pathway.
Atherosclerosis
Synthesis and Evaluation of 11C- and 18F-Labeled SOAT1 Inhibitors as Macrophage Foam Cell Imaging Agents.
Atherosclerosis
Targeted Depletion of Hepatic ACAT2-driven Cholesterol Esterification Reveals a Non-biliary Route for Fecal Neutral Sterol Loss.
Atherosclerosis
Targeted Knockdown of Hepatic SOAT2 With Antisense Oligonucleotides Stabilizes Atherosclerotic Plaque in ApoB100-only LDLr-/- Mice.
Atherosclerosis
The hypolipidemic effect of a new ACAT inhibitor, VULM 1457, in diabetic-hypercholesterolaemic rats.
Atherosclerosis
[Construction and identification of recombinant firefly luciferase report vector containing human acyl coenzyme a: cholesterol acyltransferase 1 gene P7 promoter]
Atherosclerosis
[Ghrelin down-regulates ACAT-1 in THP-1 derived foam cells via growth hormone secretagogue receptor-dependent pathway]
Atherosclerosis
[Involvement of phospholipase A2 in the supply of fatty acids required for cholesterol esterification associated with uptake of oxidized low-density lipoprotein in macrophages]
Autoimmune Diseases
Role of tumor necrosis factor-? in the regulation of keratinocyte cell cycle and DNA repair after ultraviolet-B radiation.
Bacterial Infections
Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin.
Bacterial Infections
Leucocyte recruitment and molecular fortification of keratinocytes triggered by streptococcal M1 protein.
Bacterial Infections
Streptococcus pyogenes infection of tonsil explants is associated with a human ?-defensin 1 response from control but not recurrent acute tonsillitis patients.
Blister
Bikunin, a serine protease inhibitor, is present on the cell boundary of epidermis.
Blister
Decreased phospholipase D (PLD) activity in ceramide-induced apoptosis of human keratinocyte cell line HaCaT.
Blister
Plasmin Plays a Role in the In Vitro Generation of the Linear IgA Dermatosis Antigen LADB97.
Bowen's Disease
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Bowen's Disease
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Breast Neoplasms
?-hydroxybutyrate does not alter the effects of glucose deprivation on breast cancer cells.
Breast Neoplasms
A Comparative Study of Melissa officinalis Leaves and Stems Ethanolic Extracts in terms of Antioxidant, Cytotoxic, and Antiproliferative Potential.
Breast Neoplasms
A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17.
Breast Neoplasms
Anticarcinogenic activity of blue fluorescent hexagonal boron nitride quantum dots: as an effective enhancer for DNA cleavage activity of anticancer drug doxorubicin.
Breast Neoplasms
Antineoplastic potential and chemical evaluation of essential oils from leaves and flowers of Tagetes ostenii Hicken.
Breast Neoplasms
Bacillus thuringiensis toxins are cytotoxic to cervical cancer (HeLa) but not to breast cancer (MCF7) cells.
Breast Neoplasms
Cholesteryl Ester Promotes Mammary Tumor Growth in MMTV-PyMT Mice and Activates Akt-mTOR Pathway in Tumor Cells.
Breast Neoplasms
Conserved CPEs in the p53 3' untranslated region influence mRNA stability and protein synthesis.
Breast Neoplasms
Disrupting cholesterol esterification by bitter melon suppresses triple-negative breast cancer cell growth.
Breast Neoplasms
Efficient hydrolytic cleavage of DNA and antiproliferative effect on human cancer cells by two dinuclear Cu(II) complexes containing a carbohydrazone ligand and 1,10-phenanthroline as a coligand.
Breast Neoplasms
Gold Nano-Popcorn Attached SWCNT Hybrid Nanomaterial for Targeted Diagnosis and Photothermal Therapy of Human Breast Cancer Cells.
Breast Neoplasms
Green synthesis of multifunctional silver and gold nanoparticles from the oriental herbal adaptogen: Siberian ginseng.
Breast Neoplasms
High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation.
Breast Neoplasms
Imaging Nuclei of MDA-MB-231 Breast Cancer Cells by Chiral Ruthenium(II) Complex Coordinated by 2-(4-Phenyacetylenephenyl)-1H-imidazo[4,5f][1,10]phenanthroline.
Breast Neoplasms
Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines.
Breast Neoplasms
Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2.
Breast Neoplasms
Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members.
Breast Neoplasms
MicroRNA 10b promotes abnormal expression of the protooncogene c-Jun in metastatic breast cancer cells.
Breast Neoplasms
Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification.
Breast Neoplasms
Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs).
Breast Neoplasms
Monofunctional BODIPY-Appended Imidazoplatin for Cellular Imaging and Mitochondria-Targeted Photocytotoxicity.
Breast Neoplasms
Multifunctional oval-shaped gold-nanoparticle-based selective detection of breast cancer cells using simple colorimetric and highly sensitive two-photon scattering assay.
Breast Neoplasms
Novel 2-benzylthio-5-(1,3,4-oxadiazol-2-yl)benzenesulfonamides with anticancer activity: Synthesis, QSAR study, and metabolic stability.
Breast Neoplasms
Quantitative assessment of the relative antineoplastic potential of the n-butanolic leaf extract of Annona muricata Linn. in normal and immortalized human cell lines.
Breast Neoplasms
Role of breast tumour kinase in the in vitro differentiation of HaCaT cells.
Breast Neoplasms
Synthesis and biological evaluation of 4-biphenylamino-5-halo-2(5H)-furanones as potential anticancer agents.
Breast Neoplasms
Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent.
Caliciviridae Infections
Synthesis and anti-norovirus activity of pyranobenzopyrone compounds.
Carcinogenesis
A novel chemopreventive mechanism for a traditional medicine: East Indian sandalwood oil induces autophagy and cell death in proliferating keratinocytes.
Carcinogenesis
Aberrant cytokeratin expression during arsenic-induced acquired malignant phenotype in human HaCaT keratinocytes consistent with epidermal carcinogenesis.
Carcinogenesis
Angiotensin II enhances EGF receptor expression levels via ROS formation in HaCaT cells.
Carcinogenesis
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure.
Carcinogenesis
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Carcinogenesis
Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.
Carcinogenesis
Delayed and sustained activation of extracellular signal-regulated kinase in human keratinocytes by UVA: implications in carcinogenesis.
Carcinogenesis
Differential stromal regulation of MMP-1 expression in benign and malignant keratinocytes.
Carcinogenesis
Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis.
Carcinogenesis
Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity.
Carcinogenesis
Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs).
Carcinogenesis
Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.
Carcinogenesis
Nemosis of fibroblasts is inhibited by benign HaCaT keratinocytes but promoted by malignant HaCaT cells.
Carcinogenesis
Neoplastic alterations induced in Mammalian skin following mancozeb exposure using in vivo and in vitro models.
Carcinogenesis
Novel Processed Form of Syndecan-1 Shed from SCC-9 Cells Plays a Role in Cell Migration.
Carcinogenesis
Opposite roles of protein kinase C isoforms in proliferation, differentiation, apoptosis, and tumorigenicity of human HaCaT keratinocytes.
Carcinogenesis
Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links.
Carcinogenesis
Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells.
Carcinogenesis
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Carcinogenesis
Protective Effect of Inositol Hexaphosphate Against UVB Damage in HaCaT Cells and Skin Carcinogenesis in SKH1 Hairless Mice.
Carcinogenesis
Rac1 is required for oncolytic NDV replication in human cancer cells and establishes a link between tumorigenesis and sensitivity to oncolytic virus.
Carcinogenesis
Role of tumor necrosis factor-? in the regulation of keratinocyte cell cycle and DNA repair after ultraviolet-B radiation.
Carcinogenesis
Selective cytotoxicity of Aniba rosaeodora essential oil towards epidermoid cancer cells through induction of apoptosis.
Carcinogenesis
Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes.
Carcinogenesis
TGF-beta isoforms are differentially expressed in increasing malignant grades of HaCaT keratinocytes, suggesting separate roles in skin carcinogenesis.
Carcinogenesis
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-?B.
Carcinogenesis
The mRNA Expression Signature and Prognostic Analysis of Multiple Fatty Acid Metabolic Enzymes in Clear Cell Renal Cell Carcinoma.
Carcinoma
A comparative study of using free radical generators in the testing of chosen oxidative stress parameters in the different types of cells.
Carcinoma
A dairy bacterium displays in vitro probiotic properties for the pharyngeal mucosa by antagonizing group A streptococci and modulating the immune response.
Carcinoma
A New Survival Model Based on Cholesterol Biosynthesis-Related Genes for Prognostic Prediction in Clear Cell Renal Cell Carcinoma.
Carcinoma
A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities.
Carcinoma
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
Carcinoma
ACAT1 and Metabolism-Related Pathways Are Essential for the Progression of Clear Cell Renal Cell Carcinoma (ccRCC), as Determined by Co-expression Network Analysis.
Carcinoma
Actin isoforms and reorganization of adhesion junctions in epithelial-to-mesenchymal transition of cervical carcinoma cells.
Carcinoma
All-trans-retinoic acid-mediated growth inhibition involves inhibition of human kinesin-related protein HsEg5.
Carcinoma
Altered biology of adeno-associated virus type 2 and human papillomavirus during dual infection of natural host tissue.
Carcinoma
Ambivalent Effects of Tumor Necrosis Factor Alpha on Apoptosis of Malignant and Normal Human Keratinocytes.
Carcinoma
Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity.
Carcinoma
Antiproliferative Effects on Tumour Cells and Promotion of Keratinocyte Wound Healing by Different Lichen Compounds.
Carcinoma
Apoptotic mechanism activated by blue light and cisplatinum in cutaneous squamous cell carcinoma cells.
Carcinoma
Camptothecin Fails to Induce Apoptosis in Tumor Necrosis Factor-Alpha-Treated HaCaT Cells.
Carcinoma
CBP-mediated Wnt3a/?-catenin signaling promotes cervical oncogenesis initiated by Piwil2.
Carcinoma
CD151 dynamics in carcinoma-stroma interaction: integrin expression, adhesion strength and proteolytic activity.
Carcinoma
Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas.
Carcinoma
Chemical Characterization and in Vitro Cytotoxicity on Squamous Cell Carcinoma Cells of Carica Papaya Leaf Extracts.
Carcinoma
Chromium(III) oxide nanoparticles induced remarkable oxidative stress and apoptosis on culture cells.
Carcinoma
Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2.
Carcinoma
Constitutive expression of G-CSF and GM-CSF in human skin carcinoma cells with functional consequence for tumor progression.
Carcinoma
Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of skin carcinoma cells.
Carcinoma
Cytotoxic and ACAT-inhibitory sesquiterpene lactones from the root of Ixeris dentata forma albiflora.
Carcinoma
Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexes.
Carcinoma
Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.
Carcinoma
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma
Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis.
Carcinoma
Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.
Carcinoma
Different pathways are involved in arsenic-trioxide-induced cell proliferation and growth inhibition in human keratinocytes.
Carcinoma
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer.
Carcinoma
Early phase TGF? receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses.
Carcinoma
Effect of chromodomain helicase/ATPase DNA binding protein 1-like gene on the invasion and metastasis of tongue squamous cell carcinoma CAL27 cells.
Carcinoma
Effect of inhibiting ACAT-1 expression on the growth and metastasis of Lewis lung carcinoma.
Carcinoma
Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells.
Carcinoma
Egg-Yolk Sphingomyelin and Phosphatidylcholine Attenuate Cholesterol Absorption in Caco-2 Cells.
Carcinoma
Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.
Carcinoma
Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair.
Carcinoma
Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.
Carcinoma
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Carcinoma
Expression of two isozymes of acyl-coenzyme A: cholesterol acyltransferase-1 and -2 in clear cell type renal cell carcinoma.
Carcinoma
Gold nanoparticles conjugated with programmed death-ligand 1 antibodies induce apoptosis of SCC-25 oral squamous cell carcinoma cells via programmed death-ligand 1/signal transducer and transcription 3 pathway.
Carcinoma
Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.
Carcinoma
In vitro evaluation of cellular influences induced by stable fullerene C70 medium dispersion: Induction of cellular oxidative stress.
Carcinoma
In vitro evaluation of cellular responses induced by stable fullerene C60 medium dispersion.
Carcinoma
In vitro sensitivity of human gastric cancer cells (HGC-27) to Helicobacter pylori cytotoxin.
Carcinoma
Influence of activation and differentiation of cells on the effectiveness of photodynamic therapy.
Carcinoma
Inhibition of basal cell carcinoma cells by cold atmospheric plasma?activated solution and differential gene expression analysis.
Carcinoma
Inhibition of Cholesterol Esterification Enzyme Enhances the Potency of Human Chimeric Antigen Receptor T Cells against Pancreatic Carcinoma.
Carcinoma
Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells.
Carcinoma
Iodinated chlorin p6 copper complex induces anti-proliferative effect in oral cancer cells through elevation of intracellular reactive oxygen species.
Carcinoma
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Carcinoma
Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma.
Carcinoma
Methylation-associated silencing of S100A4 expression in human epidermal cancers.
Carcinoma
Molecular basis of basal cell carcinoma: analysis of differential gene expression by differential display PCR and expression array.
Carcinoma
Myricetin and naringenin inhibit human squamous cell carcinoma proliferation and migration in vitro.
Carcinoma
Novel N-(aryl/heteroaryl)-2-chlorobenzenesulfonamide derivatives: Synthesis and anticancer activity evaluation.
Carcinoma
Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-?.
Carcinoma
Overexpression of HOXB7 homeobox gene in oral cancer induces cellular proliferation and is associated with poor prognosis.
Carcinoma
Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.
Carcinoma
Phenolic profiling of an extract from Eugenia jambos L. (Alston)--the structure of three flavonoid glycosides--antioxidant and cytotoxic activities.
Carcinoma
Photodynamic therapy of tumour cells mediated by the natural anthraquinone parietin and blue light.
Carcinoma
Photosensitization of human skin cell lines by ATMPn (9-acetoxy-2,7,12,17-tetrakis-(beta-methoxyethyl)-porphycene) in vitro: mechanism of action.
Carcinoma
Photosensitization of skin-derived cell lines by Dimegin [2,4-di-(alpha-methoxyethyl)-deuteroporphyrin IX] in vitro.
Carcinoma
Possible Involvement of F1F0-ATP synthase and Intracellular ATP in Keratinocyte Differentiation in normal skin and skin lesions.
Carcinoma
Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Carcinoma
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Carcinoma
Protein Adsorption of Ultrafine Metal Oxide and Its Influence on Cytotoxicity toward Cultured Cells.
Carcinoma
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
Carcinoma
Regulation of cholesterol metabolism and low-density lipoprotein binding in human intestinal Caco-2 cells.
Carcinoma
Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.
Carcinoma
Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity.
Carcinoma
Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).
Carcinoma
Surface plasmon resonance-biosensor detects the diversity of responses against epidermal growth factor in various carcinoma cell lines.
Carcinoma
Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent.
Carcinoma
Synthesis and In?Vitro Evaluation of a Photosensitizer-BODIPY Derivative for Potential Photodynamic Therapy Applications.
Carcinoma
Synthesis, structural characterization, docking simulation and in vitro antiproliferative activity of the new gold(III) complex with 2-pyridineethanol.
Carcinoma
The biochemical alterations following administration of Kalpaamruthaa and Semecarpus anacardium in mammary carcinoma.
Carcinoma
The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells.
Carcinoma
The epidermal platelet-activating factor receptor augments chemotherapy-induced apoptosis in human carcinoma cell lines.
Carcinoma
The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C.
Carcinoma
The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation.
Carcinoma
The novel synthetic ether lipid inositol-C2-PAF inhibits phosphorylation of the tyrosine kinases Src and FAK independent of integrin activation in transformed skin cells.
Carcinoma
The relative abundance of oxygen alkyl-related groups in aliphatic domains is involved in the main pharmacological-pleiotropic effects of humic acids.
Carcinoma
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.
Carcinoma
Transcriptional activation of the human papillomavirus-16 P97 promoter by an 88-nucleotide enhancer containing distinct cell-dependent and AP-1-responsive modules.
Carcinoma
Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells.
Carcinoma
Ultrafine NiO Particles Induce Cytotoxicity in Vitro by Cellular Uptake and Subsequent Ni(II) Release.
Carcinoma
[Differences of Nonsense-Mediated mRNA Degradation Activity in Mammalian Cell Lines Revealed by a Fluorescence Reporter].
Carcinoma
[Effects of RAB1A on the proliferation, invasion, and metastasis of tongue squamous cell carcinoma cells].
Carcinoma
[Expression of vascular endothelial growth factor and its receptors in laryngeal carcinoma cell and its significance]
Carcinoma
[Over-expression of Hsa-miR-23b-3p suppresses proliferation, migration, invasion and epithelial-mesenchymal transition of human cervical cancer CasKi cells].
Carcinoma, Basal Cell
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma, Basal Cell
Inhibition of basal cell carcinoma cells by cold atmospheric plasma?activated solution and differential gene expression analysis.
Carcinoma, Hepatocellular
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
Carcinoma, Hepatocellular
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer.
Carcinoma, Hepatocellular
Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells.
Carcinoma, Hepatocellular
Correction: Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effects of NTE-122, a novel acyl-CoA:cholesterol acyltransferase inhibitor, on cholesterol esterification and secretions of apolipoprotein B-containing lipoprotein and bile acids in HepG2.
Carcinoma, Hepatocellular
Generation of new hepatocyte-like in vitro models better resembling human lipid metabolism.
Carcinoma, Hepatocellular
Human acyl-CoA:cholesterol acyltransferase 2 gene expression in intestinal Caco-2 cells and in hepatocellular carcinoma.
Carcinoma, Hepatocellular
Impacts of the SOAT1 genetic variants and protein expression on HBV-related hepatocellular carcinoma.
Carcinoma, Hepatocellular
Inhibition of acyl-CoA: cholesterol acyltransferase decreases apolipoprotein B-100-containing lipoprotein secretion from HepG2 cells.
Carcinoma, Hepatocellular
Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes.
Carcinoma, Hepatocellular
Physicochemical, Bacteriostatic, and Biological Properties of Starch/Chitosan Polymer Composites Modified by Graphene Oxide, Designed as New Bionanomaterials.
Carcinoma, Hepatocellular
Proteomic heterogeneity reveals SOAT1 as a potential biomarker for hepatocellular carcinoma.
Carcinoma, Hepatocellular
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma.
Carcinoma, Hepatocellular
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Carcinoma, Hepatocellular
Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent.
