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EC Tree
The enzyme appears in viruses and cellular organisms
Synonyms
1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase, 1-alkenyl-GPC acyltransferase, lyso-PmeC ATase, lysophosphatidylcholine acyltransferase, lysoplasmenylcholine acyltransferase, O-1-alkenylglycero-3-phosphorylcholine acyltransferase, synthase, plasmalogen,
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1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase
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1-alkenyl-GPC acyltransferase
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lysophosphatidylcholine acyltransferase
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lysoplasmenylcholine acyltransferase
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O-1-alkenylglycero-3-phosphorylcholine acyltransferase
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synthase, plasmalogen
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acyl-CoA + 1-O-(alk-1-enyl)glycero-3-phosphocholine = CoA + plasmenylcholine
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Acyl group transfer
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acyl-CoA:1-O-(alk-1-enyl)-glycero-3-phosphocholine 2-O-acyltransferase
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arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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heart enzyme is highly specific for linoleoyl-CoA
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
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arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
arachidonoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-arachidonoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
oleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine
CoA + 1-alkenyl-2-oleoyl-glycero-3-phosphorylcholine
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r
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1-acyl-glycero-3-phosphorylcholine
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non competitive
Ca2+
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mitochondrial enzyme
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Ca2+
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enhances activity of microsomal enzyme
Mg2+
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enhances activity of microsomal enzyme
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0.0265 - 0.0297
1-alkenyl-glycero-3-phosphorylcholine
0.00077 - 0.00091
oleoyl-CoA
0.0265
1-alkenyl-glycero-3-phosphorylcholine
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submandibular gland
0.0267
1-alkenyl-glycero-3-phosphorylcholine
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sublingual gland
0.0297
1-alkenyl-glycero-3-phosphorylcholine
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0.00077
oleoyl-CoA
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submandibular gland
0.0008 - 0.0009
oleoyl-CoA
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0.00086
oleoyl-CoA
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sublingual gland
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additional information
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specific activity for various acyl-CoAs
additional information
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specific activity for various acyl-CoAs
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7.4
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assay at
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20
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assay at
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guinea pig
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brenda
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brenda
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brenda
male Wistar
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brenda
Sprague Dawley
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brenda
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brenda
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brenda
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brenda
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brenda
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brenda
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brenda
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brenda
additional information
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no activity in rabbit brain and heart
brenda
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brenda
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of muscle
brenda
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brenda
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brenda
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PCAT2_DANRE
529
1
59424
Swiss-Prot
Secretory Pathway (Reliability: 2 )
PCAT2_HUMAN
544
1
60208
Swiss-Prot
other Location (Reliability: 3 )
PCAT2_MOUSE
544
1
60254
Swiss-Prot
other Location (Reliability: 3 )
PCAT2_RAT
544
1
59829
Swiss-Prot
other Location (Reliability: 3 )
PCAT1_DANRE
517
1
58727
Swiss-Prot
Mitochondrion (Reliability: 2 )
PCAT1_HUMAN
534
1
59151
Swiss-Prot
Mitochondrion (Reliability: 2 )
PCAT1_MOUSE
534
1
59744
Swiss-Prot
Mitochondrion (Reliability: 2 )
PCAT1_RAT
534
1
59762
Swiss-Prot
Mitochondrion (Reliability: 2 )
LPCT1_ARATH
398
1
44713
Swiss-Prot
other Location (Reliability: 2 )
LPCT2_ARATH
539
0
61022
Swiss-Prot
other Location (Reliability: 2 )
G7L639_MEDTR
382
2
42842
TrEMBL
other Location (Reliability: 3 )
A0A7C9ALK0_OPUST
323
0
37200
TrEMBL
Mitochondrion (Reliability: 4 )
A0A072TP83_MEDTR
530
2
60576
TrEMBL
other Location (Reliability: 3 )
A0A7C9AHI8_OPUST
238
1
26957
TrEMBL
other Location (Reliability: 5 )
A0A2P6SGG2_ROSCH
611
2
69475
TrEMBL
other Location (Reliability: 5 )
A0A2G9H4L8_9LAMI
383
2
43396
TrEMBL
other Location (Reliability: 2 )
A0A7C9AJA1_OPUST
549
1
62763
TrEMBL
other Location (Reliability: 5 )
A0A2P6PYL4_ROSCH
378
2
42209
TrEMBL
other Location (Reliability: 3 )
A0A072VER2_MEDTR
383
2
42981
TrEMBL
other Location (Reliability: 3 )
A0A2G9HFA5_9LAMI
383
2
43689
TrEMBL
other Location (Reliability: 3 )
A0A2G9GD04_9LAMI
394
1
44424
TrEMBL
other Location (Reliability: 2 )
A0A7C9AJZ8_OPUST
328
1
37419
TrEMBL
other Location (Reliability: 5 )
A0A7C9AI82_OPUST
419
1
47546
TrEMBL
other Location (Reliability: 5 )
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55
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90% loss of activity after 1 min
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partial
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Choy, P.C.; Skrzypczak, M.; Lee, D.; Jay, F.T.
Acyl-GPC and alkenyl/alkyl-GPC:acyl-CoA acyltransferases
Biochim. Biophys. Acta
1348
124-133
1997
Cavia porcellus
brenda
Waku, K.; Lands, W.E.M.
Acyl coenzyme A:1-alkenyl-glycero-3-phosphorylcholine acyltransferase action in plasmalogen biosynthesis
J. Biol. Chem.
243
2654-2659
1968
Oryctolagus cuniculus, Homo sapiens
brenda
Kameyama, Y.; Shinkai, A.
Characterization of 1-alkenyl-sn-glycero-3-phosphorylcholine acyltransferase activity in the microsomes from rat parotid gland
Shika Kiso Igakkai Zasshi
42
319-325
2000
Rattus norvegicus
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brenda
Okada, A.
Composition of ether-linked glycerophospholipids and properties of microsomal lysoplasmenylcholine acyltransferase in rat submandibular and sublingual glands
Shika Kiso Igakkai Zasshi
33
428-445
1991
Rattus norvegicus
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brenda
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