Carcinoma, Hepatocellular
Use of cyclodextrins for manipulating cellular cholesterol content.
Carcinoma, Lewis Lung
Effect of inhibiting ACAT-1 expression on the growth and metastasis of Lewis lung carcinoma.
Carcinoma, Lewis Lung
The relative abundance of oxygen alkyl-related groups in aliphatic domains is involved in the main pharmacological-pleiotropic effects of humic acids.
Carcinoma, Lewis Lung
[Differences of Nonsense-Mediated mRNA Degradation Activity in Mammalian Cell Lines Revealed by a Fluorescence Reporter].
Carcinoma, Merkel Cell
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Carcinoma, Non-Small-Cell Lung
Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity.
Carcinoma, Renal Cell
ACAT1 and Metabolism-Related Pathways Are Essential for the Progression of Clear Cell Renal Cell Carcinoma (ccRCC), as Determined by Co-expression Network Analysis.
Carcinoma, Renal Cell
Circ_RPL23A acts as a miR-1233 sponge to suppress the progression of clear cell renal cell carcinoma by promoting ACAT2.
Carcinoma, Renal Cell
Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Carcinoma, Squamous Cell
Altered biology of adeno-associated virus type 2 and human papillomavirus during dual infection of natural host tissue.
Carcinoma, Squamous Cell
Ambivalent Effects of Tumor Necrosis Factor Alpha on Apoptosis of Malignant and Normal Human Keratinocytes.
Carcinoma, Squamous Cell
Annexin A5 is involved in migration and invasion of oral carcinoma.
Carcinoma, Squamous Cell
Anti-proliferative and pro-apoptotic effects of Uncaria tomentosa aqueous extract in squamous carcinoma cells.
Carcinoma, Squamous Cell
Apoptotic mechanism activated by blue light and cisplatinum in cutaneous squamous cell carcinoma cells.
Carcinoma, Squamous Cell
Artesunate induces G0/G1 cell cycle arrest and iron-mediated mitochondrial apoptosis in A431 human epidermoid carcinoma cells.
Carcinoma, Squamous Cell
Cell cycle progression data on human skin cancer cells with anticancer synthetic peptide LTX-315 treatment.
Carcinoma, Squamous Cell
Cell-matrix interactions of normal and transformed human keratinocytes in vitro are modulated by the synthetic phospholipid analogue hexadecylphosphocholine.
Carcinoma, Squamous Cell
Characterization of corticotropin-releasing hormone (CRH) in human skin.
Carcinoma, Squamous Cell
Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of skin carcinoma cells.
Carcinoma, Squamous Cell
Correlation between FUT4 expression and its promoter methylation in HaCaT cells.
Carcinoma, Squamous Cell
Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo.
Carcinoma, Squamous Cell
Cyclosporin A induces the unfolded protein response in keratinocytes.
Carcinoma, Squamous Cell
Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexes.
Carcinoma, Squamous Cell
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma, Squamous Cell
Development and Characterization of a Novel in vitro Progression Model for UVB-Induced Skin Carcinogenesis.
Carcinoma, Squamous Cell
Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair.
Carcinoma, Squamous Cell
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer.
Carcinoma, Squamous Cell
Effect of chromodomain helicase/ATPase DNA binding protein 1-like gene on the invasion and metastasis of tongue squamous cell carcinoma CAL27 cells.
Carcinoma, Squamous Cell
Effects of demethoxycurcumin on the viability and apoptosis of skin cancer cells.
Carcinoma, Squamous Cell
EGFR-Dependent Downregulation of Bim in Epithelial Cells Requires MAPK and PKC-delta Activities.
Carcinoma, Squamous Cell
Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.
Carcinoma, Squamous Cell
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Carcinoma, Squamous Cell
GPI-specific phospholipase D mRNA expression in tumor cells of different malignancy.
Carcinoma, Squamous Cell
Indocyanine green (ICG) and laser irradiation induce photooxidation.
Carcinoma, Squamous Cell
Influence of activation and differentiation of cells on the effectiveness of photodynamic therapy.
Carcinoma, Squamous Cell
Jasmonic Acid Induces Endoplasmic Reticulum Stress with Different Outcome in Cultured Normal and Tumor Epidermal Cells.
Carcinoma, Squamous Cell
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Carcinoma, Squamous Cell
Methylation-associated silencing of S100A4 expression in human epidermal cancers.
Carcinoma, Squamous Cell
Mitogen- and stress-activated protein kinase 1 is critical for interleukin-1-induced, CREB-mediated, c-fos gene expression in keratinocytes.
Carcinoma, Squamous Cell
Molecular basis of basal cell carcinoma: analysis of differential gene expression by differential display PCR and expression array.
Carcinoma, Squamous Cell
Patterns of desmocollin synthesis in human epithelia: immunolocalization of desmocollins 1 and 3 in special epithelia and in cultured cells.
Carcinoma, Squamous Cell
Photosensitization of human skin cell lines by ATMPn (9-acetoxy-2,7,12,17-tetrakis-(beta-methoxyethyl)-porphycene) in vitro: mechanism of action.
Carcinoma, Squamous Cell
Photosensitization of skin-derived cell lines by Dimegin [2,4-di-(alpha-methoxyethyl)-deuteroporphyrin IX] in vitro.
Carcinoma, Squamous Cell
Possible Involvement of F1F0-ATP synthase and Intracellular ATP in Keratinocyte Differentiation in normal skin and skin lesions.
Carcinoma, Squamous Cell
Regulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.
Carcinoma, Squamous Cell
Resveratrol enhances the effects of ALA-PDT on skin squamous cells A431 through p38/ MAPK signaling pathway.
Carcinoma, Squamous Cell
Retinoids downregulate vascular endothelial growth factor/vascular permeability factor production by normal human keratinocytes.
Carcinoma, Squamous Cell
Roles of heterogeneous nuclear ribonucleoproteins A and B in cell proliferation.
Carcinoma, Squamous Cell
Sanguinarine causes cell cycle blockade and apoptosis of human prostate carcinoma cells via modulation of cyclin kinase inhibitor-cyclin-cyclin-dependent kinase machinery.
Carcinoma, Squamous Cell
Selective cytotoxicity of Aniba rosaeodora essential oil towards epidermoid cancer cells through induction of apoptosis.
Carcinoma, Squamous Cell
Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).
Carcinoma, Squamous Cell
Synthesis and Characterization of 3-(1-((3,4-Dihydroxyphenethyl)amino)ethylidene)-chroman-2,4-dione as a Potential Antitumor Agent.
Carcinoma, Squamous Cell
Synthesis and Cytostatic Effect of 3'-deoxy-3'-C-Sulfanylmethyl Nucleoside Derivatives with d-xylo Configuration.
Carcinoma, Squamous Cell
The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells.
Carcinoma, Squamous Cell
The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells.
Carcinoma, Squamous Cell
The expression of desmoglein isoforms in cultured human keratinocytes is regulated by calcium, serum, and protein kinase C.
Carcinoma, Squamous Cell
The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation.
Carcinoma, Squamous Cell
The novel synthetic ether lipid inositol-C2-PAF inhibits phosphorylation of the tyrosine kinases Src and FAK independent of integrin activation in transformed skin cells.
Carcinoma, Squamous Cell
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.
Carcinoma, Squamous Cell
Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells.
Carcinoma, Squamous Cell
Verbascum nigrum: Cytotoxicity Evaluation in A431 Epidermoid Carcinoma Cells and Untargeted LC-HR-MS/MS Metabolite Profiling.
Carcinoma, Squamous Cell
[Effect of plant hormones on the components of secretory pathway in human normal and tumor cells].
Carcinoma, Squamous Cell
[Effects of RAB1A on the proliferation, invasion, and metastasis of tongue squamous cell carcinoma cells].
Cardiovascular Diseases
Isoform-specific inhibitors of ACATs: recent advances and promising developments.
Cardiovascular Diseases
Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice.
Cardiovascular Diseases
Molecular structures of human ACAT2 disclose mechanism for selective inhibition.
Cell Transformation, Neoplastic
Rac1 is required for oncolytic NDV replication in human cancer cells and establishes a link between tumorigenesis and sensitivity to oncolytic virus.
Cell Transformation, Neoplastic
UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes.
Chagas Disease
ACAT-1 gene rs1044925 SNP and its relation with different clinical forms of chronic Chagas disease.
Cholangiocarcinoma
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
Cholelithiasis
ACAT2 and human hepatic cholesterol metabolism: Identification of important gender-related differences in normolipidemic, non-obese Chinese patients.
Cholelithiasis
Effect of exogenous cholesterol and dithiothreitol on the activity of human liver microsomal acyl-coenzyme A:cholesterol acyltransferase (ACAT).
Cholelithiasis
The ACAT2 gene encodes a gatekeeper of intestinal cholesterol absorption that regulates cholesterolemia and gallstone disease.
Cholera
Cholesterol-rich plasma membrane domains (lipid rafts) in keratinocytes: importance in the baseline and UVA-induced generation of reactive oxygen species.
Cholesteatoma
Modeling the cholesteatoma microenvironment: coculture of HaCaT keratinocytes with WS1 fibroblasts induces MMP-2 activation, invasive phenotype, and proteolysis of the extracellular matrix.
Cholesteatoma
TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma.
Cholesteatoma
[Expression and activation of nuclear factor-kappaB in middle ear cholesteatoma]
Cholesteatoma, Middle Ear
TFIIB-related factor 2 regulates glucose-regulated protein 78 expression in acquired middle ear cholesteatoma.
Cockayne Syndrome
Downregulation of Cockayne syndrome B protein reduces human 8-oxoguanine DNA glycosylase-1 expression and repair of UV radiation-induced 8-oxo-7,8-dihydro-2'-deoxyguanine.
Colonic Neoplasms
Anti-cancer effects of Porphyra haitanensis polysaccharides on human colon cancer cells via cell cycle arrest and apoptosis without causing adverse effects in vitro.
Colonic Neoplasms
Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis.
Colonic Neoplasms
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Colonic Neoplasms
Crosstalk between Hippo and TGF?: Subcellular Localization of YAP/TAZ/Smad Complexes.
Colonic Neoplasms
Crucial role of cytokines in sex steroid formation in normal and tumoral tissues.
Colonic Neoplasms
Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway.
Colonic Neoplasms
Fargesin Inhibits EGF-Induced Cell Transformation and Colon Cancer Cell Growth by Suppression of CDK2/Cyclin E Signaling Pathway.
Colonic Neoplasms
In situ preparation of water-soluble ginsenoside Rh2-entrapped bovine serum albumin nanoparticles: in vitro cytocompatibility studies.
Colonic Neoplasms
Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines.
Colonic Neoplasms
Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes.
Colonic Neoplasms
Novel 2-benzylthio-5-(1,3,4-oxadiazol-2-yl)benzenesulfonamides with anticancer activity: Synthesis, QSAR study, and metabolic stability.
Colonic Neoplasms
PAF-receptor in inflammatory versus non inflammatory human epidermis, cell cultures and embryonal cells.
Colonic Neoplasms
Regulation of cholesterol metabolism and low-density lipoprotein binding in human intestinal Caco-2 cells.
Colonic Neoplasms
Resveratrol enhances apoptosis induced by the heterocyclic aromatic amines in p53-wt LoVo cells, but not in p53-deficient HaCaT cells.
Colonic Neoplasms
SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue.
Colonic Neoplasms
The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses.
Colorectal Neoplasms
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer.
Colorectal Neoplasms
Enhancement of p53-mutant human colorectal cancer cells radiosensitivity by flavonoid fisetin.
Colorectal Neoplasms
Erratum: ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer [Corrigendum].
Colorectal Neoplasms
Insulin promotes progression of colon cancer by upregulation of ACAT1.
Colorectal Neoplasms
Serum Starvation Sensitizes Anticancer Effect of Anemarrhena asphodeloides via p38/JNK-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells.
Colorectal Neoplasms
TLR4 siRNA inhibits proliferation and invasion in colorectal cancer cells by downregulating ACAT1 expression.
Condylomata Acuminata
The cytotoxic mechanism of epigallocatechin gallate on proliferative HaCaT keratinocytes.
Coronary Artery Disease
Acyl-CoA: cholesterol acyltransferases-2 gene polymorphism is associated with increased susceptibility to coronary artery disease in Uygur population in Xinjiang, China.
Coronary Artery Disease
Cholesteryl esters associated with acyl-CoA:cholesterol acyltransferase predict coronary artery disease in patients with symptoms of acute coronary syndrome.
Coronary Artery Disease
Functional characterization of two single nucleotide polymorphisms of acyl-coenzyme A:cholesterol acyltransferase 2.
Coronary Artery Disease
Intravascular ultrasound assessment of novel antiatherosclerotic therapies: rationale and design of the Acyl-CoA:Cholesterol Acyltransferase Intravascular Atherosclerosis Treatment Evaluation (ACTIVATE) Study.
Coronary Artery Disease
Reduced regulatory capacity of low density lipoproteins from patients with coronary artery disease.
Coronary Disease
ACAT2 and human hepatic cholesterol metabolism: Identification of important gender-related differences in normolipidemic, non-obese Chinese patients.
Coronary Disease
ACAT2 is a target for treatment of coronary heart disease associated with hypercholesterolemia.
Coronary Disease
Monounsaturated fatty acyl-coenzyme A is predictive of atherosclerosis in human apoB-100 transgenic, LDLr-/- mice.
Coronary Disease
Role of multidrug resistance P-glycoproteins in cholesterol esterification.
Crohn Disease
Interruption of the enterohepatic circulation of bile acids stimulates the esterification rate of cholesterol in human liver.
Cushing Syndrome
ATR-101, a selective ACAT1 inhibitor, decreases ACTH-stimulated cortisol concentrations in dogs with naturally occurring Cushing's syndrome.
Dehydration
Far infrared ray irradiation attenuates apoptosis and cell death of cultured keratinocytes stressed by dehydration.
Dementia
Relationship Between Genetic Variants of ACAT1 and APOE with the Susceptibility to Dementia (SADEM Study).
Dermatitis
An isoflavone extract from soybean cake suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis.
Dermatitis
Anti-atopic dermatitis properties of Cordyceps militaris on TNF?/IFN?-stimulated HaCaT cells and experimentally induced atopic dermatitis in mice.
Dermatitis
Rosmarinic acid protects mice from imiquimod induced psoriasis-like skin lesions by inhibiting the IL-23/Th17 axis via regulating Jak2/Stat3 signaling pathway.
Dermatitis
Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2.
Dermatitis
Saussurea lappa alleviates inflammatory chemokine production in HaCaT cells and house dust mite-induced atopic-like dermatitis in Nc/Nga mice.
Dermatitis, Allergic Contact
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1?.
Dermatitis, Allergic Contact
Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease.
Dermatitis, Atopic
Anti-Atopic Dermatitis Effect of Seaweed Fulvescens Extract via Inhibiting the STAT1 Pathway.
Dermatitis, Atopic
Anti-atopic dermatitis properties of Cordyceps militaris on TNF?/IFN?-stimulated HaCaT cells and experimentally induced atopic dermatitis in mice.
Dermatitis, Atopic
Effect of Bifidobacterium infantis on Interferon- gamma- induced keratinocyte apoptosis: a potential therapeutic approach to skin immune abnormalities.
Dermatitis, Atopic
Effect of Neferine on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.
Dermatitis, Atopic
Effects of Deacetylasperulosidic Acid on Atopic Dermatitis through Modulating Immune Balance and Skin Barrier Function in HaCaT, HMC-1, and EOL-1 Cells.
Dermatitis, Atopic
Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis-like skin lesions and TNF-?/IFN-?-induced chemokines production in HaCaT cells.
Dermatitis, Atopic
Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases.
Dermatitis, Atopic
Fas/FasL pathway and cytokines in keratinocytes in atopic dermatitis - Manipulation by the electromagnetic field.
Dermatitis, Atopic
IL-10 augments the IFN-gamma and TNF-alpha induced TARC production in HaCaT cells: a possible mechanism in the inflammatory reaction of atopic dermatitis.
Dermatitis, Atopic
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.
Dermatitis, Atopic
Oral administration of Lactococcus chungangensis inhibits 2,4-dinitrochlorobenzene-induced atopic-like dermatitis in NC/Nga mice.
Dermatitis, Atopic
Psidium guajava extract inhibits thymus and activation-regulated chemokine (TARC/CCL17) production in human keratinocytes by inducing heme oxygenase-1 and blocking NF-?B and STAT1 activation.
Dermatitis, Atopic
Roles of SEA-expressing Staphylococcus aureus, isolated from an atopic dermatitis patient, on expressions of human beta-defensin-2 and inflammatory cytokines in HaCaT cells.
Dermatitis, Atopic
Rosa davurica Pall. improves DNCB-induced atopic dermatitis in mice and regulated TNF-Alpa/IFN-gamma-induced skin inflammatory responses in HaCaT cells.
Dermatitis, Atopic
Saussurea lappa alleviates inflammatory chemokine production in HaCaT cells and house dust mite-induced atopic-like dermatitis in Nc/Nga mice.
Dermatitis, Atopic
Solanum nigrum Linne improves DNCB?induced atopic dermatitis?like skin disease in BALB/c mice.
Dermatitis, Atopic
TGF-beta/Smad signaling inhibits IFN-gamma and TNF-alpha-induced TARC (CCL17) production in HaCaT cells.
Dermatitis, Atopic
The Role of Oxidation in FSL-1 Induced Signaling Pathways of an Atopic Dermatitis Model in HaCaT Keratinocytes.
Dermatitis, Atopic
Umbelliferone reduces the expression of inflammatory chemokines in HaCaT cells and DNCB/DFE-induced atopic dermatitis symptoms in mice.
Dermatitis, Contact
An isoflavone extract from soybean cake suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis.
Dermatitis, Contact
Ethanol Extract of Peanut Sprout Exhibits a Potent Anti-Inflammatory Activity in Both an Oxazolone-Induced Contact Dermatitis Mouse Model and Compound 48/80-Treated HaCaT Cells.
Dermatitis, Contact
Formononetin attenuated allergic diseases through inhibition of epithelial-derived cytokines by regulating E-cadherin.
Dermatitis, Phototoxic
An evaluation of the effects of photoactivation of bithionol, amiodarone and chlorpromazine on human keratinocytes in vitro.
Dermatitis, Phototoxic
Applicability of new degradable hypericin-polymer-conjugates as photosensitizers: principal mode of action demonstrated by in vitro models.
Dermatitis, Phototoxic
Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of new arginine-based surfactant-induced irritation.
Dermatitis, Phototoxic
Controlled Photodynamic Action of Axial Fluorinated DiethoxyP(V)tetrakis(p-methoxyphenyl)porphyrin through Self-Aggregation.
Dermatitis, Phototoxic
Fucoxanthin for Topical Administration, a Phototoxic vs. Photoprotective Potential in a Tiered Strategy Assessed by In Vitro Methods.
Dermatitis, Phototoxic
Implementation of an in vitro methodology for phototoxicity evaluation in a human keratinocyte cell line.
Dermatitis, Phototoxic
Light-induced cytotoxicity of 16 polycyclic aromatic hydrocarbons on the US EPA priority pollutant list in human skin HaCaT keratinocytes: relationship between phototoxicity and excited state properties.
Dermatitis, Phototoxic
Metabolic activation of pyrrolizidine alkaloids leading to phototoxicity and photogenotoxicity in human HaCaT keratinocytes.
Dermatitis, Phototoxic
Nabumetone induced photogenotoxicity mechanism mediated by ROS generation under environmental UV radiation in human keratinocytes (HaCaT) cell line.
Dermatitis, Phototoxic
New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines.
Dermatitis, Phototoxic
Phloxine B phototoxicity: a mechanistic study using HaCaT keratinocytes.
Dermatitis, Phototoxic
Photo-induced reactive oxygen species generation by different water-soluble fullerenes (C) and their cytotoxicity in human keratinocytes.
Dermatitis, Phototoxic
Photosensitization of human skin cell lines by ATMPn (9-acetoxy-2,7,12,17-tetrakis-(beta-methoxyethyl)-porphycene) in vitro: mechanism of action.
Dermatitis, Phototoxic
Phototoxicity of nano titanium dioxides in HaCaT keratinocytes-Generation of reactive oxygen species and cell damage.
Dermatitis, Phototoxic
Phototoxicity of zinc oxide nanoparticles in HaCaT keratinocytes-generation of oxidative DNA damage during UVA and visible light irradiation.
Dermatitis, Phototoxic
Phototoxicity to diuretics and antidiabetics in the cultured keratinocyte cell line HaCaT: evaluation by clonogenic assay and single cell gel electrophoresis Comet assay).
Dermatitis, Phototoxic
Pristine (C60) and hydroxylated [C60(OH)24] fullerene phototoxicity towards HaCaT keratinocytes: type I vs type II mechanisms.
Dermatitis, Phototoxic
Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K2(20), Could Overcome the Photoinstability and Phototoxicity of Vitamin K2(20).
Dermatitis, Phototoxic
Reduction in hypericin-induced phototoxicity by Hypericum perforatum extracts and pure compounds.
Dermatitis, Phototoxic
Titanium Dioxide Induces Apoptosis under UVA Irradiation via the Generation of Lysosomal Membrane Permeabilization-Dependent Reactive Oxygen Species in HaCat Cells.
Dermatitis, Phototoxic
Toxicity evaluation of LQFM048, a novel photoprotective compound synthesized through green chemistry approach.
Diabetes Mellitus
The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA:Cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitro and in vivo.
Diabetes Mellitus, Type 1
A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression.
Diabetes Mellitus, Type 2
Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.
Diabetes Mellitus, Type 2
Effect of corosolic acid on dietary hypercholesterolemia and hepatic steatosis in KK-Ay diabetic mice.
Diabetic Nephropathies
Sterol-O-acyltransferase-1 has a role in kidney disease associated with diabetes and Alport Syndrome.
Drug-Related Side Effects and Adverse Reactions
Anti-cancer Effect of Luminacin, a Marine Microbial Extract, in Head and Neck Squamous Cell Carcinoma Progression via Autophagic Cell Death.
Dry Eye Syndromes
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
Dry Eye Syndromes
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
Dyslipidemias
Acyl-coenzyme A:cholesterol acyltransferase-2 (ACAT-2) is responsible for elevated intestinal ACAT activity in diabetic rats.
Dyslipidemias
Design and Synthesis of A-Ring Simplified Pyripyropene?A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors.
Dyslipidemias
Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.
Dyslipidemias
Structure of the human acyl-CoA:cholesterol acyltransferase-2 (ACAT-2) gene and its relation to dyslipidemia.
Ectodermal Dysplasia
Diverse p63 and p73 isoforms regulate ?133p53 expression through modulation of the internal TP53 promoter activity.
Ectodermal Dysplasia
Mechanistic effect of the human GJB6 gene and its mutations in HaCaT cell proliferation and apoptosis.
Erythema
Dioxinodehydroeckol protects human keratinocyte cells from UVB-induced apoptosis modulated by related genes Bax/Bcl-2 and caspase pathway.
Erythema
Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract.
Fatty Liver
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
Fatty Liver
Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease.
Furunculosis
Defined deletion mutants demonstrate that the major secreted toxins are not essential for the virulence of Aeromonas salmonicida.
Gallstones
ACAT2 and human hepatic cholesterol metabolism: Identification of important gender-related differences in normolipidemic, non-obese Chinese patients.
Gallstones
Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis.
Gallstones
Hepatic acyl-CoA:cholesterol acyltransferase. Development of a standard assay and determination in patients with cholesterol gallstones.
Gallstones
Hepatic acyl-coenzyme A:cholesterol acyltransferase activity is decreased in patients with cholesterol gallstones.
Gallstones
Increased NPC1L1 and ACAT2 expression in the jejunal mucosa from Chinese gallstone patients.
Gallstones
Interruption of the enterohepatic circulation of bile acids stimulates the esterification rate of cholesterol in human liver.
Gallstones
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.
Gas Gangrene
[The influence of AMPs from HaCaT keratinocytes on some bacteria strains derived from skin changes]
Genetic Diseases, Inborn
A Novel Mutation in ACAT1 Causing Beta-Ketothiolase Deficiency in a 4-Year-Old Sri Lankan Boy with Metabolic Ketoacidosis.
Glaucoma, Open-Angle
Gene expression profiles of human trabecular meshwork cells induced by triamcinolone and dexamethasone.
Glioblastoma
Acyl-coenzyme A: Cholesterol acyltransferase inhibitor avasimibe affect survival and proliferation of glioma tumor cell lines.
Glioblastoma
Correction: Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.
Glioblastoma
IL-20 is regulated by hypoxia-inducible factor and up-regulated after experimental ischemic stroke.
Glioblastoma
Induction of intracellular acyl-CoA:cholesterol acyltransferase activity in glioblastoma cells by lidocaine.
Glioblastoma
Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis.
Glioblastoma
K604, a specific acyl?CoA:cholesterol acyltransferase 1 inhibitor, suppresses proliferation of U251?MG glioblastoma cells.
Glioma
Acyl-coenzyme A: Cholesterol acyltransferase inhibitor avasimibe affect survival and proliferation of glioma tumor cell lines.
Glioma
An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
Glioma
Inter-Relationship between Low-Dose Hyper-Radiosensitivity and Radiation-Induced Bystander Effects in the Human T98G Glioma and the Epithelial HaCaT Cell Line.
Graft vs Host Disease
Donor single nucleotide polymorphism in ACAT1 affects the incidence of graft-versus-host disease after bone marrow transplantation.
Granuloma
Influence of the acyl-CoA: cholesterol O-acyltransferase inhibitor, CL 277082, on cholesteryl ester accumulation in rabbit macrophage-rich granulomas and hepatic tissue.
Hand-Foot Syndrome
Local Treatment of Hand-Foot Syndrome with Uridine/Thymidine: In Vitro Appraisal on a Human Keratinocyte Cell Line HaCaT.
Head and Neck Neoplasms
Caesalpinia sappan induces cell death by increasing the expression of p53 and p21WAF1/CIP1 in head and neck cancer cells.
Hepatoblastoma
A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities.
Hepatoblastoma
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
Hepatoblastoma
Cell Type-specific Target Selection by Combinatorial Binding of Smad2/3 Proteins and Hepatocyte Nuclear Factor 4{alpha} in HepG2 Cells.
Hepatomegaly
Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.
Herpes Simplex
Herpes simplex virus type 1 infection has two separate modes of spread in three-dimensional keratinocyte culture.
Herpes Simplex
Human antibodies to herpes simplex virus type 1 glycoprotein C are neutralizing and target the heparan sulfate-binding domain.
Herpes Simplex
In vitro antiviral and immunomodulatory activity of arbidol and structurally related derivatives in herpes simplex virus type 1-infected human keratinocytes (HaCat).
Herpes Simplex
Increased effects of topically applied interferon on herpes simplex virus-induced lesions by caffeine.
Hypercholesterolemia
ACAT inhibitor HL-004 accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats (SHRSP): stimulation of bile acid production by HL-004.
Hypercholesterolemia
ACAT2 is a target for treatment of coronary heart disease associated with hypercholesterolemia.
Hypercholesterolemia
ACAT2 is localized to hepatocytes and is the major cholesterol-esterifying enzyme in human liver.
Hypercholesterolemia
Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.
Hypercholesterolemia
Anti-atherosclerotic properties of the acyl-coenzyme A:cholesterol acyltransferase inhibitor F 12511 in casein-fed New Zealand rabbits.
Hypercholesterolemia
Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate.
Hypercholesterolemia
Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats.
Hypercholesterolemia
Effects of FR145237, an acyl-CoA:cholesterol acyltransferase inhibitor, on diet-induced hypercholesterolemia in diabetic rats.
Hypercholesterolemia
Effects of HMG-CoA reductase inhibition on hepatic expression of key cholesterol-regulatory enzymes and receptors in nephrotic syndrome.
Hypercholesterolemia
Functional characterization of two single nucleotide polymorphisms of acyl-coenzyme A:cholesterol acyltransferase 2.
Hypercholesterolemia
Gemfibrozil reduces non-high-density lipoprotein cholesterol in exogenously hypercholesterolemic (ExHC) rats fed a high-cholesterol diet.
Hypercholesterolemia
Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice.
Hypercholesterolemia
Hepatic acylcoenzyme A: cholesterol acyltransferase activity during diet-induced hypercholesterolemia in cynomolgus monkeys.
Hypercholesterolemia
Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ.
Hypercholesterolemia
Identification of potential ACAT-2 selective inhibitors using pharmacophore, SVM and SVR from Chinese herbs.
Hypercholesterolemia
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A.
Hypercholesterolemia
Imidazolylbenzopyrane derivatives: a new class of acyl-CoA: cholesterol acyltransferase (ACAT) inhibitors.
Hypercholesterolemia
Importance of exogenous cholesterol in diabetic rats: effects of treatment with insulin or with an acyl-CoA:cholesterol acyltransferase inhibitor.
Hypercholesterolemia
Liver-specific inhibition of acyl-coenzyme a:cholesterol acyltransferase 2 with antisense oligonucleotides limits atherosclerosis development in apolipoprotein B100-only low-density lipoprotein receptor-/- mice.
Hypercholesterolemia
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.
Hypercholesterolemia
Mikania micrantha Extract Inhibits HMG-CoA Reductase and ACAT2 and Ameliorates Hypercholesterolemia and Lipid Peroxidation in High Cholesterol-Fed Rats.
Hypercholesterolemia
Molecular structures of human ACAT2 disclose mechanism for selective inhibition.
Hypercholesterolemia
New pyripyropene A derivatives, highly SOAT2-selective inhibitors, improve hypercholesterolemia and atherosclerosis in atherogenic mouse models.
Hypercholesterolemia
Primates highly responsive to dietary cholesterol up-regulate hepatic ACAT2, and less responsive primates do not.
Hypercholesterolemia
pX gene causes hypercholesterolemia in hypercholesterolemia-resistant BALB/c mice.
Hypercholesterolemia
Pyripyropene A, an Acyl-Coenzyme A:Cholesterol Acyltransferase 2-Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia.
Hypercholesterolemia
Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1.
Hypercholesterolemia
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.
Hypercholesterolemia
Sterol Regulatory Element-Binding Proteins, Liver X Receptor, ABCA1 Transporter, CD36, Scavenger Receptors A1 and B1 in Nephrotic Kidney.
Hypercholesterolemia
Systemic Acyl-CoA:cholesterol acyltransferase inhibition reduces inflammation and improves vascular function in hypercholesterolemia.
Hypercholesterolemia
The effect of acyl CoA: cholesterol acyltransferase inhibition on the uptake, esterification and secretion of cholesterol by the hamster small intestine.
Hypercholesterolemia
Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood.
Hypercholesterolemia
Upregulation of acyl-CoA: cholesterol acyltransferase in chronic renal failure.
Hyperglycemia
Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase.
Hyperinsulinism
Comparison of the effect of hyperinsulinemia on acyl-CoA:cholesterol acyltransferase activity in the liver and intestine of the rat.
Hyperinsulinism
Insulin induces human acyl-coenzyme A: cholesterol acyltransferase1 gene expression via MAP kinases and CCAAT/enhancer-binding protein ?.
Hyperlipidemias
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
Hyperlipidemias
Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome.
Hyperlipidemias
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Hyperlipidemias
Effect of SMP-500, a novel acyl-CoA:cholesterol acyltransferase inhibitor, on serum cholesterol level and LDL cholesterol clearance in hamsters with induced hyperlipidemia.
Hyperlipidemias
Effects of a new single-nucleotide polymorphism in the Acyl-CoA:cholesterol acyltransferase-2 gene on plasma lipids and apolipoproteins in patients with hyperlipidemia.
Hyperlipidemias
Expression levels of ACAT1 and ACAT2 genes in the liver and intestine of baboons with high and low lipemic responses to dietary lipids.
Hyperlipidemias
HL-004, the ACAT inhibitor, prevents the progression of atherosclerosis in cholesterol-fed rabbits.
Hyperlipidemias
Identification of Soat1 as a quantitative trait locus gene on mouse chromosome 1 contributing to hyperlipidemia.
Hyperlipidemias
Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes.
Hyperlipidemias
Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages.
Hyperlipidemias
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.
Hyperlipidemias
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro.
Hyperlipidemias
Postprandial hyperlipidemia in Zucker diabetic fatty fa/fa rats, an animal model of type II diabetes, and its amelioration by acyl-CoA:cholesterol acyltransferase inhibition.
Hyperlipidemias
Pyripyropene A, an Acyl-Coenzyme A:Cholesterol Acyltransferase 2-Selective Inhibitor, Attenuates Hypercholesterolemia and Atherosclerosis in Murine Models of Hyperlipidemia.
Hyperlipidemias
The influence of the acyl-CoA:cholesterol acyltransferase-1 gene (-77G-->A) polymorphisms on plasma lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects.
Hyperlipidemias
Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood.
Hyperlipoproteinemia Type III
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hyperlipoproteinemias
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
Hypersensitivity
Cytokine expression in trichloroethylene-induced hypersensitivity dermatitis: an in vivo and in vitro study.
Hypersensitivity
Inter-Relationship between Low-Dose Hyper-Radiosensitivity and Radiation-Induced Bystander Effects in the Human T98G Glioma and the Epithelial HaCaT Cell Line.
Hypertension
Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension.
Hypertension
Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages.
Hypertriglyceridemia
Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential consequences.
Hypertriglyceridemia
High-Fructose Diet-Induced Hypertriglyceridemia Is Associated With Enhanced Hepatic Expression of ACAT2 in Rats.
Hypertriglyceridemia
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
Hypertriglyceridemia
Intestine specific MTP deficiency with global ACAT2 gene ablation lowers acute cholesterol absorption with chylomicrons and high density lipoproteins.
Hypertriglyceridemia
Upregulation of acyl-CoA: cholesterol acyltransferase in chronic renal failure.
Hypertriglyceridemia
[Analysis of acyl-coenzyme A: cholesterol acyltransferase 1 polymorphism in patients with endogenous hypertriglyceridemia in Chinese population]
Hypoalbuminemia
Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome.
Hypoalbuminemia
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Hypoalphalipoproteinemias
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Hypoproteinemia
Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome.
Hypothyroidism
Effects of hypothyroidism and high-fat feeding on mRNA concentrations for the low-density-lipoprotein receptor and on acyl-CoA:cholesterol acyltransferase activities in rat liver.
Ichthyosis
Activation of vascular endothelial growth factor receptor 2 in a cellular model of loricrin keratoderma.
Infections
ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.
Infections
Characterization of chikungunya virus infection of a human keratinocyte cell line: role of mosquito salivary gland protein in suppressing the host immune response.
Infections
Chlamydia pneumoniae disturbs cholesterol homeostasis in human THP-1 macrophages via JNK-PPAR? dependent signal transduction pathways.
Infections
Chlamydia pneumoniae induces macrophage-derived foam cell formation by up-regulating acyl-coenzyme A: cholesterol acyltransferase 1.
Infections
Differential expression of Candida dubliniensis-secreted aspartyl proteinase genes (CdSAP1-4) under different physiological conditions and during infection of a keratinocyte culture.
Infections
Differential gene expression in HaCaT cells may account for the various clinical presentation caused by anthropophilic and geophilic dermatophytes infections.
Infections
Endocytic Internalization of Herpes Simplex Virus 1 in Human Keratinocytes at Low Temperature.
Infections
Evaluation of a Product Containing Xyloglucan and Pea Protein on Skin Barrier Permeability.
Infections
Exploring chitosan nanoparticles as effective inhibitors of antibiotic resistant skin microorganisms - From in vitro to ex vitro testing.
Infections
Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases.
Infections
Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins.
Infections
HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics.
Infections
Hantaan virus can infect human keratinocytes and activate an interferon response through the nuclear translocation of IRF-3.
Infections
Herpes simplex virus type 1 infection has two separate modes of spread in three-dimensional keratinocyte culture.
Infections
Human keratinocyte cultures (HaCaT) can be infected by DENV, triggering innate immune responses that include IFN? and LL37.
Infections
Human Papillomavirus 11 Early Protein E6 Activates Autophagy by Repressing AKT/mTOR and Erk/mTOR.
Infections
Human papillomavirus type 31b infection of human keratinocytes and the onset of early transcription.
Infections
Human papillomavirus type 31b infection of human keratinocytes does not require heparan sulfate.
Infections
Human papillomavirus-16 E7 interacts with Siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes.
Infections
Identification of TRAPPC8 as a host factor required for human papillomavirus cell entry.
Infections
Impact of Rac1 and Cdc42 signaling during early herpes simplex virus type 1 infection of keratinocytes.
Infections
In vitro culture conditions to study keratinocyte differentiation using the HaCaT cell line.
Infections
Increasing prevalence of hypervirulent ST5 methicillin susceptible Staphylococcus aureus subtype poses a serious clinical threat.
Infections
Infection of immortalized human epithelial cell line Hacat with high-concentration Epstein-Barr virus.
Infections
Infectious human papillomavirus type 31b: purification and infection of an immortalized human keratinocyte cell line.
Infections
Inhibition of Tetraspanin Functions Impairs Human Papillomavirus and Cytomegalovirus Infections.
Infections
Innate immune response in human keratinocytes infected by a feline isolate of Malassezia pachydermatis.
Infections
Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection.
Infections
Keratinocyte infection by Actinomadura madurae triggers an inflammatory response.
Infections
Keratinocyte proinflammatory responses to adherent and nonadherent group A streptococci.
Infections
La Crosse Virus Infection of Human Keratinocytes Leads to Interferon-Dependent Apoptosis of Bystander Non-Infected Cells In Vitro.
Infections
Modulation of triglyceride and cholesterol ester synthesis impairs assembly of infectious hepatitis C virus.
Infections
Neutralization of human papillomavirus with monoclonal antibodies reveals different mechanisms of inhibition.
Infections
STING Is Involved in Antiviral Immune Response against VZV Infection via the Induction of Type I and III IFN Pathways.
Infections
Strains of Streptococcus pyogenes from severe invasive infections bind HEp2 and HaCaT cells more avidly than strains from uncomplicated infections.
Infections
Streptolysin O and adherence synergistically modulate proinflammatory responses of keratinocytes to group A streptococci.
Infections
TgROP18 targets IL20RB for host-defense-related-STAT3 activation during Toxoplasma gondii infection.
Infections
The ameliorative effect of hemp seed hexane extracts on the Propionibacterium acnes-induced inflammation and lipogenesis in sebocytes.
Infections
The Herpes simplex virus-induced demise of keratinocytes is associated with a dysregulated pattern of p63 expression.
Infections
The orthopoxvirus 68k ankyrin-like protein is essential for DNA replication and complete gene expression of modified vaccinia virus Ankara in non-permissive human and murine cells.
Infections
The Short Lipopeptides (C10)2-KKKK-NH2 and (C12)2-KKKK-NH2 Protect HaCaT Keratinocytes from Bacterial Damage Caused by Staphylococcus aureus Infection in a Co-Culture Model.
Infections
Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line.
Infections
Vimentin Modulates Infectious Internalization of Human Papillomavirus 16 Pseudovirions.
Infections
Water-based extracts of Zizania latifolia inhibit Staphylococcus aureus infection through the induction of human beta-defensin 2 expression in HaCaT cells.
Infections
[Chlamydia pneumoniae induces THP-1-derived foam cell formation by up-regulating the expression of acyl-coenzyme A: cholesterol acyltransferase 1]
Insulin Resistance
Cholesterol and fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.
Insulin Resistance
Multi-Omics Analysis to Examine Gene Expression and Metabolites From Multisite Adipose-Derived Mesenchymal Stem Cells.
Insulin Resistance
Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.
Insulin Resistance
Pharmacological inhibition of acyl-coenzyme A:cholesterol acyltransferase alleviates obesity and insulin resistance in diet-induced obese mice by regulating food intake.
Insulin Resistance
Potential Clinical Implications of the Urotensin II Receptor Antagonists.
Insulin Resistance
Sterol O-acyltransferase 1 deficiency improves defective insulin signaling in the brains of mice fed a high-fat diet.
Keratosis, Actinic
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Keratosis, Actinic
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Ketosis
A Novel Mutation in ACAT1 Causing Beta-Ketothiolase Deficiency in a 4-Year-Old Sri Lankan Boy with Metabolic Ketoacidosis.
Ketosis
Clinical presentation and outcome in a series of 32 patients with 2-methylacetoacetyl-coenzyme A thiolase (MAT) deficiency.
Ketosis
Genome-wide association study and functional analyses for clinical and subclinical ketosis in Holstein cattle.
Ketosis
The recent insights into the function of ACAT1: A possible anti-cancer therapeutic target.
Kidney Failure, Chronic
F(2)-isoprostanes: sensitive biomarkers of oxidative stress in vitro and in vivo: a gas chromatography-mass spectrometric approach.
Kidney Failure, Chronic
Upregulation of acyl-CoA: cholesterol acyltransferase in chronic renal failure.
Latent Infection
Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression.
Lecithin Cholesterol Acyltransferase Deficiency
ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure.
Lecithin Cholesterol Acyltransferase Deficiency
ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.
Lecithin Cholesterol Acyltransferase Deficiency
Demonstration of intact intracellular cholesterol esterification and normal low-density lipoprotein pathway in fibroblasts from a patient with lecithin:cholesterol acyltransferase deficiency.
Lecithin Cholesterol Acyltransferase Deficiency
Detection of heterozygotes for familial lecithin: cholesterol acyltransferase (LCAT) deficiency.
Lecithin Cholesterol Acyltransferase Deficiency
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Leprosy
Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: new frontiers in the cellular immunology of leprosy.
Leukemia
Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes.
Leukemia
Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes.
Leukemia
Induction of differentiation-associated changes in established human cells by infection with adeno-associated virus type 2.
Leukemia
Low level laser irradiation stimulates mitochondrial membrane potential and disperses subnuclear promyelocytic leukemia protein.
Leukemia
Oxidative DNA damage induced by visible light in mammalian cells: extent, inhibition by antioxidants and genotoxic effects.
Leukemia
Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane.
Leukemia
Selected Compounds Structurally Related to Acyclic Sesquiterpenoids and Their Antibacterial and Cytotoxic Activity.
Leukemia, Erythroblastic, Acute
Cholesterol esterification during differentiation of mouse erythroleukemia (Friend) cells.
Leukemia, T-Cell
[Differences of Nonsense-Mediated mRNA Degradation Activity in Mammalian Cell Lines Revealed by a Fluorescence Reporter].
Leukocytosis
Acat1 gene ablation in mice increases hematopoietic progenitor cell proliferation in bone marrow and causes leukocytosis.
Leukocytosis
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
Lichen Planus
Possible treatment for cutaneous lichen planus: An in vitro anti-inflammatory role of Angelica polysaccharide in human keratinocytes HaCaT.
Lichen Planus
RETRACTION NOTICE: Possible treatment for cutaneous lichen planus: An in vitro anti-inflammatory role of Angelica polysaccharide in human keratinocytes HaCaT.
Liver Cirrhosis
Acyl-CoA:cholesterol acyltransferase 1 mediates liver fibrosis by regulating free cholesterol accumulation in hepatic stellate cells.
Liver Cirrhosis
Downregulation of Acat1 by miR-21 may participate in liver fibrosis upon chronic DDT exposure.
Liver Diseases
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
Liver Diseases
Niemann-Pick C1-deficient mice lacking sterol O-acyltransferase 2 have less hepatic cholesterol entrapment and improved liver function.
Liver Diseases
Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease.
Liver Diseases
Serum cholesterol esterification in liver disease. Combined determinations of lecithin: cholesterol acyltransferase and lipoprotein-X.
Liver Neoplasms
Long non-coding RNA HULC promotes UVB-induced injury by up-regulation of BNIP3 in keratinocytes.
Lung Neoplasms
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
Lung Neoplasms
Blocking mutation independent p53 aggregation by emodin modulates autophagic cell death pathway in lung cancer.
Lung Neoplasms
Effect of inhibiting ACAT-1 expression on the growth and metastasis of Lewis lung carcinoma.
Lung Neoplasms
Efficient hydrolytic cleavage of DNA and antiproliferative effect on human cancer cells by two dinuclear Cu(II) complexes containing a carbohydrazone ligand and 1,10-phenanthroline as a coligand.
Lung Neoplasms
Pharmacological importance, characterization and applications of gold and silver nanoparticles synthesized by Panax ginseng fresh leaves.
Lung Neoplasms
Phoyunnanin E inhibits migration of non-small cell lung cancer cells via suppression of epithelial-to-mesenchymal transition and integrin ?v and integrin ?3.
Lung Neoplasms
Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator.
Lung Neoplasms
The wound-healing effect of 7,3',4'-trimethoxyflavone through increased levels of prostaglandin E2 by 15-hydroxyprostaglandin dehydrogenase inhibition.
Lymphatic Metastasis
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer.
Lymphatic Metastasis
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.
Macular Degeneration
Retinal hypercholesterolemia triggers cholesterol accumulation and esterification in photoreceptor cells.
Macular Degeneration
Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration.
matriptase deficiency
Matriptase Regulates Proliferation and Early, but Not Terminal, Differentiation of Human Keratinocytes.
Melanoma
A lectin from Bothrops leucurus snake venom raises cytosolic calcium levels and promotes B16-F10 melanoma necrotic cell death via mitochondrial permeability transition.
Melanoma
A Multifunctional and Possible Skin UV Protectant, (3R)-5-Hydroxymellein, Produced by an Endolichenic Fungus Isolated from Parmotrema austrosinense.
Melanoma
Achillea millefolium L. and Achillea biebersteinii Afan. Hydroglycolic Extracts-Bioactive Ingredients for Cosmetic Use.
Melanoma
Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma.
Melanoma
Alpha-melanocyte-stimulating hormone reduces impact of proinflammatory cytokine and peroxide-generated oxidative stress on keratinocyte and melanoma cell lines.
Melanoma
Antitumorigenic effect of insect-derived peptide poecilocorisin-1 in human skin cancer cells through regulation of Sp1 transcription factor.
Melanoma
Assessment of the Antimicrobial, Antioxidant, and Antiproliferative Potential of Sideritisraeseri subps. raeseri Essential Oil.
Melanoma
Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.
Melanoma
Betulinic acid induces apoptosis in skin cancer cells and differentiation in normal human keratinocytes.
Melanoma
Biological Evaluation of Black Chokeberry Extract Free and Embedded in Two Mesoporous Silica-Type Matrices.
Melanoma
Cell cycle progression data on human skin cancer cells with anticancer synthetic peptide LTX-315 treatment.
Melanoma
Combination of PDT and inhibitor treatment affects melanoma cells and spares keratinocytes.
Melanoma
Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression.
Melanoma
Efficacy of Concanavalin-A conjugated nanotransfersomal gel of apigenin for enhanced targeted delivery of UV induced skin malignant melanoma.
Melanoma
Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol.
Melanoma
Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier.
Melanoma
Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53.
Melanoma
Fabrication, in-vitro characterization, and enhanced in-vivo evaluation of carbopol-based nanoemulsion gel of apigenin for UV-induced skin carcinoma.
Melanoma
Free-Radical-Scavenging, Antityrosinase, and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavones.
Melanoma
Hantaan virus can infect human keratinocytes and activate an interferon response through the nuclear translocation of IRF-3.
Melanoma
Hypericin photodynamic activity in DPPC liposomes - part II: stability and application in melanoma B16-F10 cancer cells.
Melanoma
Identification of functional platelet-activating factor receptors on human keratinocytes.
Melanoma
Imaging and detection of cell apoptosis byIn vitrophotodynamic therapy applications of zinc (II) phthalocyanine on human melanoma cancer.
Melanoma
Insights into ZIKV-Mediated Innate Immune Responses in Human Dermal Fibroblasts and Epidermal Keratinocytes.
Melanoma
Intracellular calcium measurements of single human skin cells after stimulation with corticotropin-releasing factor and urocortin using confocal laser scanning microscopy.
Melanoma
Keratinocyte-derived Laminin-332 Promotes Adhesion and Migration in Melanocytes and Melanoma.
Melanoma
Keratinocytes negatively regulate the N-cadherin levels of melanoma cells via contact-mediated calcium regulation.
Melanoma
KGF Promotes Paracrine Activation of the SCF/c-KIT Axis from Human Keratinocytes to Melanoma Cells.
Melanoma
Label-free and non-invasive discrimination of HaCaT and melanoma cells in a co-culture model by hyperspectral confocal reflectance microscopy.
Melanoma
Mechanism of miR-137 regulating migration and invasion of melanoma cells by targeting PIK3R3 gene.
Melanoma
Mechanisms of Tanshinone II a inhibits malignant melanoma development through blocking autophagy signal transduction in A375 cell.
Melanoma
Mechanistic investigations of antitumor activity of a Rhodamine B?oleanolic acid derivative bioconjugate.
Melanoma
Melanoma cell surface-expressed phosphatidylserine as a therapeutic target for cationic anticancer peptide, temporin-1CEa.
Melanoma
MicroRNA-9 inhibits the proliferation and migration of malignant melanoma cells via targeting sirituin 1.
Melanoma
Mitochondrial expression of the two-pore domain TASK-3 channels in malignantly transformed and non-malignant human cells.
Melanoma
Neurotensin receptor1 antagonist SR48692 reduces proliferation by inducing apoptosis and cell cycle arrest in melanoma cells.
Melanoma
Non-covalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI-1.
Melanoma
Nootkatol prevents ultraviolet radiation-induced photoaging via ORAI1 and TRPV1 inhibition in melanocytes and keratinocytes.
Melanoma
Ov-16 [4-(3,4-dihydroxybenzoyloxymethyl)phenyl-O-?-D-glucopyranoside] inhibits melanin synthesis by regulating expressions of melanogenesis-regulated gene and protein.
Melanoma
PCTAIRE1 regulates p27 stability, apoptosis and tumor growth in malignant melanoma.
Melanoma
Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.
Melanoma
Potent USP10/13 antagonist spautin-1 suppresses melanoma growth via ROS-mediated DNA damage and exhibits synergy with cisplatin.
Melanoma
Preparation, Drug Treatment, and Immunohistological Analysis of Tri-Culture Spheroid 3D Melanoma-Like Models.
Melanoma
Relative In Vitro Potentials of Parthenolide to Induce Apoptosis and Cell Cycle Arrest in Skin Cancer Cells.
Melanoma
Rosa platyacantha Schrenk from Kazakhstan-Natural Source of Bioactive Compounds with Cosmetic Significance.
Melanoma
Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor.
Melanoma
Selected Compounds Structurally Related to Acyclic Sesquiterpenoids and Their Antibacterial and Cytotoxic Activity.
Melanoma
SiO2-PVA-Fe(acac)3 Hybrid Based Superparamagnetic Nanocomposites for Nanomedicine: Morpho-textural Evaluation and In Vitro Cytotoxicity Assay.
Melanoma
Synthesis and photochemical transformation of 3?,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity.
Melanoma
Synthetic Peptide ?M4-Induced Cell Death Associated with Cytoplasmic Membrane Disruption, Mitochondrial Dysfunction and Cell Cycle Arrest in Human Melanoma Cells.
Melanoma
Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth.
Melanoma
tert-Butylphenolic Derivatives from Paenibacillus odorifer-A Case of Bioconversion.
Melanoma
Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity.
Melanoma
The anti-melanogenic effects of ellagic acid through induction of autophagy in melanocytes and suppression of UVA-activated ?-MSH pathways via Nrf2 activation in keratinocytes.
Melanoma
The antimicrobial peptide human cationic antimicrobial protein-18/cathelicidin LL-37 as a putative growth factor for malignant melanoma.
Melanoma
The Comparison of In Vitro Photosensitizing Efficacy of Curcumin-Loaded Liposomes Following Photodynamic Therapy on Melanoma MUG-Mel2, Squamous Cell Carcinoma SCC-25, and Normal Keratinocyte HaCaT Cells.
Melanoma
The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT).
Melanoma
The mechanism of melanocytes-specific cytotoxicity induced by phenol compounds having a prooxidant effect, relating to the appearance of leukoderma.
Melanoma
The Phytochemical Analysis of Vinca L. Species Leaf Extracts Is Correlated with the Antioxidant, Antibacterial, and Antitumor Effects.
Melanoma
The Protective Effects of EMF-LTE against DNA Double-Strand Break Damage In Vitro and In Vivo.
Melanoma
The Quinone Methide Aurin Is a Heat Shock Response Inducer That Causes Proteotoxic Stress and Noxa-dependent Apoptosis in Malignant Melanoma Cells.
Melanoma
The Skin-Whitening Effects of Ectoine via the Suppression of ?-MSH-Stimulated Melanogenesis and the Activation of Antioxidant Nrf2 Pathways in UVA-Irradiated Keratinocytes.
Melanoma
Transcutaneous delivery of leflunomide nanoemulgel: Mechanistic investigation into physicomechanical characteristics, in vitro anti-psoriatic and anti-melanoma activity.
Melanoma
UV-B-activated B16 melanoma cells or HaCaT keratinocytes accelerate signaling pathways associated with melanogenesis via ANGPTL 2 induction, an activity antagonized by Chrysanthemum extract.
Melanoma
Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core-Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells.
Melanoma, Amelanotic
Photothermal sensitisation as a novel therapeutic approach for tumours: studies at the cellular and animal level.
Melanoma, Experimental
Effect of heterocyclic pyrimidine compounds on UVB-induced cell damage in human keratinocytes and on melanogenesis in mouse B16 cells.
Melanoma, Experimental
N-acetylglucosamine microemulsions: Assessment of skin penetration, cytotoxicity, and anti-melanogenesis.
Melanoma, Experimental
UV-B-activated B16 melanoma cells or HaCaT keratinocytes accelerate signaling pathways associated with melanogenesis via ANGPTL 2 induction, an activity antagonized by Chrysanthemum extract.
Mesothelioma, Malignant
Antiproliferative Effects on Tumour Cells and Promotion of Keratinocyte Wound Healing by Different Lichen Compounds.
Mesothelioma, Malignant
HPLC-FLD determination of NBD-cholesterol, its ester and other metabolites in cellular lipid extracts.
Metabolic Diseases
Sterol O-acyltransferase 1 deficiency improves defective insulin signaling in the brains of mice fed a high-fat diet.
Mouth Neoplasms
Luteolin Impacts on the DNA Damage Pathway in Oral Squamous Cell Carcinoma.
Myocardial Infarction
The myocardial infarct size-limiting and antiarrhythmic effects of acyl-CoA:Cholesterol acyltransferase inhibitor VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against ischaemia/reperfusion injury both in vitro and in vivo.
Nasal Polyps
Expression of human beta-defensin-1 promotes differentiation of keratinocytes.
Neoplasm Metastasis
Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer.
Neoplasm Metastasis
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer.
Neoplasm Metastasis
AGR2-mediated lung adenocarcinoma metastasis novel mechanism network through repression with interferon coupling cytoskeleton to steroid metabolism-dependent humoral immune response.
Neoplasm Metastasis
Cell death induced by N-(4-hydroxyphenyl)retinamide in human epidermal keratinocytes is modulated by TGF-beta and diminishes during the progression of squamous cell carcinoma.
Neoplasm Metastasis
Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis.
Neoplasm Metastasis
Effect of inhibiting ACAT-1 expression on the growth and metastasis of Lewis lung carcinoma.
Neoplasm Metastasis
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.
Neoplasm Metastasis
MicroRNA-17-3p promotes keratinocyte cells growth and metastasis via targeting MYOT and regulating Notch1/NF-?B pathways.
Neoplasm Metastasis
Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs).
Neoplasm Metastasis
Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.
Neoplasm Metastasis
Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor ? Superfamily Type 1 Receptors.
Neoplasm Metastasis
Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Neoplasms
"Trans-differentiation" from epidermal to mesenchymal/myogenic phenotype is associated with a drastic change in cell-cell and cell-matrix adhesion molecules.
Neoplasms
(+)-Nootkatone inhibits tumor necrosis factor ?/interferon ?-induced production of chemokines in HaCaT cells.
Neoplasms
(2S)-2?-methoxykurarinone from Sophora flavescens suppresses cutaneous T cell-attracting chemokine/CCL27 expression induced by interleukin-ß/tumor necrosis factor-? via heme oxygenase-1 in human keratinocytes.
Neoplasms
1alpha,25-dihydroxyvitamin D3 induces sphingomyelin hydrolysis in HaCaT cells via tumor necrosis factor alpha.
Neoplasms
2,3-Dimethoxy-2'-hydroxychalcone ameliorates TNF-?-induced ICAM-1 expression and subsequent monocyte adhesiveness via NF-kappaB inhibition and HO-1 induction in HaCaT cells.
Neoplasms
A GPR40 agonist GW9508 suppresses CCL5, CCL17, and CXCL10 induction in keratinocytes and attenuates cutaneous immune inflammation.
Neoplasms
A Novel Near-infrared Fluorescent Probe TMTP1-PEG4-ICG for in vivo Tumor Imaging.
Neoplasms
A specific cholesterol metabolic pathway is established in a subset of HCCs for tumor growth.
Neoplasms
A synthetic peptide blocking TRPV1 activation inhibits UV-induced skin responses.
Neoplasms
A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.
Neoplasms
Aberrantly Expressed Genes in HaCaT Keratinocytes Chronically Exposed to Arsenic Trioxide.
Neoplasms
Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7.
Neoplasms
Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer.
Neoplasms
ACAT2 Promotes Cell Proliferation and Associates with Malignant Progression in Colorectal Cancer.
Neoplasms
Achillea millefolium L. and Achillea biebersteinii Afan. Hydroglycolic Extracts-Bioactive Ingredients for Cosmetic Use.
Neoplasms
Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.
Neoplasms
Acyl-coenzyme A: Cholesterol acyltransferase inhibitor avasimibe affect survival and proliferation of glioma tumor cell lines.
Neoplasms
Alantolactone from Saussurea lappa Exerts Antiinflammatory Effects by Inhibiting Chemokine Production and STAT1 Phosphorylation in TNF-? and IFN-?-induced in HaCaT cells.
Neoplasms
Allopurinol suppresses expression of the regulatory T-cell migration factors TARC/CCL17 and MDC/CCL22 in HaCaT keratinocytes via restriction of nuclear factor-?B activation.
Neoplasms
Alloreactive microenvironment after human hematopoietic cell transplantation induces genomic alterations in epithelium through an ROS-mediated mechanism: in vivo and in vitro study and implications to secondary neoplasia.
Neoplasms
Alpha-melanocyte-stimulating hormone reduces impact of proinflammatory cytokine and peroxide-generated oxidative stress on keratinocyte and melanoma cell lines.
Neoplasms
An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
Neoplasms
Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes.
Neoplasms
Anti-allergic effects of sesquiterpene lactones from the root of Aucklandia lappa Decne.
Neoplasms
Anti-Apoptotic NF-?B and "Gain of Function" mutp53 in Concert Act Pro-Apoptotic in Response to UVB+IL-1 via Enhanced TNF Production.
Neoplasms
Anti-apoptotic role of EGF in HaCaT keratinocytes via a PPARbeta-dependent mechanism.
Neoplasms
Anti-Atopic Dermatitis Effect of Seaweed Fulvescens Extract via Inhibiting the STAT1 Pathway.
Neoplasms
Anti-cancer effects of cerium oxide nanoparticles and its intracellular redox activity.
Neoplasms
Anti-inflammatory Actions of Herbal Formula Gyejibokryeong-Hwan Regulated by Inhibiting Chemokine Production and STAT1 Activation in HaCaT Cells.
Neoplasms
Anti-Inflammatory Effect of Chloroform Fraction of Pyrus Ussuriensis Maxim. Leaf Extract on 2, 4-Dinitrochlorobenzene-Induced Atopic Dermatitis in nc/nga Mice.
Neoplasms
Anti-inflammatory Effects of Achillea millefolium on Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice.
Neoplasms
Anti-Inflammatory Effects of Compounds from Cudrania tricuspidata in HaCaT Human Keratinocytes.
Neoplasms
Anti-inflammatory effects of ethanol extract from the leaves and shoots of Cedrela odorata L. in cytokine-stimulated keratinocytes.
Neoplasms
Anti-inflammatory effects of Perillae Herba ethanolic extract against TNF-?/IFN-?-stimulated human keratinocyte HaCaT cells.
Neoplasms
Anti-inflammatory effects of Sanguisorbae Radix water extract on the suppression of mast cell degranulation and STAT-1/Jak-2 activation in BMMCs and HaCaT keratinocytes.
Neoplasms
Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis.
Neoplasms
Anti-Inflammatory, Barrier-Protective, and Antiwrinkle Properties of Agastache rugosa Kuntze in Human Epidermal Keratinocytes.
Neoplasms
Anti-MRSA-acting carbamidocyclophanes H-L from the Vietnamese cyanobacterium Nostoc sp. CAVN2.
Neoplasms
Anti?inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF??B pathway.
Neoplasms
Anticancer effects of alloxanthoxyletin and fatty acids esters - In vitro study on cancer HTB-140 and A549 cells.
Neoplasms
Anticancer properties of low molecular weight oat beta-glucan An in vitro study.
Neoplasms
Antioxidative, anti-inflammatory, and matrix metalloproteinase inhibitory activities of 20(S)-ginsenoside Rg3 in cultured mammalian cell lines.
Neoplasms
Antiproliferative, cytotoxic and apoptotic activity of the bentonite transformation of sesquiterpene lactone glaucolide B to 5?-hydroxy-hirsutinolide on tumor cell lines.
Neoplasms
Antipsoriatic effects of avarol-3'-thiosalicylate are mediated by inhibition of TNF-alpha generation and NF-kappaB activation in mouse skin.
Neoplasms
Apoptosis and cytokine release induced by ionizing or ultraviolet B radiation in primary and immortalized human keratinocytes.
Neoplasms
Applicability of new degradable hypericin-polymer-conjugates as photosensitizers: principal mode of action demonstrated by in vitro models.
Neoplasms
Applying Quality by Design Principles in the Development and Preparation of a New Radiopharmaceutical: Technetium-99m-Imatinib Mesylate.
Neoplasms
Arazyme inhibits cytokine expression and upregulates skin barrier protein expression.
Neoplasms
Aromadendrene oxide 2, induces apoptosis in skin epidermoid cancer cells through ROS mediated mitochondrial pathway.
Neoplasms
Artemisia anomala Herba Alleviates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice and the Production of Pro-Inflammatory Mediators in Tumor Necrosis Factor Alpha-/Interferon Gamma-Induced HaCaT Cells.
Neoplasms
Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation.
Neoplasms
Ashwagandha root extract exerts anti?inflammatory effects in HaCaT cells by inhibiting the MAPK/NF??B pathways and by regulating cytokines.
Neoplasms
Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression-An in vitro study.
Neoplasms
Assessment of the Antimicrobial, Antioxidant, and Antiproliferative Potential of Sideritisraeseri subps. raeseri Essential Oil.
Neoplasms
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.
Neoplasms
Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice.
Neoplasms
Aster glehni Extract Containing Caffeoylquinic Compounds Protects Human Keratinocytes through the TRPV4-PPAR?-AMPK Pathway.
Neoplasms
Avasimibe Encapsulated in Human Serum Albumin Blocks Cholesterol Esterification for Selective Cancer Treatment.
Neoplasms
Avasimibe inhibits the proliferation, migration and invasion of glioma cells by suppressing linc00339.
Neoplasms
Bacillus thuringiensis toxins are cytotoxic to cervical cancer (HeLa) but not to breast cancer (MCF7) cells.
Neoplasms
Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor ? (TNF-?) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-?B) Signaling Pathway.
Neoplasms
Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha and 1 alpha, 25-dihydroxyvitamin D(3).
Neoplasms
Bifunctional alkylating agent-induced p53 and nonclassical nuclear factor kappaB responses and cell death are altered by caffeic acid phenethyl ester: a potential role for antioxidant/electrophilic response-element signaling.
Neoplasms
Biological Evaluation of Black Chokeberry Extract Free and Embedded in Two Mesoporous Silica-Type Matrices.
Neoplasms
Biotinylated PAMAM G3 dendrimer conjugated with celecoxib and/or Fmoc-l-Leucine and its cytotoxicity for normal and cancer human cell lines.
Neoplasms
Biseokeaniamides A, B, and C, Sterol O-Acyltransferase Inhibitors from an Okeania sp. Marine Cyanobacterium.
Neoplasms
Blocking ACAT-1 Activity for Tumor Therapy with Fluorescent Hyperstar Polymer-Encapsulated Avasimible.
Neoplasms
Bone morphogenetic protein antagonist noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways.
Neoplasms
Camptothecin Fails to Induce Apoptosis in Tumor Necrosis Factor-Alpha-Treated HaCaT Cells.
Neoplasms
CCL28 production in HaCaT cells was mediated by different signal pathways from CCL27.
Neoplasms
CD44-expressing undifferentiated carcinoma with rhabdoid features of the pancreas: Molecular analysis of aggressive invasion and metastasis.
Neoplasms
CD44v6 expression in human skin keratinocytes as a possible mechanism for carcinogenesis associated with chronic arsenic exposure.
Neoplasms
Cell death induced by N-(4-hydroxyphenyl)retinamide in human epidermal keratinocytes is modulated by TGF-beta and diminishes during the progression of squamous cell carcinoma.
Neoplasms
Characterization and differentiation-dependent regulation of secreted phospholipases A in human keratinocytes and in healthy and psoriatic human skin.
Neoplasms
Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds.
Neoplasms
Chemical composition of the essential oil from the leaves of Anaxagorea brevipes (Annonaceae) and evaluation of its bioactivity.
Neoplasms
Chemopreventive Activity of Polyphenolics from Black Jamapa Bean (Phaseolus vulgaris L.) on HeLa and HaCaT Cells.
Neoplasms
Chijabyukpi-Tang Inhibits Pro-Inflammatory Cytokines and Chemokines via the Nrf2/HO-1 Signaling Pathway in TNF-?/IFN-?-Stimulated HaCaT Cells and Ameliorates 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions in Mice.
Neoplasms
Chlorin-PEI-labeled cellulose nanocrystals: synthesis, characterization and potential application in PDT.
Neoplasms
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Neoplasms
Chungsimyeonja-eum inhibits inflammatory responses in RAW 264.7 macrophages and HaCaT keratinocytes.
Neoplasms
CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.
Neoplasms
Cold atmospheric plasma ameliorates imiquimod-induced psoriasiform dermatitis in mice by mediating antiproliferative effects.
Neoplasms
Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta.
Neoplasms
Combination cisplatin and sulforaphane treatment reduces proliferation, invasion, and tumor formation in epidermal squamous cell carcinoma.
Neoplasms
Comparative effects of UV A and UV B on clonogenic survival and delayed cell death in skin cell lines from humans and fish.
Neoplasms
Comparative sensitivity of tumor and non-tumor cell lines as a reliable approach for in vitro cytotoxicity screening of lysine-based surfactants with potential pharmaceutical applications.
Neoplasms
Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation.
Neoplasms
Constitutive expression of G-CSF and GM-CSF in human skin carcinoma cells with functional consequence for tumor progression.
Neoplasms
Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the progression of skin carcinoma cells.
Neoplasms
Corn silk extract improves cholesterol metabolism in C57BL/6J mouse fed high-fat diets.
Neoplasms
Cytotoxic Activity of Bioactive Compound 1, 2- Benzene Dicarboxylic Acid, Mono 2- Ethylhexyl Ester Extracted from a Marine Derived Streptomyces sp. VITSJK8.
Neoplasms
Cytotoxic, tubulin-interfering and proapoptotic activities of 4'-methylthio-trans-stilbene derivatives, analogues of trans-resveratrol.
Neoplasms
Cytotoxicity of citral against melanoma cells: The involvement of oxidative stress generation and cell growth protein reduction.
Neoplasms
Deep Eutectic Solvents and Nonconventional Technologies for Blueberry-Peel Extraction: Kinetics, Anthocyanin Stability, and Antiproliferative Activity.
Neoplasms
Defects of basement membrane and hemidesmosome structure correlate with malignant phenotype and stromal interactions in HaCaT-Ras xenografts.
Neoplasms
Dehydroxymethylepoxyquinomicin suppresses atopic dermatitis-like lesions in a stratum corneum-removed murine model through NF-?B inhibition.
Neoplasms
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Neoplasms
Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones.
Neoplasms
Deoxynivalenol induced mouse skin tumor initiation: Elucidation of molecular mechanisms in human HaCaT keratinocytes.
Neoplasms
Development of Parvifloron D-loaded Smart Nanoparticles to Target Pancreatic Cancer.
Neoplasms
Dictamnine delivered by PLGA nanocarriers ameliorated inflammation in an oxazolone-induced dermatitis mouse model.
Neoplasms
Differential patterns of stromelysin-2 (MMP-10) and MT1-MMP (MMP-14) expression in epithelial skin cancers.
Neoplasms
Differential regulation of IL-1 and IL-1 receptor antagonist in HaCaT keratinocytes by tumor necrosis factor-alpha and transforming growth factor-beta 1.
Neoplasms
Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide.
Neoplasms
Differential regulation of thymus- and activation-regulated chemokine induced by IL-4, IL-13, TNF-alpha and IFN-gamma in human keratinocyte and fibroblast.
Neoplasms
Dihydroartemisinin Alleviates Imiquimod-Induced Psoriasis-like Skin Lesion in Mice Involving Modulation of IL-23/Th17 Axis.
Neoplasms
Discovering pH triggered charge rebound surface modulated topical nanotherapy against aggressive skin papilloma.
Neoplasms
Disentangling the Complexity of a Hexa-Herbal Chinese Medicine Used for Inflammatory Skin Conditions-Predicting the Active Components by Combining LC-MS-Based Metabolite Profiles and in vitro Pharmacology.
Neoplasms
Disrupting cholesterol esterification by bitter melon suppresses triple-negative breast cancer cell growth.
Neoplasms
Distinct progression-associated expression of tumor and stromal MMPs in HaCaT skin SCCs correlates with onset of invasion.
Neoplasms
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation.
Neoplasms
Double-Stranded RNA Induces MMP-9 Gene Expression in HaCaT Keratinocytes by Tumor Necrosis Factor-?
Neoplasms
Dysregulation of Ketone Body Metabolism Is Associated With Poor Prognosis for Clear Cell Renal Cell Carcinoma Patients.
Neoplasms
E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.
Neoplasms
Eckol from Ecklonia cava ameliorates TNF-?/IFN-?-induced inflammatory responses via regulating MAPKs and NF-?B signaling pathway in HaCaT cells.
Neoplasms
Effect of heterocyclic pyrimidine compounds on UVB-induced cell damage in human keratinocytes and on melanogenesis in mouse B16 cells.
Neoplasms
Effect of inhibiting ACAT-1 expression on the growth and metastasis of Lewis lung carcinoma.
Neoplasms
Effect of tumor necrosis factor-alpha on acyl coenzyme A: cholesteryl acyltransferase activity and ACAT1 gene expression in THP-1 macrophages.
Neoplasms
Effect of yerba mate (Ilex paraguariensis) tea on topoisomerase inhibition and oral carcinoma cell proliferation.
Neoplasms
Effects of the 24 N-terminal amino acids of p55PIK on endotoxinstimulated release of inflammatory cytokines by hacat cells.
Neoplasms
Effects of topical application of a tri-herb formula on inflammatory dry-skin condition in mice with oxazolone-induced atopic dermatitis.
Neoplasms
Eicosapentaenoic acid inhibits UV-induced MMP-1 expression in human dermal fibroblasts.
Neoplasms
Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines.
Neoplasms
Enhanced Antipsoriatic Activity of Mycophenolic Acid Against the TNF-?-Induced HaCaT Cell Proliferation by Conjugated Poloxamer Micelles.
Neoplasms
Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.
Neoplasms
Enhanced expression of cyclooxygenase (COX)-2 in human skin epidermal cancer cells: evidence for growth suppression by inhibiting COX-2 expression.
Neoplasms
Enhanced serum interferon-lambda 1 interleukin-29 levels in patients with psoriasis vulgaris.
Neoplasms
Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis.
Neoplasms
Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt.
Neoplasms
Eupatilin with PPAR? agonistic effects inhibits TNF?-induced MMP signaling in HaCaT cells.
Neoplasms
Evaluation of Antiproliferative Effect of N-(alkyladamantyl)phthalimides In vitro.
Neoplasms
Expression of human macrophage metalloelastase (MMP-12) by tumor cells in skin cancer.
Neoplasms
Expression of laminin 5 by parental and c-Ha-ras-transformed HaCaT keratinocytes in organotypic cultures.
Neoplasms
Expression of MHC Class II, CD70, CD80, CD86 and pro-inflammatory cytokines is differentially regulated in oral epithelial cells following bacterial challenge.
Neoplasms
Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.
Neoplasms
Extracellular synthesis of gold nanoparticles using the marine bacterium Paracoccus haeundaensis BC74171T and evaluation of their antioxidant activity and antiproliferative effect on normal and cancer cell lines.
Neoplasms
FasL and TRAIL induce epidermal apoptosis and skin ulceration upon exposure to Leishmania major.
Neoplasms
FGF-7 facilitates the process of psoriasis by inducing TNF-? expression in HaCaT cells.
Neoplasms
Fibroblast growth factor-binding protein expression changes with disease progression in clinical and experimental human squamous epithelium.
Neoplasms
Fractionated Coptis chinensis Extract and Its Bioactive Component Suppress Propionibacterium acnes-Stimulated Inflammation in Human Keratinocytes.
Neoplasms
Furylhydroquinones and miscellaneous compounds from the roots of Lithospermum erythrorhizon and their anti-inflammatory effect in HaCaT cells.
Neoplasms
G-protein-coupled receptor GPR49 is up-regulated in basal cell carcinoma and promotes cell proliferation and tumor formation.
Neoplasms
Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63.
Neoplasms
Gardenia jasminoides Extract Attenuates the UVB-Induced Expressions of Cytokines in Keratinocytes and Indirectly Inhibits Matrix Metalloproteinase-1 Expression in Human Dermal Fibroblasts.
Neoplasms
Glycophthalocyanines as photosensitizers for triggering mitotic catastrophe and apoptosis in cancer cells.
Neoplasms
Glycyrrhizic acid prevents Ultraviolet- B induced photodamage: A role for mitogen-activated protein kinases, nuclear factor kappa B and mitochondrial apoptotic pathway.
Neoplasms
Gold nanocage assemblies for selective second harmonic generation imaging of cancer cell.
Neoplasms
High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.
Neoplasms
High sensitivity of human epidermal keratinocytes (HaCaT) to topoisomerase inhibitors.
Neoplasms
Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity.
Neoplasms
Histamine differentially regulates the production of Th1 and Th2 chemokines by keratinocytes through histamine H1 receptor.
Neoplasms
Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.
Neoplasms
Human papillomavirus-16 E7 interacts with glutathione S-transferase P1 and enhances its role in cell survival.
Neoplasms
Icariin inhibits inflammation via immunomodulation of the cutaneous hypothalamus-pituitary-adrenal axis in vitro.
Neoplasms
IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors.
Neoplasms
Imaging and detection of cell apoptosis byIn vitrophotodynamic therapy applications of zinc (II) phthalocyanine on human melanoma cancer.
Neoplasms
Imatinib mesylate elicits extracellular signal-related kinase (ERK) activation and enhances the survival of ?-irradiated epithelial cells.
Neoplasms
Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin.
Neoplasms
Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris.
Neoplasms
Immunomodulatory and Anti-inflammatory Effects of Asiatic Acid in a DNCB-Induced Atopic Dermatitis Animal Model.
Neoplasms
Impacts of the SOAT1 genetic variants and protein expression on HBV-related hepatocellular carcinoma.
Neoplasms
Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response.
Neoplasms
In vitro and in vivo downregulation of C3 by lipoteichoic acid isolated from Lactobacillus plantarum K8 suppressed cytokine-mediated complement system activation.
Neoplasms
In Vitro Anti-Inflammatory, Anti-Oxidant, and Cytotoxic Activities of Four Curcuma Species and the Isolation of Compounds from Curcuma aromatica Rhizome.
Neoplasms
In vitro antiproliferative activity of uncommon xanthones from branches of Garcinia achachairu.
Neoplasms
In vivo synthesis of selenium nanoparticles by Halococcus salifodinae BK18 and their anti-proliferative properties against HeLa cell line.
Neoplasms
Increased release of the tumour necrosis factor receptor p75 by immortalized human keratinocytes results from an activated shedding mechanism and is not related to augmented steady-state levels of p75 mRNA.
Neoplasms
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study.
Neoplasms
Inflammatory cytokine tumor necrosis factor-alpha enhances nerve growth factor production in human keratinocytes, HaCaT cells.
Neoplasms
Inhibition of calcium-activated chloride channel ANO1 suppresses proliferation and induces apoptosis of epithelium originated cancer cells.
Neoplasms
Inhibition of cytosolic and mitochondrial creatine kinase by siRNA in HaCaT- and HeLaS3-cells affects cell viability and mitochondrial morphology.
Neoplasms
Inhibition of lipopolysaccharide-induced interleukin-1beta and tumor necrosis factor-alpha production by menthone through nuclear factor-kappaB signaling pathway in HaCat cells.
Neoplasms
Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis.
Neoplasms
Inhibition of tumor necrosis factor-alpha stimulated NFkappaB/p65 in human keratinocytes by alpha-melanocyte stimulating hormone and adrenocorticotropic hormone peptides.
Neoplasms
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.
Neoplasms
Inhibitory effect of strawberry geranium (Saxifraga stolonifera) on Toll-like receptor 2-mediated inflammatory response in human skin keratinocytes.
Neoplasms
Inhibitory effects of heartwood extracts of Broussonetia kazinoki Sieb on the development of atopic dermatitis in NC/Nga mice.
Neoplasms
Inhibitory Effects of Helianthus tuberosus Ethanol Extract on Dermatophagoides farina body-induced Atopic Dermatitis Mouse Model and Human Keratinocytes.
Neoplasms
Innovative bola-surfactant niosomes as topical delivery systems of 5-fluorouracil for the treatment of skin cancer.
Neoplasms
Integration of the activation of the human hyaluronan synthase 2 gene promoter by common cofactors of the transcription factors retinoic acid receptor and nuclear factor kappaB.
Neoplasms
Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells.
Neoplasms
Intracellular mechanisms underlying lipid accumulation (white opaque substance) in gastric epithelial neoplasms: A pilot study of expression profiles of lipid-metabolism-associated genes.
Neoplasms
Investigation of the corticotropin-releasing hormone-proopiomelanocortin axis in various skin tumours.
Neoplasms
Iodinated chlorin p6 copper complex induces anti-proliferative effect in oral cancer cells through elevation of intracellular reactive oxygen species.
Neoplasms
Jasmonic Acid Induces Endoplasmic Reticulum Stress with Different Outcome in Cultured Normal and Tumor Epidermal Cells.
Neoplasms
Keratinocyte proinflammatory responses to adherent and nonadherent group A streptococci.
Neoplasms
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.
Neoplasms
Laminaria japonica Suppresses the Atopic Dermatitis-Like Responses in NC/Nga Mice and Inflamed HaCaT Keratinocytes via the Downregulation of STAT1.
Neoplasms
LC-MS profiling highlights hazelnut (Nocciola di Giffoni PGI) shells as a byproduct rich in antioxidant phenolics.
Neoplasms
Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2.
Neoplasms
Low-concentration vemurafenib induces the proliferation and invasion of human HaCaT keratinocytes through mitogen-activated protein kinase pathway activation.
Neoplasms
Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling.
Neoplasms
Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.
Neoplasms
Matrix metalloproteinase-19 expression in normal and diseased skin: dysregulation by epidermal proliferation.
Neoplasms
Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation.
Neoplasms
Matrix metalloproteinase-21 expression is associated with keratinocyte differentiation and upregulated by retinoic acid in HaCaT cells.
Neoplasms
MCM5 Expression Is Associated With the Grade of Malignancy and Ki-67 Antigen in LSCC.
Neoplasms
Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes.
Neoplasms
Mechanism of thymus- and activation-regulated chemokine (TARC)/CCL17 production and its modulation by roxithromycin.
Neoplasms
Mechanisms by which the N-terminal 24 amino acids of the p55 regulatory subunit of phosphatidylinositol 3-kinase affect endotoxin-induced cytokine release in human keratinocytes.
Neoplasms
Mechanistic investigations of antitumor activity of a Rhodamine B?oleanolic acid derivative bioconjugate.
Neoplasms
Methyl 5-Chloro-4,5-didehydrojasmonate (J7) Inhibits Macrophage-Derived Chemokine Production via Down-Regulation of the Signal Transducers and Activators of Transcription 1 Pathway in HaCaT Human Keratinocytes.
Neoplasms
Modification of gene expression by melatonin in UVB-irradiated HaCaT keratinocyte cell lines using a cDNA microarray.
Neoplasms
Modulation of the IL-1 cytokine network in keratinocytes by intracellular IL-1 alpha and IL-1 receptor antagonist.
Neoplasms
Multi-Omics Analysis to Examine Gene Expression and Metabolites From Multisite Adipose-Derived Mesenchymal Stem Cells.
Neoplasms
Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.
Neoplasms
Myrcia splendens (Sw.) DC. (syn. M. fallax (Rich.) DC.) (Myrtaceae) Essential Oil from Amazonian Ecuador: A Chemical Characterization and Bioactivity Profile.
Neoplasms
Myricetin and naringenin inhibit human squamous cell carcinoma proliferation and migration in vitro.
Neoplasms
Nicotinamide downregulates gene expression of interleukin-6, interleukin-10, monocyte chemoattractant protein-1, and tumour necrosis factor-? gene expression in HaCaT keratinocytes after ultraviolet B irradiation.
Neoplasms
Non-covalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI-1.
Neoplasms
Novel 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives as potent anticancer agents - Synthesis, molecular structure, QSAR studies and metabolic stability.
Neoplasms
Novel 2-benzylthio-5-(1,3,4-oxadiazol-2-yl)benzenesulfonamides with anticancer activity: Synthesis, QSAR study, and metabolic stability.
Neoplasms
Novel Processed Form of Syndecan-1 Shed from SCC-9 Cells Plays a Role in Cell Migration.
Neoplasms
Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro.
Neoplasms
Oxymatrine Sensitizes the HaCaT Cells to the IFN-? Pathway and Downregulates MDC, ICAM-1, and SOCS1 by Activating p38, JNK, and Akt.
Neoplasms
PAF-receptor in inflammatory versus non inflammatory human epidermis, cell cultures and embryonal cells.
Neoplasms
Palmitic Acid Induces Production of Proinflammatory Cytokines Interleukin-6, Interleukin-1?, and Tumor Necrosis Factor-? via a NF-?B-Dependent Mechanism in HaCaT Keratinocytes.
Neoplasms
Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.
Neoplasms
Pannexin-3 Deficiency Delays Skin Wound Healing in Mice due to Defects in Channel Functionality.
Neoplasms
Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity.
Neoplasms
Pharmacological importance, characterization and applications of gold and silver nanoparticles synthesized by Panax ginseng fresh leaves.
Neoplasms
Photodynamic therapy of tumour cells mediated by the natural anthraquinone parietin and blue light.
Neoplasms
Physical Plasma-Treated Skin Cancer Cells Amplify Tumor Cytotoxicity of Human Natural Killer (NK) Cells.
Neoplasms
Physiological status of silver carp (Hypophthalmichthys molitrix) in the Illinois River: An assessment of fish at the leading edge of the invasion front.
Neoplasms
Plasminogen activator inhibitor-2: a molecular biomarker for head and neck cancer progression.
Neoplasms
Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas.
Neoplasms
Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells.
Neoplasms
Pleiotropic effects of human papillomavirus type 16 E6 oncogene expression in human epithelial cell lines.
Neoplasms
Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism.
Neoplasms
Potentiation of Kras peptide cancer vaccine by avasimibe, a cholesterol modulator.
Neoplasms
Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor ? Superfamily Type 1 Receptors.
Neoplasms
Prognostic significance of two lipid metabolism enzymes, HADHA and ACAT2, in clear cell renal cell carcinoma.
Neoplasms
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Neoplasms
Protective effect of Codium fragile against UVB-induced pro-inflammatory and oxidative damages in HaCaT cells and BALB/c mice.
Neoplasms
Protective Effect of Inositol Hexaphosphate Against UVB Damage in HaCaT Cells and Skin Carcinogenesis in SKH1 Hairless Mice.
Neoplasms
Protective Effect of Processed Panax ginseng, Sun Ginseng on UVB-irradiated Human Skin Keratinocyte and Human Dermal Fibroblast.
Neoplasms
Protective role of copper, zinc superoxide dismutase against UVB-induced injury of the human keratinocyte cell line HaCaT.
Neoplasms
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma.
Neoplasms
Purification of a polysaccharide from Gynostemma pentaphyllum Makino and its therapeutic advantages for psoriasis
Neoplasms
Purification of a polysaccharide from Gynostemma pentaphyllum Makino and its therapeutic advantages for psoriasis.
Neoplasms
Pyropia yezoensis Extract Suppresses IFN-Gamma- and TNF-Alpha-Induced Proinflammatory Chemokine Production in HaCaT Cells via the Down-Regulation of NF-?B.
Neoplasms
Pyrus ussuriensis Maxim. leaves extract ameliorates DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice.
Neoplasms
Quantitative analysis and anti-inflammatory effects of Gleditsia sinensis thorns in RAW 264.7 macrophages and HaCaT keratinocytes.
Neoplasms
Radiolabeling and in vitro evaluation of a new 5-Fluorouracil derivative with cell culture studies.
Neoplasms
Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
Neoplasms
Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing.
Neoplasms
Rhodiola crenulata Attenuates ?-Ray Induced Cellular Injury via Modulation of Oxidative Stress in Human Skin Cells.
Neoplasms
Role of iron in tumor cell protection from the pro-apoptotic effect of nitric oxide.
Neoplasms
Rosa davurica Pall. improves DNCB-induced atopic dermatitis in mice and regulated TNF-Alpa/IFN-gamma-induced skin inflammatory responses in HaCaT cells.
Neoplasms
Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity.
Neoplasms
Sargahydroquinoic acid inhibits TNF?-induced AP-1 and NF-?B signaling in HaCaT cells through PPAR? activation.
Neoplasms
Sargassum fulvellum Protects HaCaT Cells and BALB/c Mice from UVB-Induced Proinflammatory Responses.
Neoplasms
Saussurea lappa alleviates inflammatory chemokine production in HaCaT cells and house dust mite-induced atopic-like dermatitis in Nc/Nga mice.
Neoplasms
SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes.
Neoplasms
Self-assembled nanostructures of phosphomolybdate, nucleobase and metal ions synthesis and their in vitro cytotoxicity studies on cancer cell lines.
Neoplasms
Sera/Organ Lysates of Selected Animals Living in Polluted Environments Exhibit Cytotoxicity against Cancer Cell Lines.
Neoplasms
Shikonin inhibits CEBPD downregulation in IL?17?treated HaCaT cells and in an imiquimod?induced psoriasis model.
Neoplasms
Signaling through cholesterol esterification: a new pathway for the cholecystokinin 2 receptor involved in cell growth and invasion.
Neoplasms
SiO2-PVA-Fe(acac)3 Hybrid Based Superparamagnetic Nanocomposites for Nanomedicine: Morpho-textural Evaluation and In Vitro Cytotoxicity Assay.
Neoplasms
Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
Neoplasms
Spilanthol inhibits TNF???induced ICAM?1 expression and pro?inflammatory responses by inducing heme oxygenase?1 expression and suppressing pJNK in HaCaT keratinocytes.
Neoplasms
Stabilization of FASN by ACAT1-mediated GNPAT acetylation promotes lipid metabolism and hepatocarcinogenesis.
Neoplasms
Stable over-expression of PPAR?/? and PPAR? to examine receptor signaling in human HaCaT keratinocytes.
Neoplasms
Stratification of patients with clear cell renal cell carcinoma to facilitate drug repositioning.
Neoplasms
Sulforaphane suppresses TARC/CCL17 and MDC/CCL22 expression through heme oxygenase-1 and NF-?B in human keratinocytes.
Neoplasms
Surface-Modified Industrial Acrylonitrile Butadiene Styrene 3D Scaffold Fabrication by Gold Nanoparticle for Drug Screening.
Neoplasms
Sustained nontumorigenic phenotype correlates with a largely stable chromosome content during long-term culture of the human keratinocyte line HaCaT.
Neoplasms
Synergistic Inhibition of Tumor Necrosis Factor-Alpha-Stimulated Pro-Inflammatory Cytokine Expression in HaCaT Cells by a Combination of Rapamycin and Mycophenolic Acid.
Neoplasms
Synergy of Dendritic Cell Vaccines and Avasimibe in Treatment of Head and Neck Cancer in Mice.
Neoplasms
Synthesis of (Z)-1-(1,3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents.
Neoplasms
Synthesis of fluorescent molybdenum nanoclusters at ambient temperature and their application in biological imaging.
Neoplasms
Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors.
Neoplasms
Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard's T and P reagents.
Neoplasms
Telmisartan Influences the Antiproliferative Activity of Linoleic Acid in Human Colon Cancer Cells.
Neoplasms
Testing Lab-on-a-Chip Technology for Culturing Human Melanoma Cells under Simulated Microgravity.
Neoplasms
Tetrahedral framework nucleic acids promote scarless healing of cutaneous wounds via the AKT-signaling pathway.
Neoplasms
Tetrandrine inhibits the proliferation and cytokine production induced by IL-22 in HaCaT cells.
Neoplasms
TGF-beta1 + EGF-initiated invasive potential in transformed human keratinocytes is coupled to a plasmin/MMP-10/MMP-1-dependent collagen remodeling axis: role for PAI-1.
Neoplasms
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-?B.
Neoplasms
The crucial role of IL-22 and its receptor on TARC production and T cell migration by HDM extract.
Neoplasms
The Effects of Costaria costata Extracts on Atopic Dermatitis in an In Vitro Model.
Neoplasms
The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT).
Neoplasms
The Expressions of TGF-?(1) and IL-10 in Cultured Fibroblasts after ALA-IPL Photodynamic Treatment.
Neoplasms
The Extract of D. dasycarpus Ameliorates Oxazolone-Induced Skin Damage in Mice by Anti-Inflammatory and Antioxidant Mechanisms.
Neoplasms
The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation.
Neoplasms
The platelet-activating factor receptor protects epidermal cells from tumor necrosis factor (TNF) alpha and TNF-related apoptosis-inducing ligand-induced apoptosis through an NF-kappa B-dependent process.
Neoplasms
The prevention of TNF-?/IFN-? mixture-induced inflammation in human keratinocyte and atopic dermatitis-like skin lesions in Nc/Nga mice by mineral-balanced deep sea water.
Neoplasms
The proapoptotic tumor suppressor protein kinase C-delta is lost in human squamous cell carcinomas.
Neoplasms
The recent insights into the function of ACAT1: A possible anti-cancer therapeutic target.
Neoplasms
The relative abundance of oxygen alkyl-related groups in aliphatic domains is involved in the main pharmacological-pleiotropic effects of humic acids.
Neoplasms
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties.
Neoplasms
The space of enzyme regulation in HeLa cells can be inferred from its intracellular metabolome.
Neoplasms
The vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation.
Neoplasms
Therapeutic Effect of Rumex japonicus Houtt. on DNCB-Induced Atopic Dermatitis-Like Skin Lesions in Balb/c Mice and Human Keratinocyte HaCaT Cells.
Neoplasms
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.
Neoplasms
TNIP1 reduction sensitizes keratinocytes to post-receptor signalling following exposure to TLR agonists.
Neoplasms
Tonggyu-tang, a traditional Korean medicine, suppresses pro-inflammatory cytokine production through inhibition of MAPK and NF-?B activation in human mast cells and keratinocytes.
Neoplasms
Traditional Aboriginal Preparation Alters the Chemical Profile of Carica papaya Leaves and Impacts on Cytotoxicity towards Human Squamous Cell Carcinoma.
Neoplasms
Traditional Herbal Formula Banhasasim-tang Exerts Anti-Inflammatory Effects in RAW 264.7 Macrophages and HaCaT Keratinocytes.
Neoplasms
Traditional herbal formula Jakyakgamcho-tang (Paeonia lactiflora and Glycyrrhiza uralensis) impairs inflammatory chemokine production by inhibiting activation of STAT1 and NF-?B in HaCaT cells.
Neoplasms
Trehalose, sucrose and raffinose are novel activators of autophagy in human keratinocytes through an mTOR-independent pathway.
Neoplasms
Trifloxystrobin induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in HaCaT, human keratinocyte cells.
Neoplasms
Tumor-specific gene expression using regulatory elements of the glucose transporter isoform 1 gene.
Neoplasms
Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells.
Neoplasms
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature.
Neoplasms
Two new hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and cytotoxic activity of aggregatin D.
Neoplasms
Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex.
Neoplasms
Ultraviolet B irradiation-induced G2 cell cycle arrest in human keratinocytes by inhibitory phosphorylation of the cdc2 cell cycle kinase.
Neoplasms
Ultraviolet-A-induced transactivation of the vascular endothelial growth factor gene in HaCaT keratinocytes is conveyed by activator protein-2 transcription factor.
Neoplasms
Umbelliferone reduces the expression of inflammatory chemokines in HaCaT cells and DNCB/DFE-induced atopic dermatitis symptoms in mice.
Neoplasms
UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin.
Neoplasms
UVA-induced epigenetic regulation of P16(INK4a) in human epidermal keratinocytes and skin tumor derived cells.
Neoplasms
UVB-induced interleukin-18 production is downregulated by tannic acids in human HaCaT keratinocytes.
Neoplasms
Vascular Endothelial Growth Factor Induced Skin Carcinogenesis depends on Recruitment and Alternative Activation of Macrophages.
Neoplasms
Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line.
Neoplasms
Vitamin D inhibits the activation of stress-activated protein kinases by physiological and environmental stresses in keratinocytes.
Neoplasms
Water Extract of Rubus coreanus Prevents Inflammatory Skin Diseases In Vitro Models.
Neoplasms
Well Defined Poly(Methyl Methacrylate)-Fe3O4/Poly(Vinyl Pivalate) Core-Shell Superparamagnetic Nanoparticles: Design and Evaluation of In Vitro Cytotoxicity Activity Against Cancer Cells.
Neoplasms
Xanthii fructus extract inhibits TNF-?/IFN-?-induced Th2-chemokines production via blockade of NF-?B, STAT1 and p38-MAPK activation in human epidermal keratinocytes.
Neoplasms
Zinc oxide nanoparticles synthesized from Allium cepa prevents UVB radiation mediated inflammation in human epidermal keratinocytes (HaCaT cells).
Nephritis, Hereditary
Sterol-O-acyltransferase-1 has a role in kidney disease associated with diabetes and Alport Syndrome.
Nephrotic Syndrome
Acyl-Coenzyme A: Cholesterol Acyltransferase-1 is Related to Hyperlipidemia in Children with Nephrotic Syndrome.
Nephrotic Syndrome
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Nephrotic Syndrome
Up-regulation of acyl-coenzyme A:cholesterol acyltransferase (ACAT) in nephrotic syndrome.
Neural Tube Defects
The association and significance of H3K27me3 and a folate metabolic gene ACat2 in neural tube defects.
Neuralgia
Thymus algeriensis and Thymus fontanesii exert neuroprotective effect against chronic constriction injury-induced neuropathic pain in rats.
Neuroblastoma
A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities.
Neuroblastoma
ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-?-processing alteration.
Neuroblastoma
NBPF7 promotes the proliferation of ?-catenin-knockdown HaCaT cells via functional interaction with the NF-?B pathway.
Neuroblastoma
Silencing the ACAT1 Gene in Human SH-SY5Y Neuroblastoma Cells Inhibits the Expression of Cyclo-Oxygenase 2 (COX2) and Reduces ?-Amyloid-Induced Toxicity Due to Activation of Protein Kinase C (PKC) and ERK.
Neuroblastoma
Synthesis of Bioactive Chlorogenic Acid-Silica Hybrid Materials via the Sol-Gel Route and Evaluation of Their Biocompatibility.
Neuroblastoma
Transcription of human neuronal nitric oxide synthase mRNAs derived from different first exons is partly controlled by exon 1-specific promoter sequences.
Neurodegenerative Diseases
Increased expression of acyl-coenzyme A: cholesterol acyltransferase-1 and elevated cholesteryl esters in the hippocampus after excitotoxic injury.
Neurodegenerative Diseases
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases A?1-42 clearance.
Non-alcoholic Fatty Liver Disease
Impact of cholesterol metabolism and the LXRalpha-SREBP-1c pathway on nonalcoholic fatty liver disease.
Non-alcoholic Fatty Liver Disease
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
Non-alcoholic Fatty Liver Disease
Protein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease.
Non-alcoholic Fatty Liver Disease
[Effect of leech on lipid metabolism and liver in hyperlipidemia rats].
Obesity
Extracting time-dependent obese-diabetic specific networks in hepatic proteome analysis.
Obesity
Leptin promotes the migration and invasion of breast cancer cells by upregulating ACAT2.
Obesity
Myeloid-specific Acat1 ablation attenuates inflammatory responses in macrophages, improves insulin sensitivity, and suppresses diet-induced obesity.
Obesity
Pharmacological inhibition of acyl-coenzyme A:cholesterol acyltransferase alleviates obesity and insulin resistance in diet-induced obese mice by regulating food intake.
Obesity
Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms.
Osteosarcoma
Determination of Immediate vs. Kinetic Growth Retardation in Physically Plasma-treated Cells by Experimental and Modelling Data.
Ovarian Neoplasms
Assessment of acyl-CoA cholesterol acyltransferase (ACAT-1) role in ovarian cancer progression-An in vitro study.
Ovarian Neoplasms
Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.
Ovarian Neoplasms
Photodynamic therapy of tumour cells mediated by the natural anthraquinone parietin and blue light.
Ovarian Neoplasms
Transplatin is cytotoxic when photoactivated: enhanced formation of DNA cross-links.
Pancreatic Neoplasms
Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer.
Pancreatic Neoplasms
Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana.
Papilloma
Dehydrocostus lactone suppresses cell growth and induces apoptosis in recombinant human papilloma virus?18 HaCaT cells via the PI3K/Akt signaling pathway.
Papillomavirus Infections
DNAJA4 deficiency enhances NF-kappa B-related growth arrest induced by hyperthermia in human keratinocytes.
Papillomavirus Infections
Human Keratinocyte Cultures in the Investigation of Early Steps of Human Papillomavirus Infection.
Papillomavirus Infections
Identification of TRAPPC8 as a host factor required for human papillomavirus cell entry.
Papillomavirus Infections
Integrative analyses reveal novel strategies in HPV11,-16 and -45 early infection.
Papillomavirus Infections
The cytotoxic mechanism of epigallocatechin gallate on proliferative HaCaT keratinocytes.
Pemphigoid, Bullous
Decreased expression levels of complement regulator CD55 contribute to the development of bullous pemphigoid.
Pemphigus
Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris.
phosphatidylcholine-sterol o-acyltransferase deficiency
Demonstration of intact intracellular cholesterol esterification and normal low-density lipoprotein pathway in fibroblasts from a patient with lecithin:cholesterol acyltransferase deficiency.
phosphatidylcholine-sterol o-acyltransferase deficiency
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Photosensitivity Disorders
A comparative study on the enhancement efficacy of specific and non-specific iron chelators for protoporphyrin IX production and photosensitization in HaCat cells.
Photosensitivity Disorders
Rapid induction of apoptosis in human keratinocytes with the photosensitizer QLT0074 via a direct mitochondrial action.
Porcine Reproductive and Respiratory Syndrome
Exposure to heat-inactivated Trichophyton rubrum resulting in a limited immune response of human keratinocytes.
Pressure Ulcer
Anti-antioxidant impacts of circZNF609 silence in HaCaT cells through regulating miR-145.
Pressure Ulcer
Therapeutic Effect of External Application of Ligustrazine Combined with Holistic Nursing on Pressure Sores.
Prostatic Neoplasms
Bioconjugated graphene oxide-based Raman probe for selective identification of SKBR3 breast cancer cells.
Prostatic Neoplasms
Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression.
Prostatic Neoplasms
Identification of Genes Required for Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cells In Vitro.
Prostatic Neoplasms
Knockdown of sterol O-acyltransferase 1 (SOAT1) suppresses SCD1-mediated lipogenesis and cancer procession in prostate cancer.
Prostatic Neoplasms
Positive regulation of prostate cancer cell growth by lipid droplet forming and processing enzymes DGAT1 and ABHD5.
Prostatic Neoplasms
Quantitative Proteomics Reveals that Enzymes of the Ketogenic Pathway are Associated with Prostate Cancer Progression.
Prostatic Neoplasms
Sirtuin 5 regulates the proliferation, invasion and migration of prostate cancer cells through acetyl-CoA acetyltransferase 1.
Prostatic Neoplasms
Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways.
Proteinuria
Acyl-coenzyme A:cholesterol acyltransferase inhibition ameliorates proteinuria, hyperlipidemia, lecithin-cholesterol acyltransferase, SRB-1, and low-denisty lipoprotein receptor deficiencies in nephrotic syndrome.
Proteinuria
Sterol Regulatory Element-Binding Proteins, Liver X Receptor, ABCA1 Transporter, CD36, Scavenger Receptors A1 and B1 in Nephrotic Kidney.
Psoriasis
A Preliminary Study of the Effect of Semaphorin 3A and Acitretin on the Proliferation, Migration, and Apoptosis of HaCaT Cells.
Psoriasis
A Randomized, Double-Blind, Controlled Clinical Study on the Curative Effect of Huaier on Mild-to-Moderate Psoriasis and an Experimental Study on the Proliferation of Hacat Cells.
Psoriasis
Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7.
Psoriasis
Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling.
Psoriasis
All-trans-retinoic acid and 13-cis-retinoic acid: pharmacokinetics and biological activity in different cell culture models of human keratinocytes.
Psoriasis
Altered expression of prohibitin in psoriatic lesions and its cellular implication.
Psoriasis
Amentoflavone protects against psoriasis-like skin lesion through suppression of NF-?B-mediated inflammation and keratinocyte proliferation.
Psoriasis
Antiproliferation of keratinocytes and alleviation of psoriasis by the ethanol extract of Artemisia capillaris.
Psoriasis
Ar-Turmerone Exerts Anti-proliferative and Anti-inflammatory Activities in HaCaT Keratinocytes by Inactivating Hedgehog Pathway.
Psoriasis
Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor ? (TNF-?) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-?B) Signaling Pathway.
Psoriasis
Calcipotriol inhibits proliferation of human keratinocytes by downregulating STAT1 and STAT3 signaling.
Psoriasis
Circ_0061012 contributes to IL-22-induced proliferation, migration and invasion in keratinocytes through miR-194-5p/GAB1 axis in psoriasis.
Psoriasis
Co-localization of COX-2, CYP4F8, and mPGES-1 in epidermis with prominent expression of CYP4F8 mRNA in psoriatic lesions.
Psoriasis
Combination of retinoids and narrow-band ultraviolet B inhibits matrix metalloproteinase 13 expression in HaCaT keratinocytes and a mouse model of psoriasis.
Psoriasis
Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells.
Psoriasis
Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Psoriasis
Correction: Boche?ska, K. et al. Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis. Int. J. Mol. Sci. 2019, 20, 2255.
Psoriasis
Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-?B/AP-1 activation.
Psoriasis
Dermal Mesenchymal Stem Cells from Psoriatic Lesions Stimulate HaCaT Cell Proliferation, Differentiation, and Migration via Activating the PI3K/AKT Signaling Pathway.
Psoriasis
Differential expression of D-type cyclins in HaCaT keratinocytes and in psoriasis.
Psoriasis
Dithranol upregulates IL-10 receptors on the cultured human keratinocyte cell line HaCaT.
Psoriasis
DUSP1/MKP-1 regulates proliferation and apoptosis in keratinocytes through the ERK/Elk-1/Egr-1 signaling pathway.
Psoriasis
E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.
Psoriasis
Effects of aloe polysaccharide, a polysaccharide extracted from Aloe vera, on TNF???induced HaCaT cell proliferation and the underlying mechanism in psoriasis.
Psoriasis
Enhanced Antipsoriatic Activity of Mycophenolic Acid Against the TNF-?-Induced HaCaT Cell Proliferation by Conjugated Poloxamer Micelles.
Psoriasis
Ethanol and acetone stimulate the proliferation of HaCaT keratinocytes: the possible role of alcohol in exacerbating psoriasis.
Psoriasis
Evaluation of the anti-proliferative properties of selected psoriasis-treating Chinese medicines on cultured HaCaT cells.
Psoriasis
Exploring the mode of action of dithranol therapy for psoriasis: a metabolomic analysis using HaCaT cells.
Psoriasis
Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases.
Psoriasis
EZH2 is involved in psoriasis progression by impairing miR-125a-5p inhibition of SFMBT1 and leading to inhibition of the TGF?/SMAD pathway.
Psoriasis
F(2)-isoprostanes: sensitive biomarkers of oxidative stress in vitro and in vivo: a gas chromatography-mass spectrometric approach.
Psoriasis
FGF-7 facilitates the process of psoriasis by inducing TNF-? expression in HaCaT cells.
Psoriasis
Fluorescent Imaging for Assessment of the Effect of Combined Application of Electroporation and Rifampicin on HaCaT Cells as a New Therapeutic Approach for Psoriasis.
Psoriasis
FOS-like antigen 1 is highly expressed in human psoriasis tissues and promotes the growth of HaCaT cells in vitro.
Psoriasis
FOXM1 regulates the proliferation, apoptosis and inflammatory response of keratinocytes through the NF-?B signaling pathway.
Psoriasis
Fuzhenghefuzhiyang Formula (FZHFZY) Improves Epidermal Differentiation via Suppression of the Akt/mTORC1/S6K1 Signalling Pathway in Psoriatic Models.
Psoriasis
Gardiquimod inhibits the expression of calcium-induced differentiation markers in HaCaT cells.
Psoriasis
Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis.
Psoriasis
Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract.
Psoriasis
HIF-1? may promote glycolysis in psoriasis vulgaris via upregulation of CD147 and GLUT1.
Psoriasis
hsa-miR-4516 Mediated Downregulation of STAT3/CDK6/UBE2N Plays a Role in PUVA Induced Apoptosis in Keratinocytes.
Psoriasis
Hyperforin Ameliorates Imiquimod-Induced Psoriasis-Like Murine Skin Inflammation by Modulating IL-17A-Producing ?? T Cells.
Psoriasis
Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.
Psoriasis
IL-33 is secreted by psoriatic keratinocytes and induces pro-inflammatory cytokines via keratinocyte and mast cell activation.
Psoriasis
Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin.
Psoriasis
Inhibiting Interleukin-18 Production Through the Mitogen-Activated Protein Kinase Pathway, A Potential Role of Corticotropin-Releasing Hormone in Chronic Plaque Psoriasis.
Psoriasis
Isoliquiritigenin prevents the progression of psoriasis-like symptoms by inhibiting NF-?B and proinflammatory cytokines.
Psoriasis
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Psoriasis
LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8.
Psoriasis
Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis.
Psoriasis
MicroRNA-125a Correlates with Decreased Psoriasis Severity and Inflammation and Represses Keratinocyte Proliferation.
Psoriasis
MicroRNA-215-5p inhibits the proliferation of keratinocytes and alleviates psoriasis-like inflammation by negatively regulating DYRK1A and its downstream signalling pathways.
Psoriasis
MicroRNA-520a suppresses the proliferation and mitosis of HaCaT cells by inactivating protein kinase B.
Psoriasis
MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris.
Psoriasis
MiR-155 promotes cell proliferation and inhibits apoptosis by PTEN signaling pathway in the psoriasis.
Psoriasis
miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1.
Psoriasis
MiR-20a-3p regulates TGF-?1/Survivin pathway to affect keratinocytes proliferation and apoptosis by targeting SFMBT1 in vitro.
Psoriasis
MiR-221-3p as a Potential Biomarker for Patients with Psoriasis and Its Role in Inflammatory Responses in Keratinocytes.
Psoriasis
MiR-330 inhibits IL-22-induced keratinocyte proliferation through targeting CTNNB1.
Psoriasis
MiR-99a inhibits keratinocyte proliferation by targeting Frizzled-5 (FZD5) / FZD8 through ?-catenin signaling in psoriasis.
Psoriasis
miR124-3p/FGFR2 axis inhibits human keratinocyte proliferation and migration and improve the inflammatory microenvironment in psoriasis.
Psoriasis
Neutrophil elastase promotes proliferation of HaCaT cell line and transwell psoriasis organ culture model.
Psoriasis
Nitidine chloride induces S phase cell cycle arrest and mitochondria-dependent apoptosis in HaCaT cells and ameliorates skin lesions in psoriasis-like mouse models.
Psoriasis
Paeoniflorin inhibits proliferation and migration of psoriatic keratinocytes via the lncRNA NEAT1/miR-3194-5p/Galectin-7 axis.
Psoriasis
PGRN Suppresses Inflammation and Promotes Autophagy in Keratinocytes Through the Wnt/?-Catenin Signaling Pathway.
Psoriasis
Pro-oxidant status and Nrf2 levels in psoriasis vulgaris skin tissues and dimethyl fumarate-treated HaCaT cells.
Psoriasis
Proinflammatory cytokine production in HaCaT cells treated by eosin: implications for the topical treatment of psoriasis.
Psoriasis
PSORI-CM02 ameliorates psoriasis in vivo and in vitro by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway.
Psoriasis
PSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice.
Psoriasis
Purification of a polysaccharide from Gynostemma pentaphyllum Makino and its therapeutic advantages for psoriasis
Psoriasis
Purification of a polysaccharide from Gynostemma pentaphyllum Makino and its therapeutic advantages for psoriasis.
Psoriasis
Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes.
Psoriasis
Rapamycin ameliorates psoriasis by regulating the expression and methylation levels of tropomyosin via ERK1/2 and mTOR pathways in vitro and in vivo.
Psoriasis
Realgar-mediated growth inhibition on HaCaT human keratinocytes is associated with induction of apoptosis.
Psoriasis
Research Note Mesenchymal stem cells from skin lesions of psoriasis patients promote proliferation and inhibit apoptosis of HaCaT cells.
Psoriasis
RNA-seq reveal RNA binding protein GNL3 as a key mediator in the development of psoriasis vulgaris by regulating the IL23/IL17 axis.
Psoriasis
Rosmarinic acid protects mice from imiquimod induced psoriasis-like skin lesions by inhibiting the IL-23/Th17 axis via regulating Jak2/Stat3 signaling pathway.
Psoriasis
Shikonin inhibits CEBPD downregulation in IL?17?treated HaCaT cells and in an imiquimod?induced psoriasis model.
Psoriasis
Silencing of miR?155 suppresses inflammatory responses in psoriasis through inflammasome NLRP3 regulation.
Psoriasis
Sortilin regulates keratinocyte proliferation and apoptosis through the PI3K-AKT signaling pathway.
Psoriasis
Taxifolin attenuates IMQ-induced murine psoriasis-like dermatitis by regulating T helper cell responses via Notch1 and JAK2/STAT3 signal pathways.
Psoriasis
The alpha-defensins HNP-1 and HNP-2 are dominant self-peptides presented by HLA class-II molecules in lesional psoriatic skin.
Psoriasis
The potential of Diosgenin in treating psoriasis: Studies from HaCaT keratinocytes and imiquimod-induced murine model.
Psoriasis
Topical Sunitinib ointment alleviates Psoriasis-like inflammation by inhibiting the proliferation and apoptosis of keratinocytes.
Psoriasis
TRB3 is elevated in psoriasis vulgaris lesions and mediates HaCaT cells proliferation in vitro.
Psoriasis
Triptolide Inhibits the Proliferation of HaCaT Cells Induced by IL22 via Upregulating miR-181b-5p.
Psoriasis
[Effect of shikonin on proliferation of keratinocytes induced by interleukin-17 and expression of chemokines].
Psoriasis
[Genetically predetermined limitation in the use of HaCaT cells that affects their ability to serve as an experimental model of psoriasis].
Psoriasis
[Mechanism about therapeutic effect of meisoindigo on psoriasis via down-regulation of the TLR4-TAK-NF-kappaB pathways].
Psoriasis
[Molecular Mechanism of KLF4 Up-regulating Keratin 17 Expression in Keratinocytes].
Pyoderma Gangrenosum
Gene Therapy for Pyoderma Gangrenosum: Optimal Transfection Conditions and Effect of Drugs on Gene Delivery in the HaCaT Cell Line Using Cationic Liposomes.
Renal Insufficiency
Atorvastatin Improves Hepatic Lipid Metabolism and Protects Renal Damage in Adenine-Induced Chronic Kidney Disease in Sprague-Dawley Rats.
Retinoblastoma
Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression.
Retinoblastoma
Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction.
Retinoblastoma
Role of p12(CDK2-AP1) in transforming growth factor-beta1-mediated growth suppression.
Retinoblastoma
ZD1839 induces p15INK4b and causes G1 arrest by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway.
Rosacea
Increased expression of IL-33 in rosacea skin and UVB-irradiated and LL-37-treated HaCaT cells.
Rosacea
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea.
Rosacea
The therapeutic effect of artesunate on rosacea through the inhibition of the JAK/STAT signaling pathway.
Rosacea
Tranexamic acid ameliorates rosacea symptoms through regulating immune response and angiogenesis.
Seizures
Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus.
Seizures
F(2)-isoprostanes: sensitive biomarkers of oxidative stress in vitro and in vivo: a gas chromatography-mass spectrometric approach.
Seizures
Neurobehavioral Deficits in a Rat Model of Recurrent Neonatal Seizures Are Prevented by a Ketogenic Diet and Correlate with Hippocampal Zinc/Lipid Transporter Signals.
Sepsis
Phenotypic and genotypic characteristics of Candida albicans isolates from bloodstream and mucosal infections.
Shock, Septic
Staphylococcal toxins and protein A differentially induce cytotoxicity and release of tumor necrosis factor-alpha from human keratinocytes.
Skin Diseases
Down-regulation of IL-6, IL-8, TNF-? and IL-1? by glucosamine in HaCaT cells, but not in the presence of TNF-?
Skin Diseases
Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis-like skin lesions and TNF-?/IFN-?-induced chemokines production in HaCaT cells.
Skin Diseases
Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases.
Skin Diseases
PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-?B and production of inflammatory cytokines.
Skin Neoplasms
Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis.
Skin Neoplasms
Arsenite Regulates Prolongation of Glycan Residues of Membrane Glycoprotein: A Pivotal Study via Wax Physisorption Kinetics and FTIR Imaging.
Skin Neoplasms
Caffeic acid directly targets ERK1/2 to attenuate solar UV-induced skin carcinogenesis.
Skin Neoplasms
Cell cycle progression data on human skin cancer cells with anticancer synthetic peptide LTX-315 treatment.
Skin Neoplasms
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
Skin Neoplasms
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Skin Neoplasms
Effect of Shenqin biochemical extract on hypoxia-inducible factor-1? expression in ultraviolet B-irradiated HaCaT cells.
Skin Neoplasms
Erratum to: Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.
Skin Neoplasms
Ese-3 Inhibits the Proliferation, Migration, and Invasion of HaCaT Cells by Downregulating PSIP1 and NUCKS1.
Skin Neoplasms
Identification of novel ?Np63?-regulated miRNAs using an optimized small RNA-Seq analysis pipeline.
Skin Neoplasms
Innovative bola-surfactant niosomes as topical delivery systems of 5-fluorouracil for the treatment of skin cancer.
Skin Neoplasms
Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity.
Skin Neoplasms
Physical Plasma-Treated Skin Cancer Cells Amplify Tumor Cytotoxicity of Human Natural Killer (NK) Cells.
Skin Neoplasms
Proteomic analysis and the antimetastatic effect of N-(4-methyl)phenyl-O-(4-methoxy) phenyl-thionocarbamate-induced apoptosis in human melanoma SK-MEL-28 cells.
Skin Neoplasms
Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor.
Skin Neoplasms
Subcellular Raman Microspectroscopy Imaging of Nucleic Acids and Tryptophan for Distinction of Normal Human Skin Cells and Tumorigenic Keratinocytes.
Skin Neoplasms
TGF-beta1 causes epithelial-mesenchymal transition in HaCaT derivatives, but induces expression of COX-2 and migration only in benign, not in malignant keratinocytes.
Skin Neoplasms
The enhanced IL-18 production by UVB irradiation requires ROI and AP-1 signaling in human keratinocyte cell line (HaCaT).
Skin Neoplasms
The Flavonol Isoquercitrin Promotes Mitochondrial-Dependent Apoptosis in SK-Mel-2 Melanoma Cell via the PI3K/AKT/mTOR Pathway.
Skin Neoplasms
Three-Dimensional In Vitro Skin and Skin Cancer Models Based on Human Fibroblast-Derived Matrix.
Skin Neoplasms
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.
Squamous Cell Carcinoma of Head and Neck
Chemical Characterization and in Vitro Cytotoxicity on Squamous Cell Carcinoma Cells of Carica Papaya Leaf Extracts.
Squamous Cell Carcinoma of Head and Neck
Copy number gain and oncogenic activity of YWHAZ/14-3-3zeta in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
E-cigarette vapour is not inert and exposure can lead to cell damage.
Squamous Cell Carcinoma of Head and Neck
Gold nanoparticles conjugated with programmed death-ligand 1 antibodies induce apoptosis of SCC-25 oral squamous cell carcinoma cells via programmed death-ligand 1/signal transducer and transcription 3 pathway.
Squamous Cell Carcinoma of Head and Neck
Model examinatio-n of chemoprevention with retinoids in squamous cell carcinomas of the head and neck region and suitable biomarkers for chemoprevention.
Squamous Cell Carcinoma of Head and Neck
Myricetin and naringenin inhibit human squamous cell carcinoma proliferation and migration in vitro.
Squamous Cell Carcinoma of Head and Neck
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
Squamous Cell Carcinoma of Head and Neck
Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity.
Squamous Cell Carcinoma of Head and Neck
Silencing novel long non-coding RNA FKBP9P1 represses malignant progression and inhibits PI3K/AKT signaling of head and neck squamous cell carcinoma in vitro.
Squamous Cell Carcinoma of Head and Neck
Small Extracellular Vesicles from Head and Neck Squamous Cell Carcinoma Cells Carry a Proteomic Signature for Tumor Hypoxia.
Squamous Cell Carcinoma of Head and Neck
Synergy of Dendritic Cell Vaccines and Avasimibe in Treatment of Head and Neck Cancer in Mice.
Squamous Cell Carcinoma of Head and Neck
The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation.
Squamous Cell Carcinoma of Head and Neck
The Selection of NF?B Inhibitors to Block Inflammation and Induce Sensitisation to FasL-Induced Apoptosis in HNSCC Cell Lines Is Critical for Their Use as a Prospective Cancer Therapy.
Staphylococcal Infections
Biphasic influence of Staphylococcus aureus on human epidermal tight junctions.
Staphylococcal Infections
The Short Lipopeptides (C10)2-KKKK-NH2 and (C12)2-KKKK-NH2 Protect HaCaT Keratinocytes from Bacterial Damage Caused by Staphylococcus aureus Infection in a Co-Culture Model.
Staphylococcal Infections
Water-based extracts of Zizania latifolia inhibit Staphylococcus aureus infection through the induction of human beta-defensin 2 expression in HaCaT cells.
Starvation
Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells.
Starvation
Differential expression of classical nuclear transport factors during cellular proliferation and differentiation.
Starvation
Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A.
Starvation
Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.
Starvation
Monomeric C-mannosyl tryptophan is a degradation product of autophagy in cultured cells.
Starvation
Serum Starvation Sensitizes Anticancer Effect of Anemarrhena asphodeloides via p38/JNK-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells.
sterol o-acyltransferase deficiency
ACAT1 deficiency disrupts cholesterol efflux and alters cellular morphology in macrophages.
sterol o-acyltransferase deficiency
ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages.
sterol o-acyltransferase deficiency
ACAT2 contributes cholesteryl esters to newly secreted VLDL, whereas LCAT adds cholesteryl ester to LDL in mice.
sterol o-acyltransferase deficiency
ACAT2 deficiency limits cholesterol absorption in the cholesterol-fed mouse: impact on hepatic cholesterol homeostasis.
sterol o-acyltransferase deficiency
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.
sterol o-acyltransferase deficiency
Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow.
sterol o-acyltransferase deficiency
Intestine specific MTP deficiency with global ACAT2 gene ablation lowers acute cholesterol absorption with chylomicrons and high density lipoproteins.
sterol o-acyltransferase deficiency
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.
sterol o-acyltransferase deficiency
Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1.
sterol o-acyltransferase deficiency
Myeloid Acyl-CoA:Cholesterol Acyltransferase 1 Deficiency Reduces Lesion Macrophage Content and Suppresses Atherosclerosis Progression.
sterol o-acyltransferase deficiency
Ophthalmological findings in three patients with cholesterol acyltransferase deficiency syndrome before and after kidney transplantation.
sterol o-acyltransferase deficiency
Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1.
sterol o-acyltransferase deficiency
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.
sterol o-acyltransferase deficiency
SOAT1 deficiency attenuates atherosclerosis by regulating inflammation and cholesterol transportation via HO-1 pathway.
sterol o-acyltransferase deficiency
TLR4-mediated inflammation promotes foam cell formation of vascular smooth muscle cell by upregulating ACAT1 expression.
sterol o-acyltransferase deficiency
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Stomach Neoplasms
Usnic acid induces apoptosis in human gastric cancer cells through ROS generation and DNA damage and causes up-regulation of DNA-PKcs and ?-H2A.X phosphorylation.
Sunburn
Photoprotection by Cichorum endivia extracts: prevention of UVB-induced erythema, pyrimidine dimer formation and IL-6 expression.
Tangier Disease
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Tauopathies
Acyl-coenzyme A:cholesterol acyltransferase 1 blockage enhances autophagy in the neurons of triple transgenic Alzheimer's disease mouse and reduces human P301L-tau content at the presymptomatic stage.
triacylglycerol lipase deficiency
The beta very low density lipoprotein present in hepatic lipase deficiency competitively inhibits low density lipoprotein binding to fibroblasts and stimulates fibroblast acyl-CoA:cholesterol acyltransferase.
triacylglycerol lipase deficiency
[Familial alpha lipoprotein deficiency. Tangier disease, familial hypoalphalipoproteinemia and familial deficiency of lecithin cholesterol acyltransferase deficiency]
Tuberculosis
Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate.
Uterine Cervical Neoplasms
A comparative study of digital PCR and real-time qPCR for the detection and quantification of HPV mRNA in sentinel lymph nodes of cervical cancer patients.
Uterine Cervical Neoplasms
Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1.
Uterine Cervical Neoplasms
Anti-neoplastic selenium nanoparticles from Idiomarina sp. PR58-8.
Uterine Cervical Neoplasms
Antineoplastic potential and chemical evaluation of essential oils from leaves and flowers of Tagetes ostenii Hicken.
Uterine Cervical Neoplasms
Bacillus thuringiensis toxins are cytotoxic to cervical cancer (HeLa) but not to breast cancer (MCF7) cells.
Uterine Cervical Neoplasms
Biotin Decorated Gold Nanoparticles for Targeted Delivery of a Smart-Linked Anticancer Active Copper Complex: In Vitro and In Vivo Studies.
Uterine Cervical Neoplasms
Crucial role of cytokines in sex steroid formation in normal and tumoral tissues.
Uterine Cervical Neoplasms
Cudrania tricuspidata Stem Extract Induces Apoptosis via the Extrinsic Pathway in SiHa Cervical Cancer Cells.
Uterine Cervical Neoplasms
Cytotoxicity of Ficus Crocata Extract on Cervical Cancer Cells and Protective Effect against Hydrogen Peroxide-Induced Oxidative Stress in HaCaT Non-Tumor Cells.
Uterine Cervical Neoplasms
Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.
Uterine Cervical Neoplasms
Down modulation of IL-18 expression by human papillomavirus type 16 E6 oncogene via binding to IL-18.
Uterine Cervical Neoplasms
Ectonucleotidase expression profile and activity in human cervical cancer cell lines.
Uterine Cervical Neoplasms
Epigenetic activation of WHSC1 functions as an oncogene and is associated with poor prognosis in cervical cancer.
Uterine Cervical Neoplasms
Expression/localization patterns of sirtuins (SIRT1, SIRT2, and SIRT7) during progression of cervical cancer and effects of sirtuin inhibitors on growth of cervical cancer cells.
Uterine Cervical Neoplasms
Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines.
Uterine Cervical Neoplasms
Let?7a suppresses cell proliferation via the TGF??/SMAD signaling pathway in cervical cancer.
Uterine Cervical Neoplasms
Long non-coding RNA cancer susceptibility candidate 2 inhibits the cell proliferation, invasion and angiogenesis of cervical cancer through the MAPK pathway.
Uterine Cervical Neoplasms
Mechanism of hydrogen on cervical cancer suppression revealed by high?throughput RNA sequencing.
Uterine Cervical Neoplasms
Novel 2-benzylthio-5-(1,3,4-oxadiazol-2-yl)benzenesulfonamides with anticancer activity: Synthesis, QSAR study, and metabolic stability.
Uterine Cervical Neoplasms
Oscillations of ultra-weak photon emission from cancer and non-cancer cells stressed by culture medium change and TNF-?.
Uterine Cervical Neoplasms
Oxidative Stress Triggered by Apigenin Induces Apoptosis in a Comprehensive Panel of Human Cervical Cancer-Derived Cell Lines.
Uterine Cervical Neoplasms
Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Uterine Cervical Neoplasms
Proteomic analysis of progressive factors in uterine cervical cancer.
Uterine Cervical Neoplasms
Reciprocal transactivation of Merkel cell polyomavirus and high-risk human papillomavirus promoter activities and increased expression of their oncoproteins.
Uterine Cervical Neoplasms
Selective photodynamic effects on cervical cancer cells provided by P123 Pluronic®-based nanoparticles modulating hypericin delivery.
Uterine Cervical Neoplasms
Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence.
Uterine Cervical Neoplasms
The new-generation proteasome inhibitor oprozomib increases the sensitivity of cervical cancer cells to cisplatin-induced apoptosis.
Uterine Cervical Neoplasms
Ultrasound irradiation inhibits proliferation of cervical cancer cells by initiating endoplasmic reticulum stress-mediated apoptosis and triggering phosphorylation of JNK.
Uterine Neoplasms
Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer.
Vaccinia
Human papillomavirus type 16 (HPV 16) E7 and major histocompatibility complex (MHC) class I and II expression in human keratinocytes in culture.
Vaginitis
Phenotypic and genotypic characteristics of Candida albicans isolates from bloodstream and mucosal infections.
Vascular Diseases
Multi-Omics Analysis to Examine Gene Expression and Metabolites From Multisite Adipose-Derived Mesenchymal Stem Cells.
Vesicular Stomatitis
Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line.
Virus Diseases
Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells.
Virus Diseases
HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics.
Virus Diseases
Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line.
Vitiligo
Decreased SUMOylation of the retinoblastoma protein in keratinocytes during the pathogenesis of vitiligo.
Vitiligo
miR-9 regulates melanocytes adhesion and migration during vitiligo repigmentation induced by UVB treatment.
Wound Infection
Cationic-bilayered nanoemulsion of fusidic acid: an investigation on eradication of methicillin-resistant Staphylococcus aureus 33591 infection in burn wound.
Xanthomatosis
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.
Xanthomatosis
Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow.
Xanthomatosis
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.
Xeroderma Pigmentosum
Phloroglucinol enhances the repair of UVB radiation-induced DNA damage via promotion of the nucleotide excision repair system in vitro and in vivo.
Zika Virus Infection
Insights into ZIKV-Mediated Innate Immune Responses in Human Dermal Fibroblasts and Epidermal Keratinocytes.
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